{"meta":{"query_hash":"de980f233f91","filters":{"topic":"Autophagy in Disease and Therapy"},"cohort_total":1599,"direct_labels_cover":3,"predictions_cover":1599,"exported":1599,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/de980f233f91","api":"https://metacan.xera.ac/api/v1/cohort?topic=Autophagy+in+Disease+and+Therapy"},"results":[{"id":"W1160967900","doi":"10.1096/fasebj.29.1_supplement.821.4","title":"Acute Exercise‐Induced Mitophagy is Mediated in Part by PGC‐1α","year":2015,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Mitophagy; Mitochondrial biogenesis; Autophagy; TFAM; Mitochondrion; Organelle biogenesis; Internal medicine; Endocrinology; Endurance training; Cell biology; AMPK; Skeletal muscle; Biology; Biogenesis; Chemistry; Medicine; Gene; Apoptosis; Biochemistry","score_opus":0.03208019348972875,"score_gpt":0.2954469029113833,"score_spread":0.2633667094216546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1160967900","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99100196,0.0036625676,0.000020095997,0.0031678088,0.0005476613,0.00021936787,0.000028063385,0.000034933677,0.0013175413],"genre_scores_gemma":[0.9927896,0.0011067877,0.000031876287,0.003402072,0.0005180414,0.000011932143,0.000025943427,0.000030049141,0.0020836983],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985123,0.00010469576,0.0003539472,0.00015668853,0.00050228107,0.00037003017],"domain_scores_gemma":[0.9988824,0.000052408257,0.00013922562,0.00031773307,0.00010739731,0.00050083303],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005327171,0.00017811089,0.0003271184,0.00010011553,0.00009889188,0.000040246025,0.00024238187,0.00010834342,0.0007847185],"category_scores_gemma":[0.000052874722,0.00011037106,0.00012867182,0.00024883,0.00006414306,0.00012289447,0.000032125685,0.0005481495,0.0003141195],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037171994,0.000999059,0.0077900593,0.00002258508,0.0009331521,0.0026453591,0.007920781,0.000008086446,0.43367895,0.000030635372,0.52692217,0.015331979],"study_design_scores_gemma":[0.017593555,0.00091366004,0.0054427693,0.0004493151,0.0006112262,0.0015803818,0.0020464587,0.000499025,0.94452,0.0021662964,0.023671135,0.0005061539],"about_ca_topic_score_codex":0.00002701773,"about_ca_topic_score_gemma":0.0000022495603,"teacher_disagreement_score":0.5108411,"about_ca_system_score_codex":0.00009904659,"about_ca_system_score_gemma":0.00028321054,"threshold_uncertainty_score":0.85921174},"labels":[],"label_agreement":null},{"id":"W1189365228","doi":"10.1096/fasebj.27.1_supplement.533.6","title":"BNIP3 regulates mitophagy and apoptosis in delayed neuronal death in stroke","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Manitoba","funders":"Manitoba Health Research Council","keywords":"Neuroprotection; Mitophagy; Autophagy; Apoptosis; Regulator; Cell biology; Programmed cell death; Western blot; Biology; Neurotoxicity; TUNEL assay; Gene; Neuroscience; Medicine; Internal medicine; Genetics","score_opus":0.01394510217515448,"score_gpt":0.25247733333317557,"score_spread":0.23853223115802108,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1189365228","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99638635,0.0013929098,0.000013751145,0.0015057087,0.00009542107,0.00019638144,0.0000032692842,0.000010637719,0.00039557714],"genre_scores_gemma":[0.9978062,0.0004942618,0.00012946257,0.0008904579,0.00018232776,0.000010613906,0.0000022450702,0.000014904415,0.0004695499],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99906504,0.00009783007,0.00026032233,0.000119953445,0.00019503672,0.00026183794],"domain_scores_gemma":[0.9995031,0.000083646104,0.00006974638,0.00015278919,0.000034093293,0.00015665015],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002202782,0.00011991789,0.0001975005,0.00013885839,0.00007469606,0.000044906403,0.00010714219,0.00005463971,0.00048003483],"category_scores_gemma":[0.000029555365,0.00007548164,0.000063120024,0.00010739356,0.000060991617,0.00012835662,0.000027675407,0.00040637905,0.0000263993],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011639205,0.00055293215,0.49611175,0.00003268508,0.00026768344,0.00035085742,0.0016068699,0.00012365413,0.47376332,0.000413876,0.0013401322,0.024272313],"study_design_scores_gemma":[0.0030945148,0.00026529792,0.90105134,0.00008181496,0.000039719016,0.00041767093,0.00025434347,0.0007921552,0.09118791,0.0026274826,0.00007846563,0.00010926425],"about_ca_topic_score_codex":0.00012383408,"about_ca_topic_score_gemma":0.000010503801,"teacher_disagreement_score":0.4049396,"about_ca_system_score_codex":0.000042935808,"about_ca_system_score_gemma":0.00006439653,"threshold_uncertainty_score":0.5256045},"labels":[],"label_agreement":null},{"id":"W1218953169","doi":"10.1593/neo.07842","title":"BH3 Mimetics Reactivate Autophagic Cell Death in Anoxia-Resistant Malignant Glioma Cells","year":2008,"lang":"en","type":"article","venue":"Neoplasia","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Autophagy; Glioma; Programmed cell death; Cancer research; Cell biology; Biology; Medicine; Chemistry; Apoptosis; Biochemistry","score_opus":0.017614682324050036,"score_gpt":0.2486254195487619,"score_spread":0.23101073722471188,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1218953169","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867398,0.0013067522,0.00004156951,0.00012908065,0.00023265717,0.00040367106,0.00001881661,0.0001230928,0.011004554],"genre_scores_gemma":[0.9950829,0.0005086883,0.0009445514,0.0005419529,0.00013681033,0.000024193438,0.000023342098,0.000057199555,0.0026803473],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99818754,0.00006511516,0.0004086901,0.00043332594,0.00039486084,0.0005104367],"domain_scores_gemma":[0.99891865,0.00007875534,0.00011676215,0.00054984057,0.000057210793,0.00027878306],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012023608,0.00029129823,0.0004520461,0.00020122998,0.0000991255,0.000013307284,0.00015638139,0.00018111899,0.00037808],"category_scores_gemma":[0.00001768267,0.00025053753,0.00015970843,0.0004124485,0.00008306763,0.00008571891,0.000038199345,0.00027365936,0.00034583212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010771095,0.0011998772,0.017759508,0.00012805754,0.00007603793,0.013460779,0.0008266552,0.000015323134,0.9623745,0.00034424066,0.0020611363,0.0006767571],"study_design_scores_gemma":[0.0038799956,0.00048872596,0.1295003,0.000119506636,0.000081413506,0.0003918329,0.000073901494,0.00023835656,0.8562125,0.00030961295,0.008389185,0.00031464794],"about_ca_topic_score_codex":0.00010895164,"about_ca_topic_score_gemma":0.000008019145,"teacher_disagreement_score":0.11174079,"about_ca_system_score_codex":0.00012729748,"about_ca_system_score_gemma":0.00026754808,"threshold_uncertainty_score":0.9999947},"labels":[],"label_agreement":null},{"id":"W1251748139","doi":"10.1097/mib.0000000000000553","title":"Microbial Disruption of Autophagy Alters Expression of the RISC Component AGO2, a Critical Regulator of the miRNA Silencing Pathway","year":2015,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Canada; Canadian Association of Gastroenterology","keywords":"Gene silencing; Regulator; microRNA; Cell biology; Autophagy; Argonaute; Biology; RNA-induced silencing complex; Chemistry; Small interfering RNA; Genetics; Apoptosis; Gene; Transfection","score_opus":0.016369865919940253,"score_gpt":0.2676992826731991,"score_spread":0.2513294167532588,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1251748139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971897,0.0012801135,0.00003515719,0.0001895291,0.00048579363,0.000510332,0.00017176113,0.000032713604,0.000104885396],"genre_scores_gemma":[0.999517,0.000013616865,0.00006027277,0.00013111475,0.00014872591,0.00002261922,0.0000096477015,0.0000255435,0.00007142881],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980485,0.00024289891,0.0006250392,0.00022286244,0.0006436199,0.00021707336],"domain_scores_gemma":[0.99824077,0.00012920232,0.000370488,0.00077419536,0.00024336186,0.00024199307],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001775906,0.00019648901,0.00036652165,0.000063959094,0.00008340363,0.0000071529407,0.00030585198,0.000094472605,0.00008546165],"category_scores_gemma":[0.00036630378,0.00011583859,0.00041893302,0.00012299539,0.000646725,0.00011237785,0.00016115731,0.00013049628,0.0000048386037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014339394,0.0008457393,0.06474639,0.0008377042,0.00010074561,0.00003525661,0.0013493723,0.00018659153,0.92788017,0.0007144126,0.0015028514,0.00036683967],"study_design_scores_gemma":[0.0014055109,0.00007211163,0.48363206,0.00096454914,0.00017368085,0.000008376659,0.00031732835,0.00020380167,0.512498,0.00046117956,0.00016680459,0.00009657729],"about_ca_topic_score_codex":0.000023310598,"about_ca_topic_score_gemma":0.0000019543095,"teacher_disagreement_score":0.41888568,"about_ca_system_score_codex":0.00007371874,"about_ca_system_score_gemma":0.0004823646,"threshold_uncertainty_score":0.47237608},"labels":[],"label_agreement":null},{"id":"W139497788","doi":"10.1007/978-1-4614-5915-6_8","title":"Autophagy and Cell Death to Target Cancer Cells: Exploiting Synthetic Lethality as Cancer Therapies","year":2013,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Atlantic Cancer Research Institute; Université de Moncton","funders":"","keywords":"Autophagy; Necroptosis; Cancer cell; Programmed cell death; Cancer; Cancer research; Synthetic lethality; Biology; Apoptosis; DNA repair; Biochemistry; Genetics; Gene","score_opus":0.0731298857718768,"score_gpt":0.44345286609822165,"score_spread":0.37032298032634486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W139497788","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.026721794,0.9701204,0.000009476762,0.00022062297,0.0005415104,0.001256135,0.000035871737,0.000042280793,0.001051916],"genre_scores_gemma":[0.012896274,0.98257893,0.00039933703,0.0017105286,0.0005771594,0.0014838779,0.000043005923,0.000054788725,0.00025611356],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978077,0.00018411063,0.0006219299,0.000784306,0.00012891901,0.0004730811],"domain_scores_gemma":[0.99890655,0.00024501057,0.00024171462,0.0002781859,0.000033531658,0.00029498042],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00015878727,0.0005767165,0.0019443813,0.00022184783,0.00008644864,0.000009335457,0.00015151467,0.0002861108,0.001043155],"category_scores_gemma":[0.000027877579,0.00036551448,0.000109917586,0.00017582801,0.00042793163,0.000112394555,0.00011882063,0.00033859015,0.000015596921],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009654885,0.00021100488,0.00024905062,0.0044048834,0.00017633186,0.000096460426,0.0018077481,4.1318393e-7,0.0096592875,0.00036349258,0.000100368896,0.9828344],"study_design_scores_gemma":[0.0012886067,0.0011733138,0.000022288568,0.010933522,0.00026006013,0.00009765873,0.0016477733,0.000004593059,0.014240164,0.00040975428,0.96943444,0.00048785156],"about_ca_topic_score_codex":0.0008972184,"about_ca_topic_score_gemma":0.000011937818,"teacher_disagreement_score":0.98234653,"about_ca_system_score_codex":0.00014369785,"about_ca_system_score_gemma":0.00013214718,"threshold_uncertainty_score":0.99987966},"labels":[],"label_agreement":null},{"id":"W1431781896","doi":"10.1096/fasebj.29.1_supplement.715.46","title":"The Lipid Kinase PIKfyve Controls Lysosome Gene Transcription","year":2015,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Toronto Metropolitan University","funders":"","keywords":"TFEB; Lysosome; mTORC1; Cell biology; Autophagy; Basic helix-loop-helix leucine zipper transcription factors; Cytosol; Biology; Transcription factor; Mechanistic target of rapamycin; Chemistry; Phosphorylation; Biochemistry; Gene; Enzyme","score_opus":0.030559320698956775,"score_gpt":0.276455225885138,"score_spread":0.2458959051861812,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1431781896","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98049456,0.007253119,0.0007898596,0.008712142,0.00088049594,0.00027263016,0.000008224809,0.000037051555,0.0015519336],"genre_scores_gemma":[0.99325216,0.0007858276,0.000048563437,0.002216186,0.0020326888,0.000010790875,0.000004943936,0.000019641006,0.0016291747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987521,0.00017761016,0.00026361045,0.000094782175,0.0004266296,0.00028523608],"domain_scores_gemma":[0.99898636,0.000082083294,0.000118275064,0.000309192,0.00015484443,0.00034924716],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00093096896,0.00012851284,0.00018361835,0.00003760904,0.000404466,0.00008959614,0.00021296504,0.000051257823,0.00012363566],"category_scores_gemma":[0.00007905679,0.000059284834,0.00019153862,0.00009643714,0.00013424423,0.0000987436,0.000010758367,0.0003934585,0.00012980716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004454347,0.0003406073,0.0011226226,0.000010176519,0.0007086359,0.00052043464,0.0025146035,0.00008301156,0.9421054,0.0017157932,0.015465075,0.030959299],"study_design_scores_gemma":[0.03809382,0.0033330184,0.024236144,0.00025713767,0.0018962366,0.009062486,0.004889999,0.0024702437,0.7210626,0.028014194,0.16595319,0.00073092],"about_ca_topic_score_codex":0.0000072227654,"about_ca_topic_score_gemma":0.0000020530804,"teacher_disagreement_score":0.22104278,"about_ca_system_score_codex":0.00008117688,"about_ca_system_score_gemma":0.0002208444,"threshold_uncertainty_score":0.31108662},"labels":[],"label_agreement":null},{"id":"W145254029","doi":"10.1096/fasebj.25.1_supplement.1106.5","title":"Autophagy signaling following denervation‐induced muscle disuse in young and old animals","year":2011,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Autophagy; Denervation; Muscle atrophy; Sarcopenia; Endocrinology; Atrophy; Internal medicine; Ageing; Skeletal muscle; Biology; Chemistry; Medicine; Biochemistry; Apoptosis","score_opus":0.044711737861436895,"score_gpt":0.2802373545852883,"score_spread":0.23552561672385142,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W145254029","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99781054,0.0008805695,0.0000790433,0.00018512266,0.00019665166,0.00014216338,0.0000011319369,0.000025845637,0.00067891827],"genre_scores_gemma":[0.99884033,0.00006691168,0.00027253127,0.0003834722,0.00022155706,0.000005725933,0.0000012744026,0.000021154015,0.000187046],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990422,0.00008844008,0.000282342,0.00012711238,0.00021655607,0.0002433412],"domain_scores_gemma":[0.99949247,0.00005202735,0.00010478281,0.00016671677,0.000034380733,0.00014964974],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056566665,0.00012264549,0.00019907212,0.000104033694,0.00019549207,0.000039492745,0.00011412792,0.00005506798,0.00021269699],"category_scores_gemma":[0.0000583104,0.00008177147,0.00011126149,0.00015211862,0.000034838748,0.00015699722,0.000027082988,0.00030538376,0.0000101830465],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025746538,0.00014285312,0.11820497,0.000013185334,0.00018177621,0.0007747711,0.0054999082,0.000005659498,0.8670087,0.0005041985,0.00001854547,0.0073879627],"study_design_scores_gemma":[0.0026340415,0.00022391771,0.7717443,0.00018496103,0.0001662225,0.00038889796,0.00078253547,0.00037646975,0.22079597,0.002538686,0.000015936528,0.0001480494],"about_ca_topic_score_codex":0.000093604925,"about_ca_topic_score_gemma":0.0000139069125,"teacher_disagreement_score":0.6535393,"about_ca_system_score_codex":0.000046693356,"about_ca_system_score_gemma":0.000069771566,"threshold_uncertainty_score":0.33345437},"labels":[],"label_agreement":null},{"id":"W147563342","doi":"10.1007/978-1-4614-1680-7_11","title":"Autophagy and Self-Defense","year":2012,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fonds de Recherche du Québec - Santé","keywords":"Autophagy; Cell biology; Inflammation; Biology; Organelle; Immune system; Mechanism (biology); Innate immune system; Antigen presentation; Homeostasis; Acquired immune system; Programmed cell death; Immunology; Biochemistry; Apoptosis; T cell","score_opus":0.062353149121561105,"score_gpt":0.43585875726706225,"score_spread":0.37350560814550116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W147563342","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010073766,0.9953733,0.000002080373,0.00004778894,0.000443188,0.0005723324,0.0000067639226,0.000055833407,0.0024913144],"genre_scores_gemma":[0.0048571415,0.9934419,0.00020887138,0.00052883493,0.0006394164,0.00012907703,0.00009489042,0.00003169104,0.000068212095],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985707,0.000112364265,0.00046848992,0.00043384175,0.00007154635,0.00034310363],"domain_scores_gemma":[0.9992226,0.00017458748,0.00015532068,0.00021707686,0.000011185193,0.00021924725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014647335,0.00039486014,0.0016346611,0.00021185944,0.0000438504,0.0000026592488,0.000072539806,0.0002989076,0.00017566077],"category_scores_gemma":[0.000020896221,0.00024412322,0.000085272535,0.00014188708,0.0004650361,0.00009195376,0.0000815691,0.00027495064,0.0000119630295],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044258122,0.00027623915,0.000135238,0.0029235072,0.00011244684,0.000065661356,0.00040805427,1.8948996e-9,0.000062329374,0.0017293734,0.000034873938,0.99420804],"study_design_scores_gemma":[0.001276666,0.0009887873,0.000028748136,0.0028446517,0.0004245098,0.0005567622,0.00023754002,8.794644e-7,0.00008081687,0.00019395848,0.9931422,0.00022450513],"about_ca_topic_score_codex":0.000012550765,"about_ca_topic_score_gemma":0.0000011784343,"teacher_disagreement_score":0.9939835,"about_ca_system_score_codex":0.000058820984,"about_ca_system_score_gemma":0.00004585495,"threshold_uncertainty_score":0.9955056},"labels":[],"label_agreement":null},{"id":"W1488820662","doi":"10.1080/15548627.2015.1040972","title":"Molecular interactions of the<i>Saccharomyces cerevisiae</i>Atg1 complex provide insights into assembly and regulatory mechanisms","year":2015,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Biology; Autophagy-related protein 13; Saccharomyces cerevisiae; CTD; Autophagy; Protein subunit; Cell biology; Scaffold protein; Phosphorylation; Biochemistry; Protein phosphorylation; Protein kinase A; Yeast; Gene; Signal transduction","score_opus":0.024142330592075836,"score_gpt":0.28870933573163715,"score_spread":0.26456700513956133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1488820662","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99280035,0.0027981391,0.0006880009,0.0008284987,0.00025935934,0.0004654942,0.0000033364781,0.0000768117,0.002079975],"genre_scores_gemma":[0.99708676,0.000040850093,0.0010821009,0.001230275,0.0000662638,0.000029225059,0.000010399901,0.000029606224,0.00042451863],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987881,0.000099408484,0.00031572962,0.00027189395,0.00035069577,0.0001741399],"domain_scores_gemma":[0.99887,0.000043238935,0.00017140899,0.0005425386,0.00015387773,0.00021889847],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012087412,0.00018507935,0.00033985486,0.00009231899,0.00008333825,0.00001941146,0.00016703524,0.00007674234,0.0000648742],"category_scores_gemma":[0.00006991981,0.00013164534,0.0001275629,0.00020075336,0.00013834354,0.0001516508,0.00011197336,0.00015889104,0.000019068206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020435659,0.00039972644,0.00047083618,0.00022125743,0.00038011302,0.00010812359,0.0025374913,0.000021304522,0.9246277,0.060515624,0.002161982,0.008351457],"study_design_scores_gemma":[0.0025597275,0.0004033139,0.037181724,0.00024807727,0.00028429556,0.00013128435,0.00049540534,0.0012923821,0.8990192,0.03846444,0.019646617,0.00027353756],"about_ca_topic_score_codex":0.00007256832,"about_ca_topic_score_gemma":0.000009858455,"teacher_disagreement_score":0.03671089,"about_ca_system_score_codex":0.00006187775,"about_ca_system_score_gemma":0.00021744944,"threshold_uncertainty_score":0.5368341},"labels":[],"label_agreement":null},{"id":"W1501422236","doi":"10.4049/jimmunol.1402571","title":"Survival of Effector CD8+ T Cells during Influenza Infection Is Dependent on Autophagy","year":2015,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Victoria; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Effector; Autophagy; Cytotoxic T cell; CD8; Virology; Biology; Immunology; Cell biology; Immune system; Genetics; Apoptosis","score_opus":0.024931304691049722,"score_gpt":0.29840064918405645,"score_spread":0.27346934449300675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1501422236","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962221,0.0021344463,0.000044903907,0.00017675101,0.00095389376,0.00012333943,0.0000025697152,0.000012077124,0.00032992085],"genre_scores_gemma":[0.9988806,0.0004251382,0.000014246984,0.00030289948,0.0001983806,0.0000011450229,4.5577175e-7,0.000014817743,0.00016231604],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99883926,0.00026365835,0.00040237594,0.00006530249,0.00026871575,0.00016067304],"domain_scores_gemma":[0.99889696,0.00013927733,0.00041127807,0.00026074355,0.00021546152,0.000076291304],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00063847686,0.000114785995,0.00035862252,0.00015415398,0.00004110436,0.0000038339426,0.00013748305,0.00009885548,0.00013424625],"category_scores_gemma":[0.00009489818,0.00007061343,0.00013150931,0.00010212667,0.00009750077,0.00006197216,0.00003565897,0.00035392094,0.000065710046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0087544285,0.00049117935,0.006920259,0.000054178094,0.0011303396,0.00010663477,0.0018745331,0.00025195847,0.97828513,0.000082521896,0.00030519333,0.0017436413],"study_design_scores_gemma":[0.004919944,0.0024903866,0.1750721,0.00009819638,0.00019963099,0.00043045793,0.00012811158,0.000010318851,0.8157452,0.00021684908,0.0006226615,0.00006619589],"about_ca_topic_score_codex":0.000055094242,"about_ca_topic_score_gemma":0.0000017137563,"teacher_disagreement_score":0.16815184,"about_ca_system_score_codex":0.000100687175,"about_ca_system_score_gemma":0.00014248017,"threshold_uncertainty_score":0.2879532},"labels":[],"label_agreement":null},{"id":"W1504365021","doi":"10.1038/cdd.2015.88","title":"Nuclear ULK1 promotes cell death in response to oxidative stress through PARP1","year":2015,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Centre Hospitalier Universitaire de Québec; Beckman Research Institute, City of Hope; American Society of Hematology; St. Jude Children's Research Hospital; National Heart, Lung, and Blood Institute; University of Minnesota; Moffitt Cancer Center","keywords":"Autophagy; ULK1; Cell biology; Programmed cell death; Oxidative stress; Protein kinase A; DNA damage; Intracellular; Biology; Reactive oxygen species; Kinase; Chemistry; Apoptosis; Biochemistry; AMPK; DNA","score_opus":0.028123002303522538,"score_gpt":0.27856313080030126,"score_spread":0.2504401284967787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1504365021","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99627954,0.00044770227,0.00041531314,0.00019879949,0.00007728381,0.00048814944,0.000017198705,0.00004848919,0.0020275097],"genre_scores_gemma":[0.99823576,0.00008426409,0.00051174633,0.00036195744,0.00006372288,0.000022134003,0.00007889603,0.00001959364,0.0006219172],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990243,0.00011112698,0.00018589426,0.00027078195,0.00019369152,0.00021420915],"domain_scores_gemma":[0.9993663,0.00005288327,0.000062624276,0.00020141224,0.0000665039,0.00025031212],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012595952,0.00015680649,0.00021367181,0.0000952299,0.000049876297,0.000034679662,0.000056225403,0.00009088715,0.00007666254],"category_scores_gemma":[0.000056602228,0.00013154521,0.000039838484,0.000112344904,0.000016146876,0.00012481888,0.00003494317,0.000103692524,0.000055320994],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.020217806,0.004896933,0.64180505,0.0005630503,0.00013662605,0.00027540073,0.04229503,0.000043449778,0.28181782,0.0018288336,0.0018260782,0.0042939405],"study_design_scores_gemma":[0.0060893176,0.0012203223,0.77729094,0.00014622453,0.00011741274,0.000004294018,0.00103947,0.0010181335,0.209179,0.0024391233,0.00114633,0.0003094536],"about_ca_topic_score_codex":0.000058216603,"about_ca_topic_score_gemma":0.0000058274877,"teacher_disagreement_score":0.13548587,"about_ca_system_score_codex":0.000062604835,"about_ca_system_score_gemma":0.000064488995,"threshold_uncertainty_score":0.5364258},"labels":[],"label_agreement":null},{"id":"W1505554680","doi":"10.1096/fasebj.28.1_supplement.234.2","title":"The function of PINK1 and parkin in mitochondrial quality control (234.2)","year":2014,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"PINK1; Parkin; Mitophagy; Mitochondrion; Cell biology; Ubiquitin ligase; Biology; Autophagy; Cytosol; Ubiquitin; Biochemistry; Parkinson's disease; Medicine; Enzyme; Disease; Gene; Internal medicine","score_opus":0.012998572779272995,"score_gpt":0.276578071433214,"score_spread":0.263579498653941,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1505554680","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942487,0.001254393,0.0017257759,0.0017167751,0.00042589667,0.0001459211,0.0000024054266,0.000005785957,0.00047435297],"genre_scores_gemma":[0.99845046,0.00018621684,0.00001713276,0.00058661896,0.00062097167,0.0000036757854,7.787278e-7,0.0000058166606,0.00012833874],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990127,0.0003278848,0.0002684814,0.000064259766,0.000195894,0.00013077965],"domain_scores_gemma":[0.9991944,0.00036369273,0.00015077631,0.0001721682,0.000047750025,0.00007125602],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010488343,0.00006594374,0.00016567725,0.00002813897,0.00014737382,0.000020362815,0.00007505539,0.000037001995,0.00005356434],"category_scores_gemma":[0.00018213707,0.0000313833,0.00006949198,0.000053634107,0.000121702375,0.00003545077,0.000008734747,0.000246169,0.0000042709007],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.024128461,0.00053841295,0.09190882,0.000075927135,0.0009620127,0.000037805934,0.0019549143,0.000087873996,0.6721986,0.011764042,0.004095531,0.19224758],"study_design_scores_gemma":[0.01971512,0.0011081388,0.92018515,0.00016610969,0.00035860203,0.00020291976,0.0006762026,0.0011226056,0.022447592,0.024221793,0.009629411,0.00016634821],"about_ca_topic_score_codex":0.000020223353,"about_ca_topic_score_gemma":0.000013679351,"teacher_disagreement_score":0.82827634,"about_ca_system_score_codex":0.000016059226,"about_ca_system_score_gemma":0.000048734,"threshold_uncertainty_score":0.12797739},"labels":[],"label_agreement":null},{"id":"W1508147782","doi":"10.1158/1538-7445.am2014-156","title":"Abstract 156: Autophagic degradation of granzyme B impairs NK-mediated killing of hypoxic tumor cells","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Autophagy; Granzyme; Biology; Immune system; Granzyme B; Cytotoxic T cell; Cancer research; Tumor microenvironment; Cell biology; Innate immune system; Cancer cell; Interleukin 12; NK-92; Natural killer cell; Interleukin 21; Immunology; T cell; Cancer; CD8; In vitro; Perforin; Apoptosis","score_opus":0.04849117876618802,"score_gpt":0.3699638995978879,"score_spread":0.32147272083169987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1508147782","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956499,0.002410331,0.000057608733,0.0001675983,0.00013048436,0.00041261697,0.000046913603,0.000034458182,0.0010901091],"genre_scores_gemma":[0.99827987,0.0007743273,0.00008985355,0.00007886184,0.00017221394,0.00004890172,0.00004078315,0.000030893087,0.00048427604],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99800885,0.00011750711,0.00038379015,0.00025284456,0.0008527942,0.0003842383],"domain_scores_gemma":[0.99843657,0.0003279215,0.00013880034,0.00039305814,0.0004947536,0.00020886988],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010473792,0.00012404757,0.00035544264,0.00029245508,0.000064971966,0.000008591882,0.00018871247,0.00008779338,0.0010260091],"category_scores_gemma":[0.00016784601,0.00010327435,0.00011966231,0.0005104086,0.00025326124,0.000074856216,0.000032358414,0.0003502351,0.00005354821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000458993,0.0002535043,0.0024054837,0.0006699032,0.00009518803,0.00002177592,0.00023404647,0.00005553291,0.9886079,0.00018982252,0.001049709,0.00595817],"study_design_scores_gemma":[0.0018132786,0.00036408816,0.036906306,0.00037488388,0.000033854143,0.0000026284195,0.00013134713,0.0008898066,0.95765156,0.0004278995,0.0012988765,0.00010548555],"about_ca_topic_score_codex":0.0005311584,"about_ca_topic_score_gemma":0.00001232427,"teacher_disagreement_score":0.034500822,"about_ca_system_score_codex":0.00010923384,"about_ca_system_score_gemma":0.00043650204,"threshold_uncertainty_score":0.99988717},"labels":[],"label_agreement":null},{"id":"W1521411817","doi":"10.1111/j.1742-4658.2009.07366.x","title":"ERK and cell death: Mechanisms of ERK‐induced cell death – apoptosis, autophagy and senescence","year":2009,"lang":"en","type":"review","venue":"FEBS Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1284,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"MAPK/ERK pathway; Cell biology; Autophagy; Programmed cell death; Apoptosis; Senescence; Biology; Kinase; Mitochondrion; Signal transduction; Intracellular; Chemistry; Biochemistry","score_opus":0.04247628943090363,"score_gpt":0.3218456744869401,"score_spread":0.2793693850560365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1521411817","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0073011164,0.99015915,0.00054620416,0.000031845513,0.00031712212,0.0005863122,0.000030344938,0.000033907156,0.0009939763],"genre_scores_gemma":[0.009239005,0.98692065,0.0023591935,0.00021972095,0.00046822397,0.000010465124,0.000023370872,0.00007672625,0.00068264105],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99746376,0.00020199915,0.00089649594,0.0004639155,0.0004993082,0.0004745029],"domain_scores_gemma":[0.99789447,0.00010765996,0.000835572,0.0004083131,0.00013363443,0.00062036066],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043325903,0.0006069348,0.0020699361,0.0003225409,0.00018524438,0.00007388651,0.00023841766,0.00048648685,0.00017881853],"category_scores_gemma":[0.00002833218,0.00045457738,0.00049149094,0.00019300306,0.000048663045,0.00011118778,0.00006853876,0.00096127787,0.000017330773],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018586422,0.0008912291,0.000058869406,0.0187418,0.00066987396,0.0009866914,0.0002507967,3.829913e-7,0.008070365,0.0008379061,0.000655878,0.96865034],"study_design_scores_gemma":[0.019064715,0.0095058335,0.0031618443,0.1018445,0.028931022,0.025792994,0.00029393402,0.0001247685,0.12565453,0.017418649,0.66317374,0.00503349],"about_ca_topic_score_codex":0.000008326624,"about_ca_topic_score_gemma":2.5960534e-7,"teacher_disagreement_score":0.96361685,"about_ca_system_score_codex":0.00009653697,"about_ca_system_score_gemma":0.00062622916,"threshold_uncertainty_score":0.9997906},"labels":[],"label_agreement":null},{"id":"W1523367786","doi":"10.1111/j.1755-5949.2012.00295.x","title":"Excessive Autophagy Contributes to Neuron Death in Cerebral Ischemia","year":2012,"lang":"en","type":"article","venue":"CNS Neuroscience & Therapeutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":264,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Research Manitoba; Manitoba Health Research Council","keywords":"Autophagy; BECN1; Programmed cell death; Cell biology; Ischemia; Immunocytochemistry; Western blot; Hypoxia (environmental); Viability assay; Neuron; Biology; Chemistry; Cell; Apoptosis; Neuroscience; Medicine; Internal medicine; Endocrinology; Biochemistry; Oxygen; Gene","score_opus":0.050948229334376205,"score_gpt":0.3386469389157436,"score_spread":0.2876987095813674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1523367786","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940054,0.0011142662,0.0006831268,0.0017297171,0.0008533188,0.00049147016,0.0000098432465,0.000104110106,0.0010087925],"genre_scores_gemma":[0.96214336,0.00009979975,0.00011009046,0.036745675,0.00016481365,0.000038575992,0.0000035651774,0.000033323824,0.0006608135],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981193,0.00006769886,0.00028420324,0.00039438545,0.0003413184,0.0007930985],"domain_scores_gemma":[0.99897,0.00007024897,0.00007376697,0.0004638079,0.000059896265,0.0003623081],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020400118,0.00023994948,0.0003062031,0.00019784665,0.00012591199,0.00004902269,0.0003075573,0.00009748928,0.000048376307],"category_scores_gemma":[0.00006373178,0.00020376791,0.00009121244,0.0007182849,0.00015907975,0.0002687774,0.00008702473,0.0002868286,0.00006733429],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030763607,0.0009630903,0.28739816,0.000029146371,0.000021940627,0.00010186054,0.0010884729,0.000043053104,0.7005982,0.0029852206,0.00029851616,0.0061646947],"study_design_scores_gemma":[0.0012717545,0.00030079688,0.73930025,0.00004183692,0.00007028496,0.00004377635,0.00005813489,0.00058754196,0.22027086,0.00027281154,0.037553098,0.00022884476],"about_ca_topic_score_codex":0.000008547301,"about_ca_topic_score_gemma":0.0000012745489,"teacher_disagreement_score":0.48032734,"about_ca_system_score_codex":0.0000917061,"about_ca_system_score_gemma":0.00015472845,"threshold_uncertainty_score":0.8309414},"labels":[],"label_agreement":null},{"id":"W1530359759","doi":"10.1080/15548627.2015.1034418","title":"Emerging role of autophagy in mediating widespread actions of ADIPOQ/adiponectin","year":2015,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; ATG5; Skeletal muscle; Biology; AMPK; Adiponectin; Cell biology; Endocrinology; Internal medicine; mTORC1; Flux (metallurgy); Signal transduction; Phosphorylation; Protein kinase A; PI3K/AKT/mTOR pathway; Insulin resistance; Insulin; Chemistry; Biochemistry; Apoptosis; Medicine","score_opus":0.031587328754071796,"score_gpt":0.3245923569750415,"score_spread":0.29300502822096974,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1530359759","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9863116,0.004276132,0.0000665944,0.00013504714,0.00031360213,0.00030057956,0.000015064949,0.00008917923,0.008492199],"genre_scores_gemma":[0.998342,0.00006841534,0.0008733339,0.00013641424,0.00013587541,0.00003245211,0.000023296048,0.00003824764,0.00034997743],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981917,0.00009099014,0.00067484035,0.00028008033,0.000422933,0.00033942438],"domain_scores_gemma":[0.99863654,0.00019286605,0.00030165908,0.00044499335,0.00018167426,0.0002422906],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043255335,0.00019769247,0.0005824089,0.00036750463,0.00003345239,0.0000048281677,0.00016111309,0.00014334435,0.00024200954],"category_scores_gemma":[0.0005230456,0.00019244723,0.00015694543,0.00058596715,0.00010617694,0.00016194484,0.000055883036,0.00023637952,0.000028989802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010178079,0.0019561222,0.047900517,0.00035500628,0.0006595963,0.0002456279,0.012909435,0.00084674364,0.82838964,0.008242542,0.00056079245,0.09691614],"study_design_scores_gemma":[0.0037624836,0.00045140044,0.09209197,0.00023395207,0.00016168694,0.000052163912,0.0016889701,0.0032808234,0.892726,0.0030269355,0.0023010643,0.00022257424],"about_ca_topic_score_codex":0.00053174543,"about_ca_topic_score_gemma":0.000029314915,"teacher_disagreement_score":0.09669357,"about_ca_system_score_codex":0.00010370585,"about_ca_system_score_gemma":0.00039316717,"threshold_uncertainty_score":0.78477705},"labels":[],"label_agreement":null},{"id":"W1530470155","doi":"10.1080/23723556.2015.1006077","title":"(-)-Oleocanthal rapidly and selectively induces cancer cell death via lysosomal membrane permeabilization","year":2015,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; University of Victoria","keywords":"Programmed cell death; Cancer cell; Apoptosis; Cell biology; Acid sphingomyelinase; Lysosome; Cell; Biology; Cell culture; Cell membrane; Cell growth; Cancer; Chemistry; Biochemistry; Ceramide; Enzyme","score_opus":0.023581045091963643,"score_gpt":0.3002333550707575,"score_spread":0.27665230997879386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1530470155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9795713,0.009931218,0.0035440892,0.00044703952,0.00022433509,0.00049663876,0.000006202393,0.00007871244,0.0057004928],"genre_scores_gemma":[0.9968063,0.00033050956,0.00076295045,0.0014303748,0.00018449966,0.00007629463,0.000060046525,0.000051700124,0.00029731874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983808,0.0002268146,0.0002647425,0.00046278993,0.000295979,0.00036889123],"domain_scores_gemma":[0.99898,0.000033276483,0.000120050536,0.00025334093,0.00021563274,0.00039770972],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021788581,0.0002506956,0.0004471057,0.00009215999,0.000078561636,0.000016104801,0.00010219904,0.0002905725,0.00021964053],"category_scores_gemma":[0.000036208436,0.00023274851,0.00009563547,0.00018222298,0.00013179626,0.000092571536,0.000054428285,0.00021078442,0.000023435237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004359981,0.00046308144,0.0035191195,0.0000607563,0.00015620713,0.00079485564,0.00078884733,0.000059828762,0.98817205,0.00021619257,0.000091013004,0.005242054],"study_design_scores_gemma":[0.00425464,0.0014061764,0.003450436,0.00002319022,0.0003584739,0.0001491152,0.0002472275,0.0014043153,0.9831841,0.00044495612,0.0048023043,0.00027507267],"about_ca_topic_score_codex":0.000355776,"about_ca_topic_score_gemma":0.000039413593,"teacher_disagreement_score":0.017235033,"about_ca_system_score_codex":0.00030976904,"about_ca_system_score_gemma":0.0007162801,"threshold_uncertainty_score":0.9491209},"labels":[],"label_agreement":null},{"id":"W1536668550","doi":"","title":"Abstract 12302: A Novel Role of Autophagy in the Regulation of Endothelial to Mesenchymal Transition","year":2014,"lang":"en","type":"article","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Autophagy; Umbilical vein; Cell biology; Mesenchymal stem cell; Gene silencing; Pathogenesis; Medicine; Cardiac fibrosis; Endothelium; Cytoskeleton; Endothelial stem cell; Fibrosis; Apoptosis; Biology; Pathology; Gene; Cell; Internal medicine; In vitro; Genetics","score_opus":0.01023126462321065,"score_gpt":0.26086537702631585,"score_spread":0.2506341124031052,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1536668550","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868019,0.000029366895,0.0019804172,0.0005111804,0.000024700257,0.0002851672,0.000012269271,0.000012774353,0.01034223],"genre_scores_gemma":[0.9988146,0.0000027860517,0.0005235138,0.00048212206,0.00008189404,0.000010304789,0.000011137997,0.0000066271245,0.0000670076],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99933237,0.00002335522,0.00023814802,0.000097406584,0.00021687926,0.00009181524],"domain_scores_gemma":[0.99961454,0.000063940504,0.000053813837,0.00019034502,0.000041655778,0.00003570014],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026131136,0.00006558421,0.0001634892,0.00008377702,0.000011732803,0.0000023333162,0.0000623481,0.000047311292,0.00029825806],"category_scores_gemma":[0.000027912027,0.000043235083,0.00006960746,0.00012478314,0.000027689443,0.00004187031,0.0000036276913,0.00005170847,0.000006366744],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037747924,0.00036887536,0.00019528056,0.000034971035,0.000018627328,7.6586093e-7,0.0022203259,0.00016078581,0.9802697,0.008126146,0.000033317658,0.008193771],"study_design_scores_gemma":[0.001878637,0.00029662088,0.5569442,0.000058747843,0.00002970733,0.0000064673263,0.000374927,0.002163116,0.43572217,0.0018782039,0.0005914577,0.000055758832],"about_ca_topic_score_codex":0.0001508327,"about_ca_topic_score_gemma":0.000017446993,"teacher_disagreement_score":0.55674887,"about_ca_system_score_codex":0.000010079734,"about_ca_system_score_gemma":0.000032212956,"threshold_uncertainty_score":0.32657164},"labels":[],"label_agreement":null},{"id":"W1551635375","doi":"10.4161/auto.27198","title":"Autophagy and SQSTM1 on the RHOA(d) again","year":2013,"lang":"fr","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Nautical Research Society","funders":"National Institute of General Medical Sciences; Agence de l'Environnement et de la Maîtrise de l'Energie; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Direction Régionale de l'Environnement, de l'Aménagement et du Logement PACA","keywords":"RHOA; Cell biology; Autophagy; Biology; Cytokinesis; Signal transduction; Midbody; Motility; BAG3; Crosstalk; Cell; Cell division; Apoptosis; Biochemistry","score_opus":0.014050492565586025,"score_gpt":0.2529798313731698,"score_spread":0.2389293388075838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1551635375","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8066706,0.096869916,0.00008650486,0.034776486,0.0039613987,0.0018379942,0.000050480583,0.0002668012,0.05547983],"genre_scores_gemma":[0.8597317,0.0034551367,0.00014309125,0.02151208,0.0020110642,0.00024081304,0.000021845854,0.000111088506,0.1127732],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99655,0.00038976496,0.0005881927,0.0007450484,0.0005654314,0.0011615591],"domain_scores_gemma":[0.9969632,0.0009097592,0.00019372185,0.0011623051,0.00013351961,0.00063749234],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0005316291,0.0006142823,0.00063736585,0.00014844914,0.00041030414,0.0001890563,0.00040329882,0.00041954042,0.022600818],"category_scores_gemma":[0.00027211523,0.00043412676,0.00027484042,0.00037276294,0.00075723336,0.00029974568,0.00015449978,0.0007732608,0.011493939],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017796273,0.0013698896,0.00058880635,0.0003889677,0.0011171398,0.0008840411,0.0023717207,0.00002704482,0.01133878,0.35365328,0.1964202,0.4316622],"study_design_scores_gemma":[0.0071788025,0.0026787587,0.2761251,0.0017170575,0.00087284565,0.00046683272,0.0013588719,0.013887726,0.08505631,0.054649696,0.55433786,0.0016701402],"about_ca_topic_score_codex":0.00046995844,"about_ca_topic_score_gemma":0.0000057209754,"teacher_disagreement_score":0.42999205,"about_ca_system_score_codex":0.00016495827,"about_ca_system_score_gemma":0.00025728863,"threshold_uncertainty_score":0.99981105},"labels":[],"label_agreement":null},{"id":"W155513443","doi":"10.1096/fasebj.21.6.a1344-d","title":"Effect of chronic treadmill running on apoptotic protein expression in soleus muscle of normotensive and hypertensive rats","year":2007,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Waterloo","funders":"Heart and Stroke Foundation of Canada","keywords":"Skeletal muscle; Internal medicine; Endocrinology; XIAP; Soleus muscle; Medicine; Apoptosis; sed; Muscle hypertrophy; DNA fragmentation; Myocyte; Caspase; Biology; Programmed cell death; Biochemistry","score_opus":0.00955177153082266,"score_gpt":0.26858369601827525,"score_spread":0.2590319244874526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W155513443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99737465,0.0018337932,0.000057350302,0.00008936194,0.00005739685,0.00039965284,0.0000017379917,0.0000058995192,0.00018013058],"genre_scores_gemma":[0.99954116,0.00009976807,0.000041805964,0.000118694064,0.00014224267,0.0000029254247,0.0000014397924,0.000014524098,0.00003744016],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990489,0.0001040944,0.0002925266,0.00010453273,0.00024076404,0.0002092067],"domain_scores_gemma":[0.9992113,0.00020091771,0.0002110702,0.00017179946,0.00009569876,0.000109213805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00066449045,0.00012655556,0.0003510254,0.00013807658,0.00006544265,0.000004654977,0.00006980046,0.00006071618,0.00002806087],"category_scores_gemma":[0.000115132854,0.00006984165,0.00008819587,0.000108579196,0.00010991457,0.000042307227,0.000019887671,0.0003102323,0.0000022932982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020339508,0.00009927055,0.0007050365,0.000081147475,0.000045561115,0.0002642944,0.0005123982,0.00003626063,0.9783381,0.0000069943353,0.000018463694,0.017858503],"study_design_scores_gemma":[0.0033816716,0.0032481488,0.033843745,0.0012677921,0.00007445806,0.00016672186,0.0002454374,0.00018099045,0.95745856,0.00006513966,0.000006827585,0.00006049299],"about_ca_topic_score_codex":0.000013223905,"about_ca_topic_score_gemma":0.000002043238,"teacher_disagreement_score":0.033138707,"about_ca_system_score_codex":0.00006091741,"about_ca_system_score_gemma":0.00007781,"threshold_uncertainty_score":0.28480598},"labels":[],"label_agreement":null},{"id":"W1561196439","doi":"10.1080/15548627.2015.1052207","title":"Disruption in the autophagic process underlies the sensory neuropathy in<i>dystonia musculorum</i>mice","year":2015,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; Department of Science and Technology, Ministry of Science and Technology, India","keywords":"Biology; Autophagy; Cell biology; Dynein; Neuroscience; Microtubule; Biochemistry","score_opus":0.042614179815723865,"score_gpt":0.3278832239014893,"score_spread":0.2852690440857654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1561196439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98773116,0.0026672038,0.000033217624,0.0039037336,0.00032321975,0.0007782039,0.0000051457014,0.00011269353,0.0044454127],"genre_scores_gemma":[0.99305135,0.00011512677,0.000023595236,0.005699985,0.00023214355,0.00012933444,0.000017503413,0.000038661987,0.00069230964],"study_design_codex":"qualitative","study_design_gemma":"observational","domain_scores_codex":[0.99781054,0.00038654506,0.00040488748,0.00038444952,0.0005559844,0.00045761978],"domain_scores_gemma":[0.9988644,0.00019088018,0.000112712645,0.0006215287,0.00008552103,0.00012491988],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008588003,0.00026457335,0.00031903342,0.00014821294,0.000107079315,0.000053738862,0.00037902416,0.00011944681,0.00004738946],"category_scores_gemma":[0.0001743669,0.00015132918,0.00011411001,0.00065071275,0.0001945682,0.00019978413,0.000046062454,0.00052078743,0.00016580646],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009506665,0.017285973,0.17793901,0.002673924,0.0010427185,0.030266564,0.42164105,0.010278779,0.06475345,0.07917881,0.011836848,0.1735962],"study_design_scores_gemma":[0.007379272,0.00073332095,0.9460699,0.00019527868,0.0001765226,0.0007654075,0.0116850585,0.006333293,0.005112537,0.012361567,0.008634788,0.0005530483],"about_ca_topic_score_codex":0.00013557404,"about_ca_topic_score_gemma":0.000074661904,"teacher_disagreement_score":0.7681309,"about_ca_system_score_codex":0.000114732095,"about_ca_system_score_gemma":0.000284443,"threshold_uncertainty_score":0.6171025},"labels":[],"label_agreement":null},{"id":"W1567840615","doi":"10.1073/pnas.1508815112","title":"Metformin increases degradation of phospholamban via autophagy in cardiomyocytes","year":2015,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Toronto General Hospital; University of Toronto; Ted Rogers Centre for Heart Research; University Health Network","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Government of Canada; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Bafilomycin; Phospholamban; Cell biology; Lysosome; Sequestosome 1; ATG5; Protein degradation; LAMP1; SERCA; Biology; Chemistry; Endoplasmic reticulum; Biochemistry; ATPase; Apoptosis","score_opus":0.055068429013215875,"score_gpt":0.329991044866526,"score_spread":0.2749226158533101,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1567840615","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950314,0.001017428,0.0000014940074,0.00041273533,0.000011817613,0.00018125489,0.0000072648218,0.000007817553,0.003328799],"genre_scores_gemma":[0.99855196,0.000046600882,0.0011013122,0.00014329074,0.00003637193,0.000008565829,3.973782e-7,0.0000033237568,0.000108196306],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99836415,0.0000063666225,0.000336216,0.00014313798,0.0010466422,0.000103464095],"domain_scores_gemma":[0.9992057,0.00007051459,0.00032963167,0.000009363982,0.00033173026,0.00005307129],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012556695,0.00007501219,0.00022499952,0.0002181916,0.000035648787,0.000004927683,0.00029603386,0.000061639235,0.000011099093],"category_scores_gemma":[0.0006362846,0.000048905233,0.00008045228,0.00079566805,0.00047107716,0.00034456854,0.000053992873,0.00009003231,6.862934e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052581157,0.00067972264,0.18406796,0.0003299083,0.00014070445,1.738047e-7,0.0008782279,0.00013825361,0.7452198,0.059439886,0.0010497919,0.007529741],"study_design_scores_gemma":[0.00058166723,0.00009764646,0.186503,0.0001094541,0.000026379685,0.000014667021,0.00022169026,0.00072922034,0.7867202,0.02487446,0.000075820295,0.000045778965],"about_ca_topic_score_codex":0.00007464388,"about_ca_topic_score_gemma":1.0319339e-7,"teacher_disagreement_score":0.041500404,"about_ca_system_score_codex":0.000050583334,"about_ca_system_score_gemma":0.0001176696,"threshold_uncertainty_score":0.19942975},"labels":[],"label_agreement":null},{"id":"W1574067699","doi":"10.1371/journal.pgen.1004409","title":"Aberrant Autolysosomal Regulation Is Linked to The Induction of Embryonic Senescence: Differential Roles of Beclin 1 and p53 in Vertebrate Spns1 Deficiency","year":2014,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; Fondation pour la Recherche Médicale; National Institute on Aging; National Institutes of Health; Glenn Foundation for Medical Research; Ellison Medical Foundation","keywords":"Autophagy; Senescence; Cell biology; Biology; Autophagosome; Zebrafish; Phenotype; Lysosome; DNA damage; ATG5; Genetics; Apoptosis; Gene; Biochemistry; DNA","score_opus":0.01779310019508089,"score_gpt":0.25643827829208515,"score_spread":0.23864517809700425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1574067699","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99805427,0.00062670064,0.00039671414,0.0005147524,0.00007736549,0.00027753614,0.000005831255,0.000009866047,0.000036977082],"genre_scores_gemma":[0.99941593,0.00015170072,0.00018355543,0.0001050182,0.000083776584,0.0000067619717,0.0000072623566,0.000010926756,0.000035053283],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991858,0.00005473701,0.0002576818,0.00015662005,0.00022449004,0.00012066909],"domain_scores_gemma":[0.99951077,0.000025624684,0.00009836852,0.0002449456,0.00006839882,0.00005189725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008844042,0.00009191738,0.00020378435,0.00008315312,0.000030681178,0.000005275161,0.000068561654,0.00007983445,0.000038475904],"category_scores_gemma":[0.000029051645,0.00006698461,0.00003861064,0.00015945947,0.00006549091,0.000018883953,0.000028167318,0.000079109865,0.0000036419578],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027384807,0.0004070126,0.059867833,0.00017069351,0.00005119094,9.420421e-7,0.0028430454,0.0002254708,0.9130833,0.00022030417,0.000026533327,0.022829827],"study_design_scores_gemma":[0.001066427,0.00033301045,0.5601198,0.00013425537,0.00012028517,0.000003229299,0.000107137515,0.064525,0.37279978,0.00067815604,0.00003216125,0.000080752514],"about_ca_topic_score_codex":0.0000052923588,"about_ca_topic_score_gemma":0.00001664863,"teacher_disagreement_score":0.5402835,"about_ca_system_score_codex":0.000012745144,"about_ca_system_score_gemma":0.000047320358,"threshold_uncertainty_score":0.27315533},"labels":[],"label_agreement":null},{"id":"W1574308332","doi":"10.1096/fasebj.29.1_supplement.978.5","title":"Repeated Induction of Autophagy or Mitophagy Protects C2C12 Cells from Subsequent Apoptotic Insults","year":2015,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Autophagy; Mitophagy; Cell biology; Apoptosis; Mitochondrion; Mitochondrial permeability transition pore; Programmed cell death; Chemistry; Biology; Biochemistry","score_opus":0.05187856056194769,"score_gpt":0.2875764266542993,"score_spread":0.2356978660923516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1574308332","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99660814,0.0011459114,0.00020886006,0.00039136782,0.00084811315,0.0004904531,0.000019851082,0.000054094966,0.00023321333],"genre_scores_gemma":[0.9973823,0.00014702918,0.00043562942,0.0002974418,0.0008763169,0.000012442041,0.000016914855,0.00003162871,0.0008003147],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99818647,0.0002345432,0.00052027445,0.00019375757,0.0005799755,0.0002850042],"domain_scores_gemma":[0.99841386,0.000065249056,0.000396487,0.0004440316,0.00029890495,0.0003814695],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054786494,0.00019030082,0.00036838048,0.0001226949,0.00012244508,0.00003131177,0.00022126125,0.00012860938,0.00038816896],"category_scores_gemma":[0.00018216134,0.00011114813,0.00015214126,0.0002932438,0.00014696675,0.00013997026,0.0000364761,0.0005320032,0.00007675454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033641823,0.000494882,0.00038393275,0.000033447126,0.00046449152,0.0005978681,0.0023497702,0.00013979014,0.9834905,0.000025677187,0.0011577463,0.0074976655],"study_design_scores_gemma":[0.0045873057,0.0008528596,0.008279556,0.00018809989,0.00017249236,0.0006153008,0.0007073963,0.00023578678,0.9828914,0.001037782,0.00030234893,0.00012969106],"about_ca_topic_score_codex":0.00014167359,"about_ca_topic_score_gemma":0.0000059795975,"teacher_disagreement_score":0.007895624,"about_ca_system_score_codex":0.00016493736,"about_ca_system_score_gemma":0.00060731446,"threshold_uncertainty_score":0.45324895},"labels":[],"label_agreement":null},{"id":"W1583701773","doi":"10.1111/j.1471-4159.2012.07676.x","title":"Hypoxia regulation of ATP13A2 (PARK9) gene transcription","year":2012,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; China Scholarship Council; Canada Research Chairs; University of Pittsburgh","keywords":"Gene; Transcription factor; Biology; Genetics; Regulation of gene expression; Exon; Gene expression; Transcription (linguistics); Promoter; Cell biology","score_opus":0.020333392098727768,"score_gpt":0.2684995356761089,"score_spread":0.24816614357738115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1583701773","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969352,0.00161331,0.00022485605,0.00017829065,0.00017912935,0.00003752431,0.0000024412188,0.000006798665,0.00082243717],"genre_scores_gemma":[0.9983439,0.00016982875,0.000398081,0.00015191126,0.0006715099,5.110204e-7,0.0000044773915,0.000011646317,0.0002481535],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922687,0.000015830155,0.0003406954,0.00005075412,0.00025362824,0.00011225298],"domain_scores_gemma":[0.9992847,0.000018371116,0.00028678804,0.00012830248,0.00013112473,0.00015075086],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012418629,0.000074769254,0.00019213282,0.00003893645,0.000016271215,0.0000028253594,0.000057551522,0.0000638468,0.00016682503],"category_scores_gemma":[0.00004178032,0.00006302201,0.00016211193,0.00007057593,0.000029894056,0.00011635029,0.0000041654926,0.0001411318,0.0000026854577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032689128,0.00022885339,0.0025110375,0.00007991647,0.00005363694,0.000013655913,0.000096783435,0.000004478791,0.9952269,0.000008061148,0.0006218249,0.00082796236],"study_design_scores_gemma":[0.0008356628,0.00009591202,0.25251314,0.000054413864,0.00012391339,0.0005426099,0.000022709355,0.000012433617,0.74459594,0.00006829647,0.0010961719,0.00003877969],"about_ca_topic_score_codex":3.018262e-7,"about_ca_topic_score_gemma":8.248329e-9,"teacher_disagreement_score":0.25063094,"about_ca_system_score_codex":0.00002255021,"about_ca_system_score_gemma":0.000051201427,"threshold_uncertainty_score":0.2569963},"labels":[],"label_agreement":null},{"id":"W1586603626","doi":"10.1002/9780470988855.ch3","title":"Membrane Dynamics and Regulation of Subcellular Changes During Senescence","year":2007,"lang":"en","type":"book-chapter","venue":"Blackwell Publishing Ltd eBooks","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Senescence; Autophagy; Membrane; Proteolysis; Cell biology; Biology; Metabolism; Biochemistry; Chemistry; Enzyme","score_opus":0.020844550025271844,"score_gpt":0.23594574024987403,"score_spread":0.21510119022460217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1586603626","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.095554695,0.0025020102,0.0003001287,0.00042773006,0.00037549654,0.0010171343,0.00012129391,0.00025279043,0.89944875],"genre_scores_gemma":[0.37310073,0.0004926993,0.00027479694,0.00030572584,0.0006874407,0.000006121794,0.0003938389,0.00017194543,0.62456673],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99797523,0.000019913146,0.00049681537,0.0005374466,0.00062358,0.00034701213],"domain_scores_gemma":[0.99825144,0.000081587714,0.00047946352,0.0006439212,0.000283432,0.00026016802],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047919678,0.000426703,0.0006716752,0.0004764002,0.00009914644,0.00015917992,0.00019890303,0.0006967344,0.00019370875],"category_scores_gemma":[0.000058354857,0.00042858024,0.0001653001,0.000036003585,0.00028082792,0.0002248907,0.00012141267,0.0005845182,0.000007361295],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040940144,0.00029903156,0.0017289354,0.0151792625,0.0026244298,0.0015455274,0.0032535684,0.000025651509,0.12980361,0.71942466,0.0027307153,0.11929057],"study_design_scores_gemma":[0.022514941,0.0019914447,0.033436894,0.022130394,0.005698189,0.0018557531,0.00072022836,0.005348977,0.68531877,0.05463388,0.15924855,0.0071019563],"about_ca_topic_score_codex":0.00004739188,"about_ca_topic_score_gemma":0.00008619843,"teacher_disagreement_score":0.6647908,"about_ca_system_score_codex":0.00013839401,"about_ca_system_score_gemma":0.00014658233,"threshold_uncertainty_score":0.9998166},"labels":[],"label_agreement":null},{"id":"W1590762591","doi":"10.1007/s12630-009-9220-9","title":"Vacuolar ATPase-mediated sequestration of local anesthetics in swollen macroautophagosomes","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Anesthesia/Journal canadien d anesthésie","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Vacuole; Cell biology; Bafilomycin; Autophagy; Biology; V-ATPase; Nocodazole; Lysosome; LAMP1; Chemistry; Biochemistry; Cytoplasm; Cell; ATPase; Cytoskeleton; Apoptosis","score_opus":0.008558074720348733,"score_gpt":0.23309980354933504,"score_spread":0.22454172882898632,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1590762591","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994698,0.0013797389,0.000027419605,0.0030053174,0.0003372029,0.00023305573,0.000010813351,0.000010937791,0.0002975114],"genre_scores_gemma":[0.99837977,0.00015348088,0.000478905,0.00021633251,0.0005083884,0.0000028523093,0.000018094048,0.00006953445,0.00017263183],"study_design_codex":"case_report","study_design_gemma":"case_report","domain_scores_codex":[0.9967305,0.00015141747,0.0013874235,0.00023937807,0.00064755254,0.0008437023],"domain_scores_gemma":[0.99515855,0.00010619884,0.0008558114,0.00036840537,0.00085536187,0.0026556987],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013111567,0.0003851053,0.00093096565,0.0013954116,0.00019225254,0.000090018715,0.00050530484,0.000419816,0.00053625996],"category_scores_gemma":[0.00020454623,0.00034350925,0.00038194668,0.000697383,0.0004919116,0.00040982827,0.0000059531108,0.0016391715,0.000015792642],"study_design_candidate":"case_report","study_design_consensus":"case_report","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00059069373,0.00023579941,0.052623816,0.000119150376,0.00020352728,0.9316235,0.0016753738,0.00020793702,0.0036467698,0.0011498182,0.000976972,0.0069466243],"study_design_scores_gemma":[0.002855827,0.0014446679,0.08459949,0.00032146723,0.00018074259,0.89994895,0.00080794416,0.00014178257,0.003834302,0.0007921306,0.004723158,0.00034953794],"about_ca_topic_score_codex":0.004662067,"about_ca_topic_score_gemma":0.012344637,"teacher_disagreement_score":0.03197567,"about_ca_system_score_codex":0.00048479572,"about_ca_system_score_gemma":0.008943035,"threshold_uncertainty_score":0.9999017},"labels":[],"label_agreement":null},{"id":"W1606263203","doi":"10.1096/fasebj.29.1_supplement.821.3","title":"Parkin and its Role in Skeletal Muscle Function","year":2015,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Parkin; Function (biology); Skeletal muscle; Business; Medicine; Cell biology; Anatomy; Biology; Internal medicine; Disease","score_opus":0.022370134688354942,"score_gpt":0.265090921452824,"score_spread":0.24272078676446904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1606263203","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915557,0.0058443816,0.00003627915,0.0006477964,0.00015140879,0.00007550467,0.0000010429029,0.000010769264,0.0016771168],"genre_scores_gemma":[0.9985711,0.00015593815,0.000011800108,0.00052582595,0.00036324342,0.0000022623726,0.0000015948452,0.000007492294,0.00036074524],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999492,0.000055862565,0.00011128992,0.000059831167,0.00015740909,0.00012359653],"domain_scores_gemma":[0.9996715,0.00001651064,0.00004115704,0.00007584542,0.000036134916,0.0001588493],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003626741,0.000058226677,0.00008998259,0.00004625726,0.000055535726,0.000017418748,0.000041266292,0.000030138686,0.00012259683],"category_scores_gemma":[0.00003052206,0.000035314322,0.000033037522,0.00006910181,0.000022667422,0.00007757943,0.000012605224,0.00021585978,0.000040839557],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034017016,0.0014030383,0.0715004,0.000068593276,0.00075949123,0.0018033611,0.011619612,0.00028830778,0.4648738,0.0031855535,0.01054095,0.4305552],"study_design_scores_gemma":[0.015822973,0.0019391684,0.86781675,0.00023533287,0.00041793814,0.003007141,0.0047936207,0.0051567154,0.03961312,0.020712648,0.040097512,0.00038710365],"about_ca_topic_score_codex":0.000006018071,"about_ca_topic_score_gemma":0.0000030030928,"teacher_disagreement_score":0.7963163,"about_ca_system_score_codex":0.00002957478,"about_ca_system_score_gemma":0.00007283881,"threshold_uncertainty_score":0.14400762},"labels":[],"label_agreement":null},{"id":"W1638800501","doi":"10.1080/15548627.2015.1067362","title":"Cross-cancer profiling of molecular alterations within the human autophagy interaction network","year":2015,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":129,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Burnaby Hospital; BC Cancer Agency; Simon Fraser University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Autophagy; Carcinogenesis; Cancer research; Cancer; Lung cancer; Gene; Genetics; Pathology; Medicine","score_opus":0.04223935526895316,"score_gpt":0.38206710366030094,"score_spread":0.3398277483913478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1638800501","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99194837,0.0022151677,0.00096435694,0.00031738175,0.00081914087,0.0005099023,0.000009188211,0.00011753529,0.003098942],"genre_scores_gemma":[0.9960726,0.000017882325,0.00081207306,0.0011173845,0.0005733587,0.0001234475,0.000048363985,0.000038403075,0.0011965191],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852663,0.0000977272,0.00048263135,0.00027368695,0.0003558127,0.0002634876],"domain_scores_gemma":[0.9987415,0.00004930483,0.00025848646,0.00051091454,0.00027833454,0.00016147982],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038382856,0.00018921237,0.00030175256,0.00006343686,0.00017354662,0.000049176488,0.00017654465,0.000101611746,0.00029145114],"category_scores_gemma":[0.00006416272,0.0001363084,0.00015436985,0.00028563748,0.00016859286,0.00018212193,0.00005420465,0.00026967068,0.000038650218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012199865,0.0015966309,0.04606778,0.00037138292,0.0018734605,0.0005003499,0.0064234827,0.08366608,0.67741054,0.16355598,0.005531381,0.011782926],"study_design_scores_gemma":[0.002915482,0.0004550534,0.033856645,0.00020005352,0.0002844045,0.00006859469,0.00023043166,0.009488205,0.9394937,0.010708732,0.002015464,0.0002832441],"about_ca_topic_score_codex":0.00009355261,"about_ca_topic_score_gemma":0.0000073321903,"teacher_disagreement_score":0.2620831,"about_ca_system_score_codex":0.000089359106,"about_ca_system_score_gemma":0.0002812502,"threshold_uncertainty_score":0.55584955},"labels":[],"label_agreement":null},{"id":"W1646601758","doi":"10.1007/s10522-015-9598-4","title":"Muscle-specificity of age-related changes in markers of autophagy and sphingolipid metabolism","year":2015,"lang":"en","type":"article","venue":"Biogerontology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Heritage College","funders":"","keywords":"Soleus muscle; Autophagy; Endocrinology; Internal medicine; Endoplasmic reticulum; Sphingolipid; Biology; Sarcopenia; Gastrocnemius muscle; Ageing; Contractility; Skeletal muscle; Chemistry; Cell biology; Biochemistry; Medicine","score_opus":0.0359746255932324,"score_gpt":0.28522559824959404,"score_spread":0.24925097265636165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1646601758","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883346,0.0085356,0.000010690058,0.00041587016,0.00023810705,0.00021182791,0.000014331999,0.000024146635,0.0022148443],"genre_scores_gemma":[0.99897426,0.0003775847,0.0002956964,0.00012930373,0.00005036909,0.000008366809,0.000013476063,0.0000121826915,0.00013873806],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99907523,0.00009221,0.00031117644,0.00019968749,0.00012662825,0.0001950426],"domain_scores_gemma":[0.99937683,0.000050252802,0.000146486,0.00023157307,0.000063666164,0.00013117025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026427442,0.0001222845,0.0005504064,0.00018736642,0.00000920041,0.000001569008,0.00007449596,0.00017643445,0.00011481357],"category_scores_gemma":[0.000079585865,0.00010598976,0.000054209973,0.00015828096,0.00030181388,0.00003155482,0.000034920737,0.00009371303,0.0000031519207],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015125214,0.0046994044,0.17968306,0.0013263178,0.0022927525,0.0019520407,0.022339135,0.000014763041,0.52769315,0.050448306,0.0058798576,0.188546],"study_design_scores_gemma":[0.0052516377,0.00056518463,0.9578675,0.00006225606,0.00012321382,0.0000467124,0.00055172545,0.00011071716,0.027581682,0.0013292602,0.0063658063,0.00014429183],"about_ca_topic_score_codex":0.00052771106,"about_ca_topic_score_gemma":0.0002720077,"teacher_disagreement_score":0.7781845,"about_ca_system_score_codex":0.000025386724,"about_ca_system_score_gemma":0.00006712329,"threshold_uncertainty_score":0.4322137},"labels":[],"label_agreement":null},{"id":"W1655274072","doi":"10.1080/15548627.2015.1055440","title":"Feedback regulation between autophagy and PKA","year":2015,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; PROTEO","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Biology; BAG3; Regulator; Cell biology; Protein kinase A; Autophagy-related protein 13; Acetylation; Post-translational regulation; Gene; Biochemistry; Kinase; Phosphorylation; Mitogen-activated protein kinase kinase","score_opus":0.04243663040986197,"score_gpt":0.3036397631987115,"score_spread":0.26120313278884955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1655274072","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98486805,0.002394026,0.0003815814,0.0007999491,0.00030201772,0.00034538,0.00001095225,0.00027516106,0.010622879],"genre_scores_gemma":[0.9915882,0.00004774832,0.0009113379,0.00082577905,0.00080658786,0.000017455592,0.00007398836,0.000040284227,0.005688666],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9986462,0.000055169126,0.00029331085,0.0003495768,0.00034722526,0.000308504],"domain_scores_gemma":[0.9988421,0.000057674013,0.00009100371,0.00040352653,0.00011609091,0.00048958],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024263762,0.00020718979,0.00037260982,0.00011869862,0.00007667428,0.00003366966,0.00008851625,0.00016410716,0.00028919487],"category_scores_gemma":[0.000077425975,0.00018459812,0.00008168272,0.00020675713,0.000119745,0.0001817638,0.000055523455,0.00015838146,0.00031626565],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022936044,0.0014925913,0.20922759,0.0006595071,0.002130405,0.00091454695,0.008158661,0.000078304016,0.040950757,0.042929888,0.09751198,0.5936522],"study_design_scores_gemma":[0.0050635743,0.0005383015,0.89569736,0.00006682802,0.00023299787,0.00011681482,0.000109071654,0.00067759195,0.041302696,0.011385209,0.044486962,0.00032258476],"about_ca_topic_score_codex":0.00003777065,"about_ca_topic_score_gemma":0.0000011976649,"teacher_disagreement_score":0.6864698,"about_ca_system_score_codex":0.000078079516,"about_ca_system_score_gemma":0.00017282892,"threshold_uncertainty_score":0.7527693},"labels":[],"label_agreement":null},{"id":"W1678674047","doi":"10.1097/ppo.0000000000000131","title":"Mechanisms of Drug Resistance Related to the Microenvironment of Solid Tumors and Possible Strategies to Inhibit Them","year":2015,"lang":"en","type":"review","venue":"The Cancer Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Drug resistance; Hypoxia (environmental); Tumor microenvironment; Drug; Cancer research; Distribution (mathematics); Blood flow; Pharmacology; Autophagy; Biology; Medicine; Chemistry; Internal medicine; Tumor cells; Apoptosis","score_opus":0.03381782665456346,"score_gpt":0.3416463315995893,"score_spread":0.30782850494502584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1678674047","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0038572832,0.99335974,0.00007761023,0.0012938009,0.00013744636,0.0007701364,0.00009732679,0.000006208275,0.0004004475],"genre_scores_gemma":[0.0048381807,0.99207824,0.00014066981,0.00026963075,0.00010681467,0.000044136403,0.0000032465073,0.000040961568,0.0024781104],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998342,0.00017461993,0.00067581295,0.00018360038,0.00040560128,0.00021837835],"domain_scores_gemma":[0.99862075,0.00004872127,0.0005869098,0.0004468541,0.00008840411,0.000208348],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008827422,0.00024911118,0.0010501471,0.00007412693,0.00010325961,0.000022628516,0.00037704443,0.00007040639,0.00019626458],"category_scores_gemma":[0.000014946188,0.00011652413,0.00021709866,0.0002147553,0.00011151147,0.000039753453,0.000092289025,0.00045799295,0.000012781396],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002239965,0.00051346945,0.000015739999,0.01843582,0.0061426987,0.00033749576,0.025190176,0.00030155695,0.0036032107,0.009620718,0.0709725,0.8626267],"study_design_scores_gemma":[0.0015252944,0.00040542352,0.00013844456,0.047640007,0.0031883474,0.0007441807,0.0035503288,0.0000020562195,0.0048661265,0.029890792,0.90756536,0.00048364323],"about_ca_topic_score_codex":0.0000120282,"about_ca_topic_score_gemma":0.000009871823,"teacher_disagreement_score":0.862143,"about_ca_system_score_codex":0.00017361795,"about_ca_system_score_gemma":0.0007742279,"threshold_uncertainty_score":0.4751716},"labels":[],"label_agreement":null},{"id":"W1706227909","doi":"10.1080/15548627.2015.1063764","title":"Disruption of the ribosomal P complex leads to stress-induced autophagy","year":2015,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pediatric Oncology Group","funders":"","keywords":"Autophagy; Unfolded protein response; Cell biology; Biology; ATF6; Endoplasmic reticulum; ATF4; Programmed cell death; Apoptosis; Signal transduction; Reactive oxygen species; Biochemistry","score_opus":0.06376668750139863,"score_gpt":0.3362329540428087,"score_spread":0.27246626654141004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1706227909","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917972,0.00032915178,0.00010511198,0.0012038056,0.00056443637,0.00060129585,0.000044726126,0.00012911767,0.00522512],"genre_scores_gemma":[0.9959608,0.000007479505,0.0003186996,0.0016923111,0.0003121666,0.000036254478,0.000034015127,0.000039186863,0.0015991026],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998225,0.00010039617,0.00040148583,0.0003252424,0.00058716006,0.00036073505],"domain_scores_gemma":[0.99842525,0.00004495141,0.00014605862,0.00079130713,0.0002015509,0.00039091],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018414443,0.00022952473,0.00041436462,0.00008422683,0.00008559823,0.000017234144,0.00031251612,0.0001281764,0.0004145989],"category_scores_gemma":[0.00014772038,0.00016144202,0.00021334489,0.00034378582,0.000103531595,0.00009667505,0.00013324089,0.00018968391,0.00021548478],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001287539,0.0018931911,0.044352293,0.00023053618,0.0004193152,0.0002154684,0.0039659617,0.0002494684,0.8920702,0.01462238,0.01132499,0.029368669],"study_design_scores_gemma":[0.002375256,0.00058392365,0.60931754,0.00009426919,0.00011689683,0.000045429075,0.000119100376,0.0005317136,0.38153663,0.0006100167,0.004476136,0.00019308733],"about_ca_topic_score_codex":0.00014689952,"about_ca_topic_score_gemma":0.000018175328,"teacher_disagreement_score":0.56496525,"about_ca_system_score_codex":0.000114219576,"about_ca_system_score_gemma":0.0002938578,"threshold_uncertainty_score":0.65834147},"labels":[],"label_agreement":null},{"id":"W1818029223","doi":"10.1080/15548627.2015.1056968","title":"Upregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells","year":2015,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Downregulation and upregulation; Cell biology; Biology; Apoptosis; Extracellular matrix; Biochemistry","score_opus":0.023205446531897222,"score_gpt":0.28180549978827507,"score_spread":0.25860005325637786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1818029223","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98873717,0.0045238864,0.0017528101,0.0012847782,0.00077885616,0.00238902,0.0003711445,0.000069523885,0.000092814225],"genre_scores_gemma":[0.9977025,0.000024017254,0.0005338545,0.00031724322,0.00019306326,0.00011065195,0.00005729834,0.000063254265,0.0009981402],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9957319,0.00054331444,0.001360365,0.0005669579,0.0012688778,0.00052858726],"domain_scores_gemma":[0.9958621,0.00076127355,0.001002438,0.0015273325,0.000585894,0.00026092434],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011615431,0.0004960475,0.00096452096,0.0001091046,0.00016786947,0.00003699559,0.0010480598,0.00028792667,0.00019729149],"category_scores_gemma":[0.0003398982,0.00027699716,0.00049243023,0.0005561099,0.00041494623,0.000119233715,0.00033158247,0.0004407745,0.00003539076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006600128,0.0007740513,0.0011693978,0.00007573136,0.0005394567,0.00000575833,0.0018012928,0.0002251465,0.9896657,0.0010532902,0.0010447591,0.0029854367],"study_design_scores_gemma":[0.0033636861,0.0006118451,0.032395024,0.00021741746,0.00066433905,0.000007910507,0.00044955217,0.0014356179,0.9582781,0.0016800236,0.00066914107,0.00022733658],"about_ca_topic_score_codex":0.0011587593,"about_ca_topic_score_gemma":0.000013920641,"teacher_disagreement_score":0.03138756,"about_ca_system_score_codex":0.00018544233,"about_ca_system_score_gemma":0.00055175036,"threshold_uncertainty_score":0.99996823},"labels":[],"label_agreement":null},{"id":"W1834684878","doi":"10.1038/ncb3206","title":"Intestinal inhibition of Atg7 prevents tumour initiation through a microbiome-influenced immune response and suppresses tumour growth","year":2015,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":183,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer; Ligue Contre le Cancer","keywords":"Autophagy; Immune system; Intestinal epithelium; Biology; Cancer research; Epithelium; Colorectal cancer; Intestinal mucosa; Microbiome; Cell biology; Immunology; Cancer; Medicine; Apoptosis; Internal medicine; Bioinformatics","score_opus":0.01316085304656957,"score_gpt":0.2951098093244872,"score_spread":0.28194895627791766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1834684878","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936322,0.0049795015,0.00006001152,0.00039917947,0.00015259931,0.00029205135,0.000041541185,0.000039392173,0.0004035186],"genre_scores_gemma":[0.9982589,0.00012696441,0.00068170537,0.00055684085,0.00008093233,0.000013283287,0.00020375058,0.000014598523,0.0000630127],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989809,0.00022403532,0.00028166376,0.00024389522,0.00008934082,0.0001801791],"domain_scores_gemma":[0.99919283,0.00014647476,0.00018430519,0.0001365615,0.0002546023,0.00008521991],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028495453,0.00015259275,0.0002910872,0.00011572673,0.000032610395,0.0000054496513,0.00006805961,0.00033867947,0.000032283522],"category_scores_gemma":[0.00044116518,0.00012410518,0.00005707968,0.00018382198,0.00015648495,0.000097220756,0.00005245628,0.00033411788,0.000009366624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032293906,0.00018436153,0.0028573093,0.00009338703,0.000027405933,0.000037806807,0.00045851932,3.7992635e-7,0.9925339,0.00017537748,0.00033194956,0.00007019666],"study_design_scores_gemma":[0.0028333354,0.00097259943,0.061524723,0.00013589235,0.00006266463,0.00007867525,0.00010616862,0.0000060486495,0.93100506,0.0027983019,0.0003673329,0.00010922581],"about_ca_topic_score_codex":0.000028008253,"about_ca_topic_score_gemma":9.468132e-7,"teacher_disagreement_score":0.061528884,"about_ca_system_score_codex":0.000045888093,"about_ca_system_score_gemma":0.00016334749,"threshold_uncertainty_score":0.50608623},"labels":[],"label_agreement":null},{"id":"W1840395037","doi":"10.1080/15548627.2015.1034408","title":"Deubiquitinating enzymes regulate PARK2-mediated mitophagy","year":2015,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":215,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Parkin; Deubiquitinating enzyme; Ubiquitin; Mitochondrion; Cell biology; PINK1; Biology; Autophagy; Biochemistry; Apoptosis; Gene; Medicine; Parkinson's disease","score_opus":0.04269411015436764,"score_gpt":0.30377817849563543,"score_spread":0.2610840683412678,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1840395037","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9688368,0.0065530916,0.0001896165,0.00088893075,0.00060440163,0.00044980092,0.000015856309,0.0006140286,0.021847513],"genre_scores_gemma":[0.9891427,0.0000675798,0.0013242635,0.0027115084,0.0005965242,0.00005238355,0.00010694469,0.00006893852,0.005929153],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979534,0.00009529999,0.00043681962,0.00043393823,0.0005297992,0.00055073196],"domain_scores_gemma":[0.99829406,0.00012842985,0.0001520358,0.0005616619,0.00023126608,0.00063255976],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00035424563,0.00029124133,0.00046612154,0.00015788393,0.00010069875,0.000038087703,0.00018598321,0.0001860626,0.0005787718],"category_scores_gemma":[0.000396131,0.0002571994,0.00017515839,0.00036399052,0.00012717705,0.000177728,0.000075044445,0.00024464613,0.0007795978],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0066576554,0.004928406,0.041915677,0.0012705082,0.004469136,0.01919334,0.016124912,0.00029606302,0.22842248,0.09064084,0.2908428,0.2952382],"study_design_scores_gemma":[0.01590968,0.0015866832,0.08579364,0.00032772383,0.0003554773,0.0007818357,0.000901492,0.0048959604,0.7547976,0.0073707215,0.126074,0.0012052145],"about_ca_topic_score_codex":0.000048431095,"about_ca_topic_score_gemma":0.0000023280206,"teacher_disagreement_score":0.5263751,"about_ca_system_score_codex":0.00011466249,"about_ca_system_score_gemma":0.00043293036,"threshold_uncertainty_score":0.9999984},"labels":[],"label_agreement":null},{"id":"W1844860071","doi":"10.1101/pdb.prot086256","title":"Monitoring Autophagic Flux by Using Lysosomal Inhibitors and Western Blotting of Endogenous MAP1LC3B","year":2015,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Flux (metallurgy); Endogeny; Lysosome; Blot; Drug; Chemistry; Cell biology; Pharmacology; Biochemistry; Biology; Enzyme; Apoptosis","score_opus":0.06894107139366758,"score_gpt":0.3213398820380909,"score_spread":0.2523988106444233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1844860071","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9750546,0.0011420705,0.00008750515,0.000024021376,0.00010670618,0.023307782,0.000006309915,0.0001328615,0.00013811553],"genre_scores_gemma":[0.99062353,0.000005127232,0.001214472,0.000045520184,0.00040230868,0.0075606355,5.193507e-7,0.00006175194,0.00008612168],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99839103,0.00005356407,0.00045044452,0.00033912165,0.00039416444,0.00037166243],"domain_scores_gemma":[0.99887884,0.000039074795,0.00022426627,0.00037127818,0.00012864395,0.00035791955],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032982507,0.00023743714,0.0004497622,0.00010722876,0.0000905924,0.000046644782,0.0001249556,0.00012143759,0.0000116838355],"category_scores_gemma":[0.00007352463,0.00023250224,0.00008419832,0.00015156875,0.00009141022,0.0001542681,0.0001041997,0.00019338663,0.000008490654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016545734,0.00021176602,0.18149528,0.0003318782,0.00008092974,0.00010415967,0.00019611456,0.000009649024,0.8167539,0.0000617543,0.00001573828,0.0005733436],"study_design_scores_gemma":[0.003419153,0.0004320029,0.01327476,0.0011822156,0.000080536076,0.000018406285,0.000050705534,0.00027575644,0.9790833,0.000012599385,0.0019409371,0.00022965512],"about_ca_topic_score_codex":0.00005930902,"about_ca_topic_score_gemma":1.878565e-7,"teacher_disagreement_score":0.16822052,"about_ca_system_score_codex":0.00012267809,"about_ca_system_score_gemma":0.00022619698,"threshold_uncertainty_score":0.9481166},"labels":[],"label_agreement":null},{"id":"W1856533655","doi":"10.1111/j.1749-6632.2010.05778.x","title":"Role of BNIP3 in proliferation and hypoxia‐induced autophagy: implications for personalized cancer therapies","year":2010,"lang":"en","type":"article","venue":"Annals of the New York Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Autophagy; Programmed cell death; Apoptosis; Cell biology; Hypoxia (environmental); Biology; Cancer research; Cell; Cell cycle; Cancer cell; Cell growth; Cancer; Chemistry; Genetics","score_opus":0.08920514588437709,"score_gpt":0.3902855693840339,"score_spread":0.3010804234996568,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1856533655","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9663594,0.0046751113,0.0000033576623,0.028344437,0.00002830244,0.0004559949,0.000017261718,0.000006135042,0.00011004664],"genre_scores_gemma":[0.99801475,0.00041269467,0.0004088083,0.00088339887,0.00007428784,0.000038149123,4.70947e-7,0.0000046842983,0.00016274051],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99926186,0.000022315662,0.0002504032,0.00015379644,0.0001800562,0.00013157834],"domain_scores_gemma":[0.99948937,0.000099260295,0.00022569177,0.00007771637,0.000053857053,0.000054126158],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004100273,0.00007586992,0.00021652921,0.00008535402,0.000082619044,0.000006180281,0.00022440312,0.000082732906,0.00002291035],"category_scores_gemma":[0.00007862784,0.000047754627,0.00008298872,0.00028411835,0.00046659628,0.00010000723,0.000020600888,0.00010614629,1.3019707e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000115441995,0.000072145376,0.017885681,0.000034026965,0.00003666692,6.1533947e-9,0.0015100923,0.000005265656,0.9433819,0.019617118,0.00035008407,0.016991556],"study_design_scores_gemma":[0.00051775837,0.000097594944,0.42663863,0.00006815617,0.000021171121,0.0000011976831,0.00019261561,0.00013369709,0.5354277,0.03593951,0.0009194564,0.000042536576],"about_ca_topic_score_codex":0.00010592118,"about_ca_topic_score_gemma":0.000014832658,"teacher_disagreement_score":0.40875295,"about_ca_system_score_codex":0.0000026253626,"about_ca_system_score_gemma":0.00018943606,"threshold_uncertainty_score":0.19473772},"labels":[],"label_agreement":null},{"id":"W1867840951","doi":"10.1161/circresaha.115.307023","title":"Disruption of RIP1-FADD Complexes by MicroRNA-103/107 Provokes Necrotic Cardiac Cell Death","year":2015,"lang":"en","type":"letter","venue":"Circulation Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"FADD; Medicine; Biomedical sciences; Programmed cell death; Pathophysiology; Apoptosis; Heart failure; Gerontology; Internal medicine; Pathology; Biology; Caspase","score_opus":0.10306110274624607,"score_gpt":0.3852731842913473,"score_spread":0.28221208154510125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1867840951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8764482,0.014085179,0.00030806626,0.08451798,0.00066450256,0.0056343223,0.00085305446,0.0002072309,0.01728147],"genre_scores_gemma":[0.9597624,0.00037238948,0.00012597187,0.017992152,0.0027127604,0.0002244398,0.008021836,0.00017978119,0.01060829],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9957925,0.00060494745,0.00052597665,0.0005807227,0.0018643464,0.00063147745],"domain_scores_gemma":[0.9972039,0.00026145965,0.00022163356,0.0008836494,0.0012104403,0.00021891267],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009838647,0.00031136075,0.00074001146,0.0005150798,0.00016065504,0.000068325506,0.0002860712,0.0007175161,0.0003417928],"category_scores_gemma":[0.00013372247,0.00028786686,0.00029592254,0.00045372793,0.0003105168,0.00011793981,0.000081188635,0.0016694684,0.00023345959],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010814455,0.00019383636,0.011677393,0.0012402717,0.00021086045,0.000066805194,0.0002867351,0.000016344744,0.046259016,0.000029352692,0.9391804,0.00073085533],"study_design_scores_gemma":[0.0031646404,0.0005940641,0.06453041,0.00073647284,0.0004372694,0.000023568975,0.00023166418,0.0007683052,0.017544443,0.0021146017,0.90910995,0.0007446174],"about_ca_topic_score_codex":0.0003982055,"about_ca_topic_score_gemma":0.0000014853492,"teacher_disagreement_score":0.08331418,"about_ca_system_score_codex":0.00036652308,"about_ca_system_score_gemma":0.00066587667,"threshold_uncertainty_score":0.9999573},"labels":[],"label_agreement":null},{"id":"W1869269119","doi":"10.1101/pdb.top070391","title":"Techniques for the Detection of Autophagy in Primary Mammalian Cells","year":2015,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; BC Cancer Agency","funders":"Biotechnology and Biological Sciences Research Council; National Institute for Health and Care Research; Lady Tata Memorial Trust; Natural Sciences and Engineering Research Council of Canada; Wellcome Trust","keywords":"Autophagy; Mitophagy; Cell biology; Cytoplasm; Flow cytometry; Endoplasmic reticulum; Organelle; Programmed cell death; Mitochondrion; Chemistry; Blot; Unfolded protein response; Biology; Apoptosis; Biochemistry; Molecular biology","score_opus":0.031891966290848915,"score_gpt":0.31027031604035854,"score_spread":0.27837834974950965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1869269119","genre_codex":"protocol","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.40629828,0.00122814,0.028859466,0.0006194228,0.00032483708,0.56037015,0.000027900807,0.0006338488,0.0016379794],"genre_scores_gemma":[0.82690233,0.0000050198123,0.0019326846,0.00024440774,0.00014468045,0.17059447,3.1719338e-7,0.00002949348,0.00014658022],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916255,0.000030867257,0.0002690644,0.00016998296,0.00018410347,0.00018340313],"domain_scores_gemma":[0.9992641,0.000063977255,0.00011110406,0.00036808624,0.00010763409,0.00008510641],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004898454,0.00011141205,0.00022732971,0.000084990555,0.000033568485,0.000012914143,0.00013585262,0.00008628014,0.000009169375],"category_scores_gemma":[0.000055097444,0.000083144216,0.000087321416,0.00015148797,0.000053033742,0.00006066283,0.000030895237,0.00012029515,0.000004766466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010191703,0.00027767583,0.001380426,0.0004339303,0.0000309466,0.000013890861,0.00007848136,0.0000053803606,0.98912305,0.0010528943,0.00010597285,0.006478164],"study_design_scores_gemma":[0.0017271853,0.00048558984,0.029058754,0.00020443503,0.00002243341,5.8066314e-7,0.000009559787,0.0002022197,0.9223913,0.000087365304,0.045729015,0.00008159185],"about_ca_topic_score_codex":0.0000378702,"about_ca_topic_score_gemma":0.0000029798052,"teacher_disagreement_score":0.42060405,"about_ca_system_score_codex":0.0001272136,"about_ca_system_score_gemma":0.00019238572,"threshold_uncertainty_score":0.3390523},"labels":[],"label_agreement":null},{"id":"W1873572564","doi":"10.7717/peerj.1314","title":"Autophagic flux inhibition and lysosomogenesis ensuing cellular capture and retention of the cationic drug quinacrine in murine models","year":2015,"lang":"en","type":"article","venue":"PeerJ","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"LAMP1; Bafilomycin; Vacuole; Endosome; Autophagy; Cell biology; Chloroquine; Chemistry; Lysosome; Monensin; Acridine orange; Cell culture; Biochemistry; Biology; Cytoplasm; Intracellular; Immunology","score_opus":0.023824531327133892,"score_gpt":0.2402375898454715,"score_spread":0.21641305851833761,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1873572564","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99376506,0.004443808,0.00010131194,0.0009904791,0.00005611076,0.00024146038,0.000006086387,0.000018897901,0.00037681786],"genre_scores_gemma":[0.99850583,0.00009948325,0.00008465215,0.000103717364,0.000045310368,0.000012048489,0.000030149715,0.000011201712,0.0011075804],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993399,0.000045597484,0.00017466214,0.00015515393,0.00018287305,0.000101861304],"domain_scores_gemma":[0.9995848,0.000013744808,0.00006662514,0.00018220258,0.000079055186,0.000073605646],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002044975,0.00008632591,0.00016246304,0.000066208166,0.000032269156,0.0000071328063,0.000028515913,0.00004546504,0.00001678816],"category_scores_gemma":[0.000029061308,0.0000643527,0.00003532368,0.00012377805,0.000058370875,0.000090733156,0.000035199788,0.0000788805,0.0000013563222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011577604,0.001291838,0.10456954,0.0019389483,0.0003195141,0.00027032616,0.032805435,0.0017581044,0.82671446,0.014516362,0.0024252008,0.012232513],"study_design_scores_gemma":[0.011223042,0.00024920187,0.32438332,0.00074939063,0.0004113562,0.0001967108,0.0018598167,0.049914442,0.54640037,0.06365588,0.00049867807,0.00045777584],"about_ca_topic_score_codex":0.00021968602,"about_ca_topic_score_gemma":0.000030308332,"teacher_disagreement_score":0.2803141,"about_ca_system_score_codex":0.00004202323,"about_ca_system_score_gemma":0.000051457904,"threshold_uncertainty_score":0.26242268},"labels":[],"label_agreement":null},{"id":"W1880868311","doi":"10.1080/15548627.2015.1009794","title":"USP8 and PARK2/parkin-mediated mitophagy","year":2015,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Mitophagy; Parkin; Ubiquitin; Deubiquitinating enzyme; Biology; Ubiquitin ligase; PINK1; Cell biology; Mitochondrion; Autophagy; Ubiquitin-Protein Ligases; Ubiquitin-conjugating enzyme; Biochemistry; Parkinson's disease; Gene; Apoptosis","score_opus":0.03420614248880946,"score_gpt":0.28861557421920486,"score_spread":0.25440943173039543,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1880868311","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9770139,0.00903984,0.00007067525,0.00073822396,0.00042768184,0.00032589072,0.000013657161,0.00027516132,0.012095012],"genre_scores_gemma":[0.9926186,0.00022342868,0.00047759688,0.0028556657,0.0003774406,0.000033752007,0.000058114547,0.000042765423,0.0033126173],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99859095,0.00005600957,0.00027439496,0.00036448648,0.00034040006,0.0003737691],"domain_scores_gemma":[0.99866337,0.000086383596,0.00007509418,0.00040703962,0.00011206301,0.0006560726],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019975657,0.00022708846,0.0003764574,0.000114619324,0.000063177686,0.000029258445,0.00010228664,0.00015087187,0.00033561868],"category_scores_gemma":[0.00017102614,0.00019378311,0.00008648006,0.00022058867,0.00014541886,0.00012325411,0.000058711223,0.00018208253,0.00047270558],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008369806,0.005843159,0.1789293,0.0009582745,0.004765214,0.015438261,0.012040716,0.000043830132,0.15774505,0.026192173,0.31604546,0.27362874],"study_design_scores_gemma":[0.020736225,0.001955851,0.4204239,0.0001787592,0.00051096117,0.0010318058,0.00051709835,0.00217958,0.10912277,0.0067227706,0.43549937,0.0011209345],"about_ca_topic_score_codex":0.000047556136,"about_ca_topic_score_gemma":0.0000029673956,"teacher_disagreement_score":0.27250782,"about_ca_system_score_codex":0.00005580662,"about_ca_system_score_gemma":0.00022321485,"threshold_uncertainty_score":0.7902246},"labels":[],"label_agreement":null},{"id":"W1883949615","doi":"10.1038/ncomms9045","title":"Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy","year":2015,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Research Institute for Microbial Diseases, Osaka University; Medical Research Council; Penn State College of Medicine; Université de Genève; University of Pennsylvania; Wellcome Trust; Cambridge Overseas Trust; European Commission; Institute of Genetics; Pennsylvania State University; Florida State University","keywords":"Autophagy; Annexin A2; Cell biology; PI3K/AKT/mTOR pathway; Annexin; Autophagosome; Gene knockdown; Endosome; Starvation; Biology; Signal transduction; Chemistry; Apoptosis; Biochemistry; Intracellular","score_opus":0.06573122005559297,"score_gpt":0.3485039189864079,"score_spread":0.28277269893081497,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1883949615","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.966287,0.00989461,0.00041848596,0.012116384,0.00022268297,0.0007906683,0.00006457313,0.00017854305,0.010027061],"genre_scores_gemma":[0.9913421,0.000074070194,0.007161573,0.00044890324,0.00006853974,0.000037379363,0.00050258444,0.000015689986,0.0003491507],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991114,0.00009183775,0.0002720116,0.00012544231,0.00029645985,0.00010286314],"domain_scores_gemma":[0.99805516,0.000081548584,0.00011658081,0.0010919187,0.00053761754,0.00011716219],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023222384,0.000098190314,0.0001754605,0.000120435754,0.000087333035,0.000008384356,0.00029473382,0.00022100903,0.000082620405],"category_scores_gemma":[0.00017977376,0.00009041591,0.00008486374,0.0003266991,0.00009437142,0.00014392799,0.000035039735,0.00039806063,0.00001661106],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007191684,0.0030071477,0.012582199,0.00011254104,0.0005338007,0.000004322881,0.0046638343,0.00004091188,0.52312165,0.43185806,0.0126287285,0.010727626],"study_design_scores_gemma":[0.0044078846,0.0005358319,0.8229583,0.00017419187,0.00026973715,0.00003340736,0.00045421836,0.0061785304,0.08932555,0.021660406,0.05368214,0.00031978337],"about_ca_topic_score_codex":0.000017901191,"about_ca_topic_score_gemma":0.000024413386,"teacher_disagreement_score":0.8103761,"about_ca_system_score_codex":0.0000648872,"about_ca_system_score_gemma":0.00030545727,"threshold_uncertainty_score":0.36870536},"labels":[],"label_agreement":null},{"id":"W1884950180","doi":"10.1101/gad.262758.115","title":"The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications","year":2015,"lang":"en","type":"review","venue":"Genes & Development","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":400,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Parkinson Society Canada","keywords":"Parkin; Mitophagy; PINK1; Ubiquitin ligase; Ubiquitin; Cell biology; Biology; Mitochondrion; Autophagy; Deubiquitinating enzyme; Phosphorylation; Biochemistry; Parkinson's disease; Apoptosis","score_opus":0.06805377065850439,"score_gpt":0.3437692841765888,"score_spread":0.27571551351808443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1884950180","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00020370651,0.9979719,0.0001151564,0.00019197211,0.0001680641,0.00084726134,0.00004277425,0.00002362648,0.00043556036],"genre_scores_gemma":[0.00009170682,0.9969431,0.001723021,0.00005797207,0.00012536922,0.00023114623,0.00033158046,0.000031629494,0.0004644573],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985449,0.00004500393,0.0005891715,0.00025947357,0.00037309263,0.00018837978],"domain_scores_gemma":[0.9989293,0.00010160861,0.0002201355,0.00035741067,0.00024627184,0.00014524665],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028288676,0.00025747108,0.0006993781,0.00008689616,0.00015721962,0.00001639851,0.00016786729,0.00014682229,0.00004113273],"category_scores_gemma":[0.000016707078,0.00015790074,0.00015671228,0.00014646482,0.00011040532,0.000022903392,0.00004293543,0.00012461343,0.000039486116],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017110779,0.000051579478,0.000041986437,0.0014191137,0.0005505461,0.000004165724,0.00014348219,2.2033122e-7,0.000003513455,0.00047907684,0.00042242988,0.99686676],"study_design_scores_gemma":[0.0002713824,0.00002504485,0.0030840242,0.0011112806,0.00046195148,0.000035561825,0.000015736223,0.000002436266,0.000025537289,0.00033988853,0.99446815,0.00015899623],"about_ca_topic_score_codex":0.0000043357927,"about_ca_topic_score_gemma":0.000011052326,"teacher_disagreement_score":0.9967078,"about_ca_system_score_codex":0.000054583943,"about_ca_system_score_gemma":0.0021224443,"threshold_uncertainty_score":0.6439005},"labels":[],"label_agreement":null},{"id":"W1888981292","doi":"10.1152/ajpregu.00413.2014","title":"Modulation of autophagy signaling with resistance exercise and protein ingestion following short-term energy deficit","year":2015,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Sport Centre Pacific; University of Toronto; McMaster University","funders":"","keywords":"ATG5; Autophagy; Internal medicine; Endocrinology; Ingestion; Skeletal muscle; Medicine; Chemistry; Biochemistry; Apoptosis","score_opus":0.024683269470007693,"score_gpt":0.28623717958475164,"score_spread":0.26155391011474394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1888981292","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963804,0.0022579771,0.0009492787,0.00005001272,0.000052262458,0.00021733656,0.0000052313935,0.000013738805,0.00007377006],"genre_scores_gemma":[0.99782175,0.00007082148,0.0018273315,0.00007226004,0.00010304553,0.000024947673,0.00001637962,0.000016728707,0.000046730802],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983636,0.00032768314,0.0005289697,0.0003311968,0.00022370224,0.00022485762],"domain_scores_gemma":[0.9982536,0.00011651215,0.0007039545,0.00019613896,0.0005233241,0.00020650789],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018587722,0.000309777,0.0012766685,0.00018841327,0.000082789,0.000008341482,0.00010344902,0.000074904536,0.000007806335],"category_scores_gemma":[0.000023320114,0.00020678769,0.0001417368,0.00024070866,0.0010623328,0.0001991306,0.00003149416,0.00025341363,4.344157e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00740861,0.00022405594,0.0017333152,0.00003669079,0.0005721117,0.000011721346,0.0022348324,0.0003260371,0.98241705,0.0027921873,0.000036884547,0.0022064776],"study_design_scores_gemma":[0.0037760667,0.01000991,0.5758963,0.0017495636,0.0004776943,0.00006586877,0.008582876,0.0011968438,0.38863942,0.009025188,0.000082777864,0.00049746456],"about_ca_topic_score_codex":0.00002974084,"about_ca_topic_score_gemma":0.000010794942,"teacher_disagreement_score":0.59377766,"about_ca_system_score_codex":0.000060831087,"about_ca_system_score_gemma":0.00020788504,"threshold_uncertainty_score":0.8432557},"labels":[],"label_agreement":null},{"id":"W1893400247","doi":"10.1089/ars.2013.5410","title":"Reactive Oxygen Species Regulation of Autophagy in Skeletal Muscles","year":2013,"lang":"en","type":"article","venue":"Antioxidants and Redox Signaling","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Skeletal muscle; mTORC1; Cell biology; Reactive oxygen species; Protein kinase B; Biology; AMPK; Lysosome; AMP-activated protein kinase; Protein kinase A; Mitochondrion; Autophagosome; Phosphorylation; Chemistry; Biochemistry; Apoptosis; Endocrinology","score_opus":0.01130463003375285,"score_gpt":0.2444783332753109,"score_spread":0.23317370324155806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1893400247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968442,0.0010447635,0.00007515363,0.00013805281,0.000045931163,0.00025507782,0.0000032490602,0.000021674605,0.0015719307],"genre_scores_gemma":[0.9987029,0.00018512257,0.00036938084,0.000076644064,0.00009028803,0.0000075797025,0.000011407948,0.0000124337075,0.00054428016],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992468,0.000027919497,0.00025665073,0.00017111754,0.00014745988,0.00015010095],"domain_scores_gemma":[0.9996138,0.0000422497,0.000097668155,0.00011900901,0.00006679185,0.00006043434],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010674048,0.000101900165,0.0002410999,0.00012645774,0.00004487358,0.000012921285,0.000034964563,0.00007117203,0.00033571298],"category_scores_gemma":[0.000021819766,0.00008054646,0.000060111917,0.00013153016,0.00009301742,0.00015643783,0.000016933374,0.00008155607,0.0000076662955],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003676533,0.000109281835,0.007405233,0.000060104303,0.00005575097,0.000015632831,0.00048710508,0.000008953833,0.9828971,0.0008296992,0.000045961773,0.008048438],"study_design_scores_gemma":[0.0007980265,0.0000886394,0.7653576,0.00021565499,0.000025709624,0.000012230144,0.0004198061,0.00042659068,0.23059553,0.0018124771,0.00016339643,0.00008430274],"about_ca_topic_score_codex":0.00012910945,"about_ca_topic_score_gemma":0.0000022600116,"teacher_disagreement_score":0.7579524,"about_ca_system_score_codex":0.000014166448,"about_ca_system_score_gemma":0.00003022053,"threshold_uncertainty_score":0.36758217},"labels":[],"label_agreement":null},{"id":"W1894136033","doi":"10.1111/all.12761","title":"Autophagy in airway diseases: a new frontier in human asthma?","year":2015,"lang":"en","type":"review","venue":"Allergy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":97,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; SickKids Foundation; University of Toronto","funders":"National Heart, Lung, and Blood Institute; Manitoba Medical Service Foundation","keywords":"Autophagy; Asthma; ATG5; Biology; Fibrosis; Cell biology; Immunology; Medicine; Pathology; Genetics","score_opus":0.04262299843713349,"score_gpt":0.3662190483362287,"score_spread":0.3235960498990952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1894136033","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011377044,0.9936406,0.000008691051,0.000053656553,0.00030582582,0.00090507517,0.00003253586,0.00008073368,0.004859113],"genre_scores_gemma":[0.00006759461,0.9857915,0.0000676998,0.0003077347,0.00067040924,0.00017805726,0.000658535,0.00012278755,0.012135662],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974369,0.00018238644,0.0008342959,0.0006355212,0.00039588913,0.0005150142],"domain_scores_gemma":[0.998366,0.000040958214,0.00021595298,0.0007795417,0.000037019923,0.0005605288],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001699795,0.000556296,0.002435358,0.00055693294,0.000026112992,0.000022105523,0.00033665675,0.00045169643,0.001397604],"category_scores_gemma":[0.00004363952,0.00046062455,0.0005372016,0.0005016779,0.000056374283,0.000089425455,0.000098562865,0.00053473865,0.00024600708],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005871272,0.0005624355,0.000025703246,0.0024895566,0.00039545092,0.0014209676,0.0001594865,0.0000019147185,2.6616615e-7,0.000548974,0.03650008,0.95783645],"study_design_scores_gemma":[0.0023956615,0.0001644243,0.0004069787,0.007579995,0.00018927481,0.000025466474,0.000014274802,0.000006999824,5.2704894e-7,0.0006710148,0.9881534,0.0003919861],"about_ca_topic_score_codex":0.00046081524,"about_ca_topic_score_gemma":0.0002098845,"teacher_disagreement_score":0.9574445,"about_ca_system_score_codex":0.00042907006,"about_ca_system_score_gemma":0.0017520746,"threshold_uncertainty_score":0.9997845},"labels":[],"label_agreement":null},{"id":"W1898472738","doi":"10.1161/circresaha.117.306859","title":"Interdependence of Parkin-Mediated Mitophagy and Mitochondrial Fission in Adult Mouse Hearts","year":2015,"lang":"en","type":"article","venue":"Circulation Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":211,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Heart, Lung, and Blood Institute","keywords":"Mitophagy; Parkin; Mitochondrial fission; Mitochondrion; Cell biology; Biology; PINK1; Genetics; Medicine; Autophagy; Internal medicine; Apoptosis","score_opus":0.09883074167636792,"score_gpt":0.40333350957305114,"score_spread":0.30450276789668324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1898472738","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99783,0.00043602684,0.000058387748,0.00048776346,0.00008351651,0.00041829175,0.000004507611,0.000017846849,0.0006636846],"genre_scores_gemma":[0.99938625,0.000068029665,0.00009003904,0.000054878725,0.000104023005,0.000022251339,0.00003148773,0.000011339252,0.00023167105],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99854934,0.00018351265,0.00023605462,0.00021244655,0.0006174978,0.00020112716],"domain_scores_gemma":[0.998923,0.00014978736,0.000037553124,0.00022150417,0.00043685437,0.00023129155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004232953,0.000069557726,0.00017009731,0.0002914578,0.000030375017,0.0000138108835,0.00006062609,0.00010161002,0.00008687137],"category_scores_gemma":[0.0008575718,0.00006174837,0.000028596764,0.00033347038,0.00012334099,0.00009850232,0.000044227283,0.00022946906,0.000028647924],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036945178,0.0009586231,0.5044712,0.00032708974,0.00010683681,0.00027638895,0.00442224,0.00023156713,0.46913135,0.00075772416,0.004974456,0.010648022],"study_design_scores_gemma":[0.012489779,0.0007447474,0.8852266,0.0005262969,0.00002231973,0.000046019908,0.0013791295,0.022300549,0.07353774,0.0026128332,0.0008681304,0.0002458337],"about_ca_topic_score_codex":0.00020988403,"about_ca_topic_score_gemma":0.000029897927,"teacher_disagreement_score":0.3955936,"about_ca_system_score_codex":0.00006650215,"about_ca_system_score_gemma":0.00019777892,"threshold_uncertainty_score":0.25180253},"labels":[],"label_agreement":null},{"id":"W1908202618","doi":"10.1002/jcp.24781","title":"Palmitate Induces ER Stress and Autophagy in H9c2 Cells: Implications for Apoptosis and Adiponectin Resistance","year":2014,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Diabetes Association","keywords":"Autophagy; Unfolded protein response; Lipotoxicity; Programmed cell death; Cell biology; Endoplasmic reticulum; Apoptosis; Viability assay; Intracellular; Chemistry; Biology; Internal medicine; Endocrinology; Biochemistry; Medicine; Insulin resistance","score_opus":0.013946938372723386,"score_gpt":0.27122538138878066,"score_spread":0.2572784430160573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1908202618","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99536616,0.0029054885,0.0004985129,0.0008637502,0.0000972608,0.00015409691,0.000008779072,0.0000056849312,0.00010026867],"genre_scores_gemma":[0.99807763,0.0005487227,0.0007215316,0.0003112207,0.00020117582,0.000011932804,0.0000053161957,0.000013805258,0.000108686945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992397,0.00008302739,0.0003094696,0.0001494532,0.000056514946,0.00016187971],"domain_scores_gemma":[0.9992053,0.0002207921,0.0002312158,0.0001360531,0.00009791693,0.000108747176],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020962553,0.00010329997,0.00035275504,0.00011533897,0.000050110386,0.0000083105215,0.00006578374,0.000084041436,0.000010742275],"category_scores_gemma":[0.000062782194,0.00008253548,0.00006708162,0.00007204533,0.00008900974,0.000062102634,0.000016414826,0.00015089918,7.652356e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039156646,0.00012809719,0.00058803696,0.0001229288,0.00008007253,0.0000026990076,0.00019474437,0.0000070799533,0.9954801,0.00095138117,0.00016721753,0.0018860477],"study_design_scores_gemma":[0.0036852728,0.00072742195,0.25744867,0.00018568787,0.00016130618,0.000021490749,0.00012634492,0.00010562129,0.71480584,0.019617826,0.0029557243,0.0001588083],"about_ca_topic_score_codex":0.0000036115584,"about_ca_topic_score_gemma":0.0000031424108,"teacher_disagreement_score":0.2806743,"about_ca_system_score_codex":0.000016186112,"about_ca_system_score_gemma":0.00004275624,"threshold_uncertainty_score":0.33656994},"labels":[],"label_agreement":null},{"id":"W1909231446","doi":"10.1016/j.cub.2015.08.031","title":"The Pro-apoptotic STK38 Kinase Is a New Beclin1 Partner Positively Regulating Autophagy","year":2015,"lang":"en","type":"article","venue":"Current Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; Centre National de la Recherche Scientifique; National Centre for the Replacement, Refinement and Reduction of Animals in Research; Institut National de la Santé et de la Recherche Médicale; Institut National Du Cancer; Institut national de la recherche scientifique; Wellcome Trust; National Centre for the Replacement Refinement and Reduction of Animals in Research; Association pour la Recherche sur le Cancer","keywords":"Autophagy; Cell biology; BAG3; Regulator; ULK1; Biology; Exocyst; Autophagosome; Programmed cell death; ATG8; Kinase; Protein kinase A; Apoptosis; Genetics; Gene","score_opus":0.10497042744549316,"score_gpt":0.395921834581354,"score_spread":0.2909514071358608,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1909231446","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9661837,0.025446448,0.00044397733,0.004271892,0.0014187763,0.0006752584,0.000019374334,0.00014810437,0.0013924276],"genre_scores_gemma":[0.9950061,0.0002912481,0.00018437122,0.0010307073,0.0010015799,0.000040315306,0.00007676216,0.000024847188,0.0023441056],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99867404,0.00012887914,0.00030696476,0.0003318652,0.0001451216,0.0004131622],"domain_scores_gemma":[0.9988662,0.00011525702,0.00013183765,0.00038293935,0.0001331881,0.00037058993],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026273407,0.0001946172,0.00028286382,0.000049040722,0.00014350857,0.000021401234,0.00015879313,0.00011381113,0.00011215779],"category_scores_gemma":[0.0001936996,0.00011937242,0.00012762888,0.00014845042,0.00019437565,0.000044366017,0.000072886,0.00023382161,0.00019976779],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013019948,0.00062587165,0.017511023,0.000075576645,0.0004300165,0.000049782764,0.0026390313,0.0000038127293,0.0072658896,0.019430453,0.05308348,0.89758307],"study_design_scores_gemma":[0.01102257,0.0024688954,0.07736717,0.00036740126,0.00049790856,0.00014184469,0.00045101735,0.0019492686,0.052684203,0.033362266,0.8189,0.0007874375],"about_ca_topic_score_codex":0.000027322281,"about_ca_topic_score_gemma":0.0000029156988,"teacher_disagreement_score":0.89679563,"about_ca_system_score_codex":0.00006847433,"about_ca_system_score_gemma":0.0004268724,"threshold_uncertainty_score":0.4867866},"labels":[],"label_agreement":null},{"id":"W1915075397","doi":"10.1139/cjpp-2014-0017","title":"Impairment of autophagy in endothelial cells prevents shear-stress-induced increases in nitric oxide bioavailability","year":2014,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; U.S. Department of Veterans Affairs","keywords":"Autophagy; Enos; Nitric oxide; Cell biology; Reactive oxygen species; Nitric oxide synthase; Nitric Oxide Synthase Type III; Endothelial dysfunction; Chemistry; Endothelial stem cell; Oxidative stress; Biology; Biochemistry; Endocrinology; Apoptosis; In vitro","score_opus":0.011012576588472054,"score_gpt":0.27607727529897,"score_spread":0.265064698710498,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1915075397","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99865544,0.0006857211,0.0000019150914,0.00011502965,0.00020015571,0.00021158026,0.00003989098,0.0000021258288,0.00008815194],"genre_scores_gemma":[0.99887496,0.00014905931,0.000039449005,0.00077418616,0.000114576986,0.000006481094,0.0000040329373,0.0000061454202,0.000031094984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986457,0.00040266666,0.0004625826,0.0001516014,0.000053766737,0.0002836759],"domain_scores_gemma":[0.9991113,0.00020961983,0.00018585807,0.00009714538,0.00006398492,0.000332076],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037311172,0.00012399236,0.00050118234,0.00045516976,0.000028587485,0.0000016836685,0.000112990674,0.00013794024,0.00070048857],"category_scores_gemma":[0.00005160922,0.000108872766,0.00008059851,0.00018888367,0.0001860837,0.000046343786,0.000013214005,0.0002990808,0.000002050163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007519979,0.0003968424,0.06777687,0.00017934706,0.00009849869,0.00016168892,0.000104777064,0.00003784316,0.9293758,0.00003867973,0.00021642022,0.00086117553],"study_design_scores_gemma":[0.0036167111,0.0004896143,0.497096,0.00006649075,0.00006322885,0.000034745208,0.000025466927,0.0000717908,0.4975147,0.0007876704,0.00017057736,0.000063009924],"about_ca_topic_score_codex":0.0036504373,"about_ca_topic_score_gemma":0.00057722995,"teacher_disagreement_score":0.43186116,"about_ca_system_score_codex":0.000097836295,"about_ca_system_score_gemma":0.0009341676,"threshold_uncertainty_score":0.7669859},"labels":[],"label_agreement":null},{"id":"W1919353","doi":"10.1093/jnen/64.2.113","title":"Extensive Involvement of Autophagy in Alzheimer Disease: An Immuno-Electron Microscopy Study","year":2005,"lang":"en","type":"article","venue":"Journal of Neuropathology & Experimental Neurology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1580,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health","keywords":"Autophagy; Vacuole; Organelle; Cell biology; Neurite; Biology; Cathepsin D; Pathology; Lysosome; Axoplasmic transport; Alzheimer's disease; Neurodegeneration; Cytoplasm; Biochemistry; Medicine; Apoptosis; Disease","score_opus":0.020938871022128252,"score_gpt":0.3522021693228293,"score_spread":0.331263298300701,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1919353","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98680615,0.0115517955,0.0000074568943,0.00056211074,0.00048394944,0.00053676515,0.0000037540487,0.000017806924,0.000030204814],"genre_scores_gemma":[0.99494535,0.00017533588,0.00013590329,0.004397405,0.000267,0.000013906066,0.0000046215223,0.000049393428,0.000011113904],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9971907,0.0006072272,0.0010769685,0.0003866683,0.00029863685,0.00043979927],"domain_scores_gemma":[0.99846536,0.00007716936,0.00058560295,0.00044216734,0.00014955024,0.0002801494],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040301206,0.0002862055,0.0007792416,0.00042034723,0.000049595594,0.0000067512,0.00028006214,0.000105363564,0.00010381341],"category_scores_gemma":[0.000038950697,0.0002539448,0.0002057571,0.00017324871,0.0002615384,0.0001948222,0.000091044516,0.0005837555,0.0000087953],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0109218415,0.008927781,0.03929506,0.0000055483915,0.00012104272,0.011004396,0.001616095,0.00006449474,0.9271899,0.000029889594,0.000050419276,0.0007735708],"study_design_scores_gemma":[0.0061405255,0.021699496,0.53367984,0.000013767841,0.00020227981,0.0020077098,0.0003855091,0.000035341804,0.43528488,0.000031337488,0.0003785386,0.00014073796],"about_ca_topic_score_codex":0.000007686597,"about_ca_topic_score_gemma":0.000003917618,"teacher_disagreement_score":0.49438483,"about_ca_system_score_codex":0.000047588994,"about_ca_system_score_gemma":0.00016279114,"threshold_uncertainty_score":0.9999913},"labels":[],"label_agreement":null},{"id":"W1921764183","doi":"10.1002/mc.22264","title":"Evidence of MTCBP‐1 interaction with the cytoplasmic domain of MT1‐MMP: Implications in the autophagy cell index of high‐grade glioblastoma","year":2015,"lang":"en","type":"article","venue":"Molecular Carcinogenesis","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal; Quebec - Clinical Research Organization in Cancer","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Autophagy; Cytoplasm; Cell biology; Intracellular; Matrix metalloproteinase; Signal transduction; Biochemistry; Apoptosis","score_opus":0.026899446068789894,"score_gpt":0.28074855324388226,"score_spread":0.25384910717509235,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1921764183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99346733,0.0023023398,0.0022049746,0.0013097925,0.000030305957,0.000508689,0.000012088451,0.000010761064,0.00015370942],"genre_scores_gemma":[0.9993051,0.000051848874,0.0002224586,0.0002815489,0.00002009856,0.000072577684,0.0000054847624,0.000021434023,0.000019433826],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99862367,0.00022695617,0.00034844058,0.00020481988,0.00043337734,0.00016273952],"domain_scores_gemma":[0.9985557,0.00015406423,0.00027819417,0.0007363665,0.00020869047,0.00006697466],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033861684,0.00015041973,0.0003173382,0.00016150558,0.000028211705,0.00000531929,0.00029541785,0.00006981966,0.000013069779],"category_scores_gemma":[0.000038824473,0.00008895093,0.000132535,0.0006120271,0.00018189862,0.000060724557,0.00003925905,0.000118336575,0.000002121228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015670483,0.0005856132,0.0359087,0.00022216322,0.00016571984,0.00007076148,0.0032784378,0.0010390307,0.95483994,0.0013318564,0.00013186313,0.0008588384],"study_design_scores_gemma":[0.0013078668,0.0007132649,0.18600549,0.00015754471,0.00019673812,0.000055610555,0.0012802721,0.00010211577,0.80951005,0.0005452083,0.00004227782,0.00008357607],"about_ca_topic_score_codex":0.00035398165,"about_ca_topic_score_gemma":0.000057876146,"teacher_disagreement_score":0.15009679,"about_ca_system_score_codex":0.000055294662,"about_ca_system_score_gemma":0.00023411824,"threshold_uncertainty_score":0.36273137},"labels":[],"label_agreement":null},{"id":"W1933880153","doi":"10.1016/j.freeradbiomed.2015.10.404","title":"ROS-dependent activation of autophagy is a critical mechanism for the induction of anti-glioma effect of sanguinarine","year":2015,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Terry Fox Foundation; National Research Foundation; Al Jalila Foundation; Sheikh Hamdan Bin Rashid Al Maktoum Award for Medical Sciences; Utah Agricultural Experiment Station","keywords":"Autophagy; Programmed cell death; ATG5; Cell biology; Apoptosis; Chemistry; Cancer research; Biology; Biochemistry","score_opus":0.028399038233073378,"score_gpt":0.35447853566941556,"score_spread":0.3260794974363422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1933880153","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9861289,0.0022033188,0.0050765285,0.005692594,0.00027304038,0.00047574885,0.000028859065,0.000013735474,0.00010725999],"genre_scores_gemma":[0.99898094,0.00012518682,0.00016685198,0.00035099644,0.00028993434,0.000025659701,0.0000252294,0.00000793525,0.000027293188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991118,0.000091376845,0.00033374297,0.00016188173,0.00016819335,0.00013301487],"domain_scores_gemma":[0.99861044,0.00070627325,0.00012820304,0.00025205032,0.00017925314,0.00012379733],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006063235,0.000111773625,0.00052099256,0.00009927283,0.000032571013,5.266443e-7,0.000092145994,0.00019538119,0.000082652106],"category_scores_gemma":[0.0022255594,0.000059489226,0.00006650418,0.00011771614,0.00086034206,0.000024611385,0.00003181438,0.00012217063,3.4919654e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033546288,0.00029192652,0.0025251657,0.0005012402,0.00038868928,0.000009239777,0.00052165746,3.3252147e-7,0.9051897,0.07363409,0.0019532272,0.011630099],"study_design_scores_gemma":[0.008617844,0.008752604,0.007951908,0.00019307222,0.00046659063,0.00007315731,0.00015614346,0.0002496734,0.95360523,0.019539604,0.00033423258,0.000059915958],"about_ca_topic_score_codex":0.00009120205,"about_ca_topic_score_gemma":7.213253e-7,"teacher_disagreement_score":0.054094486,"about_ca_system_score_codex":0.000013104821,"about_ca_system_score_gemma":0.00006146841,"threshold_uncertainty_score":0.31699663},"labels":[],"label_agreement":null},{"id":"W1935072652","doi":"10.1016/j.cmet.2015.05.016","title":"AMPK Activation of Muscle Autophagy Prevents Fasting-Induced Hypoglycemia and Myopathy during Aging","year":2015,"lang":"en","type":"article","venue":"Cell Metabolism","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":243,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; AMPK; AMP-activated protein kinase; Endocrinology; Mitophagy; Internal medicine; Skeletal muscle; ULK1; Protein kinase A; Myopathy; Mechanistic target of rapamycin; Beta oxidation; Chemistry; Biology; Cell biology; Phosphorylation; Medicine; Biochemistry; Metabolism","score_opus":0.023987967176123674,"score_gpt":0.26526255980428337,"score_spread":0.2412745926281597,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1935072652","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961261,0.0015852991,0.00008279599,0.000050794722,0.00024223738,0.00025927162,0.000002933832,0.000065050925,0.0015855104],"genre_scores_gemma":[0.9984985,0.00006733683,0.00041635137,0.000109920205,0.00027465617,0.000013938415,0.0000087520975,0.00002995422,0.0005805629],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898076,0.000051321003,0.00025594461,0.0002410517,0.00025836137,0.00021258609],"domain_scores_gemma":[0.9992427,0.000028353488,0.00016172667,0.0002634902,0.00007803918,0.00022568941],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016149793,0.0001536187,0.00032208892,0.00011831139,0.00005297104,0.000011786665,0.000071883165,0.00008160039,0.000031909338],"category_scores_gemma":[0.00008091738,0.00014120656,0.00006650345,0.00016051916,0.000034593453,0.00015421165,0.000052617892,0.00014049531,0.000009596275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014862673,0.0001700218,0.0015889708,0.00014884789,0.000043972574,0.000017094902,0.0015506223,0.000009862109,0.98542655,0.000064833446,0.000032095635,0.0107985325],"study_design_scores_gemma":[0.0033972492,0.000054270342,0.21971571,0.0000794443,0.00010776931,0.0000064093633,0.00020005598,0.0001641422,0.77531964,0.00029097666,0.00054874003,0.00011562449],"about_ca_topic_score_codex":0.00003404226,"about_ca_topic_score_gemma":2.0206093e-7,"teacher_disagreement_score":0.21812674,"about_ca_system_score_codex":0.000027660197,"about_ca_system_score_gemma":0.00008051001,"threshold_uncertainty_score":0.57582366},"labels":[],"label_agreement":null},{"id":"W1938770868","doi":"10.1080/15548627.2015.1078962","title":"Precision autophagy: Will the next wave of selective autophagy markers and specific autophagy inhibitors feed clinical pipelines?","year":2015,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Centre for Drug Research and Development; University of British Columbia; BC Cancer Agency; Simon Fraser University; Terry Fox Research Institute; Burnaby Hospital","funders":"Canadian Institutes of Health Research; University of South Dakota","keywords":"Autophagy; Biology; Computational biology; Biomarker; Autophagosome; Biomarker discovery; Context (archaeology); Bioinformatics; Cell biology; Proteomics; Biochemistry; Gene","score_opus":0.06005000145771153,"score_gpt":0.3277088708769142,"score_spread":0.2676588694192027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1938770868","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97329956,0.015324454,0.00047887472,0.0011262083,0.0025884584,0.0020902455,0.000055609864,0.0004633251,0.0045732744],"genre_scores_gemma":[0.98932886,0.0016374688,0.0017131128,0.0015667551,0.001680845,0.00010410338,0.00007702478,0.00018148364,0.0037103198],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9929393,0.00082770525,0.002218174,0.0014603197,0.0014574094,0.0010970887],"domain_scores_gemma":[0.9942491,0.0011794897,0.0009018233,0.001669255,0.00086386426,0.0011364367],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0025983294,0.00092522916,0.0017721131,0.00043808433,0.0003257463,0.00013690439,0.0005804393,0.0007466819,0.00055530254],"category_scores_gemma":[0.0010656919,0.0006732421,0.0007427258,0.0011803485,0.0012180653,0.00071972015,0.0004050447,0.00117998,0.00015027747],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.024405321,0.00851074,0.013373386,0.00087257964,0.0052305306,0.0036628337,0.012366054,0.00022956371,0.07632183,0.014830404,0.2003352,0.6398615],"study_design_scores_gemma":[0.03181925,0.0074959714,0.61722696,0.00091223035,0.0015793735,0.0015102281,0.0024977915,0.015258974,0.18686989,0.015394538,0.11704425,0.002390538],"about_ca_topic_score_codex":0.00012450582,"about_ca_topic_score_gemma":0.000008863069,"teacher_disagreement_score":0.637471,"about_ca_system_score_codex":0.00030294474,"about_ca_system_score_gemma":0.0010749592,"threshold_uncertainty_score":0.99957186},"labels":[],"label_agreement":null},{"id":"W1939952622","doi":"10.1186/s12964-015-0115-9","title":"Autophagy capacity and sub-mitochondrial heterogeneity shape Bnip3-induced mitophagy regulation of apoptosis","year":2015,"lang":"en","type":"article","venue":"Cell Communication and Signaling","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Toronto; Bundesministerium für Bildung und Forschung; Deutsches Krebsforschungszentrum","keywords":"Mitophagy; Cell biology; Autophagy; Crosstalk; Mitochondrion; Biology; Apoptosis; Programmed cell death; Biochemistry","score_opus":0.05985397331381534,"score_gpt":0.28354540032593006,"score_spread":0.22369142701211472,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1939952622","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957924,0.0028811381,0.00021114123,0.000111654495,0.000070251765,0.00026193552,0.000003873092,0.00004362349,0.0006239823],"genre_scores_gemma":[0.9975056,0.00028516783,0.0018863754,0.0001521297,0.00006567574,0.000012670151,0.000041343857,0.00001568844,0.00003534118],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902034,0.00017200239,0.00030839222,0.0001867807,0.00018783502,0.00012467266],"domain_scores_gemma":[0.9988848,0.00009632381,0.0001682492,0.0004807716,0.00017189494,0.00019797399],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002672152,0.00013015894,0.0002684282,0.000079838,0.00011828738,0.00002356147,0.00010372394,0.000120323995,0.0000339664],"category_scores_gemma":[0.000052508556,0.00012499599,0.000058838006,0.00011152004,0.000113361915,0.000113768176,0.00006876202,0.00014565302,0.0000032216562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025705292,0.00014449049,0.0014767611,0.00007374094,0.000043988905,4.9048276e-7,0.0010653996,0.000013193048,0.99344164,0.00031065012,0.00005804042,0.0031145748],"study_design_scores_gemma":[0.0021688545,0.00015558356,0.0097249495,0.00006703654,0.00007672821,0.0000071502095,0.00019853137,0.0036619152,0.9827587,0.00089241675,0.00016858328,0.0001195387],"about_ca_topic_score_codex":0.000052054038,"about_ca_topic_score_gemma":0.000003677697,"teacher_disagreement_score":0.010682905,"about_ca_system_score_codex":0.000031011285,"about_ca_system_score_gemma":0.000059690614,"threshold_uncertainty_score":0.50971884},"labels":[],"label_agreement":null},{"id":"W1940156094","doi":"10.1002/oby.20646","title":"Hyperphagia: Current concepts and future directions proceedings of the 2nd international conference on hyperphagia","year":2014,"lang":"en","type":"article","venue":"Obesity","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Center for Research Resources; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Eye Institute; National Institutes of Health","keywords":"Scope (computer science); Population; Medicine; Political science; Computer science; Environmental health","score_opus":0.013867244002102128,"score_gpt":0.291146550741264,"score_spread":0.27727930673916185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1940156094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9791323,0.00045776248,0.000004750364,0.0014029559,0.00058500806,0.0001539391,0.0000113689985,0.0000257549,0.018226193],"genre_scores_gemma":[0.99830866,0.0005835634,0.00003675927,0.0002552377,0.00044574338,0.000007577557,0.0000034605632,0.0000061035603,0.0003529003],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99947155,0.000010850747,0.00009966612,0.00015000008,0.00018493539,0.00008298454],"domain_scores_gemma":[0.99961925,0.000016753598,0.000063267114,0.0000990531,0.00013580253,0.00006585464],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007318304,0.000085337975,0.00013460674,0.000026960835,0.00008024191,0.000011606303,0.00009007211,0.00004540473,0.00024551383],"category_scores_gemma":[0.000029199346,0.000055718116,0.00005386908,0.00006735244,0.00011207935,0.000047575115,0.000033655404,0.00015185228,0.000008629704],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041170858,0.0016432529,0.6110877,0.0002269857,0.00029217562,0.0000029046982,0.0021844504,4.0517554e-7,0.023712283,0.1863461,0.007103505,0.16698857],"study_design_scores_gemma":[0.0010482179,0.000119538454,0.88205487,0.00011988299,0.00007534021,0.000017814567,0.00015397002,0.00021285652,0.010910234,0.0012673426,0.10393073,0.0000892362],"about_ca_topic_score_codex":0.0000055601786,"about_ca_topic_score_gemma":0.0000012246635,"teacher_disagreement_score":0.27096716,"about_ca_system_score_codex":0.00002087955,"about_ca_system_score_gemma":0.000029567023,"threshold_uncertainty_score":0.26882043},"labels":[],"label_agreement":null},{"id":"W1940659856","doi":"10.1111/j.1600-065x.2012.01141.x","title":"Autophagy inhibition in cancer therapy: metabolic considerations for antitumor immunity","year":2012,"lang":"en","type":"review","venue":"Immunological Reviews","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":103,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Autophagy; Biology; Immunity; Cancer; Cancer cell; Cancer research; Immunology; Immunogenic cell death; Tumor microenvironment; Immune tolerance; Immunotherapy","score_opus":0.319704218672984,"score_gpt":0.4570175041346782,"score_spread":0.1373132854616942,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1940659856","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001529765,0.99244195,0.000024926898,0.00010473178,0.0003756438,0.0064145457,0.00011477221,0.00008759264,0.00028288175],"genre_scores_gemma":[0.00011081443,0.9913942,0.00045386335,0.0007764388,0.0003414975,0.0062263682,0.0003209069,0.000060123915,0.0003157494],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99662066,0.00076249696,0.0014533012,0.00046044833,0.00015594666,0.00054717006],"domain_scores_gemma":[0.9979169,0.00050504337,0.00061655475,0.0007333545,0.00009578517,0.00013237035],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00094295706,0.00062060583,0.0040544723,0.00023730643,0.0001545187,0.00003591915,0.00012882017,0.00053927314,0.002203094],"category_scores_gemma":[0.0005881134,0.00037859377,0.0013690148,0.0004313856,0.00016791203,0.00013370195,0.00006319339,0.00080828776,0.00025927447],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035223253,0.00057117984,0.0000020757977,0.003600144,0.00023569555,0.000022880518,0.000031693107,3.2865273e-8,0.0000589441,0.0019570712,0.000139649,0.99334544],"study_design_scores_gemma":[0.0010332306,0.00016186692,0.00020548493,0.008316734,0.0011137903,0.00010008485,0.0000033903063,6.15582e-7,0.0000901587,0.00068497873,0.9879322,0.0003574386],"about_ca_topic_score_codex":0.000042626463,"about_ca_topic_score_gemma":0.00000632823,"teacher_disagreement_score":0.992988,"about_ca_system_score_codex":0.00016616094,"about_ca_system_score_gemma":0.000445599,"threshold_uncertainty_score":0.9998666},"labels":[],"label_agreement":null},{"id":"W1946065463","doi":"10.1210/en.2015-1162","title":"Pressure Overload-Induced Cardiac Dysfunction in Aged Male Adiponectin Knockout Mice Is Associated With Autophagy Deficiency","year":2015,"lang":"en","type":"article","venue":"Endocrinology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; York University","funders":"","keywords":"Autophagy; Adiponectin; Internal medicine; Endocrinology; Pressure overload; Heart failure; Cardiac function curve; Biology; Cardiac fibrosis; Medicine; Insulin resistance; Diabetes mellitus; Apoptosis; Biochemistry","score_opus":0.025255462675271446,"score_gpt":0.2720649219913974,"score_spread":0.24680945931612597,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1946065463","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98763657,0.0033493657,0.000018216306,0.00038382303,0.00054115086,0.00048532741,0.000020691916,0.00017757156,0.007387274],"genre_scores_gemma":[0.9930552,0.000050127943,0.000046053665,0.0007645671,0.00012444283,0.00007627507,0.000045732177,0.000035895842,0.005801672],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981596,0.00021667659,0.0002733621,0.00045416784,0.00029254745,0.000603657],"domain_scores_gemma":[0.9990858,0.00009562824,0.00012611008,0.00037730084,0.00012448312,0.00019070275],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015511597,0.00023781232,0.00051206537,0.00020644836,0.0000664264,0.000010010256,0.00011835898,0.00018346158,0.0003552757],"category_scores_gemma":[0.00022223336,0.0002056617,0.00009533091,0.0003657375,0.00008824332,0.000104820625,0.000042790045,0.00042892495,0.00013538329],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009902257,0.0052860007,0.62216455,0.00027138193,0.004078582,0.008648307,0.01692458,0.00029449907,0.2732597,0.002867801,0.035811376,0.02049096],"study_design_scores_gemma":[0.016313432,0.0028462806,0.8767068,0.00013725979,0.0007496907,0.0005979705,0.0011930058,0.00028279074,0.085276075,0.00032048736,0.014963149,0.00061307783],"about_ca_topic_score_codex":0.00038940384,"about_ca_topic_score_gemma":0.000058176487,"teacher_disagreement_score":0.25454223,"about_ca_system_score_codex":0.0001669317,"about_ca_system_score_gemma":0.0002913342,"threshold_uncertainty_score":0.83866405},"labels":[],"label_agreement":null},{"id":"W1949799299","doi":"10.1101/pdb.prot086280","title":"Detection of p62 on Paraffin Sections by Immunohistochemistry","year":2015,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Tata Trusts; Lady Tata Memorial Trust","keywords":"Sequestosome 1; Autophagy; Autophagosome; Western blot; Immunohistochemistry; Signal transducing adaptor protein; Cell biology; Protein aggregation; Blot; Chemistry; Biology; Biochemistry; Gene; Phosphorylation; Apoptosis; Immunology","score_opus":0.026139341616082397,"score_gpt":0.3184564122886926,"score_spread":0.2923170706726102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1949799299","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95966285,0.00024569247,0.00070411625,0.000075346645,0.00009380661,0.037014466,0.000011273395,0.00019644447,0.0019959807],"genre_scores_gemma":[0.9513406,0.000002133055,0.00010337911,0.00009484238,0.000104046405,0.047868185,0.0000010052371,0.00002427355,0.0004615057],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991912,0.000021950142,0.0002165242,0.0001889453,0.00022757976,0.00015375405],"domain_scores_gemma":[0.99921185,0.000019653753,0.000108867105,0.00039857393,0.00010621213,0.0001548556],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014334057,0.000119986384,0.00019772309,0.0000488237,0.00005082129,0.000010895241,0.00008438473,0.0000949814,0.000032950316],"category_scores_gemma":[0.000084317784,0.00011672196,0.000083414714,0.00013802703,0.00004723885,0.000041808704,0.000017636725,0.00016997135,0.000036906073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055403827,0.00037732263,0.00044451535,0.00010087639,0.000050203507,0.0000073717797,0.000025765768,0.000012843233,0.9972486,0.00027506627,0.0006596797,0.00024372053],"study_design_scores_gemma":[0.0020325466,0.00055027555,0.0029283445,0.00021618675,0.00002355996,0.0000013748262,0.000009641669,0.000075442054,0.96818113,0.000019153931,0.025858356,0.000103963226],"about_ca_topic_score_codex":0.000022767275,"about_ca_topic_score_gemma":2.537649e-7,"teacher_disagreement_score":0.029067442,"about_ca_system_score_codex":0.00014856509,"about_ca_system_score_gemma":0.00014232106,"threshold_uncertainty_score":0.4759783},"labels":[],"label_agreement":null},{"id":"W1963495389","doi":"10.4161/auto.19738","title":"Autophagy is active in normal colon mucosa","year":2012,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"BECN1; Autophagy; Biology; Intestinal mucosa; Epithelium; Colorectal cancer; Cell biology; Cell; Cancer research; Cancer; Internal medicine; Apoptosis; Medicine; Biochemistry","score_opus":0.015029201041134704,"score_gpt":0.30071207411332285,"score_spread":0.28568287307218815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1963495389","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9784114,0.002382643,0.00003507753,0.0005865798,0.0005480925,0.0004580293,0.000024467656,0.00016346097,0.01739025],"genre_scores_gemma":[0.99083585,0.00011888153,0.00026360468,0.004676532,0.0005152628,0.000077836834,0.000038566883,0.00004767444,0.0034257767],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.998134,0.000072218376,0.00035335642,0.00031681525,0.00034423635,0.00077934796],"domain_scores_gemma":[0.9989209,0.000080214224,0.00010219469,0.00045553295,0.00005661292,0.000384525],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00021974779,0.00027254637,0.00044207898,0.00021909022,0.000080568774,0.00001461675,0.00014788323,0.00022087837,0.003497705],"category_scores_gemma":[0.000049819577,0.000251929,0.00017583958,0.00038322702,0.00009537858,0.00038416297,0.00006604602,0.0003472654,0.00094150554],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008565348,0.016383652,0.22190039,0.0008313075,0.0023033144,0.0037930019,0.048892073,0.000030905878,0.18971445,0.029583896,0.056834765,0.4211669],"study_design_scores_gemma":[0.003587876,0.0002803667,0.64479387,0.000057462472,0.000090060814,0.000120133824,0.0001877546,0.00023099707,0.31343576,0.00037479773,0.036534317,0.00030659753],"about_ca_topic_score_codex":0.0001245157,"about_ca_topic_score_gemma":0.000007986492,"teacher_disagreement_score":0.4228935,"about_ca_system_score_codex":0.00018912212,"about_ca_system_score_gemma":0.00016592487,"threshold_uncertainty_score":0.9999933},"labels":[],"label_agreement":null},{"id":"W1964724793","doi":"10.4161/auto.7.5.15056","title":"Direct and indirect effects of the pRb tumor suppressor on autophagy","year":2011,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Autophagy; Myogenesis; Biology; Cell biology; Suppressor; Cell cycle; Programmed cell death; Intracellular; Cancer research; Myocyte; Cell; Cancer; Apoptosis; Genetics","score_opus":0.013542954088426257,"score_gpt":0.23758623451770272,"score_spread":0.22404328042927646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964724793","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9738195,0.0018491343,0.000004483336,0.000059472357,0.00047325098,0.0007078607,0.000011926977,0.00012273838,0.022951657],"genre_scores_gemma":[0.9967653,0.000047404123,0.000103787126,0.0012082974,0.00009801901,0.00006421632,0.0000030225028,0.00004217709,0.0016677438],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99863404,0.00012691214,0.0002738408,0.00034484718,0.0003084249,0.00031196207],"domain_scores_gemma":[0.99877715,0.00020985531,0.00015497896,0.00064883573,0.00004812932,0.00016107033],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014084255,0.00024549192,0.00047063988,0.00010325138,0.000098602824,0.000008632727,0.00020115006,0.00009645093,0.0003024459],"category_scores_gemma":[0.00017864113,0.00015710648,0.00018537708,0.00021719781,0.00021861818,0.000066185974,0.00008286917,0.00018839906,0.000039881787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00529118,0.007887863,0.027040131,0.0040160674,0.0035143115,0.0033290044,0.02161482,0.0000069904654,0.84574586,0.02309275,0.00917338,0.049287647],"study_design_scores_gemma":[0.0013103146,0.00046920613,0.3312503,0.00016129416,0.0001386482,0.00003590692,0.0000138313935,0.00002361317,0.66526246,0.00049782504,0.0007308317,0.0001057667],"about_ca_topic_score_codex":0.00005231413,"about_ca_topic_score_gemma":0.0000019939368,"teacher_disagreement_score":0.30421016,"about_ca_system_score_codex":0.000029206407,"about_ca_system_score_gemma":0.000097445605,"threshold_uncertainty_score":0.64066166},"labels":[],"label_agreement":null},{"id":"W1964853412","doi":"10.1101/pdb.prot080341","title":"Monitoring Autophagy in <i>Drosophila</i> Using Fluorescent Reporters in the UAS-GAL4 System","year":2014,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"mCherry; ATG8; Autophagy; Green fluorescent protein; Cell biology; Autophagosome; Chemistry; Biology; Biochemistry; Gene","score_opus":0.03340002596848815,"score_gpt":0.3144122082435635,"score_spread":0.2810121822750753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964853412","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9459755,0.00016410607,0.0001757992,0.00011429208,0.00018391242,0.052835643,0.0000010883139,0.00014904866,0.00040060352],"genre_scores_gemma":[0.95627135,0.0000028564639,0.0005366384,0.00025769722,0.00048144136,0.042393833,2.1807867e-7,0.00004698213,0.000008990072],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99779856,0.00018839391,0.0006416324,0.00042583875,0.00047131022,0.0004742507],"domain_scores_gemma":[0.9987117,0.00007341129,0.00020442069,0.000828691,0.000051120143,0.00013065634],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011805976,0.00024600702,0.00043910262,0.00017523646,0.00009789972,0.00007378914,0.00028363665,0.00012267218,0.0000057793027],"category_scores_gemma":[0.000100640325,0.00019546931,0.000121084195,0.00037171264,0.000051695642,0.00011509212,0.00005592889,0.00038414114,0.000014781483],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007143271,0.0010556171,0.61437374,0.0023798482,0.00010038482,0.0024724049,0.00076775445,0.00047597816,0.36424518,0.01222008,0.000027733515,0.0011669814],"study_design_scores_gemma":[0.0053435676,0.00028195346,0.7636107,0.0069365674,0.000056754823,0.000033290547,0.00013401353,0.008104666,0.2113286,0.000042475836,0.0036958696,0.0004315436],"about_ca_topic_score_codex":0.00011556963,"about_ca_topic_score_gemma":0.0000020819164,"teacher_disagreement_score":0.15291657,"about_ca_system_score_codex":0.00037561773,"about_ca_system_score_gemma":0.00014244801,"threshold_uncertainty_score":0.7971008},"labels":[],"label_agreement":null},{"id":"W1965661521","doi":"10.1091/mbc.e13-07-0381","title":"ER exit sites are physical and functional core autophagosome biogenesis components","year":2013,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":386,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Regina","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Jane Coffin Childs Memorial Fund for Medical Research","keywords":"Endoplasmic reticulum; Autophagy; Cell biology; Biology; Biogenesis; COPII; Autophagosome; Vacuole; Lysosome; Organelle biogenesis; Cytoplasm; Golgi apparatus; Secretory pathway; Biochemistry; Enzyme","score_opus":0.02070618594517461,"score_gpt":0.2559309639293501,"score_spread":0.2352247779841755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965661521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971781,0.0014651292,0.00006611111,0.0006998167,0.000082785715,0.00022352928,0.00001834612,0.000017807952,0.00024842127],"genre_scores_gemma":[0.99843645,0.000029018638,0.000090871334,0.000951551,0.00006491652,0.000015470878,0.000041624557,0.000011580491,0.00035854237],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99946797,0.000043701184,0.00010378159,0.00017162354,0.000081563565,0.00013133336],"domain_scores_gemma":[0.9995387,0.000027229287,0.00007705125,0.00024270568,0.000048399903,0.0000659152],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000027131277,0.00010965352,0.00020228463,0.000050931325,0.000047629008,0.0000030385986,0.00007939153,0.00007874162,0.00020946158],"category_scores_gemma":[0.000008628034,0.000069189686,0.00012683526,0.000091587375,0.00025042027,0.000013306482,0.000070907474,0.00007074819,0.00007049642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038918817,0.00018761838,0.035299964,0.000025757772,0.00008793875,0.0000055480214,0.000024505778,0.0000022684578,0.9632927,0.00015084338,0.0007292771,0.00015465869],"study_design_scores_gemma":[0.0006951958,0.00009017271,0.34664702,0.000013204136,0.000071928465,0.00000953014,0.000013883234,0.00019338656,0.6488439,0.0030579853,0.00029825227,0.0000655231],"about_ca_topic_score_codex":0.000017348088,"about_ca_topic_score_gemma":1.3438883e-7,"teacher_disagreement_score":0.3144488,"about_ca_system_score_codex":0.0000065208187,"about_ca_system_score_gemma":0.000013243266,"threshold_uncertainty_score":0.28214735},"labels":[],"label_agreement":null},{"id":"W1967809393","doi":"10.4161/auto.5269","title":"Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila","year":2008,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":709,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Autophagy; Biology; Neurodegeneration; Cell biology; Oxidative stress; Senescence; Longevity; Ageing; Gene expression; Ubiquitin; Gene; Genetics; Biochemistry; Internal medicine; Apoptosis","score_opus":0.019638835092534508,"score_gpt":0.26463422405662745,"score_spread":0.24499538896409295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967809393","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928717,0.0042586215,0.000019092928,0.0004985783,0.00010343946,0.00067145185,0.000017596196,0.00006096181,0.0014985338],"genre_scores_gemma":[0.9986156,0.00021491376,0.00029995266,0.00043024088,0.00011451273,0.0000729593,0.000004327434,0.000026815309,0.00022064631],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99784523,0.00023886908,0.0006505395,0.00042418903,0.000442835,0.00039830577],"domain_scores_gemma":[0.99891645,0.00020274363,0.00021996775,0.0004760999,0.0000884185,0.00009631465],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005681389,0.0002484022,0.00059738045,0.00016398783,0.00010535199,0.000012960807,0.00022834844,0.0001361832,0.000024230982],"category_scores_gemma":[0.00014055161,0.00018193565,0.00009621138,0.00047167332,0.00025058124,0.00014718193,0.00004582358,0.0003025065,0.000007930853],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00476564,0.006901565,0.14745444,0.013576519,0.0007613255,0.044279262,0.15965247,0.00006227331,0.52585727,0.06441213,0.0007322277,0.031544864],"study_design_scores_gemma":[0.0023812163,0.00020226878,0.90396345,0.0008174681,0.000035070963,0.00026705037,0.00045786548,0.0006637094,0.09027102,0.00068792736,0.00005473593,0.00019822012],"about_ca_topic_score_codex":0.00013291599,"about_ca_topic_score_gemma":0.00013027151,"teacher_disagreement_score":0.756509,"about_ca_system_score_codex":0.00008843795,"about_ca_system_score_gemma":0.0001724323,"threshold_uncertainty_score":0.74191207},"labels":[],"label_agreement":null},{"id":"W1967874462","doi":"10.1111/j.1474-9726.2007.00294.x","title":"Oxidative stress and aberrant signaling in aging and cognitive decline","year":2007,"lang":"en","type":"review","venue":"Aging Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":479,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Oxidative stress; Biology; Insulin receptor; Neurodegeneration; Reactive oxygen species; Cell biology; DNA damage; Oxidative phosphorylation; Signal transduction; Autophagy; Insulin; Sirtuin; Lipid peroxidation; Endocrinology; Internal medicine; Biochemistry; Insulin resistance; Apoptosis; Medicine; Acetylation","score_opus":0.04198873805007155,"score_gpt":0.36348723694455176,"score_spread":0.32149849889448023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967874462","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.019489344,0.97874796,0.00009801832,0.000017744813,0.000055771023,0.0005862526,0.000030539464,0.000031623455,0.00094271643],"genre_scores_gemma":[0.027386365,0.9715746,0.00014614014,0.00028508692,0.0001681682,0.000017404449,0.00013583573,0.00005248482,0.00023390236],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986032,0.00008742489,0.00040820675,0.00043496038,0.00016672949,0.00029946954],"domain_scores_gemma":[0.99894106,0.0005329484,0.00018924211,0.00013631443,0.00004284468,0.00015758701],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033385033,0.00033746267,0.0010710018,0.0002827246,0.000055277807,0.000028591629,0.00005812838,0.00015891956,0.000040122904],"category_scores_gemma":[0.000031447886,0.00027802194,0.00010742497,0.00020638887,0.00009800296,0.000053230542,0.000080645375,0.0004773322,0.000008686139],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026546042,0.00012859672,0.0013300139,0.016171617,0.00020826583,0.00089172064,0.0009254073,1.7494001e-7,0.000026307445,0.000008277738,0.0000064945325,0.9802766],"study_design_scores_gemma":[0.01295074,0.0005851463,0.0035853265,0.46614882,0.011360871,0.00045729897,0.0032994512,0.00013899535,0.0065611717,0.0005080622,0.49140057,0.003003537],"about_ca_topic_score_codex":0.000052616837,"about_ca_topic_score_gemma":0.000008690599,"teacher_disagreement_score":0.97727305,"about_ca_system_score_codex":0.000037229656,"about_ca_system_score_gemma":0.00011047492,"threshold_uncertainty_score":0.9999672},"labels":[],"label_agreement":null},{"id":"W1968255867","doi":"10.1371/journal.pone.0006068","title":"A Genetic Screen in Drosophila Reveals Novel Cytoprotective Functions of the Autophagy-Lysosome Pathway","year":2009,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Institute of General Medical Sciences; National Institutes of Health; American Cancer Society","keywords":"Autophagy; Lysosome; Biology; Cell biology; Genetic screen; Neurodegeneration; Autophagy-related protein 13; BAG3; ATG16L1; Programmed cell death; Schneider 2 cells; Gene; Genetics; Phenotype; RNA interference; Signal transduction; Biochemistry; RNA; Apoptosis","score_opus":0.03514962700772765,"score_gpt":0.2404545658999163,"score_spread":0.20530493889218865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968255867","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949562,0.00079049345,0.000064198364,0.001093819,0.000020627174,0.0010009098,0.000044467783,0.00004428936,0.0019850142],"genre_scores_gemma":[0.9967808,0.00004973337,0.0008508425,0.0010436447,0.00015606162,0.00005063919,0.0000057469438,0.000016817869,0.0010457247],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988987,0.00003547715,0.0002838382,0.0002224328,0.00035320813,0.00020636828],"domain_scores_gemma":[0.9991932,0.000028640748,0.00009859261,0.00048679102,0.00009796058,0.00009480133],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009189563,0.00013305395,0.00035644035,0.00010736126,0.00005619057,0.0000053475296,0.000105625666,0.00009711836,0.00009877773],"category_scores_gemma":[0.00008752941,0.00009854018,0.00013208567,0.0004023906,0.000070307404,0.000049563685,0.000024098823,0.00022781132,0.000027825596],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002999012,0.0051714177,0.0134724,0.00007604895,0.00028720903,0.000029638713,0.00021696796,0.00001052473,0.97883505,0.0005318273,0.00001560784,0.0010533854],"study_design_scores_gemma":[0.0017683051,0.0005146137,0.85581404,0.00046456826,0.00018795727,0.000010999031,0.000021399761,0.00018991974,0.13909258,0.001835861,0.000010763381,0.00008901685],"about_ca_topic_score_codex":0.000025531834,"about_ca_topic_score_gemma":0.0000027879303,"teacher_disagreement_score":0.8423416,"about_ca_system_score_codex":0.00007119102,"about_ca_system_score_gemma":0.00013841868,"threshold_uncertainty_score":0.4018352},"labels":[],"label_agreement":null},{"id":"W1968347386","doi":"10.4161/auto.25413","title":"Genome-wide RNAi screen identifies ATPase inhibitory factor 1 (ATPIF1) as essential for PARK2 recruitment and mitophagy","year":2013,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario; Montreal Neurological Institute and Hospital; University of Ottawa","funders":"Canada Research Chairs; Parkinson Society Canada; Michael J. Fox Foundation for Parkinson's Research","keywords":"Mitophagy; PINK1; Biology; Parkin; Cell biology; Mitochondrion; Autophagy; Genetics; Parkinson's disease","score_opus":0.02875612833121057,"score_gpt":0.3035916879474496,"score_spread":0.27483555961623907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968347386","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9884951,0.0057211756,0.00032384737,0.0007134803,0.0006066761,0.0030470178,0.00007369988,0.0002242129,0.00079480093],"genre_scores_gemma":[0.98724204,0.0004049607,0.00050324143,0.0025332673,0.0008738041,0.0009508099,0.0001459125,0.00009063865,0.0072553502],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99774957,0.00007148191,0.0005356315,0.0006471213,0.00039289508,0.0006033136],"domain_scores_gemma":[0.9983657,0.00022618935,0.00017895775,0.00056846143,0.0001943318,0.0004663309],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014668217,0.0003992477,0.00056689704,0.00018617195,0.0002411654,0.00013198056,0.0001807917,0.00021616378,0.0020122284],"category_scores_gemma":[0.0001359154,0.0003538018,0.00027223548,0.00013822163,0.00021177459,0.00035919773,0.00010995629,0.00019724091,0.0005396499],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017653372,0.0018942753,0.01230747,0.0010616686,0.002522005,0.00072069,0.003429884,0.0000071563927,0.892325,0.0014169166,0.025636444,0.05691319],"study_design_scores_gemma":[0.0064837052,0.0009136478,0.38990703,0.00013821809,0.00029977158,0.00007971334,0.0003226957,0.00014505611,0.55877197,0.0037785901,0.03849669,0.000662879],"about_ca_topic_score_codex":0.00027416187,"about_ca_topic_score_gemma":0.0000109139355,"teacher_disagreement_score":0.37759957,"about_ca_system_score_codex":0.00009578511,"about_ca_system_score_gemma":0.00018422381,"threshold_uncertainty_score":0.9998914},"labels":[],"label_agreement":null},{"id":"W1969756521","doi":"10.1016/j.immuni.2013.10.013","title":"The Protein ATG16L1 Suppresses Inflammatory Cytokines Induced by the Intracellular Sensors Nod1 and Nod2 in an Autophagy-Independent Manner","year":2013,"lang":"en","type":"article","venue":"Immunity","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":191,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"ATG16L1; Autophagy; NOD2; Biology; Intracellular; Proinflammatory cytokine; NOD1; Cell biology; ULK1; Inflammation; Lipopolysaccharide; Tumor necrosis factor alpha; Immunology; Innate immune system; Immune system; Biochemistry; Phosphorylation; Protein kinase A; Apoptosis","score_opus":0.011363224270484725,"score_gpt":0.2511460951190376,"score_spread":0.2397828708485529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1969756521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99479514,0.0022046224,0.0000019699462,0.0013946955,0.00008411232,0.0012518939,0.000004977759,0.000067208544,0.00019537643],"genre_scores_gemma":[0.99846065,0.00010570273,0.00001264675,0.00026389983,0.00008688233,0.0002257861,0.000017471632,0.00003135633,0.00079560565],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984777,0.00038975212,0.00031170598,0.00020922913,0.00027660956,0.00033500337],"domain_scores_gemma":[0.9987352,0.00012637902,0.00010139206,0.0007960888,0.00010497174,0.00013596067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047190292,0.00021851575,0.00022369972,0.000051412466,0.00037520274,0.00012185925,0.0003012892,0.00014800903,0.00017713601],"category_scores_gemma":[0.00010159056,0.0001222156,0.000054417098,0.0001049177,0.00023292711,0.0002551136,0.000114463226,0.00061631843,0.000044952118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002505897,0.00032087945,0.0059350724,0.000063872045,0.0001134108,0.000048980342,0.001953615,0.0000038777393,0.9818277,0.0002765351,0.0003413355,0.008864149],"study_design_scores_gemma":[0.002083582,0.00023306142,0.41355702,0.000109566485,0.000048980415,0.000040297353,0.0017942874,0.00053411355,0.57672215,0.00091012946,0.003688019,0.0002788073],"about_ca_topic_score_codex":0.0008440102,"about_ca_topic_score_gemma":0.00012107849,"teacher_disagreement_score":0.40762195,"about_ca_system_score_codex":0.000043172276,"about_ca_system_score_gemma":0.00007537037,"threshold_uncertainty_score":0.49838072},"labels":[],"label_agreement":null},{"id":"W1969890668","doi":"10.1523/jneurosci.2061-10.2010","title":"Autophagy-Dependent Rhodopsin Degradation Prevents Retinal Degeneration in<i>Drosophila</i>","year":2010,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Rhodopsin; Autophagy; Retinal degeneration; Cell biology; Endosome; Retinitis pigmentosa; Biology; Lysosome; Retinal; Gene knockdown; Lipofuscin; Biochemistry; Intracellular; Gene","score_opus":0.023537123182201185,"score_gpt":0.3030052975430335,"score_spread":0.2794681743608323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1969890668","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972177,0.00007503032,0.00042057433,0.0006920036,0.0012526887,0.000121024066,0.0000014359057,0.000009542324,0.00021000649],"genre_scores_gemma":[0.99728703,0.00007583148,0.0010357697,0.0009452956,0.0002814123,0.0000019026326,8.92785e-7,0.000008941974,0.00036293207],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99869096,0.000052686555,0.00039944195,0.00015803971,0.00053682306,0.00016207328],"domain_scores_gemma":[0.9992673,0.000025752744,0.00028272506,0.00016648501,0.00010284702,0.00015492387],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004847609,0.00009232132,0.00016744946,0.00017004354,0.00006563529,0.00003706194,0.00017490763,0.000053025524,0.00003112558],"category_scores_gemma":[0.00026271777,0.00007412844,0.00007516525,0.00025541396,0.000074824915,0.00035744932,0.000019395131,0.0004042723,0.0000046583145],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011040151,0.00022280564,0.0076433457,0.0000070663145,0.0000013132751,0.00023949337,0.000044621036,0.000036693174,0.9895396,0.00020442747,0.00007340528,0.0018768104],"study_design_scores_gemma":[0.0016075858,0.00060602714,0.53790647,0.00006530576,0.000029749881,0.0016541611,0.000011376417,0.0011547505,0.45514575,0.00081189553,0.00090372737,0.00010318933],"about_ca_topic_score_codex":0.0000023768641,"about_ca_topic_score_gemma":0.0000037942598,"teacher_disagreement_score":0.53439385,"about_ca_system_score_codex":0.000034657776,"about_ca_system_score_gemma":0.00022380831,"threshold_uncertainty_score":0.302287},"labels":[],"label_agreement":null},{"id":"W1970110195","doi":"10.1007/s00401-012-1073-6","title":"VMA21 deficiency prevents vacuolar ATPase assembly and causes autophagic vacuolar myopathy","year":2013,"lang":"en","type":"article","venue":"Acta Neuropathologica","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":138,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; Vacuole; Biology; Myopathy; Chaperone (clinical); Cytoplasm; BAG3; mTORC1; Biochemistry; Genetics; Phosphorylation; Apoptosis","score_opus":0.015402809719525628,"score_gpt":0.2571972093371846,"score_spread":0.24179439961765897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970110195","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936293,0.0023487783,0.00003433887,0.0006580525,0.00020959081,0.00084135914,0.000017093065,0.00033060482,0.0019309212],"genre_scores_gemma":[0.99352545,0.0010116085,0.00038869356,0.0039915727,0.00012679628,0.0001005491,0.00001975944,0.000054884833,0.0007807128],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99769837,0.00026240977,0.0003965523,0.000715502,0.00035738244,0.00056978874],"domain_scores_gemma":[0.998523,0.00013128802,0.00016044141,0.0006921546,0.00010628077,0.00038686045],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023930366,0.0003799441,0.00047501206,0.00013469877,0.00024207337,0.000090036076,0.00025446597,0.00017286553,0.0006511249],"category_scores_gemma":[0.00031317194,0.00028350824,0.00015182329,0.00026425582,0.00015629981,0.00033227546,0.0001833361,0.0003834515,0.00039936352],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021920366,0.002002229,0.06344039,0.00021552446,0.000074487994,0.0061193816,0.00060831476,0.0000018109273,0.91049737,0.00040820034,0.0034619276,0.01295119],"study_design_scores_gemma":[0.0016866266,0.0015600557,0.9662467,0.00006346932,0.00020995474,0.0011702022,0.00008281119,0.00015294373,0.024718897,0.00075404457,0.0029290724,0.00042517998],"about_ca_topic_score_codex":0.000015463747,"about_ca_topic_score_gemma":2.8455247e-7,"teacher_disagreement_score":0.90280634,"about_ca_system_score_codex":0.000028702618,"about_ca_system_score_gemma":0.00007043846,"threshold_uncertainty_score":0.99996173},"labels":[],"label_agreement":null},{"id":"W1970165340","doi":"10.1074/jbc.m113.542795","title":"p27 Protein Protects Metabolically Stressed Cardiomyocytes from Apoptosis by Promoting Autophagy","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Heart and Stroke Foundation; University of Toronto; University Health Network; Toronto General Hospital","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Autophagy; ATG5; Apoptosis; Cell biology; Bafilomycin; In vivo; Biology; Gene knockdown; ATG12; In vitro; Chemistry; Biochemistry","score_opus":0.012345412556625586,"score_gpt":0.24764490741875414,"score_spread":0.23529949486212856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970165340","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99622595,0.0015689712,0.00043639244,0.00065298483,0.000044955905,0.00027133667,0.00002609337,0.000051122297,0.00072221423],"genre_scores_gemma":[0.997362,0.000053288735,0.0011714448,0.00031254458,0.0008757134,0.00002603794,0.000028107072,0.000016572749,0.00015427115],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983792,0.00013542279,0.00059236254,0.00026092312,0.00035016792,0.0002819807],"domain_scores_gemma":[0.99860424,0.00012067631,0.0004767485,0.00024634678,0.00018699364,0.0003650039],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051262695,0.00022520561,0.00068541255,0.000021440497,0.00006228282,0.000031166594,0.00024133919,0.00030195815,0.0005419225],"category_scores_gemma":[0.0010141988,0.00014077705,0.00036003004,0.00012629347,0.00011160574,0.000053923824,0.00004981381,0.0005308441,0.0000069642642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034570938,0.0002964996,0.00067693443,0.00005812753,0.0002652615,0.000027317457,0.000024596253,7.414993e-7,0.9885462,0.0000063708467,0.0003444179,0.009407851],"study_design_scores_gemma":[0.0016212483,0.00040885416,0.002389821,0.00018668995,0.00009794902,0.000040771105,0.00002439845,0.00008169761,0.98968047,0.0005886828,0.0047248728,0.00015454093],"about_ca_topic_score_codex":0.000007159573,"about_ca_topic_score_gemma":2.580758e-8,"teacher_disagreement_score":0.00925331,"about_ca_system_score_codex":0.000044817403,"about_ca_system_score_gemma":0.00008937348,"threshold_uncertainty_score":0.59336716},"labels":[],"label_agreement":null},{"id":"W1970188754","doi":"10.4161/auto.5.5.8091","title":"Tap42-associated protein phosphatase type 2A negatively regulates induction of autophagy","year":2009,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institutes of Health; University of Victoria","keywords":"Autophagy; Biology; Cell biology; Protein phosphatase 2; BAG3; Autophagy-related protein 13; Protein subunit; Phosphatase; Mutant; ULK1; Protein kinase A; Phosphorylation; Biochemistry; Gene; Protein phosphorylation; Apoptosis","score_opus":0.015582078176548235,"score_gpt":0.2776493773452805,"score_spread":0.2620672991687323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970188754","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993318,0.0031072204,0.000028861376,0.00052950846,0.00023841712,0.0007735428,0.00003317806,0.00027364152,0.0016975945],"genre_scores_gemma":[0.99464965,0.00007406471,0.00053467567,0.0007404182,0.00015413045,0.000021357913,0.00016843501,0.00003602428,0.0036212613],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99814767,0.00009374856,0.00052080833,0.00040397735,0.0004275887,0.0004062112],"domain_scores_gemma":[0.99862456,0.000040533512,0.00033021695,0.0004933708,0.00030016582,0.00021116257],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002377268,0.00029158907,0.00055898365,0.00017438886,0.000106593834,0.000017969583,0.00016454651,0.00025357067,0.0007463847],"category_scores_gemma":[0.0002692903,0.0002622167,0.00017976695,0.00070758205,0.00013461802,0.00022121899,0.000026131615,0.00026390312,0.00010478824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025130678,0.003667243,0.00068563496,0.00016686982,0.0008670655,0.0005035203,0.001353957,0.000049631126,0.8655528,0.021712476,0.0062471475,0.0966806],"study_design_scores_gemma":[0.0027571688,0.0014376938,0.17107405,0.0001866893,0.00013243858,0.00002383979,0.0000476712,0.00029224457,0.8166164,0.005776751,0.0014228808,0.00023214529],"about_ca_topic_score_codex":0.00007334185,"about_ca_topic_score_gemma":0.0000018632066,"teacher_disagreement_score":0.17038842,"about_ca_system_score_codex":0.0001253345,"about_ca_system_score_gemma":0.00027007153,"threshold_uncertainty_score":0.999983},"labels":[],"label_agreement":null},{"id":"W1970285863","doi":"10.4161/auto.24921","title":"Dual inhibition of autophagy and the AKT pathway in prostate cancer","year":2013,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"PI3K/AKT/mTOR pathway; Autophagy; Protein kinase B; DU145; Cancer research; Prostate cancer; Biology; PTEN; Apoptosis; Cancer; Signal transduction; LNCaP; Cell biology","score_opus":0.007468352581998973,"score_gpt":0.24980772862847436,"score_spread":0.2423393760464754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970285863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99107647,0.0049006417,0.000006250782,0.001588403,0.000115244504,0.00091608096,0.00001471831,0.000045039516,0.0013371422],"genre_scores_gemma":[0.9965091,0.0004504247,0.00006075404,0.0011837871,0.0000941247,0.00030711826,0.000012758072,0.000021673899,0.001360274],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988835,0.00008200415,0.00035117322,0.00022443861,0.00021278014,0.00024608866],"domain_scores_gemma":[0.9993638,0.00009077293,0.00011843797,0.000253493,0.00008274398,0.000090788206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020971047,0.00015364747,0.00034937813,0.00009677638,0.000047683723,0.000017384247,0.000047315745,0.00007120233,0.00069536304],"category_scores_gemma":[0.00004114398,0.00009820861,0.00007589434,0.00020603059,0.0002958448,0.00014684477,0.000043248765,0.00016729644,0.000038651717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004690703,0.0022484367,0.028788071,0.0013788762,0.00092019455,0.001060675,0.024745187,0.00011988623,0.46284935,0.07783024,0.0057338006,0.3896346],"study_design_scores_gemma":[0.018458001,0.0003570736,0.4660578,0.00034406624,0.00008407857,0.000084472165,0.00044121282,0.0017367599,0.49539077,0.014737137,0.0020127099,0.00029590403],"about_ca_topic_score_codex":0.0010502572,"about_ca_topic_score_gemma":0.000026910757,"teacher_disagreement_score":0.43726972,"about_ca_system_score_codex":0.00003680711,"about_ca_system_score_gemma":0.00013361592,"threshold_uncertainty_score":0.76137376},"labels":[],"label_agreement":null},{"id":"W1970428129","doi":"10.4161/auto.7.1.13840","title":"Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase","year":2010,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; McGill University; University of Toronto; Hospital for Sick Children","funders":"National Institute of General Medical Sciences; Biotechnology and Biological Sciences Research Council; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; Endoplasmic reticulum; Biology; Autophagosome; Golgi apparatus; ATG16L1; GTPase; ATG8; Cytoplasm; Phagosome; BAG3; Small GTPase; Biochemistry; Signal transduction; Intracellular; Apoptosis","score_opus":0.005682605973062273,"score_gpt":0.24486878944510793,"score_spread":0.23918618347204565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970428129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99369735,0.0005417212,0.000011104836,0.00063643645,0.0017090731,0.0006230728,0.000057106052,0.00013037099,0.0025937792],"genre_scores_gemma":[0.9961315,0.00015459566,0.00029425794,0.0008512272,0.0004346837,0.00002818424,0.000029532841,0.00005347274,0.002022567],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979459,0.00011298941,0.00053282635,0.0004908894,0.00043832636,0.00047906378],"domain_scores_gemma":[0.9981385,0.00016899552,0.0002928642,0.0010121958,0.000105718835,0.0002817548],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00027690592,0.0003383336,0.00057460374,0.00011169948,0.00024277852,0.000029693854,0.00029726184,0.00027111784,0.0010486764],"category_scores_gemma":[0.00025382254,0.00023569282,0.00026290465,0.00026988366,0.00068654935,0.00013568443,0.00023506326,0.00041378158,0.00005275415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058535393,0.0002806473,0.007470187,0.00010362124,0.00017417452,0.00014596828,0.0004987194,7.2788464e-7,0.9823419,0.0059242025,0.0010449409,0.00142959],"study_design_scores_gemma":[0.004336655,0.0002666451,0.30110577,0.000056645298,0.00024250406,0.0003526559,0.000037776997,0.00014092014,0.6829055,0.0011911897,0.009119107,0.00024462622],"about_ca_topic_score_codex":0.00006437568,"about_ca_topic_score_gemma":0.00004033934,"teacher_disagreement_score":0.29943636,"about_ca_system_score_codex":0.000042076128,"about_ca_system_score_gemma":0.0002238415,"threshold_uncertainty_score":0.9998645},"labels":[],"label_agreement":null},{"id":"W1970598278","doi":"10.1111/j.1471-4159.2009.06007.x","title":"HO‐1‐mediated macroautophagy: a mechanism for unregulated iron deposition in aging and degenerating neural tissues","year":2009,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":110,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"McGill University; American Academy of Neurology","keywords":"Mechanism (biology); Autophagy; Chemistry; Cell biology; Neuroscience; Biology; Biochemistry","score_opus":0.010145292223670593,"score_gpt":0.27773433790994645,"score_spread":0.26758904568627584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970598278","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974334,0.0011031448,0.00027514136,0.00095494813,0.00006103735,0.00011364894,0.0000028603786,0.000019078643,0.000036711444],"genre_scores_gemma":[0.9974932,0.00012398975,0.0010294564,0.0010138723,0.00026412262,0.0000020250236,0.00001203915,0.000014252486,0.000047063215],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917436,0.000020763573,0.00035190434,0.0001306144,0.00015491951,0.00016744735],"domain_scores_gemma":[0.9994291,0.000046403005,0.00020533393,0.000083260245,0.00010664635,0.0001292597],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000096730895,0.0001238196,0.00024389283,0.00007182753,0.000045414028,0.000024936275,0.000055166114,0.00007971973,0.000007931592],"category_scores_gemma":[0.00009674909,0.00011135908,0.00007474226,0.00009135918,0.000016259286,0.000090626185,0.0000075877206,0.00020146911,2.2947661e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024002761,0.000094870455,0.0002653145,0.00006827121,0.000015276859,0.00047255916,0.0001012065,0.000022499122,0.99433434,0.000017607696,0.000041289062,0.004326747],"study_design_scores_gemma":[0.0034227034,0.0005478962,0.02180981,0.0002447041,0.000091347785,0.0016470425,0.000061747785,0.008566972,0.96293324,0.0005398148,0.000012130167,0.00012257077],"about_ca_topic_score_codex":0.0000011723644,"about_ca_topic_score_gemma":2.4556715e-7,"teacher_disagreement_score":0.03140107,"about_ca_system_score_codex":0.000033305514,"about_ca_system_score_gemma":0.000043671127,"threshold_uncertainty_score":0.45410913},"labels":[],"label_agreement":null},{"id":"W1970661950","doi":"10.1038/nrm3565","title":"Signals from the lysosome: a control centre for cellular clearance and energy metabolism","year":2013,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1676,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Neurological Disorders and Stroke","keywords":"TFEB; Autophagy; Lysosome; Cell biology; Biogenesis; Biology; Transcription factor; Regulator; Biochemistry; Gene","score_opus":0.014832632117960336,"score_gpt":0.30079655510800024,"score_spread":0.2859639229900399,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970661950","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000012376391,0.9940136,0.0011672003,0.00033363927,0.0003860506,0.0034033407,0.0003422578,0.000034603443,0.00030691933],"genre_scores_gemma":[0.00010679429,0.98907757,0.0004950818,0.0070358384,0.00074811705,0.0007766368,0.0011070259,0.00010832191,0.0005446027],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99633825,0.0011599845,0.00092099025,0.0009163519,0.0001483636,0.00051604083],"domain_scores_gemma":[0.99734133,0.000546051,0.0007512581,0.0009999368,0.00012679856,0.00023461902],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00039839925,0.00080628216,0.0041289455,0.000086312866,0.000097087854,0.00003171966,0.000452528,0.0017403952,0.00023496718],"category_scores_gemma":[0.0001839726,0.0004233679,0.0016678246,0.00022378385,0.00017108179,0.000026411284,0.00006977486,0.0010222909,0.00008427193],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043017342,0.00006692344,6.054374e-7,0.004458187,0.00077462033,0.00003262705,0.00001036359,4.305818e-8,0.0015892681,0.0013150885,0.0037337733,0.9879755],"study_design_scores_gemma":[0.0012326584,0.00007190463,7.567109e-7,0.0032640973,0.005346516,0.0000103899565,0.0000021174853,0.000007631996,0.00046271938,0.0005225339,0.9886937,0.00038497688],"about_ca_topic_score_codex":0.000018991715,"about_ca_topic_score_gemma":9.694213e-7,"teacher_disagreement_score":0.9875905,"about_ca_system_score_codex":0.00003383109,"about_ca_system_score_gemma":0.00018107024,"threshold_uncertainty_score":0.99982184},"labels":[],"label_agreement":null},{"id":"W1971280995","doi":"10.4161/auto.19768","title":"Caspase activation regulates the extracellular export of autophagic vacuoles","year":2012,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Vacuole; Cell biology; Biology; Apoptosis; Lysosome; Intracellular; Caspase; Programmed cell death; Cytoplasm; Biochemistry","score_opus":0.02118460679519844,"score_gpt":0.2786958341620992,"score_spread":0.25751122736690074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971280995","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887794,0.00800813,0.00031957877,0.0004497452,0.00024067458,0.00038548233,0.000005079648,0.0001064685,0.0017054427],"genre_scores_gemma":[0.99529374,0.00008739579,0.00030046914,0.00044014267,0.000391087,0.000036524438,0.000033572866,0.000034183144,0.0033828628],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986952,0.00006562141,0.00035769274,0.00018369741,0.00033991577,0.000357901],"domain_scores_gemma":[0.9988506,0.00011132117,0.00019342086,0.00059602485,0.00008245995,0.00016617899],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00034187653,0.00019022057,0.0002967784,0.00008611804,0.00011032232,0.000009666798,0.00013972,0.00011756743,0.0009433335],"category_scores_gemma":[0.00006492226,0.00012620067,0.00017832608,0.0002288682,0.00019173181,0.00021811972,0.000036717036,0.00016188195,0.000082984654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005328146,0.0020127404,0.017283525,0.00028569883,0.0007293823,0.00011859275,0.004438695,0.000028335427,0.8908269,0.039004155,0.004082019,0.040657174],"study_design_scores_gemma":[0.00082249864,0.000106265165,0.2171102,0.000052759016,0.0001408817,0.00007157356,0.00020098015,0.00019667012,0.7748244,0.000791161,0.0055541336,0.00012849132],"about_ca_topic_score_codex":0.000029187086,"about_ca_topic_score_gemma":2.578589e-7,"teacher_disagreement_score":0.19982667,"about_ca_system_score_codex":0.000043556083,"about_ca_system_score_gemma":0.00009111739,"threshold_uncertainty_score":0.99996996},"labels":[],"label_agreement":null},{"id":"W1971308852","doi":"10.1074/jbc.m112.436584","title":"Lacritin Rescues Stressed Epithelia via Rapid Forkhead Box O3 (FOXO3)-associated Autophagy That Restores Metabolism","year":2013,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Cancer Institute; National Eye Institute","keywords":"Cell biology; Homeostasis; Biology; Autophagy; Apoptosis; Biochemistry","score_opus":0.02806691786871317,"score_gpt":0.27613161530275365,"score_spread":0.24806469743404047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971308852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98622596,0.010625108,0.00004268661,0.0013685202,0.00017549624,0.00017367637,0.00002617831,0.00007229677,0.0012900874],"genre_scores_gemma":[0.99552584,0.0015156673,0.00044185942,0.0009178217,0.0007927097,0.0000143339,0.000035706933,0.00002409054,0.00073199644],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980376,0.000116888834,0.000700874,0.00025973291,0.00043635583,0.00044855487],"domain_scores_gemma":[0.9981595,0.00020896259,0.00054000283,0.00029580473,0.00035597952,0.00043969683],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00041704715,0.00029099817,0.000786889,0.000051561612,0.00009776506,0.000044757133,0.00031461855,0.00045390177,0.0033964897],"category_scores_gemma":[0.0006028207,0.00018162254,0.0004842131,0.00014843482,0.00021557545,0.00013926292,0.000058373393,0.00064255245,0.00004093676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006711804,0.00082393584,0.007860332,0.0000771746,0.0005376592,0.00039144047,0.00008024109,0.0000012509928,0.97234,0.00001736439,0.009157257,0.008042183],"study_design_scores_gemma":[0.0027206417,0.00037730642,0.20249902,0.00020455816,0.00015625087,0.00020675886,0.00017763484,0.0000310766,0.7863049,0.0022979542,0.0047862427,0.0002376942],"about_ca_topic_score_codex":0.00002463283,"about_ca_topic_score_gemma":3.7095788e-7,"teacher_disagreement_score":0.19463868,"about_ca_system_score_codex":0.00009144355,"about_ca_system_score_gemma":0.00011614005,"threshold_uncertainty_score":0.99751455},"labels":[],"label_agreement":null},{"id":"W1972353600","doi":"10.1159/000358661","title":"Hepatic Lipase Release is Inhibited by a Purinergic Induction of Autophagy","year":2014,"lang":"en","type":"article","venue":"Cellular Physiology and Biochemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Government of Ontario; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Purinergic receptor; Extracellular; Cell biology; Adenosine; Purinergic signalling; Secretion; Chemistry; Biology; Molecular biology; Biochemistry; Receptor; Adenosine receptor; Apoptosis","score_opus":0.004100853209967682,"score_gpt":0.2118798298026115,"score_spread":0.20777897659264383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972353600","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978262,0.0016277406,0.000028282357,0.00013887775,0.000042953056,0.00008084015,0.000012962033,0.000031022868,0.00021108371],"genre_scores_gemma":[0.9980509,0.00013975467,0.00003602355,0.00054181507,0.00015508823,0.000009424064,0.00021583927,0.000011408232,0.0008397294],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993122,0.00003161569,0.0001816801,0.0002585507,0.00007384188,0.00014206217],"domain_scores_gemma":[0.9994551,0.000021506647,0.000095270996,0.00026665843,0.00004316846,0.00011828238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000057364716,0.00013344573,0.00025106763,0.000026625265,0.000043845062,0.0000024108103,0.000046977457,0.00019433332,0.00019211824],"category_scores_gemma":[0.000031938496,0.00011328017,0.00007402072,0.000088234396,0.00020109264,0.000020180418,0.00002736465,0.0001365979,0.00000906144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001695602,0.00021637276,0.00023001213,0.00030451835,0.000060016242,0.000006475204,0.000039690683,2.90145e-7,0.99689215,0.000023997993,0.0010781946,0.0009787261],"study_design_scores_gemma":[0.0010991399,0.00016886459,0.0012499223,0.000047411835,0.000076600074,0.000017955635,0.000018500668,0.0003387212,0.9958227,0.0004876773,0.0005681479,0.00010435394],"about_ca_topic_score_codex":0.000008903785,"about_ca_topic_score_gemma":2.107958e-8,"teacher_disagreement_score":0.001487986,"about_ca_system_score_codex":0.000009345438,"about_ca_system_score_gemma":0.000032144362,"threshold_uncertainty_score":0.46194312},"labels":[],"label_agreement":null},{"id":"W1972458464","doi":"10.1007/s10495-014-0985-0","title":"WIN induces apoptotic cell death in human colon cancer cells through a block of autophagic flux dependent on PPARγ down-regulation","year":2014,"lang":"en","type":"article","venue":"APOPTOSIS","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Autophagy; Cell biology; Endoplasmic reticulum; Gene silencing; Peroxisome proliferator-activated receptor; Programmed cell death; Apoptosis; Cancer cell; Biology; Receptor; Chemistry; Cancer research; Cancer; Biochemistry; Gene","score_opus":0.02072628438117703,"score_gpt":0.29467476953962035,"score_spread":0.27394848515844333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972458464","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99367243,0.00025907467,0.000026147267,0.00019542701,0.00018049627,0.0005221479,0.000011699441,0.000054453023,0.0050780983],"genre_scores_gemma":[0.9979421,0.00008027962,0.00015421299,0.00061486516,0.0001599161,0.00008531475,0.00003221958,0.000036280035,0.0008948474],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983632,0.00010540815,0.00042946005,0.00038075642,0.00040483073,0.0003163527],"domain_scores_gemma":[0.9991168,0.00008889636,0.00020710488,0.0004180348,0.000063528496,0.000105667044],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018406913,0.00024136822,0.00045898996,0.00015705806,0.000078813544,0.000013487881,0.00014741457,0.0001788811,0.00043632757],"category_scores_gemma":[0.000014448617,0.00021359923,0.00012565842,0.00023039557,0.000060034195,0.000092361326,0.000031858184,0.0002005044,0.00005843888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002407256,0.0010184416,0.0052668285,0.0001655897,0.000098852484,0.00000406044,0.0010153926,0.0009221388,0.9889735,0.0009443562,0.0005379224,0.0008122173],"study_design_scores_gemma":[0.0024541016,0.00055094226,0.050766136,0.00018474592,0.00015330945,9.412709e-7,0.000058273024,0.00026765608,0.94433355,0.0008115519,0.00023176013,0.00018702242],"about_ca_topic_score_codex":0.0007731291,"about_ca_topic_score_gemma":0.000033073877,"teacher_disagreement_score":0.045499306,"about_ca_system_score_codex":0.0001532669,"about_ca_system_score_gemma":0.000078303034,"threshold_uncertainty_score":0.87103236},"labels":[],"label_agreement":null},{"id":"W1972542282","doi":"10.1016/j.cellsig.2012.09.020","title":"Starvation-induced autophagy is regulated by mitochondrial reactive oxygen species leading to AMPK activation","year":2012,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":290,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"CancerCare Manitoba Foundation; Manitoba Health Research Council","keywords":"Autophagy; AMPK; Cell biology; Reactive oxygen species; Mitochondrial ROS; Chemistry; Programmed cell death; PI3K/AKT/mTOR pathway; Mitochondrion; AMP-activated protein kinase; Protein kinase A; Biology; Signal transduction; Biochemistry; Apoptosis; Kinase","score_opus":0.030219121852374457,"score_gpt":0.27195118357183123,"score_spread":0.24173206171945677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972542282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9761589,0.0003766434,0.020606315,0.00050007773,0.0004502931,0.00064129976,0.000011140538,0.0001456033,0.0011097236],"genre_scores_gemma":[0.9918236,0.000011691057,0.001132211,0.0011094856,0.0013316022,0.000034833105,0.00026479765,0.000060739014,0.0042310213],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983341,0.00005923856,0.0003479566,0.00034768452,0.00043586426,0.00047516316],"domain_scores_gemma":[0.9989542,0.000088453446,0.00015487884,0.00030461702,0.00015592345,0.00034195738],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001818756,0.00025057286,0.00033781774,0.000168594,0.00020146414,0.000044632725,0.00011506494,0.00017945025,0.0007902717],"category_scores_gemma":[0.000081094884,0.00024706026,0.00013695289,0.0003721385,0.000026610882,0.00036583992,0.000027988695,0.00023164904,0.00021595054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002946792,0.00016815176,0.00027304736,0.00002316343,0.00017656025,0.0000067430765,0.002661431,0.000019258183,0.991752,0.00022134249,0.0036156701,0.0007879144],"study_design_scores_gemma":[0.00093150407,0.00012646528,0.0016504205,0.00011900389,0.00009663647,0.0000024815872,0.00029978607,0.00031299435,0.98242074,0.00014313872,0.013641494,0.00025532037],"about_ca_topic_score_codex":0.000027343083,"about_ca_topic_score_gemma":3.0028252e-7,"teacher_disagreement_score":0.019474104,"about_ca_system_score_codex":0.00018625842,"about_ca_system_score_gemma":0.00007971084,"threshold_uncertainty_score":0.99999815},"labels":[],"label_agreement":null},{"id":"W1972995615","doi":"10.1016/j.chom.2010.07.002","title":"A Diacylglycerol-Dependent Signaling Pathway Contributes to Regulation of Antibacterial Autophagy","year":2010,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":148,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; National Institute of General Medical Sciences; Wellcome Trust","keywords":"Biology; Diacylglycerol kinase; Autophagy; Cell biology; Signal transduction; Protein kinase C; Biochemistry; Apoptosis","score_opus":0.005715173268399151,"score_gpt":0.23604590975143705,"score_spread":0.2303307364830379,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972995615","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99692595,0.0003451852,0.0004618327,0.00017840895,0.00079626485,0.000549,0.00006680218,0.00006621383,0.0006103595],"genre_scores_gemma":[0.99736154,0.000013595912,0.00066908606,0.000504521,0.00034156066,0.000013194576,0.00008858584,0.00003389351,0.00097403233],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888504,0.000032244643,0.0003665025,0.0002840313,0.00016402372,0.0002681759],"domain_scores_gemma":[0.999069,0.00005794787,0.00014219584,0.00039187353,0.00017402956,0.00016499219],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019444295,0.00017801517,0.00036448485,0.00012259881,0.00006660767,0.000026299183,0.0001269668,0.0001580479,0.000787843],"category_scores_gemma":[0.000048931182,0.00016134878,0.00013685548,0.00015438817,0.0000639583,0.00006386619,0.000052734817,0.00018523535,0.00011213986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005712315,0.00028904979,0.001293357,0.0000644051,0.000049936247,0.000018769768,0.00030267058,0.0000037627942,0.9957715,0.0001520186,0.0003509926,0.00113226],"study_design_scores_gemma":[0.0025647236,0.000192936,0.029292317,0.00006952958,0.00007444807,0.000009517413,0.000033725373,0.00001745927,0.95910174,0.00009150477,0.008415103,0.00013697759],"about_ca_topic_score_codex":0.00003430183,"about_ca_topic_score_gemma":0.0000057965904,"teacher_disagreement_score":0.036669787,"about_ca_system_score_codex":0.000030469875,"about_ca_system_score_gemma":0.00013969112,"threshold_uncertainty_score":0.8626328},"labels":[],"label_agreement":null},{"id":"W1973297275","doi":"10.1053/j.gastro.2013.09.006","title":"MIR106B and MIR93 Prevent Removal of Bacteria From Epithelial Cells by Disrupting ATG16L1-Mediated Autophagy","year":2013,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":117,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Research Resources; National Cancer Institute; National Institute of Allergy and Infectious Diseases; Hospital for Sick Children; University of Alabama at Birmingham","keywords":"ATG16L1; Autophagy; Luciferase; Biology; Transfection; microRNA; Cell culture; Ectopic expression; Downregulation and upregulation; Molecular biology; Chemistry; Cell biology; Gene; Apoptosis; Biochemistry","score_opus":0.005398111659488399,"score_gpt":0.2262101990890761,"score_spread":0.22081208742958772,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973297275","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978802,0.00041977156,0.0001825927,0.0004923406,0.00027081667,0.00040925562,0.00023534117,0.00004833391,0.00006133057],"genre_scores_gemma":[0.99650836,0.00012193383,0.001463721,0.0011769282,0.00015410628,0.000036342582,0.00022961944,0.000029535662,0.00027943874],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985722,0.00012869226,0.0004206732,0.00033951516,0.00014219373,0.00039677732],"domain_scores_gemma":[0.9991631,0.000071958246,0.00019069918,0.0002914023,0.00005456025,0.00022827926],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000085732645,0.00020602533,0.00047977304,0.00006282421,0.000034742698,0.000010970124,0.00010994355,0.00012947041,0.0014523388],"category_scores_gemma":[0.000025357716,0.00017791058,0.00010098893,0.000042928037,0.00017928844,0.00007729284,0.00007711735,0.0001579759,0.00008223846],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007564343,0.00034237542,0.018713035,0.00003567888,0.00023646782,0.00008680322,0.00026726755,3.8161417e-7,0.97573996,0.0000051110064,0.0018511496,0.0019653412],"study_design_scores_gemma":[0.0106301615,0.0030292948,0.7181106,0.00013195476,0.00034271312,0.00037512108,0.00019400945,0.00087118096,0.26040992,0.00048577337,0.0051492723,0.00026999364],"about_ca_topic_score_codex":0.00027971796,"about_ca_topic_score_gemma":0.000008282032,"teacher_disagreement_score":0.71533,"about_ca_system_score_codex":0.000023763243,"about_ca_system_score_gemma":0.000023601342,"threshold_uncertainty_score":0.99946046},"labels":[],"label_agreement":null},{"id":"W1973411587","doi":"10.1042/cs20090310","title":"Dining in with BCL-2: new guests at the autophagy table","year":2009,"lang":"en","type":"review","venue":"Clinical Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Autophagy; Neurodegeneration; Cell biology; Ubiquitin; Biology; Apoptosis; Programmed cell death; ULK1; Organelle; Catabolism; Neuroscience; Metabolism; Biochemistry; Disease; Gene; Medicine; Internal medicine; Protein kinase A","score_opus":0.1441268860545223,"score_gpt":0.49576425191455975,"score_spread":0.35163736586003747,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973411587","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007576961,0.99270743,0.000012393963,0.00029849156,0.00031262668,0.00071262824,0.0000028657994,0.000048771723,0.0051470706],"genre_scores_gemma":[0.0002718842,0.9887202,0.00020192636,0.001187235,0.0005160917,0.000020895084,0.00000946918,0.000020920708,0.009051387],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99709725,0.00013006652,0.00084611314,0.000775208,0.0006153954,0.0005359389],"domain_scores_gemma":[0.9975716,0.0006622779,0.00033494097,0.0008833645,0.000049464976,0.0004983572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0020282187,0.00028831026,0.001381603,0.00010360735,0.00018955558,0.00005505869,0.0007634544,0.00021355355,0.00030693854],"category_scores_gemma":[0.0006980852,0.00013537638,0.00027629544,0.0015867782,0.0010436231,0.000116948926,0.00016737192,0.00070734,0.00031494268],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002666973,0.00011378665,0.00018804558,0.0002268654,0.0000185495,0.00014008555,0.000019325233,0.0000010448373,3.6424058e-7,0.000120461395,0.0016152356,0.99752957],"study_design_scores_gemma":[0.0006362494,0.00038571944,0.0030484125,0.0074845757,0.00024291607,0.00008706489,0.0000043018813,0.000020545409,0.0000026224618,0.000120342535,0.9877763,0.00019096637],"about_ca_topic_score_codex":0.000037410427,"about_ca_topic_score_gemma":0.000020703475,"teacher_disagreement_score":0.9973386,"about_ca_system_score_codex":0.0002018252,"about_ca_system_score_gemma":0.0033440613,"threshold_uncertainty_score":0.59322214},"labels":[],"label_agreement":null},{"id":"W1973638222","doi":"10.1073/pnas.1000063107","title":"Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy","year":2010,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":279,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Autophagy; Rab; Cell biology; Guanine nucleotide exchange factor; Autophagosome; GTPase; Biology; Lysosome; Vacuole; Vesicle; Chemistry; Cytoplasm; Biochemistry; Membrane","score_opus":0.03069313925684326,"score_gpt":0.33379812236289275,"score_spread":0.3031049831060495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973638222","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9621959,0.00011630395,7.62531e-7,0.029490339,0.00006594812,0.0006556322,0.0000141534165,0.000024949739,0.0074360343],"genre_scores_gemma":[0.9934435,0.000011130124,0.0014293202,0.0039481507,0.0002897169,0.000050021164,1.2226742e-7,0.000007485391,0.00082054734],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997886,0.0000044473773,0.00028473893,0.000290372,0.0013149569,0.0002194561],"domain_scores_gemma":[0.9992908,0.00006631416,0.00018534428,0.000022205013,0.00029304333,0.00014228791],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011633292,0.00012441422,0.00020026456,0.00017141925,0.00024132019,0.0000257661,0.0008671582,0.00008641705,0.0000809586],"category_scores_gemma":[0.0006792316,0.00006475069,0.00011957704,0.0011464569,0.00043307713,0.00017282215,0.00011083562,0.00027730167,0.000012629014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000901346,0.00013420463,0.0009716991,0.000041512227,0.000037353548,4.792439e-8,0.0011344,0.000010678232,0.9720734,0.015439223,0.0047808196,0.0052865692],"study_design_scores_gemma":[0.00033881757,0.0001744751,0.15614097,0.000098156495,0.00003178372,0.000021680837,0.00011297199,0.00028412038,0.8197001,0.012122409,0.010880552,0.000093915514],"about_ca_topic_score_codex":0.000005631332,"about_ca_topic_score_gemma":2.073852e-7,"teacher_disagreement_score":0.15516928,"about_ca_system_score_codex":0.000020900867,"about_ca_system_score_gemma":0.0000902141,"threshold_uncertainty_score":0.26404566},"labels":[],"label_agreement":null},{"id":"W1973836920","doi":"10.1073/pnas.1313618111","title":"BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy","year":2014,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Windsor; Canadian Nautical Research Society","funders":"","keywords":"Biology; Autophagy; Acetylation; Cytosol; Cell biology; BAG3; Intracellular; Regulator; Biochemistry; Enzyme; Gene; Apoptosis","score_opus":0.016948217709037275,"score_gpt":0.28060177732668584,"score_spread":0.2636535596176486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973836920","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957976,0.00037487975,0.000001584621,0.0012642955,0.000015564976,0.00038454818,0.000005830961,0.000024511652,0.0021311867],"genre_scores_gemma":[0.9987987,0.00003316664,0.00056822656,0.00007623801,0.000053240732,0.000012911994,2.75201e-7,0.000007301157,0.00044988858],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980958,0.000010786483,0.00044675943,0.0002570646,0.0010373158,0.00015227501],"domain_scores_gemma":[0.9990839,0.000058517413,0.00052898854,0.000015861506,0.0002525957,0.000060187725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009688547,0.00011931753,0.00025631575,0.00020602994,0.00014887343,0.000012100325,0.0002917267,0.00012100959,0.00003908815],"category_scores_gemma":[0.0003871743,0.000081371036,0.000083240564,0.00047174765,0.0006398852,0.00033327148,0.00009424821,0.00015883625,0.00000122807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006401276,0.000084979474,0.0051196823,0.00024653334,0.000048629634,1.7430455e-8,0.0002682437,0.00010172698,0.9651146,0.028152011,0.000012982386,0.00078655855],"study_design_scores_gemma":[0.00060860516,0.00008297977,0.3052304,0.00020053246,0.00002473318,0.000010094,0.000040052797,0.0041055395,0.6608625,0.02877081,0.0000085171,0.00005520992],"about_ca_topic_score_codex":0.0000060430093,"about_ca_topic_score_gemma":2.0521705e-8,"teacher_disagreement_score":0.3042521,"about_ca_system_score_codex":0.000029896082,"about_ca_system_score_gemma":0.00003814981,"threshold_uncertainty_score":0.33182144},"labels":[],"label_agreement":null},{"id":"W1974167705","doi":"10.1155/2012/382175","title":"The Emerging Role of Proteolysis in Mitochondrial Quality Control and the Etiology of Parkinson’s Disease","year":2012,"lang":"en","type":"article","venue":"Parkinson s Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Mitophagy; Disease; Mitochondrion; Biology; Neuroscience; Parkinson's disease; Bioinformatics; Medicine; Cell biology; Autophagy; Apoptosis; Genetics; Pathology","score_opus":0.010735652786394333,"score_gpt":0.29018896312079046,"score_spread":0.27945331033439613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974167705","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96720034,0.029014802,0.000063872125,0.001956445,0.00017532744,0.0013053311,0.0000935899,0.000019503499,0.00017081229],"genre_scores_gemma":[0.99784833,0.00094387884,0.000031761225,0.000391065,0.00028120805,0.00042181613,0.000014801343,0.000019492662,0.00004765571],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99765635,0.00074690423,0.00060419634,0.0002483416,0.00035881292,0.00038539214],"domain_scores_gemma":[0.99785197,0.0006502421,0.00032382912,0.00061057403,0.0000842191,0.00047916337],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000879701,0.00019410119,0.0005170871,0.000077636636,0.00012268519,0.0000104896735,0.00017400648,0.000058351518,0.00006700946],"category_scores_gemma":[0.00086218846,0.00011047147,0.00027245877,0.0001867219,0.0006556337,0.00008744781,0.000052971096,0.00016242787,0.0000047843987],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.033164825,0.0007929347,0.94727206,0.0001874751,0.00030048584,0.0000097360435,0.001126506,0.00001288399,0.0022593916,0.0065968563,0.00012359058,0.008153255],"study_design_scores_gemma":[0.008700248,0.00004089424,0.9684847,0.00006897003,0.00046991845,9.3702937e-7,0.00039588,0.00063252886,0.0004755335,0.002738162,0.017865472,0.00012673227],"about_ca_topic_score_codex":0.00015302337,"about_ca_topic_score_gemma":0.000013260515,"teacher_disagreement_score":0.030648002,"about_ca_system_score_codex":0.000028601375,"about_ca_system_score_gemma":0.00016027754,"threshold_uncertainty_score":0.45048958},"labels":[],"label_agreement":null},{"id":"W1974379210","doi":"10.1074/jbc.m109806200","title":"Parkin and CASK/LIN-2 Associate via a PDZ-mediated Interaction and Are Co-localized in Lipid Rafts and Postsynaptic Densities in Brain","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":189,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; University of California, San Francisco; Parkinson's Foundation","keywords":"Parkin; PDZ domain; CASK; Ubiquitin ligase; Cell biology; Ubiquitin; Postsynaptic density; Postsynaptic potential; Scaffold protein; Biology; Biochemistry; Parkinson's disease; Genetics; Receptor; Signal transduction","score_opus":0.02343620764784024,"score_gpt":0.2781195869868734,"score_spread":0.2546833793390332,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974379210","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99463576,0.0038522054,0.000002903981,0.0013304059,0.000025103764,0.00006483096,0.0000055010055,0.000007549134,0.0000757679],"genre_scores_gemma":[0.99721175,0.0018555863,0.000027102613,0.00073882146,0.00010315837,0.000002030205,0.000005806124,0.0000055062637,0.000050209575],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99918437,0.0000727375,0.00035718107,0.00013747558,0.000096335534,0.00015191514],"domain_scores_gemma":[0.9992292,0.00031490327,0.00022465209,0.000049738992,0.00004010949,0.00014139099],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027169613,0.00012151499,0.0004056962,0.00005146693,0.00002173458,0.000015607198,0.000030474996,0.00018082983,0.000112177695],"category_scores_gemma":[0.00044254598,0.00008585651,0.000042918527,0.00006935595,0.00011806043,0.000051313615,0.000019991181,0.000378374,0.0000010034915],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020780144,0.00049529015,0.57463217,0.00016728342,0.000191054,0.0023422441,0.00066593185,0.0000016724631,0.41417786,0.0000011165238,0.00041503858,0.0048323222],"study_design_scores_gemma":[0.013521383,0.00087383896,0.93715745,0.00097554695,0.00009829884,0.003834978,0.0018102123,0.004110833,0.035543814,0.0004123969,0.0012701453,0.0003911083],"about_ca_topic_score_codex":0.000008120384,"about_ca_topic_score_gemma":0.0000041018866,"teacher_disagreement_score":0.37863404,"about_ca_system_score_codex":0.00006629857,"about_ca_system_score_gemma":0.000012744671,"threshold_uncertainty_score":0.35011268},"labels":[],"label_agreement":null},{"id":"W1974560134","doi":"10.1038/cdd.2009.49","title":"Superoxide is the major reactive oxygen species regulating autophagy","year":2009,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":792,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Manitoba Health Research Council; CancerCare Manitoba Foundation; U.S. Department of Defense","keywords":"Autophagy; Reactive oxygen species; Programmed cell death; Chemistry; Intracellular; Superoxide; Superoxide dismutase; Biochemistry; Hydrogen peroxide; Mitochondrion; Catalase; Mitochondrial ROS; Cell biology; Apoptosis; Biology; Oxidative stress; Enzyme","score_opus":0.014699577991038795,"score_gpt":0.24311625260145803,"score_spread":0.22841667461041923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974560134","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99003035,0.001043207,0.00037134162,0.0009869748,0.0000606271,0.00023773815,0.0000052225864,0.00004895086,0.007215595],"genre_scores_gemma":[0.993873,0.00012948942,0.0001133711,0.0014609867,0.00018472158,0.0000061177743,0.00006346653,0.000008776831,0.0041600754],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9993368,0.00002618504,0.00014426153,0.00018176869,0.00015425998,0.00015675879],"domain_scores_gemma":[0.9995779,0.00003857152,0.000061010065,0.00019682177,0.000040196137,0.00008551838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000053108524,0.00011910373,0.00014477938,0.000041819054,0.0001754129,0.000038202696,0.00004393562,0.00006022773,0.00020164641],"category_scores_gemma":[0.000015313977,0.000077311146,0.000070204056,0.00006375411,0.00002335386,0.00008095216,0.000011414868,0.00008890297,0.00001249384],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008103472,0.00073985563,0.043003842,0.00013462204,0.0002589814,0.00003519341,0.0069548,0.0000021838086,0.8984813,0.013512571,0.0033783417,0.03268793],"study_design_scores_gemma":[0.00093574944,0.0001119844,0.81196725,0.000022528233,0.00012256236,0.000006157215,0.0001491603,0.0006084993,0.1817037,0.003794586,0.00049742823,0.00008037872],"about_ca_topic_score_codex":0.000009457657,"about_ca_topic_score_gemma":6.7391824e-7,"teacher_disagreement_score":0.7689634,"about_ca_system_score_codex":0.000026048963,"about_ca_system_score_gemma":0.000020805439,"threshold_uncertainty_score":0.31526572},"labels":[],"label_agreement":null},{"id":"W1974760106","doi":"10.1158/1538-7445.am2013-1674","title":"Abstract 1674: Inhibition of GSK3 reduces p70S6K activity and promotes autophagy independently of the JNK-cJun pathway.","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Autophagy; Programmed cell death; Apoptosis; Cancer research; Pancreatic cancer; Cell culture; GSK-3; Small hairpin RNA; Cancer cell; Growth inhibition; Cell biology; Chemistry; Cell growth; Signal transduction; Biology; Cancer; Medicine; Internal medicine; Biochemistry; Gene knockdown","score_opus":0.05522335914205901,"score_gpt":0.3775434836466359,"score_spread":0.3223201245045769,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974760106","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948375,0.0015272617,0.0000010950853,0.001063885,0.00006348612,0.00083430106,0.000029565033,0.00001440252,0.0016285093],"genre_scores_gemma":[0.9986584,0.00037850076,0.000010871102,0.000036801604,0.00010410251,0.00012953934,0.0000028759641,0.00001672002,0.00066214835],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985432,0.00010871085,0.00019844896,0.00022283451,0.0006661693,0.00026064357],"domain_scores_gemma":[0.9989865,0.00010783248,0.00010807309,0.0003265054,0.00035217323,0.00011893795],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00043798488,0.000099473036,0.000226187,0.00011456827,0.00009424144,0.000017994145,0.00012191597,0.00010306502,0.0011117965],"category_scores_gemma":[0.000113128495,0.00006557541,0.000071019276,0.00024666634,0.00043300007,0.00015885498,0.0000967242,0.00038615233,0.00001067441],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015918,0.00022479682,0.0023223863,0.0002859463,0.0000624766,0.000006375452,0.00047170793,7.9952326e-7,0.9609623,0.00013856884,0.00040797616,0.034957502],"study_design_scores_gemma":[0.0005235734,0.0001165086,0.3323699,0.0002236028,0.000008410099,0.000002585831,0.00009559581,0.000013304791,0.66551155,0.0010336434,0.00006229173,0.000039065133],"about_ca_topic_score_codex":0.001470643,"about_ca_topic_score_gemma":0.000029792354,"teacher_disagreement_score":0.33004752,"about_ca_system_score_codex":0.00007116749,"about_ca_system_score_gemma":0.00047340736,"threshold_uncertainty_score":0.99980134},"labels":[],"label_agreement":null},{"id":"W1974844459","doi":"10.1371/journal.ppat.1002691","title":"Nitazoxanide Stimulates Autophagy and Inhibits mTORC1 Signaling and Intracellular Proliferation of Mycobacterium tuberculosis","year":2012,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":148,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; British Columbia Centre for Disease Control; University of British Columbia","keywords":"Nitazoxanide; Autophagy; Mycobacterium tuberculosis; mTORC1; Biology; Phagosome; Lysosome; Tuberculosis; Microbiology; Cell biology; Signal transduction; PI3K/AKT/mTOR pathway; Intracellular; Immunology; Medicine; Apoptosis; Biochemistry","score_opus":0.015684860658716427,"score_gpt":0.2435039758849041,"score_spread":0.22781911522618767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974844459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942884,0.0049612788,0.00008781117,0.00007496921,0.00004998301,0.00037955266,0.000030705418,0.000052576943,0.000074760705],"genre_scores_gemma":[0.9985252,0.00021853486,0.00070991577,0.0001566425,0.00026383816,0.00002043953,0.000038528116,0.000028937297,0.000037953294],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906105,0.000052669373,0.00026674452,0.00018865292,0.00018344926,0.0002474438],"domain_scores_gemma":[0.99936825,0.00006528423,0.00008499426,0.00016314,0.00009008982,0.0002282284],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016209239,0.00016310927,0.00030023765,0.000085956824,0.00006663923,0.000014926616,0.000025004087,0.00010589466,0.00009289588],"category_scores_gemma":[0.00007512495,0.00014078451,0.00004852158,0.000092429276,0.000067364526,0.0001732119,0.000032425003,0.00010035504,0.000007955843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009133235,0.00026157373,0.09933759,0.00025177485,0.0001412807,0.000011519122,0.00118111,0.0000045443976,0.8974272,0.00014599682,0.000006908928,0.0011391768],"study_design_scores_gemma":[0.00084648706,0.00021609625,0.08512698,0.00014368996,0.00039194312,0.00003943693,0.00013024012,0.0011034244,0.9116727,0.00013296283,0.000044577628,0.00015143653],"about_ca_topic_score_codex":0.000004693564,"about_ca_topic_score_gemma":3.806924e-7,"teacher_disagreement_score":0.014245533,"about_ca_system_score_codex":0.00002028177,"about_ca_system_score_gemma":0.00003031501,"threshold_uncertainty_score":0.5741026},"labels":[],"label_agreement":null},{"id":"W1975826911","doi":"10.1158/1538-7445.am2012-2468","title":"Abstract 2468: Inhibition of autophagy as a potential mechanism by which pantoprazole, a proton pump inhibitor (PPI), enhances the therapeutic effect of docetaxel chemotherapy for solid tumors","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Social Innovation; University of Toronto","funders":"","keywords":"Autophagy; Docetaxel; Cytotoxicity; Pharmacology; Lysosome; Programmed cell death; In vivo; Chemistry; Autophagosome; Apoptosis; Cell biology; In vitro; Cancer research; Biology; Cancer; Biochemistry; Medicine; Internal medicine; Enzyme","score_opus":0.027123534589916762,"score_gpt":0.39297428496530257,"score_spread":0.3658507503753858,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975826911","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98815167,0.005297131,0.00015950696,0.00089325116,0.00019836318,0.004955271,0.00008323032,0.000037443537,0.00022415073],"genre_scores_gemma":[0.9946352,0.0011905236,0.000017151,0.00020508748,0.00063281565,0.002913854,0.00003630383,0.00006518573,0.00030383992],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99711525,0.00024233363,0.00049991405,0.00033906236,0.0010434343,0.0007599975],"domain_scores_gemma":[0.9982492,0.00030888905,0.00025809565,0.00045973965,0.000513458,0.00021065994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021656777,0.00026143657,0.00058162666,0.00017794916,0.00019388266,0.0000272057,0.00023894705,0.00018453554,0.0006412317],"category_scores_gemma":[0.00011149484,0.00016715229,0.00023651832,0.00047838868,0.0003016124,0.00020313614,0.0000463704,0.00045273482,0.000016954322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004132425,0.0004967184,0.00016301817,0.0011590042,0.00031089163,0.0000034225334,0.0007967537,0.0000022573565,0.9840604,0.0003327653,0.00043508745,0.0081072245],"study_design_scores_gemma":[0.0040612994,0.0018247957,0.002129548,0.00043572907,0.00008982357,0.000010326571,0.00018072163,0.00007233807,0.9890454,0.0012382535,0.0007648483,0.00014691033],"about_ca_topic_score_codex":0.0002469498,"about_ca_topic_score_gemma":0.000005477013,"teacher_disagreement_score":0.007960314,"about_ca_system_score_codex":0.00013180386,"about_ca_system_score_gemma":0.00046987605,"threshold_uncertainty_score":0.70210373},"labels":[],"label_agreement":null},{"id":"W1975853352","doi":"10.1038/nm.3371","title":"Mst-1 switches between cardiac cell life and death","year":2013,"lang":"en","type":"letter","venue":"Nature Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Autophagy; Programmed cell death; Apoptosis; Cell biology; Cell fate determination; Biology; Disease; Cell; Cardiac cell; Cell survival; Cancer research; Medicine; Genetics; Internal medicine; Transcription factor; Gene","score_opus":0.014534149039970747,"score_gpt":0.2753224190576323,"score_spread":0.2607882700176615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975853352","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07136455,0.125705,0.00001343167,0.7864525,0.0015092795,0.0011757597,0.00010379893,0.00020625618,0.01346943],"genre_scores_gemma":[0.10648514,0.0030554885,0.00011218339,0.8269582,0.04599674,0.000061756866,0.0017154644,0.00015775525,0.01545731],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972469,0.00007895845,0.0004645522,0.00070491986,0.0009501631,0.0005544606],"domain_scores_gemma":[0.99791795,0.0003571129,0.0002322026,0.0008012732,0.00019748916,0.0004939635],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00024125206,0.0006471951,0.0016443429,0.0003080971,0.00008847652,0.000018416244,0.00022812508,0.003139733,0.0009267112],"category_scores_gemma":[0.00021950573,0.0004285887,0.00022442278,0.00019649121,0.00019690995,0.000058803584,0.00006772682,0.006120966,0.0001405334],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030991814,0.00001882048,0.009255619,0.0007331825,0.0005068065,0.00035719597,0.00013862093,9.111088e-9,0.0003398804,0.000011547921,0.9868374,0.0017699468],"study_design_scores_gemma":[0.0021051818,0.00042169626,0.031383347,0.0005956766,0.0015758917,0.000020708425,0.000040505147,0.0000014298333,0.0009310918,0.0003530281,0.9621824,0.00038904572],"about_ca_topic_score_codex":0.00008008381,"about_ca_topic_score_gemma":2.4285228e-7,"teacher_disagreement_score":0.12264952,"about_ca_system_score_codex":0.00007200992,"about_ca_system_score_gemma":0.00023120616,"threshold_uncertainty_score":0.9999866},"labels":[],"label_agreement":null},{"id":"W1975948071","doi":"10.1016/j.expneurol.2013.09.017","title":"Increased autophagy in peripheral nerves may protect Wistar Ottawa Karlsburg W rats against neuropathy","year":2013,"lang":"en","type":"article","venue":"Experimental Neurology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Universität Greifswald; Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"Autophagy; Sciatic nerve; ATG5; Endocrinology; Peripheral neuropathy; Internal medicine; Inflammation; Medicine; Biology; Pathology; Apoptosis; Diabetes mellitus","score_opus":0.010104564047380443,"score_gpt":0.2632987704538671,"score_spread":0.2531942064064867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975948071","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921202,0.0015198635,0.0000050134922,0.0011740035,0.0003933102,0.0014120913,0.0000054487955,0.00020140159,0.0031686374],"genre_scores_gemma":[0.98444754,0.000024747333,0.00011074638,0.014099667,0.00026457667,0.0005573577,0.000038468123,0.00007771665,0.0003791913],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976886,0.00036586632,0.0004685047,0.0006278642,0.0002469621,0.00060219667],"domain_scores_gemma":[0.9989974,0.00005277972,0.00010881055,0.00049789937,0.000035505203,0.00030758878],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00010468356,0.00036614705,0.0005053577,0.00018292003,0.000094922485,0.00003503042,0.0002124202,0.00018409443,0.0018678232],"category_scores_gemma":[0.00004036865,0.00033250256,0.00016809248,0.0002157613,0.00024595726,0.00020298784,0.000095892276,0.00045579448,0.00026328606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00097091525,0.0012258112,0.014708327,0.000026451373,0.00004494468,0.0021316567,0.0005774161,0.000019445311,0.9771468,0.00019011376,0.001662306,0.0012958201],"study_design_scores_gemma":[0.007229797,0.0039418824,0.3145728,0.000030297357,0.000015973248,0.00034045114,0.0001785439,0.0018851168,0.66349256,0.00015238013,0.0076262597,0.00053392735],"about_ca_topic_score_codex":0.00046909123,"about_ca_topic_score_gemma":0.000007287387,"teacher_disagreement_score":0.31365424,"about_ca_system_score_codex":0.00006052937,"about_ca_system_score_gemma":0.000099581586,"threshold_uncertainty_score":0.9999127},"labels":[],"label_agreement":null},{"id":"W1976291093","doi":"10.1016/j.cellsig.2014.01.012","title":"Induction of autophagy biomarker BNIP3 requires a JAK2/STAT3 and MT1-MMP signaling interplay in Concanavalin-A-activated U87 glioblastoma cells","year":2014,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Autophagy; Cell biology; Gene silencing; Biology; Signal transduction; Phosphorylation; STAT3; Protein kinase B; Cancer research; Gene; Biochemistry; Apoptosis","score_opus":0.01485667993932395,"score_gpt":0.26718272270169335,"score_spread":0.2523260427623694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976291093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99004215,0.0014163478,0.0075238356,0.00005742293,0.00023829889,0.00038483692,0.0000070871706,0.000081918195,0.00024807718],"genre_scores_gemma":[0.9988186,0.0000731179,0.00057010213,0.00016088855,0.00015344837,0.000016829692,0.000028451932,0.00005852847,0.00012004929],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99794185,0.00021071322,0.0006655965,0.00047698038,0.00031803502,0.000386796],"domain_scores_gemma":[0.9988767,0.00022103151,0.00028303132,0.0002856447,0.00012331846,0.00021031279],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006274565,0.0002971106,0.00058983295,0.00039633803,0.0000768296,0.000030348096,0.00012385739,0.00022096526,0.00026152306],"category_scores_gemma":[0.000083018494,0.00028166157,0.00013877534,0.00041085004,0.00017732309,0.00016138276,0.000048235284,0.0003000551,0.000011786245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00078385684,0.00016591632,0.0004742381,0.00020390688,0.00016187395,0.00010690687,0.0008702397,0.00019608438,0.99158347,0.0001435363,0.00002781904,0.0052821734],"study_design_scores_gemma":[0.0023685298,0.0005087291,0.0006423223,0.00062702654,0.00011478778,0.000019286363,0.00028155313,0.013353909,0.9809396,0.0004554329,0.0004301694,0.00025861317],"about_ca_topic_score_codex":0.00012808065,"about_ca_topic_score_gemma":0.000008281182,"teacher_disagreement_score":0.013157825,"about_ca_system_score_codex":0.000084356245,"about_ca_system_score_gemma":0.000107225125,"threshold_uncertainty_score":0.9999636},"labels":[],"label_agreement":null},{"id":"W1976531450","doi":"10.1038/sj.cdd.4401984","title":"ER stress (PERK/eIF2α phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation","year":2006,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":925,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Japan Society for the Promotion of Science; National Institutes of Health; School of Medicine, New York University; York University","keywords":"Autophagy; Unfolded protein response; ATG5; Cell biology; Endoplasmic reticulum; Programmed cell death; ATG12; Phosphorylation; Chemistry; Biology; Apoptosis; Biochemistry","score_opus":0.00979801043986246,"score_gpt":0.24013825156330898,"score_spread":0.23034024112344653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976531450","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98531777,0.0006776307,0.01247715,0.00016716412,0.0002735263,0.0007123276,0.000043494027,0.000073333955,0.00025761916],"genre_scores_gemma":[0.99687606,0.00008780941,0.00014337551,0.00018557906,0.00041918908,0.000064007014,0.0017590688,0.000021246611,0.0004436391],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990204,0.000042862535,0.00027344364,0.00022645123,0.00022226977,0.00021459036],"domain_scores_gemma":[0.9993304,0.00007444607,0.00015313542,0.0002062153,0.00012625488,0.000109576344],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008702683,0.0001731905,0.0001813965,0.0000772098,0.0002755958,0.00006947054,0.00006655251,0.000117661875,0.00012603839],"category_scores_gemma":[0.000013880662,0.00012279922,0.00008528282,0.00007578097,0.000029154988,0.00029757086,0.000015654214,0.00007808215,0.000009793225],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004844517,0.00505203,0.18365726,0.0022693458,0.0005292089,0.000034161825,0.005284169,0.00016755325,0.7131896,0.023179026,0.005220375,0.05657277],"study_design_scores_gemma":[0.0042138444,0.00027372758,0.49731326,0.000029066088,0.00032026798,0.000004767376,0.00026893095,0.050287418,0.44566688,0.0010962962,0.00032831653,0.00019723442],"about_ca_topic_score_codex":0.0000818686,"about_ca_topic_score_gemma":0.00002027284,"teacher_disagreement_score":0.313656,"about_ca_system_score_codex":0.000029742645,"about_ca_system_score_gemma":0.000040788782,"threshold_uncertainty_score":0.5007607},"labels":[],"label_agreement":null},{"id":"W1976589077","doi":"10.1038/cdd.2014.58","title":"Dominant-negative function of the C-terminal fragments of NBR1 and SQSTM1 generated during enteroviral infection","year":2014,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital","funders":"Canadian Institutes of Health Research; University of British Columbia; China Scholarship Council","keywords":"Biology; Autophagy; Signal transducing adaptor protein; Coxsackievirus; Ubiquitin; Deubiquitinating enzyme; Virus; Cell biology; Virology; Signal transduction; Gene; Enterovirus; Genetics; Apoptosis","score_opus":0.006893420154357874,"score_gpt":0.21709340410835118,"score_spread":0.2101999839539933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976589077","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99797076,0.00009968916,0.0014532374,0.000007962793,0.00012549876,0.00016717624,0.0000029264806,0.0000064180645,0.00016630575],"genre_scores_gemma":[0.999621,0.00010205192,0.000019026671,0.0000288548,0.00004309071,0.000005693872,0.000015589472,0.000005418603,0.00015931857],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99954075,0.000046698256,0.00014649231,0.00010474927,0.000095007585,0.000066326036],"domain_scores_gemma":[0.9996809,0.000020294636,0.00013215996,0.00008650644,0.000043580967,0.00003657351],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004061188,0.00007425808,0.0001289399,0.000047137128,0.00006215611,0.000006214736,0.000014239881,0.000046243935,0.000021949749],"category_scores_gemma":[0.000017279062,0.000050536662,0.000038093156,0.000044740245,0.000033437456,0.000054611228,0.000016831382,0.00004558931,5.049102e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052292016,0.00015182824,0.65872127,0.0002509435,0.000043510594,4.4666297e-7,0.00027152343,0.0000031640839,0.3377969,0.00007672441,0.000006302757,0.0021544688],"study_design_scores_gemma":[0.0017231364,0.00014250884,0.7050553,0.000045597328,0.000109556175,0.0000019341105,0.000010675835,0.00086180284,0.29180202,0.00021399716,0.0000038547587,0.000029637318],"about_ca_topic_score_codex":0.000028387678,"about_ca_topic_score_gemma":0.0000027477304,"teacher_disagreement_score":0.046334013,"about_ca_system_score_codex":0.000010338051,"about_ca_system_score_gemma":0.00000838052,"threshold_uncertainty_score":0.20608252},"labels":[],"label_agreement":null},{"id":"W1977058383","doi":"10.1371/journal.pone.0119382","title":"Autophagic Signaling and Proteolytic Enzyme Activity in Cardiac and Skeletal Muscle of Spontaneously Hypertensive Rats following Chronic Aerobic Exercise","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Internal medicine; Endocrinology; Autophagy; Skeletal muscle; Medicine; Calpain; Cathepsin; Aerobic exercise; Protein kinase B; Muscle atrophy; Chemistry; Signal transduction; Biology; Apoptosis; Cell biology; Enzyme; Biochemistry","score_opus":0.032754466238813035,"score_gpt":0.24280023806514167,"score_spread":0.21004577182632864,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977058383","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876668,0.011069473,0.00000459257,0.00010895515,0.00003510968,0.0009818248,0.000004429242,0.00003991226,0.0000889397],"genre_scores_gemma":[0.99919105,0.00024641576,0.00020929013,0.00005840729,0.00008182401,0.00005337066,0.000005281794,0.000028216433,0.00012617765],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889994,0.00006617483,0.00019608616,0.00028346517,0.00030754282,0.00024680828],"domain_scores_gemma":[0.999355,0.00007146708,0.00007420157,0.0002153383,0.000073668816,0.000210311],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022617313,0.00017065594,0.00068780495,0.00010833042,0.000034611203,0.000011207029,0.000044580553,0.00009321298,0.000012583753],"category_scores_gemma":[0.00008381841,0.0001587884,0.00008002681,0.00013995774,0.0000787637,0.000120446115,0.000042798336,0.00017774913,0.0000051041125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030433142,0.00082616194,0.0018664158,0.00045587853,0.00035698412,0.00090928614,0.0013566354,0.000007053813,0.9897108,0.000012631537,0.0000062490517,0.0041875388],"study_design_scores_gemma":[0.005618748,0.0011317523,0.029399265,0.002411641,0.0010480151,0.000039699964,0.00046468817,0.0031779432,0.95598763,0.00032220787,0.0000139479525,0.00038445415],"about_ca_topic_score_codex":0.00009841762,"about_ca_topic_score_gemma":0.000007173916,"teacher_disagreement_score":0.033723194,"about_ca_system_score_codex":0.00010556172,"about_ca_system_score_gemma":0.0002089793,"threshold_uncertainty_score":0.6475203},"labels":[],"label_agreement":null},{"id":"W1977109589","doi":"10.1101/pdb.prot080325","title":"LysoTracker Staining to Aid in Monitoring Autophagy in <i>Drosophila</i>","year":2014,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; Staining; Biology; Flow cytometry; Cell; Molecular biology; Genetics; Apoptosis","score_opus":0.024109302332924406,"score_gpt":0.32150347008658064,"score_spread":0.29739416775365624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977109589","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9524881,0.000075884964,0.00020299367,0.00030734658,0.0001023239,0.0457915,0.0000015637786,0.00016767444,0.0008625687],"genre_scores_gemma":[0.91567314,0.000003323368,0.0017422498,0.0006009345,0.00039224708,0.0814316,2.9484136e-7,0.00005903955,0.00009717552],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9980752,0.00007979628,0.00047990528,0.00046860744,0.0003310474,0.00056542904],"domain_scores_gemma":[0.99894166,0.00007592321,0.00008126566,0.0005629328,0.00005547851,0.00028273204],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006375789,0.00024155452,0.0004568394,0.00030804385,0.000054026845,0.000050686114,0.00021270406,0.00012629955,0.000040876577],"category_scores_gemma":[0.00021318698,0.00024937917,0.000083134655,0.0004874734,0.0000294642,0.00014214907,0.00008385278,0.0003661087,0.00010186729],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012052822,0.00091163046,0.63738954,0.00059563236,0.000050648687,0.0005485562,0.0006235363,0.0005433616,0.3416292,0.012601602,0.00006034359,0.0038406416],"study_design_scores_gemma":[0.005312029,0.0004288041,0.7104867,0.001990521,0.000011396424,0.0000013056742,0.000020549913,0.00058812124,0.2583345,0.00017001938,0.022304393,0.0003516494],"about_ca_topic_score_codex":0.000048032125,"about_ca_topic_score_gemma":0.0000048432166,"teacher_disagreement_score":0.083294734,"about_ca_system_score_codex":0.00023341573,"about_ca_system_score_gemma":0.0001319758,"threshold_uncertainty_score":0.9999958},"labels":[],"label_agreement":null},{"id":"W1978397479","doi":"10.4161/auto.7.11.17661","title":"A comprehensive glossary of autophagy-related molecules and processes (2<sup>nd</sup>edition)","year":2011,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":291,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Cancer Institute","keywords":"Autophagy; Glossary; Biology; Terminology; Cell biology; Vocabulary; Function (biology); Computational biology; Mechanism (biology); Biochemistry; Linguistics; Physics","score_opus":0.02318933588912548,"score_gpt":0.25550925522819923,"score_spread":0.23231991933907375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978397479","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98039424,0.010890958,0.00021220313,0.00010778854,0.00011102443,0.00052615325,0.0000538782,0.00025247346,0.007451276],"genre_scores_gemma":[0.995948,0.0005428009,0.0016901986,0.0007969086,0.000092095084,0.000049655304,0.00007711539,0.000052888226,0.0007503236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99829334,0.000064509935,0.0005120442,0.00044222406,0.00032873158,0.00035913562],"domain_scores_gemma":[0.99866664,0.00010855894,0.0001972756,0.00042810323,0.00034301338,0.00025638248],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000080742706,0.0003132598,0.0005711525,0.00019002406,0.00010604877,0.000012819431,0.00015614076,0.00020742886,0.0013167777],"category_scores_gemma":[0.000085158914,0.0002770726,0.00013542728,0.00041177528,0.00041165735,0.00021420109,0.00007190607,0.00021794422,0.00009554908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016258815,0.02773269,0.056380965,0.030585367,0.020905085,0.019987348,0.12363286,0.00039897824,0.2744474,0.14476162,0.025101254,0.25980762],"study_design_scores_gemma":[0.011303243,0.0026006047,0.43533847,0.00094811956,0.0010711617,0.0010809109,0.001395415,0.003110759,0.51090336,0.02474626,0.0064148875,0.0010868134],"about_ca_topic_score_codex":0.00007004045,"about_ca_topic_score_gemma":9.3223167e-7,"teacher_disagreement_score":0.3789575,"about_ca_system_score_codex":0.000028511658,"about_ca_system_score_gemma":0.00027078908,"threshold_uncertainty_score":0.9999682},"labels":[],"label_agreement":null},{"id":"W1978850941","doi":"10.1016/j.tcm.2014.08.002","title":"The interplay between cell death signaling pathways in the heart","year":2014,"lang":"en","type":"review","venue":"Trends in Cardiovascular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Cell fate determination; Programmed cell death; Cell biology; Mitophagy; Autophagy; Biology; Mitochondrion; Apoptosis; Cell; Signal transduction; Embryonic stem cell; Genetics; Transcription factor; Gene","score_opus":0.06131576723615606,"score_gpt":0.3665270228871808,"score_spread":0.30521125565102475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978850941","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00018605147,0.9918921,0.00008471977,0.00031927117,0.00037530076,0.00081619824,0.000013475178,0.000048793117,0.006264081],"genre_scores_gemma":[0.012947935,0.98311645,0.00003202465,0.00044479978,0.002521909,0.00027917462,0.00030519825,0.00010791112,0.00024459243],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9945193,0.0015786545,0.0012833962,0.0007052859,0.0012432782,0.00067006523],"domain_scores_gemma":[0.99595875,0.0013763368,0.00022647185,0.0022085805,0.00004870888,0.0001811457],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0062102457,0.00070373603,0.004449696,0.0006406363,0.00014177673,0.00002744278,0.00078379083,0.0004210608,0.000096175405],"category_scores_gemma":[0.0001730989,0.00032363113,0.0027629826,0.0011921383,0.00025471603,0.000034477634,0.00008784399,0.0015864787,0.000054152857],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018037874,0.000054823384,0.00016940356,0.0025261964,0.001324811,0.00040697184,0.00048292705,0.0000041300887,5.3064423e-7,0.00006292717,0.0012267092,0.99372256],"study_design_scores_gemma":[0.001968075,0.000250939,0.0009265353,0.012681278,0.004926986,0.00018475694,0.00015349004,0.000006560257,0.0000036723657,0.000089888425,0.9785085,0.000299357],"about_ca_topic_score_codex":0.000117830736,"about_ca_topic_score_gemma":0.000009532288,"teacher_disagreement_score":0.99342316,"about_ca_system_score_codex":0.00021582225,"about_ca_system_score_gemma":0.00018497829,"threshold_uncertainty_score":0.99992156},"labels":[],"label_agreement":null},{"id":"W1978859255","doi":"10.1371/journal.pone.0016523","title":"Mevalonate Cascade Regulation of Airway Mesenchymal Cell Autophagy and Apoptosis: A Dual Role for p53","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research Manitoba; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft; Natural Sciences and Engineering Research Council of Canada; Manitoba Health Research Council; Deutsche Krebshilfe; GlaxoSmithKline","keywords":"Autophagy; Cell biology; ATG5; Autophagosome; Programmed cell death; Biology; Apoptosis; Chemistry; Cancer research; Biochemistry","score_opus":0.03920315227293666,"score_gpt":0.24108385939220353,"score_spread":0.20188070711926687,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978859255","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99491394,0.0012689905,0.00006350526,0.0000981348,0.000022841527,0.0005553667,0.000026309885,0.000050055634,0.0030008757],"genre_scores_gemma":[0.9942046,0.0000941968,0.00376686,0.00011902501,0.000105088315,0.00006746702,0.000024565821,0.000024685107,0.001593531],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991659,0.000023788574,0.00021885717,0.00019372674,0.00022377392,0.00017396596],"domain_scores_gemma":[0.99943453,0.00003948959,0.000100340505,0.00020550686,0.00010503092,0.00011511963],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000121353696,0.00011406888,0.00028778546,0.00007565236,0.0000429415,0.0000036394117,0.000042047268,0.000093508796,0.00025921286],"category_scores_gemma":[0.000031847063,0.000101501224,0.00006887453,0.00007128171,0.00006580809,0.00007606018,0.000020060583,0.0000670061,0.000010389802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001177675,0.0028695944,0.0013381476,0.0006203025,0.0005603274,0.0000049163446,0.002884601,8.4673957e-7,0.9876694,0.0010235396,0.00014520493,0.0017054335],"study_design_scores_gemma":[0.0020692782,0.0006321866,0.02702787,0.000116309595,0.00053250324,0.0000029517096,0.00010208968,0.0012205322,0.96630996,0.0018475442,0.000039365135,0.00009940942],"about_ca_topic_score_codex":0.000029280976,"about_ca_topic_score_gemma":0.0000013527097,"teacher_disagreement_score":0.025689723,"about_ca_system_score_codex":0.00001597692,"about_ca_system_score_gemma":0.000047792895,"threshold_uncertainty_score":0.41390997},"labels":[],"label_agreement":null},{"id":"W1979539386","doi":"10.1155/2012/595976","title":"Targeting Metabolism and Autophagy in the Context of Haematologic Malignancies","year":2012,"lang":"en","type":"article","venue":"International Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba; Research Manitoba","funders":"","keywords":"Autophagy; Context (archaeology); Metabolism; Cell metabolism; Programmed cell death; Biology; Cancer research; Cell; Cancer; Cellular metabolism; Cell growth; Cell biology; Bioinformatics; Medicine; Apoptosis; Genetics; Biochemistry","score_opus":0.01670208344980456,"score_gpt":0.3000537445892489,"score_spread":0.2833516611394443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979539386","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9833756,0.014796337,0.00008940669,0.0006615802,0.00045291433,0.000049752114,0.0000042249003,0.0000018431056,0.00056834443],"genre_scores_gemma":[0.99750555,0.000809907,0.00029062733,0.0011256394,0.00024078846,0.0000013993136,0.0000033840108,0.0000030827614,0.000019633082],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932486,0.00008933168,0.00032489627,0.000041969775,0.00011695912,0.00010196491],"domain_scores_gemma":[0.9993634,0.00015487672,0.00026148246,0.000044698594,0.00014053045,0.000034997516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043846792,0.000058183803,0.00021735669,0.00010686484,0.000010021975,0.0000036684633,0.00014261682,0.000050935378,0.00008037444],"category_scores_gemma":[0.00009452626,0.000032513115,0.000065102344,0.000035251258,0.0000957521,0.00006370189,0.000020479702,0.00011498162,0.0000024644671],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009948465,0.0009222028,0.2026273,0.000051813993,0.00041513777,0.0003208629,0.0069736997,0.0000056805493,0.7384414,0.037656706,0.000718057,0.010872288],"study_design_scores_gemma":[0.006186677,0.00057655264,0.40599087,0.00013932376,0.00018500094,0.002278527,0.004962356,0.00008737317,0.5364628,0.006010957,0.036933217,0.0001863321],"about_ca_topic_score_codex":0.000009006378,"about_ca_topic_score_gemma":3.66091e-7,"teacher_disagreement_score":0.20336358,"about_ca_system_score_codex":0.000009986684,"about_ca_system_score_gemma":0.00003407938,"threshold_uncertainty_score":0.13258463},"labels":[],"label_agreement":null},{"id":"W1980516906","doi":"10.1371/journal.pone.0042636","title":"Dysregulation of Autophagy in Murine Fibroblasts Resistant to HSV-1 Infection","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Dalhousie University; Northwestern University","keywords":"Autophagy; Autophagosome; Biology; Cytoplasm; Cell biology; Organelle; Programmed cell death; Herpes simplex virus; Cell culture; Cell; Virus; Virology; Apoptosis; Genetics","score_opus":0.04116704273055574,"score_gpt":0.2713829619956772,"score_spread":0.23021591926512144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980516906","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99789625,0.00026532228,0.000049503895,0.00020816666,0.000033542765,0.00034098342,0.0000041158137,0.000043210213,0.0011589234],"genre_scores_gemma":[0.9981236,0.000028492112,0.00089731446,0.0001320506,0.0001736442,0.000026116535,0.000017045184,0.000015114891,0.00058665336],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99924785,0.000028001228,0.00021605995,0.000103620245,0.00022941403,0.00017505114],"domain_scores_gemma":[0.99954414,0.000024735693,0.000055383385,0.00019842727,0.000054406883,0.00012290121],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012824546,0.00007854352,0.00021219807,0.00016817615,0.000015734353,0.00000251099,0.000025224037,0.000054806944,0.00029941997],"category_scores_gemma":[0.00006884971,0.00007465888,0.000035843135,0.00024924453,0.00001606747,0.00009701277,0.000017383843,0.00006450145,0.00006268655],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010136919,0.00470067,0.15738691,0.00043026166,0.00017973268,0.0000066392276,0.0007033127,0.00002362263,0.8330459,0.00071861554,0.00012401224,0.0016666356],"study_design_scores_gemma":[0.0006340312,0.00023572103,0.6525759,0.000288306,0.00005120008,8.4143454e-7,0.0000055108862,0.000093306364,0.3458872,0.00009515691,0.00008290427,0.000049881823],"about_ca_topic_score_codex":0.00006354738,"about_ca_topic_score_gemma":0.000015957296,"teacher_disagreement_score":0.495189,"about_ca_system_score_codex":0.00006982055,"about_ca_system_score_gemma":0.00002563366,"threshold_uncertainty_score":0.32784387},"labels":[],"label_agreement":null},{"id":"W1980912292","doi":"10.1093/brain/awu278","title":"Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits","year":2014,"lang":"en","type":"article","venue":"Brain","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":114,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Advancing Translational Sciences; University of Alberta; National Institute on Aging; National Institute on Alcohol Abuse and Alcoholism; Università di Bologna","keywords":"Lysosome; Cell biology; Autophagy; Biochemistry; Lipofuscin; Sequestosome 1; Chemistry; Ceramide; Endocytic cycle; Alzheimer's disease; Biology; Internal medicine; Enzyme; Endocytosis; Apoptosis","score_opus":0.018961783637896624,"score_gpt":0.29135973641502216,"score_spread":0.27239795277712553,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980912292","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908217,0.00060727337,0.0045883823,0.0009322655,0.000073214156,0.0012286564,0.000015051407,0.000060861534,0.001672569],"genre_scores_gemma":[0.9958612,0.0000034574457,0.0002410421,0.0021677301,0.000117122065,0.00011846522,0.00003451948,0.000041219675,0.0014152915],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998215,0.0004218887,0.00037535606,0.00032249722,0.00034862658,0.0003166351],"domain_scores_gemma":[0.99882966,0.00046585465,0.00017979812,0.00038830715,0.000060412563,0.000075985015],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009909,0.00021245459,0.00034115958,0.00011077665,0.000077931094,0.000017757804,0.00017298074,0.00013640946,0.00006395079],"category_scores_gemma":[0.000516541,0.00015804986,0.00017634268,0.00027781923,0.00008554638,0.00011076051,0.00003377787,0.0003349031,0.00002065319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0044753766,0.0076218224,0.036408238,0.00087738666,0.0019031337,0.00007531425,0.027835052,0.004978867,0.6921743,0.010505549,0.046016004,0.16712894],"study_design_scores_gemma":[0.027618641,0.0045952983,0.06320961,0.0012901886,0.001273863,0.00031844736,0.0024640334,0.25442976,0.61790013,0.021961652,0.0031370455,0.0018013056],"about_ca_topic_score_codex":0.00006685831,"about_ca_topic_score_gemma":0.0000282475,"teacher_disagreement_score":0.24945089,"about_ca_system_score_codex":0.00004516468,"about_ca_system_score_gemma":0.000098719225,"threshold_uncertainty_score":0.6445086},"labels":[],"label_agreement":null},{"id":"W1981785446","doi":"10.1007/s00262-009-0752-1","title":"Autophagy facilitates major histocompatibility complex class I expression induced by IFN-γ in B16 melanoma cells","year":2009,"lang":"en","type":"article","venue":"Cancer Immunology Immunotherapy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Program for New Century Excellent Talents in University; Chinese Academy of Medical Sciences; Chinese Academy of Sciences; National Natural Science Foundation of China; Academy of Medical Sciences","keywords":"Autophagy; Major histocompatibility complex; MHC class I; Cell biology; Biology; CTL*; Regulator; Antigen; Cytolysis; Antigen processing; Immunology; Melanoma; Cytotoxic T cell; Cancer research; Apoptosis; CD8; Genetics","score_opus":0.02402543236678481,"score_gpt":0.3092619242453719,"score_spread":0.28523649187858713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981785446","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95805436,0.03738639,0.000088174034,0.0016385661,0.00046566955,0.0012129032,0.000085525346,0.00021904091,0.0008493902],"genre_scores_gemma":[0.9924948,0.0018406546,0.0002349907,0.003856667,0.000065526925,0.00026498432,0.00012717127,0.000052015555,0.0010631674],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971852,0.00028512755,0.00079983904,0.00073080935,0.00026637505,0.00073265133],"domain_scores_gemma":[0.99835634,0.000114499446,0.00025183085,0.0010402433,0.000112813424,0.00012425016],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00024362234,0.0005003303,0.0009503806,0.00024402887,0.00017141431,0.00002367221,0.00043521027,0.0004355982,0.002598939],"category_scores_gemma":[0.000016275639,0.0004478203,0.00024354395,0.0003517722,0.0002963,0.00018705521,0.000034925928,0.0006357958,0.00008757269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002807946,0.00083511666,0.0014709334,0.000021089796,0.00020757238,0.00002926351,0.0011377103,0.0000042356514,0.940841,0.0000649168,0.002670846,0.049909346],"study_design_scores_gemma":[0.011005618,0.0014221608,0.30629304,0.00014664429,0.000033199085,0.000014840178,0.00018588454,0.000081627586,0.64933985,0.0010569734,0.029922916,0.00049723627],"about_ca_topic_score_codex":0.00046145177,"about_ca_topic_score_gemma":0.000021612288,"teacher_disagreement_score":0.30482212,"about_ca_system_score_codex":0.0006841598,"about_ca_system_score_gemma":0.0002778838,"threshold_uncertainty_score":0.99979734},"labels":[],"label_agreement":null},{"id":"W1983275934","doi":"10.1074/jbc.m110.139915","title":"Inhibition of Autophagosome Formation by the Benzoporphyrin Derivative Verteporfin","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; University of British Columbia","funders":"","keywords":"Verteporfin; Autophagy; In vivo; Cell biology; Chemistry; Autophagosome; Photodynamic therapy; Cytoplasm; Pharmacology; Cancer research; Biology; Biochemistry; Apoptosis","score_opus":0.016494536937977207,"score_gpt":0.2675569011288567,"score_spread":0.2510623641908795,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983275934","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99791414,0.0003400176,0.0001516022,0.0005724117,0.000053517688,0.00005854278,0.000010847803,0.0000073192214,0.00089160225],"genre_scores_gemma":[0.99924225,0.00007668635,0.00014647939,0.00026042806,0.00019219998,0.000001945971,0.000020825919,0.0000035348726,0.000055680262],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930423,0.000016790993,0.00036817967,0.000058866764,0.0001630622,0.00008885734],"domain_scores_gemma":[0.99920684,0.000063896616,0.00040127343,0.00010513322,0.00014646316,0.000076389224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020532796,0.00007765581,0.00019677776,0.000012384581,0.000032421405,0.0000052085556,0.000078806675,0.00013838186,0.00042811193],"category_scores_gemma":[0.00017615173,0.0000397041,0.0001339103,0.000072794275,0.00013515636,0.000066647786,0.000015763886,0.00036239074,0.0000023078028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018179556,0.00015986002,0.0007243174,0.000023813094,0.000035751153,0.00001927976,0.000058926234,3.227464e-7,0.9961152,0.000031030806,0.0010309804,0.0016187034],"study_design_scores_gemma":[0.00078883534,0.00019777344,0.009042759,0.00003443652,0.000025410274,0.00030256453,0.000117542426,0.000019657762,0.9872316,0.0011523468,0.0010435054,0.000043534237],"about_ca_topic_score_codex":8.0804284e-7,"about_ca_topic_score_gemma":5.240144e-8,"teacher_disagreement_score":0.008883586,"about_ca_system_score_codex":0.000017906985,"about_ca_system_score_gemma":0.00004567818,"threshold_uncertainty_score":0.46875253},"labels":[],"label_agreement":null},{"id":"W1983568583","doi":"10.1111/jcmm.12001","title":"Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development","year":2013,"lang":"en","type":"review","venue":"Journal of Cellular and Molecular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":242,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Necroptosis; Programmed cell death; Autophagy; Apoptosis; Mitotic catastrophe; Cell biology; Mitophagy; Biology; Necrosis; Cancer cell; Mitochondrion; Cancer research; Cell; Signal transduction; Cancer; Genetics","score_opus":0.09207923434546417,"score_gpt":0.368407493686106,"score_spread":0.2763282593406418,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983568583","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0045417314,0.9822151,0.010717146,0.0008893354,0.00021142613,0.001345349,0.000014359567,0.000014187414,0.000051365016],"genre_scores_gemma":[0.0031538324,0.9943615,0.000967326,0.0004108178,0.00063366065,0.00017011359,0.00007111672,0.000066217515,0.00016539708],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99820125,0.000078406316,0.0010062312,0.0002646009,0.0002081675,0.00024134183],"domain_scores_gemma":[0.99821573,0.00017431896,0.00066045846,0.0002397792,0.00029219597,0.00041748458],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035520934,0.00038133375,0.0018396422,0.00035983435,0.00011519471,0.000022770499,0.00013320659,0.00022320604,0.00008401967],"category_scores_gemma":[0.00007870092,0.00024047299,0.0003320415,0.00015875544,0.00014506931,0.00005644404,0.000029654577,0.00037909334,0.0000018660148],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019904863,0.000075333686,0.000020957563,0.003425772,0.0015605476,0.00003215486,0.0002209171,9.04611e-8,0.00255789,0.00021730135,0.00031633276,0.99155277],"study_design_scores_gemma":[0.002449954,0.000828203,0.00032058917,0.010017487,0.0035862988,0.000382547,0.00005695734,0.0000025615873,0.0012213398,0.0006247133,0.98024565,0.00026370602],"about_ca_topic_score_codex":0.000008177689,"about_ca_topic_score_gemma":3.4945143e-7,"teacher_disagreement_score":0.9912891,"about_ca_system_score_codex":0.00008756013,"about_ca_system_score_gemma":0.00057693175,"threshold_uncertainty_score":0.9806204},"labels":[],"label_agreement":null},{"id":"W1984060790","doi":"10.4161/auto.5432","title":"Is mitochondrial generation of reactive oxygen species a trigger for autophagy?","year":2008,"lang":"en","type":"review","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":234,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autophagy; Reactive oxygen species; Superoxide; Cell biology; Peroxynitrite; Programmed cell death; Mitochondrial ROS; Mitochondrion; Biology; Apoptosis; Biochemistry","score_opus":0.14778489750891785,"score_gpt":0.38261203204661776,"score_spread":0.2348271345376999,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984060790","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00024852046,0.9923046,0.00033004442,0.00006519411,0.001323571,0.0034592052,0.0005939796,0.00011786302,0.0015569899],"genre_scores_gemma":[0.000046649835,0.9753604,0.001235032,0.0003256471,0.003589654,0.0006824269,0.0013567975,0.00016196299,0.01724143],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967963,0.00012498564,0.0012432368,0.0008179941,0.000536179,0.0004813038],"domain_scores_gemma":[0.99739,0.000281055,0.0008658645,0.0009335935,0.00030624963,0.00022323697],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000108109285,0.000725526,0.003116593,0.0004199138,0.00016034288,0.000023520293,0.0002966041,0.000742098,0.00073186075],"category_scores_gemma":[0.00016160136,0.00058496214,0.0021040412,0.00041412484,0.00018565623,0.00013304103,0.00005437505,0.00036785254,0.00010933607],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004918361,0.0010371654,9.134665e-7,0.01294492,0.0039854255,0.00024245748,0.0009112522,6.6081833e-7,0.002061843,0.0016231192,0.11387711,0.8628233],"study_design_scores_gemma":[0.0023394153,0.00049415167,0.000032549946,0.0022502106,0.0020292497,0.0002062942,0.000010166494,0.00005262935,0.008287725,0.00012332502,0.98372155,0.00045273133],"about_ca_topic_score_codex":0.0000171475,"about_ca_topic_score_gemma":9.931522e-7,"teacher_disagreement_score":0.86984444,"about_ca_system_score_codex":0.000254317,"about_ca_system_score_gemma":0.00137682,"threshold_uncertainty_score":0.9996602},"labels":[],"label_agreement":null},{"id":"W1984406525","doi":"10.1371/journal.pone.0087064","title":"Novel Analogue of Colchicine Induces Selective Pro-Death Autophagy and Necrosis in Human Cancer Cells","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Colchicine; Autophagy; Pancreatic cancer; Cancer cell; Tubulin; Cancer research; Apoptosis; Cancer; Reactive oxygen species; Microtubule polymerization; Programmed cell death; In vivo; Mitochondrion; Biology; Pharmacology; Microtubule; Chemistry; Biochemistry; Cell biology","score_opus":0.0511133826625507,"score_gpt":0.29007677882453636,"score_spread":0.23896339616198567,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984406525","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978632,0.0005031796,0.000016821992,0.00016904772,0.000014191785,0.00044931684,0.00002495909,0.00002829377,0.00093103485],"genre_scores_gemma":[0.99864334,0.00012599188,0.00038463506,0.00034727104,0.00009840096,0.00006833197,0.000014041232,0.000020566902,0.00029740398],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991277,0.000030374662,0.0002250497,0.00022801194,0.00020779042,0.00018106749],"domain_scores_gemma":[0.9994855,0.000048743954,0.000099573626,0.00016878507,0.00010182063,0.000095599935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012025862,0.00012832461,0.0004368744,0.00013275452,0.00004052934,0.000005908264,0.000058028996,0.000084166764,0.00007699107],"category_scores_gemma":[0.00003133341,0.00011161803,0.000030897772,0.0002099338,0.00007246824,0.000049520986,0.000022670169,0.00016078583,0.0000020796738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012464015,0.0020702109,0.032274213,0.00021542759,0.00030642416,0.0000033462672,0.00055887643,0.000003276484,0.96378154,0.00028376974,0.000023878103,0.0003544158],"study_design_scores_gemma":[0.0019980143,0.00045258534,0.2974676,0.00035256974,0.00020258839,8.339076e-7,0.000018396331,0.00026328588,0.69888085,0.00027287714,0.0000072683642,0.00008309822],"about_ca_topic_score_codex":0.0009400793,"about_ca_topic_score_gemma":0.00012982836,"teacher_disagreement_score":0.2651934,"about_ca_system_score_codex":0.000046250967,"about_ca_system_score_gemma":0.00006800477,"threshold_uncertainty_score":0.4551651},"labels":[],"label_agreement":null},{"id":"W1984469528","doi":"10.1523/jneurosci.1244-13.2014","title":"Regulation of the VHL/HIF-1 Pathway by DJ-1","year":2014,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Ontario Institute for Cancer Research; Queen's University","funders":"Canadian Institutes of Health Research; Ministry of Education, Science and Technology; Heart and Stroke Foundation of Canada; Krembil Foundation; National Research Foundation of Korea; National Research Foundation","keywords":"Hypoxia-inducible factors; Protein subunit; Hypoxia (environmental); Oxidative stress; Biology; Hypoxia-Inducible Factor 1; Neurodegeneration; Context (archaeology); HEK 293 cells; Endocrinology; Cell biology; Internal medicine; Downregulation and upregulation; Gene; Cancer research; Chemistry; Neuroscience; Disease; Genetics; Medicine","score_opus":0.013434988996921556,"score_gpt":0.26062323227228984,"score_spread":0.24718824327536829,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984469528","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968067,0.00010877929,0.0006833446,0.0013237097,0.00046805793,0.00004914459,0.0000015227932,0.0000033981491,0.00055537577],"genre_scores_gemma":[0.9979077,0.000027216038,0.000046359262,0.0014147316,0.00009322064,2.1450332e-7,7.55946e-8,0.0000038887715,0.0005065731],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992089,0.000049940154,0.00021437294,0.00006476295,0.00038312215,0.000078877376],"domain_scores_gemma":[0.99935496,0.00003575594,0.00029410506,0.00016392907,0.00008249082,0.00006878257],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002535057,0.000044830722,0.0001137694,0.000034168726,0.000053757336,0.000007656329,0.00017138151,0.000019733892,0.000014800246],"category_scores_gemma":[0.00024520673,0.00002474866,0.000087600856,0.00019147966,0.00011921799,0.000096083415,0.000016052165,0.000104298546,0.0000011388678],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034373636,0.00006936356,0.0024219507,0.0000062964446,0.0000015131138,0.0000025339327,0.00004242764,0.000021007278,0.99311405,0.00023367723,0.0012954756,0.002757325],"study_design_scores_gemma":[0.00061739254,0.00048657958,0.67096406,0.00006785274,0.000020247313,0.00015123247,0.000009852275,0.0007661436,0.30616507,0.0008506152,0.01986299,0.000037936235],"about_ca_topic_score_codex":7.5788995e-7,"about_ca_topic_score_gemma":7.066597e-8,"teacher_disagreement_score":0.68694896,"about_ca_system_score_codex":0.000010322357,"about_ca_system_score_gemma":0.00007119729,"threshold_uncertainty_score":0.10092211},"labels":[],"label_agreement":null},{"id":"W1984747105","doi":"10.1158/1078-0432.ovca13-a45","title":"Abstract A45: Beclin1-independent autophagy promotes the survival of metastatic ovarian cancer cells","year":2013,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Autophagy; Cell biology; Downregulation and upregulation; ATG5; BAG3; Biology; Autophagosome; Small interfering RNA; Cancer research; Chemistry; Cell culture; Transfection; Apoptosis; Biochemistry","score_opus":0.2438841706056255,"score_gpt":0.5240248442800706,"score_spread":0.28014067367444506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984747105","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9843534,0.0041834856,0.000017573597,0.006962624,0.00075574865,0.0017865903,0.00007211933,0.00004201628,0.0018263994],"genre_scores_gemma":[0.9923805,0.0025601631,0.00009525141,0.00058544945,0.0008099455,0.0006171136,0.000009052043,0.000048452257,0.0028940572],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9957233,0.0006174199,0.000984229,0.0005324755,0.0014496747,0.00069291616],"domain_scores_gemma":[0.9955762,0.002048182,0.00021321967,0.0008617625,0.00084169634,0.00045894575],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0038474018,0.00020686776,0.0006689008,0.00011227877,0.00017957581,0.00005657757,0.000547143,0.00016808648,0.015940033],"category_scores_gemma":[0.00051951036,0.00012512917,0.00034857,0.0004431156,0.000811643,0.00011570778,0.00016843624,0.0013264458,0.00039543945],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0065478696,0.011123371,0.12803465,0.0031229674,0.0075673806,0.00076951744,0.0027489436,0.00016324059,0.1474251,0.003928007,0.08288764,0.6056813],"study_design_scores_gemma":[0.0047626356,0.00089731044,0.91487426,0.00038279683,0.00024283308,0.00000423405,0.00047502274,0.0006157153,0.065693915,0.0039765215,0.007794454,0.00028032408],"about_ca_topic_score_codex":0.0062534227,"about_ca_topic_score_gemma":0.0003005363,"teacher_disagreement_score":0.7868396,"about_ca_system_score_codex":0.00012416265,"about_ca_system_score_gemma":0.0014929681,"threshold_uncertainty_score":0.98495954},"labels":[],"label_agreement":null},{"id":"W1984785884","doi":"10.4161/auto.6.7.13287","title":"Gigantic macroautophagy in programmed nuclear death of<i>Tetrahymena thermophila</i>","year":2010,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research","keywords":"Macronucleus; Tetrahymena; Biology; Autophagy; Cell biology; Cytoplasm; Vacuole; Lysosome; Inner membrane; Autophagosome; Organelle; Ciliate; Genetics; Mitochondrion; Biochemistry; Apoptosis","score_opus":0.008274824722164202,"score_gpt":0.2689016947030741,"score_spread":0.26062686998090995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984785884","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883749,0.0006438176,0.000011205323,0.0003259481,0.00040893303,0.0006582351,0.000009395054,0.00019648668,0.0093711065],"genre_scores_gemma":[0.9971072,0.000081287,0.001095267,0.00087823736,0.00017848774,0.000032250668,0.000018561328,0.00008150898,0.0005271673],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99806225,0.00004793022,0.0005373267,0.0004300822,0.00037828158,0.00054411485],"domain_scores_gemma":[0.9987072,0.00007290717,0.00015261551,0.00073128915,0.000083768275,0.0002522586],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002640583,0.00028917936,0.0005768418,0.00024068989,0.00005852632,0.000022149625,0.00027570437,0.00024397956,0.001042655],"category_scores_gemma":[0.00008039517,0.00025119568,0.00023479719,0.00040076705,0.00019822904,0.00012144334,0.00005836797,0.0005740687,0.00015992965],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008423225,0.0028353548,0.03585985,0.00032357677,0.0003192024,0.0015032875,0.0014290686,0.000004140801,0.8338822,0.0514771,0.00027288529,0.07125102],"study_design_scores_gemma":[0.006614279,0.0007766479,0.71365386,0.00015257022,0.00017163919,0.00031899824,0.000097461656,0.0008106557,0.25923994,0.006343097,0.011306875,0.0005139689],"about_ca_topic_score_codex":0.00012940743,"about_ca_topic_score_gemma":0.000014234327,"teacher_disagreement_score":0.67779404,"about_ca_system_score_codex":0.000034123488,"about_ca_system_score_gemma":0.00017082105,"threshold_uncertainty_score":0.99999404},"labels":[],"label_agreement":null},{"id":"W1988450779","doi":"10.1038/onc.2012.92","title":"The chemotherapeutic agent paclitaxel inhibits autophagy through two distinct mechanisms that regulate apoptosis","year":2012,"lang":"en","type":"article","venue":"Oncogene","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University of Edmonton; University of Alberta","funders":"Alberta Cancer Foundation","keywords":"Paclitaxel; Autophagy; Taxane; Biology; Apoptosis; Cancer research; Autophagosome; Programmed cell death; Docetaxel; Mitosis; Pharmacology; Cell biology; Cancer; Breast cancer; Biochemistry","score_opus":0.04041629530481815,"score_gpt":0.3183055459199637,"score_spread":0.2778892506151455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988450779","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9728207,0.011262483,0.002806655,0.002050621,0.0010028925,0.0007235793,0.000021567683,0.00023491855,0.009076597],"genre_scores_gemma":[0.98983616,0.0007188728,0.0011208495,0.0029561564,0.0006391577,0.00009150515,0.000035705965,0.00008072702,0.0045208465],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99803233,0.00010173674,0.00031441223,0.00031648003,0.0005012004,0.00073381007],"domain_scores_gemma":[0.9985945,0.0001107421,0.0001618921,0.0007712298,0.000058902773,0.00030272422],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041847216,0.00031986515,0.00036486165,0.000035169756,0.00037562463,0.00004209445,0.00019992405,0.00011983776,0.000526088],"category_scores_gemma":[0.000027429222,0.00020670025,0.00027208732,0.00020951674,0.00013953165,0.00016684312,0.000076813405,0.00018640066,0.0003394449],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001381103,0.002275777,0.003448518,0.00019051289,0.0022828912,0.000045782366,0.004265709,0.00000599033,0.7140018,0.04812887,0.0051258625,0.21884719],"study_design_scores_gemma":[0.0023527243,0.00019064132,0.0059373407,0.00007115053,0.00032297283,0.00006543921,0.00018803455,0.00005868841,0.93004453,0.007888262,0.05258579,0.00029440413],"about_ca_topic_score_codex":0.000032461037,"about_ca_topic_score_gemma":0.0000044782237,"teacher_disagreement_score":0.21855278,"about_ca_system_score_codex":0.00015481754,"about_ca_system_score_gemma":0.00008694684,"threshold_uncertainty_score":0.84289914},"labels":[],"label_agreement":null},{"id":"W1988528381","doi":"10.1016/j.bcp.2010.01.019","title":"Synchronised phosphorylation of BNIP3, Bcl-2 and Bcl-xL in response to microtubule-active drugs is JNK-independent and requires a mitotic kinase","year":2010,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research; University of Toronto","funders":"ZonMw; Cancer Research UK","keywords":"Phosphorylation; Mitosis; Cell biology; Kinase; Microtubule; Biology; Autophagy; Microtubule polymerization; Protein kinase B; Protein kinase A; Chemistry; Apoptosis; Biochemistry; Tubulin","score_opus":0.0079215540672481,"score_gpt":0.3040624253495801,"score_spread":0.296140871282332,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988528381","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942137,0.0017914673,0.000005728349,0.0030184586,0.00019623103,0.0006602995,0.000030532865,0.000022601504,0.00006100059],"genre_scores_gemma":[0.9975218,0.00018454611,0.0002285688,0.001755003,0.00010921131,0.000058401518,0.000010211629,0.00001954608,0.000112687936],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99883926,0.00008688337,0.00029133094,0.00038034454,0.0001461963,0.00025599104],"domain_scores_gemma":[0.9991903,0.00021450376,0.00008526454,0.00016267638,0.000067831366,0.0002794356],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022527599,0.00017320945,0.00033090112,0.00015585111,0.00003384777,0.000006285214,0.00007805755,0.00021401017,0.00039953768],"category_scores_gemma":[0.00010055453,0.00016341153,0.000050258277,0.00015159415,0.00025503602,0.000045537945,0.000079577745,0.00029654126,0.000010681002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011894014,0.00035166508,0.0005265183,0.00007727401,0.00007564127,0.00006205946,0.0011239857,2.2688462e-7,0.9787596,0.000009928191,0.004834281,0.002284814],"study_design_scores_gemma":[0.0054584295,0.00031465958,0.034448154,0.00004606377,0.0001097216,0.000029015551,0.00010191712,0.00010664778,0.9570147,0.00012336473,0.002099232,0.00014809343],"about_ca_topic_score_codex":0.00004272691,"about_ca_topic_score_gemma":0.0000014485873,"teacher_disagreement_score":0.033921637,"about_ca_system_score_codex":0.000069282796,"about_ca_system_score_gemma":0.00013588156,"threshold_uncertainty_score":0.6663729},"labels":[],"label_agreement":null},{"id":"W1989974944","doi":"10.4161/auto.8.2.18618","title":"Autophagy can promote but is not required for epithelial cell extrusion in the amnioserosa of the Drosophila embryo","year":2012,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Biology; Cell biology; Embryo; Epithelium; Programmed cell death; Embryonic stem cell; Embryogenesis; Context (archaeology); Apoptosis; Drosophila embryogenesis; Caspase 3; Genetics; Gene","score_opus":0.025619082257953438,"score_gpt":0.28385701414214,"score_spread":0.25823793188418653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989974944","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99224305,0.001117455,0.00003747117,0.002698282,0.00082593906,0.0017929904,0.00019074016,0.000056495148,0.0010375564],"genre_scores_gemma":[0.99101526,0.000072054354,0.0002599506,0.005100603,0.0006653465,0.00017970546,0.000027212747,0.000058750684,0.002621136],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99762434,0.00017961967,0.0005911888,0.00035983723,0.0005632611,0.00068176165],"domain_scores_gemma":[0.99818045,0.00021239009,0.0002910154,0.0010530425,0.00009816555,0.00016492474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074133516,0.0003201284,0.00049252325,0.000106621344,0.00020796171,0.000020808086,0.0005192356,0.0002269876,0.0001910916],"category_scores_gemma":[0.0001245741,0.00018864467,0.00039471113,0.00037782834,0.00020449953,0.00014481525,0.00010702955,0.00029829916,0.000030634626],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008737856,0.0015482238,0.0020158999,0.00034978686,0.00010597437,0.000037500708,0.010305093,0.0000048279358,0.97094995,0.003347327,0.0015244738,0.0089371735],"study_design_scores_gemma":[0.0038327444,0.00032889994,0.14472233,0.00011021822,0.0001643173,0.00004738581,0.00022432831,0.00031566067,0.8427581,0.0014483101,0.005830567,0.00021708928],"about_ca_topic_score_codex":0.00015808518,"about_ca_topic_score_gemma":0.000009436032,"teacher_disagreement_score":0.14270642,"about_ca_system_score_codex":0.0000863924,"about_ca_system_score_gemma":0.00024476837,"threshold_uncertainty_score":0.7692706},"labels":[],"label_agreement":null},{"id":"W1990107870","doi":"10.1371/journal.pone.0112683","title":"Epigallocatechin-3-Gallate Attenuates Impairment of Learning and Memory in Chronic Unpredictable Mild Stress-Treated Rats by Restoring Hippocampal Autophagic Flux","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Libin Cardiovascular Institute of Alberta","funders":"Construct Program of the Key Discipline in Hunan Province; University of South China; National Natural Science Foundation of China","keywords":"Autophagy; Memory impairment; Hippocampal formation; Flux (metallurgy); PI3K/AKT/mTOR pathway; mTORC1; Cell biology; Chemistry; Neuroscience; Medicine; Biology; Signal transduction; Biochemistry; Apoptosis; Cognition","score_opus":0.01664734861115887,"score_gpt":0.24272952906654324,"score_spread":0.22608218045538436,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990107870","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925928,0.0059971167,0.00000873899,0.00019324824,0.000023972923,0.0004362286,0.000011887995,0.00012973892,0.00060627115],"genre_scores_gemma":[0.99701697,0.0007732491,0.00013303662,0.00005929824,0.00011676127,0.000038224964,0.00008582769,0.000044460965,0.0017321627],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983622,0.00012145304,0.00038673138,0.00035338686,0.0003866722,0.00038959045],"domain_scores_gemma":[0.99922943,0.00009822602,0.00014281119,0.00027703375,0.00006166852,0.00019084952],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033218288,0.0002286745,0.0005528303,0.0001558772,0.000075077915,0.000013951243,0.000095122006,0.00012385056,0.00019438335],"category_scores_gemma":[0.000067784254,0.0002121773,0.000054179436,0.00019088386,0.00009953243,0.0000910013,0.000056601148,0.0003421097,0.000020243757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037560417,0.0014100187,0.20898096,0.00083505025,0.0004857631,0.00003556414,0.00050213514,0.00015462298,0.7855813,0.000015542486,0.000114002374,0.0015094223],"study_design_scores_gemma":[0.004560992,0.0014822652,0.04661274,0.001770352,0.00032448955,0.0000040588334,0.000114357805,0.008475402,0.93615735,0.00013140994,0.000100711666,0.00026589638],"about_ca_topic_score_codex":0.00017838867,"about_ca_topic_score_gemma":0.000016761811,"teacher_disagreement_score":0.16236822,"about_ca_system_score_codex":0.00019810574,"about_ca_system_score_gemma":0.000092870585,"threshold_uncertainty_score":0.86523396},"labels":[],"label_agreement":null},{"id":"W1991182145","doi":"10.1158/1538-7445.am10-4832","title":"Abstract 4832: Regulatory role of EF-2 kinase in crosstalk between autophagy and apoptosis and its impact on the activity of a novel AKT inhibitor, MK-2206, against human glioma cells","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University College of the North","funders":"","keywords":"Protein kinase B; Autophagy; PI3K/AKT/mTOR pathway; Cell biology; Cancer research; Biology; Apoptosis; Kinase; Programmed cell death; Phosphorylation; Signal transduction; Biochemistry","score_opus":0.04756728452948548,"score_gpt":0.4047985541618152,"score_spread":0.3572312696323297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991182145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976632,0.0009224257,1.3003645e-7,0.00017503531,0.000037744958,0.0006248329,0.00017363817,0.0000105742665,0.00039243913],"genre_scores_gemma":[0.9995193,0.00012812909,0.0000043124887,0.000022174238,0.00018120269,0.000052671676,0.000004769568,0.000029757091,0.00005770326],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983537,0.00008068549,0.0002618273,0.00032378826,0.0005887219,0.0003912512],"domain_scores_gemma":[0.99865735,0.00036269883,0.00011660291,0.00044557606,0.00018430733,0.00023349797],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009472592,0.00017557124,0.00039107178,0.00030201554,0.00013498274,0.000025595222,0.00016143554,0.00017381829,0.00015937572],"category_scores_gemma":[0.00008817166,0.00012128911,0.00008602577,0.00036271758,0.00054988277,0.00010712344,0.00009840809,0.00075868063,0.0000021530454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005446266,0.00038759116,0.0070275245,0.00014606421,0.00008934666,0.000010687526,0.00045887195,0.0000034983561,0.98390317,0.00013302105,0.00006437184,0.0072312197],"study_design_scores_gemma":[0.0013444694,0.00022751695,0.3523549,0.00016452106,0.000009406608,6.7741695e-7,0.00006204546,0.000027816803,0.64563394,0.000074263306,0.00003539819,0.00006504287],"about_ca_topic_score_codex":0.0008941208,"about_ca_topic_score_gemma":0.000059800255,"teacher_disagreement_score":0.34532738,"about_ca_system_score_codex":0.00010541,"about_ca_system_score_gemma":0.00034502917,"threshold_uncertainty_score":0.49460262},"labels":[],"label_agreement":null},{"id":"W1991836996","doi":"10.1007/s12640-013-9397-0","title":"Induction of Neuronal Mitophagy in Acute Spinal Cord Injury in Rats","year":2013,"lang":"en","type":"article","venue":"Neurotoxicity Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; Canadian Stroke Network","keywords":"Mitophagy; Autophagy; Spinal cord; Cell biology; Downregulation and upregulation; Mitochondrion; Spinal cord injury; Hypoxia (environmental); Chemistry; Biology; Neuroscience; Apoptosis; Biochemistry; Gene","score_opus":0.08493324183076945,"score_gpt":0.43019123852197366,"score_spread":0.3452579966912042,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991836996","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967313,0.000063408144,0.0000024184956,0.00083700026,0.00010159361,0.0015163874,0.0000053940885,0.00001962813,0.0007228601],"genre_scores_gemma":[0.99880856,0.00013911568,0.000045798733,0.00032039933,0.0001130208,0.00023862979,0.0000051976535,0.000022615051,0.00030668985],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9976795,0.00037062328,0.0003739934,0.00035171746,0.0007479405,0.00047626827],"domain_scores_gemma":[0.99914217,0.00007817841,0.00004971672,0.00036621708,0.000192236,0.00017146938],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046511652,0.00012838282,0.00029927248,0.00069386995,0.00004161926,0.000018797014,0.00019884184,0.00012479158,0.00051613356],"category_scores_gemma":[0.00018050971,0.00011924167,0.00006851048,0.0010196667,0.00022415623,0.00018734469,0.00010218923,0.0010024338,0.00012401164],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005008123,0.0009063042,0.052453417,0.000096963966,0.000019417732,0.00023668584,0.000060989598,0.0000019054128,0.91237205,0.000117079006,0.0008036197,0.027923414],"study_design_scores_gemma":[0.0010413207,0.0029211997,0.6961836,0.00007676522,0.000003194756,0.000017971834,0.000025212275,0.00013774192,0.29869848,0.00066676934,0.00016177578,0.000065948065],"about_ca_topic_score_codex":0.0004417098,"about_ca_topic_score_gemma":0.00001482357,"teacher_disagreement_score":0.64373016,"about_ca_system_score_codex":0.000080438054,"about_ca_system_score_gemma":0.00022388663,"threshold_uncertainty_score":0.56513005},"labels":[],"label_agreement":null},{"id":"W1992053460","doi":"10.1371/journal.ppat.1003722","title":"Hepatitis B Virus Disrupts Mitochondrial Dynamics: Induces Fission and Mitophagy to Attenuate Apoptosis","year":2013,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":307,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Institute of General Medical Sciences; National Institutes of Health; Deutsche Forschungsgemeinschaft; University of Southern California","keywords":"Mitophagy; MFN2; Parkin; Mitochondrial fission; PINK1; Biology; Cell biology; Mitochondrion; MFN1; DNAJA3; HBx; mitochondrial fusion; DNM1L; Autophagy; Mitochondrial DNA; Virology; Hepatitis B virus; Apoptosis; Virus; Genetics","score_opus":0.012967642669393388,"score_gpt":0.2521789470086719,"score_spread":0.2392113043392785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992053460","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967283,0.00027167433,0.00007779237,0.0010626424,0.00032531534,0.00086023676,0.0001520031,0.00010807708,0.0004139625],"genre_scores_gemma":[0.9949412,0.00041339456,0.0015187004,0.0017413386,0.0005131762,0.00021304876,0.00008009521,0.00004914022,0.0005299437],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986136,0.00005556605,0.00026840006,0.00041411543,0.00030097945,0.00034733576],"domain_scores_gemma":[0.9989477,0.00006132593,0.00006858673,0.00036500944,0.00010654336,0.00045085402],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000358644,0.00023470877,0.00035740202,0.00012938344,0.000128414,0.00005160855,0.00009954801,0.00013853183,0.0006725307],"category_scores_gemma":[0.00009955821,0.00019412799,0.00010225192,0.00017518677,0.00005343023,0.0001337689,0.00007873933,0.00014442019,0.000516033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012373824,0.00034422407,0.030884502,0.00006363147,0.0001587268,0.000058196452,0.00079109793,6.297095e-7,0.94115955,0.000045238015,0.001677343,0.02469311],"study_design_scores_gemma":[0.0028671878,0.001120301,0.40664598,0.00043129837,0.00040356288,0.000043194774,0.00031846622,0.0025316654,0.5829834,0.000850075,0.0010533895,0.0007515016],"about_ca_topic_score_codex":0.0005736631,"about_ca_topic_score_gemma":0.00007234783,"teacher_disagreement_score":0.37576148,"about_ca_system_score_codex":0.00006886819,"about_ca_system_score_gemma":0.000041725107,"threshold_uncertainty_score":0.791631},"labels":[],"label_agreement":null},{"id":"W1993098682","doi":"10.1016/j.tins.2014.03.004","title":"Parkin and PINK1: much more than mitophagy","year":2014,"lang":"en","type":"review","venue":"Trends in Neurosciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":398,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute on Drug Abuse; Canadian Institutes of Health Research","keywords":"PINK1; Parkin; Mitophagy; Autophagy; Tensin; Biology; Mitochondrion; LRRK2; Parkinson's disease; Disease; PTEN; Genetics; Neuroscience; Cell biology; Bioinformatics; Medicine; PI3K/AKT/mTOR pathway; Pathology; Signal transduction","score_opus":0.06801179739807535,"score_gpt":0.41581028216599286,"score_spread":0.3477984847679175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993098682","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0022068408,0.9944922,0.0000015638424,0.00012201285,0.00083349494,0.00020268097,0.000016310536,0.000057720987,0.002067215],"genre_scores_gemma":[0.0033767845,0.9924528,0.000030510484,0.00035782598,0.00025093314,0.00005590372,0.00002216595,0.000030886997,0.0034222014],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99798244,0.000122534,0.0004401899,0.0007145461,0.00036615727,0.00037414525],"domain_scores_gemma":[0.99902636,0.00013524349,0.00018987458,0.00043161717,0.000011845379,0.00020506546],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002269185,0.000369673,0.0013138284,0.0005998642,0.000084152605,0.00005100338,0.00031849457,0.000179671,0.00009517543],"category_scores_gemma":[0.000065559034,0.00024985758,0.00025547165,0.00094616925,0.00044969382,0.00007151205,0.00007880801,0.00034547248,0.000014442394],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000068042214,0.00008915726,0.0002594169,0.0014919024,0.000012601205,0.00015440346,0.000043319447,7.216482e-8,0.0000037746481,0.00007416127,0.00038275463,0.99748164],"study_design_scores_gemma":[0.00036658472,0.0002548389,0.0038934373,0.0026396478,0.00021729097,0.00018082165,0.000011178952,0.000030826835,0.000010522352,0.00006709994,0.9920599,0.0002678412],"about_ca_topic_score_codex":0.000016497817,"about_ca_topic_score_gemma":0.000007044946,"teacher_disagreement_score":0.9972138,"about_ca_system_score_codex":0.000024058261,"about_ca_system_score_gemma":0.00011952212,"threshold_uncertainty_score":0.99999535},"labels":[],"label_agreement":null},{"id":"W1993332233","doi":"10.1016/j.radonc.2009.06.029","title":"Autophagy is required during cycling hypoxia to lower production of reactive oxygen species","year":2009,"lang":"en","type":"article","venue":"Radiotherapy and Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":139,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Autophagy; Reactive oxygen species; Mitochondrial ROS; Hypoxia (environmental); Cell biology; Programmed cell death; Viability assay; Chemistry; Apoptosis; Mitochondrion; Oxidative stress; Biology; Biochemistry; Oxygen","score_opus":0.018599533717949167,"score_gpt":0.3097211676575904,"score_spread":0.29112163393964124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993332233","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98974437,0.0022518206,0.00010750164,0.0054722107,0.00034909358,0.00041768627,0.0000031781453,0.000054995708,0.0015991459],"genre_scores_gemma":[0.9903554,0.001531965,0.0016546621,0.0029763835,0.0006730478,0.00001106867,0.000003681486,0.000017323715,0.0027764845],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990326,0.000046398887,0.00026289668,0.00031091183,0.0001284437,0.000218741],"domain_scores_gemma":[0.9994199,0.000035158148,0.00010723644,0.00024302248,0.00006305424,0.00013160038],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013677047,0.00014450126,0.0004302785,0.00014216713,0.00008528103,0.0000058510063,0.000057757105,0.00013530544,0.00020482187],"category_scores_gemma":[0.000034006862,0.00012638354,0.00008500791,0.00017022563,0.00008543905,0.00008652796,0.000007669219,0.00011417776,0.0000044473513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032384244,0.0004283716,0.00046376366,0.000028721604,0.00017592263,0.00007571061,0.0034807194,0.000008727995,0.95847213,0.00029306172,0.0007500807,0.032584377],"study_design_scores_gemma":[0.0035556264,0.004236413,0.41679808,0.00010359685,0.00009126321,0.00024707484,0.00025827336,0.000044264187,0.53019255,0.0008053832,0.04343188,0.00023558042],"about_ca_topic_score_codex":0.0000074782415,"about_ca_topic_score_gemma":0.0000020577652,"teacher_disagreement_score":0.42827955,"about_ca_system_score_codex":0.00023491205,"about_ca_system_score_gemma":0.000087203865,"threshold_uncertainty_score":0.5153771},"labels":[],"label_agreement":null},{"id":"W1994361191","doi":"10.1051/medsci/20092511906","title":"Contribution de l’autophagie dans l’apprêtement d’antigènes viraux endogènes","year":2009,"lang":"fr","type":"article","venue":"médecine/sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Molecular biology; Chemistry; Biology","score_opus":0.02831637183782061,"score_gpt":0.33187568801451756,"score_spread":0.30355931617669696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994361191","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83436,0.108281806,0.0050056055,0.019362096,0.0029214462,0.000842631,0.000078730496,0.00024026631,0.02890742],"genre_scores_gemma":[0.98442465,0.0038748581,0.0008568899,0.0042293887,0.0020893102,0.000030137591,0.000027157746,0.00002108303,0.0044465135],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"observational","domain_scores_codex":[0.99594855,0.00026754482,0.00068982283,0.0007977256,0.00079224206,0.0015041131],"domain_scores_gemma":[0.99838424,0.00029248305,0.00025858634,0.00042990845,0.00015896968,0.0004758057],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0016338843,0.00048556848,0.0006349693,0.00025885933,0.0008844261,0.00017828746,0.0005816522,0.00025111227,0.0013163278],"category_scores_gemma":[0.0003699476,0.00041497196,0.00029932155,0.0009549274,0.0013355152,0.00047602598,0.000059064485,0.0002940035,0.00042303264],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038837068,0.0044792206,0.06062956,0.00019526342,0.00037414365,0.00134404,0.0019069534,0.00081311585,0.11294929,0.7055525,0.013417947,0.09794958],"study_design_scores_gemma":[0.010625846,0.0070608603,0.53229785,0.0017331927,0.0009442477,0.0006807896,0.0028608686,0.011746606,0.24856521,0.1108689,0.07126297,0.0013526315],"about_ca_topic_score_codex":0.00017494081,"about_ca_topic_score_gemma":0.000016076814,"teacher_disagreement_score":0.5946836,"about_ca_system_score_codex":0.00033976405,"about_ca_system_score_gemma":0.0008234175,"threshold_uncertainty_score":0.9998302},"labels":[],"label_agreement":null},{"id":"W1994408958","doi":"10.4161/auto.32154","title":"Autophagy is not required to sustain exercise and PRKAA1/AMPK activity but is important to prevent mitochondrial damage during physical activity","year":2014,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":144,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Consiglio Nazionale delle Ricerche; Fondazione Telethon; Fondation Leducq","keywords":"Autophagy; AMPK; Biology; Skeletal muscle; Mitochondrion; Cell biology; Homeostasis; Endocrinology; Biochemistry; Protein kinase A; Apoptosis; Phosphorylation","score_opus":0.012042184771283498,"score_gpt":0.29355576174131204,"score_spread":0.28151357697002855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994408958","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99365765,0.00010591639,0.00038302495,0.0027020692,0.0004325713,0.0020385205,0.00010393777,0.00029146348,0.00028487697],"genre_scores_gemma":[0.98990756,0.00005522797,0.0005051293,0.0022029374,0.0010064774,0.00025526315,0.000009706022,0.000110310044,0.0059473854],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964098,0.00015832162,0.00042985546,0.0012564912,0.00077450543,0.0009710595],"domain_scores_gemma":[0.997074,0.00014199511,0.00021723824,0.0012916061,0.00014037403,0.0011347757],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028355655,0.0006202253,0.0010880843,0.000268199,0.00029693262,0.000100875746,0.00030752516,0.00025009262,0.0002974829],"category_scores_gemma":[0.00021516513,0.0005789702,0.00033544409,0.00044420813,0.00012194428,0.000361068,0.00035409292,0.0004121243,0.00016896786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004523395,0.0022073567,0.00030619855,0.00035230402,0.00025361875,0.00035321902,0.0040639304,0.0000096227595,0.93789446,0.00026340954,0.0021203724,0.047652133],"study_design_scores_gemma":[0.0030935192,0.00077933463,0.1287426,0.00019504606,0.00023647673,0.000028115515,0.00006246086,0.0015788825,0.8619571,0.00035720196,0.002414127,0.00055516895],"about_ca_topic_score_codex":0.00026239696,"about_ca_topic_score_gemma":0.000008759533,"teacher_disagreement_score":0.12843642,"about_ca_system_score_codex":0.00024979547,"about_ca_system_score_gemma":0.00024929567,"threshold_uncertainty_score":0.99966615},"labels":[],"label_agreement":null},{"id":"W1994561839","doi":"10.1038/nature12555","title":"A table for two","year":2013,"lang":"en","type":"letter","venue":"Nature","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Parkin; Mitophagy; Autophagy; Ubiquitin ligase; Phagosome; Ubiquitin; Cell biology; Biology; Mitochondrion; Innate immune system; Immune system; Intracellular; Genetics; Gene; Medicine","score_opus":0.009467898720505267,"score_gpt":0.30163540943867534,"score_spread":0.2921675107181701,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994561839","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000744318,0.013650508,0.00004201795,0.97232,0.0012080554,0.0013514444,0.00021017282,0.00013039434,0.010343098],"genre_scores_gemma":[0.00064593105,0.000038099002,0.0004611397,0.8903142,0.011593077,0.00017482993,0.001242166,0.000060980452,0.095469564],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99916255,0.000009366015,0.00010389585,0.00024809057,0.00021490108,0.0002612029],"domain_scores_gemma":[0.9993362,0.000056046232,0.000059983267,0.00036376863,0.00013105535,0.00005297466],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00003363685,0.00018638768,0.0003123296,0.00006253578,0.000036802387,0.000018420928,0.00011629571,0.004112849,0.001281796],"category_scores_gemma":[0.00003593829,0.00013771545,0.00018104713,0.0000691501,0.000020854437,0.00003033833,0.000012443113,0.0057296087,0.00018250672],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032995733,0.000017787801,0.000009534671,0.0002260569,0.00014755229,0.00014647483,0.000009878419,4.8868156e-8,0.00012321082,0.000074944146,0.9982935,0.0009179782],"study_design_scores_gemma":[0.001289628,0.00007199783,0.00005934156,0.00010913976,0.00017296348,0.000025091103,0.0000016303186,0.000017423683,0.0007775258,0.0011975509,0.996138,0.00013973402],"about_ca_topic_score_codex":0.000007689256,"about_ca_topic_score_gemma":3.5581115e-7,"teacher_disagreement_score":0.08512647,"about_ca_system_score_codex":0.00002685446,"about_ca_system_score_gemma":0.0001281001,"threshold_uncertainty_score":0.99963117},"labels":[],"label_agreement":null},{"id":"W1994686763","doi":"10.1016/j.bbrc.2010.07.033","title":"Oxidative stress alters the regulatory control of p66Shc and Akt in PINK1 deficient cells","year":2010,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Oxidative stress; PINK1; Phosphorylation; Oxidative phosphorylation; Protein kinase B; Cell biology; Biology; Reactive oxygen species; Peroxiredoxin; Transfection; Mitochondrion; Biochemistry; Apoptosis; Enzyme; Mitophagy; Gene; Peroxidase; Autophagy","score_opus":0.03726041012307391,"score_gpt":0.3608373328997149,"score_spread":0.323576922776641,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994686763","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937023,0.0011190845,0.000010187542,0.0044588996,0.000010414807,0.00034805856,0.000044072014,0.000007919994,0.0002990947],"genre_scores_gemma":[0.9990191,0.0005537535,0.00016295971,0.0001223366,0.000034269095,0.000047861035,0.0000173236,0.0000063249768,0.00003606098],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990384,0.00014720851,0.00016931226,0.00016635242,0.0002834987,0.00019522614],"domain_scores_gemma":[0.99806184,0.000774309,0.000034501263,0.0008203809,0.00015381616,0.00015513609],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000371441,0.000078629826,0.00016772361,0.00006387572,0.00013173833,0.000015232475,0.00031448095,0.000074755255,0.000012473616],"category_scores_gemma":[0.00016897904,0.000049504833,0.00004464331,0.0002471437,0.00205576,0.000026959318,0.00020737313,0.00061535445,0.000003656117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011408955,0.0005593721,0.00065448444,0.000029033034,0.000023711087,8.929188e-7,0.00017612624,6.4016554e-8,0.98935837,0.0071981465,0.00014182893,0.0017438822],"study_design_scores_gemma":[0.0011333815,0.00018240286,0.0387249,0.000087479944,0.000027067572,0.0000020553678,0.0003501255,0.0010178465,0.9558334,0.0017249133,0.00083392207,0.00008250569],"about_ca_topic_score_codex":0.000077469376,"about_ca_topic_score_gemma":0.000009432422,"teacher_disagreement_score":0.038070414,"about_ca_system_score_codex":0.000014001759,"about_ca_system_score_gemma":0.00007599202,"threshold_uncertainty_score":0.7574533},"labels":[],"label_agreement":null},{"id":"W1994772532","doi":"10.4161/auto.5278","title":"Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3","year":2008,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":352,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; CancerCare Manitoba Foundation","keywords":"Autophagy; Biology; Programmed cell death; Apoptosis; Hypoxia (environmental); Cell biology; Cell culture; Cell; Cancer research; Cancer cell; Cancer; Biochemistry; Oxygen; Chemistry; Genetics","score_opus":0.03524847234623597,"score_gpt":0.265384619361262,"score_spread":0.23013614701502605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994772532","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98725444,0.0036030612,0.00022398442,0.00018386637,0.0006447773,0.0007286948,0.000011438992,0.00032719303,0.00702254],"genre_scores_gemma":[0.9892459,0.0014657573,0.003663976,0.0028902714,0.00027773244,0.000108190594,0.00003050639,0.000094032504,0.0022236286],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99698526,0.0001362778,0.0006878072,0.00075514003,0.00060401903,0.0008314872],"domain_scores_gemma":[0.99853927,0.00012995653,0.00020309961,0.0007412443,0.000089944224,0.00029649184],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002304809,0.00049974065,0.00077653903,0.00028122382,0.000229523,0.00003039497,0.00034321568,0.0003099936,0.0007334105],"category_scores_gemma":[0.00003363389,0.0004592963,0.00030392516,0.000529817,0.00012006649,0.00033481725,0.00012261092,0.0005465904,0.0005014754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026495708,0.002330397,0.0015890788,0.00024897876,0.00021043261,0.002367272,0.0056410786,0.000059583854,0.97065157,0.014901056,0.0009896434,0.0007459489],"study_design_scores_gemma":[0.0040621236,0.0004333832,0.032720014,0.0001459038,0.000100805555,0.00014822873,0.00023782949,0.0006278871,0.9525172,0.007398788,0.0010971045,0.0005106936],"about_ca_topic_score_codex":0.0003132386,"about_ca_topic_score_gemma":0.0000053387366,"teacher_disagreement_score":0.031130936,"about_ca_system_score_codex":0.00023062537,"about_ca_system_score_gemma":0.00039435618,"threshold_uncertainty_score":0.9997859},"labels":[],"label_agreement":null},{"id":"W1995200161","doi":"10.1007/s11033-012-1975-3","title":"ATF4 orchestrates a program of BH3-only protein expression in severe hypoxia","year":2012,"lang":"en","type":"article","venue":"Molecular Biology Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; National Institute for Health and Care Research; Natural Sciences and Engineering Research Council of Canada; Cancer Research UK","keywords":"ATF4; Gene knockdown; Autophagy; Hypoxia (environmental); RNA interference; Cell biology; Biology; Cancer research; Mediator; Transcription factor; Small interfering RNA; Transcription (linguistics); RNA; Unfolded protein response; Chemistry; Apoptosis; Gene; Genetics","score_opus":0.01211331102707647,"score_gpt":0.3162000415066826,"score_spread":0.30408673047960616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995200161","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950774,0.0025373069,0.00013114265,0.000078700235,0.00008394574,0.00093690644,0.0000016536243,0.00005694287,0.0010960249],"genre_scores_gemma":[0.9965387,0.000011015738,0.0028950472,0.00011398486,0.000036014902,0.00016420126,0.000059726306,0.000018559906,0.0001627738],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989042,0.000087356435,0.000371676,0.00023081175,0.00010043491,0.0003054768],"domain_scores_gemma":[0.99925065,0.000010469645,0.00018784929,0.00037733826,0.000046496592,0.00012717383],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024203777,0.00014078687,0.00029789022,0.000081595215,0.000016558395,0.0000025047323,0.000044422562,0.00020418235,0.00007069482],"category_scores_gemma":[0.00009262253,0.00010869176,0.000098419645,0.00014061623,0.00010622668,0.00003850784,0.000036227728,0.00013888205,0.0000043923123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009865509,0.000666856,0.18764032,0.000053618514,0.00004248505,0.0008891377,0.00008341531,4.866882e-7,0.803292,0.000107353844,0.00003005075,0.007095647],"study_design_scores_gemma":[0.0006691404,0.00047647976,0.1721107,0.00017926676,0.000038149607,0.0012595558,0.000033367905,0.0000045451466,0.82160443,0.0018500413,0.001617186,0.00015716345],"about_ca_topic_score_codex":0.000018690753,"about_ca_topic_score_gemma":7.756783e-7,"teacher_disagreement_score":0.018312426,"about_ca_system_score_codex":0.000019563466,"about_ca_system_score_gemma":0.00013472741,"threshold_uncertainty_score":0.44323212},"labels":[],"label_agreement":null},{"id":"W1995412458","doi":"10.1073/pnas.0812745106","title":"DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses","year":2009,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":220,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Princess Margaret Cancer Centre","funders":"Canadian Institutes of Health Research; Ligue Contre le Cancer","keywords":"PI3K/AKT/mTOR pathway; Protein kinase B; Biology; Cell biology; Regulator; Hypoxia (environmental); Transcription factor; Mediator; Cellular adaptation; Cancer research; AMPK; Activator (genetics); Cell growth; Signal transduction; Gene; Chemistry; Genetics; Phosphorylation; Protein kinase A","score_opus":0.05882280556464197,"score_gpt":0.34469893503575155,"score_spread":0.2858761294711096,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995412458","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99327993,0.0004107406,1.6166616e-7,0.004437177,0.000015840993,0.00018492476,0.000017360317,0.000012222356,0.0016416654],"genre_scores_gemma":[0.99799037,0.000071865565,0.00052056473,0.001182528,0.00010857437,0.0000031856891,2.3289577e-7,0.000003897909,0.00011877535],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978029,0.0000073074825,0.00045380165,0.00021742018,0.0013737471,0.00014479978],"domain_scores_gemma":[0.99898785,0.00007042692,0.0005269274,0.000016730815,0.00031288667,0.00008517921],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011951134,0.00009976065,0.00023660096,0.00018998656,0.000094471274,0.0000074526247,0.0004834485,0.000093168004,0.00006570317],"category_scores_gemma":[0.0004673844,0.00006326427,0.0001122723,0.0005854763,0.00043966016,0.0002967857,0.00003032595,0.00012555631,7.6497474e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017193651,0.00016621708,0.0055053947,0.00003265544,0.000021937802,5.1422937e-8,0.00035566863,7.3818217e-7,0.9830424,0.009953775,0.0003453243,0.00040387383],"study_design_scores_gemma":[0.0003067684,0.00030816608,0.15454403,0.00007060425,0.000030174499,0.0000047498133,0.00018110477,0.00020163455,0.8171702,0.027042653,0.000085383326,0.000054538923],"about_ca_topic_score_codex":0.0000030039087,"about_ca_topic_score_gemma":9.884328e-9,"teacher_disagreement_score":0.16587223,"about_ca_system_score_codex":0.000019984353,"about_ca_system_score_gemma":0.00012054747,"threshold_uncertainty_score":0.25798422},"labels":[],"label_agreement":null},{"id":"W1995487745","doi":"10.1074/jbc.m114.604603","title":"The Essential Autophagy Gene ATG7 Modulates Organ Fibrosis via Regulation of Endothelial-to-Mesenchymal Transition","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":120,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"University of Toronto; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Extracellular matrix; Mesenchymal stem cell; Fibrosis; Fibroblast; Cell biology; Pulmonary fibrosis; Biology; Cancer research; Epithelial–mesenchymal transition; Myofibroblast; Cardiac fibrosis; Pathology; Downregulation and upregulation; Medicine; In vitro; Gene; Genetics; Apoptosis","score_opus":0.008491750018638384,"score_gpt":0.24243377905709987,"score_spread":0.23394202903846148,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995487745","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943422,0.00028471008,0.004328564,0.0007042657,0.00008519194,0.00007867785,0.000009479731,0.000013514685,0.00015339952],"genre_scores_gemma":[0.9982059,0.00010596213,0.00067676033,0.00013877414,0.0007630731,0.0000018286721,0.000013593911,0.000008616748,0.00008546632],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898046,0.000051699502,0.0004597235,0.00012057413,0.00023293057,0.00015461522],"domain_scores_gemma":[0.9991107,0.00011780278,0.00027784143,0.00016604333,0.00017778165,0.00014982223],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030524397,0.000116424446,0.00029508685,0.000021367252,0.00007372171,0.000010842455,0.00012965912,0.0001551512,0.00026065516],"category_scores_gemma":[0.00014248997,0.00006526422,0.00022033128,0.00010154821,0.000114201655,0.000033884025,0.00001591204,0.00015825547,0.0000043333607],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007671045,0.0001120397,0.0002445047,0.000027231335,0.000076029864,0.000006937673,0.00005528165,0.000085869644,0.9947965,0.00001660011,0.00006825308,0.0037436185],"study_design_scores_gemma":[0.0009104338,0.0004117559,0.024047395,0.00004910411,0.0000610337,0.00014363155,0.000022461423,0.00058811053,0.97203046,0.0012361289,0.00043054117,0.00006897341],"about_ca_topic_score_codex":0.0000019091524,"about_ca_topic_score_gemma":6.275845e-8,"teacher_disagreement_score":0.02380289,"about_ca_system_score_codex":0.000030293775,"about_ca_system_score_gemma":0.00004184513,"threshold_uncertainty_score":0.2853991},"labels":[],"label_agreement":null},{"id":"W1996626530","doi":"10.1002/path.4100","title":"Autophagy in clear cell ovarian cancer, a potential marker for hypoxia and poor prognosis?<sup>#</sup>","year":2012,"lang":"en","type":"letter","venue":"The Journal of Pathology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Autophagy; Ovarian cancer; Hypoxia (environmental); Cancer research; Biomarker; Oncology; Biology; Pathological; Cell; Internal medicine; Cancer; Medicine; Apoptosis; Chemistry; Genetics","score_opus":0.015489800777421545,"score_gpt":0.2714940157533138,"score_spread":0.2560042149758922,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996626530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7138577,0.019414274,0.00024489086,0.26406506,0.00096557435,0.0011315544,0.0000989913,0.000019806012,0.00020212974],"genre_scores_gemma":[0.62535614,0.004099166,0.0013429316,0.35371688,0.012796181,0.000095659336,0.00004597658,0.00017589958,0.0023711647],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99782914,0.00045271922,0.00066729775,0.0002060777,0.0002830329,0.00056176196],"domain_scores_gemma":[0.9986389,0.00021329324,0.00060975156,0.00025047956,0.00015339482,0.00013416253],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010089906,0.00031957822,0.0008464286,0.0002860215,0.00007887828,0.000015658688,0.00027654044,0.00071907265,0.00035044915],"category_scores_gemma":[0.00004884683,0.00020603184,0.0002724504,0.00009900048,0.00020576855,0.000081938386,0.00006069729,0.0017269271,0.000010107429],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011600956,0.0010062732,0.0027318273,0.001485855,0.0012408264,0.020628227,0.0036474448,0.00006771042,0.01597246,0.00003819809,0.926756,0.014824168],"study_design_scores_gemma":[0.03349225,0.0068546007,0.113244206,0.0013861691,0.009047435,0.04012056,0.0006700857,0.0014509337,0.004476207,0.0039673904,0.7838495,0.0014406899],"about_ca_topic_score_codex":0.000024394516,"about_ca_topic_score_gemma":0.000001893101,"teacher_disagreement_score":0.14290658,"about_ca_system_score_codex":0.00008286426,"about_ca_system_score_gemma":0.0002854527,"threshold_uncertainty_score":0.8401735},"labels":[],"label_agreement":null},{"id":"W1996936400","doi":"10.4161/auto.19315","title":"ATG5, autophagy and lung function in asthma","year":2012,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Université du Québec à Chicoutimi; Christie (Canada); McGill University Health Centre","funders":"","keywords":"Biology; Autophagy; ATG5; Asthma; Lung function; Lung; Function (biology); Immunology; Cell biology; Internal medicine; Genetics; Apoptosis; Medicine","score_opus":0.009422482935483388,"score_gpt":0.2730094746016634,"score_spread":0.26358699166618005,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996936400","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97955036,0.013592538,0.0002537904,0.0002049689,0.00050921616,0.000313103,0.000003488086,0.00014918693,0.005423367],"genre_scores_gemma":[0.9955457,0.00019657935,0.00022355643,0.0014680987,0.00045115245,0.000041061998,0.000022483375,0.00003527919,0.0020161052],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998728,0.00005502576,0.00026573395,0.0002572568,0.00021301513,0.0004810113],"domain_scores_gemma":[0.9992775,0.00005437111,0.00006068392,0.00029136438,0.000029540624,0.00028659217],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025979438,0.00019551454,0.0003006424,0.00017633609,0.00006571169,0.000016528144,0.00005592671,0.00014819899,0.0008760873],"category_scores_gemma":[0.00003881121,0.00017663726,0.00007747453,0.00024081596,0.000066834975,0.0002874432,0.000042489195,0.00021124432,0.0001614269],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026039034,0.0036596013,0.5327427,0.0008210495,0.00090612104,0.00078564364,0.005625656,0.000023594333,0.08083935,0.06069912,0.011253557,0.30003974],"study_design_scores_gemma":[0.0023654876,0.00018866167,0.96763796,0.000056255598,0.00007555295,0.00012334473,0.0000759675,0.0007820701,0.01242857,0.00053643255,0.015529976,0.00019974676],"about_ca_topic_score_codex":0.000044036053,"about_ca_topic_score_gemma":0.0000039054157,"teacher_disagreement_score":0.43489528,"about_ca_system_score_codex":0.00008202658,"about_ca_system_score_gemma":0.000058632846,"threshold_uncertainty_score":0.95925415},"labels":[],"label_agreement":null},{"id":"W1997088801","doi":"10.4161/auto.7.2.14224","title":"Mutant ataxin-3 promotes the autophagic degradation of parkin","year":2011,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"","keywords":"Parkin; Autophagy; PINK1; Biology; Neurodegeneration; Neuroprotection; Cell biology; Mutant; Parkinson's disease; Ubiquitin; Neuroscience; Genetics; Mitophagy; Disease; Internal medicine; Apoptosis; Medicine; Gene","score_opus":0.040313760485096314,"score_gpt":0.2664801004034673,"score_spread":0.22616633991837098,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997088801","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888885,0.0016635843,0.00028754058,0.00022500097,0.00019978311,0.0005215819,0.000011501774,0.00011914407,0.008083343],"genre_scores_gemma":[0.99707633,0.00008024319,0.00068687747,0.00046685978,0.000087113855,0.0000406543,0.000021213313,0.00002702885,0.001513675],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99882275,0.00006819145,0.00034817125,0.00023439997,0.00027995967,0.00024654018],"domain_scores_gemma":[0.9990006,0.000060104107,0.00017008136,0.0005756997,0.000092931,0.00010055431],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00023536434,0.00016882124,0.00027771638,0.00007439134,0.000083448045,0.000007672758,0.00019998912,0.0000870471,0.0014140869],"category_scores_gemma":[0.000066582565,0.000105967025,0.00015235721,0.00023907084,0.00017652079,0.000092545626,0.00003985657,0.00014680308,0.00011228031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002968613,0.00589314,0.030080663,0.0008169667,0.0029505957,0.0013677558,0.016986255,0.000006285077,0.5330671,0.13136214,0.003353558,0.27114692],"study_design_scores_gemma":[0.0013740518,0.00045794548,0.22026739,0.00006802398,0.00023044404,0.000101374215,0.00012005208,0.00042287246,0.77003634,0.004353743,0.0024146892,0.00015308693],"about_ca_topic_score_codex":0.00010337635,"about_ca_topic_score_gemma":0.0000038018516,"teacher_disagreement_score":0.27099383,"about_ca_system_score_codex":0.000026807402,"about_ca_system_score_gemma":0.00013328574,"threshold_uncertainty_score":0.9994988},"labels":[],"label_agreement":null},{"id":"W1997563278","doi":"10.1158/1538-7445.am2011-3836","title":"Abstract 3836: Identification of PTPsigma as an autophagic phosphatase","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University; McGill University","funders":"","keywords":"Autophagy; Phosphatase; Phosphatidylinositol; Cell biology; Lysosome; Kinase; Protein tyrosine phosphatase; Vesicle; Biology; Chemistry; Biochemistry; Phosphorylation; Enzyme; Membrane; Apoptosis","score_opus":0.14615071680931138,"score_gpt":0.45624520722056755,"score_spread":0.31009449041125614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997563278","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99003106,0.004432021,0.000010211823,0.000113837326,0.00011489197,0.00039396845,0.000045637564,0.000040820723,0.004817551],"genre_scores_gemma":[0.9974112,0.000738627,0.000035807363,0.00010278701,0.00013575795,0.00011275246,0.00004501121,0.00002368454,0.0013943898],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985384,0.000061864346,0.00026684627,0.00027584084,0.0005640293,0.0002930384],"domain_scores_gemma":[0.9986976,0.00003605141,0.00007192164,0.00060202513,0.00034580857,0.00024660298],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007161425,0.00008696397,0.00016573667,0.00016630442,0.00008316979,0.000013500609,0.00021832877,0.0000761836,0.0069800653],"category_scores_gemma":[0.00007987515,0.00007589305,0.00006097351,0.0003131242,0.00022053237,0.00016755919,0.00003064423,0.00024996675,0.00032695534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0046176324,0.0028982074,0.010441357,0.0008027469,0.00041480522,0.0006244017,0.0059710443,0.0000042335373,0.81268954,0.020028366,0.0067454805,0.13476221],"study_design_scores_gemma":[0.00078389124,0.0002462856,0.21427178,0.00006730485,0.000021902677,0.000004627186,0.00021660376,0.000023324023,0.7797023,0.0034141038,0.0011786383,0.00006925225],"about_ca_topic_score_codex":0.0012444102,"about_ca_topic_score_gemma":0.000011652755,"teacher_disagreement_score":0.20383042,"about_ca_system_score_codex":0.000086424,"about_ca_system_score_gemma":0.00044174684,"threshold_uncertainty_score":0.9939277},"labels":[],"label_agreement":null},{"id":"W1998068719","doi":"10.1038/nrm3249","title":"Canonical and non-canonical autophagy: variations on a common theme of self-eating?","year":2011,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":532,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institut National Du Cancer; Institute of Cancer Research; Institut National de la Santé et de la Recherche Médicale; Université Paris-Sud; Agence Nationale de la Recherche","keywords":"Non canonical; Autophagy; Canonical correspondence analysis; Canonical correlation; Canonical analysis; Theme (computing); Chemistry; Biology; Psychology; Mathematics; Biochemistry; Cell biology; Ecology; Computer science; Statistics; World Wide Web","score_opus":0.022221601579140545,"score_gpt":0.34882167840453865,"score_spread":0.3266000768253981,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998068719","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001256004,0.98478764,0.000048547536,0.0000247065,0.0002144292,0.0023283884,0.0000645508,0.00004681462,0.012359346],"genre_scores_gemma":[0.001417627,0.994862,0.0017588113,0.0010363994,0.00015577901,0.0002184017,0.00036019378,0.00008033119,0.00011044666],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966298,0.00082992297,0.0012161696,0.0007711545,0.00015058574,0.00040239538],"domain_scores_gemma":[0.99741644,0.00027510658,0.0008723587,0.0010910252,0.00008048583,0.00026456369],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00052944414,0.00068213145,0.0040184907,0.00021803458,0.00006139375,0.0000077332925,0.00036546995,0.0021247119,0.00018602794],"category_scores_gemma":[0.00016194448,0.00044733,0.0011398462,0.00035402048,0.00016419265,0.000015948734,0.0001369445,0.0019179318,0.00008058457],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005680971,0.00093771523,0.000032124604,0.026015425,0.0009738605,0.00016320369,0.000063520325,2.890908e-8,0.00026321123,0.012797576,0.0004994517,0.95819706],"study_design_scores_gemma":[0.0006080724,0.0007130282,0.000029418537,0.007167243,0.0028095287,0.00006866934,6.558896e-7,0.000004320258,0.00013830201,0.00023057577,0.9878895,0.00034064183],"about_ca_topic_score_codex":0.0000147835135,"about_ca_topic_score_gemma":0.0000021170763,"teacher_disagreement_score":0.9873901,"about_ca_system_score_codex":0.00009826946,"about_ca_system_score_gemma":0.0007874173,"threshold_uncertainty_score":0.9997978},"labels":[],"label_agreement":null},{"id":"W1998319919","doi":"10.1038/cr.2013.11","title":"Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion","year":2013,"lang":"en","type":"article","venue":"Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":396,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Tokyo Medical and Dental University","keywords":"Autophagy; TFEB; Lysosome; mTORC1; Cell biology; Mechanistic target of rapamycin; Autophagosome; Biology; PI3K/AKT/mTOR pathway; ATG16L1; mTORC2; Biochemistry; Signal transduction","score_opus":0.03290305333771288,"score_gpt":0.33852927809789257,"score_spread":0.3056262247601797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998319919","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956062,0.00096734415,0.00009669453,0.00036764433,0.000052536547,0.00082878186,0.0000028424213,0.000013814885,0.0020641596],"genre_scores_gemma":[0.9989129,0.0002188958,0.000035843004,0.000070446666,0.00008622294,0.00006483652,0.0000242514,0.00001593843,0.00057067105],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981609,0.00030728584,0.0003093143,0.00023292494,0.0007066033,0.00028296083],"domain_scores_gemma":[0.9987347,0.00036601306,0.00009424406,0.00040961543,0.00029605665,0.000099330886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00078224036,0.000113945716,0.0002440065,0.0002766299,0.00008704755,0.000014915459,0.00013866206,0.00014015859,0.0007350279],"category_scores_gemma":[0.000060998307,0.00007339033,0.000060656428,0.00045219544,0.00023170687,0.0001841251,0.00007294115,0.00035779554,0.000025484807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048362406,0.000790057,0.008518127,0.0002813196,0.00002198038,0.000007841241,0.0010766448,0.000006390366,0.9675514,0.00031038956,0.0006556977,0.020296525],"study_design_scores_gemma":[0.0016086644,0.0007007442,0.4725765,0.00012659826,0.00001773233,0.0000045652127,0.0007413622,0.0013233406,0.5201815,0.0023663675,0.00029142463,0.000061261635],"about_ca_topic_score_codex":0.0002682744,"about_ca_topic_score_gemma":0.0000018923723,"teacher_disagreement_score":0.46405837,"about_ca_system_score_codex":0.00004026447,"about_ca_system_score_gemma":0.0001335259,"threshold_uncertainty_score":0.804804},"labels":[],"label_agreement":null},{"id":"W1998943082","doi":"10.1016/j.ceb.2009.12.001","title":"Autophagy regulation by p53","year":2010,"lang":"en","type":"review","venue":"Current Opinion in Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":494,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer","keywords":"Autophagy; Biology; Cell biology; Transcription factor; Regulator; Suppressor; Cytoplasm; Subcellular localization; BAG3; Mitochondrion; Programmed cell death; Dual role; Cell cycle; Cell; Gene; Genetics; Apoptosis","score_opus":0.08088662767184505,"score_gpt":0.42408726670557895,"score_spread":0.3432006390337339,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998943082","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000036852092,0.9884102,0.000048637296,0.00002269939,0.009537155,0.00089948927,0.00011230746,0.0000665816,0.00086611917],"genre_scores_gemma":[0.00003129383,0.9923536,0.000036263093,0.000023811443,0.0011606335,0.00016983584,0.005825032,0.000045481767,0.00035402903],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99809575,0.00019524289,0.00069881685,0.0005645367,0.00010478435,0.000340887],"domain_scores_gemma":[0.9988273,0.0001272451,0.00034849034,0.0005116352,0.000038769183,0.00014655665],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018906752,0.00039696012,0.0013306611,0.00027884683,0.00003756058,0.000008862826,0.00020359515,0.00086724793,0.0006879877],"category_scores_gemma":[0.000032716016,0.00030881685,0.00037001324,0.0002523665,0.00012063016,0.000028652787,0.000058152786,0.0009498766,0.00035559287],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001276359,0.00025715484,0.00002218142,0.008487374,0.000022273089,7.765936e-7,0.0000118941,3.543307e-8,0.000043328102,0.0003113563,0.00814503,0.9826858],"study_design_scores_gemma":[0.000663923,0.000114972754,0.000030521376,0.004151922,0.00010632131,0.000011752199,0.0000011518777,0.00000994585,0.0000496567,0.00024934398,0.99435294,0.0002575785],"about_ca_topic_score_codex":0.0000039781635,"about_ca_topic_score_gemma":1.8727104e-7,"teacher_disagreement_score":0.9862079,"about_ca_system_score_codex":0.00009748789,"about_ca_system_score_gemma":0.00032244998,"threshold_uncertainty_score":0.9999364},"labels":[],"label_agreement":null},{"id":"W1999211990","doi":"10.1038/ncb2757","title":"ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase","year":2013,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1534,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Cancer Institute; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research","keywords":"Autophagy; ULK1; Cell biology; Autophagy-related protein 13; Kinase; Phosphorylation; PI3K/AKT/mTOR pathway; Protein kinase A; Biology; Biochemistry; Signal transduction; Protein phosphorylation; AMPK; Apoptosis","score_opus":0.005480363798036296,"score_gpt":0.26160940128202886,"score_spread":0.25612903748399257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999211990","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9797372,0.013727503,0.000013250642,0.0006181822,0.0003373399,0.00033736214,0.000012851936,0.00009974878,0.0051165395],"genre_scores_gemma":[0.994073,0.00031450964,0.0006075682,0.003502404,0.0004062279,0.000033421045,0.000093195194,0.0000273436,0.000942327],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886,0.000065711756,0.00023622971,0.00039809462,0.00009099767,0.00034898098],"domain_scores_gemma":[0.9991539,0.00021647927,0.00013638675,0.00023128933,0.00007867719,0.00018322855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000121032775,0.00021720263,0.00032558254,0.00006788577,0.00012355334,0.00002044763,0.000102464604,0.0007233936,0.00065392925],"category_scores_gemma":[0.00013347542,0.0001673883,0.00007197117,0.00013098458,0.00011890693,0.00008470229,0.000059096557,0.00085199374,0.00006063977],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055549506,0.0001135466,0.0031315777,0.00004675262,0.000051704297,0.000010885653,0.00018270934,1.894417e-7,0.9252452,0.0001510371,0.003441108,0.0675697],"study_design_scores_gemma":[0.0016375077,0.00037243174,0.01124955,0.00004879613,0.00003805434,0.000013903496,0.0001830989,0.00013548482,0.9619274,0.0006190558,0.023529144,0.00024556334],"about_ca_topic_score_codex":0.00006597583,"about_ca_topic_score_gemma":7.350053e-7,"teacher_disagreement_score":0.06732415,"about_ca_system_score_codex":0.000029537801,"about_ca_system_score_gemma":0.000051478804,"threshold_uncertainty_score":0.7160067},"labels":[],"label_agreement":null},{"id":"W1999694989","doi":"10.1073/pnas.1300064110","title":"Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation","year":2013,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; Scaffold protein; Cytoplasm; Phosphorylation; Chemistry; Biology; BAG3; Biochemistry; Signal transduction; Apoptosis","score_opus":0.030449379231922015,"score_gpt":0.28230007130438217,"score_spread":0.25185069207246014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999694989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9862387,0.00016818615,0.0000015976296,0.010084646,0.000019716972,0.0006685162,0.0000071292743,0.000018529705,0.002792937],"genre_scores_gemma":[0.99878687,0.000020526877,0.0002484007,0.00041127802,0.00008196677,0.000034731824,8.623111e-7,0.000008326347,0.00040704274],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99779445,0.000016733333,0.00038562092,0.00021928795,0.0014223234,0.00016160733],"domain_scores_gemma":[0.9982836,0.00012379402,0.00081393804,0.000030547184,0.00071124354,0.000036864836],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00069860945,0.0001316529,0.00020246631,0.00012393555,0.00039071907,0.000028019327,0.00056420994,0.00008628387,0.00008808384],"category_scores_gemma":[0.00019891717,0.00006207893,0.00011450995,0.0010097349,0.0010842027,0.00054238364,0.000095847565,0.0001504892,0.000002346611],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012827915,0.00015344037,0.0425253,0.00020586797,0.00010304918,1.3195761e-8,0.0009076593,0.00029085772,0.91739345,0.036055874,0.0015030083,0.000733178],"study_design_scores_gemma":[0.00038398878,0.000051464627,0.58157843,0.00012690008,0.000035286335,0.0000069166517,0.00019890368,0.0017899952,0.40740114,0.0083436575,0.000035862147,0.000047412126],"about_ca_topic_score_codex":0.000023939521,"about_ca_topic_score_gemma":2.196618e-7,"teacher_disagreement_score":0.53905314,"about_ca_system_score_codex":0.00006134885,"about_ca_system_score_gemma":0.000068932,"threshold_uncertainty_score":0.39947897},"labels":[],"label_agreement":null},{"id":"W2000009880","doi":"10.1038/cdd.2014.151","title":"Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity","year":2014,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":121,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Institute on Aging; Medical Research Council; Cambridge Institute for Medical Research, University of Cambridge; Tau Consortium; National Institute for Health and Care Research; University of Cambridge; Wellcome Trust","keywords":"Calpain; Autophagy; Calpastatin; Huntingtin; Cell biology; Downregulation and upregulation; Gene knockdown; Biology; Programmed cell death; Neurodegeneration; BAG3; Phenotype; Disease; Apoptosis; Mutant; Medicine; Gene; Biochemistry; Enzyme; Internal medicine","score_opus":0.01061280776374971,"score_gpt":0.22218477648734025,"score_spread":0.21157196872359055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000009880","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9824624,0.00031623387,0.0148831215,0.00014536669,0.0001626382,0.00043503448,0.0000075412963,0.0001273975,0.0014602601],"genre_scores_gemma":[0.99823713,0.00016651004,0.0000878335,0.00044099792,0.00028581018,0.000048193255,0.0002369911,0.000018154287,0.0004783721],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990455,0.00007566849,0.0002108486,0.0002610083,0.00021871943,0.00018829046],"domain_scores_gemma":[0.999488,0.000027861122,0.00009795888,0.00015896621,0.000050857558,0.00017638651],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014402672,0.00015882961,0.00019348259,0.00010909507,0.00012633119,0.0000339691,0.000024259956,0.00012497308,0.000076416516],"category_scores_gemma":[0.00004787503,0.0001340979,0.00006209312,0.00007301353,0.00002438545,0.00010329364,0.000018667508,0.00012240285,0.000025303612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032089977,0.0007306243,0.012765388,0.00033103552,0.000053165244,0.000011939837,0.0003428084,0.000012191546,0.9354621,0.0009878156,0.00010094756,0.04888109],"study_design_scores_gemma":[0.0028196268,0.0003631955,0.302559,0.000061083374,0.000105095176,0.0000073157985,0.000031734642,0.015051981,0.67707044,0.0015864115,0.00015733772,0.00018679512],"about_ca_topic_score_codex":0.000022504715,"about_ca_topic_score_gemma":0.0000068475265,"teacher_disagreement_score":0.2897936,"about_ca_system_score_codex":0.000050749044,"about_ca_system_score_gemma":0.000023763025,"threshold_uncertainty_score":0.5468354},"labels":[],"label_agreement":null},{"id":"W2000219934","doi":"10.1016/j.taap.2011.12.004","title":"Cation trapping by cellular acidic compartments: Beyond the concept of lysosomotropic drugs","year":2011,"lang":"en","type":"review","venue":"Toxicology and Applied Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":126,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Vacuole; Bafilomycin; Endosome; Cell biology; Lysosome; Autophagy; Golgi apparatus; Organelle; Phospholipidosis; Endocytosis; V-ATPase; Nocodazole; Vacuolization; Chemistry; Biophysics; Biochemistry; Autophagosome; Cytoplasm; ATPase; Biology; Intracellular; Cell; Cytoskeleton; Membrane; Endoplasmic reticulum; Enzyme","score_opus":0.032257723454107885,"score_gpt":0.3360520532622827,"score_spread":0.30379432980817483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000219934","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0040888577,0.99111634,0.00005722369,0.00016156708,0.0003912473,0.0018439434,0.00006589898,0.000040802293,0.0022340876],"genre_scores_gemma":[0.045777116,0.9509011,0.000025407446,0.0018619285,0.0002098079,0.0005042165,0.00030305202,0.000039759456,0.000377643],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99825835,0.00026838554,0.0006126353,0.00041755498,0.00009571715,0.0003473535],"domain_scores_gemma":[0.9988394,0.00024235989,0.0004873391,0.00025954813,0.000028718478,0.00014264983],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00017733967,0.0003843606,0.0016235092,0.000109473825,0.00014556774,0.000003879561,0.00023539765,0.00050318084,0.0019055693],"category_scores_gemma":[0.0000028099937,0.0002650103,0.00021275626,0.00016544804,0.0010548683,0.000021597996,0.000068017915,0.0005565308,0.000045094486],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029402616,0.0010448084,0.0000028345573,0.004115209,0.0032184208,0.000023851619,0.0010477075,7.9779824e-7,0.0062041148,0.00998152,0.019854665,0.95421207],"study_design_scores_gemma":[0.00240894,0.00030159537,0.0000060387865,0.00019209326,0.005121982,0.00003430529,0.00008058779,0.0000057342622,0.018451497,0.00037262778,0.9727728,0.00025179324],"about_ca_topic_score_codex":0.000003303709,"about_ca_topic_score_gemma":2.0179193e-7,"teacher_disagreement_score":0.95396024,"about_ca_system_score_codex":0.000051802203,"about_ca_system_score_gemma":0.0002274834,"threshold_uncertainty_score":0.9999802},"labels":[],"label_agreement":null},{"id":"W2000413234","doi":"10.1371/journal.ppat.1003328","title":"DRAM Triggers Lysosomal Membrane Permeabilization and Cell Death in CD4+ T Cells Infected with HIV","year":2013,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"Fundação para a Ciência e a Tecnologia; Ministério da Ciência, Tecnologia e Ensino Superior; Centre National de la Recherche Scientifique","keywords":"Autophagy; Cell biology; Programmed cell death; ATG5; Biology; Small interfering RNA; Apoptosis; Cell culture; Transfection; Genetics","score_opus":0.009783042728341176,"score_gpt":0.21353849243789666,"score_spread":0.20375544970955548,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000413234","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99661547,0.00017819546,0.00003710176,0.000114128336,0.00002317448,0.000791885,0.000016208725,0.00008545073,0.0021383984],"genre_scores_gemma":[0.9982941,0.00016983144,0.0005491349,0.00029082331,0.000057793106,0.00007868521,0.000060499766,0.000037183036,0.0004619636],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989989,0.000056286954,0.00019809284,0.00028498407,0.0002035595,0.00025817376],"domain_scores_gemma":[0.99937326,0.00005357849,0.00005892829,0.00024025819,0.00008637896,0.00018762179],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000049066726,0.00017807027,0.00027477831,0.00013239778,0.000047142406,0.000023104014,0.00004551041,0.00009864574,0.0005320301],"category_scores_gemma":[0.000021034537,0.0001358858,0.00004231081,0.00022442683,0.000055381242,0.000115668176,0.000015524798,0.00012439674,0.000098172124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015119524,0.00071214396,0.19911689,0.00017575095,0.00005353508,0.00011791094,0.00083543855,0.000039432693,0.7982858,0.000032000946,0.0000486397,0.00043126708],"study_design_scores_gemma":[0.0067206863,0.00070615666,0.45164904,0.00019619009,0.00030934592,0.00003254591,0.0002618713,0.0075974884,0.5318652,0.00011974919,0.00014175192,0.000400004],"about_ca_topic_score_codex":0.000023765358,"about_ca_topic_score_gemma":0.0000050882013,"teacher_disagreement_score":0.26642063,"about_ca_system_score_codex":0.000042492036,"about_ca_system_score_gemma":0.00008142661,"threshold_uncertainty_score":0.5825357},"labels":[],"label_agreement":null},{"id":"W2000532298","doi":"10.1016/j.bbrc.2013.10.098","title":"The interplay between epigenetic silencing, oncogenic KRas and HIF-1 regulatory pathways in control of BNIP3 expression in human colorectal cancer cells","year":2013,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Children's Hospital; McGill University","funders":"","keywords":"KRAS; Autophagy; Gene silencing; Biology; Cancer research; Epigenetics; Cancer cell; Cell biology; Colorectal cancer; Cancer; Genetics; Gene; Apoptosis","score_opus":0.039344307414104045,"score_gpt":0.37670627318193606,"score_spread":0.337361965767832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000532298","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929361,0.0054009887,0.000003328746,0.0009826113,0.0000060642906,0.0005497707,0.000021401165,0.000007761942,0.000091973816],"genre_scores_gemma":[0.997265,0.0023335258,0.00005050605,0.00002982924,0.00004480129,0.00022689272,0.000013755482,0.000009324766,0.000026392834],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987329,0.0002524588,0.0002895384,0.00019498735,0.00026204393,0.00026805233],"domain_scores_gemma":[0.9981767,0.0009523214,0.00004963567,0.0005218534,0.00012203364,0.0001774857],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034594734,0.00009755668,0.00023882304,0.000082575454,0.00017155461,0.000020116946,0.0003306024,0.000102576174,0.000020566267],"category_scores_gemma":[0.00011388111,0.00006451213,0.00004882577,0.00024780983,0.0011363844,0.00003834806,0.00026234853,0.00046518137,0.0000038636867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000062986976,0.00024877602,0.008028608,0.00002927227,0.00001924455,7.335511e-7,0.00022342944,7.9873004e-8,0.98687536,0.0002595454,0.0001184801,0.004133465],"study_design_scores_gemma":[0.00081325567,0.00016686546,0.23545934,0.00020324608,0.000010993116,3.3155138e-7,0.00016319983,0.0002809522,0.7610802,0.001700161,0.000059926777,0.00006149501],"about_ca_topic_score_codex":0.00046446853,"about_ca_topic_score_gemma":0.000030416562,"teacher_disagreement_score":0.22743075,"about_ca_system_score_codex":0.00007078877,"about_ca_system_score_gemma":0.00009693189,"threshold_uncertainty_score":0.41870558},"labels":[],"label_agreement":null},{"id":"W2000933385","doi":"10.1016/j.bbrc.2009.08.047","title":"Aggresome-like structure induced by isothiocyanates is novel proteasome-dependent degradation machinery","year":2009,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; University of California, Santa Barbara; University of Alabama; Georgetown University; Université Laval","keywords":"Aggresome; Proteasome; Cell biology; Dynein; Ubiquitin; Microtubule; Chemistry; Autophagy; Protein degradation; Biology; Biochemistry","score_opus":0.05810656237611549,"score_gpt":0.37498482079199447,"score_spread":0.31687825841587897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000933385","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97695935,0.0026658678,0.000034667664,0.0191613,0.000013033643,0.00060414633,0.00015652918,0.000067217276,0.00033788418],"genre_scores_gemma":[0.9960785,0.0009700103,0.00070703676,0.0013396798,0.000096583586,0.000046279478,0.00037709746,0.000015543092,0.0003692782],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983231,0.0000992075,0.00023225295,0.00035462668,0.00063342805,0.0003574052],"domain_scores_gemma":[0.9980734,0.00017883397,0.000053799777,0.0010727136,0.00025548672,0.00036576236],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018022666,0.00017606512,0.00023476186,0.000110541325,0.0003335268,0.000068064015,0.0004914207,0.00018783683,0.00006388503],"category_scores_gemma":[0.00018393254,0.00013432378,0.00008535277,0.00046809722,0.00037842098,0.00009474847,0.00019472551,0.0008422024,0.00002095109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013475091,0.0010077365,0.000088466535,0.00002240249,0.000046179262,0.0000010246953,0.00007185232,1.1536326e-8,0.98307216,0.0015963794,0.004218103,0.009740953],"study_design_scores_gemma":[0.0017514662,0.0006619271,0.011894834,0.00014927953,0.000059186823,0.000012970618,0.000105900464,0.0010563155,0.9717655,0.005995234,0.0062435553,0.00030380936],"about_ca_topic_score_codex":0.00007074452,"about_ca_topic_score_gemma":0.000001224038,"teacher_disagreement_score":0.019119138,"about_ca_system_score_codex":0.000072884235,"about_ca_system_score_gemma":0.000111338384,"threshold_uncertainty_score":0.5477565},"labels":[],"label_agreement":null},{"id":"W2001034963","doi":"10.4161/auto.7.5.15098","title":"MCL-1 regulates the balance between autophagy and apoptosis","year":2011,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Heart and Stroke Foundation of Canada","keywords":"Autophagy; Biology; Cell biology; Apoptosis; Balance (ability); Genetics; Neuroscience","score_opus":0.03081748056547791,"score_gpt":0.26080433784255463,"score_spread":0.22998685727707674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001034963","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98617387,0.0028589468,0.000071398055,0.0006964616,0.00019218825,0.00038222125,0.000014580478,0.00023004707,0.009380277],"genre_scores_gemma":[0.9944502,0.00022304227,0.00058091606,0.0015241458,0.00031834346,0.000044936147,0.000016565416,0.0000422523,0.002799575],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9985972,0.000067094006,0.0003015925,0.0003811711,0.00024928004,0.00040367563],"domain_scores_gemma":[0.99887,0.00009982046,0.000101326375,0.00064045493,0.00006078187,0.00022757942],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021821946,0.00024849988,0.00038588262,0.00007426631,0.00020097272,0.00002551224,0.00021554866,0.0001428181,0.0008132151],"category_scores_gemma":[0.000045505094,0.00016502732,0.00013029746,0.00021015335,0.00028673932,0.00012567732,0.00008352216,0.00022523147,0.00016121424],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018831292,0.0021962335,0.38286987,0.00090894103,0.0053422647,0.0006022474,0.02663848,0.0000035130815,0.08943583,0.08608997,0.028909668,0.37511986],"study_design_scores_gemma":[0.0013577003,0.00027206683,0.6926405,0.000056758683,0.00026117268,0.000051262912,0.00012266968,0.00010426882,0.29160008,0.006382603,0.0069191284,0.00023179971],"about_ca_topic_score_codex":0.000073776566,"about_ca_topic_score_gemma":0.0000010589617,"teacher_disagreement_score":0.37488806,"about_ca_system_score_codex":0.000028165834,"about_ca_system_score_gemma":0.00006924857,"threshold_uncertainty_score":0.8904135},"labels":[],"label_agreement":null},{"id":"W2002531872","doi":"10.1016/j.bbamcr.2010.03.011","title":"AKT loss in human epithelial cells treated with severe hypoxia","year":2010,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"Canadian Institutes of Health Research; Calgary Laboratory Services","keywords":"Protein kinase B; PI3K/AKT/mTOR pathway; AKT2; AKT1; Autophagy; Hypoxia (environmental); Cell biology; Biology; Cancer research; Calpain; Chemistry; Apoptosis; Phosphorylation; Signal transduction; Biochemistry","score_opus":0.01861815118768939,"score_gpt":0.31803650776744063,"score_spread":0.29941835657975124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2002531872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98858696,0.000057511985,0.000008024422,0.0011179369,0.0000582884,0.0011289165,0.00006486843,0.000102881335,0.00887458],"genre_scores_gemma":[0.9971133,0.00007250133,0.00028364378,0.000378414,0.00020731508,0.00010033094,0.0001495934,0.0001429941,0.0015519228],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9959672,0.0003856536,0.00039488712,0.0009352566,0.0012542157,0.0010627641],"domain_scores_gemma":[0.99761933,0.00013286408,0.00010871234,0.0012994764,0.0003006057,0.00053902686],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005595076,0.000454766,0.00055013166,0.00053715357,0.00021833685,0.000107194915,0.00058428466,0.0003453931,0.00028284956],"category_scores_gemma":[0.000033093176,0.0003683523,0.00023821977,0.0011039568,0.0006597604,0.00011754347,0.00019000408,0.0017467185,0.00023290185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010475995,0.001504625,0.00006053982,0.00010668539,0.00012466437,0.001196554,0.00025361325,0.000001996257,0.9947258,0.00034838804,0.0003569943,0.00027250694],"study_design_scores_gemma":[0.003790839,0.0011088388,0.0056002303,0.000086411324,0.000070009904,0.000027445883,0.00006546471,0.000049716567,0.98768085,0.00048717242,0.0006134857,0.00041955427],"about_ca_topic_score_codex":0.00028581527,"about_ca_topic_score_gemma":0.000027092625,"teacher_disagreement_score":0.008526293,"about_ca_system_score_codex":0.000095398216,"about_ca_system_score_gemma":0.00049572805,"threshold_uncertainty_score":0.99987686},"labels":[],"label_agreement":null},{"id":"W2002686921","doi":"10.1097/aln.0000000000000656","title":"Relationship between Autophagy and Ventilator-induced Diaphragmatic Dysfunction","year":2015,"lang":"en","type":"article","venue":"Anesthesiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research; McGill University Health Centre; McGill University","keywords":"Autophagy; Autophagosome; Medicine; Diaphragm (acoustics); Diaphragmatic breathing; Internal medicine; Diaphragm muscle; Endocrinology; Apoptosis; Pathology; Respiratory system; Biology; Biochemistry","score_opus":0.08532317430617781,"score_gpt":0.31850337497424885,"score_spread":0.23318020066807105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2002686921","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981445,0.00074584474,0.000023560513,0.00024887716,0.000094034825,0.00018548669,7.492386e-7,0.000094990224,0.00046196269],"genre_scores_gemma":[0.9987668,0.000007744858,0.00011022741,0.00057722034,0.00020470665,0.000019403888,0.00003324729,0.00001667928,0.00026397896],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9992609,0.00009533355,0.00018547919,0.00019039729,0.00010099425,0.00016688807],"domain_scores_gemma":[0.9992797,0.00018822262,0.00006316543,0.00021710282,0.000042083313,0.00020977395],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021358396,0.00010831862,0.00025152782,0.00008987332,0.000058588364,0.000006605639,0.000041096453,0.00016275153,0.000034868866],"category_scores_gemma":[0.00018616546,0.0000908393,0.000044148423,0.00010357312,0.00006391514,0.00006300178,0.00001416809,0.00013164213,0.00016465849],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001022132,0.00003889449,0.9950785,0.000025351375,0.000028489785,0.00007271153,0.00024756428,5.291392e-7,0.00032422983,0.0013360141,0.0003503535,0.0023951351],"study_design_scores_gemma":[0.0010523729,0.0005367737,0.98735124,0.000015065276,0.000103197155,0.00012649239,0.000071418646,0.000020456124,0.0011241136,0.008418189,0.0010960117,0.00008467781],"about_ca_topic_score_codex":0.000017823646,"about_ca_topic_score_gemma":7.208173e-7,"teacher_disagreement_score":0.0077272817,"about_ca_system_score_codex":0.000028846862,"about_ca_system_score_gemma":0.00008617669,"threshold_uncertainty_score":0.3704319},"labels":[],"label_agreement":null},{"id":"W2002712538","doi":"10.4161/sgtp.19422","title":"Rags connect mTOR and autophagy","year":2012,"lang":"en","type":"article","venue":"Small GTPases","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"Cancer Research UK","keywords":"Autophagy; PI3K/AKT/mTOR pathway; Cell biology; Biology; RPTOR; Lysosome; Catabolism; Regulator; mTORC1; Mechanistic target of rapamycin; Compartment (ship); Anabolism; Amino acid; mTORC2; ULK1; Signal transduction; Biochemistry; Kinase; Protein kinase A; Metabolism; Apoptosis; Gene; Enzyme","score_opus":0.027504043844108518,"score_gpt":0.27522328453047235,"score_spread":0.24771924068636383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2002712538","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98663676,0.00920606,0.00007984376,0.0003004929,0.00021603277,0.00017607538,0.000009140654,0.000113034184,0.0032625725],"genre_scores_gemma":[0.9952624,0.00012712266,0.00027490774,0.0017817678,0.0004646371,0.000018775481,0.000014346816,0.000019746862,0.0020363112],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9993793,0.000023584686,0.00011293282,0.00013000453,0.000091053946,0.00026317357],"domain_scores_gemma":[0.99941266,0.00007608733,0.000031668864,0.00018947702,0.000025227522,0.0002648622],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009082857,0.00011501472,0.00018355956,0.00004735065,0.000055494314,0.000010154637,0.00003753044,0.00005681456,0.00074466807],"category_scores_gemma":[0.00006681653,0.000091540365,0.000058719732,0.00005997521,0.000062315994,0.00007056313,0.000024023617,0.000072675924,0.00011836182],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022986524,0.0037595886,0.6546381,0.000983263,0.001476032,0.00081099814,0.005232904,0.0000022148124,0.1209058,0.04776019,0.028726434,0.13340579],"study_design_scores_gemma":[0.0044672657,0.00050080515,0.7464004,0.00013208279,0.0003717752,0.0003195185,0.00036203628,0.000074086995,0.1551984,0.00055269164,0.09115969,0.00046125325],"about_ca_topic_score_codex":0.000019297593,"about_ca_topic_score_gemma":0.0000013351447,"teacher_disagreement_score":0.13294454,"about_ca_system_score_codex":0.000015251366,"about_ca_system_score_gemma":0.000036022102,"threshold_uncertainty_score":0.8153593},"labels":[],"label_agreement":null},{"id":"W2003974486","doi":"10.4161/auto.9125","title":"NADPH oxidases contribute to autophagy regulation","year":2009,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Autophagy; Phagosome; NADPH oxidase; Biology; Cell biology; Reactive oxygen species; Phagocytosis; Signal transduction; Receptor; Biochemistry; Apoptosis","score_opus":0.01079055363699963,"score_gpt":0.29154949810402475,"score_spread":0.2807589444670251,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003974486","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9814582,0.0015393269,0.0027372984,0.0044781067,0.00035435634,0.000829148,0.000026841948,0.0005813008,0.007995449],"genre_scores_gemma":[0.9778027,0.000039480517,0.0013598215,0.013307963,0.00046604377,0.000030624728,0.00008489246,0.000030881543,0.0068776086],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99819463,0.000050022572,0.00039147845,0.000444593,0.0004156043,0.000503666],"domain_scores_gemma":[0.99859875,0.0000612442,0.000093401235,0.0006183595,0.00015804303,0.00047019718],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00017855695,0.00026969652,0.00044897659,0.00019822101,0.00013968414,0.000034039775,0.00014246911,0.00015524273,0.0011981456],"category_scores_gemma":[0.00014434701,0.00024581005,0.00019260676,0.0004163082,0.000042350086,0.0001582879,0.000026220427,0.00015832938,0.0007951399],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019817962,0.0017294199,0.000849215,0.00008280635,0.00040463082,0.0012877884,0.0009258525,0.0001981761,0.61433434,0.0710635,0.051610988,0.25553146],"study_design_scores_gemma":[0.003177298,0.0011375521,0.5691386,0.00010910158,0.00013001486,0.00011941325,0.000021440537,0.0005124621,0.34970224,0.005299737,0.07029012,0.0003619995],"about_ca_topic_score_codex":0.000021337039,"about_ca_topic_score_gemma":0.000001986187,"teacher_disagreement_score":0.5682894,"about_ca_system_score_codex":0.00012517135,"about_ca_system_score_gemma":0.0001473931,"threshold_uncertainty_score":0.9999994},"labels":[],"label_agreement":null},{"id":"W2004730219","doi":"10.1038/nrneph.2014.201","title":"Mechanisms and biological functions of autophagy in diseased and ageing kidneys","year":2014,"lang":"en","type":"review","venue":"Nature Reviews Nephrology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Autophagy; Cell biology; Autophagosome; Homeostasis; Inflammation; Programmed cell death; Cytoplasm; Podocyte; Immune system; Mitochondrion; Biology; Kidney; Apoptosis; Medicine; Immunology; Biochemistry; Endocrinology","score_opus":0.030337148969231693,"score_gpt":0.3499342610051313,"score_spread":0.31959711203589963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2004730219","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016344286,0.99744755,0.00013979131,0.00011108426,0.00016568539,0.0016899479,0.000038147035,0.00003389471,0.00021044679],"genre_scores_gemma":[0.00033204362,0.9962813,0.00042015873,0.0022816705,0.0001598744,0.00020633552,0.00019624403,0.000035327987,0.00008699059],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973386,0.0007087933,0.0009130845,0.00061575446,0.00011433157,0.00030945035],"domain_scores_gemma":[0.998455,0.00031734165,0.00047017095,0.00046357382,0.00003566922,0.00025822906],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005937034,0.0004723331,0.0038911337,0.00031836066,0.000045454133,0.000006920447,0.00013087287,0.0015312046,0.00017201582],"category_scores_gemma":[0.0004181297,0.0002997398,0.00046213792,0.00033016858,0.0002145427,0.000029486264,0.00009451074,0.0012222503,0.000020508905],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053626827,0.000112703776,0.000022802249,0.019329118,0.0001883424,0.0001656471,0.000010511559,1.522454e-8,0.000033701563,0.0028009969,0.00079668534,0.97648585],"study_design_scores_gemma":[0.0007064219,0.00031169684,0.0010817338,0.0062499824,0.0012709117,0.00020194107,0.0000015830728,0.000006669993,7.8651595e-7,0.00082593295,0.98913187,0.0002104469],"about_ca_topic_score_codex":0.000003633877,"about_ca_topic_score_gemma":0.000002760355,"teacher_disagreement_score":0.9883352,"about_ca_system_score_codex":0.000036506404,"about_ca_system_score_gemma":0.00015939075,"threshold_uncertainty_score":0.99994546},"labels":[],"label_agreement":null},{"id":"W2005001992","doi":"10.1152/japplphysiol.00893.2012","title":"Role of autophagy in COPD skeletal muscle dysfunction","year":2012,"lang":"en","type":"review","venue":"Journal of Applied Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Skeletal muscle; Muscle atrophy; Lysosome; Protein degradation; Atrophy; COPD; Sarcopenia; Biology; Endocrinology; Internal medicine; Cell biology; Medicine; Biochemistry; Apoptosis","score_opus":0.02105667011513226,"score_gpt":0.303789313095207,"score_spread":0.2827326429800748,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005001992","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.013188007,0.9844,0.000003750975,0.0000043683826,0.00031302887,0.00034002188,0.000007695937,0.0000074086324,0.0017357663],"genre_scores_gemma":[0.051460367,0.94719917,0.00009931838,0.000070365066,0.001032916,0.000019465884,0.000037817925,0.000041312516,0.000039260194],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982998,0.00007909509,0.001011049,0.00015923542,0.00019419262,0.00025667355],"domain_scores_gemma":[0.9981809,0.00010747809,0.0012534247,0.0002538924,0.00007208921,0.00013216063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024250876,0.00026785707,0.0022774742,0.0003288399,0.00001632293,0.0000020919192,0.0001624293,0.0003820305,0.00041785068],"category_scores_gemma":[0.0000089799,0.00019066586,0.00060679985,0.00022090843,0.00009006919,0.000043964785,0.00003483832,0.0006537672,0.000050259237],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002518071,0.00056463515,0.000001197663,0.0038387165,0.00046867083,0.000015533305,0.00009112989,0.0000032658302,0.0073054014,0.00071019464,0.0001348411,0.9866146],"study_design_scores_gemma":[0.0015463972,0.00035300435,0.0036931753,0.0017460723,0.0014372873,0.00012369394,0.000047241734,0.0000031319316,0.00029770462,0.0013561288,0.9892177,0.00017845308],"about_ca_topic_score_codex":0.0000024201584,"about_ca_topic_score_gemma":3.5104404e-7,"teacher_disagreement_score":0.9890829,"about_ca_system_score_codex":0.00010323794,"about_ca_system_score_gemma":0.0003527467,"threshold_uncertainty_score":0.7775128},"labels":[],"label_agreement":null},{"id":"W2005229247","doi":"10.4161/auto.5.2.7391","title":"Denervation-induced oxidative stress and autophagy signaling in muscle","year":2009,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Autophagy; Denervation; Biology; Cell biology; Downregulation and upregulation; Intracellular; Skeletal muscle; Mitochondrion; Apoptosis; Oxidative stress; Homeostasis; Endocrinology; Protein degradation; Myocyte; Internal medicine; Biochemistry; Medicine","score_opus":0.019655105071785507,"score_gpt":0.291233574230872,"score_spread":0.27157846915908646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005229247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961227,0.001161267,0.00009184168,0.0005893978,0.00009357827,0.00034174905,0.0000069038506,0.00012649411,0.0014660213],"genre_scores_gemma":[0.9965712,0.00007765634,0.00056312897,0.0022150658,0.0001566521,0.000020247586,0.000033661327,0.000021523623,0.00034089803],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99864554,0.000059255177,0.00033291927,0.0003811953,0.0002439179,0.00033716034],"domain_scores_gemma":[0.9992973,0.00008347801,0.000091298345,0.00028698117,0.00006241846,0.00017851767],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015600781,0.00021357361,0.0003492608,0.00019627564,0.00008232641,0.00003120207,0.000096122945,0.00013740723,0.0002289028],"category_scores_gemma":[0.00006546865,0.00019996986,0.0000708013,0.00029701166,0.000043485357,0.00020608658,0.000022372162,0.00021711671,0.000029099363],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029566424,0.0011352333,0.007292719,0.00009673453,0.00013606706,0.0010092184,0.0027195748,0.000093879156,0.83684915,0.009595815,0.00014795546,0.14062801],"study_design_scores_gemma":[0.002382297,0.00038467997,0.60376495,0.00015440836,0.000043467997,0.000017278518,0.00017111472,0.00092424155,0.38880035,0.0029084913,0.00023620138,0.00021251028],"about_ca_topic_score_codex":0.000070208946,"about_ca_topic_score_gemma":0.000011093442,"teacher_disagreement_score":0.59647226,"about_ca_system_score_codex":0.000070745686,"about_ca_system_score_gemma":0.00011252703,"threshold_uncertainty_score":0.8154534},"labels":[],"label_agreement":null},{"id":"W2005646573","doi":"10.4161/auto.26534","title":"Hypoxia-induced <i>MIR155</i> is a potent autophagy inducer by targeting multiple players in the MTOR pathway","year":2013,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":192,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Autophagy; PI3K/AKT/mTOR pathway; Biology; RHEB; Cell biology; microRNA; Downregulation and upregulation; Signal transduction; Inducer; Cancer research; mTORC1; Gene; Apoptosis; Biochemistry","score_opus":0.01507040210420321,"score_gpt":0.24689093353423966,"score_spread":0.23182053143003645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005646573","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99008137,0.0022766872,0.000053528653,0.0025458958,0.00043393395,0.0015807488,0.000041589985,0.00021106252,0.0027751904],"genre_scores_gemma":[0.9787818,0.0000852999,0.00030899703,0.018117364,0.00035018538,0.00048722577,0.00008970296,0.00008941245,0.0016899764],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99669147,0.00021558571,0.00071705587,0.00071075285,0.00073812687,0.0009270084],"domain_scores_gemma":[0.9981992,0.00028847053,0.00021644915,0.0008408653,0.00012489679,0.00033009893],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00047313713,0.0004984676,0.00059525133,0.00018086872,0.00022690359,0.00010719851,0.00050066225,0.00033435115,0.0015706221],"category_scores_gemma":[0.00018727273,0.00035428308,0.00029944206,0.0005237784,0.00010218861,0.00033336965,0.00009296516,0.00070670765,0.0010491704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023534875,0.0018301876,0.0032229535,0.00011037885,0.0003374684,0.00055626885,0.0075776945,0.000009090782,0.84024537,0.00041871608,0.09853476,0.046921752],"study_design_scores_gemma":[0.011029315,0.0009448915,0.1400084,0.00020460328,0.00015717014,0.00016036343,0.0024060607,0.00493266,0.7780039,0.0012061793,0.059741378,0.0012050965],"about_ca_topic_score_codex":0.0009811725,"about_ca_topic_score_gemma":0.000009110982,"teacher_disagreement_score":0.13678545,"about_ca_system_score_codex":0.00016077384,"about_ca_system_score_gemma":0.00023637128,"threshold_uncertainty_score":0.9998909},"labels":[],"label_agreement":null},{"id":"W2006465145","doi":"10.1158/1538-7445.fbcr13-b11","title":"Abstract B11: The early autophagy inhibitor verteporfin moderately enhances the antitumor activity of gemcitabine in a pancreatic ductal adenocarcinoma model","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency; Centre for Drug Research and Development; University of British Columbia","funders":"","keywords":"Verteporfin; Autophagy; Gemcitabine; Pancreatic cancer; Cancer research; Medicine; Oncology; Cancer; Apoptosis; Internal medicine; Chemistry; Surgery","score_opus":0.0684090330884039,"score_gpt":0.37251532145104344,"score_spread":0.30410628836263953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006465145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990875,0.0047150766,0.00002824424,0.002202591,0.00008183914,0.001329627,0.000020519714,0.000023834924,0.0007232898],"genre_scores_gemma":[0.99738747,0.0006506435,0.000020164602,0.00013012715,0.00023622908,0.00071133435,0.0000032785467,0.00003272658,0.0008280113],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9976888,0.00018619915,0.00032978793,0.0003592716,0.0008512874,0.0005847077],"domain_scores_gemma":[0.9985917,0.00027050124,0.00009584412,0.00056431914,0.00032807828,0.00014952658],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007496238,0.00018717366,0.00037619547,0.00015866874,0.00019773324,0.0000665873,0.0003511975,0.00009665441,0.00052506843],"category_scores_gemma":[0.0001202967,0.000103717546,0.00011201045,0.00053515495,0.000550638,0.0002718071,0.00010099232,0.00079040456,0.00006211039],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014353751,0.0005465357,0.014415033,0.0002887541,0.00021846092,0.00013173057,0.0021913066,0.000299011,0.9738478,0.00043083166,0.0015568215,0.004638337],"study_design_scores_gemma":[0.0010486442,0.00017540506,0.7063504,0.00017651446,0.000025459738,0.000009205196,0.00020848105,0.010490632,0.28011522,0.0012797203,0.000015400377,0.00010493036],"about_ca_topic_score_codex":0.0061299265,"about_ca_topic_score_gemma":0.00013931718,"teacher_disagreement_score":0.69373256,"about_ca_system_score_codex":0.00016564374,"about_ca_system_score_gemma":0.000993327,"threshold_uncertainty_score":0.92666566},"labels":[],"label_agreement":null},{"id":"W2006520597","doi":"10.1126/scisignal.265pe21","title":"Parkinson’s Disease: To Live or Die by Autophagy","year":2009,"lang":"en","type":"review","venue":"Science Signaling","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Autophagy; Parkinson's disease; Disease; Biology; Medicine; Neuroscience; Cell biology; Genetics; Internal medicine; Apoptosis","score_opus":0.05016139447555769,"score_gpt":0.3804982921629737,"score_spread":0.33033689768741603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006520597","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00025350318,0.997229,0.000094873925,0.00011173089,0.0003327509,0.0012849842,0.000079646,0.00016342095,0.00045013014],"genre_scores_gemma":[0.0004357102,0.993676,0.0005165776,0.0015322354,0.00050009595,0.00012727096,0.00005836555,0.00005411507,0.0030996061],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964116,0.00007260804,0.0005784662,0.0010745476,0.0010570106,0.0008057731],"domain_scores_gemma":[0.99735945,0.00013431723,0.0002293079,0.0007545766,0.00013383293,0.0013885171],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00067435263,0.0005142932,0.0013804127,0.0004210208,0.0003615898,0.00014633493,0.00077252055,0.00014591524,0.0008692245],"category_scores_gemma":[0.00036272997,0.00034358838,0.00045467238,0.0012887635,0.00030680047,0.00018168954,0.0001092455,0.000357053,0.0006866648],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000642576,0.00013908875,0.0000016292493,0.0018696849,0.000052193805,0.00047853062,0.0001445917,0.000002108841,0.000099788944,0.000030321282,0.0018724917,0.99524534],"study_design_scores_gemma":[0.00021921589,0.00023796491,0.000022820583,0.012709461,0.00065443147,0.000025629599,0.00002928153,0.000019438658,0.00017941996,0.00008650508,0.98539245,0.00042336594],"about_ca_topic_score_codex":0.000008471558,"about_ca_topic_score_gemma":5.1122475e-7,"teacher_disagreement_score":0.99482197,"about_ca_system_score_codex":0.00036522365,"about_ca_system_score_gemma":0.0032258958,"threshold_uncertainty_score":0.9999016},"labels":[],"label_agreement":null},{"id":"W2007773423","doi":"10.1371/journal.pone.0110655","title":"Autophagy Facilitates Antibody-Enhanced Dengue Virus Infection in Human Pre-Basophil/Mast Cells","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Ministry of Science and Technology, Taiwan; National Science Council","keywords":"Dengue virus; Antibody; Biology; Virology; Autophagy; Antibody-dependent enhancement; Virus; Immunology; Apoptosis","score_opus":0.024378192660229107,"score_gpt":0.2813598987374149,"score_spread":0.2569817060771858,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007773423","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99646115,0.00029310037,0.00043193973,0.00007727669,0.000067759596,0.00051367265,0.000016904982,0.00020062382,0.0019375917],"genre_scores_gemma":[0.99786365,0.00025841806,0.0001911308,0.00031026764,0.00026525347,0.000061004237,0.00008856276,0.000034211553,0.0009274977],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99863386,0.000098858254,0.00031743536,0.0003320651,0.00031137903,0.00030639253],"domain_scores_gemma":[0.99923885,0.00007155888,0.0000835146,0.00038094842,0.00007753947,0.00014761562],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019247949,0.0001983909,0.00041215256,0.00017753764,0.00009091121,0.000019007046,0.00008169186,0.00013067912,0.0005194396],"category_scores_gemma":[0.00008105672,0.00019020798,0.00008762536,0.00020580669,0.000073260955,0.00011062695,0.000028002822,0.0002560267,0.00030982838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000108699795,0.0024577286,0.013097494,0.00024074876,0.0001797389,0.000013966532,0.00041166,0.000029551036,0.98268485,0.000103772356,0.000028299513,0.00064347376],"study_design_scores_gemma":[0.0016739294,0.00038882074,0.18916097,0.000285855,0.00011989246,0.0000010538679,0.0000076583565,0.0004637681,0.8068789,0.0007733493,0.000085458545,0.00016031375],"about_ca_topic_score_codex":0.00032939817,"about_ca_topic_score_gemma":0.00006262103,"teacher_disagreement_score":0.17606348,"about_ca_system_score_codex":0.000073681804,"about_ca_system_score_gemma":0.000036127134,"threshold_uncertainty_score":0.7756457},"labels":[],"label_agreement":null},{"id":"W2008919192","doi":"10.4161/cc.9.2.10505","title":"The EphB2 tumor suppressor induces autophagic cell death via concomitant activation of the ERK1/2 and PI3K pathways","year":2010,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; U.S. Department of Defense","keywords":"Autophagy; Biology; Suppressor; Cell biology; PI3K/AKT/mTOR pathway; Programmed cell death; Cancer research; Apoptosis; Signal transduction; Genetics; Cancer","score_opus":0.009832463068289516,"score_gpt":0.22996785430964334,"score_spread":0.2201353912413538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008919192","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930726,0.0005594454,0.00001463348,0.00030190355,0.0002637348,0.00037370608,0.000010633239,0.000030162186,0.0053731785],"genre_scores_gemma":[0.9989063,0.0000525701,0.000062334446,0.00035487316,0.00011953198,0.00001995695,0.000004277294,0.000020482723,0.00045963278],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917966,0.00005243227,0.00020048398,0.0001769147,0.00019987128,0.00019062309],"domain_scores_gemma":[0.99904966,0.00019802595,0.0001522039,0.00045116324,0.000056110974,0.00009283846],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017806352,0.00012987001,0.00017072489,0.000022690336,0.00020980445,0.000022016164,0.00017773033,0.00007564782,0.00012357534],"category_scores_gemma":[0.00004033433,0.00007049475,0.00007916374,0.0000837551,0.00016082435,0.000065954504,0.000057121302,0.00029200097,0.000015001382],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008428308,0.00015466125,0.0013746003,0.000041373543,0.000019089712,0.0000063092716,0.0004706642,0.0000016663139,0.9956822,0.00037705715,0.00019297417,0.0015951475],"study_design_scores_gemma":[0.0010799817,0.0000849505,0.06627775,0.000019983916,0.000052002848,0.000008461558,0.00013654074,0.00044241376,0.9278913,0.002108807,0.0018169284,0.00008084737],"about_ca_topic_score_codex":0.00003692595,"about_ca_topic_score_gemma":0.000003636543,"teacher_disagreement_score":0.06779084,"about_ca_system_score_codex":0.000012771756,"about_ca_system_score_gemma":0.00009265044,"threshold_uncertainty_score":0.28746924},"labels":[],"label_agreement":null},{"id":"W2009176036","doi":"10.1086/315676","title":"Mannosylated Lipoarabinomannan Antagonizes<i>Mycobacterium tuberculosis–</i>Induced Macrophage Apoptosis by Altering Ca<sup>+2</sup>‐Dependent Cell Signaling","year":2000,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":121,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"Medical Research Council; Medical Research Council Canada; Departamento Administrativo de Ciencia, Tecnología e Innovación (COLCIENCIAS)","keywords":"Lipoarabinomannan; Mycobacterium tuberculosis; Apoptosis; Macrophage; Microbiology; Signal transduction; Tuberculosis; Chemistry; Mycobacterium; Cell biology; Biology; Medicine; Biochemistry; Pathology; In vitro","score_opus":0.005949908280737647,"score_gpt":0.23139048987476554,"score_spread":0.22544058159402788,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009176036","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99398506,0.003850497,0.000063301406,0.00029699638,0.00024473658,0.00040921473,0.00010391053,0.000115891155,0.0009304116],"genre_scores_gemma":[0.9946238,0.0026981782,0.000011882391,0.0013503134,0.00070129527,0.000012723448,0.000037089594,0.000087647124,0.00047711263],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973094,0.00031731406,0.0008846718,0.00027438343,0.0006404108,0.0005738037],"domain_scores_gemma":[0.9980744,0.00015340028,0.00042109852,0.000499342,0.00025232104,0.00059943064],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000347949,0.00045309582,0.0006807671,0.00019401926,0.00037639323,0.00011318521,0.00032969678,0.00014217671,0.0030849862],"category_scores_gemma":[0.000039776805,0.00031859629,0.00050512963,0.00034832815,0.00010957391,0.00035182736,0.00004921922,0.0005537152,0.00015919792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0073577636,0.005831613,0.016262606,0.0006399025,0.0032023364,0.0010841027,0.004080981,0.015273452,0.92111826,0.0000061522105,0.010769875,0.01437296],"study_design_scores_gemma":[0.018590845,0.005589037,0.013605086,0.0011581683,0.00710929,0.003801017,0.0015806147,0.003943564,0.93908566,0.00037373742,0.003509077,0.0016538944],"about_ca_topic_score_codex":0.0001413852,"about_ca_topic_score_gemma":7.9310513e-7,"teacher_disagreement_score":0.017967412,"about_ca_system_score_codex":0.00021956988,"about_ca_system_score_gemma":0.00019729944,"threshold_uncertainty_score":0.9999266},"labels":[],"label_agreement":null},{"id":"W2009734791","doi":"10.4161/auto.21211","title":"ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy","year":2012,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":424,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Mitochondrion; Cell biology; Parkin; Autophagy; Mitochondrial ROS; Reactive oxygen species; Biology; PINK1; Biochemistry; Apoptosis","score_opus":0.019302661543294353,"score_gpt":0.2813854675212044,"score_spread":0.26208280597791006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009734791","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97982633,0.0043933797,0.0053104125,0.00030798712,0.0058170995,0.0013078165,0.00008595868,0.0005635079,0.002387479],"genre_scores_gemma":[0.98949486,0.00014707369,0.0019972634,0.001381215,0.0034725573,0.00019495256,0.0010065386,0.00012907859,0.0021764738],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964693,0.00023399151,0.00079188583,0.00064134976,0.0008698238,0.0009936094],"domain_scores_gemma":[0.99793005,0.00016335586,0.00034352648,0.0007322094,0.0001691367,0.0006617267],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020230876,0.00053881103,0.0006476351,0.00024826208,0.00030941158,0.00010744388,0.00026829718,0.00049249915,0.0011052547],"category_scores_gemma":[0.00021045575,0.00051093055,0.00030503352,0.00041634255,0.00009180367,0.00083154754,0.00008444324,0.00045345863,0.00044122158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00086682814,0.0013936978,0.003861333,0.00007098337,0.00045914305,0.00007108163,0.00063594704,0.0000061445453,0.9721098,0.0016659953,0.0073360796,0.011522985],"study_design_scores_gemma":[0.0071245735,0.00049982395,0.028711258,0.00007856424,0.0005442611,0.00014663415,0.000089231275,0.0005316101,0.94906086,0.00034007218,0.012187049,0.0006860518],"about_ca_topic_score_codex":0.00016669281,"about_ca_topic_score_gemma":0.000009207188,"teacher_disagreement_score":0.024849923,"about_ca_system_score_codex":0.00024460864,"about_ca_system_score_gemma":0.00027447357,"threshold_uncertainty_score":0.9998079},"labels":[],"label_agreement":null},{"id":"W2010758581","doi":"10.4161/auto.5.4.8061","title":"An executioner caspase regulates autophagy","year":2009,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Genome British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Cell biology; Programmed cell death; Apoptosis; Drosophila melanogaster; Genetic screen; TUNEL assay; BAG3; Caspase; RNA interference; ATG5; Signal transduction; Mutant; Gene; Genetics","score_opus":0.009643230727387667,"score_gpt":0.3043332347486891,"score_spread":0.29469000402130147,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010758581","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9878549,0.0016294674,0.00031835373,0.0011123494,0.0003097613,0.000368652,0.000011719794,0.000644507,0.007750299],"genre_scores_gemma":[0.9864974,0.00008465822,0.0010824067,0.006317809,0.0005201622,0.000019106734,0.00011005159,0.000037933583,0.005330471],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9982328,0.00006594886,0.00035472037,0.00049553986,0.00035884994,0.0004921346],"domain_scores_gemma":[0.9984102,0.000028684806,0.00009338891,0.0008819808,0.00011078126,0.00047494168],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016032708,0.00029380937,0.00040508682,0.0001690463,0.00017360633,0.00004582492,0.00019501444,0.00019433194,0.0017134559],"category_scores_gemma":[0.000032631557,0.0002560684,0.00019410285,0.0003021503,0.00009720707,0.00029279653,0.000015529342,0.00021469693,0.00037811848],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016733872,0.005580277,0.0013344064,0.000106493135,0.00043659247,0.0057323435,0.0023716069,0.00020438762,0.6757499,0.055532746,0.02109609,0.23018177],"study_design_scores_gemma":[0.0042255935,0.0021014162,0.5004626,0.000080635706,0.0002516972,0.0005856443,0.00010288291,0.0033188572,0.45901164,0.012186315,0.017054154,0.0006185683],"about_ca_topic_score_codex":0.000028945202,"about_ca_topic_score_gemma":0.0000016973437,"teacher_disagreement_score":0.4991282,"about_ca_system_score_codex":0.00006350366,"about_ca_system_score_gemma":0.00015974016,"threshold_uncertainty_score":0.99998915},"labels":[],"label_agreement":null},{"id":"W2010761086","doi":"10.4161/auto.5.2.7529","title":"Macroautophagy: The key ingredient to a healthy diet?","year":2009,"lang":"hu","type":"review","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Neurodegeneration; Cancer; Disease; Degeneration (medical); Cell biology; Neuroscience; Function (biology); Bioinformatics; Biochemistry; Internal medicine; Medicine; Pathology; Genetics","score_opus":0.04046721663649898,"score_gpt":0.36110033064865926,"score_spread":0.32063311401216027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010761086","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0020448675,0.9716462,0.00010934986,0.0059838896,0.004682482,0.006831033,0.000256345,0.0004921757,0.007953686],"genre_scores_gemma":[0.006460925,0.937753,0.0002850081,0.03667168,0.0054861642,0.0008510512,0.0003316573,0.00037024886,0.011790258],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.989362,0.0010418348,0.0027751494,0.0022658058,0.0018388283,0.0027163797],"domain_scores_gemma":[0.9918691,0.00075572426,0.0011530791,0.0038125755,0.0003662307,0.002043324],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.0016838502,0.0022120492,0.004714088,0.00067413424,0.0010495738,0.00028969525,0.0021698158,0.0011471603,0.0037816095],"category_scores_gemma":[0.00048748672,0.0014750113,0.0022913716,0.0021650693,0.00039856153,0.00018551333,0.0005478423,0.0024369264,0.013667816],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010668227,0.0012177661,0.000007081987,0.0053233984,0.0014464767,0.0015232133,0.0024783788,0.00000940885,0.000014452094,0.003254797,0.033148296,0.9505099],"study_design_scores_gemma":[0.0020764046,0.0047340165,0.00135729,0.009751058,0.0027593577,0.0002915095,0.00012658394,0.00006900999,0.000089352805,0.0004905892,0.97696286,0.0012919605],"about_ca_topic_score_codex":0.00017869052,"about_ca_topic_score_gemma":0.000019468902,"teacher_disagreement_score":0.949218,"about_ca_system_score_codex":0.001110358,"about_ca_system_score_gemma":0.0026779298,"threshold_uncertainty_score":0.9998645},"labels":[],"label_agreement":null},{"id":"W2011256652","doi":"10.4137/grsb.s13946","title":"Tetracycline Derivative Minocycline Inhibits Autophagy and Inflammation in Concanavalin-A-Activated Human Hepatoma Cells","year":2014,"lang":"en","type":"article","venue":"Gene Regulation and Systems Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Minocycline; Autophagy; Vacuole; Gene silencing; Concanavalin A; Signal transduction; Cell biology; Inflammation; STAT3; Biology; Chemistry; Cancer research; Molecular biology; Biochemistry; Immunology; Gene; Apoptosis; In vitro","score_opus":0.018497014182087088,"score_gpt":0.2900405716986565,"score_spread":0.2715435575165694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011256652","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979302,0.00048162244,0.0005576912,0.00020492362,0.00013114014,0.00046806075,0.000010283675,0.00004363998,0.00017241872],"genre_scores_gemma":[0.99893755,0.0000638431,0.00011503196,0.00011666536,0.00024216458,0.000024086616,0.00022895573,0.000014017149,0.0002577032],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987636,0.00023677593,0.00046769017,0.0002843815,0.000075884,0.00017166407],"domain_scores_gemma":[0.9993821,0.00008625902,0.00018770574,0.0001560969,0.00007907379,0.000108769476],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003087392,0.00015430934,0.00039123232,0.00017834455,0.00007377141,0.000014474368,0.000027367008,0.00020837746,0.000035594167],"category_scores_gemma":[0.000041834846,0.00013045574,0.000027883141,0.00012761515,0.00010878862,0.000060171,0.000019466279,0.000087646506,0.000005907197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009319338,0.00003128244,0.024610907,0.000069396934,0.00004126054,0.0000037919674,0.00021306827,0.000019722484,0.9671696,0.002962332,0.000021487853,0.0047639473],"study_design_scores_gemma":[0.0031077822,0.00030279183,0.35854763,0.00007048692,0.00002792598,0.000034347766,0.00005681049,0.00983376,0.6242676,0.0006019586,0.002986151,0.00016279395],"about_ca_topic_score_codex":0.00011650741,"about_ca_topic_score_gemma":0.00002897944,"teacher_disagreement_score":0.34290203,"about_ca_system_score_codex":0.000037943526,"about_ca_system_score_gemma":0.000025562618,"threshold_uncertainty_score":0.5319831},"labels":[],"label_agreement":null},{"id":"W2011618618","doi":"10.1089/ars.2010.3479","title":"Regulation of Autophagy in the Heart: “You Only Live Twice”","year":2010,"lang":"en","type":"review","venue":"Antioxidants and Redox Signaling","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Autophagy; Cell biology; Organelle; Mitochondrion; Programmed cell death; Effector; Biology; Lysosome; Mitochondrial permeability transition pore; Signal transduction; ATG16L1; Chemistry; Apoptosis; Biochemistry; Enzyme","score_opus":0.027596931923109205,"score_gpt":0.3325646688097491,"score_spread":0.3049677368866399,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011618618","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.046167534,0.9525127,0.000009094564,0.000052676685,0.00015689072,0.00071242,0.000017386154,0.000019715306,0.00035160416],"genre_scores_gemma":[0.0348989,0.9640884,0.00016448469,0.0001502078,0.00034675543,0.000017040442,0.000051516527,0.00003671935,0.0002459685],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99839187,0.0001581172,0.0006327518,0.00031608078,0.00027993327,0.00022126798],"domain_scores_gemma":[0.9989801,0.00019559068,0.000327868,0.0003713593,0.000056753815,0.00006830175],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005531177,0.00027647978,0.0011449873,0.000202471,0.00008086506,0.00002561442,0.00013671743,0.00035987337,0.0001318859],"category_scores_gemma":[0.00004333178,0.00016254549,0.0003282394,0.00026988465,0.00013187289,0.00006305348,0.000027675804,0.0005296824,0.000015178732],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006226394,0.0003123874,0.00013406576,0.008559179,0.00023433825,0.000111245354,0.0008496672,7.1951376e-7,0.0038092856,0.0010289538,0.0001402331,0.98475766],"study_design_scores_gemma":[0.0012816666,0.00040490596,0.007123652,0.03177358,0.0016648347,0.0007706835,0.00025437278,0.000049789018,0.0007175962,0.00058368535,0.954878,0.0004972471],"about_ca_topic_score_codex":0.000042398013,"about_ca_topic_score_gemma":0.0000039441697,"teacher_disagreement_score":0.98426044,"about_ca_system_score_codex":0.000014342403,"about_ca_system_score_gemma":0.00026713213,"threshold_uncertainty_score":0.6628413},"labels":[],"label_agreement":null},{"id":"W2012167979","doi":"10.4161/auto.7.3.14046","title":"The ubiquitin-binding adaptor proteins p62/SQSTM1 and NDP52 are recruited independently to bacteria-associated microdomains to target Salmonella to the autophagy pathway","year":2011,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":205,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Autophagy; Signal transducing adaptor protein; Biology; Salmonella enterica; Ubiquitin; Cell biology; Bacteria; Innate immune system; BAG3; Salmonella; Microbiology; Signal transduction; Immune system; Biochemistry; Genetics; Gene","score_opus":0.03339653462356597,"score_gpt":0.2561169185477631,"score_spread":0.22272038392419713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012167979","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98891795,0.0006909117,0.00025718706,0.0030747117,0.0007264506,0.0040576253,0.00028590224,0.00033756281,0.001651685],"genre_scores_gemma":[0.98178697,0.000057318255,0.0016586747,0.007384215,0.00045150935,0.00075887464,0.000054606116,0.00015094063,0.0076968824],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9961197,0.00035711055,0.00074165425,0.0009243136,0.0006820508,0.0011751882],"domain_scores_gemma":[0.997027,0.00023517503,0.00030434376,0.0011857386,0.00026763056,0.0009801431],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010759952,0.00059504376,0.0007170537,0.00026550094,0.00086436217,0.00018325482,0.0007248465,0.00029775975,0.00046141454],"category_scores_gemma":[0.00063449057,0.00039358606,0.00022484413,0.0008645576,0.00012136747,0.00013680794,0.0004173956,0.00049417396,0.0006044995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0060446225,0.0023791487,0.005148221,0.00018967914,0.0023421342,0.0032856439,0.038442314,0.000020757267,0.8759119,0.004165304,0.026406847,0.03566346],"study_design_scores_gemma":[0.0032447628,0.0019151614,0.32049528,0.0004623143,0.00022054093,0.00021614792,0.0019822905,0.00007786722,0.5524333,0.00061216054,0.11734243,0.0009977589],"about_ca_topic_score_codex":0.00024682062,"about_ca_topic_score_gemma":0.0002153773,"teacher_disagreement_score":0.32347858,"about_ca_system_score_codex":0.00029688978,"about_ca_system_score_gemma":0.00028494225,"threshold_uncertainty_score":0.9998516},"labels":[],"label_agreement":null},{"id":"W2012224340","doi":"10.1016/j.yexcr.2012.02.006","title":"Autophagy is a survival force via suppression of necrotic cell death","year":2012,"lang":"en","type":"review","venue":"Experimental Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biomedical Research Council; Institut National Du Cancer; National Medical Research Council; Institut National de la Santé et de la Recherche Médicale; Université Paris-Sud; Agence Nationale de la Recherche; CNIB","keywords":"Autophagy; Programmed cell death; Biology; Necroptosis; Cell biology; Apoptosis; Poly ADP ribose polymerase; Mitochondrion; Cell; Biochemistry; Polymerase; DNA","score_opus":0.204355219589962,"score_gpt":0.4809139004847986,"score_spread":0.2765586808948366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012224340","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0024586665,0.969985,0.000015547175,0.0000065478735,0.00037263133,0.0021370985,0.000052268162,0.00004660137,0.024925645],"genre_scores_gemma":[0.042676173,0.9346286,0.00019805529,0.000034141565,0.0004740511,0.0003198492,0.00023912401,0.0001865636,0.021243455],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9950753,0.0006713349,0.00078367436,0.00069880165,0.0016893657,0.0010815483],"domain_scores_gemma":[0.9973947,0.00035616293,0.00024929043,0.0011542155,0.00016171254,0.00068394496],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00087327446,0.0005708537,0.0018761822,0.00047770006,0.00019076909,0.00003229486,0.0005778978,0.000536894,0.006425774],"category_scores_gemma":[0.000014039998,0.00043731186,0.0008657956,0.0005069815,0.00025355245,0.00011294418,0.00047096712,0.0010919927,0.0009400468],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017274449,0.018541,0.000122784,0.14237632,0.001258857,0.0010369644,0.0057541947,3.435681e-7,0.18836668,0.00034793408,0.012609075,0.6278584],"study_design_scores_gemma":[0.0013802609,0.0008654217,0.000014577287,0.0033113258,0.00033538684,0.00003232555,0.00021622334,0.000019389678,0.44328174,0.000023136763,0.5501425,0.00037767287],"about_ca_topic_score_codex":0.00011737689,"about_ca_topic_score_gemma":2.1896503e-7,"teacher_disagreement_score":0.62748075,"about_ca_system_score_codex":0.00040168234,"about_ca_system_score_gemma":0.0006764194,"threshold_uncertainty_score":0.9998378},"labels":[],"label_agreement":null},{"id":"W2012576981","doi":"10.1016/j.semcancer.2015.02.007","title":"Cancer prevention and therapy through the modulation of the tumor microenvironment","year":2015,"lang":"en","type":"review","venue":"Seminars in Cancer Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":389,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; Dalhousie University","funders":"Thales Group; Ministerstvo Zdravotnictví Ceské Republiky; Ministry of Education, Culture, Sports, Science and Technology; Grantová Agentura České Republiky; Center for Hierarchical Manufacturing, National Science Foundation; University of Glasgow; Univerzita Karlova v Praze; Marie Curie; National Cancer Institute; National Institutes of Health; Cancer Research UK","keywords":"Tumor microenvironment; Angiogenesis; Cancer research; Carcinogenesis; Tumor hypoxia; Biology; Cancer; Immunology; Medicine; Internal medicine","score_opus":0.05697428158445467,"score_gpt":0.40198081012291703,"score_spread":0.34500652853846236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012576981","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.013133109,0.9847966,0.0000037505424,0.00025607826,0.0003664609,0.0012827942,0.00007537698,0.000005333895,0.000080512225],"genre_scores_gemma":[0.0019269657,0.99661297,0.000028451792,0.00029116817,0.00018332193,0.00052297325,0.00003709591,0.000023925742,0.0003731325],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998859,0.00024219057,0.0003615303,0.0002723453,0.0001017623,0.0001631626],"domain_scores_gemma":[0.99916595,0.00005314149,0.00036020955,0.00037344557,0.000021507476,0.00002572622],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019554529,0.00021408361,0.0007519854,0.00003466635,0.000037699814,0.0000026681691,0.00016556327,0.00017857025,0.00011216109],"category_scores_gemma":[0.000008453469,0.00010174019,0.00017630613,0.00015087437,0.00029381103,0.000019461768,0.00006305364,0.00023616325,0.0000012808605],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050727656,0.00006664287,0.0008010591,0.0007674197,0.00017213447,0.0000013072203,0.0002417387,0.0000046237074,0.000084375824,0.00003575652,0.00046945523,0.99730474],"study_design_scores_gemma":[0.00056387007,0.00015403656,0.0012460916,0.0063872,0.00029030137,0.0000177406,0.000031634674,0.0000075666107,0.00012488777,0.0011762168,0.98989105,0.00010940182],"about_ca_topic_score_codex":0.00026499515,"about_ca_topic_score_gemma":0.000034948316,"teacher_disagreement_score":0.99719536,"about_ca_system_score_codex":0.00021756347,"about_ca_system_score_gemma":0.00036584446,"threshold_uncertainty_score":0.41488445},"labels":[],"label_agreement":null},{"id":"W2012617565","doi":"10.1038/cdd.2010.146","title":"Bnip3 impairs mitochondrial bioenergetics and stimulates mitochondrial turnover","year":2010,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":292,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Institutes of Health; National Heart, Lung, and Blood Institute; University of Pennsylvania; American Heart Association","keywords":"Autophagy; Cell biology; Mitochondrion; Programmed cell death; Biology; Cytosol; Bioenergetics; DNAJA3; Mitochondrial DNA; Apoptosis; mitochondrial fusion; Biochemistry; Gene","score_opus":0.007797112038801274,"score_gpt":0.2394843432743859,"score_spread":0.23168723123558463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012617565","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968894,0.0005146666,0.00051726546,0.00009748214,0.001185972,0.00026490501,0.00001472194,0.000053164313,0.00046239462],"genre_scores_gemma":[0.99732643,0.00017035236,0.0007819475,0.00013055131,0.0008589407,0.000010003558,0.0001262512,0.000019365683,0.00057615555],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99921805,0.000017141449,0.00017474894,0.00025194124,0.00015060899,0.00018748573],"domain_scores_gemma":[0.9994284,0.000045726098,0.00006415724,0.00017864715,0.000050211365,0.00023287603],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002234145,0.00016460208,0.00019516422,0.00007713002,0.00009861701,0.000056770532,0.000035443412,0.00016289062,0.00020470064],"category_scores_gemma":[0.00003265881,0.00013100241,0.000063053856,0.000049062593,0.00005504871,0.00008174412,0.000026254593,0.00017081505,0.000009641066],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00063816726,0.00031534178,0.063966535,0.00009854818,0.00006829685,0.000013191092,0.00030626147,0.0000020231182,0.9297746,0.00085740053,0.0007537279,0.003205919],"study_design_scores_gemma":[0.011926214,0.00059036433,0.7583634,0.00004639688,0.00058168644,0.00003392805,0.000053751497,0.0063703964,0.21439785,0.0039985366,0.0031712302,0.00046623297],"about_ca_topic_score_codex":0.000017912811,"about_ca_topic_score_gemma":0.000008655007,"teacher_disagreement_score":0.71537673,"about_ca_system_score_codex":0.000008057023,"about_ca_system_score_gemma":0.000032323132,"threshold_uncertainty_score":0.5342123},"labels":[],"label_agreement":null},{"id":"W2013251910","doi":"10.3109/10428194.2011.604752","title":"Regulation of autophagy in hematological malignancies: role of reactive oxygen species","year":2011,"lang":"en","type":"review","venue":"Leukemia & lymphoma/Leukemia and lymphoma","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Research Manitoba; CancerCare Manitoba","funders":"","keywords":"Autophagy; Cancer research; Programmed cell death; Reactive oxygen species; Biology; Drug resistance; Bone marrow; Cancer; Myeloid; Immunology; Medicine; Apoptosis; Cell biology; Internal medicine","score_opus":0.026581577183491377,"score_gpt":0.27612582090251764,"score_spread":0.24954424371902625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013251910","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13151477,0.8588799,0.000008733922,0.000004307507,0.0001409033,0.0011823912,0.00010992304,0.000089279136,0.008069754],"genre_scores_gemma":[0.10215764,0.89559054,0.00030675402,0.000069094756,0.00017267447,0.00017694834,0.00030763927,0.00012585772,0.0010928398],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99536806,0.0002774282,0.0020763837,0.0010196586,0.00056532904,0.0006931108],"domain_scores_gemma":[0.99654365,0.0003812469,0.0014621122,0.0010796225,0.0002057656,0.00032762272],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00039194792,0.0009924177,0.0045312936,0.0007386669,0.000088360226,0.00002025825,0.0004540047,0.0013540584,0.00027054173],"category_scores_gemma":[0.00013800777,0.0007984698,0.00096548937,0.0008589875,0.000659417,0.00020069722,0.00021212449,0.00020810882,0.00003026944],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009913913,0.0006291896,0.0003108341,0.017121224,0.00092630903,0.00034102326,0.0014301039,0.0000014205704,0.0011609744,0.014531331,0.0002821499,0.9622741],"study_design_scores_gemma":[0.013862439,0.0012007477,0.064185485,0.036783293,0.0034867227,0.002701127,0.00095468183,0.00022399292,0.01237238,0.0055188714,0.8568448,0.0018654801],"about_ca_topic_score_codex":0.0005396238,"about_ca_topic_score_gemma":0.000011705029,"teacher_disagreement_score":0.96040857,"about_ca_system_score_codex":0.003368383,"about_ca_system_score_gemma":0.00498403,"threshold_uncertainty_score":0.9999424},"labels":[],"label_agreement":null},{"id":"W2013431910","doi":"10.4161/auto.6.1.10600","title":"Spermidine: A novel autophagy inducer and longevity elixir","year":2010,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":182,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ligue Contre le Cancer; Fondation pour la Recherche Médicale; Institute of Cancer Research; Institut National Du Cancer; Austrian Science Fund; European Commission","keywords":"Spermidine; Biology; Autophagy; Putrescine; Saccharomyces cerevisiae; Spermine; Cell biology; Caenorhabditis elegans; Drosophila melanogaster; ATG5; Polyamine; Yeast; Biochemistry; Gene; Enzyme","score_opus":0.009830718952673708,"score_gpt":0.2790036781399697,"score_spread":0.26917295918729595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013431910","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99065477,0.0008348672,0.00015334794,0.0007730794,0.0007289464,0.0004337849,0.000021169732,0.00028126672,0.006118745],"genre_scores_gemma":[0.9913916,0.0001110068,0.0015849398,0.0025092466,0.0007089621,0.000040921987,0.000026148864,0.00006074218,0.0035664297],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983092,0.000023004035,0.0003304253,0.00053840963,0.0003332347,0.00046575506],"domain_scores_gemma":[0.998588,0.00008036777,0.00009895622,0.0006778234,0.000100164136,0.00045466056],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00023060401,0.0003180154,0.00045803885,0.00014944145,0.00014541799,0.000047938964,0.00016101993,0.00029693116,0.0017906917],"category_scores_gemma":[0.000134493,0.00027289861,0.00015179979,0.00023762285,0.00023682485,0.00018924379,0.00010087646,0.0006409072,0.0002356974],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026627968,0.001016202,0.005603664,0.00012535468,0.00026848275,0.00045680103,0.00053002924,8.870902e-7,0.9349322,0.014083439,0.0015218697,0.041194797],"study_design_scores_gemma":[0.0050533665,0.0003467185,0.60874945,0.000057189114,0.0002202613,0.0009311883,0.000041416,0.00065916794,0.33648288,0.0017032928,0.045221582,0.0005334967],"about_ca_topic_score_codex":0.000060789807,"about_ca_topic_score_gemma":0.00001677374,"teacher_disagreement_score":0.6031458,"about_ca_system_score_codex":0.00003040739,"about_ca_system_score_gemma":0.00019393217,"threshold_uncertainty_score":0.99997234},"labels":[],"label_agreement":null},{"id":"W2013471405","doi":"10.4161/auto.24083","title":"Glutamate dehydrogenase contributes to leucine sensing in the regulation of autophagy","year":2013,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institut National Du Cancer; Institute of Cancer Research; Institut National de la Santé et de la Recherche Médicale","keywords":"Autophagy; Biology; Leucine; Amino acid; Biochemistry; Catabolism; Glutamate dehydrogenase; mTORC1; Cell biology; Glutamate receptor; PI3K/AKT/mTOR pathway; Dehydrogenase; Enzyme; Reactive oxygen species; Signal transduction; Apoptosis; Receptor","score_opus":0.010865568895794014,"score_gpt":0.2657369527316071,"score_spread":0.2548713838358131,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013471405","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936399,0.0010414516,0.0004886791,0.0024711953,0.00012166448,0.0010385076,0.0000063132097,0.0000699692,0.001122356],"genre_scores_gemma":[0.9951385,0.000022117305,0.00057260337,0.0036422869,0.0000971278,0.000037084967,0.000026582065,0.00002530635,0.00043839458],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99851584,0.00011417923,0.00047841313,0.00026210153,0.00029134593,0.00033812865],"domain_scores_gemma":[0.99892336,0.00016230471,0.00011691978,0.0005379806,0.00014800513,0.000111412846],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034627196,0.00018592243,0.00040137523,0.00021859273,0.000063948515,0.0000263228,0.00014668122,0.0001023859,0.00036768857],"category_scores_gemma":[0.00014015092,0.00013098783,0.000115946605,0.0005558789,0.00007647402,0.000119529715,0.000035880843,0.00014007569,0.00020888117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034008265,0.00047582696,0.0023390113,0.00014026798,0.0002059009,0.00015699856,0.002090724,0.00031185275,0.9460495,0.0069633173,0.0037285574,0.03719796],"study_design_scores_gemma":[0.002355418,0.00022269125,0.49134788,0.0001532267,0.00007684097,0.00006178386,0.00018473373,0.0053964662,0.4931619,0.0051525915,0.0017373607,0.00014910377],"about_ca_topic_score_codex":0.00034943162,"about_ca_topic_score_gemma":0.000014611781,"teacher_disagreement_score":0.48900887,"about_ca_system_score_codex":0.000066305794,"about_ca_system_score_gemma":0.00009060553,"threshold_uncertainty_score":0.53415287},"labels":[],"label_agreement":null},{"id":"W2013828402","doi":"10.1111/febs.13249","title":"Parkin structure and function","year":2015,"lang":"en","type":"review","venue":"FEBS Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":243,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Parkin; Function (biology); Structure function; Computational biology; Biology; Cell biology; Physics; Medicine; Parkinson's disease","score_opus":0.05295041929725706,"score_gpt":0.36025535287683663,"score_spread":0.30730493357957955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013828402","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011058712,0.9983417,0.000018012983,0.000023207449,0.0006508775,0.00018491861,0.000019904703,0.00001648476,0.0006342984],"genre_scores_gemma":[0.0000632458,0.9966957,0.00005147859,0.00014216117,0.0021612279,0.000002838096,0.0000492179,0.000032479806,0.00080163934],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99913013,0.00007608482,0.0002768958,0.00013486885,0.00023554775,0.00014645304],"domain_scores_gemma":[0.9992252,0.000015918014,0.00022649464,0.00014647876,0.00007639892,0.0003094916],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016215512,0.00020340389,0.0008204797,0.00011739484,0.00006936622,0.00004511495,0.00005524465,0.00022624483,0.0005589643],"category_scores_gemma":[0.000021067586,0.00012602197,0.00020900037,0.00008603539,0.0000288369,0.00005070407,0.000016356404,0.00068991317,0.000034658373],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003576629,0.000013696559,0.000009903867,0.0014547476,0.00035792764,0.00015904124,0.000015885886,3.7214416e-8,3.042272e-7,0.00002505428,0.009915909,0.9880117],"study_design_scores_gemma":[0.0005072346,0.00016894283,0.00007871417,0.0037929334,0.0021151556,0.005945117,0.000005339458,6.975886e-7,3.969399e-7,0.00077697146,0.9864976,0.00011089714],"about_ca_topic_score_codex":4.943921e-7,"about_ca_topic_score_gemma":1.6682517e-7,"teacher_disagreement_score":0.98790085,"about_ca_system_score_codex":0.00007551096,"about_ca_system_score_gemma":0.00046365755,"threshold_uncertainty_score":0.61202675},"labels":[],"label_agreement":null},{"id":"W2013961803","doi":"10.3389/fneur.2013.00100","title":"Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up?","year":2013,"lang":"en","type":"article","venue":"Frontiers in Neurology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Parkin; Mitophagy; PINK1; Neuroscience; Autophagy; Cell biology; Biology; Medicine; Parkinson's disease; Genetics; Internal medicine","score_opus":0.007106604523821498,"score_gpt":0.22642612141513102,"score_spread":0.21931951689130952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013961803","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98808813,0.004497131,0.00007224729,0.0045078,0.0012132477,0.000765135,0.000009375482,0.00003673133,0.00081017654],"genre_scores_gemma":[0.9909439,0.0024451097,0.00007622638,0.0057121664,0.00013968762,0.00012714605,0.000006575978,0.000030871794,0.0005183216],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99840355,0.00027448463,0.0003154839,0.00041615558,0.00016789338,0.0004224588],"domain_scores_gemma":[0.99923784,0.00010502217,0.000072227405,0.00040907587,0.000025212325,0.00015062913],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016266391,0.00019503733,0.00036280585,0.00018248553,0.000053857635,0.000018610923,0.0001634877,0.00015671951,0.00012258942],"category_scores_gemma":[0.0000732148,0.00014357762,0.000051824503,0.00016004687,0.0002488623,0.00011453643,0.000070803006,0.00048797196,0.000011520543],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023132781,0.0004269187,0.93833447,0.00007410617,0.000096209325,0.0020559372,0.0012254091,0.000039386898,0.0013994373,0.00046811014,0.022677202,0.030889517],"study_design_scores_gemma":[0.0056057596,0.00090596225,0.96255386,0.000022640697,0.000036625424,0.00012847176,0.00021853628,0.0016607293,0.0004711466,0.0057123764,0.022472084,0.00021179063],"about_ca_topic_score_codex":0.00022844005,"about_ca_topic_score_gemma":0.000049791666,"teacher_disagreement_score":0.030677726,"about_ca_system_score_codex":0.000026698528,"about_ca_system_score_gemma":0.000093213916,"threshold_uncertainty_score":0.5854925},"labels":[],"label_agreement":null},{"id":"W2014205131","doi":"10.1074/jbc.m407016200","title":"Human Light Chain 3/MAP1LC3B Is Cleaved at Its Carboxyl-terminal Met121 to Expose Gly120 for Lipidation and Targeting to Autophagosomal Membranes","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":240,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute for Basic Biology; Japan Society for the Promotion of Science; Institute of Genetics; Japan Private School Promotion Foundation","keywords":"Terminal (telecommunication); Membrane; Cell biology; Lipid-anchored protein; Chemistry; Engineering; Biochemistry; Biology; Autophagy; Telecommunications","score_opus":0.026675082499943784,"score_gpt":0.3034552162238241,"score_spread":0.27678013372388033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014205131","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950429,0.001012319,0.00008029654,0.0033250866,0.000079626894,0.00026409424,0.000016596918,0.000024238763,0.00015480802],"genre_scores_gemma":[0.9955147,0.00005998212,0.0011735271,0.0016498413,0.0011781272,0.00001659601,0.000014833566,0.000015764464,0.00037665883],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987388,0.000019648913,0.0005035602,0.0002595842,0.00020526168,0.0002731336],"domain_scores_gemma":[0.9989514,0.00004573355,0.00022893025,0.00012404397,0.00017700286,0.00047293646],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027338724,0.00019870259,0.00044251585,0.00004762704,0.00013239104,0.00002273921,0.00013181815,0.00020304561,0.00022097258],"category_scores_gemma":[0.0002610473,0.0001388512,0.00019375132,0.00009910356,0.000034810026,0.000054399585,0.00006517098,0.00017656572,0.000006875471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00090629375,0.00015980598,0.00039942694,0.00013541906,0.000077130935,0.00013772633,0.00033487554,0.000009394358,0.9969315,0.000011887599,0.00034988413,0.00054666447],"study_design_scores_gemma":[0.0022942862,0.0011044845,0.004579128,0.00015625796,0.00007130007,0.00029955723,0.00013961643,0.000011115584,0.98773736,0.0001695553,0.0032671287,0.00017018738],"about_ca_topic_score_codex":0.0000012924334,"about_ca_topic_score_gemma":2.2509693e-7,"teacher_disagreement_score":0.009194109,"about_ca_system_score_codex":0.00012727329,"about_ca_system_score_gemma":0.000057158555,"threshold_uncertainty_score":0.5662188},"labels":[],"label_agreement":null},{"id":"W2014707404","doi":"10.1083/jcb.200909154","title":"A yeast MAPK cascade regulates pexophagy but not other autophagy pathways","year":2010,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Universidad Complutense de Madrid; University of California, San Diego; National Institutes of Health; University of Alberta","keywords":"Autophagy; Cell biology; Biology; Signal transduction; Protein kinase A; MAPK/ERK pathway; Kinase; BAG3; Biochemistry; Apoptosis","score_opus":0.014772737103364785,"score_gpt":0.26010109720884134,"score_spread":0.24532836010547654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014707404","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951056,0.0013057466,0.000066525194,0.00027717714,0.0007175162,0.00013269669,0.000018236675,0.000022633218,0.0023538352],"genre_scores_gemma":[0.99442655,0.00024713035,0.0002966668,0.002351284,0.0009875074,0.0000018452213,0.0000028049656,0.00002795888,0.0016582679],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988804,0.00013322482,0.0004232035,0.00011695131,0.0001552045,0.000291018],"domain_scores_gemma":[0.998795,0.00015241538,0.0003676983,0.00036021645,0.0001453525,0.00017932085],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005696451,0.00017284296,0.00038895936,0.00011113193,0.00008292515,0.000008648073,0.0003089871,0.00020993187,0.0012884404],"category_scores_gemma":[0.000058172525,0.00009498171,0.00021545198,0.00008945327,0.00026142749,0.00004606205,0.00003971586,0.00060712954,0.000104818726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008623226,0.00014178744,0.000013603551,0.000012180169,0.000112294096,0.00007128108,0.00032697353,0.0000023586065,0.9952073,0.0004934492,0.0005114632,0.0022449794],"study_design_scores_gemma":[0.001538036,0.0006891677,0.0036102305,0.000018484292,0.00015283293,0.0009577528,0.00010168451,0.000042459444,0.9779129,0.0016867213,0.013192754,0.000096944976],"about_ca_topic_score_codex":0.000026745243,"about_ca_topic_score_gemma":0.0000042623924,"teacher_disagreement_score":0.017294375,"about_ca_system_score_codex":0.000021415271,"about_ca_system_score_gemma":0.00018702837,"threshold_uncertainty_score":0.9996245},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"}],"label_agreement":"agree"},{"id":"W2015228313","doi":"10.1016/j.bbamcr.2014.03.006","title":"Airway mesenchymal cell death by mevalonate cascade inhibition: Integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins","year":2014,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; GlaxoSmithKline; Canadian Institutes of Health Research; Marathon","keywords":"Autophagy; Unfolded protein response; Programmed cell death; Cell biology; Apoptosis; Simvastatin; Endoplasmic reticulum; Biology; Chemistry; Biochemistry; Endocrinology","score_opus":0.027547180158252523,"score_gpt":0.3162950412564913,"score_spread":0.2887478610982388,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015228313","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921263,0.00031252342,0.00048117345,0.0019974213,0.000034444947,0.0024423285,0.00006922612,0.0000902512,0.0024463648],"genre_scores_gemma":[0.99688387,0.00013000552,0.0013517364,0.00039631076,0.00009332601,0.00025845208,0.0001417756,0.000109467874,0.00063502946],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99451584,0.0017051676,0.0005657664,0.00092727767,0.0015432998,0.00074262306],"domain_scores_gemma":[0.997679,0.00030395697,0.00024137757,0.0009110077,0.00042725969,0.00043742426],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0017305651,0.0004740377,0.0005994404,0.00056291383,0.00027621462,0.00011132566,0.00028427065,0.00034064808,0.000030946263],"category_scores_gemma":[0.00026159713,0.00041191635,0.00026807588,0.0007623035,0.0004411386,0.00016053654,0.000197332,0.0008912591,0.000037833892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036630826,0.0010869286,9.725605e-7,0.00027141318,0.000077932615,0.000036325528,0.00041255777,0.0000015909059,0.9924632,0.00041806526,0.00037189273,0.0011960416],"study_design_scores_gemma":[0.00277792,0.0032267522,0.0007486168,0.00044963948,0.00008274872,0.0000042762713,0.0001226648,0.00058693514,0.9907399,0.0006806163,0.00021666486,0.00036330946],"about_ca_topic_score_codex":0.00017322104,"about_ca_topic_score_gemma":0.0000010675585,"teacher_disagreement_score":0.0047576297,"about_ca_system_score_codex":0.00016833628,"about_ca_system_score_gemma":0.0004471314,"threshold_uncertainty_score":0.9998333},"labels":[],"label_agreement":null},{"id":"W2015448890","doi":"10.1007/s13277-015-3425-z","title":"The role of hypoxia-inducible factor-1α in radiation-induced autophagic cell death in breast cancer cells","year":2015,"lang":"en","type":"article","venue":"Tumor Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autophagy; Radioresistance; PI3K/AKT/mTOR pathway; Radiosensitivity; Gene silencing; Protein kinase B; Apoptosis; Biology; Molecular biology; Cancer research; Cell growth; Transfection; Programmed cell death; Chemistry; Cell biology; Cell culture; Signal transduction; Medicine; Gene; Internal medicine; Biochemistry; Radiation therapy","score_opus":0.021784317956219212,"score_gpt":0.2921088600113567,"score_spread":0.2703245420551375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015448890","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99413574,0.0034406486,0.0000010675002,0.00030173178,0.00022797874,0.00028434824,0.000046332996,0.000019601619,0.0015425781],"genre_scores_gemma":[0.9992295,0.00018869751,0.000016379636,0.00027292475,0.000111710644,0.000044532742,0.000012338663,0.000015027368,0.00010887748],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989775,0.00011526648,0.00029561136,0.00022112644,0.00009199274,0.00029851636],"domain_scores_gemma":[0.9993441,0.00008859795,0.00011729583,0.0002790206,0.000052866086,0.000118087475],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001995744,0.00013228983,0.0002985216,0.0001223582,0.000023994153,0.0000042791908,0.00014593784,0.000092238435,0.00013285634],"category_scores_gemma":[0.00002070384,0.00008998679,0.00005182603,0.00021245147,0.000056180485,0.00003328127,0.000028400496,0.00017761231,0.000035352394],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043279643,0.00034916788,0.28864744,0.000017199349,0.00003467084,0.00004679324,0.0007225581,0.000023011045,0.6996986,0.0006275691,0.00008951794,0.009310636],"study_design_scores_gemma":[0.002441878,0.00018474355,0.5173672,0.00001990625,0.000014510383,0.000014239959,0.00026398647,0.0003242779,0.4764887,0.0016910853,0.0010782444,0.00011126222],"about_ca_topic_score_codex":0.0016459575,"about_ca_topic_score_gemma":0.00008119055,"teacher_disagreement_score":0.22871973,"about_ca_system_score_codex":0.00012807857,"about_ca_system_score_gemma":0.00041490683,"threshold_uncertainty_score":0.36695546},"labels":[],"label_agreement":null},{"id":"W2015828638","doi":"10.3892/ijo.2014.2297","title":"Feroniellin A-induced autophagy causes apoptosis in multidrug-resistant human A549 lung cancer cells","year":2014,"lang":"en","type":"article","venue":"International Journal of Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":37,"is_retracted":true,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Division of Chemistry; Office of the Higher Education Commission; Korea Research Institute of Bioscience and Biotechnology; National Research Foundation","keywords":"Biology; Apoptosis; Autophagy; Downregulation and upregulation; Multiple drug resistance; Cancer cell; Cancer research; ATG5; Programmed cell death; Cell biology; Multidrug resistance-associated protein 2; PI3K/AKT/mTOR pathway; Cancer; Drug resistance; ATP-binding cassette transporter; Biochemistry; Gene; Microbiology; Transporter","score_opus":0.024453589791842634,"score_gpt":0.3870455390492786,"score_spread":0.36259194925743593,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015828638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99455076,0.00041960075,0.0001435638,0.0018391599,0.001732661,0.00012307186,0.000007868968,0.000012252709,0.0011710325],"genre_scores_gemma":[0.9966426,0.00032885093,0.00034586192,0.0013591999,0.001022089,0.000011540839,0.0000050624667,0.000020275977,0.00026454846],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99843997,0.0001295608,0.00065302174,0.00015553173,0.00041644485,0.00020547504],"domain_scores_gemma":[0.9987542,0.00016574055,0.0004373297,0.0001199577,0.00037323806,0.00014955316],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036864253,0.00014192407,0.00042554777,0.00035274916,0.00003527134,0.000017412147,0.00029301664,0.0001412451,0.0007234471],"category_scores_gemma":[0.000070018854,0.0001191114,0.00016934962,0.00008316502,0.000056530156,0.000106348605,0.00003635588,0.00035882957,0.000012921259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015137776,0.0012699708,0.0082479175,0.000031616633,0.0008172586,0.0007725339,0.0007835203,0.00035898807,0.95733887,0.0010519263,0.0020043293,0.025809295],"study_design_scores_gemma":[0.016575145,0.0029903923,0.1009188,0.00057399244,0.00031651327,0.0002731336,0.00022730223,0.0022038494,0.8451064,0.0009369517,0.029533273,0.00034423487],"about_ca_topic_score_codex":0.0002496491,"about_ca_topic_score_gemma":0.00015700534,"teacher_disagreement_score":0.112232454,"about_ca_system_score_codex":0.00068249524,"about_ca_system_score_gemma":0.00038511306,"threshold_uncertainty_score":0.7921239},"labels":[],"label_agreement":null},{"id":"W2016363647","doi":"10.1101/pdb.prot080333","title":"Monitoring Autophagic Flux Using Ref(2)P, the <i>Drosophila</i> p62 Ortholog","year":2014,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Ubiquitin; Drosophila (subgenus); Cell biology; Flux (metallurgy); Proteasome; Scaffold protein; Chemistry; Protein degradation; Biology; Biochemistry; Gene; Signal transduction","score_opus":0.038967509216727265,"score_gpt":0.32642123687516994,"score_spread":0.2874537276584427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016363647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93359786,0.0004438608,0.000886253,0.00055758463,0.0003708771,0.06159406,0.0000036485283,0.00054308,0.002002759],"genre_scores_gemma":[0.9604353,0.000007573231,0.0015511179,0.00076119986,0.0013810352,0.035388615,4.2188927e-7,0.00008237984,0.00039240546],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99809355,0.00012444335,0.00040088373,0.0004456882,0.0004229834,0.000512483],"domain_scores_gemma":[0.9983466,0.0000983117,0.00018125953,0.0010431311,0.00010642442,0.00022422381],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062596204,0.00029143458,0.00040307728,0.00008134795,0.000360579,0.00009297002,0.00033780315,0.0001476937,0.00008727527],"category_scores_gemma":[0.000141473,0.00021473106,0.00019633213,0.00024711865,0.00014033375,0.00013159112,0.00011650728,0.0004200017,0.00012595902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004899728,0.00049550115,0.08399639,0.0005188964,0.00024515035,0.00022843693,0.00014675866,0.0001499933,0.89279455,0.018124437,0.0001889717,0.0026209417],"study_design_scores_gemma":[0.004118823,0.00050719484,0.24534672,0.0015011237,0.0001912071,0.000021881067,0.000015974772,0.0024681857,0.6549804,0.00043738246,0.08984337,0.00056772993],"about_ca_topic_score_codex":0.000016104756,"about_ca_topic_score_gemma":2.3585663e-7,"teacher_disagreement_score":0.23781414,"about_ca_system_score_codex":0.00011834928,"about_ca_system_score_gemma":0.00014972492,"threshold_uncertainty_score":0.87564784},"labels":[],"label_agreement":null},{"id":"W2017532292","doi":"10.4161/auto.5.3.7444","title":"Autophagy promotes caspase-dependent cell death during Drosophila development","year":2009,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Programmed cell death; Cell biology; Biology; Downregulation and upregulation; Apoptosis; Caspase; Embryonic stem cell; Cell fate determination; Genetics; Transcription factor; Gene","score_opus":0.01431355615363519,"score_gpt":0.26126330953442034,"score_spread":0.24694975338078515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017532292","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98726296,0.0020911288,0.0000787406,0.0004968823,0.00025407513,0.0007142603,0.000007291841,0.00060129666,0.008493336],"genre_scores_gemma":[0.9867576,0.000089543224,0.0020922928,0.0014919734,0.0003781745,0.000055890923,0.000045636203,0.000067808985,0.009021107],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99726087,0.000053700598,0.00059043785,0.00069013034,0.0006323923,0.00077247346],"domain_scores_gemma":[0.9985181,0.00003475185,0.00016583018,0.000686108,0.000107649736,0.0004875516],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001890216,0.00046583833,0.0005603612,0.00022234795,0.0003083312,0.000057523357,0.00026143627,0.00021878953,0.000770692],"category_scores_gemma":[0.00003159605,0.000421993,0.00020911728,0.00024239368,0.000049135404,0.00017787793,0.00006651421,0.00034751443,0.00065076014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009664529,0.0046182014,0.0026605227,0.0004983435,0.00048556514,0.00961139,0.0033618386,0.00006196719,0.93923175,0.002768228,0.0007499737,0.034985766],"study_design_scores_gemma":[0.0025777458,0.00035837526,0.24798903,0.00008740724,0.00009310158,0.00027693415,0.000030360128,0.00011735517,0.7461238,0.00083756604,0.0011204138,0.00038791835],"about_ca_topic_score_codex":0.000015654394,"about_ca_topic_score_gemma":0.0000017755777,"teacher_disagreement_score":0.2453285,"about_ca_system_score_codex":0.00026308533,"about_ca_system_score_gemma":0.00040835261,"threshold_uncertainty_score":0.9998232},"labels":[],"label_agreement":null},{"id":"W2018111833","doi":"10.1016/j.ntt.2012.03.005","title":"Glyphosate induced cell death through apoptotic and autophagic mechanisms","year":2012,"lang":"en","type":"article","venue":"Neurotoxicology and Teratology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":120,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Toronto; University of New South Wales; Neuroscience Research Australia","keywords":"Autophagy; Apoptosis; Programmed cell death; Glyphosate; Crosstalk; Cell biology; Parkinsonism; Viability assay; Biology; Cell; Chemistry; Disease; Biochemistry; Medicine; Biotechnology; Internal medicine","score_opus":0.028444791246708154,"score_gpt":0.2930501993807133,"score_spread":0.2646054081340051,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018111833","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99479884,0.0012686609,0.0001667182,0.00067805586,0.0004436178,0.0005470631,0.0000031927245,0.00008936424,0.0020045],"genre_scores_gemma":[0.98958224,0.00013727412,0.000674941,0.009229538,0.00010029575,0.00008514247,0.0000069836356,0.000025090856,0.00015852335],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876213,0.00015336841,0.00021138998,0.00032310042,0.00007032746,0.00047968846],"domain_scores_gemma":[0.9993362,0.000116978736,0.00007182575,0.00021552613,0.00002303169,0.00023643798],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009602633,0.00021631384,0.00041257308,0.000078090365,0.00014421169,0.000010539962,0.000056737423,0.0003172325,0.00021889449],"category_scores_gemma":[0.000027514248,0.00018336068,0.00004619262,0.00007754096,0.00013767599,0.00012623209,0.00006845533,0.00031830533,0.00004387015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00068322296,0.0010161074,0.038541164,0.00018054052,0.0001592313,0.00064919563,0.0012884089,1.6039935e-7,0.85928243,0.09576428,0.00021797535,0.0022172646],"study_design_scores_gemma":[0.0077577583,0.0034619076,0.38302925,0.000026517051,0.0004180574,0.0053773886,0.000083325955,0.0001250777,0.5703449,0.024058484,0.0048116883,0.0005056026],"about_ca_topic_score_codex":0.000009020374,"about_ca_topic_score_gemma":9.285673e-7,"teacher_disagreement_score":0.34448808,"about_ca_system_score_codex":0.00001132108,"about_ca_system_score_gemma":0.000043785847,"threshold_uncertainty_score":0.74772316},"labels":[],"label_agreement":null},{"id":"W2018302034","doi":"10.1016/j.molcel.2014.05.021","title":"WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12–5-16L1","year":2014,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":875,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; Cancer Research UK","keywords":"Autophagy; ATG16L1; Cell biology; ATG12; Autophagosome; Biology; Effector; Phosphatidylinositol; Endoplasmic reticulum; Biochemistry; ATG5; Signal transduction; Apoptosis","score_opus":0.003947345710606803,"score_gpt":0.20499025721176226,"score_spread":0.20104291150115544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018302034","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96494645,0.0020498647,0.02599812,0.00043836253,0.000037484195,0.00040192582,0.00000984066,0.00009690569,0.0060210247],"genre_scores_gemma":[0.99526334,0.00010212858,0.0012223144,0.0027198794,0.000065800115,0.000028056289,0.00011821774,0.00003653373,0.0004437257],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990493,0.0000665366,0.00020261647,0.00024305527,0.00022488146,0.00021358617],"domain_scores_gemma":[0.99937373,0.000024472578,0.00011365569,0.00026199166,0.00008048687,0.00014563928],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015010899,0.0001565872,0.0002013121,0.000046557318,0.00009671114,0.000032488773,0.00005963009,0.00013214577,0.000041871128],"category_scores_gemma":[0.000023206165,0.00013523505,0.000045125296,0.00010756726,0.00005911415,0.00011983554,0.000017747983,0.00019998424,0.000040648552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046698883,0.00022974527,0.0021704284,0.00047605313,0.00009535243,0.00015043099,0.0012094232,0.00007180396,0.95647407,0.0011644869,0.0010406569,0.036450557],"study_design_scores_gemma":[0.008268977,0.0013030628,0.009645461,0.00038392487,0.00027845465,0.00010547901,0.0001988134,0.01149589,0.8909743,0.001435929,0.07526047,0.0006492905],"about_ca_topic_score_codex":0.000006449224,"about_ca_topic_score_gemma":6.0355165e-7,"teacher_disagreement_score":0.07421981,"about_ca_system_score_codex":0.000023852539,"about_ca_system_score_gemma":0.000029577537,"threshold_uncertainty_score":0.55147254},"labels":[],"label_agreement":null},{"id":"W2019148785","doi":"10.1371/journal.pone.0051469","title":"Autophagy and Apoptosis Are Differentially Induced in Neurons and Astrocytes Treated with an In Vitro Mimic of the Ischemic Penumbra","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; University of California, San Diego; National Institutes of Health; Heart and Stroke Foundation of Canada","keywords":"Penumbra; Cell biology; Autophagy; Biology; Programmed cell death; Apoptosis; Vacuole; Mitochondrion; Cytoplasm; Biochemistry; Ischemia; Medicine","score_opus":0.028973181045163776,"score_gpt":0.23338597233031838,"score_spread":0.2044127912851546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019148785","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99914956,0.000359003,5.10558e-7,0.00010604471,0.0000060354573,0.00029981535,0.000009752347,0.00001574037,0.00005352948],"genre_scores_gemma":[0.99960005,0.00005348882,0.00013168386,0.00010689879,0.000028509392,0.000023946792,0.0000089510295,0.000017737577,0.000028749786],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99933875,0.000052222502,0.0001398628,0.0001446423,0.00013998675,0.00018453691],"domain_scores_gemma":[0.99958634,0.00003107351,0.000070461116,0.00019405367,0.000018663603,0.00009939753],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000042043404,0.000116670766,0.00027823303,0.000076952856,0.000021813144,0.0000062505146,0.000053204134,0.00005592347,0.000020327196],"category_scores_gemma":[0.000020464024,0.00007774248,0.000017183347,0.00013345429,0.00006273455,0.00009511954,0.000028652597,0.00015150575,5.720292e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048497866,0.0011708061,0.2877397,0.000066356704,0.000060133018,0.0000019372458,0.00032830675,4.812244e-8,0.70997167,0.0000026982416,8.536161e-7,0.00017252016],"study_design_scores_gemma":[0.0012686299,0.00011702478,0.47345155,0.0001483103,0.00008446765,0.000002208442,0.0000630562,0.000046470224,0.5247749,0.0000025038416,2.603264e-7,0.000040573625],"about_ca_topic_score_codex":0.000062534564,"about_ca_topic_score_gemma":0.000020084817,"teacher_disagreement_score":0.18571189,"about_ca_system_score_codex":0.000016643433,"about_ca_system_score_gemma":0.000025019286,"threshold_uncertainty_score":0.31702462},"labels":[],"label_agreement":null},{"id":"W2019763279","doi":"10.1016/j.bmc.2015.04.064","title":"Development of fluorescent peptide substrates and assays for the key autophagy-initiating cysteine protease enzyme, ATG4B","year":2015,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Drug Research and Development; Simon Fraser University","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Peptide; Förster resonance energy transfer; Enzyme; Substrate (aquarium); Protease; Cleavage (geology); Cysteine; Biochemistry; Combinatorial chemistry; Cysteine protease; Fluorescence; Biology","score_opus":0.04296820150825718,"score_gpt":0.2843415087248843,"score_spread":0.24137330721662711,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019763279","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99053574,0.0069003142,0.0004383559,0.00064113166,0.0000880995,0.0007091143,0.000018058972,0.000064868,0.0006043182],"genre_scores_gemma":[0.9960515,0.00005118019,0.0026514796,0.00023751013,0.00048488146,0.00009160846,0.00006321383,0.00003373886,0.0003349265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984283,0.000017095641,0.000494587,0.0002899434,0.00046882915,0.00030125226],"domain_scores_gemma":[0.998732,0.00013126401,0.00021509264,0.00031026054,0.00023257779,0.00037884046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00060148205,0.00023591369,0.00036017885,0.000023722774,0.00012108494,0.000012796368,0.00015755159,0.00012149961,0.00011028912],"category_scores_gemma":[0.00045324807,0.00015751287,0.000070416325,0.000128852,0.00018107872,0.00003965596,0.00005427015,0.00019088198,0.000005339327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005915949,0.00024482972,0.0012927133,0.0010248316,0.00029619483,0.000057662503,0.0023849118,5.0206467e-7,0.9883092,0.00004130068,0.0011949704,0.00456127],"study_design_scores_gemma":[0.0034622187,0.00017116747,0.0038530186,0.00037801327,0.00023230413,0.0001271574,0.002246507,0.0002656188,0.985663,0.000056815472,0.003378944,0.00016522531],"about_ca_topic_score_codex":0.000012148863,"about_ca_topic_score_gemma":0.0000014638551,"teacher_disagreement_score":0.006849134,"about_ca_system_score_codex":0.00010199851,"about_ca_system_score_gemma":0.0008988551,"threshold_uncertainty_score":0.64231884},"labels":[],"label_agreement":null},{"id":"W2020309443","doi":"10.4161/15548627.2014.981914","title":"Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity","year":2014,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; Biotechnology and Biological Sciences Research Council; Cancer Research UK","keywords":"ATG12; ATG5; Ubiquitin; Proteasome; Cell biology; Autophagy; Biology; Proteasome inhibitor; Protein degradation; Programmed cell death; Lipid-anchored protein; Apoptosis; Biochemistry","score_opus":0.012726183877052079,"score_gpt":0.26426477002517484,"score_spread":0.25153858614812274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020309443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971859,0.000262167,0.00044994117,0.00030382542,0.00004781023,0.0005127039,0.000002473276,0.00006710225,0.00116807],"genre_scores_gemma":[0.9980542,0.00002243529,0.000404571,0.000091096415,0.0000782883,0.00003425032,0.000014874445,0.0000150111055,0.0012852739],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992793,0.000060521415,0.00015330556,0.00018659333,0.00018539025,0.00013486689],"domain_scores_gemma":[0.99948335,0.000049307182,0.00011735759,0.00017765912,0.00009394491,0.00007839837],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001781124,0.00010505713,0.00020554797,0.0000718613,0.000048806196,0.0000090230105,0.000039751467,0.00007535161,0.00007704718],"category_scores_gemma":[0.00013144138,0.00009102399,0.000044263972,0.00010466325,0.00005641905,0.00014938966,0.00001977497,0.00007247005,0.000011268323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005378078,0.0006579204,0.0046509425,0.0007236016,0.00014262345,0.000008830225,0.00037882093,0.000008391219,0.7311821,0.019089028,0.00009389838,0.24252607],"study_design_scores_gemma":[0.00097551,0.0003369441,0.317387,0.00006342396,0.000053445066,0.000015898302,0.00000769075,0.004399749,0.67565703,0.0008172169,0.00021353253,0.00007254081],"about_ca_topic_score_codex":0.000009739072,"about_ca_topic_score_gemma":8.825107e-7,"teacher_disagreement_score":0.31273606,"about_ca_system_score_codex":0.0000216235,"about_ca_system_score_gemma":0.000046087254,"threshold_uncertainty_score":0.37118506},"labels":[],"label_agreement":null},{"id":"W2020345771","doi":"10.1139/y2012-051","title":"Resveratrol protects H9c2 embryonic rat heart derived cells from oxidative stress by inducing autophagy: role of p38 mitogen-activated protein kinase","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Science and Technology Department of Zhejiang Province","keywords":"Resveratrol; Autophagy; p38 mitogen-activated protein kinases; Oxidative stress; Protein kinase A; Apoptosis; Programmed cell death; MAPK/ERK pathway; Cell biology; Viability assay; Chemistry; Kinase; Biology; Molecular biology; Biochemistry","score_opus":0.010268204602290904,"score_gpt":0.2600838342779362,"score_spread":0.24981562967564527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020345771","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894015,0.008944375,0.0000061864635,0.00034551942,0.0006383897,0.0005270593,0.00010827421,0.0000073288757,0.000021338557],"genre_scores_gemma":[0.99834126,0.000064911575,0.00009496222,0.0008365787,0.00051584514,0.000026042067,0.000026996615,0.000022350292,0.000071079805],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984993,0.00039384438,0.0003465226,0.00018975193,0.00008661161,0.00048397883],"domain_scores_gemma":[0.99842805,0.00010040898,0.00034732383,0.00012689931,0.0001603032,0.0008370243],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016264751,0.00020936638,0.00057651993,0.00017805587,0.0001358137,0.000005405057,0.00012566488,0.00023603125,0.0018869414],"category_scores_gemma":[0.000028636421,0.00018273758,0.00010898264,0.0001263894,0.0002914047,0.00016967524,0.000016988906,0.00056480453,0.0000050273634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009563526,0.0001426836,0.0006801255,0.000053425923,0.0005258496,0.000049539805,0.0010283535,0.000009594204,0.9941433,0.000008677411,0.0020278527,0.00037423393],"study_design_scores_gemma":[0.0027865143,0.0006548724,0.005531238,0.0000773885,0.00017884433,0.00003140502,0.0002014343,0.00001761981,0.9870883,0.00019916812,0.0030918384,0.00014133047],"about_ca_topic_score_codex":0.001170698,"about_ca_topic_score_gemma":0.00007396106,"teacher_disagreement_score":0.008939705,"about_ca_system_score_codex":0.00008733111,"about_ca_system_score_gemma":0.00091922365,"threshold_uncertainty_score":0.99902546},"labels":[],"label_agreement":null},{"id":"W2020720216","doi":"10.4161/auto.26929","title":"Role of class III phosphatidylinositol 3-kinase during programmed nuclear death of <i>Tetrahymena thermophila</i>","year":2013,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Macronucleus; Biology; Tetrahymena; Cell biology; Autophagosome; Autophagy; Fragmentation (computing); Genetics; Ciliate; Apoptosis","score_opus":0.00593059599395462,"score_gpt":0.2246615323636893,"score_spread":0.21873093636973467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020720216","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890362,0.002884527,0.0000038976277,0.00014069934,0.00008078562,0.00090305146,0.000009934267,0.00013247183,0.0068084355],"genre_scores_gemma":[0.99845904,0.00014333651,0.000374957,0.00027667114,0.00010330515,0.000056487854,0.000014301351,0.00006118909,0.0005107252],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99835104,0.000040833307,0.0005348936,0.0003034701,0.00037809013,0.0003916559],"domain_scores_gemma":[0.9987142,0.00004479805,0.00026297505,0.00058011716,0.00016922115,0.00022870378],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000824627,0.00024282257,0.0005515035,0.000110132096,0.00006824985,0.000013573414,0.00021209415,0.00014712833,0.0011025389],"category_scores_gemma":[0.000023513003,0.00020585752,0.00024772546,0.00021506037,0.00014520946,0.00014966296,0.00006116314,0.00017384868,0.00008786211],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004877221,0.0012976367,0.0063369577,0.00029476534,0.0003947379,0.00006175231,0.0010927669,0.000005467089,0.9642194,0.0049249195,0.00014009235,0.02074377],"study_design_scores_gemma":[0.003303946,0.0004376846,0.21182792,0.00013621303,0.00012990145,0.000025926893,0.00024528173,0.00035170154,0.7812068,0.0011798762,0.0009756236,0.00017914912],"about_ca_topic_score_codex":0.00027544587,"about_ca_topic_score_gemma":8.397451e-7,"teacher_disagreement_score":0.20549096,"about_ca_system_score_codex":0.000041063187,"about_ca_system_score_gemma":0.0000860182,"threshold_uncertainty_score":0.9998106},"labels":[],"label_agreement":null},{"id":"W2020722847","doi":"10.1111/cns.12325","title":"BNIP3 Interacting with LC3 Triggers Excessive Mitophagy in Delayed Neuronal Death in Stroke","year":2014,"lang":"en","type":"article","venue":"CNS Neuroscience & Therapeutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":274,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Canadian Stroke Network; University of Manitoba; Manitoba Health Research Council","keywords":"Mitophagy; Autophagy; Mitochondrion; Cell biology; Programmed cell death; Apoptosis; Biology; Downregulation and upregulation; Neuroscience; Biochemistry; Gene","score_opus":0.033594646429884516,"score_gpt":0.31272066752720384,"score_spread":0.2791260210973193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020722847","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966646,0.0001536808,0.0009085666,0.0005489863,0.00043080133,0.00034086133,0.0000054056673,0.00005709623,0.00089003326],"genre_scores_gemma":[0.99126506,0.00013151413,0.00017700442,0.007990173,0.000090331065,0.000025832413,0.0000033631143,0.00003800383,0.0002787471],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99792665,0.00015698912,0.00035845113,0.00055427547,0.00044861028,0.000555046],"domain_scores_gemma":[0.9989743,0.00024820652,0.000150811,0.00040009437,0.00005473911,0.00017180644],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024850442,0.00026240177,0.00034670098,0.0003024519,0.000100009725,0.00006011995,0.00031853418,0.000079551064,0.000024515131],"category_scores_gemma":[0.00007486332,0.00020769543,0.00007559339,0.000621852,0.00021914925,0.00025680952,0.000045956684,0.00051199715,0.000008883068],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0039944854,0.00216304,0.50944626,0.00008170223,0.00006418437,0.0012110699,0.0034431953,0.0024936628,0.42524937,0.0008751966,0.000030830688,0.050946977],"study_design_scores_gemma":[0.008420154,0.003348878,0.8750713,0.00031939236,0.00012496587,0.00023620702,0.0004700896,0.044628516,0.05833511,0.00038333033,0.007973051,0.00068902696],"about_ca_topic_score_codex":0.000032053376,"about_ca_topic_score_gemma":0.000030922325,"teacher_disagreement_score":0.36691424,"about_ca_system_score_codex":0.00008582087,"about_ca_system_score_gemma":0.00020274108,"threshold_uncertainty_score":0.8469574},"labels":[],"label_agreement":null},{"id":"W2021662620","doi":"10.1016/j.bbalip.2012.12.009","title":"Autophagy: Emerging roles in lipid homeostasis and metabolic control","year":2012,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":140,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Lipid metabolism; Lipid droplet; Cell biology; Adipose tissue; Downregulation and upregulation; Homeostasis; Biology; Insulin resistance; White adipose tissue; Chemistry; Endocrinology; Insulin; Biochemistry; Apoptosis","score_opus":0.01597688813646713,"score_gpt":0.2978122632302937,"score_spread":0.28183537509382656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021662620","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23605461,0.7624697,0.000013193662,0.0001376233,0.00016584594,0.0007159662,0.00017344074,0.00004055779,0.0002290618],"genre_scores_gemma":[0.3529106,0.6460974,0.000090630776,0.0002885839,0.00024211449,0.00006777076,0.0002165125,0.00006540998,0.000020960611],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969612,0.0005286706,0.00088900054,0.0008063633,0.00018324862,0.00063151616],"domain_scores_gemma":[0.9982669,0.0001675964,0.00055157347,0.00063116715,0.000055205142,0.00032759554],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034497044,0.00080936024,0.003114718,0.0005152138,0.000068532216,0.00002232018,0.00026364956,0.000738824,0.00003702214],"category_scores_gemma":[0.000026992779,0.0006362803,0.0006896856,0.000392277,0.0005256676,0.0000725594,0.00016505897,0.0005798677,0.000010623683],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027841883,0.0009910407,0.00001960262,0.008559506,0.002093068,0.000038254584,0.0003540255,1.0851501e-7,0.24295223,0.0009266954,0.000047158414,0.7437399],"study_design_scores_gemma":[0.0069866288,0.001314756,0.0010380775,0.0045689098,0.013402078,0.00011580269,0.00011007089,0.00002701651,0.3594539,0.0002813565,0.6106375,0.00206393],"about_ca_topic_score_codex":0.000025542742,"about_ca_topic_score_gemma":0.0000010211049,"teacher_disagreement_score":0.741676,"about_ca_system_score_codex":0.000024209241,"about_ca_system_score_gemma":0.00022938814,"threshold_uncertainty_score":0.9996089},"labels":[],"label_agreement":null},{"id":"W2021804394","doi":"10.1016/j.radonc.2013.06.015","title":"The autophagy associated gene, ULK1, promotes tolerance to chronic and acute hypoxia","year":2013,"lang":"en","type":"article","venue":"Radiotherapy and Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto; University Health Network","funders":"KWF Kankerbestrijding","keywords":"Autophagy; Hypoxia (environmental); Gene knockdown; ULK1; Cancer research; Medicine; Head and neck squamous-cell carcinoma; Autophagy-related protein 13; Biology; Chemistry; Cell biology; Internal medicine; Apoptosis; Cancer; Protein kinase A; Head and neck cancer; Kinase; Cell cycle; Oxygen; Biochemistry; AMPK","score_opus":0.00896052342152508,"score_gpt":0.28781039633717737,"score_spread":0.2788498729156523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021804394","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96655035,0.022915663,0.00015316963,0.008717711,0.00020148285,0.00089853007,0.000006369607,0.000076189164,0.000480539],"genre_scores_gemma":[0.96916884,0.0145136835,0.0012413576,0.010463204,0.0005507023,0.0002773342,0.00000978925,0.0000460991,0.0037289874],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99891824,0.00009825667,0.00021278387,0.00028358525,0.000121076315,0.00036609164],"domain_scores_gemma":[0.99921334,0.00018818541,0.00007521612,0.00023072585,0.00005909967,0.00023345157],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019474664,0.00017583891,0.00037207056,0.000046160327,0.0002580076,0.000049218834,0.00010500955,0.00017205605,0.00022299148],"category_scores_gemma":[0.000026913072,0.000115560346,0.00005497734,0.00012543425,0.00018994987,0.00007072081,0.000022998614,0.0001634097,0.000023024846],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00084280816,0.0004760412,0.0046759066,0.0000427944,0.0016502788,0.00017248641,0.0022368587,0.0000064802157,0.3246827,0.0015016879,0.013056913,0.65065503],"study_design_scores_gemma":[0.010680754,0.008506643,0.6436469,0.00008382285,0.00024777162,0.0005612453,0.000088022614,0.0044392566,0.02442904,0.0023238412,0.30444488,0.0005478499],"about_ca_topic_score_codex":0.000039454855,"about_ca_topic_score_gemma":0.00003735185,"teacher_disagreement_score":0.6501072,"about_ca_system_score_codex":0.00027834903,"about_ca_system_score_gemma":0.00018426978,"threshold_uncertainty_score":0.4712414},"labels":[],"label_agreement":null},{"id":"W2021913838","doi":"10.1016/j.cjca.2013.07.650","title":"An Essential Role of Autophagy in Vascular Smooth Muscle Cell Homeostasis","year":2013,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Toronto Public Health","funders":"","keywords":"Autophagy; Vascular smooth muscle; Cell biology; Homeostasis; Medicine; Organelle; Oxidative stress; Cell; Restenosis; Cytoplasm; Hypoxia (environmental); Internal medicine; Smooth muscle; Biology; Biochemistry; Apoptosis; Chemistry","score_opus":0.005234547571985161,"score_gpt":0.22299569732311508,"score_spread":0.21776114975112992,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021913838","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916573,0.0052168244,0.00016323672,0.00013012836,0.00021997289,0.0001324753,0.000010922962,0.0000033588815,0.002465746],"genre_scores_gemma":[0.999008,0.00018453626,0.00013128684,0.00018050983,0.0004555063,0.0000036406734,0.0000064461215,0.00001683658,0.000013213667],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998972,0.00013675312,0.00036623908,0.00011347336,0.00011708187,0.00029445736],"domain_scores_gemma":[0.99876225,0.000024539719,0.0001394967,0.0002527742,0.00019217678,0.00062878133],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002170674,0.00010479337,0.0005280913,0.00039175223,0.000026691316,0.00000842814,0.0001628187,0.00013600996,0.00037485544],"category_scores_gemma":[0.000031295367,0.00009318446,0.0002431035,0.00014054982,0.000127457,0.000108840715,0.0000049237206,0.00020891393,0.00001555598],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043703782,0.0002756185,0.22464658,0.00028821657,0.0019647384,0.0047622053,0.0048431493,0.008589315,0.43688628,0.001170495,0.011641822,0.30449453],"study_design_scores_gemma":[0.0022631125,0.0006317433,0.958178,0.000039625626,0.00015008372,0.000075099604,0.00064135535,0.0000881565,0.0088399155,0.0012250071,0.027733933,0.00013396655],"about_ca_topic_score_codex":0.0035049575,"about_ca_topic_score_gemma":0.00043043346,"teacher_disagreement_score":0.7335314,"about_ca_system_score_codex":0.00008258272,"about_ca_system_score_gemma":0.0010607169,"threshold_uncertainty_score":0.5298471},"labels":[],"label_agreement":null},{"id":"W2022497376","doi":"10.1002/path.4090","title":"The autophagy protein <scp>LC3A</scp> correlates with hypoxia and is a prognostic marker of patient survival in clear cell ovarian cancer","year":2012,"lang":"en","type":"article","venue":"The Journal of Pathology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Vancouver General Hospital; University of Victoria; BC Cancer Agency; Simon Fraser University; Canadian Institutes of Health Research","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Serous fluid; Ovarian cancer; Hypoxia (environmental); Biology; Cancer research; Clear cell; Programmed cell death; Tumor hypoxia; Cell; Internal medicine; Cancer; Oncology; Pathology; Immunohistochemistry; Apoptosis; Medicine; Immunology; Radiation therapy; Chemistry","score_opus":0.008501553379664567,"score_gpt":0.2408275807758122,"score_spread":0.23232602739614763,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022497376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887943,0.0098020155,0.000026357679,0.000466804,0.00017517828,0.00040765863,0.000005036408,0.000004540291,0.00031806497],"genre_scores_gemma":[0.9985832,0.0006693569,0.00012983085,0.000254202,0.00010163806,0.00001369189,4.2385912e-7,0.00001946739,0.00022821137],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986803,0.00035845576,0.00037698427,0.00007607094,0.00022089086,0.00028729363],"domain_scores_gemma":[0.9987671,0.000404791,0.0004239693,0.00018301303,0.00011041317,0.00011070906],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00087259593,0.00012769311,0.00031085563,0.00006718753,0.00006793036,0.000005809488,0.00011483488,0.00008194811,0.0000397374],"category_scores_gemma":[0.00012407837,0.000059754297,0.000052930205,0.00012401663,0.0002473289,0.000062568,0.000036289923,0.0003605995,0.0000034224508],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0071184994,0.0021579075,0.8203207,0.00029756955,0.00076629187,0.0014982773,0.042623732,0.000062343235,0.1082898,0.0009717454,0.0011367592,0.014756357],"study_design_scores_gemma":[0.0034351929,0.0026375859,0.96652395,0.00026481904,0.00036811634,0.0013503364,0.0024890057,0.00008610902,0.020904452,0.000684308,0.0011895528,0.00006658354],"about_ca_topic_score_codex":0.000025759005,"about_ca_topic_score_gemma":0.0000099280205,"teacher_disagreement_score":0.14620323,"about_ca_system_score_codex":0.000026152777,"about_ca_system_score_gemma":0.00012767033,"threshold_uncertainty_score":0.24367094},"labels":[],"label_agreement":null},{"id":"W2022624659","doi":"10.1016/j.mib.2010.11.001","title":"Mechanisms and consequences of bacterial targeting by the autophagy pathway","year":2010,"lang":"en","type":"review","venue":"Current Opinion in Microbiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Cell biology; Diacylglycerol kinase; Cytosol; Signal transduction; Intracellular; Intracellular parasite; Bacteria; Microbiology; Protein kinase C; Biochemistry; Apoptosis; Genetics; Enzyme","score_opus":0.04804311534959795,"score_gpt":0.3585749887601489,"score_spread":0.310531873410551,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022624659","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00051994494,0.99198866,0.000024964125,0.000042010768,0.0061619794,0.0007651865,0.00046514344,0.000017119453,0.000014989696],"genre_scores_gemma":[0.000112351954,0.99748653,0.000089300855,0.000021370139,0.00029095213,0.00007609671,0.0018804877,0.000023235965,0.00001966459],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99835217,0.000307069,0.0006769972,0.00036634327,0.00004578882,0.0002516571],"domain_scores_gemma":[0.999,0.00021100868,0.0004367895,0.00025419026,0.00003855302,0.000059443337],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003578803,0.0003039019,0.0012327111,0.00010970808,0.000048150672,0.000009199172,0.00020778658,0.00043427665,0.00026697642],"category_scores_gemma":[0.00007165031,0.00018132704,0.0002039077,0.00011428296,0.0005038549,0.00002007101,0.00008755758,0.0006391584,0.000012824544],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004297208,0.00016931508,0.0000048356046,0.010016227,0.00011170496,0.000002323971,0.000111876965,1.19182415e-8,0.05922207,0.0019041753,0.003516804,0.9248977],"study_design_scores_gemma":[0.00050267176,0.000112187336,0.000002369192,0.004554261,0.000085401865,0.0001564804,0.000013853291,3.5464637e-7,0.0012663692,0.00025039632,0.99289674,0.0001589373],"about_ca_topic_score_codex":0.000005706512,"about_ca_topic_score_gemma":3.8341497e-7,"teacher_disagreement_score":0.98937994,"about_ca_system_score_codex":0.00002724457,"about_ca_system_score_gemma":0.00035787062,"threshold_uncertainty_score":0.7394302},"labels":[],"label_agreement":null},{"id":"W2024184215","doi":"10.2353/ajpath.2010.090594","title":"Autophagy Is a Renoprotective Mechanism During in Vitro Hypoxia and in Vivo Ischemia-Reperfusion Injury","year":2010,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":380,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Diabetes and Digestive and Kidney Diseases; School of Medicine; University of Pittsburgh; American Cancer Society; U.S. Department of Veterans Affairs; National Cancer Institute; National Institutes of Health","keywords":"Autophagy; Ischemia; ATG5; Reperfusion injury; Hypoxia (environmental); Programmed cell death; Apoptosis; Renal ischemia; Biology; Cell biology; Kidney; In vivo; Pharmacology; Medicine; Chemistry; Endocrinology; Internal medicine; Biochemistry","score_opus":0.003928242374664361,"score_gpt":0.2548755700180854,"score_spread":0.25094732764342104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024184215","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9989512,0.00015778896,0.0000452121,0.0004680589,0.00011952316,0.00013369044,0.0000052139844,0.00000886005,0.000110449786],"genre_scores_gemma":[0.99681437,0.0001709586,0.002100173,0.0007238937,0.00012068683,0.0000076111473,3.3454086e-7,0.000018672608,0.000043283388],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893934,0.00008926183,0.00039170778,0.00019881949,0.00014472195,0.00023613186],"domain_scores_gemma":[0.99926245,0.000043159493,0.00031291778,0.00017536669,0.00006545687,0.00014064695],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003284439,0.00013868803,0.0005088019,0.0003799217,0.000029931882,0.000005132902,0.00008866131,0.00009906811,0.00013187912],"category_scores_gemma":[0.000104603685,0.00011728371,0.00007310445,0.00023830213,0.00022703383,0.00007877491,0.000044351567,0.00075927266,0.0000025435916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018764486,0.00013335473,0.0013432312,0.0000095654295,0.000019295632,0.0028191537,0.001245671,2.392347e-7,0.9820459,0.00003067466,0.0000059451345,0.010470552],"study_design_scores_gemma":[0.0020001628,0.0008964548,0.024433937,0.000052980373,0.000024965506,0.0035795306,0.0004467897,0.000030701016,0.9669667,0.0014302045,0.000034136232,0.0001034553],"about_ca_topic_score_codex":0.000036506004,"about_ca_topic_score_gemma":0.0000059477807,"teacher_disagreement_score":0.023090707,"about_ca_system_score_codex":0.000047092057,"about_ca_system_score_gemma":0.00010593813,"threshold_uncertainty_score":0.4782691},"labels":[],"label_agreement":null},{"id":"W2024215142","doi":"10.1126/sageke.2005.5.re1","title":"Lipofuscin and Aging: A Matter of Toxic Waste","year":2005,"lang":"en","type":"review","venue":"Science of Aging Knowledge Environment","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":286,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Lipofuscin; Cell biology; Lysosome; Programmed cell death; Cell; Mitochondrion; Chemistry; Biology; Neuroscience; Biochemistry; Apoptosis","score_opus":0.026570365748933407,"score_gpt":0.3276886181732377,"score_spread":0.3011182524243043,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024215142","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0036236756,0.99342614,0.000016055481,0.00006423871,0.00011358142,0.00043609683,0.0000085098645,0.000010104104,0.0023015651],"genre_scores_gemma":[0.0065551763,0.99041986,0.0004872151,0.000029498531,0.0001602557,0.000020967937,0.0000046622526,0.000029770228,0.0022925746],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99819183,0.00004393779,0.00052606553,0.0005134666,0.0004112621,0.00031342657],"domain_scores_gemma":[0.9988225,0.000050902152,0.00031544067,0.0005900856,0.00001614316,0.00020490492],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004991229,0.0002914315,0.0010630386,0.00036692203,0.00006824413,0.000011615571,0.0003018345,0.00008564331,0.00040447307],"category_scores_gemma":[0.000012427958,0.00022117731,0.00022717436,0.0002901657,0.0011165641,0.00008946271,0.0002341154,0.00018289966,0.00014263741],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000026992682,0.00026271102,0.00007993293,0.00649034,0.00006847333,0.000006347237,0.00055203337,0.0000013159079,0.00032821685,0.000026302869,0.00012948884,0.99205214],"study_design_scores_gemma":[0.00073794776,0.00024866094,0.0007257595,0.024269303,0.0012641189,0.00008080373,0.00014260349,0.00005203391,0.004185334,0.000046833244,0.96774834,0.000498245],"about_ca_topic_score_codex":0.000001878633,"about_ca_topic_score_gemma":1.4630228e-7,"teacher_disagreement_score":0.9915539,"about_ca_system_score_codex":0.00017052636,"about_ca_system_score_gemma":0.00029334944,"threshold_uncertainty_score":0.90193486},"labels":[],"label_agreement":null},{"id":"W2024336151","doi":"10.1074/jbc.m706304200","title":"HspB8 Chaperone Activity toward Poly(Q)-containing Proteins Depends on Its Association with Bag3, a Stimulator of Macroautophagy","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":351,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"BAG3; Autophagy; Chaperone (clinical); Cell biology; Chemistry; Association (psychology); Biology; Medicine; Biochemistry; Psychology; Nursing","score_opus":0.03587014084229598,"score_gpt":0.3034991718633009,"score_spread":0.2676290310210049,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024336151","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99755514,0.0005268233,0.00033848252,0.00028548363,0.000038004204,0.00013028488,0.000009308681,0.000018891356,0.0010975691],"genre_scores_gemma":[0.9988354,0.000049735565,0.0003459962,0.00021486297,0.00035644733,0.0000023794926,0.0000038752564,0.000011119494,0.00018020021],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99871814,0.000028885504,0.00039861436,0.00015749336,0.00043152526,0.00026531977],"domain_scores_gemma":[0.99857044,0.00016640191,0.0006956642,0.000119694865,0.00022836872,0.0002194066],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006232427,0.00016343752,0.00048245143,0.000040295952,0.000037326423,0.000007436348,0.000111401416,0.0002795638,0.0002916591],"category_scores_gemma":[0.00035618703,0.000100392244,0.00017629493,0.00012456186,0.00004502499,0.000057710353,0.000020502288,0.00047520243,0.0000028563018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007179103,0.0007142553,0.027093915,0.00007363228,0.00029514066,0.0003278813,0.000083235565,0.00000486663,0.9570852,0.000011901942,0.00001091772,0.0071199466],"study_design_scores_gemma":[0.0024312483,0.0021232923,0.14275084,0.000149517,0.000062178275,0.00011564218,0.00006962338,0.000021242351,0.8520373,0.000024113291,0.00011757005,0.0000974172],"about_ca_topic_score_codex":0.0000024004898,"about_ca_topic_score_gemma":1.834409e-7,"teacher_disagreement_score":0.11565693,"about_ca_system_score_codex":0.00023135627,"about_ca_system_score_gemma":0.00013568296,"threshold_uncertainty_score":0.4093877},"labels":[],"label_agreement":null},{"id":"W2024889845","doi":"10.1097/mpg.0b013e3181617895","title":"Autophagy: Healthy Eating and Self‐digestion for Gastroenterologists","year":2008,"lang":"en","type":"review","venue":"Journal of Pediatric Gastroenterology and Nutrition","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Medicine; Mechanism (biology); Organelle; Cell biology; Bioinformatics; Computational biology; Biology; Biochemistry; Apoptosis","score_opus":0.028509132731483432,"score_gpt":0.33060261314899725,"score_spread":0.3020934804175138,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024889845","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.09339962,0.90474224,0.00045888664,0.00019928394,0.00031497295,0.00082142284,0.00003741062,0.000024316072,0.0000018639837],"genre_scores_gemma":[0.0026352603,0.99158144,0.0028651508,0.000323212,0.0024196738,0.00007002714,0.00006565839,0.000033516146,0.00000607009],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99799347,0.000211014,0.0009919979,0.0002765984,0.00016589694,0.00036101716],"domain_scores_gemma":[0.9980432,0.00017491641,0.0012214651,0.00011780462,0.00016672879,0.00027592617],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030221412,0.00032934477,0.0015783402,0.0005304932,0.00013906896,0.000014860519,0.00007856415,0.00034732305,0.0000051192906],"category_scores_gemma":[0.00007124482,0.00026386895,0.00044661068,0.000093587245,0.00008603786,0.00011782227,0.000028369024,0.0005317203,9.051958e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.03248244,0.012938864,0.11337808,0.18995015,0.0049825446,0.0025561876,0.0005904593,0.0000015300315,0.00001013884,0.000104755236,0.028025394,0.61497945],"study_design_scores_gemma":[0.052384432,0.12714483,0.055803202,0.01636865,0.024430834,0.1212255,0.0001021018,0.00010479773,0.0000036025237,0.0006604417,0.60090464,0.0008669625],"about_ca_topic_score_codex":7.2253414e-7,"about_ca_topic_score_gemma":4.3100218e-7,"teacher_disagreement_score":0.6141125,"about_ca_system_score_codex":0.00008830591,"about_ca_system_score_gemma":0.00014096645,"threshold_uncertainty_score":0.99998134},"labels":[],"label_agreement":null},{"id":"W2025922737","doi":"10.1038/ncomms4430","title":"HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress","year":2014,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University Health Network; University of Toronto; BC Cancer Agency; Canadian Heart Research Centre; Heart and Stroke Foundation; University of Ottawa","funders":"Canadian Institutes of Health Research; Ontario Ministry of Research and Innovation; Heart and Stroke Foundation of Canada","keywords":"Ubiquitin ligase; Ubiquitin; Cell biology; Heart failure; Chemistry; Autophagy; Protein degradation; Biology; Internal medicine; Biochemistry; Medicine","score_opus":0.016620238575960025,"score_gpt":0.3081514385848017,"score_spread":0.2915312000088417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025922737","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97906,0.0015621205,0.0012335834,0.0138477255,0.00009323155,0.003018912,0.000031380707,0.00014613227,0.0010068917],"genre_scores_gemma":[0.9947894,0.000052591586,0.0028981708,0.0003707057,0.000041752828,0.0009888804,0.00010995745,0.00002449279,0.00072402],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998588,0.0005524952,0.00022577713,0.00021953988,0.00024836266,0.0001658076],"domain_scores_gemma":[0.9979685,0.00011651717,0.00007500926,0.0015835199,0.0001510987,0.00010536685],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006345945,0.00012838728,0.00019544552,0.00025016346,0.00015553924,0.000027588725,0.00035098652,0.00023176913,0.000008278596],"category_scores_gemma":[0.00063768734,0.000119740165,0.000068169844,0.00039290098,0.00004888614,0.000105897154,0.00010878368,0.0007551895,0.00003522463],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0069113662,0.0026756069,0.022107407,0.00026152766,0.0002770248,0.000012319251,0.0024572003,0.00025188393,0.79014444,0.025219904,0.00071325974,0.14896806],"study_design_scores_gemma":[0.0050150994,0.0013403755,0.7851884,0.00150547,0.00021575345,0.00002150909,0.0009844294,0.0195442,0.09537011,0.0024871517,0.08737622,0.0009512947],"about_ca_topic_score_codex":0.00008570158,"about_ca_topic_score_gemma":0.00041674514,"teacher_disagreement_score":0.763081,"about_ca_system_score_codex":0.00021121293,"about_ca_system_score_gemma":0.00013216637,"threshold_uncertainty_score":0.48828623},"labels":[],"label_agreement":null},{"id":"W2026008461","doi":"10.4161/auto.21863","title":"Bacterial autophagy","year":2012,"lang":"hu","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Autophagy; Biology; Intracellular parasite; PI3K/AKT/mTOR pathway; Cell biology; Intracellular; Innate immune system; ULK1; Vacuole; Microbiology; Kinase; Biochemistry; Protein kinase A; Signal transduction; Immune system; Apoptosis; Immunology","score_opus":0.020017690342552286,"score_gpt":0.2932614479939045,"score_spread":0.2732437576513522,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026008461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9015427,0.045149323,0.00016183496,0.0005362195,0.015487942,0.0009886094,0.00015063662,0.0005471058,0.03543558],"genre_scores_gemma":[0.95726526,0.0011100977,0.00035639032,0.0027252599,0.013547818,0.000075198186,0.00021251719,0.0002057786,0.024501696],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9948107,0.000328283,0.0010065752,0.0007493012,0.00084860605,0.0022565592],"domain_scores_gemma":[0.9962522,0.00022695867,0.00036648242,0.0014222576,0.00014701135,0.0015851371],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0007239819,0.0008705394,0.0011489427,0.00029056994,0.00035204398,0.000115224146,0.0005071802,0.0007080155,0.043697935],"category_scores_gemma":[0.00019092564,0.0008273455,0.00064189296,0.00052372366,0.0003529554,0.000750106,0.00022795152,0.0007125476,0.01591045],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0061820033,0.01869808,0.023186002,0.002347299,0.008505067,0.0029051753,0.020931339,0.000015341824,0.32426986,0.10832873,0.18770668,0.2969244],"study_design_scores_gemma":[0.00865869,0.0008997982,0.26532355,0.00035927922,0.0014747694,0.00033573495,0.00033763627,0.0002751927,0.21409154,0.0006818962,0.50611794,0.0014439805],"about_ca_topic_score_codex":0.00010643867,"about_ca_topic_score_gemma":0.0000021163532,"teacher_disagreement_score":0.31841126,"about_ca_system_score_codex":0.00032391245,"about_ca_system_score_gemma":0.0005523481,"threshold_uncertainty_score":0.9994177},"labels":[],"label_agreement":null},{"id":"W2026198376","doi":"10.1371/journal.pone.0076503","title":"Induction of Autophagy Is an Early Response to Gefitinib and a Potential Therapeutic Target in Breast Cancer","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Simon Fraser University; University of British Columbia; Centre for Drug Research and Development; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Gefitinib; Autophagy; Breast cancer; Medicine; Oncology; Cancer research; Cancer; Biology; Bioinformatics; Internal medicine; Apoptosis; Genetics; Epidermal growth factor receptor","score_opus":0.031265577389951796,"score_gpt":0.27185720372217664,"score_spread":0.24059162633222486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026198376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954397,0.00045360468,0.0000070202605,0.0035075697,0.000024368122,0.00047394386,0.000037842117,0.000027618078,0.000028347387],"genre_scores_gemma":[0.99753314,0.000081144426,0.0003492724,0.001430725,0.000105430016,0.00009523289,0.000004337324,0.00001922549,0.000381515],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99918836,0.00007157278,0.00017297476,0.0001887058,0.00021612956,0.00016225528],"domain_scores_gemma":[0.9994994,0.000015637837,0.00004568979,0.00019167697,0.00009957061,0.00014805334],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001046144,0.000095547955,0.00022629864,0.00013888188,0.00002334332,0.000012005924,0.00004742957,0.000071913455,0.0012933282],"category_scores_gemma":[0.000009186493,0.00008445316,0.000025642206,0.00015318474,0.000041901236,0.00014306168,0.00001542934,0.00010262913,0.00002724276],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027713424,0.0014453736,0.027265776,0.000053774682,0.00019447839,0.000013082874,0.001749748,0.0000016360193,0.9611825,0.0000143678335,0.00003755461,0.0052703684],"study_design_scores_gemma":[0.0013488258,0.0004293805,0.8904772,0.00013533034,0.00007794182,0.0000069056273,0.00009848833,0.00021519327,0.10681459,0.00030425348,0.000009112205,0.000082787585],"about_ca_topic_score_codex":0.00065151765,"about_ca_topic_score_gemma":0.0000035175462,"teacher_disagreement_score":0.8632114,"about_ca_system_score_codex":0.00003207602,"about_ca_system_score_gemma":0.00007224974,"threshold_uncertainty_score":0.9996196},"labels":[],"label_agreement":null},{"id":"W2026398863","doi":"10.1016/j.cell.2009.01.054","title":"RETRACTED: VMA21 Deficiency Causes an Autophagic Myopathy by Compromising V-ATPase Activity and Lysosomal Acidification","year":2009,"lang":"en","type":"article","venue":"Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":60,"is_retracted":true,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"","keywords":"Autophagy; Biology; Myopathy; Cell biology; BAG3; Chaperone (clinical); Lysosome; Skeletal muscle; Cytoplasm; Biochemistry; Genetics; Apoptosis; Endocrinology; Enzyme","score_opus":0.014374115840325134,"score_gpt":0.27182273987456923,"score_spread":0.2574486240342441,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026398863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950829,0.00211986,0.00018834625,0.00023426709,0.00006522444,0.000240551,0.000013512852,0.0001370242,0.0019183145],"genre_scores_gemma":[0.99860716,0.00019532898,0.00018055695,0.00054361776,0.000101304366,0.000003869367,0.000055610853,0.000015647973,0.00029691376],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905384,0.000051791216,0.00015299753,0.00032658252,0.00019063598,0.00022415195],"domain_scores_gemma":[0.99928844,0.000025615736,0.000087594926,0.0003311355,0.000047028934,0.00022017652],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000092306276,0.00015515438,0.00020058815,0.00005922735,0.00013879793,0.00003827316,0.00006893741,0.0001275186,0.00007421306],"category_scores_gemma":[0.000017650163,0.0001417616,0.000044526267,0.00013426898,0.000061726256,0.00021766136,0.000008918208,0.00020115533,0.000022392029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001581401,0.0009615624,0.0013147735,0.00003592873,0.000005931454,0.000048767506,0.0003308283,8.453534e-7,0.9854753,0.000042872307,0.00022168507,0.011403349],"study_design_scores_gemma":[0.001292959,0.0005660372,0.38281405,0.000024817213,0.00007795605,0.000030193389,0.000062996296,0.00063588057,0.6137054,0.00024910606,0.00036348542,0.00017710248],"about_ca_topic_score_codex":0.000018219967,"about_ca_topic_score_gemma":7.4244286e-7,"teacher_disagreement_score":0.38149926,"about_ca_system_score_codex":0.000041810104,"about_ca_system_score_gemma":0.000060626364,"threshold_uncertainty_score":0.57808703},"labels":[],"label_agreement":null},{"id":"W2026414725","doi":"10.4161/auto.25955","title":"Autophagic flux and oxidative capacity of skeletal muscles during acute starvation","year":2013,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Christie (Canada); Université de Montréal; McGill University Health Centre","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Skeletal muscle; Oxidative phosphorylation; Internal medicine; Endocrinology; Citrate synthase; Cell biology; Biochemistry; Apoptosis; Medicine","score_opus":0.012093120533145646,"score_gpt":0.24755748139520692,"score_spread":0.23546436086206127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026414725","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99767405,0.0004283919,0.000079752775,0.00020124229,0.0000857249,0.00047832375,0.000020701478,0.000101865786,0.00092994067],"genre_scores_gemma":[0.997392,0.00009135052,0.00092825695,0.00023223147,0.00008561491,0.00004541688,0.000035534747,0.0000244189,0.0011651585],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99889785,0.00004189013,0.0003042619,0.00027061015,0.00023728854,0.00024807337],"domain_scores_gemma":[0.9992515,0.000047286714,0.00013902195,0.00028175238,0.00012466662,0.00015581051],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007605323,0.00018469342,0.00034370733,0.00012074605,0.000083404004,0.000017662818,0.000075293625,0.000101849044,0.001071725],"category_scores_gemma":[0.00003254444,0.0001593623,0.00009485091,0.00014698107,0.00018347452,0.00030118463,0.00004512575,0.00014407694,0.00009341757],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007606312,0.00024632874,0.0033755938,0.00018087572,0.00044637622,0.000050380302,0.0011822379,0.0000024564183,0.9852606,0.0015160671,0.00022132855,0.0074416795],"study_design_scores_gemma":[0.001314537,0.00017869864,0.6126685,0.000042473443,0.000079299556,0.000035989873,0.00009765605,0.0002826855,0.38340506,0.0016634136,0.00011727628,0.000114399845],"about_ca_topic_score_codex":0.00013534894,"about_ca_topic_score_gemma":0.0000022921065,"teacher_disagreement_score":0.6092929,"about_ca_system_score_codex":0.000042368356,"about_ca_system_score_gemma":0.0000527391,"threshold_uncertainty_score":0.99984145},"labels":[],"label_agreement":null},{"id":"W2026460725","doi":"10.4161/auto.21332","title":"Receptor protein complexes are in control of autophagy","year":2012,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences","keywords":"Biology; Autophagy; Cell biology; Context (archaeology); Scaffold protein; Receptor; ATG8; G protein-coupled receptor; Computational biology; Genetics; Signal transduction; Apoptosis","score_opus":0.015970119085370518,"score_gpt":0.2776413193798782,"score_spread":0.2616712002945077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026460725","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912892,0.0050672465,0.00022487667,0.00034476005,0.00022845136,0.0008862853,0.00004129229,0.000109611756,0.0018082729],"genre_scores_gemma":[0.99705446,0.000029618272,0.0005313543,0.00074279093,0.0002894482,0.000117328425,0.000022576498,0.0000398592,0.0011725437],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983368,0.000109723806,0.00048745752,0.00023410593,0.0003134652,0.00051846425],"domain_scores_gemma":[0.99894774,0.00007431654,0.00021812024,0.00043477738,0.000079318306,0.00024575452],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00030681593,0.00022369961,0.000625001,0.00018669199,0.000039369646,0.000006821968,0.00014223128,0.00014984823,0.0016586956],"category_scores_gemma":[0.000106068685,0.00019579798,0.00016663742,0.00028398764,0.00012963859,0.00017198273,0.000030091742,0.0002118961,0.00021731445],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001793218,0.004136251,0.13238117,0.00065372634,0.00048175617,0.00014926508,0.0017011096,0.000015711294,0.8199185,0.021724574,0.0022310584,0.014813628],"study_design_scores_gemma":[0.00607069,0.0002881174,0.550609,0.0002663449,0.000068110596,0.000023196935,0.00014590933,0.0001788661,0.43228108,0.0004747572,0.009347066,0.00024686084],"about_ca_topic_score_codex":0.000067332396,"about_ca_topic_score_gemma":0.000003916087,"teacher_disagreement_score":0.41822785,"about_ca_system_score_codex":0.00007944652,"about_ca_system_score_gemma":0.00009850533,"threshold_uncertainty_score":0.9992539},"labels":[],"label_agreement":null},{"id":"W2026988245","doi":"10.4161/cc.11.1.18669","title":"Autophagy is required for the activation of NFκB","year":2012,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Nautical Research Society","funders":"Ligue Contre le Cancer","keywords":"Autophagy; Cell biology; NF-κB; Chemistry; Biology; Signal transduction; Biochemistry; Apoptosis","score_opus":0.02508409426399046,"score_gpt":0.2986590758379714,"score_spread":0.27357498157398097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026988245","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904331,0.0014205743,0.0016220217,0.0005652821,0.0001694034,0.00037742566,0.000007090885,0.000027243861,0.0053778808],"genre_scores_gemma":[0.9964883,0.00004082212,0.00021695388,0.00093631493,0.0002617525,0.000030123387,0.000008623356,0.00001273253,0.0020044178],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995927,0.000008649743,0.00010448596,0.000064731976,0.000092260154,0.00013713757],"domain_scores_gemma":[0.9995428,0.00009207015,0.000057411078,0.00021895408,0.000035217538,0.000053574557],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010058314,0.00005447528,0.00009587791,0.000018645103,0.000049018734,0.0000026120745,0.00005120673,0.000040541563,0.00033922866],"category_scores_gemma":[0.000019030183,0.000035898072,0.00007967025,0.00005794412,0.000032287542,0.00006961611,0.000009341005,0.000035282457,0.000028975119],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011166702,0.0014990823,0.0057514743,0.00046105328,0.0003210378,0.000001578964,0.0067563658,0.000022242915,0.8860994,0.0038340816,0.03739785,0.05673915],"study_design_scores_gemma":[0.0010038733,0.00007832967,0.028077561,0.000014571675,0.00007372816,9.568548e-7,0.00013750157,0.00050440064,0.94655263,0.00055862026,0.0229513,0.000046548525],"about_ca_topic_score_codex":0.000009731167,"about_ca_topic_score_gemma":6.115715e-8,"teacher_disagreement_score":0.0604532,"about_ca_system_score_codex":0.000014897316,"about_ca_system_score_gemma":0.0000261581,"threshold_uncertainty_score":0.3714316},"labels":[],"label_agreement":null},{"id":"W2027236817","doi":"10.1089/ars.2008.2270","title":"Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment","year":2008,"lang":"en","type":"review","venue":"Antioxidants and Redox Signaling","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":762,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; University of Manitoba","funders":"","keywords":"Autophagy; Programmed cell death; Reactive oxygen species; Mitochondrial ROS; Cell biology; Cancer cell; Oxidative stress; Biology; Mitochondrion; Intracellular; Arsenic trioxide; Cell; Cancer; Apoptosis; Biochemistry","score_opus":0.054909446102867944,"score_gpt":0.3799133884492551,"score_spread":0.32500394234638713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027236817","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0105652,0.987209,0.0000912325,0.000070377544,0.000048237333,0.0015194581,0.0003828386,0.000026229907,0.00008741355],"genre_scores_gemma":[0.0061025647,0.9917869,0.00035351262,0.000016082855,0.00018060833,0.0002805558,0.00036590474,0.000039169026,0.0008747085],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989147,0.00003488354,0.0004186954,0.00035867578,0.0001021097,0.00017089622],"domain_scores_gemma":[0.9991145,0.000105905056,0.00040536703,0.00018482009,0.000091637725,0.00009773849],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000055577424,0.00027280487,0.0009953566,0.00010543231,0.00019211526,0.00001378291,0.00003975118,0.00019430174,0.000018901386],"category_scores_gemma":[0.000011137141,0.0001803157,0.00022065423,0.00011397687,0.00013238266,0.000056877816,0.00001605303,0.00006908816,3.325205e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000067936606,0.00018339089,0.0000712379,0.0022693742,0.0005673235,0.0000028375448,0.00014911755,2.0565359e-7,0.014902881,0.0002412521,0.000314997,0.9812294],"study_design_scores_gemma":[0.0016165607,0.0006071816,0.004357401,0.013253445,0.0019825026,0.000117624666,0.00003841274,0.000022890114,0.009512038,0.00024951468,0.9678772,0.00036519705],"about_ca_topic_score_codex":0.000021886328,"about_ca_topic_score_gemma":9.738575e-7,"teacher_disagreement_score":0.9808642,"about_ca_system_score_codex":0.000068301546,"about_ca_system_score_gemma":0.00018751736,"threshold_uncertainty_score":0.73530614},"labels":[],"label_agreement":null},{"id":"W2027823142","doi":"10.4161/auto.26740","title":"The role of Atg29 phosphorylation in PAS assembly","year":2013,"lang":"ms","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences","keywords":"Autophagy; Phosphorylation; Biology; Cell biology; Scaffold protein; Autophagy-related protein 13; Biochemistry; Protein phosphorylation; Signal transduction; Protein kinase A; Apoptosis","score_opus":0.007508239554322234,"score_gpt":0.24353094037174297,"score_spread":0.23602270081742074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027823142","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9360899,0.047109712,0.000018734268,0.0007353807,0.0005575584,0.00088417035,0.000008107268,0.000043104068,0.01455338],"genre_scores_gemma":[0.99371356,0.0022102823,0.00004183417,0.0004529917,0.00026255555,0.000103166734,0.000017042667,0.000042776308,0.0031557858],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9978507,0.00015890655,0.0006954045,0.00032329626,0.0004410828,0.0005305798],"domain_scores_gemma":[0.9983504,0.00035595757,0.0002875278,0.00068045926,0.0001587039,0.00016698646],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00038684986,0.00026458042,0.00043126382,0.000104462284,0.00013291383,0.000048887887,0.00029707712,0.0002332687,0.0014384453],"category_scores_gemma":[0.0001298527,0.00019250541,0.0001845758,0.00038444804,0.00018608673,0.00020026354,0.00006502694,0.00031691347,0.0009959952],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053815887,0.0014648435,0.04446796,0.00017364089,0.000627949,0.00008636595,0.0041675507,0.00006874706,0.1304091,0.039355073,0.002807643,0.77583295],"study_design_scores_gemma":[0.0026187277,0.00043223175,0.6761611,0.00025020362,0.00012870046,0.000007674078,0.0013525095,0.009203322,0.26917252,0.016275672,0.024103437,0.00029390433],"about_ca_topic_score_codex":0.0012782206,"about_ca_topic_score_gemma":0.00004512172,"teacher_disagreement_score":0.77553904,"about_ca_system_score_codex":0.00010894505,"about_ca_system_score_gemma":0.00024546764,"threshold_uncertainty_score":0.99978185},"labels":[],"label_agreement":null},{"id":"W2027893199","doi":"10.1038/cdd.2013.104","title":"p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene","year":2013,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; École Polytechnique Fédérale de Lausanne","keywords":"Autophagy; ATG5; Lipid metabolism; Cell biology; Transactivation; Biology; Autophagosome; Lipid droplet; Gene; Gene expression; Biochemistry","score_opus":0.013424558090315229,"score_gpt":0.21532429653617632,"score_spread":0.2018997384458611,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027893199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954784,0.0022021318,0.0013289714,0.00021812272,0.00009710301,0.0004144821,0.0000064559263,0.000020228968,0.00023409842],"genre_scores_gemma":[0.9983867,0.0004790307,0.0002540551,0.00022711985,0.00010599649,0.00002896907,0.00006469452,0.000010988028,0.00044245386],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9993518,0.000036513364,0.00017763303,0.00016293672,0.00016175245,0.00010933641],"domain_scores_gemma":[0.9996104,0.000021565273,0.00009067403,0.00014914195,0.00006688875,0.00006131226],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003515012,0.000113162845,0.00017254743,0.000033328535,0.00008838108,0.000020580328,0.000035218305,0.00007751615,0.00017563808],"category_scores_gemma":[0.000008727523,0.00007514114,0.000069216956,0.00006482441,0.00004829051,0.0001619394,0.000014037839,0.000064822896,0.0000029969733],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000075625685,0.00017707817,0.022635125,0.00013693365,0.00007034215,3.8598037e-7,0.0007135234,0.0000020994878,0.9705581,0.0034227918,0.000066573215,0.002141398],"study_design_scores_gemma":[0.00087238086,0.000026517257,0.5641755,0.000020909998,0.00009884129,0.0000024564592,0.000019977671,0.0017967897,0.42908254,0.0037054014,0.00014932772,0.00004936227],"about_ca_topic_score_codex":0.00005596381,"about_ca_topic_score_gemma":3.281964e-7,"teacher_disagreement_score":0.5415404,"about_ca_system_score_codex":0.000009923287,"about_ca_system_score_gemma":0.000024193347,"threshold_uncertainty_score":0.3064167},"labels":[],"label_agreement":null},{"id":"W2028205665","doi":"10.1111/imr.12288","title":"The cooperation between the autophagy machinery and the inflammasome to implement an appropriate innate immune response: do they regulate each other?","year":2015,"lang":"en","type":"review","venue":"Immunological Reviews","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; National Center for Advancing Translational Sciences; Science and Technology Development Fund; Cystic Fibrosis Foundation","keywords":"Autophagy; Biology; Inflammasome; Innate immune system; Endosome; Immune system; Cell biology; Lysosome; Phagosome; Mitophagy; Immunology; Intracellular; Inflammation; Genetics","score_opus":0.08427782229969806,"score_gpt":0.40337110186599145,"score_spread":0.3190932795662934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2028205665","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018553676,0.9859791,0.000024417677,0.0027570713,0.00022738043,0.00874741,0.00005587013,0.0000988906,0.00025449728],"genre_scores_gemma":[0.00057701493,0.99461985,0.000072422656,0.0008299372,0.00048280848,0.002026431,0.00013807675,0.00008698594,0.0011664663],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.98802114,0.007900158,0.0021501633,0.00074359134,0.0005185931,0.00066637],"domain_scores_gemma":[0.9946034,0.0014661542,0.00094315957,0.002561524,0.00018938191,0.00023637485],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.014716833,0.000876045,0.0033024268,0.000101490215,0.000894157,0.00032950361,0.0013232889,0.0004374602,0.000093063216],"category_scores_gemma":[0.0016399054,0.00028122068,0.0008079211,0.00049413985,0.00054376613,0.000107313965,0.00056569325,0.0013490372,0.0002838849],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011292355,0.0000486609,0.0000017333808,0.00046339334,0.00050616154,0.000011161407,0.00033341488,3.2281554e-7,0.000032154003,0.0026874205,0.00011566242,0.9946707],"study_design_scores_gemma":[0.0014326788,0.0005966292,0.0004576572,0.0025428329,0.0012198645,0.00006492762,0.000030830644,0.000004405835,0.000008071608,0.0016907802,0.9915933,0.00035799335],"about_ca_topic_score_codex":0.000048137645,"about_ca_topic_score_gemma":0.0000036601489,"teacher_disagreement_score":0.9943127,"about_ca_system_score_codex":0.00020464121,"about_ca_system_score_gemma":0.00036619915,"threshold_uncertainty_score":0.999964},"labels":[],"label_agreement":null},{"id":"W2028229212","doi":"10.1002/ijc.21547","title":"The pro‐cell death Bcl‐2 family member, BNIP3, is localized to the nucleus of human glial cells: Implications for glioblastoma multiforme tumor cell survival under hypoxia","year":2005,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Manitoba Health Research Council","keywords":"Programmed cell death; Cytoplasm; Nucleus; Cell biology; Biology; Mitochondrion; Cell; Downregulation and upregulation; Hypoxia (environmental); Apoptosis; Chemistry; Gene; Biochemistry","score_opus":0.033188951609447244,"score_gpt":0.3642579506776816,"score_spread":0.33106899906823434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2028229212","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9784681,0.0021662903,0.0026228833,0.013568754,0.0010504796,0.0006386266,0.00032717787,0.00001349169,0.0011441561],"genre_scores_gemma":[0.9926186,0.00038233813,0.000621373,0.0034332508,0.0015135739,0.00006443084,0.0000039061006,0.000032629818,0.0013298894],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984224,0.00003525916,0.00061450177,0.00014624267,0.0005689572,0.00021264145],"domain_scores_gemma":[0.99792796,0.00018358899,0.00048714952,0.00022863789,0.0010248908,0.0001477608],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002881175,0.00015536563,0.00024840873,0.000097308046,0.0001519641,0.000047201505,0.0005706969,0.00004677776,0.00017371206],"category_scores_gemma":[0.000022887947,0.00009140977,0.0003087208,0.00009458973,0.000077951416,0.00010292074,0.000046536712,0.00017805952,0.000014716518],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012784314,0.0023120928,0.0030267497,0.00010050755,0.0029657397,0.000032467346,0.0026363416,0.0047701006,0.85051984,0.0052476884,0.074809514,0.04079467],"study_design_scores_gemma":[0.012345312,0.0011495121,0.029864259,0.0002142953,0.00058494153,0.00006085619,0.0006449145,0.0014351105,0.42691237,0.002747647,0.52373296,0.00030780846],"about_ca_topic_score_codex":0.000076167,"about_ca_topic_score_gemma":0.00015391796,"teacher_disagreement_score":0.44892347,"about_ca_system_score_codex":0.00024556328,"about_ca_system_score_gemma":0.00036534423,"threshold_uncertainty_score":0.37275824},"labels":[],"label_agreement":null},{"id":"W2028725009","doi":"10.1016/j.cjca.2014.07.507","title":"ENDOTHELIAL AUTOPHAGY REGULATES CHOLESTEROL TRANSPORT AND IS A NOVEL REGULATOR OF ATHEROSCLEROSIS","year":2014,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Toronto Public Health","funders":"","keywords":"Autophagy; Transcytosis; Gene silencing; Cholesterol; Medicine; Endothelium; Cell biology; Endothelial dysfunction; In vivo; Endothelial stem cell; Intracellular; In vitro; Internal medicine; Biology; Apoptosis; Biochemistry; Endocytosis; Gene; Receptor","score_opus":0.012758389686971095,"score_gpt":0.22433904854262007,"score_spread":0.21158065885564897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2028725009","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966783,0.0005651677,0.0010866426,0.0005889503,0.0002408283,0.00009451775,0.00006124107,0.0000045598613,0.0006798067],"genre_scores_gemma":[0.99820274,0.0000795705,0.00021724885,0.0007232369,0.00060794584,0.0000016219185,0.0000025877491,0.00002063354,0.00014442755],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99909526,0.00004611833,0.00038348578,0.00013011809,0.00011163782,0.00023338242],"domain_scores_gemma":[0.9988649,0.00003962268,0.000185894,0.00020878956,0.00014835258,0.0005524743],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027371454,0.00012718458,0.00062873156,0.00019283583,0.000042552376,0.0000047850162,0.00010342354,0.00014956351,0.000048233593],"category_scores_gemma":[0.000041657746,0.00010643834,0.00023127144,0.000068773676,0.00027842863,0.000049923747,0.0000033865883,0.00014931265,0.0000016945879],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001061524,0.000056759083,0.62261426,0.00031752925,0.0030715917,0.0001492954,0.00371247,0.0003352788,0.33298317,0.0033122587,0.004555764,0.027830075],"study_design_scores_gemma":[0.003427875,0.00067144947,0.9313643,0.00012681531,0.00028237366,0.00071705214,0.00004283486,0.000029975967,0.021923387,0.00036901596,0.040932313,0.000112609974],"about_ca_topic_score_codex":0.00026309097,"about_ca_topic_score_gemma":0.00008704908,"teacher_disagreement_score":0.31105977,"about_ca_system_score_codex":0.000038192393,"about_ca_system_score_gemma":0.00045736862,"threshold_uncertainty_score":0.43404296},"labels":[],"label_agreement":null},{"id":"W2028984353","doi":"10.2337/db14-0267","title":"Adiponectin Stimulates Autophagy and Reduces Oxidative Stress to Enhance Insulin Sensitivity During High-Fat Diet Feeding in Mice","year":2014,"lang":"en","type":"article","venue":"Diabetes","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":223,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research","keywords":"Internal medicine; Endocrinology; Adiponectin; Insulin resistance; ATG5; Autophagy; Insulin; Oxidative stress; Skeletal muscle; Chemistry; Biology; Biochemistry; Medicine; Apoptosis","score_opus":0.006234449259948671,"score_gpt":0.2612132232259311,"score_spread":0.25497877396598245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2028984353","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981275,0.0007579608,0.000012848203,0.00044048045,0.00012903017,0.00030405744,0.000022556036,0.00009011143,0.000115454284],"genre_scores_gemma":[0.9988684,0.000045618788,0.00034884346,0.0003182006,0.00022903086,0.000029514196,0.000017993605,0.000027507509,0.000114862574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987327,0.00011427338,0.00021647893,0.000409757,0.00015669811,0.0003701331],"domain_scores_gemma":[0.99916464,0.00034704516,0.000071504764,0.00016835924,0.000059134818,0.0001892895],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024770992,0.00020527412,0.0004006898,0.0001584962,0.00008978534,0.00003215739,0.000055696346,0.00008333193,0.00003879132],"category_scores_gemma":[0.0003878976,0.0001918408,0.00003958551,0.00022414945,0.00006488253,0.00014321727,0.00007075374,0.00017612148,0.0000275954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026917818,0.0001559955,0.022482881,0.00012267366,0.000080984,0.000027087764,0.0011279259,0.000102132566,0.96775985,0.000040791576,0.000024362509,0.0078061577],"study_design_scores_gemma":[0.0006053006,0.00020937037,0.29440188,0.0003220489,0.000026606986,7.4579555e-7,0.000111646834,0.0008318513,0.7031601,0.00017142286,0.0000129563305,0.00014603918],"about_ca_topic_score_codex":0.00009987657,"about_ca_topic_score_gemma":0.00001792472,"teacher_disagreement_score":0.271919,"about_ca_system_score_codex":0.000049750306,"about_ca_system_score_gemma":0.000016081125,"threshold_uncertainty_score":0.78230405},"labels":[],"label_agreement":null},{"id":"W2029411138","doi":"10.4161/cc.10.10.15520","title":"Multiple pathways counteract cell death induced by RB1 loss: Implications for cancer","year":2011,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Biology; Autophagy; Myogenesis; Programmed cell death; Cell biology; Cancer cell; Apoptosis; Suppressor; Cancer research; Neoplastic transformation; Cancer; Myocyte; Genetics; Carcinogenesis","score_opus":0.05032834129676229,"score_gpt":0.29700349709324547,"score_spread":0.2466751557964832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029411138","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882925,0.0010520553,0.000493313,0.0001233658,0.00013925781,0.00059875636,0.0002945227,0.0000823431,0.008923844],"genre_scores_gemma":[0.9970187,0.00017128882,0.00032504342,0.001026402,0.00012546439,0.00033838546,0.00011979385,0.000040835548,0.00083410996],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99924004,0.000013717022,0.0001719722,0.000245329,0.00007595413,0.00025296884],"domain_scores_gemma":[0.99924487,0.00006517847,0.00008063406,0.0003527454,0.000083605904,0.00017297991],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000592079,0.00013667354,0.00017394878,0.000032311895,0.0001047272,0.000011272958,0.00011625502,0.00008387261,0.00045773777],"category_scores_gemma":[0.00001173426,0.00012178369,0.00010548652,0.00006396799,0.000022723792,0.000071239476,0.000016811875,0.000092539594,0.00008122715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036583192,0.0016778876,0.05615193,0.00015414508,0.0000826847,0.0000082927145,0.0017059178,0.0000022476638,0.924993,0.0002678697,0.010326608,0.004263594],"study_design_scores_gemma":[0.003925084,0.00028836244,0.078073986,0.00003768721,0.00016229208,0.0000031895652,0.00014516688,0.00057316676,0.8895044,0.0014546491,0.025538674,0.00029335852],"about_ca_topic_score_codex":0.00030289768,"about_ca_topic_score_gemma":0.000011845789,"teacher_disagreement_score":0.0354886,"about_ca_system_score_codex":0.000060475475,"about_ca_system_score_gemma":0.00010973806,"threshold_uncertainty_score":0.5011908},"labels":[],"label_agreement":null},{"id":"W2029590280","doi":"10.1002/ibd.23001","title":"Nutrient Modulation of Autophagy","year":2012,"lang":"en","type":"review","venue":"Inflammatory Bowel Diseases","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Autophagy; ATG16L1; Biology; Cell biology; Crosstalk; Nutrient sensing; NOD2; Paneth cell; Immune system; Genetics; Signal transduction; Small intestine; Biochemistry; Innate immune system; Apoptosis","score_opus":0.03416957718760274,"score_gpt":0.31984110955228523,"score_spread":0.2856715323646825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029590280","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018122519,0.9954943,0.000023093777,0.000004355082,0.00040864863,0.0012853352,0.00026707698,0.00016984214,0.0005351121],"genre_scores_gemma":[0.005274986,0.99251926,0.000030882027,0.000046239547,0.0007846981,0.00023767717,0.00056525256,0.00010640094,0.00043460864],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99768174,0.00013614752,0.00094566465,0.00036627232,0.00049876753,0.00037143595],"domain_scores_gemma":[0.99779093,0.00010608381,0.0006377321,0.00084594724,0.00011923308,0.00050006673],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001083607,0.0005086045,0.0015914402,0.00031382916,0.000059983322,0.000013555733,0.00019991062,0.0003273309,0.0007793597],"category_scores_gemma":[0.000053358537,0.000407533,0.0011679071,0.0001981867,0.00015062075,0.0001503459,0.0000695665,0.00021620841,0.0002755077],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015342758,0.00097016554,0.0010245056,0.07147297,0.0011208416,0.000249218,0.00007102778,0.000002435444,0.000005813703,0.0021904057,0.0006693463,0.92206985],"study_design_scores_gemma":[0.0007140441,0.00006620716,0.017923228,0.009720492,0.0056787003,0.000034531284,0.000007870353,0.000016361904,0.00001907409,0.0002620887,0.9651473,0.00041006375],"about_ca_topic_score_codex":0.0000022741228,"about_ca_topic_score_gemma":1.6269394e-7,"teacher_disagreement_score":0.964478,"about_ca_system_score_codex":0.00014734377,"about_ca_system_score_gemma":0.0007111469,"threshold_uncertainty_score":0.99983764},"labels":[],"label_agreement":null},{"id":"W2030257796","doi":"10.1038/embor.2009.265","title":"Opening a new DOR to autophagy","year":2009,"lang":"en","type":"letter","venue":"EMBO Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria; BC Cancer Agency","funders":"","keywords":"Autophagy; Regulator; Cell biology; Mitochondrion; Biology; Computational biology; Neuroscience; Biochemistry; Apoptosis; Gene","score_opus":0.020326229600064624,"score_gpt":0.30324128431633834,"score_spread":0.2829150547162737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030257796","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.015449738,0.0031050632,0.00031123986,0.88591325,0.002418851,0.0019909667,0.000009374743,0.0006273207,0.09017417],"genre_scores_gemma":[0.003425986,0.000023639179,0.0013566418,0.81792307,0.010524129,0.000037286365,0.0003180447,0.000102276244,0.16628893],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99725807,0.000033734326,0.0006788329,0.0007891868,0.0006867676,0.00055341696],"domain_scores_gemma":[0.9978666,0.000030800817,0.00032995755,0.0012590403,0.00008363822,0.00042998817],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016994611,0.0004370084,0.00084968447,0.00024189476,0.000073002826,0.00006534302,0.00014854563,0.0006569821,0.0026949032],"category_scores_gemma":[0.000115343624,0.00038310752,0.0003526825,0.00023297356,0.000021934893,0.00006646018,0.000060496117,0.0011202487,0.00038356142],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032892847,0.000030965715,0.00005747036,0.00005106862,0.0001437257,0.12257607,0.00011767862,0.0000018508376,0.00017705618,0.0000057068314,0.86586744,0.010938054],"study_design_scores_gemma":[0.0003953881,0.00024041858,0.0023186957,0.00041101102,0.0002461162,0.004670149,0.0000034615016,0.000002027003,0.0019025479,0.0011297034,0.9883026,0.00037786836],"about_ca_topic_score_codex":0.00012264388,"about_ca_topic_score_gemma":0.0000011979762,"teacher_disagreement_score":0.12243515,"about_ca_system_score_codex":0.00013268458,"about_ca_system_score_gemma":0.0008221185,"threshold_uncertainty_score":0.9998621},"labels":[],"label_agreement":null},{"id":"W2030430356","doi":"10.1038/mp.2013.174","title":"Autophagy has a key role in the pathophysiology of schizophrenia","year":2013,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":237,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; Victorian Brain Bank; Ben-Gurion University of the Negev; Tel Aviv University; University of Melbourne; National Health and Medical Research Council; State Government of Victoria; Canadian Friends of Tel Aviv University","keywords":"Autophagy; Schizophrenia (object-oriented programming); Neuroprotection; Hippocampal formation; Haploinsufficiency; Hippocampus; Clozapine; Programmed cell death; Neuroscience; Biology; Pathophysiology; Apoptosis; Medicine; Cell biology; Internal medicine; Endocrinology; Psychiatry; Phenotype; Genetics; Gene","score_opus":0.005829319480660527,"score_gpt":0.23458167598163202,"score_spread":0.22875235650097148,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030430356","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9886913,0.0051702624,0.00010696912,0.0033435847,0.0001906743,0.00044934894,0.0000032421897,0.000027073602,0.0020175916],"genre_scores_gemma":[0.9927891,0.000030656636,0.0017557123,0.005162273,0.00010246155,0.000083834435,0.000013795789,0.00002066925,0.000041515017],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990099,0.000114730545,0.0002569781,0.00020926703,0.00018882981,0.0002202958],"domain_scores_gemma":[0.9992659,0.000018694134,0.00007560904,0.0005356714,0.000039581704,0.000064564316],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009502781,0.00013931877,0.00025957858,0.00009364056,0.000037765152,0.000012543828,0.00019782336,0.00008709038,0.0003153749],"category_scores_gemma":[0.000016561138,0.00009507712,0.00016326956,0.00023518468,0.00010784556,0.000037079462,0.000024213265,0.00019939098,0.00013021797],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010874515,0.0034619025,0.02090697,0.00031363446,0.00045459697,0.00032181267,0.0024677454,0.00005998051,0.8893891,0.046479847,0.0093189385,0.025738027],"study_design_scores_gemma":[0.0074332105,0.0011306781,0.7393418,0.00018758557,0.00017335005,0.000101225276,0.00087251776,0.0007078729,0.029183043,0.21853733,0.0019312699,0.000400124],"about_ca_topic_score_codex":0.00010234183,"about_ca_topic_score_gemma":0.000005639548,"teacher_disagreement_score":0.86020607,"about_ca_system_score_codex":0.0000094180305,"about_ca_system_score_gemma":0.00015766174,"threshold_uncertainty_score":0.38771325},"labels":[],"label_agreement":null},{"id":"W2030667534","doi":"10.1074/jbc.m609532200","title":"Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1125,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; National Institutes of Health; Institute of Genetics; Wellcome Trust","keywords":"Autophagy; Huntingtin; Trehalose; Chemical chaperone; Cell biology; PI3K/AKT/mTOR pathway; Activator (genetics); Mutant; BAG3; Biochemistry; Huntingtin Protein; Chemistry; Biology; Alpha-synuclein; Apoptosis; Signal transduction; Parkinson's disease; Receptor","score_opus":0.018559921080947867,"score_gpt":0.261032360815052,"score_spread":0.24247243973410412,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030667534","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99475586,0.0036803752,0.000037064092,0.00038900384,0.000044707453,0.00007337204,0.000008893454,0.000011196443,0.0009995124],"genre_scores_gemma":[0.998574,0.00039150077,0.00023818013,0.00015235199,0.00044745667,0.0000022192173,0.0000025007068,0.000008488088,0.00018325885],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989203,0.00002070527,0.0005138935,0.0001446245,0.00022436454,0.0001760719],"domain_scores_gemma":[0.9990844,0.00011221873,0.00044311446,0.00014246788,0.00013066352,0.00008709578],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027355232,0.00013950383,0.00038580308,0.000017497472,0.000052332973,0.000016065444,0.0001582737,0.00015411476,0.00029850253],"category_scores_gemma":[0.00009988363,0.00007367091,0.00017587475,0.00009378091,0.0002089141,0.00003810179,0.000038648755,0.0003131908,0.00000154826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005235154,0.0003732593,0.0030584342,0.000049532337,0.000072940486,0.000058650054,0.000027823822,0.000004169452,0.9942051,0.0000413861,0.0000933612,0.0014918108],"study_design_scores_gemma":[0.0014814201,0.00023534168,0.110910594,0.00010294931,0.0000512611,0.00033580532,0.00007896974,0.000039425468,0.88546973,0.0003768451,0.000839261,0.00007839437],"about_ca_topic_score_codex":0.000008591081,"about_ca_topic_score_gemma":3.087941e-7,"teacher_disagreement_score":0.10873538,"about_ca_system_score_codex":0.000028087761,"about_ca_system_score_gemma":0.00006486399,"threshold_uncertainty_score":0.32683933},"labels":[],"label_agreement":null},{"id":"W2030739080","doi":"10.1042/bj20120972","title":"Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival","year":2012,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":149,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; National Institute for Health and Care Research; Natural Sciences and Engineering Research Council of Canada; Cancer Research UK","keywords":"Autophagy; ULK1; ATF4; Cancer research; Unfolded protein response; Cell biology; Hypoxia (environmental); Biology; Programmed cell death; Transcription factor; Protein kinase A; Endoplasmic reticulum; Kinase; Apoptosis; Chemistry; Genetics; Gene","score_opus":0.015768282810217363,"score_gpt":0.29544371610043785,"score_spread":0.2796754332902205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030739080","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9818569,0.014860986,0.001364239,0.0008895497,0.00053372746,0.00010478948,0.00006349257,0.0000106450925,0.00031567915],"genre_scores_gemma":[0.9978646,0.00024612463,0.00015365276,0.0005258589,0.00065780163,0.0000057605994,0.000034998076,0.000011484984,0.00049971306],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915326,0.000023664255,0.00024441778,0.00008011121,0.00027865404,0.00021987347],"domain_scores_gemma":[0.99937004,0.000028178336,0.000071615585,0.00007828597,0.00012890215,0.0003229631],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001554725,0.00009207135,0.00019200452,0.000029993083,0.00003830044,0.0000074632635,0.000062949584,0.00008591565,0.0013189556],"category_scores_gemma":[0.000020469617,0.0000740251,0.00012313374,0.000078444755,0.000041021754,0.00007332158,0.000007556427,0.00012311892,0.00001149752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004450072,0.00024502532,0.008979844,0.000017846616,0.00008094015,5.4176587e-7,0.00008975895,7.4743815e-7,0.9585378,0.00016628159,0.030751215,0.0006849987],"study_design_scores_gemma":[0.0017540717,0.000059809103,0.06681907,0.000056587116,0.00009813725,0.000016748449,0.00004758271,0.000009868998,0.9172503,0.00013455957,0.0136735095,0.00007979502],"about_ca_topic_score_codex":0.00001445896,"about_ca_topic_score_gemma":3.2143316e-7,"teacher_disagreement_score":0.05783923,"about_ca_system_score_codex":0.00009882816,"about_ca_system_score_gemma":0.00007742536,"threshold_uncertainty_score":0.999594},"labels":[],"label_agreement":null},{"id":"W2031869753","doi":"10.1097/fjc.0b013e31824cc427","title":"Autophagy in the Heart","year":2012,"lang":"en","type":"review","venue":"Journal of Cardiovascular Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; Programmed cell death; Mitochondrion; Mitophagy; Biology; Organelle; Lysosome; Cytosol; Catabolism; Homeostasis; Biochemistry; Apoptosis; Metabolism","score_opus":0.07236074504893368,"score_gpt":0.3966094706421347,"score_spread":0.324248725593201,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031869753","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00013898643,0.9965973,0.000029337954,0.00012681134,0.0018071155,0.00070480205,0.000003823832,0.000008545504,0.0005832943],"genre_scores_gemma":[0.0005909182,0.99385244,0.000063937405,0.001034227,0.004310077,0.0000429458,0.0000063187485,0.000048750728,0.000050410887],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963433,0.0014664291,0.0009681974,0.00017140938,0.00065776496,0.00039286827],"domain_scores_gemma":[0.998593,0.00024074026,0.00041948454,0.00043237556,0.00012275456,0.00019165073],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00296937,0.00033354506,0.003357813,0.00042092171,0.000038822483,0.000012314868,0.00040888705,0.0003300926,0.00037148714],"category_scores_gemma":[0.000028503759,0.00018613947,0.005837209,0.0003927672,0.0000895193,0.00008900004,0.000038445567,0.0013825247,0.00008445351],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007041331,0.00040847843,0.0000043751033,0.0045282054,0.015317709,0.003379886,0.000116410876,0.000011053282,0.0000051018105,0.000020752987,0.007511242,0.9686264],"study_design_scores_gemma":[0.0016076314,0.00015594793,0.000061826126,0.001026557,0.029189987,0.015885303,0.000013237259,7.059315e-7,0.000017647231,0.000013178034,0.9518888,0.00013919438],"about_ca_topic_score_codex":0.0000024815142,"about_ca_topic_score_gemma":5.7282197e-8,"teacher_disagreement_score":0.9684872,"about_ca_system_score_codex":0.00016827299,"about_ca_system_score_gemma":0.0006939022,"threshold_uncertainty_score":0.7590548},"labels":[],"label_agreement":null},{"id":"W2032352567","doi":"10.4161/auto.29639","title":"BCL2 and related prosurvival proteins require BAK1 and BAX to affect autophagy","year":2014,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Health and Medical Research Council; Canadian Institutes of Health Research; Australian Government","keywords":"Autophagy; BECN1; MCL1; Cell biology; Biology; Apoptosis; Programmed cell death; ATG8; Lipid-anchored protein; Endogeny; Downregulation and upregulation; Biochemistry; Gene","score_opus":0.0073954543397916255,"score_gpt":0.26586766898773034,"score_spread":0.25847221464793874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2032352567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9863845,0.0015756784,0.0003112248,0.0013849954,0.00031314214,0.0014869198,0.000011578718,0.00037333937,0.008158624],"genre_scores_gemma":[0.98963517,0.00006986789,0.00096785085,0.0015040842,0.00024880038,0.00013931665,0.000019686744,0.00007255625,0.0073426664],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99795496,0.00015234448,0.00037734816,0.0006709774,0.00033635012,0.0005080422],"domain_scores_gemma":[0.9985604,0.000118152704,0.000099438934,0.0005690168,0.0000727853,0.00058016664],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047374587,0.00034846875,0.0005650094,0.00017718475,0.00019263508,0.000059259022,0.00012216439,0.00023066004,0.00038673836],"category_scores_gemma":[0.0002469249,0.00029679338,0.000099649595,0.00029643028,0.00017152505,0.00020951177,0.0001248747,0.000269387,0.0001667158],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030607039,0.0018213154,0.017340023,0.002181161,0.001359607,0.0017609095,0.0070186956,0.000025727857,0.41682914,0.09447008,0.005465263,0.44866738],"study_design_scores_gemma":[0.012969703,0.0058448464,0.76698977,0.0006018966,0.00046551184,0.0010614234,0.00013128357,0.0039078128,0.14256288,0.012842597,0.051269613,0.0013526727],"about_ca_topic_score_codex":0.000054296695,"about_ca_topic_score_gemma":0.000006180033,"teacher_disagreement_score":0.7496497,"about_ca_system_score_codex":0.000048675192,"about_ca_system_score_gemma":0.00009384948,"threshold_uncertainty_score":0.99994844},"labels":[],"label_agreement":null},{"id":"W2034253809","doi":"10.1016/j.smim.2009.05.004","title":"Autophagy as an emerging dimension to adaptive and innate immunity","year":2009,"lang":"en","type":"review","venue":"Seminars in Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Foundation of Canada; Canadian Association of Gastroenterology; Crohn's and Colitis Foundation","keywords":"Autophagy; Innate immune system; Cell biology; Biology; Effector; Context (archaeology); Acquired immune system; Immune system; Vacuole; ATG16L1; Inflammasome; Cytoplasm; Immunology; Inflammation; Genetics; Apoptosis","score_opus":0.03094660960866409,"score_gpt":0.3639417768948446,"score_spread":0.3329951672861805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034253809","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.030191217,0.9673895,0.0000048264797,0.000070749586,0.00030029676,0.001007634,0.000010650906,0.000089781104,0.0009353366],"genre_scores_gemma":[0.0014269592,0.99657905,0.00045780346,0.0004916145,0.00007762928,0.0000923145,0.00014095297,0.000069327965,0.00066434056],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976069,0.0004462993,0.00064731156,0.0006206807,0.00015856326,0.0005202678],"domain_scores_gemma":[0.9985721,0.00014334125,0.00022281606,0.0008286418,0.000056075893,0.0001770419],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003703739,0.0005322266,0.0020039396,0.0007341601,0.00011140066,0.000013639502,0.00027386492,0.00065664935,0.00013030242],"category_scores_gemma":[0.00011995333,0.0004676042,0.00019949258,0.00055264373,0.00016611035,0.00009299775,0.00020916789,0.0010216982,0.000110331355],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026270375,0.00023545368,0.000003825565,0.00050443766,0.00023228781,0.00059439667,0.0006823465,2.8618626e-7,0.00009021929,0.00062544615,0.000075442666,0.99669313],"study_design_scores_gemma":[0.0013887214,0.0040107784,0.00075522566,0.025489537,0.0007631146,0.0013960236,0.00042744743,0.000012837395,0.00018713149,0.0017719894,0.96303505,0.0007621757],"about_ca_topic_score_codex":0.00012215177,"about_ca_topic_score_gemma":0.0000072729886,"teacher_disagreement_score":0.99593097,"about_ca_system_score_codex":0.00023518161,"about_ca_system_score_gemma":0.00032990993,"threshold_uncertainty_score":0.99977756},"labels":[],"label_agreement":null},{"id":"W2034517249","doi":"10.1016/j.mehy.2011.09.008","title":"De novo synthesis of phospholipids is coupled with autophagosome formation","year":2011,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"Phosphatidylethanolamine; Cell biology; Endoplasmic reticulum; Autophagy; Phosphatidylinositol; Autophagosome; Biology; Phosphatidylserine; Biogenesis; Phospholipid; Chemistry; Biochemistry; Phosphatidylcholine; Kinase; Membrane; Apoptosis","score_opus":0.031416196222378075,"score_gpt":0.2590525383426156,"score_spread":0.22763634212023753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034517249","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890349,0.0004843476,0.0017365107,0.00037509346,0.00004708848,0.00019430165,0.000009905539,0.000084080406,0.008033805],"genre_scores_gemma":[0.9960943,0.00020776712,0.0012083487,0.002047805,0.00008896131,0.00004629645,0.000002726975,0.000024495359,0.00027932195],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987207,0.000031816577,0.00026798667,0.00014760421,0.0005871637,0.00024472416],"domain_scores_gemma":[0.9990616,0.00018611139,0.00009329785,0.0002790088,0.00007433847,0.00030568178],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002391122,0.00013465951,0.00032944788,0.000075882475,0.000038595892,0.0000047725684,0.00014286216,0.00013007048,0.008197048],"category_scores_gemma":[0.00041303597,0.000089421555,0.000090959154,0.00015034857,0.00023639137,0.000093784154,0.000018982852,0.00012511994,0.00006004677],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02434303,0.017069584,0.177747,0.005607978,0.0052106604,0.0058524604,0.05000845,0.000005174805,0.035764348,0.021967154,0.008324777,0.64809936],"study_design_scores_gemma":[0.0038561241,0.001200721,0.115976505,0.0012184844,0.0005180748,0.0006092341,0.0006374981,0.0030874864,0.8671851,0.0021812064,0.0031680097,0.00036154126],"about_ca_topic_score_codex":0.00007117551,"about_ca_topic_score_gemma":0.0000027582155,"teacher_disagreement_score":0.8314208,"about_ca_system_score_codex":0.000035137804,"about_ca_system_score_gemma":0.0002481718,"threshold_uncertainty_score":0.9927096},"labels":[],"label_agreement":null},{"id":"W2034545147","doi":"10.1016/j.taap.2013.04.004","title":"High affinity capture and concentration of quinacrine in polymorphonuclear neutrophils via vacuolar ATPase-mediated ion trapping: Comparison with other peripheral blood leukocytes and implications for the distribution of cationic drugs","year":2013,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada","keywords":"Endosome; Bafilomycin; Pinocytosis; LAMP1; Intracellular; Phagosome; Acridine orange; Chemistry; Biochemistry; Percoll; ATPase; Endocytosis; Biology; Autophagy; Cell; In vitro; Apoptosis; Enzyme","score_opus":0.010752159666708748,"score_gpt":0.2691716431797636,"score_spread":0.2584194835130549,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034545147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99426615,0.0011698327,0.00034710357,0.0028971266,0.000029797422,0.001201363,0.00005497029,0.000014224874,0.000019408966],"genre_scores_gemma":[0.9987192,0.00026898863,0.000088054854,0.00049351034,0.000043026535,0.00026647403,0.00010536456,0.000009874037,0.0000054673455],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99933004,0.000050302875,0.00024383959,0.00018098642,0.000038187452,0.00015664294],"domain_scores_gemma":[0.99941087,0.00023021104,0.00015781262,0.00008110685,0.000057619727,0.00006235551],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009305821,0.00011511446,0.0003032739,0.000029457988,0.00009350832,0.0000044642916,0.000041661835,0.00012031175,0.00008451633],"category_scores_gemma":[0.0000051769443,0.00008370007,0.000017835764,0.00009672552,0.00040294733,0.000039864244,0.0000146199145,0.00013453567,3.3490858e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013970818,0.00052372494,0.013223862,0.00009157896,0.00022806444,4.6474483e-7,0.00081673026,0.00006673902,0.97635764,0.0059619625,0.00013805268,0.0011940909],"study_design_scores_gemma":[0.011554829,0.00088139507,0.72300184,0.00001473935,0.0006209337,0.00002968964,0.00045122355,0.0013219414,0.26091805,0.0008025732,0.00025418328,0.00014862009],"about_ca_topic_score_codex":0.000115493574,"about_ca_topic_score_gemma":0.000018332,"teacher_disagreement_score":0.7154396,"about_ca_system_score_codex":0.000019399005,"about_ca_system_score_gemma":0.00006170002,"threshold_uncertainty_score":0.341319},"labels":[],"label_agreement":null},{"id":"W2035163934","doi":"10.1371/journal.pone.0072263","title":"Autophagy Enhances Bacterial Clearance during P. aeruginosa Lung Infection","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; Izaak Walton Killam Health Centre; Beatrice Hunter Cancer Research Institute","funders":"Killam Trusts; Cystic Fibrosis Canada","keywords":"Autophagy; Pseudomonas aeruginosa; Cystic fibrosis; Biology; Microbiology; Intracellular parasite; In vivo; Immune system; Gene knockdown; Intracellular; Pathogen; Immunology; Cell biology; Bacteria; Apoptosis; Biochemistry","score_opus":0.016690791230074928,"score_gpt":0.23475717340236021,"score_spread":0.2180663821722853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035163934","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969192,0.00044370274,0.000015079791,0.00022818228,0.00014698881,0.00047834203,0.0000024203673,0.000215076,0.0015509976],"genre_scores_gemma":[0.99650675,0.0004147721,0.0002575601,0.00020099124,0.0008359295,0.0001084795,0.000013757927,0.000022985123,0.0016387922],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911934,0.000027677419,0.00017826684,0.00020720952,0.00023692835,0.00023058483],"domain_scores_gemma":[0.99949086,0.000017250426,0.00006250065,0.00022926759,0.00007578224,0.00012436793],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00003971857,0.00012390132,0.00024026267,0.000060523773,0.000090456764,0.0000324231,0.00004884315,0.00007506566,0.0040785964],"category_scores_gemma":[0.000034306177,0.000113706235,0.00006428791,0.00010536796,0.00004052419,0.00022898841,0.000020313091,0.00013449101,0.0007278255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020884513,0.0010373149,0.010513787,0.00030068596,0.00031869547,0.000014585756,0.00014359047,6.7603224e-7,0.98617864,0.00003477397,0.00016635342,0.0010820695],"study_design_scores_gemma":[0.0008682376,0.000084690444,0.41706264,0.00019441405,0.000088834626,0.000003666063,0.000004201743,0.0001828499,0.5812975,0.00006116355,0.00006341485,0.00008838965],"about_ca_topic_score_codex":0.00009219036,"about_ca_topic_score_gemma":0.0000026014418,"teacher_disagreement_score":0.40654886,"about_ca_system_score_codex":0.00005047869,"about_ca_system_score_gemma":0.000033889253,"threshold_uncertainty_score":0.99683183},"labels":[],"label_agreement":null},{"id":"W2035537270","doi":"10.1124/jpet.112.197590","title":"The Autophagy-Senescence Connection in Chemotherapy: Must Tumor Cells (Self) Eat Before They Sleep?","year":2012,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; National Cancer Institute; University of South Dakota; Virginia Commonwealth University; University of Minnesota","keywords":"Autophagy; Senescence; ATG5; Cell biology; Biology; Cancer research; Genetics; Apoptosis","score_opus":0.014786362323194885,"score_gpt":0.32624727125363234,"score_spread":0.31146090893043743,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035537270","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9799502,0.017060261,0.000015017376,0.0010034108,0.0015456869,0.00025482744,0.0000017154903,0.000018669954,0.00015020886],"genre_scores_gemma":[0.9910154,0.001904758,0.00014137026,0.0060876245,0.0007428846,0.000011027657,9.33656e-7,0.00002369967,0.00007231472],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99883926,0.0001329091,0.00039135813,0.00010794719,0.00018418908,0.0003443322],"domain_scores_gemma":[0.9993659,0.00009681576,0.00023836528,0.000093504146,0.000055239474,0.00015015731],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043400686,0.0001822148,0.0002895602,0.00008598315,0.00017802702,0.000017500279,0.00012294413,0.00009344162,0.00017153476],"category_scores_gemma":[0.000002298202,0.00011721215,0.000117346324,0.00009240491,0.00015283028,0.00018744683,0.0000242338,0.00035740781,0.000007698746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002145422,0.0014152922,0.008161057,0.000017652817,0.000507619,0.0000715347,0.0052515743,0.000005604801,0.9776319,0.00018044004,0.0003335649,0.0042783404],"study_design_scores_gemma":[0.005218287,0.0009500514,0.011685491,0.000023029757,0.00018610316,0.00058878236,0.0017354194,0.0003635827,0.96448106,0.00014030236,0.014500524,0.00012739011],"about_ca_topic_score_codex":0.0000037246832,"about_ca_topic_score_gemma":8.11369e-7,"teacher_disagreement_score":0.0151555035,"about_ca_system_score_codex":0.00014344895,"about_ca_system_score_gemma":0.00007399715,"threshold_uncertainty_score":0.47797728},"labels":[],"label_agreement":null},{"id":"W2036123648","doi":"10.1038/onc.2014.459","title":"IFNg-induced Irgm1 promotes tumorigenesis of melanoma via dual regulation of apoptosis and Bif-1-dependent autophagy","year":2015,"lang":"en","type":"article","venue":"Oncogene","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"National Science Foundation","keywords":"Autophagy; Biology; Gene knockdown; Cell biology; Carcinogenesis; Apoptosis; Programmed cell death; Melanoma; Cancer research; Cell growth; Cell; Biochemistry; Cancer; Genetics","score_opus":0.031638861286917216,"score_gpt":0.28402233471166066,"score_spread":0.25238347342474343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036123648","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973291,0.0011101055,0.00012965401,0.00013788757,0.00014243196,0.00033830406,0.000017850434,0.000036919268,0.000757756],"genre_scores_gemma":[0.9985606,0.000049539773,0.0007626751,0.00004511316,0.00014789322,0.000016984617,0.000030371195,0.00002633141,0.0003604667],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99878216,0.000057007866,0.00037453955,0.00023204679,0.00038997002,0.00016426056],"domain_scores_gemma":[0.9990234,0.000033642737,0.00021348397,0.00031953075,0.0002062454,0.00020374113],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025007938,0.00015260624,0.0004115614,0.00012832966,0.000027883028,0.0000047179606,0.000060793907,0.00010839865,0.00010670556],"category_scores_gemma":[0.000053671654,0.00013072838,0.00008246714,0.00017822521,0.00006428042,0.000068227724,0.000038783164,0.000053687072,0.000009421925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034965985,0.00033569415,0.0034549716,0.00009751587,0.000175657,0.00001358073,0.00048041032,0.0000041396543,0.9768586,0.00011522042,0.00006097568,0.01805356],"study_design_scores_gemma":[0.0020920795,0.00096227345,0.030921446,0.000059026792,0.00019994914,0.000043728844,0.00009977463,0.00022510756,0.96460885,0.00058595196,0.00008866366,0.00011316],"about_ca_topic_score_codex":0.00012074452,"about_ca_topic_score_gemma":0.000004128569,"teacher_disagreement_score":0.027466476,"about_ca_system_score_codex":0.000050588093,"about_ca_system_score_gemma":0.00018524958,"threshold_uncertainty_score":0.5330949},"labels":[],"label_agreement":null},{"id":"W2036222374","doi":"10.1038/onc.2009.49","title":"BNIP3 subfamily BH3-only proteins: mitochondrial stress sensors in normal and pathological functions","year":2008,"lang":"en","type":"review","venue":"Oncogene","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":218,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Cancer Institute; Manitoba Health Research Council","keywords":"Biology; Cell biology; Programmed cell death; Mitochondrion; Autophagy; Caenorhabditis elegans; Subfamily; Apoptosis; Gene; Genetics","score_opus":0.04037112288055856,"score_gpt":0.3239423136712172,"score_spread":0.2835711907906586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036222374","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.01972197,0.9763436,0.00001237992,0.00003772427,0.0004088459,0.0018320164,0.0002544916,0.000081492035,0.0013074956],"genre_scores_gemma":[0.00016244588,0.99560064,0.00044311647,0.00011466407,0.0012509656,0.00031128182,0.00046648562,0.00006683382,0.001583543],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99781454,0.00021957901,0.0006335548,0.00060948485,0.00031445667,0.000408418],"domain_scores_gemma":[0.9987591,0.000091163674,0.00020186786,0.0006191068,0.00005972032,0.00026903846],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007713867,0.000490521,0.0016320088,0.00024898737,0.000103185164,0.000018321769,0.00016749297,0.0006079506,0.00020531437],"category_scores_gemma":[0.0001232617,0.00036429326,0.00044282203,0.0003326986,0.00017332955,0.00005589522,0.00009980301,0.00061848934,0.00013784361],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024010915,0.0007919695,0.0002916364,0.003574556,0.00028349334,0.005044418,0.00010573052,0.0000011469186,0.00009547811,0.000025264952,0.0013232321,0.98822296],"study_design_scores_gemma":[0.0021090454,0.0005520874,0.0006856104,0.00496146,0.00064914324,0.0024743457,0.000035464273,0.0000029526511,0.00003870152,0.000017785287,0.98799837,0.00047504617],"about_ca_topic_score_codex":0.000031231037,"about_ca_topic_score_gemma":0.0000140859765,"teacher_disagreement_score":0.9877479,"about_ca_system_score_codex":0.00011938626,"about_ca_system_score_gemma":0.0006397433,"threshold_uncertainty_score":0.9998809},"labels":[],"label_agreement":null},{"id":"W2036822760","doi":"10.1139/o08-147","title":"A glycosylated antitumor ether lipid kills cells via paraptosis-like cell death","year":2009,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autophagy; ATG5; Vacuole; Programmed cell death; Cell biology; Apoptosis; Chinese hamster ovary cell; Chemistry; Biology; Caspase; Caspase 3; Biochemistry; Cytoplasm","score_opus":0.00709131270867,"score_gpt":0.24329420699854387,"score_spread":0.23620289428987387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036822760","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9818601,0.004318234,0.00008316235,0.00017629626,0.00014052338,0.00017631568,0.000023153616,0.000080855905,0.013141333],"genre_scores_gemma":[0.9928355,0.00093430287,0.00031303518,0.0020454552,0.00025954776,0.000007433174,0.00012036725,0.000015314086,0.0034690415],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988737,0.00003339071,0.00023049852,0.0004355655,0.00007021386,0.00035663985],"domain_scores_gemma":[0.9992554,0.000031570256,0.000092682276,0.00033788817,0.000041657433,0.00024077391],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000778843,0.00024952792,0.00032916368,0.000034004835,0.00007778833,0.000010713781,0.00010585028,0.0003498101,0.00042923662],"category_scores_gemma":[0.0000052194227,0.00020389946,0.00011488256,0.00009702032,0.00010651212,0.000019831465,0.000023465183,0.00019265739,0.00007012438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002872244,0.00037939704,0.0008918596,0.00006511522,0.00003304736,0.000047603993,0.00003832899,3.3052447e-7,0.9946033,0.000017812017,0.0008171736,0.0028188473],"study_design_scores_gemma":[0.001592839,0.00046047257,0.00093668146,0.000023868273,0.00008561389,0.00002651536,0.00002259155,0.000041983218,0.97744447,0.00022371653,0.01891061,0.00023063358],"about_ca_topic_score_codex":0.00000850917,"about_ca_topic_score_gemma":8.6398906e-8,"teacher_disagreement_score":0.018093435,"about_ca_system_score_codex":0.000018338047,"about_ca_system_score_gemma":0.00006652833,"threshold_uncertainty_score":0.8314779},"labels":[],"label_agreement":null},{"id":"W2037959286","doi":"10.4161/auto.18935","title":"A novel method for autophagy detection in primary cells","year":2012,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":158,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Parkinson's UK; National Institute for Health and Care Research; Natural Sciences and Engineering Research Council of Canada; Wellcome Trust","keywords":"Autophagy; Biology; Cell biology; Neurodegeneration; Primary cell; Organelle; Cell culture; Programmed cell death; Biochemistry; Apoptosis; Genetics; Pathology; Medicine","score_opus":0.020327559789240127,"score_gpt":0.3161299810193007,"score_spread":0.29580242123006056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037959286","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6827004,0.0032861033,0.30530792,0.00022708009,0.0016193013,0.0018838472,0.000042445743,0.00034991268,0.00458299],"genre_scores_gemma":[0.94327074,0.00004505222,0.050864715,0.0026073148,0.00069191225,0.00030719352,0.000036543115,0.0000700079,0.0021065106],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984151,0.000052393927,0.0003746498,0.0003188731,0.00022586816,0.00061308255],"domain_scores_gemma":[0.9990119,0.00019922483,0.00010630226,0.0003722703,0.000058634225,0.0002516736],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005545569,0.00023475374,0.00043322457,0.00022052694,0.000073697454,0.000013725442,0.00010612697,0.00020349499,0.00019591014],"category_scores_gemma":[0.00005588126,0.00021783604,0.00021595374,0.00029147472,0.000037086214,0.00022479912,0.000035077333,0.00020442644,0.000091419155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044169714,0.00091853435,0.00025275996,0.00016111018,0.000094014715,0.000014188531,0.00045133967,0.000013253791,0.9053263,0.0007584692,0.00027275967,0.09129556],"study_design_scores_gemma":[0.004974321,0.0002882537,0.11144112,0.00004567175,0.00013069256,0.00012326722,0.00004309836,0.002487988,0.8608743,0.00039233666,0.018930767,0.00026820812],"about_ca_topic_score_codex":0.00006540581,"about_ca_topic_score_gemma":0.000005577493,"teacher_disagreement_score":0.26057035,"about_ca_system_score_codex":0.00022042096,"about_ca_system_score_gemma":0.0001240545,"threshold_uncertainty_score":0.8883096},"labels":[],"label_agreement":null},{"id":"W2038272987","doi":"10.1038/onc.2009.487","title":"Involvement of JNK in the regulation of autophagic cell death","year":2010,"lang":"en","type":"article","venue":"Oncogene","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":178,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institut national de la recherche scientifique; National Institute of Biomedical Innovation; Uehara Memorial Foundation; Naito Foundation","keywords":"Autophagy; Programmed cell death; Cell biology; Biology; Apoptosis; Staurosporine; Kinase; Protein kinase A; Genetics","score_opus":0.01955116709809658,"score_gpt":0.28449013851305405,"score_spread":0.2649389714149575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038272987","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933938,0.00033419774,0.000024215115,0.00015897793,0.00006904066,0.00020225365,0.0000038240855,0.000005986108,0.005807754],"genre_scores_gemma":[0.99880445,0.00003592444,0.00057647435,0.00022280951,0.000066260334,0.000008722892,0.000015336082,0.000006243614,0.0002637802],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99945945,0.000023189645,0.00018547266,0.000078928126,0.00017825521,0.00007470066],"domain_scores_gemma":[0.9995487,0.000027811233,0.00008392733,0.00027387345,0.000039465864,0.000026234957],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020971436,0.000054348475,0.00012919396,0.000049884813,0.000011595485,0.0000013762957,0.00007598006,0.000046236342,0.00027035526],"category_scores_gemma":[0.000010061995,0.000035885118,0.000053044187,0.000109239474,0.00003441573,0.000018623774,0.000009781757,0.000077104756,0.0000060831608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006750183,0.00040649463,0.0121278325,0.000052063995,0.000014440854,0.000005742094,0.00066315336,0.0000064444484,0.98216164,0.0013510542,0.00009947643,0.0030441436],"study_design_scores_gemma":[0.0011531326,0.00016558696,0.24659185,0.000021940763,0.000038501348,0.0000029827606,0.00008518504,0.00017034706,0.74927235,0.0011939495,0.0012688978,0.00003530053],"about_ca_topic_score_codex":0.000046364705,"about_ca_topic_score_gemma":0.00001774375,"teacher_disagreement_score":0.23446402,"about_ca_system_score_codex":0.000009927655,"about_ca_system_score_gemma":0.00006625971,"threshold_uncertainty_score":0.29602006},"labels":[],"label_agreement":null},{"id":"W2038548965","doi":"10.1158/1538-7445.chtme14-a54","title":"Abstract A54: Pantoprazole enhances the activity of docetaxel chemotherapy for solid tumors by inhibition of autophagy","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children; Princess Margaret Cancer Centre","funders":"","keywords":"Autophagy; Docetaxel; Cancer cell; Cytotoxicity; In vivo; Pharmacology; Apoptosis; Cancer research; Transfection; In vitro; Chemistry; Cancer; Cell culture; Biology; Biochemistry","score_opus":0.09357294206208051,"score_gpt":0.447807592584549,"score_spread":0.3542346505224685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038548965","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939476,0.0027259132,0.000102012295,0.001501754,0.0000699768,0.0007788446,0.00010395525,0.00001677344,0.00075316225],"genre_scores_gemma":[0.99799293,0.0007533777,0.00002812591,0.00013160116,0.0001965226,0.00024410228,0.000014445099,0.00002257573,0.000616309],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99854445,0.000064277876,0.00023692526,0.00020469297,0.0006348252,0.00031480106],"domain_scores_gemma":[0.99870545,0.00018142199,0.00013838481,0.00031909492,0.00051399844,0.00014166065],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010156069,0.000105521896,0.00030932235,0.00008250937,0.00007410841,0.0000106938105,0.00015013057,0.00007395006,0.00023913947],"category_scores_gemma":[0.00010740123,0.00007097358,0.000105885854,0.00024707417,0.00038180372,0.000102087135,0.00002564941,0.00022841927,0.0000053159074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016769483,0.00035607896,0.00015026791,0.00023587488,0.000102005215,0.0000030417152,0.00070340367,0.0000057826946,0.9703117,0.00010854532,0.01094483,0.015401528],"study_design_scores_gemma":[0.002212583,0.00041895185,0.0070223855,0.00014927839,0.000015380905,0.0000014839461,0.0002796971,0.00006959437,0.9857416,0.0010895324,0.002935425,0.000064093394],"about_ca_topic_score_codex":0.00044507385,"about_ca_topic_score_gemma":0.00001502637,"teacher_disagreement_score":0.015429902,"about_ca_system_score_codex":0.00010581587,"about_ca_system_score_gemma":0.000676424,"threshold_uncertainty_score":0.2894219},"labels":[],"label_agreement":null},{"id":"W2038960341","doi":"10.1016/j.lfs.2014.06.016","title":"Stimulation of autophagic activity in human glioma cells by anti-proliferative ardipusilloside I isolated from Ardisia pusilla","year":2014,"lang":"en","type":"article","venue":"Life Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Natural Science Foundation of China","keywords":"Autophagy; Glioma; Cell cycle; Apoptosis; Biology; Cell biology; Flow cytometry; Cell growth; Cell cycle checkpoint; Cancer cell; Cell; Immunocytochemistry; Cell culture; Programmed cell death; Cancer research; Molecular biology; Cancer; Biochemistry","score_opus":0.016003118477548053,"score_gpt":0.3011582469383726,"score_spread":0.2851551284608246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038960341","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970829,0.00032450177,0.0006567751,0.00017675954,0.0001423687,0.00027879176,0.000027282034,0.00004548631,0.001265166],"genre_scores_gemma":[0.9993722,0.000016121941,0.00017513348,0.00026564076,0.00009585657,0.000006808246,0.000015179105,0.00000907973,0.000043971635],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99848825,0.00015420586,0.00029864284,0.00038574924,0.00043535433,0.00023779242],"domain_scores_gemma":[0.99924964,0.00013360976,0.00018196767,0.00023526412,0.000055456694,0.00014404519],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039122245,0.00015671135,0.00041670108,0.00017401292,0.0001472967,0.000024595098,0.00016406908,0.000093077084,0.00018364229],"category_scores_gemma":[0.00007163053,0.0001249156,0.00008491798,0.000504374,0.00035503347,0.00023975396,0.000034626133,0.00011703117,0.000021956801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012075469,0.00024451088,0.07147414,0.000016108179,0.000043214786,0.000008510675,0.00050309574,0.00057578913,0.92582,0.0001489839,0.00027205548,0.00077287364],"study_design_scores_gemma":[0.0013376535,0.00041601292,0.41558808,0.000065619606,0.000038236478,0.0000010949329,0.000090964735,0.023148676,0.55792916,0.0011639716,0.00006876225,0.00015173691],"about_ca_topic_score_codex":0.0003735211,"about_ca_topic_score_gemma":0.000008999228,"teacher_disagreement_score":0.36789078,"about_ca_system_score_codex":0.000025517616,"about_ca_system_score_gemma":0.00010227093,"threshold_uncertainty_score":0.50939107},"labels":[],"label_agreement":null},{"id":"W2039190533","doi":"10.6000/1929-2279.2015.04.01.1","title":"Autophagy in Cancer Therapy: Progress and Issues","year":2015,"lang":"en","type":"article","venue":"Journal of cancer research updates","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autophagy; Context (archaeology); Carcinogenesis; Cancer therapy; Biology; Cancer; Cancer treatment; Cancer research; Cell biology; Computational biology; Bioinformatics; Biochemistry; Genetics; Apoptosis","score_opus":0.16323396787361386,"score_gpt":0.5261894221731268,"score_spread":0.3629554542995129,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039190533","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7369469,0.2524958,5.734969e-7,0.01008504,0.000112168476,0.00018025216,0.0000041522217,0.00000670247,0.00016846623],"genre_scores_gemma":[0.93993866,0.058126293,0.00014218276,0.00033504813,0.0006866371,0.000044801098,0.0000011082094,0.000020912912,0.0007043606],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982456,0.0001523942,0.00030264523,0.00013482234,0.0008360366,0.00032849715],"domain_scores_gemma":[0.99863094,0.000052352443,0.000108869855,0.00013869612,0.0007070831,0.00036205546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012444184,0.00010342607,0.00032791428,0.00034781257,0.00003989307,0.00005066729,0.00015179008,0.0000642835,0.00033688362],"category_scores_gemma":[0.00007987905,0.000069219,0.000051178682,0.00034784505,0.0002449433,0.00022039356,0.000040086226,0.0004775827,0.0000046298633],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008561045,0.0010599947,0.56203467,0.00019454802,0.0007393826,0.001625168,0.0048673362,0.00003474952,0.009260519,0.0004918789,0.05803307,0.35309765],"study_design_scores_gemma":[0.016881414,0.0036589769,0.39299634,0.0015457983,0.00006820644,0.00019491605,0.0017348977,0.00029040282,0.15453444,0.008929522,0.41883355,0.00033152915],"about_ca_topic_score_codex":0.00051103515,"about_ca_topic_score_gemma":0.00007369064,"teacher_disagreement_score":0.3608005,"about_ca_system_score_codex":0.00019272373,"about_ca_system_score_gemma":0.0010037767,"threshold_uncertainty_score":0.36886394},"labels":[],"label_agreement":null},{"id":"W2039594437","doi":"10.4161/auto.27225","title":"Selective inhibition of IFNG-induced autophagy by <i>Mir155</i> - and <i>Mir31</i> -responsive WNT5A and SHH signaling","year":2013,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Versus Arthritis; Indian Council of Medical Research; Beijing Advanced Innovation Center for Structural Biology, Tsinghua University; Indian Institute of Science","keywords":"Autophagy; Biology; Cell biology; PI3K/AKT/mTOR pathway; Wnt signaling pathway; Signal transduction; BECN1; Intracellular parasite; Intracellular; Biochemistry; Apoptosis","score_opus":0.0069829890692910054,"score_gpt":0.24013738849785218,"score_spread":0.23315439942856117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039594437","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99288404,0.0039981385,0.00008610381,0.00046110962,0.00010037937,0.0009199705,0.00003555405,0.00013391081,0.0013807795],"genre_scores_gemma":[0.9963416,0.00021501965,0.00032161947,0.002111333,0.00011013171,0.00011482599,0.000047160862,0.000056089084,0.00068224675],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998068,0.00013014086,0.00048790828,0.0005420574,0.0003426573,0.00042928892],"domain_scores_gemma":[0.99854606,0.0003108121,0.00023032898,0.00030881385,0.0002695205,0.0003344531],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020738978,0.0003440548,0.0006101634,0.00018534304,0.00014487484,0.000045290144,0.00007338072,0.0002417038,0.0003832253],"category_scores_gemma":[0.00013499144,0.0003151059,0.000108454835,0.0003157688,0.00023068693,0.00034402532,0.00007401714,0.00029253692,0.00004558883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027090014,0.00023697052,0.0006912987,0.00012388224,0.00020364807,0.000058855967,0.00088105083,0.000001031488,0.9871742,0.0006748463,0.0032944526,0.006388861],"study_design_scores_gemma":[0.0035069634,0.00091758656,0.024863113,0.00016651582,0.00016423468,0.00012482573,0.00032826385,0.00031084876,0.9661557,0.002700709,0.00043757152,0.00032368026],"about_ca_topic_score_codex":0.00017636654,"about_ca_topic_score_gemma":0.000001915803,"teacher_disagreement_score":0.024171814,"about_ca_system_score_codex":0.000048664493,"about_ca_system_score_gemma":0.00015184525,"threshold_uncertainty_score":0.9999301},"labels":[],"label_agreement":null},{"id":"W2040389288","doi":"10.4161/auto.28979","title":"BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization","year":2014,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Windsor; Canadian Nautical Research Society","funders":"Ligue Contre le Cancer; Fonds National de la Recherche Luxembourg; Institut National de la Santé et de la Recherche Médicale","keywords":"Biology; Cytoplasm; Autophagy; Cell biology; Acetylation; Mutant; ATG5; Nucleus; Genetics; Gene","score_opus":0.005608867118635205,"score_gpt":0.23963027508183485,"score_spread":0.23402140796319965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040389288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9316349,0.0042498917,0.05618835,0.0005626317,0.00070171134,0.0007004984,0.000014324898,0.00078953285,0.0051581454],"genre_scores_gemma":[0.9927735,0.00012857944,0.00067883474,0.0022143847,0.0005622225,0.000041140003,0.00022131727,0.00011004001,0.0032699998],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975052,0.00018612623,0.00052926515,0.0006543425,0.00048480748,0.0006402758],"domain_scores_gemma":[0.9983836,0.00018605209,0.00020615212,0.0007233424,0.00012722319,0.0003736582],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00046777973,0.00041409984,0.0005976105,0.00017476694,0.00026640456,0.000069417656,0.0002225162,0.0002997597,0.0012550869],"category_scores_gemma":[0.00023963541,0.00038354087,0.0002271743,0.00041843287,0.000136103,0.00022825085,0.00006751916,0.00032483577,0.00051091175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007393542,0.002669775,0.009707292,0.001065292,0.0012795138,0.0005394667,0.002280356,0.0027135124,0.6367376,0.016630754,0.04750352,0.27813357],"study_design_scores_gemma":[0.004444185,0.00079035875,0.014042842,0.00021515923,0.00031882702,0.00012681408,0.00008600913,0.13439332,0.77525645,0.003315502,0.06625145,0.0007590497],"about_ca_topic_score_codex":0.000074976626,"about_ca_topic_score_gemma":0.0000021926007,"teacher_disagreement_score":0.27737454,"about_ca_system_score_codex":0.00011932031,"about_ca_system_score_gemma":0.00008719024,"threshold_uncertainty_score":0.99986166},"labels":[],"label_agreement":null},{"id":"W2040537103","doi":"10.1152/ajpcell.00357.2009","title":"Polyploidy impairs human aortic endothelial cell function and is prevented by nicotinamide phosphoribosyltransferase","year":2009,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; London Health Sciences Centre; Western University","funders":"Canadian Institutes of Health Research","keywords":"Sirtuin 1; Nicotinamide phosphoribosyltransferase; Cell biology; Biology; Senescence; Endothelial stem cell; Matrigel; Endothelial dysfunction; Cell; NAD+ kinase; Genetics; Gene; Biochemistry; Endocrinology; Downregulation and upregulation; Enzyme","score_opus":0.003965026205630513,"score_gpt":0.24186193657238686,"score_spread":0.23789691036675634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040537103","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99744296,0.0013080632,0.00007524944,0.0004982516,0.00018443108,0.00024473938,0.00003503775,0.000040942654,0.00017030242],"genre_scores_gemma":[0.99382925,0.00074704335,0.00011392273,0.0045655584,0.00042750803,0.0000057177112,0.000043101543,0.000038599508,0.00022926909],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99789596,0.000240928,0.0007002079,0.0004370553,0.00020177275,0.000524056],"domain_scores_gemma":[0.99837387,0.000096669406,0.0006588792,0.00035961726,0.0001466517,0.00036430577],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013971142,0.0003809534,0.0010556645,0.00015904944,0.00014740121,0.0000090279855,0.00020556753,0.00012548093,0.0003727434],"category_scores_gemma":[0.000012376842,0.00030930364,0.00037419793,0.00023758714,0.00057262054,0.00012470793,0.000023590634,0.00056278514,0.000021672693],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030471173,0.0013801283,0.00029541008,0.000036902664,0.00020016801,0.000009661971,0.00023191233,0.000007492437,0.9887953,0.000024143217,0.002957762,0.0030140076],"study_design_scores_gemma":[0.009381682,0.032860134,0.21609369,0.00008242833,0.0007362591,0.000107821594,0.0006523703,0.00007381117,0.73144925,0.0068382556,0.0011947103,0.00052956236],"about_ca_topic_score_codex":0.0000566769,"about_ca_topic_score_gemma":3.8902482e-7,"teacher_disagreement_score":0.25734603,"about_ca_system_score_codex":0.00006119991,"about_ca_system_score_gemma":0.00013016508,"threshold_uncertainty_score":0.9999359},"labels":[],"label_agreement":null},{"id":"W2040778960","doi":"10.1007/s00018-012-1032-3","title":"Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and aging","year":2012,"lang":"en","type":"review","venue":"Cellular and Molecular Life Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; National Institute for Health and Care Research; Lady Tata Memorial Trust; Natural Sciences and Engineering Research Council of Canada; Wellcome Trust","keywords":"Autophagy; Cell biology; Stem cell; Biology; Embryonic stem cell; Haematopoiesis; Mesenchymal stem cell; Cellular differentiation; Organelle; Apoptosis; Genetics","score_opus":0.032237206449589696,"score_gpt":0.2976917260897997,"score_spread":0.26545451964021,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040778960","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.017102135,0.98102385,0.00022158322,0.00006550771,0.00016144942,0.0007019255,0.00000490388,0.000032524484,0.00068614824],"genre_scores_gemma":[0.06332555,0.9356048,0.000118600685,0.0002322871,0.00015568615,0.000054151704,0.000056449786,0.0000311187,0.00042135228],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980652,0.00018429858,0.00047228363,0.0005601885,0.0003492813,0.00036879105],"domain_scores_gemma":[0.99910843,0.000040830295,0.00021497004,0.0002597014,0.000039694118,0.000336366],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004247089,0.0003529816,0.00088125555,0.0003144684,0.00018980764,0.000095972944,0.0001515236,0.00019798419,0.000044600416],"category_scores_gemma":[0.000014780544,0.00025737935,0.00014684846,0.0003805541,0.0002380636,0.00014040194,0.000083183535,0.00021610061,0.000011212072],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003387744,0.0008225317,0.0032171188,0.034279007,0.000423877,0.00045217245,0.001837005,0.000003206378,0.004623473,0.003804852,0.00024292797,0.9502599],"study_design_scores_gemma":[0.0022121887,0.0004562998,0.0006403098,0.008195507,0.0031530433,0.00015076442,0.00019708052,0.0002822424,0.014715801,0.0004934387,0.96793693,0.0015664136],"about_ca_topic_score_codex":0.000008850299,"about_ca_topic_score_gemma":0.00000145706,"teacher_disagreement_score":0.967694,"about_ca_system_score_codex":0.000030254558,"about_ca_system_score_gemma":0.00044410597,"threshold_uncertainty_score":0.99998784},"labels":[],"label_agreement":null},{"id":"W2040894660","doi":"10.1007/s00109-014-1132-7","title":"Defective autophagy impairs ATF3 activity and worsens lung injury during endotoxemia","year":2014,"lang":"en","type":"article","venue":"Journal of Molecular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"Instituto de Salud Carlos III; Fundación para el Fomento en Asturias de la Investigación Científica Aplicada y la Tecnología; Universidad de Oviedo","keywords":"Autophagy; Molecular medicine; Lung; Medicine; ATF3; Immunology; Biology; Internal medicine; Apoptosis; Cell cycle; Biochemistry","score_opus":0.00433417925081812,"score_gpt":0.27156790692983396,"score_spread":0.2672337276790158,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040894660","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923385,0.0031084907,0.0017835328,0.0011592743,0.0002490074,0.00020191973,0.0000010535974,0.000026057887,0.001132201],"genre_scores_gemma":[0.9978288,0.00034971273,0.00022987492,0.0008018102,0.0006589651,0.0000031779055,0.0000011400265,0.00003271952,0.00009382969],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984836,0.00015161959,0.00039649478,0.00019214892,0.0005113593,0.0002647997],"domain_scores_gemma":[0.99865484,0.00010851021,0.00036157566,0.00025289442,0.00018839394,0.00043376378],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005608188,0.00021481562,0.00063314993,0.00027095643,0.0000749532,0.000008298701,0.00008870503,0.00010876648,0.00012095449],"category_scores_gemma":[0.00045370922,0.00015427326,0.00017748305,0.00018411834,0.00017512188,0.0001033178,0.000037240934,0.0004927502,0.0000029747846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012405543,0.00014190986,0.003947921,0.00014976315,0.00046621694,0.0012737084,0.00046010732,0.000008031788,0.98326546,0.00018428871,0.0002717863,0.008590259],"study_design_scores_gemma":[0.009321982,0.002547302,0.34519947,0.0009715777,0.0008821142,0.0027875819,0.00015920778,0.0003912354,0.6357973,0.00094392936,0.0007592488,0.00023904402],"about_ca_topic_score_codex":0.00001333848,"about_ca_topic_score_gemma":6.305313e-7,"teacher_disagreement_score":0.34746814,"about_ca_system_score_codex":0.00010995728,"about_ca_system_score_gemma":0.00010056883,"threshold_uncertainty_score":0.62910813},"labels":[],"label_agreement":null},{"id":"W2040918084","doi":"10.4161/cc.28929","title":"Coffee induces autophagy in vivo","year":2014,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Cancer Research; Ligue Contre le Cancer; Institut National Du Cancer; Association pour la Recherche sur le Cancer","keywords":"Autophagy; Biology; Sequestosome 1; mTORC1; Cell biology; P70-S6 Kinase 1; Acetylation; Phosphorylation; In vivo; Biochemistry; Apoptosis; Gene; Biotechnology","score_opus":0.007799644522286903,"score_gpt":0.2482367208671164,"score_spread":0.2404370763448295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040918084","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9109259,0.00038008392,0.00003601363,0.0001637834,0.00013081134,0.00011597145,0.000001407958,0.0000603335,0.088185646],"genre_scores_gemma":[0.99559903,0.000032284643,0.000109447545,0.0012100898,0.00016624719,0.0000118534645,0.000003767481,0.000016957125,0.0028503442],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993675,0.00003074276,0.0001322362,0.00016429315,0.000118911135,0.0001863607],"domain_scores_gemma":[0.9995702,0.0000387456,0.000030936102,0.00023722231,0.000015031176,0.00010785737],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000106875974,0.000089495414,0.0001682434,0.00006648548,0.00002837242,0.000008339587,0.000072910545,0.00006847495,0.0012172427],"category_scores_gemma":[0.000018408906,0.00007846694,0.00005026112,0.00011014269,0.000034517554,0.000042556156,0.000017798975,0.00010922367,0.00026496546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045722828,0.0021477435,0.024615109,0.00034502996,0.0000825096,0.0003591185,0.0022463952,0.00010872702,0.9108499,0.004222653,0.014767305,0.03979824],"study_design_scores_gemma":[0.0033557492,0.00023860016,0.09591917,0.000058701808,0.00003288233,0.000009155938,0.000087194305,0.0012322282,0.85930413,0.0031840676,0.036379687,0.00019842116],"about_ca_topic_score_codex":0.00003501761,"about_ca_topic_score_gemma":0.0000040398736,"teacher_disagreement_score":0.0853353,"about_ca_system_score_codex":0.00002400939,"about_ca_system_score_gemma":0.000035596615,"threshold_uncertainty_score":0.9996958},"labels":[],"label_agreement":null},{"id":"W2041638315","doi":"10.1007/s00018-011-0660-3","title":"Alternative pathways for MHC class I presentation: a new function for autophagy","year":2011,"lang":"en","type":"review","venue":"Cellular and Molecular Life Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Antigen processing; MHC class I; Antigen presentation; Cross-presentation; Cell biology; Antigen; Biology; MHC restriction; Major histocompatibility complex; Autophagy; MHC class II; Transporter associated with antigen processing; Proteasome; Immune system; Immunology; T cell; Genetics; Apoptosis","score_opus":0.1012425796117993,"score_gpt":0.35442736402832115,"score_spread":0.2531847844165218,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041638315","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009364958,0.92351604,0.07249398,0.000042253476,0.0005536183,0.002299992,0.000046452653,0.000041435454,0.00091260567],"genre_scores_gemma":[0.00037089415,0.9948522,0.0016587195,0.0006034671,0.0006890199,0.00048306028,0.000235439,0.00004715579,0.0010600638],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99838597,0.00006116356,0.000369696,0.0006328993,0.0002384392,0.00031185156],"domain_scores_gemma":[0.99896425,0.00010579653,0.0002577452,0.00023995244,0.00009266013,0.0003396152],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030295993,0.00032026583,0.00081255025,0.00017928147,0.00021696281,0.000052432435,0.0002040112,0.00019291112,0.000053860673],"category_scores_gemma":[0.00011138631,0.0002383521,0.00054691173,0.00021668126,0.00021925445,0.00009630711,0.000039821913,0.00010824169,0.000009514747],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016385599,0.00015632791,0.0000016268352,0.008455135,0.0007724816,0.000035299978,0.00030092476,0.0000024326034,0.0004618963,0.04428236,0.003010863,0.9423568],"study_design_scores_gemma":[0.0010466995,0.00097205123,0.0000014862766,0.0012237433,0.0017157774,0.000015010189,0.0000487677,0.0002704807,0.001960038,0.010188583,0.98226887,0.00028850674],"about_ca_topic_score_codex":0.000016394097,"about_ca_topic_score_gemma":5.24217e-7,"teacher_disagreement_score":0.979258,"about_ca_system_score_codex":0.000024206292,"about_ca_system_score_gemma":0.0010271803,"threshold_uncertainty_score":0.97197163},"labels":[],"label_agreement":null},{"id":"W2042062304","doi":"10.1038/cdd.2008.185","title":"The role of Bcl-2 family member BNIP3 in cell death and disease: NIPping at the heels of cell death","year":2009,"lang":"en","type":"review","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":216,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Research Manitoba","funders":"Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"Programmed cell death; Cell biology; Autophagy; Apoptosis; Biology; Psychological repression; Cell; Hypoxia (environmental); Necrosis; Cell growth; Mitochondrion; Cancer research; Chemistry; Gene expression; Genetics; Gene; Oxygen","score_opus":0.024702773093576005,"score_gpt":0.28291853939197054,"score_spread":0.25821576629839454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042062304","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.16439357,0.8315273,0.000027426902,0.000015940046,0.00007268035,0.0009959806,0.000059520622,0.000014799199,0.0028928146],"genre_scores_gemma":[0.24293995,0.7553459,0.000015788504,0.00006450468,0.00007437591,0.000046092056,0.00023858645,0.00003393028,0.0012409101],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99791276,0.00022059254,0.0007397923,0.00043341058,0.00035944307,0.00033399518],"domain_scores_gemma":[0.99823916,0.0002972295,0.0005835941,0.0005518414,0.00007052661,0.0002576564],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022880295,0.00044608986,0.0010784154,0.00014083496,0.00017644982,0.00003865068,0.0001752638,0.00023065589,0.000044112985],"category_scores_gemma":[0.000021976637,0.00025191985,0.00034013792,0.00015667168,0.00007232913,0.00006198392,0.000090921945,0.00026901675,0.0000059796857],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008763,0.002122356,0.037243664,0.038219728,0.0005285211,0.000060772334,0.0010852511,0.000007865422,0.0041107675,0.0013608099,0.0005702816,0.9138137],"study_design_scores_gemma":[0.012207268,0.0011005515,0.36812016,0.021306736,0.01666833,0.000035555513,0.00063455047,0.0018664158,0.011084313,0.009549838,0.5549861,0.0024401508],"about_ca_topic_score_codex":0.000035082674,"about_ca_topic_score_gemma":0.000006479781,"teacher_disagreement_score":0.91137356,"about_ca_system_score_codex":0.000076215976,"about_ca_system_score_gemma":0.00020667643,"threshold_uncertainty_score":0.9999933},"labels":[],"label_agreement":null},{"id":"W2042349286","doi":"10.1016/j.cmet.2013.08.012","title":"The REGγ Proteasome Regulates Hepatic Lipid Metabolism through Inhibition of Autophagy","year":2013,"lang":"en","type":"article","venue":"Cell Metabolism","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Autophagy; Proteasome; Lipid metabolism; Metabolism; Cell biology; Chemistry; Biology; Biochemistry","score_opus":0.009129381016354148,"score_gpt":0.23692083380356213,"score_spread":0.22779145278720797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042349286","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96319747,0.028462555,0.00008955265,0.0010723049,0.0006490886,0.0016586974,0.000009772008,0.00012954255,0.0047310116],"genre_scores_gemma":[0.9895785,0.00237316,0.001128505,0.0007485243,0.000785686,0.00038601452,0.000026811222,0.000062951665,0.0049098693],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99790245,0.0001713813,0.0006139141,0.00035768014,0.0004938053,0.00046075656],"domain_scores_gemma":[0.99817914,0.00012685105,0.00033621752,0.0008840495,0.0002928957,0.00018086853],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027996735,0.00030512977,0.00063832226,0.00008506885,0.00021924442,0.00005205072,0.00020491892,0.00016407251,0.0006763184],"category_scores_gemma":[0.00011265856,0.0001936589,0.00031230232,0.00035756806,0.0002521692,0.0003440271,0.00007074066,0.00026551416,0.00033492816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031421418,0.0009018023,0.00018015542,0.00044661228,0.0004829922,0.00002699422,0.0023055978,0.000013028966,0.9358057,0.029483726,0.008576871,0.021462345],"study_design_scores_gemma":[0.0022328764,0.000072739975,0.038098436,0.00008389493,0.00039469707,0.000012200581,0.00016834043,0.00023872967,0.87691766,0.023610676,0.05793738,0.00023237207],"about_ca_topic_score_codex":0.00016658752,"about_ca_topic_score_gemma":0.0000014630025,"teacher_disagreement_score":0.058888007,"about_ca_system_score_codex":0.000022163747,"about_ca_system_score_gemma":0.00012694029,"threshold_uncertainty_score":0.78971803},"labels":[],"label_agreement":null},{"id":"W204282937","doi":"10.1096/fasebj.27.1_supplement.994.8","title":"Effect of a six week exercise training program on proteolytic enzyme activity, ROS generation and autophagy in the white gastrocnemius and left ventricle of normotensive and hypertensive rats","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Internal medicine; Autophagy; Endocrinology; Ventricle; Medicine; Gastrocnemius muscle; Downregulation and upregulation; Skeletal muscle; Chemistry; Apoptosis; Biochemistry; Gene","score_opus":0.019197859993419313,"score_gpt":0.2668526039152247,"score_spread":0.2476547439218054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W204282937","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968763,0.0010388764,0.000021373811,0.0005662387,0.00002842954,0.0014374966,0.0000028412533,0.0000068179297,0.000021650521],"genre_scores_gemma":[0.99940634,0.00018774689,0.000091286965,0.00016295475,0.00008673498,0.000033016495,0.000001551958,0.0000115897055,0.000018755802],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990532,0.00022012726,0.0001997117,0.00012561143,0.00022048841,0.000180859],"domain_scores_gemma":[0.9993409,0.00015696607,0.00017721347,0.00013316727,0.000100606034,0.00009112918],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004606689,0.00013735799,0.00033657474,0.00008678916,0.00010596041,0.000039817696,0.00005786635,0.000047655583,0.000014527221],"category_scores_gemma":[0.00008815685,0.00007125433,0.00004918245,0.00008664318,0.00015906562,0.00011055274,0.000020944126,0.00026845935,7.250365e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011273355,0.00030700388,0.0033706604,0.000121229474,0.00010169836,0.00012957396,0.0077663325,0.000036299945,0.80231845,0.000007392766,0.000074220254,0.18463981],"study_design_scores_gemma":[0.005690265,0.007934184,0.2017003,0.00056674954,0.00036288323,0.0022099374,0.0014137002,0.011707468,0.7681549,0.000120867386,0.000004420119,0.00013427342],"about_ca_topic_score_codex":0.000017935563,"about_ca_topic_score_gemma":0.0000021468572,"teacher_disagreement_score":0.19832964,"about_ca_system_score_codex":0.0000144700825,"about_ca_system_score_gemma":0.000057007775,"threshold_uncertainty_score":0.29056674},"labels":[],"label_agreement":null},{"id":"W2042840607","doi":"10.1371/journal.pone.0036916","title":"Extracellular Nucleotides Inhibit Insulin Receptor Signaling, Stimulate Autophagy and Control Lipoprotein Secretion","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Government of Ontario; Heart and Stroke Foundation of Canada","keywords":"Secretion; Biology; Phosphorylation; Autophagy; Cell biology; Protein kinase B; Signal transduction; Kinase; Endocrinology; Internal medicine; Biochemistry; Apoptosis","score_opus":0.028025756648759583,"score_gpt":0.2342219394553334,"score_spread":0.2061961828065738,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042840607","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9789181,0.019070353,0.00035676174,0.0003698576,0.00005056534,0.00083539967,0.000020029149,0.00017689467,0.00020206586],"genre_scores_gemma":[0.995352,0.0003063408,0.0019210629,0.00041776846,0.000662404,0.000057315545,0.000046093024,0.000050245497,0.0011867512],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986521,0.000081823084,0.0002986107,0.00023846091,0.0003605716,0.00036841191],"domain_scores_gemma":[0.9991106,0.00006518503,0.00011399377,0.00025543675,0.0000902886,0.00036450956],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00031640384,0.00020054822,0.0003965143,0.000089271896,0.00009705919,0.000023366285,0.000053441243,0.00014711493,0.0016619817],"category_scores_gemma":[0.000119423625,0.00018345925,0.000071565424,0.000108461056,0.00008559762,0.00019710003,0.000022286165,0.00022754548,0.00028423173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006028375,0.0021984254,0.0056730392,0.00022903584,0.00048733532,0.000019366313,0.00049606967,0.0000039241836,0.98630595,0.00035900882,0.00004643472,0.0035785942],"study_design_scores_gemma":[0.0062608486,0.0006397617,0.018405283,0.0006614086,0.0007467871,0.000009554972,0.000058545473,0.0024425609,0.9689608,0.00041697331,0.0010448024,0.00035264637],"about_ca_topic_score_codex":0.000023271123,"about_ca_topic_score_gemma":4.084093e-7,"teacher_disagreement_score":0.018764012,"about_ca_system_score_codex":0.000044320812,"about_ca_system_score_gemma":0.00003654329,"threshold_uncertainty_score":0.99925065},"labels":[],"label_agreement":null},{"id":"W2042910045","doi":"10.1007/s00401-015-1396-1","title":"Autophagy in neuropathology","year":2015,"lang":"en","type":"editorial","venue":"Acta Neuropathologica","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Neuropathology; Autophagy; Neuroscience; Medicine; Biology; Pathology; Biochemistry; Disease; Apoptosis","score_opus":0.019996955341418005,"score_gpt":0.3141932082115657,"score_spread":0.2941962528701477,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042910045","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10902091,0.002401438,0.000003364952,0.0005016238,0.8662208,0.00086249015,0.000167985,0.00052775367,0.020293647],"genre_scores_gemma":[0.16866253,0.0023460544,0.00019412226,0.002730303,0.8158213,0.00017669595,0.00068960246,0.00036579664,0.009013618],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9957653,0.00065389293,0.0007124961,0.0012451365,0.0008786376,0.00074451836],"domain_scores_gemma":[0.9973688,0.00038094245,0.00032735238,0.0012570977,0.0002963209,0.00036946035],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0007166976,0.00065668696,0.0013250064,0.0004184965,0.000045367426,0.000037348324,0.0005290708,0.0013839881,0.0002522359],"category_scores_gemma":[0.004052982,0.00054620695,0.00027327248,0.00041106864,0.00025106085,0.00008849352,0.00027627268,0.002437283,0.0007303647],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005928952,0.00048808285,0.00013997566,0.00009074957,0.000015576954,0.04515409,0.00009812551,8.4150605e-7,0.003148389,0.000013953185,0.9493884,0.00086891546],"study_design_scores_gemma":[0.0025026242,0.0017291005,0.0068691955,0.000106808366,0.00014963732,0.0005383115,0.000012757047,0.000010678401,0.00020902522,0.00055099116,0.98685867,0.00046217706],"about_ca_topic_score_codex":0.000008656069,"about_ca_topic_score_gemma":0.0000018904607,"teacher_disagreement_score":0.059641626,"about_ca_system_score_codex":0.00013564502,"about_ca_system_score_gemma":0.0006319656,"threshold_uncertainty_score":0.99991244},"labels":[],"label_agreement":null},{"id":"W2043260789","doi":"10.4161/15548627.2014.981915","title":"Mitochondrial damage contributes to<i>Pseudomonas aeruginosa</i>activation of the inflammasome and is downregulated by autophagy","year":2015,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":155,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Biotechnology and Biological Sciences Research Council; Wellcome Trust","keywords":"NLRC4; Inflammasome; Autophagy; Biology; Cell biology; AIM2; Mitochondrion; Reactive oxygen species; Mitochondrial DNA; Caspase 1; Biochemistry; Apoptosis; Receptor","score_opus":0.011234435719034892,"score_gpt":0.2522010504238168,"score_spread":0.2409666147047819,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043260789","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927838,0.0010990914,0.00022673793,0.0034411957,0.00046754765,0.00093703106,0.0000646135,0.00010291853,0.0008770545],"genre_scores_gemma":[0.99338007,0.000027438598,0.00024099875,0.003431584,0.00018774263,0.000045032164,0.00004619919,0.000035393263,0.0026055432],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99828124,0.000098133554,0.00045176045,0.00037694525,0.00045573167,0.00033617005],"domain_scores_gemma":[0.9985122,0.000107369066,0.00018879204,0.000614024,0.0002646106,0.00031300206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017967967,0.00026334688,0.00047887088,0.00012366462,0.00009906682,0.000034280565,0.00021701053,0.00019989665,0.000120810946],"category_scores_gemma":[0.00024894578,0.00019161939,0.00013045491,0.00048192256,0.00020430278,0.00016578485,0.0001240058,0.00019895504,0.00003377781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011468943,0.00036106206,0.003642474,0.00007106311,0.00041304552,0.000025453746,0.0015926871,0.00002746088,0.9234843,0.002826731,0.062380135,0.004028659],"study_design_scores_gemma":[0.0058668093,0.00029792212,0.079480305,0.00011477259,0.00014641702,0.000016595772,0.00008165354,0.00035284777,0.8853271,0.0018793842,0.026235482,0.00020073616],"about_ca_topic_score_codex":0.000129594,"about_ca_topic_score_gemma":0.0000025127563,"teacher_disagreement_score":0.07583783,"about_ca_system_score_codex":0.00009423379,"about_ca_system_score_gemma":0.0002569659,"threshold_uncertainty_score":0.78140116},"labels":[],"label_agreement":null},{"id":"W2043262554","doi":"10.1161/jaha.113.000191","title":"Cathepsin‐L Ameliorates Cardiac Hypertrophy Through Activation of the Autophagy–Lysosomal Dependent Protein Processing Pathways","year":2013,"lang":"en","type":"article","venue":"Journal of the American Heart Association","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; University Health Network; Toronto General Hospital; University of Toronto; McMaster University; Heart and Stroke Foundation","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Cathepsin L; Cell biology; Ubiquitin; Proteasome; Protein turnover; Protein degradation; Endoplasmic reticulum; Unfolded protein response; Medicine; Muscle hypertrophy; Endocrinology; Internal medicine; Cathepsin; Biology; Apoptosis; Protein biosynthesis; Molecular biology; Biochemistry; Enzyme","score_opus":0.012834983659037937,"score_gpt":0.2571112803390364,"score_spread":0.24427629667999848,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043262554","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99510187,0.00025875136,0.000051638912,0.0037527515,0.00019543484,0.0005200294,0.0000045098545,0.000012984129,0.00010203928],"genre_scores_gemma":[0.9978855,0.00002891431,0.00054932607,0.0009145368,0.00036107298,0.000017734026,7.35083e-7,0.000020249518,0.00022189396],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99815553,0.00031486596,0.00045807753,0.00010408099,0.0007765119,0.00019092957],"domain_scores_gemma":[0.9975632,0.000091215436,0.0014858688,0.00023473424,0.00057002984,0.000054987642],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037624317,0.00012751165,0.0004997826,0.000048335456,0.00016430151,0.000036384467,0.00016948268,0.00005620108,0.000020085783],"category_scores_gemma":[0.00038114653,0.000069474074,0.00042177664,0.00043729827,0.00008851729,0.0003130331,0.000036970272,0.0003088623,0.0000070543115],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001360271,0.0002706861,0.1686904,0.00003630743,0.00029472765,0.0000010472587,0.0011626857,0.00006507283,0.8226942,0.000027673137,0.0011107689,0.0055104466],"study_design_scores_gemma":[0.00046803732,0.0002636354,0.6620479,0.00019473059,0.00014995581,0.000010757507,0.00047008973,0.00010870494,0.3350692,0.0008323891,0.00030875963,0.00007583185],"about_ca_topic_score_codex":0.00021281456,"about_ca_topic_score_gemma":7.7303935e-7,"teacher_disagreement_score":0.4933575,"about_ca_system_score_codex":0.00042122515,"about_ca_system_score_gemma":0.00037497596,"threshold_uncertainty_score":0.28330705},"labels":[],"label_agreement":null},{"id":"W2043610862","doi":"10.4161/auto.8.2.18981","title":"Oxidative stress and autophagy","year":2012,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Alzheimer Society","keywords":"Autophagy; Oxidative stress; Biology; Cell biology; Reactive oxygen species; Synapse; Oxidative phosphorylation; Neuroscience; Biochemistry; Apoptosis","score_opus":0.01601137834943013,"score_gpt":0.2927109839730603,"score_spread":0.27669960562363016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043610862","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98051447,0.008329512,0.00016908991,0.00023216642,0.00031598622,0.0002834449,0.000021160073,0.00018998673,0.009944182],"genre_scores_gemma":[0.9942668,0.00021711938,0.00060555164,0.0013945388,0.00047461106,0.000032411783,0.00003253268,0.000034725246,0.0029416922],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99882793,0.00004697788,0.00020416595,0.00023700298,0.00022306584,0.00046084434],"domain_scores_gemma":[0.99907124,0.00007048804,0.00006722494,0.00032757962,0.00004779824,0.00041564388],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00013516784,0.00020289914,0.00030069414,0.00009230446,0.00009916824,0.000018643095,0.00007419281,0.00011542614,0.0010252671],"category_scores_gemma":[0.000046059882,0.00017058944,0.00008424964,0.00014521813,0.00012958613,0.00024969113,0.000057593952,0.00016954984,0.00024323515],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001654102,0.0072696432,0.2809486,0.001262873,0.003041121,0.0011419753,0.017242309,0.0000072745756,0.25880283,0.13257274,0.014099626,0.2819569],"study_design_scores_gemma":[0.0021793419,0.00026012835,0.60312057,0.0000829281,0.00017939182,0.00013955087,0.00023972831,0.00011232867,0.37726226,0.00073991047,0.015388874,0.00029497594],"about_ca_topic_score_codex":0.000022494207,"about_ca_topic_score_gemma":8.2899925e-7,"teacher_disagreement_score":0.32217196,"about_ca_system_score_codex":0.000040092087,"about_ca_system_score_gemma":0.000058624402,"threshold_uncertainty_score":0.99988794},"labels":[],"label_agreement":null},{"id":"W2043914352","doi":"10.1016/j.cardfail.2009.06.306","title":"The Role of Autophagy in Iron-Overload Cardiomyopathy: A Model of Diastolic Heart Failure Due to Oxidative Stress","year":2009,"lang":"en","type":"article","venue":"Journal of Cardiac Failure","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto; Lakehead University; University Health Network","funders":"","keywords":"Medicine; Heart failure; Oxidative stress; Autophagy; Internal medicine; Cardiology; Cardiomyopathy; Diastole; Diastolic heart failure; Biochemistry; Ejection fraction","score_opus":0.005623202626947004,"score_gpt":0.24896523403569068,"score_spread":0.24334203140874366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043914352","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99002504,0.006627355,0.00010316905,0.0022967653,0.00010929692,0.00036937345,0.000082454,0.000008483984,0.0003780546],"genre_scores_gemma":[0.9979689,0.00019541394,0.0012787669,0.00022718325,0.000265124,0.0000067734395,0.0000032174844,0.000018045188,0.00003654644],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979167,0.00015724765,0.0007474673,0.00016790211,0.0007057681,0.00030492625],"domain_scores_gemma":[0.99836665,0.00012475719,0.00042717243,0.0004233974,0.00041279,0.00024524654],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005057674,0.00021955663,0.0010675396,0.00025670303,0.000048218524,0.000015921149,0.00023562733,0.00013884566,0.000011187342],"category_scores_gemma":[0.0001285505,0.00015225107,0.0006760404,0.0003656284,0.000079041216,0.00017130053,0.00003438717,0.0004074521,0.0000032200237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0052212486,0.0015140028,0.0462736,0.00027307766,0.0019736518,0.00031924763,0.013548657,0.0347225,0.79878825,0.0041552675,0.014138919,0.079071596],"study_design_scores_gemma":[0.005433056,0.0032153947,0.29650354,0.0014551466,0.0009252469,0.0002833141,0.008327981,0.0015753135,0.6512873,0.0051123933,0.025266778,0.00061449496],"about_ca_topic_score_codex":0.000024605835,"about_ca_topic_score_gemma":0.000010216996,"teacher_disagreement_score":0.25022995,"about_ca_system_score_codex":0.000092812865,"about_ca_system_score_gemma":0.00040612495,"threshold_uncertainty_score":0.6208618},"labels":[],"label_agreement":null},{"id":"W2044515182","doi":"10.1083/jcb.200712091","title":"Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during <i>Drosophila melanogaster</i> oogenesis","year":2008,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":183,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Genome British Columbia","funders":"Division of Graduate Education; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; National Science Foundation","keywords":"Autophagy; Biology; Cell biology; Programmed cell death; Drosophila melanogaster; Effector; BAG3; Apoptosis; Oogenesis; Genetics; Gene; Oocyte","score_opus":0.014845018618713643,"score_gpt":0.2413613284629353,"score_spread":0.22651630984422164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044515182","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99662834,0.0021816005,0.000023321267,0.0005257847,0.00014318834,0.00033168873,0.0000061541487,0.000017903832,0.00014200239],"genre_scores_gemma":[0.99805826,0.00060314045,0.00016378322,0.00034136506,0.00036963943,0.00000501408,0.0000036217464,0.000022252942,0.0004329477],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988101,0.00026179492,0.0004084756,0.00013043736,0.000150464,0.00023869144],"domain_scores_gemma":[0.99896944,0.0001236023,0.00036580025,0.0002450511,0.00013320261,0.00016291418],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035333115,0.00017384077,0.00039771688,0.00010779817,0.0001763654,0.0000053887366,0.00013908822,0.00011932136,0.00008288648],"category_scores_gemma":[0.00004706414,0.000105891384,0.00011012324,0.00011433556,0.00015008527,0.00006873619,0.00003898054,0.0002390067,0.000017089222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011993238,0.00010361438,0.00062077737,0.000055356286,0.00012132581,0.00027759094,0.00036703478,0.00000566966,0.9967861,0.000015905609,0.000028289869,0.0004189788],"study_design_scores_gemma":[0.0025208695,0.0010116834,0.043519404,0.000060018534,0.00014206888,0.0016553943,0.00002891939,0.000028180304,0.950473,0.00023630235,0.00022074052,0.00010338723],"about_ca_topic_score_codex":0.000021075395,"about_ca_topic_score_gemma":0.0000013950447,"teacher_disagreement_score":0.0463131,"about_ca_system_score_codex":0.000043235086,"about_ca_system_score_gemma":0.00012834516,"threshold_uncertainty_score":0.43181252},"labels":[],"label_agreement":null},{"id":"W2045122835","doi":"10.15252/embj.201490784","title":"Autophagy in malignant transformation and cancer progression","year":2015,"lang":"en","type":"review","venue":"The EMBO Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1161,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Cancer Research; National Cancer Institute; Labex Immuno-Oncology; Institut National Du Cancer; National Institute of General Medical Sciences; Fondation de France; Ministero della Salute; Fondation pour la Recherche Médicale; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Wellcome Trust; European Regional Development Fund; European Commission; Fundación Mutua Madrileña; Fundació la Marató de TV3; Association pour la Recherche sur le Cancer; Cancer Research UK; American Cancer Society","keywords":"Cancer; Humanities; Library science; Art; Medicine; Art history; Internal medicine","score_opus":0.07227273717708904,"score_gpt":0.42934645902053675,"score_spread":0.3570737218434477,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2045122835","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014617584,0.99680257,0.000010274189,0.0002734898,0.00024811822,0.0006128294,0.0000065985437,0.000013592075,0.0005707873],"genre_scores_gemma":[0.0002639377,0.99883574,0.000021997172,0.000103416176,0.00046623673,0.000054755008,0.000011383318,0.000026052452,0.00021650258],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987631,0.00017691372,0.00045739036,0.000108202934,0.00029612507,0.00019826482],"domain_scores_gemma":[0.9993686,0.00002608275,0.00024546366,0.00014394043,0.00005193804,0.00016398611],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00073340087,0.00020072071,0.0007686763,0.00013643838,0.00008381422,0.000037819802,0.00011443953,0.000119899814,0.00014996967],"category_scores_gemma":[0.000010314737,0.00009343701,0.0001661657,0.00014811358,0.00004962826,0.000089528905,0.000014659468,0.00062458083,0.000014301032],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040492803,0.000039768187,0.000004536385,0.0015296885,0.000089321446,0.00012694296,0.0005113391,3.7205228e-7,8.455998e-7,0.000052478208,0.00037404776,0.9972302],"study_design_scores_gemma":[0.0009167691,0.00010786543,0.00006375347,0.02077862,0.0007028855,0.0025788895,0.000048315345,0.000030191335,0.000007909175,0.00048330554,0.9741596,0.00012189253],"about_ca_topic_score_codex":0.000005715912,"about_ca_topic_score_gemma":0.0000017564287,"teacher_disagreement_score":0.9971083,"about_ca_system_score_codex":0.00015141815,"about_ca_system_score_gemma":0.00066992,"threshold_uncertainty_score":0.38102508},"labels":[],"label_agreement":null},{"id":"W2045332860","doi":"10.1016/j.fob.2014.08.005","title":"ROS‐dependent prostate apoptosis response‐4 (Par‐4) up‐regulation and ceramide generation are the prime signaling events associated with curcumin‐induced autophagic cell death in human malignant glioma","year":2014,"lang":"en","type":"article","venue":"FEBS Open Bio","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"United Arab Emirates University; Terry Fox Foundation; Sheikh Hamdan Bin Rashid Al Maktoum Award for Medical Sciences; Al Jalila Foundation","keywords":"Curcumin; Autophagy; Ceramide; Programmed cell death; Glioma; Cancer research; Apoptosis; Cell biology; Cell growth; Biology; Chemistry; Pharmacology; Biochemistry","score_opus":0.03296608191962801,"score_gpt":0.28868925160094133,"score_spread":0.2557231696813133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2045332860","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972646,0.0001052292,0.00011756722,0.00046999508,0.00008620589,0.0017464998,0.000018885914,0.000047173067,0.00014384501],"genre_scores_gemma":[0.99795604,0.00000656587,0.00007799715,0.0002902772,0.00008580024,0.00013903504,0.00017999281,0.000045630128,0.0012186684],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979395,0.00052288343,0.0003923933,0.00046919807,0.00035152142,0.00032450323],"domain_scores_gemma":[0.9989207,0.00008711754,0.00034477585,0.0004041363,0.0001155695,0.00012774109],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011868217,0.0002559866,0.00035806742,0.00014387308,0.00034222798,0.0001616091,0.00021583882,0.00013216834,0.00005441429],"category_scores_gemma":[0.00007456891,0.00017406126,0.000048644495,0.00027292676,0.000041239044,0.00023222803,0.00009648719,0.00017549143,0.000010765797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015248624,0.00031361397,0.058913127,0.00002239496,0.000102971346,0.000018161702,0.00093527173,0.00009575427,0.93742144,0.0000694216,0.000049424976,0.0005335459],"study_design_scores_gemma":[0.0035319244,0.0004506525,0.43387413,0.00021598818,0.00009006748,0.0000061866954,0.000097834825,0.0017463476,0.559591,0.00019052622,0.000026461297,0.00017887789],"about_ca_topic_score_codex":0.00022037298,"about_ca_topic_score_gemma":0.00005632571,"teacher_disagreement_score":0.37783045,"about_ca_system_score_codex":0.00017610693,"about_ca_system_score_gemma":0.00012059278,"threshold_uncertainty_score":0.7098012},"labels":[],"label_agreement":null},{"id":"W2045433709","doi":"10.2174/2212697x01666131218235200","title":"Impaired Autophagy Mediates Resistance to Low-Dose Metronomic Cyclophosphamide Chemotherapy","year":2014,"lang":"en","type":"article","venue":"Clinical Cancer Drugs","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; Health Sciences Centre","funders":"","keywords":"Autophagy; Chemotherapy; Cyclophosphamide; Cancer research; Context (archaeology); Medicine; Cancer; Pharmacology; Biology; Internal medicine; Apoptosis","score_opus":0.0181575095889613,"score_gpt":0.35312924604020474,"score_spread":0.33497173645124345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2045433709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98498774,0.0038633836,0.00014049726,0.006898774,0.0011986045,0.00060943956,0.000025796755,0.0002443203,0.0020314676],"genre_scores_gemma":[0.96455896,0.0019105235,0.00097338815,0.025388628,0.0019385626,0.00018272657,0.00001999007,0.000085339845,0.0049418574],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99734956,0.00014377302,0.00088238023,0.0007245219,0.00035510023,0.0005446586],"domain_scores_gemma":[0.9974333,0.0005742772,0.00021583485,0.0008481713,0.00012518011,0.00080321287],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008790925,0.000320006,0.0008653754,0.00007309946,0.00009563666,0.000027615364,0.00032489147,0.00021296997,0.001252148],"category_scores_gemma":[0.0003685424,0.0002745226,0.000430983,0.0003153087,0.00020762395,0.000082581675,0.000057322068,0.00034305465,0.0004489194],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.017795041,0.0029689819,0.1019752,0.0005862922,0.0018426896,0.00010356038,0.00233179,0.00013046816,0.0045104283,0.0017685165,0.16449077,0.70149624],"study_design_scores_gemma":[0.013772026,0.00083761907,0.6795901,0.00045953627,0.00028507964,0.0000022454758,0.00009955501,0.00075234973,0.028017037,0.0025273878,0.2728592,0.0007978512],"about_ca_topic_score_codex":0.00007579925,"about_ca_topic_score_gemma":0.000028376582,"teacher_disagreement_score":0.7006984,"about_ca_system_score_codex":0.00021896728,"about_ca_system_score_gemma":0.00039054596,"threshold_uncertainty_score":0.9999707},"labels":[],"label_agreement":null},{"id":"W2047219888","doi":"10.1038/nrd3373","title":"Cell death assays for drug discovery","year":2011,"lang":"en","type":"review","venue":"Nature Reviews Drug Discovery","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":554,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer","keywords":"Programmed cell death; Drug discovery; Computational biology; Cause of death; Medicine; Bioinformatics; Biology; Apoptosis; Disease; Pathology","score_opus":0.043820399536659005,"score_gpt":0.3593117519142114,"score_spread":0.3154913523775524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047219888","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000012472688,0.9785859,0.00023607441,0.0000645824,0.001924843,0.008700972,0.00095810456,0.0001380384,0.009379017],"genre_scores_gemma":[0.000019395844,0.9388628,0.00066163286,0.0014383119,0.0023224326,0.001749812,0.0024126216,0.00036897935,0.052164026],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9942153,0.00053574925,0.0020089531,0.0016426302,0.0005837732,0.0010135678],"domain_scores_gemma":[0.9949873,0.00055768515,0.0015531671,0.002308674,0.00013830765,0.00045485958],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.0013129752,0.0017533097,0.007019784,0.00040162378,0.00020673205,0.00023568467,0.0009928347,0.0014071956,0.00020180212],"category_scores_gemma":[0.00030390345,0.0011265465,0.006026934,0.0005935895,0.00012255668,0.0009378053,0.0002237881,0.002815571,0.00048989675],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001425884,0.0008969205,0.000013673648,0.1531426,0.00085170334,0.00010938947,0.00010055032,5.6989066e-8,0.000001553204,0.0045732204,0.20375222,0.63641554],"study_design_scores_gemma":[0.0009335997,0.000080322716,0.000006263907,0.04496729,0.007828969,0.00007184048,0.000012960853,7.4767087e-7,0.000029653444,0.0005527943,0.9444502,0.0010653546],"about_ca_topic_score_codex":0.000015714955,"about_ca_topic_score_gemma":0.000005396174,"teacher_disagreement_score":0.740698,"about_ca_system_score_codex":0.0004087254,"about_ca_system_score_gemma":0.0013541923,"threshold_uncertainty_score":0.9998892},"labels":[],"label_agreement":null},{"id":"W2047326920","doi":"10.1074/jbc.m114.607150","title":"Short Mitochondrial ARF Triggers Parkin/PINK1-dependent Mitophagy","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"Parkin; Mitophagy; PINK1; Mitochondrion; Cell biology; Biology; Autophagy; Substantia nigra; Parkinson's disease; Neuroscience; Dopaminergic; Biochemistry; Dopamine; Medicine; Apoptosis; Disease","score_opus":0.022153468556785027,"score_gpt":0.28095649336029327,"score_spread":0.25880302480350825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047326920","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929123,0.0012517768,0.00030631034,0.00038243196,0.00040475,0.000081210965,0.000004606529,0.000027731063,0.0046289116],"genre_scores_gemma":[0.99526954,0.00030678717,0.0004348285,0.0005106314,0.0029953546,0.000003483446,0.0000101136775,0.00001204836,0.00045724172],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986004,0.00005098943,0.0005516524,0.00019949621,0.00034103153,0.00025642742],"domain_scores_gemma":[0.9989311,0.00012198573,0.00021984437,0.00022326114,0.00013328357,0.00037052],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025887002,0.0001850912,0.00051812344,0.000028820867,0.000046712583,0.000017230532,0.00021473329,0.00029732112,0.0007823422],"category_scores_gemma":[0.0003250095,0.00011550099,0.0004107869,0.00007678101,0.00012236717,0.00003855555,0.00003127163,0.00047724796,0.000019001494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019247467,0.0005363328,0.007349957,0.00005504814,0.00030686718,0.00042055117,0.000020623842,0.0000051879438,0.9712476,0.000018025767,0.002918134,0.015196893],"study_design_scores_gemma":[0.0035240967,0.00082863966,0.023595601,0.000112234375,0.0001623726,0.0010708119,0.000055438457,0.000025797739,0.9420853,0.0008087802,0.027490566,0.00024033048],"about_ca_topic_score_codex":6.0237807e-7,"about_ca_topic_score_gemma":4.059809e-8,"teacher_disagreement_score":0.0291623,"about_ca_system_score_codex":0.00006414319,"about_ca_system_score_gemma":0.00006561754,"threshold_uncertainty_score":0.8566098},"labels":[],"label_agreement":null},{"id":"W2048198700","doi":"10.1007/s13311-014-0320-z","title":"Promoting Autophagic Clearance: Viable Therapeutic Targets in Alzheimer's Disease","year":2014,"lang":"en","type":"review","venue":"Neurotherapeutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Weston Brain Institute; BrightFocus Foundation; National Institutes of Health; Alzheimer's Association","keywords":"Autophagy; PI3K/AKT/mTOR pathway; Cell biology; Autophagosome; Lysosome; Intracellular; Biology; Protein degradation; Neuroscience; Chemistry; Signal transduction; Biochemistry; Enzyme; Apoptosis","score_opus":0.05998631047213323,"score_gpt":0.36327875780372554,"score_spread":0.30329244733159233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048198700","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00004404822,0.9950089,0.00005176487,0.000158554,0.00050085713,0.0031338322,0.000031563824,0.00029656023,0.0007739457],"genre_scores_gemma":[0.0014777984,0.9922573,0.00007210741,0.0042943284,0.00058587175,0.00039629414,0.00011077045,0.00042338372,0.0003821319],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9957675,0.00051644264,0.0011516818,0.0010395977,0.0006074413,0.0009173825],"domain_scores_gemma":[0.9974267,0.00022085475,0.0004826439,0.0012858959,0.00007662473,0.000507271],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003761862,0.0009914844,0.002786151,0.00043333945,0.00012989911,0.00007816869,0.00049194164,0.0004869453,0.000427066],"category_scores_gemma":[0.000034194578,0.0008198544,0.0009438976,0.0007184883,0.00016337559,0.000101063706,0.000053297663,0.0012329711,0.00041256566],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013901808,0.00057001156,0.000057294314,0.008066045,0.000627255,0.00040122773,0.0001591392,0.0000026930616,0.0000042430283,0.0002543597,0.000056023997,0.9896627],"study_design_scores_gemma":[0.0012526946,0.0002785663,0.0002406235,0.007190019,0.003351206,0.00007192401,0.000003976373,0.0007854794,0.00001617557,0.00045475582,0.9856859,0.00066869176],"about_ca_topic_score_codex":0.0000044776834,"about_ca_topic_score_gemma":0.0000010467887,"teacher_disagreement_score":0.988994,"about_ca_system_score_codex":0.00013329746,"about_ca_system_score_gemma":0.0007920666,"threshold_uncertainty_score":0.99942523},"labels":[],"label_agreement":null},{"id":"W2048582093","doi":"10.1038/sj.cdd.4401738","title":"Mechanisms of cell death: molecular insights and therapeutic perspectives","year":2005,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias; Comisión Nacional de Investigación Científica y Tecnológica; International Union of Biochemistry and Molecular Biology","keywords":"Salient; Environmental ethics; Political science; Law; Philosophy","score_opus":0.010284819775973899,"score_gpt":0.23738784523042716,"score_spread":0.22710302545445327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048582093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9788069,0.010067471,0.008952178,0.000056680543,0.000024336208,0.00019081513,0.0000024702629,0.000022986218,0.0018761788],"genre_scores_gemma":[0.9979893,0.00093722227,0.00056523166,0.00017984949,0.000030742794,0.0000069748553,0.000017797756,0.000012943225,0.00025994368],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994412,0.000025798954,0.00012471699,0.00018177046,0.000121000405,0.00010550729],"domain_scores_gemma":[0.9996571,0.00001789349,0.00006157054,0.0001226812,0.00004450902,0.000096278614],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000025069485,0.000115426665,0.00016525807,0.00007433542,0.000047640493,0.0000124731005,0.000025512829,0.000067567315,0.000070040674],"category_scores_gemma":[0.0000028941045,0.00009205949,0.000047671554,0.00003999321,0.000021867978,0.000044252574,0.000013267302,0.000057247715,0.000003633057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014004338,0.00047836875,0.0025838309,0.00012619927,0.00006561754,0.000006733501,0.0023035393,0.0000026187495,0.9684484,0.022298846,0.000004260117,0.0035415527],"study_design_scores_gemma":[0.002247415,0.0002897768,0.16225651,0.000026768974,0.0002590061,0.000004475814,0.00042844066,0.0022424923,0.8174899,0.01455766,0.00006350318,0.00013405582],"about_ca_topic_score_codex":0.00000509844,"about_ca_topic_score_gemma":6.496787e-7,"teacher_disagreement_score":0.15967268,"about_ca_system_score_codex":0.000015493497,"about_ca_system_score_gemma":0.000018824,"threshold_uncertainty_score":0.3754077},"labels":[],"label_agreement":null},{"id":"W2048705639","doi":"10.1074/jbc.m509157200","title":"Autophagy Controls Salmonella Infection in Response to Damage to the Salmonella-containing Vacuole","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":648,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Natural Sciences and Engineering Research Council of Canada; Directorate for Biological Sciences; Ministero dello Sviluppo Economico; Burroughs Wellcome Fund; University of Toronto; Hospital for Sick Children; Ontario Innovation Trust","keywords":"Salmonella enterica; Intracellular parasite; Biology; Vacuole; Autophagy; Microbiology; Salmonella; Type three secretion system; Intracellular; ATG5; Bacteria; Cell biology; Virulence; Cytoplasm; Biochemistry; Gene; Genetics","score_opus":0.016603752306916818,"score_gpt":0.2871616320399662,"score_spread":0.2705578797330494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048705639","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956194,0.00047880123,0.00019975203,0.0023290676,0.000081131744,0.00019447849,0.000004896,0.000021450092,0.0010710331],"genre_scores_gemma":[0.997202,0.00003696623,0.00015629157,0.0015429672,0.0006357196,0.000010579888,0.0000038004737,0.000010548517,0.00040112558],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987229,0.00011913314,0.0005228479,0.00017180336,0.0002047852,0.00025854039],"domain_scores_gemma":[0.9990276,0.00027590006,0.00018185374,0.00019551213,0.00011215283,0.00020698867],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009359448,0.00015406536,0.0003869852,0.00006500505,0.00005401882,0.000023609218,0.000151941,0.00016837695,0.00019188563],"category_scores_gemma":[0.0005583029,0.00008937347,0.00017699611,0.0002519213,0.00004168504,0.000032404372,0.000040458046,0.00037322805,0.000024903311],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009275213,0.0002739483,0.03271919,0.000009734376,0.00004018975,0.00053905015,0.00007216836,0.0004133689,0.9548331,0.000008599949,0.00089850306,0.0009169568],"study_design_scores_gemma":[0.0023587262,0.001077023,0.73519427,0.00011697811,0.0000330646,0.00029212117,0.000093637354,0.0000585681,0.25080597,0.00028799748,0.0095390035,0.00014261277],"about_ca_topic_score_codex":0.000030715244,"about_ca_topic_score_gemma":0.000002373862,"teacher_disagreement_score":0.7040271,"about_ca_system_score_codex":0.00014213967,"about_ca_system_score_gemma":0.00009240613,"threshold_uncertainty_score":0.36445445},"labels":[],"label_agreement":null},{"id":"W2049017621","doi":"10.1007/s00109-013-1096-z","title":"Skeletal muscle, autophagy, and physical activity: the ménage à trois of metabolic regulation in health and disease","year":2013,"lang":"en","type":"review","venue":"Journal of Molecular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; York University","funders":"","keywords":"Autophagy; Cell biology; Homeostasis; Catabolism; Skeletal muscle; Biology; Anabolism; Lysosome; Flux (metallurgy); Autophagosome; Organelle; Metabolism; Chemistry; Biochemistry; Endocrinology","score_opus":0.026546772442868682,"score_gpt":0.3524484281087784,"score_spread":0.32590165566590973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049017621","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.054035287,0.942934,0.00015607096,0.0020253032,0.00008283736,0.0007290973,0.0000055731552,0.0000043029054,0.00002754015],"genre_scores_gemma":[0.04441938,0.9546203,0.00005877957,0.00038410467,0.000401967,0.000013322687,0.000010271071,0.00003522502,0.000056657962],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978498,0.00042423295,0.00074938755,0.00020424301,0.0005742573,0.00019805956],"domain_scores_gemma":[0.997648,0.00018039574,0.001178073,0.0003164952,0.00009573406,0.00058131875],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00063756295,0.0003032533,0.0022679192,0.00035297035,0.000033830456,0.000008052788,0.000118007585,0.000094076175,0.000029502477],"category_scores_gemma":[0.0003666167,0.0001593377,0.0003327738,0.00029769668,0.00029519267,0.00008495452,0.000041738873,0.0005630629,8.852279e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061188344,0.00023677884,0.000009261105,0.0068584117,0.00035711064,0.0002236974,0.000312375,6.1103066e-7,0.00027093588,0.00046037763,0.00014204883,0.99106723],"study_design_scores_gemma":[0.010683045,0.0033979255,0.050752405,0.07323088,0.009969507,0.0014554715,0.00030849985,0.00045460754,0.00011829265,0.003180049,0.8458029,0.0006464179],"about_ca_topic_score_codex":0.000028271576,"about_ca_topic_score_gemma":3.5358417e-7,"teacher_disagreement_score":0.99042076,"about_ca_system_score_codex":0.000039380957,"about_ca_system_score_gemma":0.0005902723,"threshold_uncertainty_score":0.64976025},"labels":[],"label_agreement":null},{"id":"W2049422105","doi":"10.1172/jci64180","title":"Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":142,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; BC Cancer Agency; Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"National Human Genome Research Institute; Ontario Ministry of Research and Innovation; Terry Fox Foundation; Stem Cell Network; Ontario Ministry of Health and Long-Term Care; Canadian Institutes of Health Research; Leukemia and Lymphoma Society; International Myeloma Foundation","keywords":"Myeloid leukemia; Lysosome; Biology; Progenitor cell; Leukemia; Cancer research; Cell biology; Stem cell; Haematopoiesis; Cathepsin; Vacuole; LAMP1; Immunology; Biochemistry","score_opus":0.05401678840932425,"score_gpt":0.3679316941701927,"score_spread":0.31391490576086845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049422105","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971987,0.00066246605,0.00030659026,0.00046905124,0.0010440379,0.00017519496,0.0000033749634,0.000016104208,0.00012445865],"genre_scores_gemma":[0.99282694,0.0006413746,0.0031422463,0.00064664945,0.002562057,0.000002646301,0.000012681805,0.000015835585,0.00014958293],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9982218,0.00015528871,0.0009950434,0.00010745475,0.00034230461,0.00017809606],"domain_scores_gemma":[0.99825186,0.00013018906,0.0006962906,0.00011572877,0.00018596601,0.00061994046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00091621745,0.00011799375,0.0003814947,0.000074728116,0.000050525985,0.000021151085,0.000059274294,0.00017884595,0.000060454156],"category_scores_gemma":[0.00024857206,0.000086584056,0.00020195445,0.000082684826,0.00016078104,0.00045966174,0.000019968349,0.0003713264,0.00001904967],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022071665,0.0008037381,0.7547228,0.0001658753,0.0014322333,0.00006134964,0.0010532459,0.000012828181,0.18293513,0.0007749554,0.0041090064,0.051721703],"study_design_scores_gemma":[0.0029557154,0.00097315235,0.8732306,0.00015416447,0.0008882548,0.00012931642,0.000046718396,0.00019009595,0.11653235,0.0018386734,0.0029212385,0.00013973528],"about_ca_topic_score_codex":0.0000018316563,"about_ca_topic_score_gemma":2.9674408e-7,"teacher_disagreement_score":0.118507825,"about_ca_system_score_codex":0.000049397535,"about_ca_system_score_gemma":0.00029475574,"threshold_uncertainty_score":0.35307953},"labels":[],"label_agreement":null},{"id":"W2049749131","doi":"10.1111/apha.12178","title":"Autophagy is altered in skeletal and cardiac muscle of spontaneously hypertensive rats","year":2013,"lang":"en","type":"article","venue":"Acta Physiologica","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Skeletal muscle; Internal medicine; Endocrinology; Autophagy; Cathepsin D; Messenger RNA; Chemistry; Spontaneously hypertensive rat; Cathepsin B; Medicine; Apoptosis; Blood pressure; Enzyme; Gene; Biochemistry","score_opus":0.011867673993418482,"score_gpt":0.24182139187786575,"score_spread":0.22995371788444727,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049749131","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99739677,0.0010164046,2.5853888e-7,0.00045980306,0.00007350443,0.00039534367,0.000013670373,0.000029642692,0.000614588],"genre_scores_gemma":[0.9975936,0.00047643436,0.000094165334,0.0014835114,0.0000987254,0.000033024247,0.000019647276,0.000011850107,0.00018908807],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991782,0.000049589366,0.000193841,0.00025251185,0.00011529323,0.00021060478],"domain_scores_gemma":[0.99940556,0.00008109153,0.000070412105,0.0002669266,0.00008072082,0.000095313924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004019837,0.00014213772,0.00046344314,0.000049537026,0.000027312079,0.0000057572643,0.00007154755,0.00010216606,0.0005407664],"category_scores_gemma":[0.000039017923,0.000101030135,0.00010309549,0.0000939742,0.00011447132,0.00007049818,0.00004561676,0.00012540967,0.000043741464],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007942819,0.0001815315,0.0005820109,0.00003664989,0.0000845522,0.00007966403,0.0003548119,6.300544e-7,0.98597014,0.00004738733,0.0025730217,0.010010191],"study_design_scores_gemma":[0.0008773619,0.0006403607,0.9605912,0.000047019978,0.000044190325,0.00002113085,0.00023362931,0.0001659791,0.034260526,0.00141036,0.0015510096,0.00015722697],"about_ca_topic_score_codex":0.00017822742,"about_ca_topic_score_gemma":6.112388e-7,"teacher_disagreement_score":0.9600092,"about_ca_system_score_codex":0.000015139583,"about_ca_system_score_gemma":0.000033248645,"threshold_uncertainty_score":0.5921013},"labels":[],"label_agreement":null},{"id":"W2050487309","doi":"10.3410/b2-88","title":"Closing in on the link between apoptosis and autophagy","year":2010,"lang":"en","type":"article","venue":"F1000 Biology Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Endoplasmic reticulum; Cell biology; Apoptosis; Regulator; Master regulator; Chemistry; Biology; Biochemistry; Transcription factor; Gene","score_opus":0.016577794814357515,"score_gpt":0.30042577584394636,"score_spread":0.28384798102958886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050487309","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902542,0.00022113978,0.000004684664,0.005373878,0.0003281095,0.00024396303,0.000002673495,0.000048333495,0.003523015],"genre_scores_gemma":[0.9977305,0.000043677195,0.000077059834,0.0011528378,0.00070722046,0.000022348373,0.00002425101,0.000013042007,0.00022907625],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9991603,0.00004642986,0.00026677983,0.0002666458,0.00006333166,0.00019650903],"domain_scores_gemma":[0.9992425,0.00016314203,0.00010140786,0.0003897253,0.000021524935,0.000081686245],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036211614,0.00011410965,0.00023533816,0.00007486875,0.00006913454,0.00000769065,0.00004416459,0.00020822312,0.00019866542],"category_scores_gemma":[0.00014538965,0.00006935492,0.000049894166,0.000093542796,0.00017504464,0.00001937366,0.000029154198,0.00039388885,0.00001315159],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000068415626,0.000052465282,0.8351706,0.000013866227,0.00010557806,0.00034637688,0.00023282573,1.8528797e-7,0.089397795,0.0021489628,0.00034963412,0.07211329],"study_design_scores_gemma":[0.00048689698,0.000258822,0.83341014,0.000047093425,0.00006083211,0.0002781546,0.000019926969,0.000011296665,0.12598978,0.0093451,0.029947907,0.00014406156],"about_ca_topic_score_codex":0.000040980576,"about_ca_topic_score_gemma":0.000004467468,"teacher_disagreement_score":0.071969226,"about_ca_system_score_codex":0.000010730907,"about_ca_system_score_gemma":0.000055975113,"threshold_uncertainty_score":0.28282118},"labels":[],"label_agreement":null},{"id":"W2050971602","doi":"10.4161/auto.28477","title":"Disruption of chaperone-mediated autophagy-dependent degradation of MEF2A by oxidative stress-induced lysosome destabilization","year":2014,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Universität Heidelberg; Jiangnan University; Natural Science Foundation of Jiangsu Province; Government of Jiangsu Province; University of Toronto; National Natural Science Foundation of China","keywords":"Biology; Cell biology; Autophagy; Oxidative stress; Lysosome; HDAC4; Proteasome; Transcription factor; Biochemistry; Histone; Histone deacetylase; Apoptosis","score_opus":0.01387541682179824,"score_gpt":0.2731110804032378,"score_spread":0.25923566358143957,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050971602","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99322873,0.0005941679,0.0045232326,0.00010849526,0.00019308497,0.0005956894,0.00011336616,0.00011869947,0.0005245154],"genre_scores_gemma":[0.9979767,0.00014376931,0.0002975918,0.00013633078,0.00007605765,0.0000442221,0.0008729514,0.000045223485,0.00040715068],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99782985,0.00018454585,0.0006984154,0.00040065692,0.0006007687,0.00028573364],"domain_scores_gemma":[0.99831027,0.0001942687,0.0005160588,0.000507307,0.00029801702,0.00017406583],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003147672,0.00026459442,0.00056424807,0.00020454919,0.00006468121,0.000010597361,0.00016134662,0.00020769204,0.0004153927],"category_scores_gemma":[0.00030789195,0.00023950118,0.00014293256,0.00037956276,0.00012496885,0.00027101787,0.000040396866,0.00015070639,0.000033836557],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025039236,0.000857333,0.004206085,0.00019746271,0.00015697282,0.0000047106337,0.0005842701,0.0000319499,0.9814846,0.0025472036,0.000065453714,0.009613556],"study_design_scores_gemma":[0.002570128,0.0007959729,0.059471767,0.00012643512,0.00017831827,0.000005949049,0.0001645068,0.003466714,0.9325201,0.0004130094,0.000095333875,0.00019179063],"about_ca_topic_score_codex":0.00009505581,"about_ca_topic_score_gemma":0.000009493975,"teacher_disagreement_score":0.05526568,"about_ca_system_score_codex":0.00009929228,"about_ca_system_score_gemma":0.00012302192,"threshold_uncertainty_score":0.9766575},"labels":[],"label_agreement":null},{"id":"W2051136206","doi":"10.4161/auto.26502","title":"Protective role of PARK2/Parkin in sepsis-induced cardiac contractile and mitochondrial dysfunction","year":2013,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":167,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Christie (Canada); McGill University Health Centre; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Institut National de la Santé et de la Recherche Médicale; Sanofi","keywords":"Mitophagy; Biology; Mitochondrion; Parkin; Autophagy; Cardiac function curve; mitochondrial fusion; Downregulation and upregulation; Cell biology; Mitochondrial DNA; Internal medicine; Biochemistry; Heart failure; Medicine","score_opus":0.006773885083172122,"score_gpt":0.23900290415380082,"score_spread":0.2322290190706287,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051136206","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950413,0.0011157185,0.000022236509,0.00015748842,0.00029742584,0.0013676668,0.0000072360554,0.0000465441,0.0019443602],"genre_scores_gemma":[0.9989522,0.000033326975,0.00010301107,0.00013281897,0.00021102744,0.00033693633,0.000009978841,0.000021039932,0.00019967812],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989683,0.00008323162,0.0002715267,0.00026573232,0.00018943376,0.00022176691],"domain_scores_gemma":[0.99938285,0.000067788176,0.00010863852,0.00023583695,0.000089492765,0.00011538547],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008459526,0.0001505269,0.0003988857,0.000115839466,0.00003443315,0.000013213362,0.000045511788,0.00014870676,0.00032767202],"category_scores_gemma":[0.000077160475,0.00013252188,0.000092893766,0.00015250429,0.000053055337,0.00016992437,0.00002101175,0.00019644568,0.000049492202],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005458587,0.00030442394,0.004011458,0.000049858765,0.000225175,0.000017649676,0.00075410126,0.0000022770114,0.9485153,0.00034269187,0.00037935821,0.044851836],"study_design_scores_gemma":[0.003134207,0.00043951624,0.55714256,0.00007175064,0.000091899085,0.000008851903,0.00037661102,0.0004003889,0.43419436,0.0027480125,0.0012383303,0.00015353243],"about_ca_topic_score_codex":0.0010257972,"about_ca_topic_score_gemma":0.000012197571,"teacher_disagreement_score":0.5531311,"about_ca_system_score_codex":0.00005344096,"about_ca_system_score_gemma":0.00009295945,"threshold_uncertainty_score":0.5404085},"labels":[],"label_agreement":null},{"id":"W2051609251","doi":"10.1016/j.bbamcr.2012.09.008","title":"Autophagy regulates trans fatty acid-mediated apoptosis in primary cardiac myofibroblasts","year":2012,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital; University of Manitoba; Children's Hospital Research Institute of Manitoba; Research Manitoba","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Manitoba Health Research Council","keywords":"ATG5; Autophagy; Apoptosis; Programmed cell death; Cell biology; Viability assay; FIS1; Chemistry; Biology; Molecular biology; Biochemistry; mitochondrial fusion; Gene","score_opus":0.023285417376002336,"score_gpt":0.3100465054552856,"score_spread":0.2867610880792833,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051609251","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9881589,0.002411203,0.00005221745,0.0015380452,0.00017082867,0.0013731548,0.00009370555,0.00017048448,0.0060314536],"genre_scores_gemma":[0.9959896,0.0010626168,0.00067114504,0.00068751234,0.0002838699,0.00020247676,0.00056515326,0.00016838168,0.00036921733],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9941506,0.00094313105,0.0006078134,0.0008889966,0.0016170614,0.0017924028],"domain_scores_gemma":[0.9971792,0.00030559508,0.00012450494,0.0012569537,0.0002419832,0.0008917795],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011547602,0.00055912364,0.0008666403,0.0007245821,0.00018239502,0.000086825945,0.0005482431,0.0004522182,0.00015011769],"category_scores_gemma":[0.00009730409,0.0005161827,0.0005706153,0.0016605927,0.0005023095,0.00029567874,0.00024540466,0.0011586045,0.00029143112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007258777,0.0016569928,0.000107123764,0.00033239587,0.00026140848,0.000056361398,0.0009411196,0.0000017019108,0.994026,0.0001008313,0.0009798451,0.0008103497],"study_design_scores_gemma":[0.0019616666,0.0004429373,0.041425254,0.00016773675,0.000106960564,0.0000038421776,0.00012395988,0.00006371678,0.95431304,0.000110596375,0.00081903924,0.00046123628],"about_ca_topic_score_codex":0.0000733782,"about_ca_topic_score_gemma":7.5385026e-7,"teacher_disagreement_score":0.04131813,"about_ca_system_score_codex":0.00035121856,"about_ca_system_score_gemma":0.0005730456,"threshold_uncertainty_score":0.999729},"labels":[],"label_agreement":null},{"id":"W2052779723","doi":"10.1016/j.cub.2012.06.001","title":"Interactions of Pathogenic Bacteria with Autophagy Systems","year":2012,"lang":"en","type":"review","venue":"Current Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":151,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Autophagy; Phagosome; Biology; Cell biology; Autophagosome; Intracellular parasite; Effector; Intracellular; Phagocytosis; ATG16L1; Microbiology; Biochemistry; Apoptosis","score_opus":0.11926602122394496,"score_gpt":0.41605921657949635,"score_spread":0.2967931953555514,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052779723","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00041438977,0.9953174,0.00007533248,0.0000027976673,0.0028667494,0.0007659821,0.00023826079,0.000047289723,0.00027177867],"genre_scores_gemma":[0.0016725139,0.995923,0.000026906839,0.000006632783,0.00076941925,0.00019846763,0.0011696615,0.00004087317,0.00019256445],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99862164,0.00019574487,0.00054870296,0.0002853109,0.00006948505,0.00027912183],"domain_scores_gemma":[0.99871093,0.0000909869,0.0004915643,0.0004774165,0.000075542855,0.00015353794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010058148,0.00032693497,0.0017081163,0.00019063953,0.000026993372,0.0000048279403,0.00013972736,0.00021452947,0.00048448346],"category_scores_gemma":[0.000011962103,0.00019649371,0.0003805481,0.00016486895,0.000121967416,0.000032035867,0.000041732394,0.00034177257,0.00016546107],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003530969,0.000297389,0.00004639183,0.015359033,0.0006401411,0.0000063399734,0.000022495255,1.6462826e-8,0.000052411317,0.00081484276,0.000113112066,0.9826125],"study_design_scores_gemma":[0.00030877884,0.00020489535,0.0000895194,0.0078979395,0.0023992197,0.000273618,0.0000046682135,0.0000010320058,0.0000085815755,0.0000056651375,0.98863566,0.00017042858],"about_ca_topic_score_codex":0.000004866032,"about_ca_topic_score_gemma":5.1021163e-7,"teacher_disagreement_score":0.9885225,"about_ca_system_score_codex":0.00007161743,"about_ca_system_score_gemma":0.00031965924,"threshold_uncertainty_score":0.8012781},"labels":[],"label_agreement":null},{"id":"W2052991849","doi":"10.1016/j.celrep.2014.07.061","title":"Autophagy Impairment in Muscle Induces Neuromuscular Junction Degeneration and Precocious Aging","year":2014,"lang":"en","type":"article","venue":"Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":413,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"European Research Council; Seventh Framework Programme; Ministero dell’Istruzione, dell’Università e della Ricerca; European Commission; Fondation Leducq; Association Française contre les Myopathies","keywords":"Autophagy; Neuromuscular junction; Cell biology; Oxidative stress; Biology; Myosin; Mitochondrion; Neuroscience; Endocrinology; Biochemistry; Apoptosis","score_opus":0.007628650223463423,"score_gpt":0.23436614888713322,"score_spread":0.2267374986636698,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052991849","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99708164,0.0006905253,0.00023708271,0.000093503906,0.0003180333,0.000267559,9.6059274e-8,0.00005812708,0.0012534148],"genre_scores_gemma":[0.99882483,0.000089273686,0.00011429249,0.00034389095,0.00016192763,0.00002444183,0.000014883548,0.000016318523,0.00041012088],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991443,0.000046107765,0.00024898862,0.00027000075,0.0001478765,0.00014271421],"domain_scores_gemma":[0.9995311,0.000014551877,0.00010462617,0.00022916432,0.00002602325,0.00009456332],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002680982,0.00010122101,0.00015161204,0.00008172019,0.000080132384,0.000014701583,0.000015232153,0.00006250919,0.00004227742],"category_scores_gemma":[0.000029846073,0.00009137583,0.00004180214,0.0000763122,0.000020327818,0.00007674099,0.000022430526,0.0000932609,0.0000035104688],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000101378006,0.0012313331,0.13222523,0.00048184805,0.00006406388,0.003253676,0.0036402368,0.0006224772,0.70759326,0.00008834311,0.00076473854,0.1499334],"study_design_scores_gemma":[0.00094756356,0.00027508853,0.7932609,0.00005548477,0.000060937997,0.00023690963,0.000050932573,0.0016703001,0.19877249,0.0004915617,0.004023153,0.00015468083],"about_ca_topic_score_codex":0.00004827712,"about_ca_topic_score_gemma":0.0000051431007,"teacher_disagreement_score":0.66103566,"about_ca_system_score_codex":0.000039985895,"about_ca_system_score_gemma":0.00003888969,"threshold_uncertainty_score":0.3726198},"labels":[],"label_agreement":null},{"id":"W2054088727","doi":"10.4161/15548627.2014.984270","title":"Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine","year":2014,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"Merck KGaA","keywords":"Autophagy; ATG5; BECN1; Biology; Cell biology; Autophagosome; Mitophagy; ATG12; Programmed cell death; Pharmacology; Biochemistry; Apoptosis","score_opus":0.013844700698053583,"score_gpt":0.2708248959565757,"score_spread":0.2569801952585221,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054088727","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928633,0.0003519286,0.00025653845,0.0022254514,0.0009831905,0.0006846525,0.0000075900552,0.00011250525,0.002514817],"genre_scores_gemma":[0.99374706,0.00009454535,0.0000351087,0.003703036,0.0003419044,0.00003606896,0.00001267297,0.000036106696,0.0019935092],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983954,0.00022511884,0.00036277872,0.00029313387,0.00044574795,0.00027784755],"domain_scores_gemma":[0.9985916,0.00014523856,0.00023961294,0.00084507524,0.00008416882,0.00009430403],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033164417,0.00021129732,0.00029425276,0.00007850384,0.00020077048,0.00002037008,0.00021205113,0.00009094327,0.00032001766],"category_scores_gemma":[0.000115912204,0.00012009737,0.00027003235,0.00041489766,0.00021555343,0.00011806787,0.000051068124,0.0003038705,0.00008681532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017842108,0.001725131,0.008478093,0.0006799582,0.0006418635,0.00007165055,0.0021497854,0.0005537576,0.867517,0.024863884,0.024787268,0.066747375],"study_design_scores_gemma":[0.0033032163,0.00027821356,0.29736897,0.00015925268,0.00021663852,0.000101642116,0.00008639297,0.0018239289,0.67372894,0.003556341,0.019184627,0.00019184817],"about_ca_topic_score_codex":0.000055043187,"about_ca_topic_score_gemma":0.000009527416,"teacher_disagreement_score":0.2888909,"about_ca_system_score_codex":0.000049825358,"about_ca_system_score_gemma":0.00010185287,"threshold_uncertainty_score":0.48974285},"labels":[],"label_agreement":null},{"id":"W2054193843","doi":"10.1371/journal.ppat.1003285","title":"Hepatitis C Virus Induces the Mitochondrial Translocation of Parkin and Subsequent Mitophagy","year":2013,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":198,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Diabetes and Digestive and Kidney Diseases; Johns Hopkins University; National Institute of Allergy and Infectious Diseases; University of California, San Diego; National Institutes of Health","keywords":"Mitophagy; Parkin; PINK1; Mitochondrion; Biology; Cell biology; Autophagy; Gene silencing; Immunoelectron microscopy; Hepatitis C virus; Virology; Molecular biology; Immunology; Virus; Biochemistry; Medicine; Apoptosis; Pathology; Antibody; Gene; Parkinson's disease","score_opus":0.018360674867152364,"score_gpt":0.24273460044012485,"score_spread":0.22437392557297248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054193843","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996004,0.0023879586,0.00006108425,0.00054319383,0.00012351057,0.0006111764,0.00003093794,0.000026638583,0.00021150064],"genre_scores_gemma":[0.9970618,0.0017981838,0.00034648785,0.0003310999,0.00023450537,0.00012221855,0.000020885089,0.000015889327,0.0000689388],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992136,0.00005966487,0.00021811931,0.00016052097,0.00020640851,0.0001416806],"domain_scores_gemma":[0.99945045,0.00005837251,0.000072996496,0.00024197064,0.00008520452,0.00009100456],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000045351633,0.00010814197,0.00019742908,0.000041397318,0.000057758447,0.000013003905,0.00006712222,0.00007008387,0.00028542985],"category_scores_gemma":[0.000032756136,0.00007153021,0.000070808324,0.00009535332,0.00010702006,0.00006376883,0.000010340247,0.00008671276,0.000033064956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051675608,0.00019640336,0.008678549,0.000039053997,0.0001344674,0.000011748986,0.00093836535,5.714792e-7,0.97531027,0.000114389615,0.00014075296,0.014383733],"study_design_scores_gemma":[0.0010216332,0.00021990936,0.24116573,0.00007419617,0.00016782973,0.000015503181,0.00009659976,0.00013668706,0.75580305,0.0009851652,0.00020700114,0.00010670396],"about_ca_topic_score_codex":0.00039582205,"about_ca_topic_score_gemma":0.00005186264,"teacher_disagreement_score":0.23248717,"about_ca_system_score_codex":0.000014233941,"about_ca_system_score_gemma":0.00005129729,"threshold_uncertainty_score":0.31252566},"labels":[],"label_agreement":null},{"id":"W2054729755","doi":"10.1016/j.bbalip.2013.03.007","title":"Autophagy in obesity and atherosclerosis: Interrelationships between cholesterol homeostasis, lipoprotein metabolism and autophagy in macrophages and other systems","year":2013,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Lipid metabolism; Homeostasis; Inflammation; Biology; Metabolic syndrome; Cholesterol; Cell biology; Mechanism (biology); Diabetes mellitus; Endocrinology; Immunology; Biochemistry; Apoptosis","score_opus":0.031672431518269144,"score_gpt":0.30560878822729093,"score_spread":0.2739363567090218,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054729755","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.51721364,0.48147455,0.000006696887,0.000039482522,0.000059203605,0.0010134645,0.0001401288,0.000021914517,0.00003091388],"genre_scores_gemma":[0.52366227,0.4757878,0.00007752677,0.00008670868,0.000085827356,0.00013548252,0.00008366396,0.000055719192,0.000025001444],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965213,0.0008213627,0.0010147556,0.0010084383,0.00016328218,0.00047084724],"domain_scores_gemma":[0.9984247,0.00018855082,0.00054391404,0.00053102156,0.00004089798,0.00027091935],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004123426,0.0007913225,0.0026977882,0.00054130616,0.000074103154,0.00007266124,0.00021829865,0.0009176913,0.000009641454],"category_scores_gemma":[0.000030511594,0.0006368878,0.00023624503,0.00032510783,0.00070737506,0.000102794205,0.00026734642,0.0007221098,0.0000045606726],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038771832,0.0025412198,0.0026800032,0.051858556,0.0038630536,0.00007637126,0.0034524016,5.9291415e-7,0.4402353,0.0019495361,0.000064369066,0.4928909],"study_design_scores_gemma":[0.02775181,0.00561213,0.32564038,0.0522513,0.013524049,0.00035829042,0.0010111306,0.00021331414,0.47876388,0.0018868889,0.08534482,0.007641988],"about_ca_topic_score_codex":0.00037323614,"about_ca_topic_score_gemma":0.000005698743,"teacher_disagreement_score":0.4852489,"about_ca_system_score_codex":0.000036513393,"about_ca_system_score_gemma":0.00011647107,"threshold_uncertainty_score":0.9996082},"labels":[],"label_agreement":null},{"id":"W2055074822","doi":"10.1074/jbc.m109.046789","title":"Oncogenic ras-induced Down-regulation of Autophagy Mediator Beclin-1 Is Required for Malignant Transformation of Intestinal Epithelial Cells","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Cancer Institute; Canadian Cancer Society Research Institute","keywords":"Cell biology; Autophagy; RHOA; Biology; Cell growth; Cancer cell; Malignant transformation; Apoptosis; Cancer research; Signal transduction; Cancer","score_opus":0.03346115085863084,"score_gpt":0.3007657981548096,"score_spread":0.26730464729617875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055074822","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99754786,0.0003153532,0.0012555417,0.0003927184,0.000080953694,0.00018956617,0.000050337992,0.0000101093365,0.00015756692],"genre_scores_gemma":[0.9982217,0.00012367792,0.0010597173,0.00016220708,0.0003638676,0.0000024212268,0.00002551867,0.0000057719,0.000035126905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99848944,0.000031682932,0.0009506938,0.00011806116,0.00025415237,0.00015599905],"domain_scores_gemma":[0.99847484,0.0001405964,0.0007780479,0.00012591378,0.00033937828,0.00014124233],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000434934,0.00013950134,0.0005149554,0.00004213776,0.00002721251,0.0000036022936,0.00012893416,0.00023569209,0.00028148617],"category_scores_gemma":[0.00018737915,0.0000915308,0.00041354628,0.00009668539,0.00007486854,0.000066532644,0.0000059248086,0.0001734661,0.00000160215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020508016,0.0003503876,0.000102064834,0.000118246455,0.000078380755,0.000008157793,0.00013793302,0.0000041046783,0.9909738,0.000029579527,0.00008339325,0.006063179],"study_design_scores_gemma":[0.002843758,0.0017585857,0.0069435495,0.00015514549,0.00013809177,0.00008761244,0.00007649399,0.00016002005,0.9856006,0.002029609,0.000120375895,0.00008615359],"about_ca_topic_score_codex":8.2625877e-7,"about_ca_topic_score_gemma":1.7669471e-8,"teacher_disagreement_score":0.006841485,"about_ca_system_score_codex":0.000051035804,"about_ca_system_score_gemma":0.00016687022,"threshold_uncertainty_score":0.37325177},"labels":[],"label_agreement":null},{"id":"W2056447191","doi":"10.1038/ncomms6276","title":"Autophagy supports genomic stability by degrading retrotransposon RNA","year":2014,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":149,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Stem Cell Network; Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute; J.P. Bickell Foundation","keywords":"Retrotransposon; Biology; RNA; Autophagy; Genetics; Genome; Gene; Transposable element","score_opus":0.017404146354238394,"score_gpt":0.30218170756571744,"score_spread":0.28477756121147907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056447191","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95726377,0.016321173,0.0005030226,0.006327492,0.00017871408,0.00049964956,0.00007045437,0.00027011707,0.018565593],"genre_scores_gemma":[0.9940555,0.0007246597,0.0026038005,0.001743561,0.0000703591,0.000040988045,0.0004254642,0.000029386467,0.00030624546],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989507,0.00016018855,0.00025843846,0.00022840021,0.0001816952,0.0002205712],"domain_scores_gemma":[0.99707973,0.00019489795,0.00008470524,0.0023608925,0.000100897385,0.00017885126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033193146,0.00014856634,0.00024091842,0.000060620023,0.0002577457,0.000018561914,0.00054489047,0.00028481233,0.00027607943],"category_scores_gemma":[0.00012067001,0.00013724728,0.00013541228,0.00019198125,0.00015487566,0.00007774556,0.00006954514,0.0009371865,0.000040033243],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004501492,0.0029159696,0.11656503,0.0002360599,0.0006801566,0.000016126978,0.0021896122,0.0000033312378,0.70858335,0.05834063,0.05202537,0.057994217],"study_design_scores_gemma":[0.0026937823,0.00031442774,0.30240625,0.000110845314,0.00038819053,0.000041383286,0.00011543386,0.0021183689,0.12258144,0.0030178158,0.56567043,0.0005416147],"about_ca_topic_score_codex":0.000019460147,"about_ca_topic_score_gemma":0.000028475528,"teacher_disagreement_score":0.58600193,"about_ca_system_score_codex":0.000113047216,"about_ca_system_score_gemma":0.00008902855,"threshold_uncertainty_score":0.5596782},"labels":[],"label_agreement":null},{"id":"W2057731584","doi":"10.1152/ajpcell.00380.2014","title":"Role of PGC-1α during acute exercise-induced autophagy and mitophagy in skeletal muscle","year":2015,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":269,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Mitophagy; Autophagy; Mitochondrial biogenesis; Coactivator; Mitochondrion; Skeletal muscle; NRF1; Biology; Endocrinology; Cell biology; Internal medicine; Transcription factor; Biochemistry; Medicine; Apoptosis; Gene","score_opus":0.0077297985030382824,"score_gpt":0.25757711842626996,"score_spread":0.24984731992323167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057731584","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99744314,0.0019196685,0.000001971192,0.00007781018,0.00018777291,0.0001872437,0.0000071987333,0.000018493238,0.00015668948],"genre_scores_gemma":[0.9984512,0.0004933845,0.00040619337,0.00025270248,0.00030631138,0.000009489107,0.000007210968,0.000038463302,0.000035090656],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99799764,0.00022314623,0.00074531557,0.00035747638,0.00021405889,0.0004623389],"domain_scores_gemma":[0.9981272,0.000097774806,0.00084508414,0.00036697512,0.0002267239,0.00033619042],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018508166,0.00030033305,0.0014100567,0.0003301469,0.00003949726,0.0000039584575,0.00025704113,0.0001327996,0.000054455726],"category_scores_gemma":[0.00003766882,0.00024843184,0.00026088484,0.0003529684,0.00061418355,0.00014194672,0.00010741705,0.00047531206,0.0000132232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014477842,0.0006119723,0.00032978161,0.000051284966,0.00020470611,0.00006282929,0.00077863445,0.00007203317,0.9915073,0.000016001357,0.000044506945,0.004873199],"study_design_scores_gemma":[0.0058579785,0.0042962986,0.47124213,0.00010846434,0.00019321594,0.00016682335,0.0016605239,0.00014516446,0.5137394,0.0022122792,0.00012405192,0.00025365886],"about_ca_topic_score_codex":0.00009150707,"about_ca_topic_score_gemma":0.0000016515373,"teacher_disagreement_score":0.47776785,"about_ca_system_score_codex":0.00006732189,"about_ca_system_score_gemma":0.0002743355,"threshold_uncertainty_score":0.9999968},"labels":[],"label_agreement":null},{"id":"W2057813271","doi":"10.4161/auto.19652","title":"Dual roles of Atg8−PE deconjugation by Atg4 in autophagy","year":2012,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":239,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"National Institutes of Health; National Key Research and Development Program of China; Chinese Academy of Agricultural Sciences; National Institute of General Medical Sciences; National Natural Science Foundation of China","keywords":"ATG8; Autophagy; Lipid-anchored protein; Cell biology; Autophagosome; Biology; Ubiquitin; Cysteine protease; Phosphatidylethanolamine; Membrane; Intracellular; Protease; Biochemistry; Enzyme; Phospholipid; Gene","score_opus":0.010738583143412318,"score_gpt":0.28340480951685887,"score_spread":0.27266622637344656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057813271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9864706,0.008672395,0.00009622705,0.0002077672,0.0002964813,0.00034149684,0.000027551545,0.00009620162,0.0037912913],"genre_scores_gemma":[0.99701524,0.00018661539,0.0002932618,0.0007122544,0.00025497022,0.000038137856,0.00009792762,0.000039285085,0.0013623134],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99836755,0.00007750379,0.0005006623,0.00024849965,0.00032377214,0.00048200792],"domain_scores_gemma":[0.9990559,0.00009205441,0.00016371312,0.00038990387,0.000061980725,0.00023640724],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00031511637,0.00021787429,0.00044647546,0.00017735988,0.000041577016,0.000008667146,0.00010700777,0.00018208555,0.0010507866],"category_scores_gemma":[0.000074307325,0.00020251458,0.00013882192,0.00028634226,0.00010265383,0.0002731609,0.00004136418,0.00018325959,0.00017585405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014956425,0.0062732473,0.19407934,0.00058095093,0.0007480743,0.0002520443,0.008009403,0.000042624943,0.6007285,0.021994144,0.022474114,0.14332193],"study_design_scores_gemma":[0.0036952416,0.00029214076,0.4322494,0.00010237414,0.00010374663,0.00005607959,0.00018310775,0.0003580223,0.5485723,0.00081493496,0.013291431,0.00028123008],"about_ca_topic_score_codex":0.000069378824,"about_ca_topic_score_gemma":0.00000985152,"teacher_disagreement_score":0.23817004,"about_ca_system_score_codex":0.000088415436,"about_ca_system_score_gemma":0.00010710089,"threshold_uncertainty_score":0.9998624},"labels":[],"label_agreement":null},{"id":"W2058376595","doi":"10.1016/j.bcp.2014.12.014","title":"Disulfiram-induced cytotoxicity and endo-lysosomal sequestration of zinc in breast cancer cells","year":2015,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Cancer Research Wales; Cancer Research UK; Wellcome Trust; Wellcome","keywords":"Disulfiram; Pharmacology; Chemistry; Cytotoxicity; Cancer; Zinc; Cancer cell; Extracellular; Cancer research; Biochemistry; Medicine; Internal medicine; In vitro","score_opus":0.03242089441210948,"score_gpt":0.34374274709118474,"score_spread":0.31132185267907525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058376595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99781615,0.000668251,0.0000041948824,0.0008698926,0.0001478769,0.0002577519,0.000038856946,0.000022067152,0.00017494523],"genre_scores_gemma":[0.99873364,0.00013602363,0.000050832376,0.000766654,0.00023459079,0.000034525558,0.000014624512,0.000010013159,0.000019094337],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925286,0.000048424146,0.00021384518,0.00019571841,0.00011418412,0.00017499026],"domain_scores_gemma":[0.9995483,0.000031291016,0.00006354376,0.00007772419,0.000063202744,0.00021591416],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000087205815,0.00010701606,0.00023907737,0.000051782496,0.00001007909,0.0000024318524,0.000052082727,0.00013020894,0.00015566556],"category_scores_gemma":[0.00000929931,0.00009501143,0.000035101733,0.00010648974,0.00011334905,0.00004119509,0.000031583764,0.00014439586,0.000004875681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008515424,0.00032287845,0.0050988523,0.00004059815,0.000043623793,0.000039243598,0.00008084464,0.0000011544064,0.9884675,0.00002737507,0.004887431,0.0001389676],"study_design_scores_gemma":[0.0032804657,0.000117767675,0.02771725,0.000019986946,0.00006943938,0.000028685086,0.000018633862,0.00020339228,0.96830106,0.00011088254,0.00005067144,0.00008177793],"about_ca_topic_score_codex":0.000104949555,"about_ca_topic_score_gemma":8.0011836e-7,"teacher_disagreement_score":0.022618398,"about_ca_system_score_codex":0.00008277354,"about_ca_system_score_gemma":0.00018277188,"threshold_uncertainty_score":0.3874454},"labels":[],"label_agreement":null},{"id":"W2058422567","doi":"10.4161/auto.2825","title":"Autophagy Recognizes Intracellular Salmonella enterica serovar Typhimurium in Damaged Vacuoles","year":2006,"lang":"en","type":"review","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Vacuole; Biology; Salmonella enterica; Autophagy; Intracellular; Intracellular parasite; Cytosol; Microbiology; Population; Salmonella; Cell biology; Pathogen; Bacteria; Biochemistry; Cytoplasm; Apoptosis; Genetics; Enzyme","score_opus":0.04153646797617262,"score_gpt":0.35144954838864084,"score_spread":0.30991308041246823,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058422567","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017867535,0.98969954,0.00006972547,0.00006536574,0.0009011959,0.002027145,0.00012315702,0.00045234594,0.0048747417],"genre_scores_gemma":[0.00096419576,0.9851858,0.0008161243,0.00037486956,0.0009970001,0.0003470573,0.001322069,0.00034485076,0.009648031],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.994406,0.0005460578,0.0018849274,0.001401939,0.0006356118,0.001125462],"domain_scores_gemma":[0.9969249,0.00032008797,0.00071794394,0.0015099021,0.0001220981,0.00040506988],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.0005368381,0.0013260081,0.0041747787,0.0009347795,0.0001313802,0.00009005498,0.0006701738,0.0011154156,0.0013777752],"category_scores_gemma":[0.000114228205,0.0011433733,0.0012990367,0.0011674936,0.00021326506,0.00016555011,0.00020861582,0.0014351503,0.001353835],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012048889,0.001172192,0.00002645755,0.01315839,0.000734321,0.004803218,0.00010337439,0.000002160402,0.0001282399,0.00017254762,0.0051278844,0.9744507],"study_design_scores_gemma":[0.0020460854,0.00028548023,0.0005819093,0.008910941,0.0016956184,0.00040195556,0.000016802884,0.000046964935,0.00086503284,0.00032514462,0.98380953,0.0010145514],"about_ca_topic_score_codex":0.00015011022,"about_ca_topic_score_gemma":0.000013518509,"teacher_disagreement_score":0.9786816,"about_ca_system_score_codex":0.0004488197,"about_ca_system_score_gemma":0.00086511095,"threshold_uncertainty_score":0.9999491},"labels":[],"label_agreement":null},{"id":"W2058532554","doi":"10.1074/jbc.m114.614925","title":"The E3 Ubiquitin Ligase Parkin Is Recruited to the 26 S Proteasome via the Proteasomal Ubiquitin Receptor Rpn13","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Parkin; Ubiquitin ligase; Ubiquitin; Mitophagy; Proteasome; Cell biology; Chemistry; Biochemistry; Biology; Parkinson's disease; Gene; Medicine; Internal medicine","score_opus":0.05029248006527643,"score_gpt":0.3036910209277611,"score_spread":0.2533985408624847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058532554","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94698894,0.0027501998,0.000053523137,0.04805043,0.00017186043,0.0009669094,0.000017139217,0.000047116984,0.0009538748],"genre_scores_gemma":[0.9903444,0.00023396173,0.00018883772,0.005265312,0.002380062,0.00015422162,0.0000061768437,0.000026048912,0.0014009906],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978111,0.0002365474,0.0006794006,0.00024502436,0.00058456446,0.00044336676],"domain_scores_gemma":[0.9976989,0.0003051078,0.0004960364,0.00053420337,0.00042477954,0.00054097356],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018343137,0.00026312587,0.00039611667,0.000018074337,0.00028424716,0.00007997307,0.0007474344,0.00024475926,0.0004291855],"category_scores_gemma":[0.0015075281,0.00009599397,0.00033536315,0.00027008652,0.00031599443,0.000049094044,0.00013940038,0.00090432266,0.00010005745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009310661,0.00097511517,0.0029367306,0.0000925426,0.0007960187,0.0003745872,0.0015888645,0.000007679651,0.78183293,0.00007287125,0.14647864,0.055533383],"study_design_scores_gemma":[0.0014212203,0.0009441951,0.0028139008,0.0001717111,0.00008738425,0.00062390766,0.00086629996,0.000025286017,0.68771297,0.0010488115,0.30409688,0.00018745939],"about_ca_topic_score_codex":0.000004808783,"about_ca_topic_score_gemma":3.9834006e-7,"teacher_disagreement_score":0.15761824,"about_ca_system_score_codex":0.00013100675,"about_ca_system_score_gemma":0.00033891978,"threshold_uncertainty_score":0.46992803},"labels":[],"label_agreement":null},{"id":"W2058563691","doi":"10.1158/1535-7163.targ-13-b235","title":"Abstract B235: The role of eIF4E in promoting melanoma cell proliferation and maintaining acquired resistance to vemurafenib in melanoma.","year":2013,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; Montreal General Hospital; McGill University","funders":"","keywords":"Vemurafenib; Melanoma; Cancer research; Cell growth; Gene silencing; Cell culture; EIF4E; Biology; Autophagy; Carcinogenesis; Cancer; Apoptosis; Translation (biology); Messenger RNA; Genetics; Gene","score_opus":0.011321510108316304,"score_gpt":0.2647805564617168,"score_spread":0.2534590463534005,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058563691","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98818994,0.008153167,0.00005383619,0.0015621672,0.000029070907,0.001051673,0.000004254391,0.000015941445,0.0009399514],"genre_scores_gemma":[0.99765325,0.00018190597,0.00027642524,0.0015101566,0.000035795434,0.00023790142,0.0000053195135,0.000031893385,0.00006737105],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887425,0.000067412766,0.00033402257,0.00023817063,0.00022001757,0.00026614984],"domain_scores_gemma":[0.9994426,0.00003739049,0.00010938282,0.00026943348,0.000070776805,0.00007046662],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021177078,0.00015738126,0.0002420296,0.00010729813,0.00003961124,0.000026599831,0.000113926166,0.000083331775,0.000050190756],"category_scores_gemma":[0.000009546921,0.00012270319,0.000042744545,0.0002659478,0.000050514183,0.00006912549,0.000027854841,0.0001333296,0.0000042361894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004608709,0.0002251057,0.0801363,0.00013848126,0.00010544819,0.000055804863,0.0099134445,0.00014219264,0.86932063,0.00037311626,0.000007282997,0.039121293],"study_design_scores_gemma":[0.0022140313,0.00020635029,0.31966645,0.00040297132,0.000066544955,0.000004208267,0.0013150035,0.0017281466,0.6701272,0.0026762187,0.0013466269,0.00024621878],"about_ca_topic_score_codex":0.00019320812,"about_ca_topic_score_gemma":0.00017147852,"teacher_disagreement_score":0.23953015,"about_ca_system_score_codex":0.00009247483,"about_ca_system_score_gemma":0.00011485327,"threshold_uncertainty_score":0.50036913},"labels":[],"label_agreement":null},{"id":"W2058742845","doi":"10.4161/auto.27750","title":"The emerging potential of autophagy-based therapies in the treatment of cystic fibrosis lung infections","year":2014,"lang":"en","type":"letter","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Izaak Walton Killam Health Centre; Dalhousie University","funders":"","keywords":"Cystic fibrosis; Autophagy; Biology; Cystic fibrosis transmembrane conductance regulator; Inflammation; Immunology; Mucus; Pathogen; Lung; Antibiotics; Microbiology; Medicine; Internal medicine","score_opus":0.010409856569207659,"score_gpt":0.27630672605473844,"score_spread":0.26589686948553076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058742845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.63346076,0.048851427,0.0021200764,0.3053768,0.0026657463,0.005089301,0.00028478267,0.00031298102,0.0018381163],"genre_scores_gemma":[0.9383823,0.0011319204,0.00014779762,0.05698115,0.0016449421,0.00038955116,0.00027618854,0.00010010346,0.0009459966],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99732083,0.00044596393,0.00076535513,0.00037777735,0.00061830436,0.0004717941],"domain_scores_gemma":[0.9972438,0.0009717836,0.00049179414,0.001120684,0.00012501205,0.000046904017],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003157752,0.00045752822,0.00083317567,0.00029232382,0.00022428707,0.000033540116,0.0003729993,0.0004343373,0.0002169701],"category_scores_gemma":[0.00004721829,0.0002527866,0.0006982554,0.00039206343,0.0003536838,0.00004176756,0.000017670103,0.0005431195,0.000013288288],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037287206,0.013833149,0.006930099,0.0073771686,0.014768143,0.0048488984,0.021834487,0.003693844,0.036018737,0.0034008592,0.770018,0.1135479],"study_design_scores_gemma":[0.009562731,0.005254341,0.044256773,0.00096121454,0.0031189527,0.00013453703,0.00033023336,0.0073721097,0.026736703,0.001650758,0.8997801,0.00084155414],"about_ca_topic_score_codex":0.00028573122,"about_ca_topic_score_gemma":0.000012539049,"teacher_disagreement_score":0.30492157,"about_ca_system_score_codex":0.0001392217,"about_ca_system_score_gemma":0.00030473113,"threshold_uncertainty_score":0.99999243},"labels":[],"label_agreement":null},{"id":"W2059316279","doi":"10.4161/auto.26378","title":"Autophagy","year":2013,"lang":"hu","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia; University of Victoria; Simon Fraser University; Terry Fox Research Institute; BC Cancer Agency","funders":"","keywords":"Autophagy; Context (archaeology); Biology; Multidisciplinary approach; Political science; Genetics; Apoptosis","score_opus":0.007257610664963191,"score_gpt":0.24263401965041007,"score_spread":0.23537640898544687,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059316279","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8658113,0.03948552,0.00028858354,0.0027916888,0.0043425667,0.0023564007,0.00006266841,0.0008426744,0.084018596],"genre_scores_gemma":[0.90972537,0.0013015199,0.0004431841,0.0071543525,0.002219341,0.00024383777,0.00008555616,0.00018736941,0.07863947],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99520284,0.00022423502,0.0010419703,0.001079229,0.00087415834,0.0015775637],"domain_scores_gemma":[0.99630415,0.00023457562,0.0003313466,0.0016606398,0.00033327812,0.0011359862],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0003004623,0.00085187604,0.001110715,0.00032921656,0.00034123124,0.00023113436,0.0006421275,0.000629181,0.087252714],"category_scores_gemma":[0.00016180133,0.00078439567,0.0006236566,0.000640945,0.00041665832,0.0005930458,0.00021257374,0.0007862886,0.06715137],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055507594,0.0055625,0.0041377433,0.0014407597,0.0045120916,0.0035762761,0.0049605155,0.000045867026,0.094890065,0.0463405,0.376771,0.4572076],"study_design_scores_gemma":[0.013532251,0.0023584436,0.5189742,0.00092662557,0.0015596333,0.00043547287,0.0009934432,0.009001001,0.19138204,0.017704887,0.2403985,0.0027335347],"about_ca_topic_score_codex":0.0007148214,"about_ca_topic_score_gemma":0.000003888911,"teacher_disagreement_score":0.51483643,"about_ca_system_score_codex":0.00025601874,"about_ca_system_score_gemma":0.0006200219,"threshold_uncertainty_score":0.9994607},"labels":[],"label_agreement":null},{"id":"W2060290354","doi":"10.1038/cdd.2010.104","title":"Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy","year":2010,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institutes of Health; National Cancer Institute; Institute of Genetics; School of Medicine, Stanford University; University of Pennsylvania","keywords":"Autophagy; Unfolded protein response; Cell biology; Sphingosine kinase; Endoplasmic reticulum; Sphingosine; Ceramide; Sphingosine kinase 1; Protein kinase A; Protein kinase B; Kinase; Intracellular; Chemistry; Biology; Signal transduction; Sphingosine-1-phosphate; Biochemistry; Apoptosis; Receptor","score_opus":0.009165407584468004,"score_gpt":0.23800276396395406,"score_spread":0.22883735637948605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060290354","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966882,0.0007932881,0.00014606035,0.000116848496,0.00046086762,0.00028875744,0.000012587744,0.00013370845,0.0013596974],"genre_scores_gemma":[0.99748385,0.00015857196,0.00022743987,0.00028795324,0.00021841805,0.000019134939,0.00019602946,0.000030835563,0.0013777779],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989787,0.000016551488,0.00022121704,0.0003212454,0.00020134276,0.00026096866],"domain_scores_gemma":[0.99922496,0.000033163822,0.00010311448,0.00031005984,0.00006548174,0.00026319304],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006244566,0.00020861419,0.00024062817,0.00008410058,0.0001382086,0.00006201591,0.000064202664,0.00016932552,0.00061906094],"category_scores_gemma":[0.000023123313,0.0001731499,0.00009110965,0.000093831295,0.00003146587,0.00013177756,0.000028263903,0.00022908126,0.000045505945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003211795,0.00059542764,0.06749163,0.00017112485,0.00009566752,0.000044473116,0.000348874,0.00000326606,0.9198295,0.0015919425,0.00024006008,0.0092668515],"study_design_scores_gemma":[0.001628746,0.000097490476,0.38544366,0.000025063746,0.00012098596,0.000008132428,0.000011808675,0.0026632287,0.6086837,0.0009388461,0.00023975219,0.00013858617],"about_ca_topic_score_codex":0.000044895976,"about_ca_topic_score_gemma":0.000006882293,"teacher_disagreement_score":0.31795204,"about_ca_system_score_codex":0.000015145807,"about_ca_system_score_gemma":0.0000447265,"threshold_uncertainty_score":0.70608485},"labels":[],"label_agreement":null},{"id":"W2060764911","doi":"10.1007/s00401-015-1393-4","title":"X-linked myopathy with excessive autophagy: a failure of self-eating","year":2015,"lang":"en","type":"review","venue":"Acta Neuropathologica","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Autophagy; Myopathy; Vacuole; Lysosome; Bafilomycin; Sarcolemma; Biology; Pathology; Muscle biopsy; Skeletal muscle; Cell biology; Medicine; Endocrinology; Biopsy; Biochemistry; Cytoplasm","score_opus":0.04579834020418828,"score_gpt":0.3301656460647077,"score_spread":0.28436730586051945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060764911","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010520465,0.98481184,0.000008860696,0.00004719682,0.00014227939,0.0015881406,0.00007930384,0.000415007,0.0023868836],"genre_scores_gemma":[0.009945134,0.9871838,0.0014321911,0.00030136033,0.00032902954,0.00018882923,0.00015581715,0.0001538654,0.00030994706],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967623,0.0005292546,0.00083608093,0.0008326352,0.000567095,0.00047263657],"domain_scores_gemma":[0.99696517,0.00021791384,0.0011360941,0.0010704262,0.00028646603,0.00032392592],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036166798,0.0007573628,0.0030527,0.0002448583,0.00008841192,0.000027367518,0.00046625384,0.00047919512,0.00012969234],"category_scores_gemma":[0.00023996974,0.00045040128,0.0005516622,0.0006169241,0.0001902316,0.00009616271,0.000168044,0.00089136476,0.00007107953],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000432669,0.00206133,0.00025550753,0.03794648,0.0010759521,0.028315822,0.0011334381,0.0000010167307,0.00041395184,0.0001902592,0.002235878,0.9259377],"study_design_scores_gemma":[0.0014991066,0.0029749677,0.0005702182,0.011316021,0.0040135076,0.0035183427,0.000067526744,0.000007810439,0.00003774315,0.00005331466,0.97528106,0.00066037965],"about_ca_topic_score_codex":0.0000014918937,"about_ca_topic_score_gemma":2.0159102e-7,"teacher_disagreement_score":0.9730452,"about_ca_system_score_codex":0.00008014536,"about_ca_system_score_gemma":0.0008588037,"threshold_uncertainty_score":0.9997948},"labels":[],"label_agreement":null},{"id":"W2060792177","doi":"10.1016/j.exger.2009.11.002","title":"Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise","year":2009,"lang":"en","type":"article","venue":"Experimental Gerontology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":390,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"National Institute on Aging; University of Florida","keywords":"Autophagy; Sarcopenia; Apoptosis; Skeletal muscle; Calorie restriction; Programmed cell death; Cell biology; Biology; Endocrinology; Downregulation and upregulation; Senescence; Internal medicine; Protein degradation; Gene; Medicine; Biochemistry","score_opus":0.011053308451443688,"score_gpt":0.2870855064397359,"score_spread":0.2760321979882922,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060792177","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97437733,0.024656283,0.000025268277,0.00012492118,0.00017911868,0.0003001374,0.0000010273919,0.000058845115,0.00027703523],"genre_scores_gemma":[0.99879885,0.0006517756,0.00016797452,0.00015758935,0.00009422914,0.000024093384,0.0000065844174,0.000012499602,0.00008641945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918014,0.000033951514,0.0001945778,0.00026571436,0.00010874792,0.00021686885],"domain_scores_gemma":[0.9995324,0.000031402713,0.00006809461,0.00016045726,0.000015048405,0.00019257753],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003225864,0.0001533198,0.00033923652,0.0000841636,0.000080259364,0.000007222549,0.00003663323,0.000105146406,0.000038224673],"category_scores_gemma":[0.00001825856,0.00014594592,0.00005261045,0.00006321766,0.00012194012,0.00009427085,0.000028086522,0.000090025605,0.00000224436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005149621,0.0008032674,0.007994101,0.00023281973,0.00011183567,0.00018790565,0.0027038308,6.014424e-7,0.9737363,0.00056099077,0.000109324836,0.013044102],"study_design_scores_gemma":[0.0022490772,0.00061187276,0.47439426,0.00006235086,0.00005410593,0.000016837817,0.00021846121,0.00001125084,0.5222133,0.00004580979,0.000028722496,0.000093997456],"about_ca_topic_score_codex":0.00005307965,"about_ca_topic_score_gemma":8.0620777e-7,"teacher_disagreement_score":0.46640015,"about_ca_system_score_codex":0.00003851145,"about_ca_system_score_gemma":0.000021647294,"threshold_uncertainty_score":0.5951502},"labels":[],"label_agreement":null},{"id":"W2061547059","doi":"10.1038/bjc.2015.17","title":"RETRACTED ARTICLE: Effect of pantoprazole to enhance activity of docetaxel against human tumour xenografts by inhibiting autophagy","year":2015,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":54,"is_retracted":true,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Docetaxel; Pantoprazole; Pharmacology; Apoptosis; Chemistry; Chemotherapy; Cancer research; Medicine; Internal medicine; Biochemistry","score_opus":0.010968436238068697,"score_gpt":0.3358028560096915,"score_spread":0.3248344197716228,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061547059","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98895574,0.00986086,0.000062551844,0.00014085922,0.00019746242,0.00022717332,0.000046128098,0.000015485097,0.00049373205],"genre_scores_gemma":[0.9986728,0.0004765267,0.000088543406,0.00020681652,0.00039349688,0.000008235508,0.000003171268,0.000026630025,0.00012381496],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982355,0.00012610045,0.000602601,0.00015232437,0.000627717,0.00025574106],"domain_scores_gemma":[0.9982412,0.000063862244,0.00067434716,0.00012299247,0.00051958027,0.00037801036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000732068,0.00014343199,0.0006553595,0.00009852381,0.000045613768,0.000020612559,0.00013226597,0.00010399857,0.00008382082],"category_scores_gemma":[0.00028787332,0.00014285262,0.00018444342,0.00028191882,0.00008405226,0.00022156771,0.000028982411,0.00041592805,0.0000021074602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008317253,0.00029166276,0.0036759581,0.00013095562,0.00020130724,0.0003218921,0.00018149633,0.000027345928,0.87551546,0.0000015284339,0.0036975006,0.11512317],"study_design_scores_gemma":[0.002862173,0.0010349195,0.058944423,0.0015961366,0.00013384785,0.00020247737,0.000029552059,0.000023368257,0.93439305,0.000020190853,0.00064427673,0.00011558573],"about_ca_topic_score_codex":0.00029811103,"about_ca_topic_score_gemma":0.00004530676,"teacher_disagreement_score":0.11500758,"about_ca_system_score_codex":0.00011251464,"about_ca_system_score_gemma":0.00023747314,"threshold_uncertainty_score":0.58253604},"labels":[],"label_agreement":null},{"id":"W2062161748","doi":"10.1016/j.freeradbiomed.2012.07.011","title":"Reactive oxygen species regulation of autophagy in cancer: Implications for cancer treatment","year":2012,"lang":"en","type":"review","venue":"Free Radical Biology and Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":153,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Manitoba; University of Manitoba","funders":"","keywords":"Autophagy; Oxidative stress; Reactive oxygen species; Cell biology; Carcinogenesis; Intracellular; Programmed cell death; Cancer cell; Biology; Downregulation and upregulation; Cancer; Chemistry; Biochemistry; Apoptosis; Genetics","score_opus":0.11242250183735049,"score_gpt":0.43530407113942593,"score_spread":0.32288156930207546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062161748","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00055886817,0.9943765,0.0000534916,0.0023877686,0.00025556659,0.0014594828,0.00058062276,0.000018743964,0.00030899287],"genre_scores_gemma":[0.0017232226,0.9940465,0.00008471962,0.00014912708,0.0011870983,0.0011460802,0.0009586713,0.00002212479,0.00068245083],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987524,0.0000824355,0.0005335901,0.00031801092,0.00005757321,0.00025596458],"domain_scores_gemma":[0.9987602,0.00037008506,0.00029299545,0.00034181174,0.00005340675,0.00018148399],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016250058,0.00027187399,0.0017255443,0.00020075828,0.000050747287,8.0338833e-7,0.00009741773,0.0004334168,0.00032081653],"category_scores_gemma":[0.00009458288,0.00016236893,0.00017207552,0.00017861112,0.0005637452,0.000022275164,0.00002048082,0.00015268628,8.938508e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013466136,0.00021095683,0.0009673553,0.0022691647,0.00058607326,0.0000013432996,0.00014133251,3.9974342e-8,0.00028070307,0.008478309,0.00067712256,0.98625296],"study_design_scores_gemma":[0.0023121375,0.00068891,0.026876735,0.0033080352,0.0024631156,0.000020241354,0.000010029432,0.0000019927606,0.000069209294,0.0021439518,0.9619794,0.00012626732],"about_ca_topic_score_codex":0.0003750907,"about_ca_topic_score_gemma":0.00009225323,"teacher_disagreement_score":0.98612666,"about_ca_system_score_codex":0.00025245568,"about_ca_system_score_gemma":0.00037442116,"threshold_uncertainty_score":0.6621213},"labels":[],"label_agreement":null},{"id":"W2063048095","doi":"10.1016/j.bbrc.2013.10.117","title":"Context-dependent role of ATG4B as target for autophagy inhibition in prostate cancer therapy","year":2013,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; Sunnybrook Hospital","funders":"Prostate Cancer Canada","keywords":"Prostate cancer; Autophagy; Cancer research; In vivo; Context (archaeology); In vitro; Proteases; Cancer therapy; Cancer; Cytotoxic T cell; Cancer cell; Biology; Chemistry; Medicine; Internal medicine; Biochemistry; Apoptosis; Enzyme; Genetics","score_opus":0.05373807694956115,"score_gpt":0.3956858868379279,"score_spread":0.3419478098883667,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063048095","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98047537,0.012856784,0.0000050410795,0.0049383678,0.0000066463635,0.001296995,0.000047468493,0.000018104764,0.0003552421],"genre_scores_gemma":[0.9917685,0.006068409,0.00037022887,0.00018577935,0.00004454307,0.0012271935,0.00008771633,0.000013027228,0.00023460179],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895173,0.000095086725,0.00022921864,0.00020510667,0.00025750385,0.00026133156],"domain_scores_gemma":[0.9985577,0.00031196018,0.00003885613,0.00054919027,0.00037214946,0.00017017142],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021513845,0.00009658712,0.00022782006,0.00008896179,0.000097852986,0.000020103535,0.00016722424,0.000075518175,0.000105957784],"category_scores_gemma":[0.00012939078,0.00007368486,0.000087661225,0.00024972457,0.00052488,0.000071148694,0.00012726987,0.00027562573,0.000019129835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003101134,0.0010081095,0.00027975737,0.000043764438,0.000049353243,5.9463736e-7,0.00020525073,1.1427191e-7,0.95171934,0.0044922773,0.0003622963,0.041529026],"study_design_scores_gemma":[0.0018792108,0.000536035,0.005709306,0.00011816827,0.000009752053,0.0000017397992,0.00028778866,0.0010496863,0.95573044,0.029052854,0.0055289147,0.000096096395],"about_ca_topic_score_codex":0.00096551556,"about_ca_topic_score_gemma":0.000005046305,"teacher_disagreement_score":0.04143293,"about_ca_system_score_codex":0.000050757644,"about_ca_system_score_gemma":0.00015102803,"threshold_uncertainty_score":0.30047813},"labels":[],"label_agreement":null},{"id":"W2063232329","doi":"10.4161/auto.23908","title":"The emerging role of acetylation in the regulation of autophagy","year":2013,"lang":"en","type":"review","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":177,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Nautical Research Society","funders":"Indo-French Centre for the Promotion of Advanced Research; Aix-Marseille Université","keywords":"Autophagy; Biology; Cell biology; Acetylation; ATG16L1; Effector; BAG3; Ubiquitin; Organelle; Cytosol; Biochemistry; Apoptosis","score_opus":0.028359620657892794,"score_gpt":0.3444201360301086,"score_spread":0.31606051537221586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063232329","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021593177,0.9939962,0.000012345514,0.00008413459,0.00017442952,0.0015171155,0.000010247793,0.00002700099,0.0020192193],"genre_scores_gemma":[0.01606153,0.98257697,0.00006990502,0.000060704795,0.00020457353,0.0002004871,0.000094850635,0.00004635422,0.00068460696],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975621,0.0003468608,0.0010733646,0.00026572085,0.00048529753,0.00026664446],"domain_scores_gemma":[0.99756116,0.00050971605,0.00085088157,0.0008827509,0.0001492526,0.000046231373],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068717205,0.00030492686,0.0011532163,0.00020000222,0.00008949581,0.000017250846,0.00040302417,0.0002736811,0.00021504016],"category_scores_gemma":[0.0001411282,0.00016061621,0.0005078157,0.0005825817,0.0001483879,0.0000920652,0.00004993375,0.00034200822,0.000042375294],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017528957,0.000104876795,0.0000069597936,0.0022645376,0.00017379658,0.0000031896304,0.0004517478,0.0000045045003,0.00017493695,0.0051705847,0.00028190977,0.9913454],"study_design_scores_gemma":[0.0007058343,0.00016419384,0.0042083147,0.00456569,0.0008904808,0.000041886793,0.0002555946,0.000461826,0.0012368151,0.00300379,0.9842385,0.00022705847],"about_ca_topic_score_codex":0.0000701805,"about_ca_topic_score_gemma":0.000004335444,"teacher_disagreement_score":0.9911184,"about_ca_system_score_codex":0.00006946351,"about_ca_system_score_gemma":0.0003002291,"threshold_uncertainty_score":0.6549739},"labels":[],"label_agreement":null},{"id":"W2063430669","doi":"10.1016/j.mib.2014.11.020","title":"Emerging themes in bacterial autophagy","year":2014,"lang":"en","type":"review","venue":"Current Opinion in Microbiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Crohn's and Colitis Canada","keywords":"Biology; Autophagy; PI3K/AKT/mTOR pathway; Parkin; Cell biology; Optineurin; ATG8; Genetics; Signal transduction","score_opus":0.06718891358768983,"score_gpt":0.4161415277453574,"score_spread":0.34895261415766754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063430669","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00031401496,0.9874049,0.0000109927505,0.0000309119,0.011169587,0.00086895435,0.00006848309,0.000044289318,0.00008789787],"genre_scores_gemma":[0.00005302712,0.9955989,0.000027657235,0.000030308955,0.0015309087,0.00015246522,0.002502444,0.000051915635,0.000052358966],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99748826,0.00040268197,0.0009848692,0.00059952564,0.000049322985,0.00047533188],"domain_scores_gemma":[0.99901325,0.00013619532,0.00030834938,0.00043365345,0.000024747551,0.00008379488],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002680062,0.0004634105,0.0021852234,0.00059102365,0.000025428437,0.000010078778,0.00026325826,0.0004926713,0.00067507103],"category_scores_gemma":[0.00005839439,0.00036666566,0.0004249479,0.00030688717,0.00010862901,0.000029373126,0.000109046596,0.000707252,0.0002593998],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004899992,0.00027165492,0.000050860195,0.017962476,0.000074258656,0.000007080974,0.00008268551,2.2816565e-7,0.000078267105,0.00026650436,0.0027899982,0.978367],"study_design_scores_gemma":[0.0012717731,0.00008195158,0.000048125778,0.021537736,0.000073173884,0.00009588391,0.000004879447,0.0000025311126,0.000009118428,0.000054630364,0.9765263,0.0002938507],"about_ca_topic_score_codex":0.0000056914796,"about_ca_topic_score_gemma":0.0000015837068,"teacher_disagreement_score":0.9780731,"about_ca_system_score_codex":0.00017931208,"about_ca_system_score_gemma":0.0003466763,"threshold_uncertainty_score":0.9998785},"labels":[],"label_agreement":null},{"id":"W2064093478","doi":"10.1089/ars.2010.3554","title":"Autophagy Signaling Through Reactive Oxygen Species","year":2010,"lang":"en","type":"review","venue":"Antioxidants and Redox Signaling","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":228,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; Reactive oxygen species; Signal transduction; Biology; Programmed cell death; Mitochondrion; Cell signaling; Mitochondrial ROS; Lysosome; Biochemistry; Apoptosis; Enzyme","score_opus":0.047800614365676626,"score_gpt":0.3414694293484332,"score_spread":0.2936688149827566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064093478","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005518665,0.98847413,0.00014399893,0.00003861479,0.0005364476,0.0009577556,0.00007470953,0.00017131715,0.004084386],"genre_scores_gemma":[0.0023732511,0.99186945,0.0011006607,0.00025003462,0.0015130364,0.000047589507,0.00018959676,0.00015545363,0.0025009052],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99705696,0.00012695685,0.0009009051,0.0008665379,0.0004505885,0.0005980529],"domain_scores_gemma":[0.99820477,0.00025835863,0.0005672357,0.0005679689,0.00013190883,0.00026976957],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034704895,0.00076870446,0.0024624898,0.00023809868,0.00038988152,0.00012006131,0.0002295955,0.00080006284,0.00048643647],"category_scores_gemma":[0.000072909,0.0005555724,0.0008135018,0.0003581016,0.00027483574,0.00021650507,0.00010423307,0.0011925607,0.00007177027],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011783614,0.00042743495,0.000018103785,0.014637656,0.0023123587,0.001433597,0.0008287036,7.8266294e-7,0.021905864,0.0034501145,0.0004064581,0.9544611],"study_design_scores_gemma":[0.0007059747,0.00015176032,0.0000395522,0.017183026,0.002359081,0.0005033898,0.00013327503,0.000005920534,0.004381229,0.00072442065,0.97313917,0.000673196],"about_ca_topic_score_codex":0.00002655597,"about_ca_topic_score_gemma":7.5610427e-7,"teacher_disagreement_score":0.9727327,"about_ca_system_score_codex":0.00006007175,"about_ca_system_score_gemma":0.00041777946,"threshold_uncertainty_score":0.9996896},"labels":[],"label_agreement":null},{"id":"W2064127635","doi":"10.1038/embor.2012.14","title":"Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment","year":2012,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":702,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Ottawa; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"PINK1; Parkin; Mitophagy; Mitochondrion; Cell biology; Biology; Ubiquitin ligase; Ubiquitin; Autophagy; Biochemistry; Parkinson's disease; Medicine","score_opus":0.03639433169736897,"score_gpt":0.3221536096137595,"score_spread":0.28575927791639055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064127635","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9817741,0.012800468,0.000048225596,0.000271325,0.00040550463,0.0008675278,0.0000012765994,0.00016050019,0.003671099],"genre_scores_gemma":[0.9947321,0.00006912703,0.001227389,0.00041214543,0.0011893742,0.00016075755,0.00004216313,0.000036467514,0.002130475],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99835086,0.000025166933,0.00048253857,0.00036551192,0.0003537536,0.00042215257],"domain_scores_gemma":[0.99882096,0.000011266757,0.00033156772,0.00035059213,0.00008216959,0.00040341585],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028474655,0.00022416454,0.00033808852,0.00007632192,0.00015968872,0.000049378443,0.000034019664,0.00011946056,0.0001924993],"category_scores_gemma":[0.00006569612,0.0001778295,0.00008259205,0.00013110384,0.00009727627,0.0002873625,0.00003745959,0.00014570536,0.0000061416404],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00089510926,0.002302963,0.45190388,0.001427338,0.00041762405,0.0056788544,0.0068979515,0.0000023797443,0.06553907,0.00008088585,0.019792503,0.44506145],"study_design_scores_gemma":[0.0036514697,0.0005852225,0.4801121,0.0016652204,0.0010139933,0.013728358,0.0005422819,0.0002448643,0.101917736,0.0021020237,0.39326382,0.0011729196],"about_ca_topic_score_codex":0.000010525294,"about_ca_topic_score_gemma":9.679151e-7,"teacher_disagreement_score":0.44388852,"about_ca_system_score_codex":0.000062219486,"about_ca_system_score_gemma":0.00022834755,"threshold_uncertainty_score":0.7251677},"labels":[],"label_agreement":null},{"id":"W2064286012","doi":"10.1111/jop.12250","title":"Inhibition of autophagy augments apoptosis in human oral squamous cell carcinoma under nutrient depletion","year":2014,"lang":"en","type":"article","venue":"Journal of Oral Pathology and Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Natural Science Foundation of China","keywords":"Autophagy; Apoptosis; Programmed cell death; Flow cytometry; Transfection; Cell culture; Biology; MTT assay; Cell growth; Cell; Cell biology; Cancer research; Molecular biology; Biochemistry","score_opus":0.020590602412921155,"score_gpt":0.29831584220819984,"score_spread":0.2777252397952787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064286012","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963946,0.0010954931,0.0009010287,0.0009090724,0.0002287402,0.00013842834,0.0000014719087,0.000006087869,0.0003250776],"genre_scores_gemma":[0.99845827,0.00010673676,0.00018732899,0.0009822547,0.00017325855,0.0000024867518,0.000012642392,0.000011448591,0.00006560002],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987074,0.00015739979,0.00059841375,0.00013347124,0.00023166057,0.00017163646],"domain_scores_gemma":[0.9991762,0.000047990696,0.00037607914,0.00012168933,0.00012658075,0.00015144695],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000704409,0.00013035674,0.00055509584,0.00031638372,0.00004393532,0.0000018121159,0.000044308035,0.00014130479,0.00010795777],"category_scores_gemma":[0.000068195375,0.00009345157,0.000070592454,0.00013052011,0.00021947622,0.00007056719,0.000017288894,0.0002641837,0.0000012697041],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00217098,0.001786195,0.11107877,0.00039761988,0.00005608311,0.00096753886,0.0023306184,0.000027299997,0.873156,0.0022214588,0.0013114238,0.004495977],"study_design_scores_gemma":[0.029627413,0.010906036,0.7181023,0.00038926673,0.00049407384,0.0010260628,0.0009858937,0.000090931826,0.22892405,0.008944595,0.00033311005,0.00017629717],"about_ca_topic_score_codex":0.000036068006,"about_ca_topic_score_gemma":0.000004370718,"teacher_disagreement_score":0.644232,"about_ca_system_score_codex":0.00004651844,"about_ca_system_score_gemma":0.00004361417,"threshold_uncertainty_score":0.38108444},"labels":[],"label_agreement":null},{"id":"W2065126270","doi":"10.1038/sj.cdd.4402233","title":"Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells","year":2007,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":687,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; University of Manitoba","funders":"CancerCare Manitoba Foundation","keywords":"Autophagy; Programmed cell death; Cell biology; Apoptosis; Reactive oxygen species; Oxidative stress; Chemistry; Cancer cell; Biology; Biochemistry; Cancer","score_opus":0.015503240505513506,"score_gpt":0.26868486728336927,"score_spread":0.2531816267778558,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2065126270","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955194,0.0023238112,0.0006626767,0.000018506593,0.00008864263,0.0003782155,0.00003055722,0.000015785296,0.0009624172],"genre_scores_gemma":[0.9971316,0.0024272455,0.000082341925,0.00006498773,0.000038931517,0.000016345943,0.000054449312,0.00001319655,0.00017088992],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905163,0.000029362158,0.0002789976,0.00023281702,0.00019336224,0.00021380643],"domain_scores_gemma":[0.9995346,0.000058134563,0.00011210182,0.00010078807,0.000044501714,0.00014988249],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011189267,0.00015882739,0.00026541582,0.00017784793,0.00004160266,0.000013625219,0.000039617767,0.00012894745,0.00009421533],"category_scores_gemma":[0.0000037035477,0.00013265412,0.0000449242,0.00010151981,0.000030142697,0.00009498284,0.000013295263,0.00012811054,0.0000010867822],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044559795,0.0007172338,0.20571095,0.0005072976,0.00005515579,0.000008974754,0.002851518,0.0000049618475,0.77928215,0.00012444479,0.000005810895,0.010285883],"study_design_scores_gemma":[0.0018042255,0.0000982972,0.41260487,0.000055364206,0.00007891734,3.6994675e-7,0.00023325582,0.00011009472,0.58479416,0.0001401738,0.0000053102744,0.000074951815],"about_ca_topic_score_codex":0.00021298652,"about_ca_topic_score_gemma":0.00004136146,"teacher_disagreement_score":0.2068939,"about_ca_system_score_codex":0.000042563108,"about_ca_system_score_gemma":0.000049407055,"threshold_uncertainty_score":0.5409478},"labels":[],"label_agreement":null},{"id":"W2065189879","doi":"10.1007/s00246-011-9893-z","title":"Epigenetic Regulation of E2F-1-Dependent Bnip3 Transcription and Cell Death by Nuclear Factor-κB and Histone Deacetylase-1","year":2011,"lang":"en","type":"article","venue":"Pediatric Cardiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Manitoba Health Research Council","keywords":"Histone deacetylase; Transcription factor; Cell biology; Epigenetics; E2F; Histone deacetylase 5; Histone; HDAC4; Biology; HDAC1; Programmed cell death; Cancer research; Apoptosis; Genetics; Gene","score_opus":0.018407705797273893,"score_gpt":0.23619780385346248,"score_spread":0.2177900980561886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2065189879","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9856076,0.012306262,0.00053010107,0.000024501494,0.0001208265,0.00023036402,0.00003644974,0.00003173191,0.0011121234],"genre_scores_gemma":[0.992642,0.0067214603,0.00018950232,0.000054438067,0.0001706627,0.0000068714367,0.000022506927,0.000020454725,0.00017214267],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991918,0.000070991606,0.00022302956,0.00024511875,0.000107290754,0.00016176343],"domain_scores_gemma":[0.9995497,0.000028821527,0.000087970475,0.00017086814,0.00004119377,0.000121433695],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009018225,0.00012640597,0.0003469162,0.00009315366,0.000040276347,0.0000023273867,0.000036403268,0.00015560784,0.00012989697],"category_scores_gemma":[0.000010002179,0.00011724821,0.00007644286,0.000057740126,0.000072786104,0.00003678184,0.000015350655,0.00009371734,0.0000067651004],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017675967,0.00047721184,0.38761064,0.00062481535,0.00045824732,0.00009582401,0.0048777196,0.0000091786205,0.5899074,0.00050362415,0.002326146,0.011341576],"study_design_scores_gemma":[0.0024631983,0.0006817421,0.975793,0.0000046358796,0.0007904619,0.000098596334,0.00009185029,0.000044618668,0.018822946,0.0004248383,0.000603829,0.00018025986],"about_ca_topic_score_codex":0.00008508499,"about_ca_topic_score_gemma":0.0000010176662,"teacher_disagreement_score":0.5881824,"about_ca_system_score_codex":0.000029290963,"about_ca_system_score_gemma":0.00002820252,"threshold_uncertainty_score":0.47812432},"labels":[],"label_agreement":null},{"id":"W2065502699","doi":"10.1007/s00425-010-1304-9","title":"Environmentally induced programmed cell death in leaf protoplasts of Aponogeton madagascariensis","year":2010,"lang":"en","type":"article","venue":"Planta","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"University of Toronto; Dalhousie University","keywords":"Programmed cell death; Protoplast; Vacuole; Biology; Cell biology; Chloroplast; Mitochondrion; Mitochondrial permeability transition pore; Plant cell; Terminal deoxynucleotidyl transferase; Apoptosis; Cytoplasm; Biophysics; TUNEL assay; Botany; Biochemistry","score_opus":0.013173443283417718,"score_gpt":0.25080113589774916,"score_spread":0.23762769261433145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2065502699","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958547,0.00003558518,0.0000034103937,0.000067804394,0.00008328532,0.0010068285,0.000016570752,0.000026349224,0.0029054703],"genre_scores_gemma":[0.99889094,0.000021701171,0.0004949511,0.00013006304,0.000049653245,0.000104514314,0.00006523676,0.000017919336,0.00022504662],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991564,0.000018523164,0.00021725589,0.00019825938,0.00019522868,0.00021429181],"domain_scores_gemma":[0.9995035,0.000030410065,0.000076275384,0.00026646064,0.000009562787,0.000113819944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000103582366,0.00012259898,0.00023172423,0.00008738501,0.000019025018,0.0000055328005,0.00008487628,0.00011505412,0.00021029613],"category_scores_gemma":[0.0000144353535,0.00010523859,0.000057490714,0.000075358796,0.000040443,0.000041440984,0.00002855729,0.00024790133,0.000033185166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054842635,0.00082125835,0.25515512,0.00009204818,0.0000329274,0.00014100909,0.00040531877,4.6620983e-7,0.7385616,0.000065270535,0.00005689923,0.0041197315],"study_design_scores_gemma":[0.0022091668,0.00028509737,0.31200862,0.00004343492,0.00003736092,0.00004937615,0.000061620274,0.00006356331,0.6835399,0.00006194809,0.001529284,0.00011058912],"about_ca_topic_score_codex":0.00008891219,"about_ca_topic_score_gemma":0.000046242778,"teacher_disagreement_score":0.056853503,"about_ca_system_score_codex":0.000021456317,"about_ca_system_score_gemma":0.00006720701,"threshold_uncertainty_score":0.42915052},"labels":[],"label_agreement":null},{"id":"W2065609114","doi":"10.1074/jbc.m111.310599","title":"TLR2 and RIP2 Pathways Mediate Autophagy of Listeria monocytogenes via Extracellular Signal-regulated Kinase (ERK) Activation","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; Takeda Oncology; University of Alberta; St. Jude Children's Research Hospital; Yale University","keywords":"Autophagy; TLR2; Cell biology; MAPK/ERK pathway; Innate immune system; Signal transduction; Biology; Listeria monocytogenes; Inflammasome; Microbiology; Immune system; Receptor; TLR4; Immunology; Biochemistry; Apoptosis; Bacteria","score_opus":0.06235183285933555,"score_gpt":0.2596958039972013,"score_spread":0.19734397113786578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2065609114","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996181,0.0030317097,0.00034579984,0.000039617255,0.000044977245,0.000080190366,0.000007951643,0.000017641576,0.00025112266],"genre_scores_gemma":[0.99864626,0.00041102775,0.0005896196,0.00006290073,0.00019877648,0.0000022290753,0.0000145985105,0.000010480026,0.000064087864],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989342,0.00004085509,0.00053698657,0.00015579101,0.00017229495,0.00015984174],"domain_scores_gemma":[0.9988982,0.000054767504,0.00051748054,0.00014753421,0.00016414646,0.00021788843],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00023104108,0.00016379367,0.00043040523,0.00003561035,0.000032189226,0.0000057768025,0.00011110226,0.00025913864,0.0009947722],"category_scores_gemma":[0.00007534026,0.000108094646,0.00016152079,0.000086003616,0.00016481953,0.0000638827,0.000033909753,0.00019620685,0.0000016431302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011933121,0.00033899612,0.00224691,0.00008849568,0.00013461673,0.0002131929,0.00013095044,9.788167e-7,0.99095976,0.000013763196,0.000019058947,0.004659983],"study_design_scores_gemma":[0.0013069346,0.0004907419,0.048166424,0.00010217908,0.00007953529,0.00019786479,0.00006676432,0.000074590745,0.9483225,0.0009937827,0.00009486366,0.00010385011],"about_ca_topic_score_codex":0.0000038650187,"about_ca_topic_score_gemma":3.286228e-8,"teacher_disagreement_score":0.04591951,"about_ca_system_score_codex":0.000029443603,"about_ca_system_score_gemma":0.00006199159,"threshold_uncertainty_score":0.99991846},"labels":[],"label_agreement":null},{"id":"W2067020827","doi":"10.1038/cddis.2012.61","title":"Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts","year":2012,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":123,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Canadian Institutes of Health Research; Manitoba Health Research Council; Natural Sciences and Engineering Research Council of Canada; GlaxoSmithKline","keywords":"Autophagy; Unfolded protein response; Cell biology; Programmed cell death; Apoptosis; Endoplasmic reticulum; Chemistry; Simvastatin; Protein kinase A; Biology; Kinase; Pharmacology; Biochemistry","score_opus":0.018739141129871063,"score_gpt":0.27885408769905295,"score_spread":0.2601149465691819,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067020827","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99065375,0.0072852946,0.000006165709,0.000048663136,0.000093703995,0.00044111532,0.00009687072,0.00003715464,0.0013372579],"genre_scores_gemma":[0.9986143,0.00031023173,0.000053686028,0.00024421062,0.00029123458,0.000019041761,0.00011421154,0.0000292486,0.00032383378],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987016,0.00006711874,0.00031745769,0.00029802942,0.00022582956,0.00038998105],"domain_scores_gemma":[0.9984702,0.000053276948,0.000102812926,0.00025338455,0.00003878222,0.0010815792],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118353426,0.00023578755,0.000344536,0.00014859419,0.000088249675,0.00001746178,0.00004771048,0.000115041694,0.00014946006],"category_scores_gemma":[0.000029496385,0.00020825594,0.00013145505,0.00009289829,0.000059591912,0.00020463149,0.00005520196,0.00014304544,0.000008762931],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035034472,0.0033064508,0.6110281,0.002734403,0.00014462249,0.0002984208,0.0015570046,0.000015517719,0.37154296,0.0041144183,0.0004241247,0.0013305522],"study_design_scores_gemma":[0.01034197,0.00037311603,0.5046615,0.0002717672,0.00051952654,0.0000060960274,0.00013131503,0.00014328532,0.48145318,0.0015986717,0.000112868496,0.00038670484],"about_ca_topic_score_codex":0.00010428256,"about_ca_topic_score_gemma":0.0000019745412,"teacher_disagreement_score":0.10991021,"about_ca_system_score_codex":0.000030744093,"about_ca_system_score_gemma":0.00011937332,"threshold_uncertainty_score":0.84924304},"labels":[],"label_agreement":null},{"id":"W2067465643","doi":"10.4161/auto.5.8.10167","title":"Hypoxia-induced downregulation of autophagy mediator Beclin-1 reduces the susceptibility of malignant intestinal epithelial cells to hypoxia-dependent apoptosis","year":2009,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"IWK Health Centre; Chinese Academy of Agricultural Sciences; Dalhousie University","keywords":"Downregulation and upregulation; Apoptosis; Biology; Cell biology; Hypoxia (environmental); Caspase; Autophagy; Programmed cell death; Cancer cell; Caspase 8; Cancer research; Chemistry; Cancer; Biochemistry","score_opus":0.02008803972244075,"score_gpt":0.2859938997190153,"score_spread":0.2659058599965745,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067465643","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958983,0.0003241314,0.000252802,0.0012047347,0.00048025063,0.001170994,0.00007655443,0.0001206815,0.000471555],"genre_scores_gemma":[0.99715966,0.00005402923,0.0011653578,0.0006957712,0.00043690082,0.000038973074,0.000027224549,0.000038272658,0.000383788],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965076,0.00022659796,0.0011771959,0.0006426256,0.00091864,0.0005273759],"domain_scores_gemma":[0.99729645,0.00033749323,0.00053457037,0.0010768153,0.0004027145,0.0003519629],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00087659585,0.0004094897,0.00085379824,0.00024041196,0.0001252785,0.000021088841,0.00049071625,0.00021947912,0.00049912557],"category_scores_gemma":[0.00034752022,0.00029134774,0.000399451,0.00053230755,0.00020022126,0.00013862432,0.000091136004,0.00028592645,0.00006991421],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007538815,0.0008153272,0.00013531734,0.00006232815,0.0001243519,0.00001797087,0.00090207276,0.00006132166,0.9684559,0.00080830365,0.00024307368,0.027620157],"study_design_scores_gemma":[0.0013734794,0.0015068863,0.1545435,0.00011107662,0.00021952817,0.000019325904,0.00018834673,0.00020695273,0.8400334,0.0014975573,0.000081475366,0.00021844388],"about_ca_topic_score_codex":0.00013088902,"about_ca_topic_score_gemma":0.0000090474505,"teacher_disagreement_score":0.15440819,"about_ca_system_score_codex":0.00012922117,"about_ca_system_score_gemma":0.0003931168,"threshold_uncertainty_score":0.99995387},"labels":[],"label_agreement":null},{"id":"W2068689727","doi":"10.1371/journal.pone.0114964","title":"Induction of Covalently Crosslinked p62 Oligomers with Reduced Binding to Polyubiquitinated Proteins by the Autophagy Inhibitor Verteporfin","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Cancer Society Research Institute; University of British Columbia","keywords":"Verteporfin; Autophagy; Cell biology; Singlet oxygen; Chemistry; Autophagosome; Cytoplasm; Signal transducing adaptor protein; Biophysics; Biochemistry; Biology; Signal transduction; Oxygen; Apoptosis","score_opus":0.027273963421465645,"score_gpt":0.24848143304953937,"score_spread":0.22120746962807372,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068689727","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99627274,0.00009516953,0.00008710767,0.0015888979,0.000051172126,0.0012170022,0.000021423259,0.000110569585,0.00055590825],"genre_scores_gemma":[0.9973493,0.000009863071,0.0004280758,0.00057044916,0.00018081462,0.00012656531,0.000049058744,0.00004467632,0.0012411561],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985214,0.00007947904,0.00030842816,0.00027861298,0.00052650383,0.00028559953],"domain_scores_gemma":[0.9990678,0.0000405399,0.0001744994,0.00036073598,0.00016996676,0.00018649944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002450858,0.00017888001,0.00036473587,0.00012373307,0.00013008287,0.000015973086,0.000114819915,0.00010461322,0.00010167744],"category_scores_gemma":[0.00013374058,0.00012208143,0.00005590458,0.0004399541,0.00013579665,0.00008077934,0.000028278817,0.00021822851,0.00004205723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00078151334,0.0012555271,0.00065053283,0.00013505919,0.00039040588,0.0000051689835,0.00043458084,0.0000015123712,0.99486065,0.00010310331,0.00027360127,0.0011083368],"study_design_scores_gemma":[0.0021587664,0.0013168049,0.007513688,0.0005552901,0.0002499034,0.000009277885,0.00012212613,0.00009921822,0.9875954,0.000027556403,0.00020462311,0.00014734596],"about_ca_topic_score_codex":0.00007743297,"about_ca_topic_score_gemma":0.0000028068148,"teacher_disagreement_score":0.007265258,"about_ca_system_score_codex":0.00007580094,"about_ca_system_score_gemma":0.000119090895,"threshold_uncertainty_score":0.49783364},"labels":[],"label_agreement":null},{"id":"W2068978379","doi":"10.4161/auto.26452","title":"Placental autophagy regulation by the BOK-MCL1 rheostat","year":2013,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Canadian Institutes of Health Research; U.S. Public Health Service; Canada Research Chairs","keywords":"Autophagy; Cell biology; Biology; MCL1; BECN1; Programmed cell death; Downregulation and upregulation; HEK 293 cells; Cell culture; Apoptosis; Biochemistry; Genetics","score_opus":0.005528334336107247,"score_gpt":0.2354257294572592,"score_spread":0.22989739512115195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068978379","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98067105,0.003216169,0.00029934393,0.003016288,0.0004711575,0.0010625618,0.000024417937,0.00032857974,0.01091041],"genre_scores_gemma":[0.97050077,0.00010203958,0.00018112765,0.0043788506,0.00029539384,0.00014398652,0.00016122509,0.00005581841,0.024180762],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.99821717,0.00009044635,0.00037046452,0.0003870332,0.000455161,0.0004797029],"domain_scores_gemma":[0.99873817,0.000117198884,0.00013001973,0.0006659394,0.000099199824,0.00024945024],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00016205305,0.00027830095,0.0003099719,0.00007066096,0.0002481949,0.00007745429,0.00022388055,0.00015840032,0.007216255],"category_scores_gemma":[0.000046954756,0.00018910039,0.00018563577,0.00023715124,0.00018791184,0.0002772573,0.00006125028,0.00026419258,0.002189797],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046220058,0.0011183703,0.0032192038,0.00011450695,0.0006480692,0.00012548584,0.0016129012,0.00003244975,0.21482557,0.012205615,0.63302374,0.13261189],"study_design_scores_gemma":[0.0070779356,0.00074139633,0.4662691,0.00011462935,0.00029097273,0.00040796754,0.0005121549,0.007863158,0.3551628,0.008030027,0.15275711,0.00077272527],"about_ca_topic_score_codex":0.0002121598,"about_ca_topic_score_gemma":0.0000024554238,"teacher_disagreement_score":0.48026663,"about_ca_system_score_codex":0.00011325843,"about_ca_system_score_gemma":0.00010760957,"threshold_uncertainty_score":0.99858713},"labels":[],"label_agreement":null},{"id":"W2069237892","doi":"10.3892/ijo.2014.2264","title":"Suppression of autophagic genes sensitizes CUG2-overexpressing A549 human lung cancer cells to oncolytic vesicular stomatitis virus-induced apoptosis","year":2014,"lang":"en","type":"article","venue":"International Journal of Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Oncolytic virus; Autophagy; Vesicular stomatitis virus; Biology; ATG5; A549 cell; Apoptosis; Oncogene; Cell biology; Cancer research; Virology; Virus; Cell cycle","score_opus":0.017188956493791895,"score_gpt":0.37089663954915947,"score_spread":0.3537076830553676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069237892","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994416,0.0004335021,0.0008661715,0.0013662052,0.0017593272,0.0001681168,0.000019487155,0.000015715344,0.0009554655],"genre_scores_gemma":[0.99559206,0.00016993254,0.0015228109,0.0014076589,0.001152817,0.000007860645,0.000006285537,0.000025250527,0.000115307186],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981622,0.00016902864,0.0006905545,0.00017199728,0.0006154892,0.00019074546],"domain_scores_gemma":[0.99809325,0.00018242109,0.0006676092,0.00016583914,0.0006805894,0.00021026391],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031871308,0.00016336874,0.00055221526,0.00032931048,0.0000612496,0.000022087008,0.00027878326,0.00014043233,0.00054213655],"category_scores_gemma":[0.00008255216,0.0001366774,0.0002263643,0.00008979726,0.0000627246,0.00014386278,0.000072907234,0.00021997487,0.000009279357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004551069,0.00035278182,0.00090129464,0.000037918926,0.00054019754,0.00016621758,0.00048209517,0.0003757805,0.96837723,0.00013812112,0.0025610847,0.02561217],"study_design_scores_gemma":[0.0030053847,0.0010934313,0.01134937,0.00069191295,0.00024393297,0.0001845147,0.000068908776,0.001072277,0.9763361,0.00021565674,0.005607297,0.00013118752],"about_ca_topic_score_codex":0.00012232493,"about_ca_topic_score_gemma":0.000010810996,"teacher_disagreement_score":0.025480982,"about_ca_system_score_codex":0.00041760984,"about_ca_system_score_gemma":0.0003403463,"threshold_uncertainty_score":0.59360147},"labels":[],"label_agreement":null},{"id":"W2069952533","doi":"10.1074/jbc.m513377200","title":"Autophagy Contributes to Caspase-independent Macrophage Cell Death","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":220,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Autophagy; Cell biology; Programmed cell death; TRIF; Poly ADP ribose polymerase; Small interfering RNA; ATG5; Caspase 1; Biology; Caspase; Chemistry; Apoptosis; Innate immune system; Cell culture; Receptor; Toll-like receptor; Biochemistry; Transfection; Polymerase","score_opus":0.014740621513676944,"score_gpt":0.26694228628027683,"score_spread":0.2522016647665999,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069952533","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907787,0.0032715448,0.00040172503,0.00045060556,0.000099699384,0.00010374943,0.000017251128,0.000026285663,0.004850473],"genre_scores_gemma":[0.9962613,0.00008566996,0.00051613303,0.00087332574,0.00063346897,0.0000035620544,0.000012871381,0.000010745313,0.0016029524],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988096,0.000024361523,0.0004864744,0.0001724135,0.00023354507,0.00027365203],"domain_scores_gemma":[0.9990889,0.00007335284,0.00021633867,0.00016637672,0.00017359293,0.00028146338],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021063286,0.0001693097,0.00042817192,0.000035853995,0.000048020243,0.00001974146,0.00016738416,0.00022289975,0.0007502489],"category_scores_gemma":[0.000086762964,0.0001091275,0.000268276,0.00010917218,0.00004828485,0.000025769134,0.000040303712,0.00032604334,0.000033898403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000589837,0.0005618967,0.009731542,0.00003983096,0.00006656721,0.002106915,0.0000066452358,0.000016943244,0.98376733,0.000041795854,0.0026402446,0.00043046547],"study_design_scores_gemma":[0.002004422,0.00032979206,0.067272685,0.000049768372,0.00006681318,0.00047626597,0.000028692244,0.000010215315,0.92325985,0.0007983467,0.0055887573,0.00011436766],"about_ca_topic_score_codex":0.000007300653,"about_ca_topic_score_gemma":1.3397326e-7,"teacher_disagreement_score":0.06050744,"about_ca_system_score_codex":0.000120870194,"about_ca_system_score_gemma":0.00010425489,"threshold_uncertainty_score":0.8214699},"labels":[],"label_agreement":null},{"id":"W2070536046","doi":"10.1038/nm.3097","title":"Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy","year":2013,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":235,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Parkinson's UK; National Institute for Health and Care Research","keywords":"Neuroprotection; Autophagy; TSC1; Ischemia; Neuroscience; mTORC1; Downregulation and upregulation; Hippocampal formation; Biology; Pharmacology; Medicine; Cell biology; PI3K/AKT/mTOR pathway; Signal transduction; Internal medicine; Gene; Apoptosis","score_opus":0.0043773910904491165,"score_gpt":0.25712434765965775,"score_spread":0.25274695656920865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070536046","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96479774,0.004937545,0.0001567373,0.009901397,0.0008012276,0.0008501261,0.000004515958,0.00029372473,0.018257007],"genre_scores_gemma":[0.9747734,0.0002039131,0.00011281551,0.019359939,0.0011487405,0.00007960107,0.00012944585,0.000052315703,0.0041397996],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981813,0.00005249359,0.00037484427,0.00044515205,0.0005454319,0.00040080532],"domain_scores_gemma":[0.9987139,0.00006941754,0.00014657709,0.00047012948,0.00022171969,0.00037821836],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00021619709,0.00029450044,0.00045530958,0.0001579447,0.000120795434,0.000017539573,0.00013759876,0.00049762224,0.0026937858],"category_scores_gemma":[0.00038816073,0.00021305076,0.000097546676,0.00037141758,0.000179859,0.00015781728,0.000029872235,0.00145555,0.0001834396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010969452,0.000110975845,0.0005734575,0.00007243377,0.00011136483,0.00007518065,0.00024603578,0.0000010923666,0.7987989,0.00009499099,0.1681912,0.03161463],"study_design_scores_gemma":[0.008109603,0.0010406415,0.01867147,0.0006081917,0.00024055067,0.00014741991,0.00039345052,0.00089746545,0.7956809,0.00042161928,0.17330131,0.00048737126],"about_ca_topic_score_codex":0.00010518527,"about_ca_topic_score_gemma":9.989574e-7,"teacher_disagreement_score":0.03112726,"about_ca_system_score_codex":0.000086631524,"about_ca_system_score_gemma":0.00009208783,"threshold_uncertainty_score":0.9982179},"labels":[],"label_agreement":null},{"id":"W2071221374","doi":"10.1038/nrm1660","title":"Autophagy in metazoans: cell survival in the land of plenty","year":2005,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":750,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Autophagy; Extracellular; Cell biology; Nutrient; Biology; Cytoplasm; Intracellular; Signal transduction; Essential nutrient; Cell; Catabolism; Biochemistry; Ecology; Metabolism; Apoptosis","score_opus":0.029990838224629442,"score_gpt":0.3694382933148463,"score_spread":0.33944745509021684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071221374","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00017345925,0.9898712,0.000012361399,0.00004652414,0.00023921001,0.0027197124,0.000051473966,0.000012885102,0.0068731904],"genre_scores_gemma":[0.000702171,0.9970789,0.00022679535,0.0009003123,0.00017364872,0.00022258263,0.0005288405,0.00005380937,0.00011295602],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9950309,0.0022051046,0.0014229607,0.0006543579,0.00022624215,0.00046046893],"domain_scores_gemma":[0.99786675,0.00027976566,0.00068478583,0.0010391773,0.000042401534,0.00008711412],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0015490805,0.00063288416,0.004098989,0.0003871059,0.000017918694,0.000006538841,0.00065235177,0.0015902393,0.00017560375],"category_scores_gemma":[0.00013180438,0.0003505738,0.0012836675,0.0008343249,0.00010724297,0.000020933547,0.00007342729,0.0021867624,0.00007549637],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029234678,0.0005951379,0.00005826456,0.020238703,0.000119869415,0.0003738619,0.000049221686,5.396139e-7,0.00012503841,0.00030009623,0.00020054735,0.9779095],"study_design_scores_gemma":[0.0008518058,0.00013854046,0.000030888994,0.003825136,0.00092236546,0.000026687374,0.000004018142,0.0000014276714,0.00013558423,0.00005619385,0.99373657,0.0002707999],"about_ca_topic_score_codex":0.000019823436,"about_ca_topic_score_gemma":0.000018824187,"teacher_disagreement_score":0.993536,"about_ca_system_score_codex":0.000091667884,"about_ca_system_score_gemma":0.0003320848,"threshold_uncertainty_score":0.9998946},"labels":[],"label_agreement":null},{"id":"W2071633522","doi":"10.4161/cc.27302","title":"Another face of cell death","year":2013,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Biology; Peroxisome; Programmed cell death; Yeast; Cell biology; Cell; Face (sociological concept); Apoptosis; Biochemistry; Gene","score_opus":0.014194828245647958,"score_gpt":0.24248836939970053,"score_spread":0.22829354115405256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071633522","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.44271266,0.007944677,0.0003004854,0.110294305,0.00083329494,0.0016809665,0.000131399,0.00022502676,0.4358772],"genre_scores_gemma":[0.1498967,0.00030292434,0.0004612954,0.64578545,0.002160597,0.0000405472,0.00023914386,0.00016582798,0.20094752],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989748,0.000029823064,0.00021685193,0.00026322983,0.0002506554,0.00026461124],"domain_scores_gemma":[0.99911755,0.000038426308,0.000149526,0.0005858559,0.000049718732,0.00005889191],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00003249486,0.00022694547,0.00040810462,0.00007173788,0.000021720894,0.000008476408,0.00016286489,0.00047428856,0.004796257],"category_scores_gemma":[0.0000028443178,0.00018659547,0.00020624911,0.00005516092,0.000050545004,0.000028162847,0.000027871994,0.0005490517,0.0012663231],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016111664,0.00012397814,0.00014288122,0.00050402194,0.000051376293,0.00017223944,0.00012182603,0.0000013290244,0.013963826,0.0000019718339,0.9846555,0.00024494075],"study_design_scores_gemma":[0.0009961018,0.00012606349,0.00066844595,0.000085846565,0.00017141069,0.000004654574,0.000017521537,0.000036042373,0.17115583,0.00018586735,0.82633674,0.00021546303],"about_ca_topic_score_codex":0.000059459766,"about_ca_topic_score_gemma":1.1713765e-7,"teacher_disagreement_score":0.5354911,"about_ca_system_score_codex":0.000028311712,"about_ca_system_score_gemma":0.00008037618,"threshold_uncertainty_score":0.9995113},"labels":[],"label_agreement":null},{"id":"W2072182899","doi":"10.1155/2012/872091","title":"Implications of Therapy-Induced Selective Autophagy on Tumor Metabolism and Survival","year":2012,"lang":"en","type":"article","venue":"International Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria; BC Cancer Agency","funders":"Canadian Institutes of Health Research; Ovarian Cancer Canada","keywords":"Autophagy; Mitophagy; Reprogramming; Cell biology; Cancer research; Mitochondrion; Cancer; Cancer cell; Programmed cell death; Biology; Medicine; Apoptosis; Bioinformatics; Cell; Biochemistry; Internal medicine","score_opus":0.025650280301891756,"score_gpt":0.33529344040222764,"score_spread":0.3096431601003359,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072182899","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929976,0.0014079757,0.00009674125,0.0005309124,0.00071338366,0.00007611719,0.000014139014,0.000005177212,0.004157986],"genre_scores_gemma":[0.9980318,0.00042726728,0.00018642216,0.00071154727,0.00058371504,0.0000028635736,0.000004860535,0.000008267969,0.000043290336],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932396,0.00006867077,0.00028879914,0.00007181906,0.00013104835,0.00011572047],"domain_scores_gemma":[0.9990133,0.00013394964,0.00030831443,0.00007691149,0.0003664508,0.000101068],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020477799,0.00008337685,0.0002383501,0.00016500277,0.000017239125,0.000003660596,0.00012253449,0.000051943305,0.00012237366],"category_scores_gemma":[0.000044920973,0.000059282796,0.00010173593,0.000053844095,0.00005472465,0.00006333364,0.000015846621,0.0001428069,0.0000050405074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010063606,0.000670187,0.01797226,0.0000037780171,0.00047895382,0.000008872475,0.000330956,0.000001177822,0.95484537,0.010079495,0.00008348923,0.014519096],"study_design_scores_gemma":[0.0019264903,0.00046635553,0.4479766,0.000011828239,0.000042029602,0.00012459994,0.000039184622,0.0000039436754,0.5444072,0.0024540143,0.002495291,0.000052495187],"about_ca_topic_score_codex":0.000006828101,"about_ca_topic_score_gemma":2.6267818e-7,"teacher_disagreement_score":0.43000433,"about_ca_system_score_codex":0.000026987409,"about_ca_system_score_gemma":0.00008968195,"threshold_uncertainty_score":0.24174823},"labels":[],"label_agreement":null},{"id":"W2072522514","doi":"10.1074/jbc.m109.096628","title":"The PEA-15 Protein Regulates Autophagy via Activation of JNK","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pediatric Oncology Group","funders":"Deutsche Krebshilfe","keywords":"Autophagy; Phosphoprotein; Phosphorylation; Kinase; Cell biology; Protein kinase A; MAPK/ERK pathway; Biology; Programmed cell death; p38 mitogen-activated protein kinases; Serine; Apoptosis; Chemistry; Biochemistry","score_opus":0.013247691861525333,"score_gpt":0.26765031968312614,"score_spread":0.2544026278216008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072522514","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980159,0.00031941975,0.000049446277,0.0008037113,0.000058060006,0.00008288657,0.0000012734093,0.000009943878,0.0006593952],"genre_scores_gemma":[0.99871397,0.000047136313,0.0003142824,0.00007366635,0.00047461237,0.000002892006,0.0000030699912,0.000005103029,0.0003652796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992638,0.000019102516,0.00034818277,0.00007799829,0.0001736018,0.0001173102],"domain_scores_gemma":[0.9990859,0.0000957137,0.00037807997,0.00016418415,0.00017648899,0.00009962725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000284937,0.000086738546,0.00021091661,0.000011228783,0.000053153246,0.000007666042,0.0001459468,0.00017504705,0.00036663286],"category_scores_gemma":[0.00034757453,0.000042073134,0.00016016998,0.00006583974,0.00017885304,0.00003275646,0.000019821558,0.0004107558,0.000002065153],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043411105,0.00013074171,0.00055051676,0.000024174806,0.000058736627,0.000015841304,0.000015150554,4.5411042e-7,0.99341536,0.00003458643,0.00012696395,0.0051933513],"study_design_scores_gemma":[0.00057601894,0.00020385341,0.018170753,0.00004900635,0.000018153749,0.00012818543,0.000030554307,0.000021314543,0.97656786,0.0020933193,0.002094967,0.000046014058],"about_ca_topic_score_codex":8.3757925e-7,"about_ca_topic_score_gemma":5.1471954e-8,"teacher_disagreement_score":0.017620238,"about_ca_system_score_codex":0.00001534138,"about_ca_system_score_gemma":0.000073811345,"threshold_uncertainty_score":0.40143728},"labels":[],"label_agreement":null},{"id":"W2073115974","doi":"10.4161/15384101.2014.965003","title":"Mechanism of liponecrosis, a distinct mode of programmed cell death","year":2014,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Concordia University","keywords":"Biology; Cell biology; Proteostasis; Mitochondrion; Mitophagy; Phosphatidylethanolamine; Biochemistry; Cytosol; Programmed cell death; Phospholipid; Autophagy; Membrane; Phosphatidylcholine; Apoptosis","score_opus":0.009274956971142886,"score_gpt":0.25546365969293466,"score_spread":0.24618870272179177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073115974","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9830486,0.0002392614,0.002962593,0.00003182338,0.00006138048,0.00028353502,0.00001175818,0.0000425358,0.013318498],"genre_scores_gemma":[0.9977525,0.00003324631,0.0013844208,0.000085628824,0.00005146211,0.000020169191,0.00002308427,0.000024263529,0.0006252645],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919754,0.000030556886,0.00023187461,0.00016534151,0.00018822587,0.00018643195],"domain_scores_gemma":[0.99928004,0.000039787188,0.00012939348,0.00035759763,0.00006369477,0.00012947887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000095724834,0.000112297384,0.0002928983,0.0000435765,0.000025833771,0.0000035152025,0.000099299345,0.00006998356,0.00013473965],"category_scores_gemma":[0.000017801423,0.00009401052,0.00012992095,0.00008416878,0.00004935135,0.000023238561,0.000028194703,0.000072190654,0.000022087203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006011048,0.0033751961,0.00791124,0.0013662588,0.00010231936,0.000018034316,0.0011341203,0.000028741199,0.9676708,0.0071476516,0.00033060866,0.010313899],"study_design_scores_gemma":[0.0020062039,0.0004898384,0.0053985366,0.00005940247,0.00012887946,0.0000018646106,0.00004439266,0.0035568401,0.9826079,0.004824612,0.00077721215,0.0001043346],"about_ca_topic_score_codex":0.00010741141,"about_ca_topic_score_gemma":0.0000027755032,"teacher_disagreement_score":0.014937057,"about_ca_system_score_codex":0.000013106502,"about_ca_system_score_gemma":0.00004668,"threshold_uncertainty_score":0.38336378},"labels":[],"label_agreement":null},{"id":"W2073691055","doi":"10.4161/auto.26864","title":"Characterization of early autophagy signaling by quantitative phosphoproteomics","year":2013,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Phosphoproteomics; Autophagy; Phosphorylation; Biology; Cell biology; PI3K/AKT/mTOR pathway; Protein phosphorylation; Signal transduction; Mechanistic target of rapamycin; Quantitative proteomics; Autophagy-related protein 13; BAG3; TOR signaling; Proteomics; Biochemistry; Protein kinase A; Apoptosis","score_opus":0.011670329182442157,"score_gpt":0.25820797501712667,"score_spread":0.24653764583468452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073691055","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99698675,0.00050446676,0.00094388006,0.00014203941,0.00011794696,0.00076368445,0.00002527537,0.00007098259,0.0004449677],"genre_scores_gemma":[0.9971762,0.00008662996,0.0010335349,0.00045664716,0.000038527145,0.00010501027,0.000099900084,0.000036986075,0.00096661283],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986987,0.000047637644,0.00045976523,0.00027329862,0.00023812016,0.00028244918],"domain_scores_gemma":[0.9992283,0.00005406215,0.00019601203,0.00026545167,0.0001363217,0.00011983544],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000118516116,0.00018321506,0.00040265408,0.00013634941,0.00003528606,0.00001959496,0.00011238259,0.0001292658,0.0011603013],"category_scores_gemma":[0.00003920721,0.00017155931,0.000105272746,0.00030633144,0.000085361426,0.00027051673,0.000023682365,0.00015964848,0.00018355697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014038135,0.00026790224,0.0027632096,0.000051942967,0.000063866086,0.000018562356,0.00068784505,0.0000033629622,0.99124706,0.0012127247,0.00006981545,0.0034733212],"study_design_scores_gemma":[0.0013877434,0.0003798218,0.17750338,0.00008544224,0.000027056121,0.000004894909,0.000055499637,0.0009231985,0.818595,0.00073369785,0.0001634081,0.00014088136],"about_ca_topic_score_codex":0.00036740565,"about_ca_topic_score_gemma":9.936551e-7,"teacher_disagreement_score":0.17474017,"about_ca_system_score_codex":0.000054074142,"about_ca_system_score_gemma":0.000097378164,"threshold_uncertainty_score":0.99975276},"labels":[],"label_agreement":null},{"id":"W2074982123","doi":"10.1139/bcb-2014-0115","title":"Isolation of autophagosome subpopulations after induction of autophagy by calcium","year":2014,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China; Purdue University","keywords":"Autophagosome; Autophagy; ATG5; Cell biology; Biogenesis; Cytosol; Biology; Phagosome; Organelle; Calcium; Membrane; Cytolysis; Chemistry; Biochemistry; Phagocytosis; Gene; Apoptosis; Cytotoxicity; Enzyme","score_opus":0.00882120086094509,"score_gpt":0.2571661127124922,"score_spread":0.24834491185154708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2074982123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99622184,0.001742859,0.00072394015,0.000056621368,0.00006363452,0.00006683025,0.000031993728,0.000014772603,0.0010774868],"genre_scores_gemma":[0.99887687,0.000051984753,0.0001980536,0.00006616478,0.000085223735,0.00000870275,0.00016551962,0.0000058236064,0.00054164033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994852,0.000024048544,0.00020277836,0.00015358711,0.000042536,0.000091864145],"domain_scores_gemma":[0.9996137,0.000022089494,0.00010768679,0.00015417922,0.000045430188,0.00005688635],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000061015322,0.000082522056,0.00018151972,0.00002742563,0.000019985056,0.00000128137,0.000029503633,0.00018544584,0.00013986141],"category_scores_gemma":[0.000017589586,0.000072397874,0.00004858487,0.00006045329,0.00012616534,0.000018383036,0.000013305575,0.000059758484,0.0000017567597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012323087,0.00010504305,0.008816116,0.000117095304,0.000019868541,3.2817726e-7,0.000033739852,4.3526916e-7,0.98899764,0.00010225683,0.00007780229,0.0016064348],"study_design_scores_gemma":[0.00062509696,0.00016770986,0.024566464,0.00001465847,0.000044809454,0.0000043200416,0.00001770078,0.00015110502,0.9732059,0.00029210976,0.000848965,0.00006112794],"about_ca_topic_score_codex":0.000016265174,"about_ca_topic_score_gemma":1.260949e-7,"teacher_disagreement_score":0.015791716,"about_ca_system_score_codex":0.000008367566,"about_ca_system_score_gemma":0.000025192538,"threshold_uncertainty_score":0.29522994},"labels":[],"label_agreement":null},{"id":"W2076166231","doi":"10.1074/jbc.m413957200","title":"Endothelial Nitric-oxide Synthase Antisense (NOS3AS) Gene Encodes an Autophagy-related Protein (APG9-like2) Highly Expressed in Trophoblast","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":132,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto; Hospital for Sick Children","funders":"","keywords":"Biology; Cell biology; Autophagy; Trophoblast; Autophagosome; Gene knockdown; Transfection; Gene; Vacuole; Cytoplasm; Molecular biology; Biochemistry; Genetics; Placenta","score_opus":0.016373030984055986,"score_gpt":0.2653383128623276,"score_spread":0.24896528187827163,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076166231","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99734086,0.0014969994,0.000048984188,0.0003171232,0.000043777156,0.00023693338,0.00005378208,0.000060521656,0.00040103638],"genre_scores_gemma":[0.99610883,0.0004222656,0.0021001527,0.00025342792,0.0006907257,0.000013154309,0.000022792334,0.000026320862,0.00036233058],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99777186,0.000120737626,0.0009785871,0.0003408104,0.0003622935,0.00042568822],"domain_scores_gemma":[0.9984823,0.00010088723,0.00048341654,0.0003138886,0.0001474532,0.00047206422],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003836484,0.00031440647,0.0007057684,0.00010073587,0.0000606152,0.000027020034,0.0002827493,0.000434613,0.00079722924],"category_scores_gemma":[0.00033148855,0.00021738808,0.000312924,0.00022857165,0.00017836594,0.00015692269,0.000041907344,0.00071956374,0.00002327704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019682844,0.001433011,0.0010680996,0.0000379334,0.00009924761,0.0029675022,0.000044534496,0.000057318106,0.9904333,0.0000070240762,0.000071938346,0.0018118533],"study_design_scores_gemma":[0.004955351,0.00046816867,0.0087348325,0.00020362447,0.00005555936,0.0009982077,0.00007360835,0.0002049685,0.98303676,0.00025592907,0.0007736085,0.00023939606],"about_ca_topic_score_codex":0.000006987363,"about_ca_topic_score_gemma":2.6309803e-7,"teacher_disagreement_score":0.0076667327,"about_ca_system_score_codex":0.0001616434,"about_ca_system_score_gemma":0.00022018768,"threshold_uncertainty_score":0.88648283},"labels":[],"label_agreement":null},{"id":"W2076267530","doi":"10.1016/j.semradonc.2013.05.006","title":"The Roles of Reactive Oxygen Species and Autophagy in Mediating the Tolerance of Tumor Cells to Cycling Hypoxia","year":2013,"lang":"en","type":"review","venue":"Seminars in Radiation Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Autophagy; Hypoxia (environmental); Reactive oxygen species; Cell biology; Medicine; Oxidative stress; Clearance; Cancer research; Glutathione; Oxygen; Biology; Apoptosis; Internal medicine; Biochemistry; Chemistry; Enzyme","score_opus":0.024143757071969054,"score_gpt":0.3489227042201672,"score_spread":0.32477894714819816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076267530","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.05921408,0.9381135,0.0000024524525,0.00024121175,0.0002637196,0.0014194142,0.000028533586,0.0000072721305,0.0007098213],"genre_scores_gemma":[0.0074787685,0.99148625,0.00023345575,0.00015298302,0.00018662229,0.00024902885,0.00002233477,0.000025405183,0.00016515353],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979897,0.00038751093,0.0009292821,0.0002611027,0.00019695055,0.00023544597],"domain_scores_gemma":[0.9962368,0.002503659,0.00081656483,0.00031513625,0.00006389975,0.00006394129],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008472717,0.00022014398,0.001285197,0.00023078307,0.000054818946,0.0000068864383,0.00022773683,0.0002103959,0.000023470397],"category_scores_gemma":[0.00047562047,0.00013360164,0.00013024748,0.0003885876,0.00019726096,0.000044048942,0.00006385712,0.00037863114,0.0000052622295],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000670635,0.00010217787,0.00013237729,0.0011003203,0.00008176618,0.000024101022,0.0031750796,0.00003457716,0.000725048,0.00021431503,0.00023975017,0.99410343],"study_design_scores_gemma":[0.0013227374,0.00063085055,0.0068625803,0.007926831,0.0003630048,0.000051445113,0.0024403443,0.00031585366,0.003498508,0.0003922211,0.97590595,0.00028969315],"about_ca_topic_score_codex":0.00003516208,"about_ca_topic_score_gemma":0.000049320017,"teacher_disagreement_score":0.99381375,"about_ca_system_score_codex":0.00027058108,"about_ca_system_score_gemma":0.0004569682,"threshold_uncertainty_score":0.5448117},"labels":[],"label_agreement":null},{"id":"W2076378891","doi":"10.1016/j.bbadis.2014.05.010","title":"The role of the autophagy in myocardial ischemia/reperfusion injury","year":2014,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":304,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Association of Optometrists; National Natural Science Foundation of China","keywords":"Autophagy; Ischemia; Reperfusion injury; Medicine; Organelle; Intracellular; Cell biology; Biology; Cardiology; Apoptosis; Biochemistry","score_opus":0.007330099618910661,"score_gpt":0.2907966593522356,"score_spread":0.2834665597333249,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076378891","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.36664516,0.6307248,0.0000016433223,0.0003415319,0.00017215799,0.0014156586,0.00030510564,0.000034645404,0.0003593045],"genre_scores_gemma":[0.40174758,0.5973017,0.00002249813,0.00029639262,0.00016698692,0.0001582475,0.00015222136,0.00011141813,0.000042927575],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9959376,0.0007214797,0.0011853111,0.0007549967,0.0009057847,0.00049481355],"domain_scores_gemma":[0.9957897,0.00023728356,0.0010371252,0.0024153276,0.00014507488,0.0003754629],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037844185,0.00075588975,0.0020503073,0.00021490124,0.00012588128,0.000034362118,0.0010963306,0.00037178193,0.000025601446],"category_scores_gemma":[0.0003193211,0.00044934632,0.002822913,0.000751985,0.0005418854,0.000058015496,0.00046847257,0.0006223409,0.000017254604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023810135,0.0033739544,0.000017809954,0.01665247,0.0034049093,0.00006869011,0.00020803459,0.0000022479994,0.51041055,0.0026699232,0.0012925952,0.45951778],"study_design_scores_gemma":[0.001375964,0.00031804357,0.00061850157,0.01120584,0.005864224,0.0000054926795,0.000030898216,0.000042119187,0.85362625,0.0007711423,0.1253219,0.0008196112],"about_ca_topic_score_codex":0.00002413918,"about_ca_topic_score_gemma":6.302484e-7,"teacher_disagreement_score":0.45869815,"about_ca_system_score_codex":0.0000994257,"about_ca_system_score_gemma":0.0013898148,"threshold_uncertainty_score":0.99979585},"labels":[],"label_agreement":null},{"id":"W2076953907","doi":"10.1089/rej.2006.0535","title":"Autophagy in the Heart and Liver During Normal Aging and Calorie Restriction","year":2007,"lang":"en","type":"article","venue":"Rejuvenation Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":178,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"National Cancer Institute; National Institute on Aging; National Institutes of Health","keywords":"Calorie restriction; Autophagy; Vacuole; Endocrinology; Senescence; Internal medicine; Biology; Cathepsin; Intracellular; Calorie; Cathepsin D; Cell biology; Medicine; Apoptosis; Biochemistry; Cytoplasm; Enzyme","score_opus":0.04642008746167046,"score_gpt":0.38624403151082903,"score_spread":0.33982394404915856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076953907","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99474233,0.0012784068,0.000036247282,0.0021240427,0.000025946652,0.00027392939,7.452044e-7,0.000017599194,0.0015007685],"genre_scores_gemma":[0.99862176,0.00063346425,0.000058448488,0.00021833705,0.00011783261,0.000011585516,0.0000043044606,0.0000070835504,0.00032720433],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989144,0.00012153188,0.00013045152,0.0001534862,0.00044047076,0.000239623],"domain_scores_gemma":[0.99944866,0.00024701134,0.00001570881,0.00012315705,0.00008681875,0.00007866837],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019178647,0.00005221864,0.00007635657,0.00030700586,0.00019196542,0.000032263797,0.00003882039,0.000054702334,0.00003187993],"category_scores_gemma":[0.00014151007,0.000039144663,0.000015145111,0.0004011752,0.000084935156,0.000108280285,0.000029488996,0.0003198968,0.000007259881],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022903087,0.00094580185,0.7462723,0.0007708182,0.00011530449,0.0026496844,0.013230739,0.000020610189,0.14949903,0.021615775,0.003149241,0.059440352],"study_design_scores_gemma":[0.0008758348,0.000085730186,0.988387,0.00004312642,0.0000038679555,0.000046284476,0.00044886622,0.00025918934,0.006682662,0.00026928427,0.0028586916,0.000039468843],"about_ca_topic_score_codex":0.00022009191,"about_ca_topic_score_gemma":0.000045108092,"teacher_disagreement_score":0.24211466,"about_ca_system_score_codex":0.00006607159,"about_ca_system_score_gemma":0.00004493577,"threshold_uncertainty_score":0.1596273},"labels":[],"label_agreement":null},{"id":"W2078252863","doi":"10.4161/auto.4054","title":"Nitric Oxide-Induced Cell Death in the Heart: The Role of Autophagy","year":2007,"lang":"en","type":"letter","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Autophagy; Biology; Nitric oxide; Programmed cell death; Cell biology; Apoptosis; Biochemistry; Endocrinology","score_opus":0.01924380881991246,"score_gpt":0.2799241046037985,"score_spread":0.2606802957838861,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078252863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89321893,0.012817336,0.000014170413,0.07007633,0.0003662207,0.0019474739,0.00004814927,0.0001442014,0.021367151],"genre_scores_gemma":[0.58876467,0.00013592758,0.00008583394,0.4069302,0.0015987041,0.00010102943,0.000112227695,0.00010208166,0.0021692864],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9959076,0.00042977248,0.00092471874,0.0006418788,0.0011723522,0.0009236899],"domain_scores_gemma":[0.996714,0.0008524005,0.000410861,0.0017799465,0.00013685066,0.00010597242],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00093965983,0.0006372539,0.0010215492,0.0005059344,0.00014849576,0.000042853353,0.0009751578,0.0010763877,0.00045585958],"category_scores_gemma":[0.00007934975,0.00037193135,0.0006253921,0.00086826674,0.00017220521,0.00007854272,0.00010069791,0.0029872213,0.000276191],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006291606,0.002184342,0.0035133301,0.001152987,0.0009450181,0.010503841,0.003497217,0.00001466478,0.06100067,0.0016251636,0.90372217,0.011211411],"study_design_scores_gemma":[0.0025145537,0.00041094774,0.08927374,0.00022360457,0.0005686968,0.00039761997,0.00030941403,0.00013937552,0.12246637,0.002968174,0.7801163,0.00061115733],"about_ca_topic_score_codex":0.0005024004,"about_ca_topic_score_gemma":0.0000068056115,"teacher_disagreement_score":0.3368539,"about_ca_system_score_codex":0.00014096992,"about_ca_system_score_gemma":0.0004977875,"threshold_uncertainty_score":0.9998733},"labels":[],"label_agreement":null},{"id":"W2078467208","doi":"10.1158/1538-7445.am2012-2477","title":"Abstract 2477: Autophagy is correlated with chemoresistance in neuroblastoma","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"","keywords":"Autophagy; ATG5; Vacuole; Autophagosome; Programmed cell death; Cancer research; Neuroblastoma; Biology; Cancer cell; Chemotherapy; Viability assay; Cell; Apoptosis; Cancer; Cell biology; Cell culture; Biochemistry","score_opus":0.061918235449249286,"score_gpt":0.40806119552599274,"score_spread":0.34614296007674344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078467208","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98746824,0.0049617416,0.000004053642,0.00093795673,0.00010347572,0.00039894527,0.000009202106,0.00005151224,0.0060648867],"genre_scores_gemma":[0.9952598,0.00047614283,0.000026787855,0.00065691717,0.00024355,0.00014427355,0.000006324741,0.0000423434,0.0031438123],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981404,0.00004970136,0.00017724576,0.00026729566,0.0006264796,0.00073888013],"domain_scores_gemma":[0.9990136,0.00008459558,0.000036237565,0.00038143984,0.00015389868,0.0003301965],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003864248,0.00013524004,0.00022338296,0.00020007284,0.000079567195,0.00001786218,0.00014118812,0.000095784395,0.0025411856],"category_scores_gemma":[0.000036840407,0.00010550699,0.000043534284,0.00069476635,0.0001926395,0.00014857423,0.000033382406,0.000660056,0.00023493671],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02084239,0.0040776106,0.3906197,0.0015556258,0.0006701703,0.0030600599,0.009283312,0.00008082272,0.4379694,0.0018196864,0.08327733,0.046743892],"study_design_scores_gemma":[0.0026140534,0.00019241247,0.8391646,0.0003407726,0.000015326492,0.000023326553,0.00011903087,0.00005228695,0.14750798,0.000074016585,0.009742296,0.000153892],"about_ca_topic_score_codex":0.00024182085,"about_ca_topic_score_gemma":0.000040369236,"teacher_disagreement_score":0.44854492,"about_ca_system_score_codex":0.00023968543,"about_ca_system_score_gemma":0.0003743629,"threshold_uncertainty_score":0.99837065},"labels":[],"label_agreement":null},{"id":"W2078705827","doi":"10.1371/journal.pone.0017682","title":"Critical Role of the Rb Family in Myoblast Survival and Fusion","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; U.S. Public Health Service","keywords":"Myogenesis; Myocyte; Autophagy; Cell biology; Biology; Programmed cell death; C2C12; Cancer research; Molecular biology; Genetics; Apoptosis","score_opus":0.05078810309393927,"score_gpt":0.25034998527072827,"score_spread":0.199561882176789,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078705827","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894802,0.0007779834,0.0000017631057,0.00015338602,0.000018388548,0.00011275461,0.0000040748155,0.000009715945,0.009441711],"genre_scores_gemma":[0.9994639,0.00010055065,0.0001444442,0.00016714494,0.000034706583,0.0000049169453,8.0229046e-7,0.0000068923296,0.00007659877],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999551,0.000027976725,0.00009782653,0.00008052324,0.0001554963,0.000087195935],"domain_scores_gemma":[0.9997207,0.000036955396,0.0000143699845,0.00014670302,0.000033579043,0.000047693724],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006345556,0.00004636975,0.00013485704,0.000023346303,0.000016728476,0.0000015532412,0.00004213599,0.000036737154,0.00013508003],"category_scores_gemma":[0.00007231149,0.00003115783,0.000022338436,0.000059013088,0.00008516789,0.000024305098,0.000031823125,0.00007850519,0.000007785186],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005479522,0.004584352,0.29776904,0.00017602029,0.000115372095,0.00002144835,0.0017358924,3.01589e-8,0.6874395,0.005696694,0.000025447242,0.0018882299],"study_design_scores_gemma":[0.00063927274,0.00014736144,0.85958564,0.00021618546,0.00006967925,8.6847183e-7,0.00031470566,0.00007633406,0.13654523,0.0023512505,0.000015295502,0.0000381822],"about_ca_topic_score_codex":0.000060750073,"about_ca_topic_score_gemma":0.000007982923,"teacher_disagreement_score":0.5618166,"about_ca_system_score_codex":0.000005811945,"about_ca_system_score_gemma":0.000021587384,"threshold_uncertainty_score":0.14790316},"labels":[],"label_agreement":null},{"id":"W2079408014","doi":"10.1016/j.niox.2006.10.007","title":"Nitric oxide differentially regulates the gene expression of caspase genes but not some autophagic genes","year":2006,"lang":"en","type":"article","venue":"Nitric Oxide","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Caspase; Programmed cell death; Gene; Autophagy; Gene expression; Apoptosis; Complementary DNA; Biology; Viability assay; DNA microarray; Cell biology; Microarray analysis techniques; Molecular biology; Microarray; Nitric oxide; Caspase 3; Genetics","score_opus":0.01255818520635204,"score_gpt":0.2418820769148353,"score_spread":0.22932389170848325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079408014","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97897655,0.019479407,0.00022123792,0.00018489624,0.000114627444,0.00057425787,0.000051008145,0.00016726823,0.00023073157],"genre_scores_gemma":[0.9924785,0.0009591203,0.001063449,0.0004908984,0.00066984055,0.000064480744,0.00008371124,0.000071681556,0.004118326],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99747014,0.0001473106,0.0007011331,0.00047395684,0.00069488597,0.00051258656],"domain_scores_gemma":[0.9981352,0.00024148141,0.0003483838,0.00090593076,0.00018036169,0.0001886204],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021680011,0.0003979504,0.0006156205,0.00033785737,0.00021967314,0.000033464497,0.000356394,0.00021707233,0.00024178522],"category_scores_gemma":[0.000060596172,0.00026057498,0.00036249525,0.0005248283,0.00019053128,0.00014218641,0.00011729908,0.00023596596,0.00006827838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036582514,0.00044176515,0.005110692,0.000094219606,0.00010548471,0.00021108658,0.000022382854,0.00008413538,0.98969346,0.00027317746,0.00073225534,0.0028655392],"study_design_scores_gemma":[0.0015944145,0.000047725567,0.26619038,0.000056516386,0.00026686685,0.00007156943,0.000038563772,0.00017665647,0.7297405,0.0012536244,0.0003585865,0.00020457555],"about_ca_topic_score_codex":0.0005453363,"about_ca_topic_score_gemma":0.0000043200375,"teacher_disagreement_score":0.2610797,"about_ca_system_score_codex":0.00007607218,"about_ca_system_score_gemma":0.00018048598,"threshold_uncertainty_score":0.9999846},"labels":[],"label_agreement":null},{"id":"W2080091995","doi":"10.1038/onc.2008.309","title":"The endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family","year":2008,"lang":"en","type":"review","venue":"Oncogene","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":262,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Endoplasmic reticulum; Autophagy; Biology; Cell biology; Apoptosis; Unfolded protein response; Mitochondrion; Signal transduction; Programmed cell death; Bcl-2 family; Genetics","score_opus":0.01706747120047008,"score_gpt":0.28742815834776775,"score_spread":0.27036068714729766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080091995","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.028479937,0.9664939,3.7389358e-7,0.000069042624,0.00010890998,0.0018365543,0.000030457148,0.000020014502,0.0029608267],"genre_scores_gemma":[0.0039972314,0.99411374,0.000041271254,0.000077573175,0.00012832179,0.00032409935,0.000013515646,0.000052119918,0.0012521201],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982968,0.00022117894,0.00057443406,0.00031038764,0.00032284964,0.00027435803],"domain_scores_gemma":[0.9987038,0.00012332213,0.00032717962,0.00071460236,0.000041369676,0.0000897418],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001781303,0.00032177544,0.0011030621,0.00007995033,0.00012398679,0.000011264479,0.00029092227,0.0002463417,0.000020609446],"category_scores_gemma":[0.00006972559,0.00015841353,0.00042547492,0.0003494896,0.00024665566,0.000021083817,0.000105033745,0.00037859965,0.000015568039],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003635124,0.00014307421,0.000017981993,0.0020344546,0.00026344668,0.000022708335,0.00009306975,1.2326855e-7,0.0016614997,0.00026559067,0.00023650497,0.9952252],"study_design_scores_gemma":[0.0006347744,0.00009813832,0.00009046855,0.006355644,0.0003608908,0.00010795491,0.000035788533,0.0000060483903,0.0084316945,0.00013891964,0.9835749,0.00016476767],"about_ca_topic_score_codex":0.00004713315,"about_ca_topic_score_gemma":0.0000066042476,"teacher_disagreement_score":0.99506044,"about_ca_system_score_codex":0.000078221856,"about_ca_system_score_gemma":0.00058248953,"threshold_uncertainty_score":0.6459917},"labels":[],"label_agreement":null},{"id":"W2080132037","doi":"10.1016/j.chom.2013.07.013","title":"A Deficiency in the Autophagy Gene Atg16L1 Enhances Resistance to Enteric Bacterial Infection","year":2013,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; Memorial Sloan-Kettering Cancer Center","keywords":"ATG16L1; Biology; Citrobacter rodentium; NOD2; Autophagy; Immune system; Gene; Mutant; Microbiology; Inflammatory bowel disease; Crohn's disease; Phenotype; Immunology; Innate immune system; Genetics; Disease; Apoptosis; Medicine","score_opus":0.00724497234178931,"score_gpt":0.24234021369890932,"score_spread":0.23509524135712,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080132037","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929547,0.0014565813,0.00018582486,0.00048545448,0.0003743575,0.00073561986,0.0000061885576,0.000044111588,0.0037571797],"genre_scores_gemma":[0.99479306,0.0002248122,0.00029837855,0.0019662874,0.00023371738,0.00013318831,0.00002164324,0.000018599376,0.0023102942],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895644,0.000072118535,0.00024626736,0.00028158384,0.0001396262,0.0003039499],"domain_scores_gemma":[0.99940926,0.000034286186,0.000066541834,0.00035093783,0.000051981315,0.00008696868],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001364239,0.00015970755,0.00019400577,0.000097111806,0.000084822816,0.000056311408,0.00015736083,0.00007066803,0.00093697343],"category_scores_gemma":[0.000016921027,0.00011502712,0.000082756844,0.00033519886,0.000048402515,0.0001032395,0.00003476943,0.00012940846,0.0007308381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001092354,0.00028673682,0.0009547401,0.000049054186,0.0000065724826,0.000021568505,0.001181766,8.1467164e-7,0.99213725,0.000017233633,0.004587388,0.000647636],"study_design_scores_gemma":[0.0010912655,0.00024083485,0.24452606,0.000076184704,0.000029412322,0.000018172183,0.00009689486,0.0000050430403,0.7157115,0.0000761564,0.03795622,0.00017225883],"about_ca_topic_score_codex":0.00017476504,"about_ca_topic_score_gemma":0.000070087815,"teacher_disagreement_score":0.27642575,"about_ca_system_score_codex":0.00007031846,"about_ca_system_score_gemma":0.000067115856,"threshold_uncertainty_score":0.9999763},"labels":[],"label_agreement":null},{"id":"W2080612183","doi":"10.4161/auto.26059","title":"Cleavage of sequestosome 1/p62 by an enteroviral protease results in disrupted selective autophagy and impaired NFKB signaling","year":2013,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; China Scholarship Council; National Natural Science Foundation of China","keywords":"Sequestosome 1; Biology; Autophagy; Cleavage (geology); Cell biology; Signal transduction; Protease; Biochemistry; Apoptosis; Enzyme","score_opus":0.010798218474316529,"score_gpt":0.2695678153680963,"score_spread":0.25876959689377976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080612183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99620533,0.0009437443,0.00006233077,0.0002512648,0.00007300754,0.0015246082,0.00008810924,0.00016854431,0.00068306946],"genre_scores_gemma":[0.99792296,0.00004891671,0.00036441936,0.0006611355,0.00008231659,0.0001769949,0.00015746994,0.00005812983,0.00052763225],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975941,0.00021955426,0.0007168697,0.0006090555,0.00033893954,0.00052145467],"domain_scores_gemma":[0.99863726,0.00011894501,0.0002478323,0.00047905478,0.0001281156,0.00038880281],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029760736,0.00034317496,0.0006254003,0.00023915297,0.00007436333,0.000037819867,0.00016492367,0.00020704312,0.0001246845],"category_scores_gemma":[0.00016617184,0.0003085014,0.00010918136,0.00036604606,0.00018826693,0.0005091887,0.00006179656,0.00032529357,0.00003311743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032843994,0.0025718296,0.016073657,0.00034352194,0.00034464602,0.00050406804,0.005931057,0.000020184913,0.9488813,0.00030152843,0.0029210367,0.018822761],"study_design_scores_gemma":[0.0087589,0.002390684,0.2530178,0.0002177425,0.0000869757,0.000052107807,0.0003133156,0.0027478065,0.7306945,0.00112975,0.00020218639,0.0003882425],"about_ca_topic_score_codex":0.0009878488,"about_ca_topic_score_gemma":0.00001223083,"teacher_disagreement_score":0.23694415,"about_ca_system_score_codex":0.0001186846,"about_ca_system_score_gemma":0.00016377315,"threshold_uncertainty_score":0.9999367},"labels":[],"label_agreement":null},{"id":"W2081323782","doi":"10.1016/j.clinre.2014.06.014","title":"High expression of Beclin-1 predicts favorable prognosis for patients with colorectal cancer","year":2014,"lang":"en","type":"article","venue":"Clinics and Research in Hepatology and Gastroenterology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Colorectal cancer; Medicine; Immunohistochemistry; Internal medicine; Oncology; Stage (stratigraphy); Clinical significance; Cancer; Overall survival; Autophagy; Microsatellite instability; Multivariate analysis; Survival analysis; Cancer research; Pathology; Gene; Biology; Apoptosis","score_opus":0.02809204791952666,"score_gpt":0.3565472282111837,"score_spread":0.328455180291657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081323782","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978812,0.00029046304,0.000067109475,0.0009507022,0.00009513391,0.0006561627,0.000039339655,0.0000070670258,0.000012841787],"genre_scores_gemma":[0.99797416,0.0009599367,0.0004624855,0.00025933638,0.000049447375,0.00023520709,0.00003476969,0.000011407538,0.000013224274],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99867254,0.00023863002,0.0002851986,0.0003034492,0.00012389956,0.00037625176],"domain_scores_gemma":[0.9990011,0.0004606406,0.00008453977,0.00011020126,0.00020603913,0.00013750428],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061444123,0.00009745657,0.00041533686,0.00015127903,0.00008054984,0.000003870573,0.00006065435,0.00017372952,0.000013156836],"category_scores_gemma":[0.00012318858,0.000067604524,0.000030035366,0.00006828546,0.0006052387,0.000031287032,0.000065697124,0.00026710008,2.7149358e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00904974,0.0005504876,0.98685384,0.00017708476,0.000048640883,0.0000058046294,0.00006737467,0.0000014421289,0.00013474106,0.00018660254,0.00013201451,0.0027922299],"study_design_scores_gemma":[0.009706429,0.013443834,0.97212964,0.00018044635,0.000040029376,0.000007797447,0.000028993985,0.0008723303,0.0013181515,0.0018586842,0.00036311886,0.000050529303],"about_ca_topic_score_codex":0.000043875832,"about_ca_topic_score_gemma":0.00007491936,"teacher_disagreement_score":0.014724181,"about_ca_system_score_codex":0.000010988754,"about_ca_system_score_gemma":0.00006138055,"threshold_uncertainty_score":0.27568322},"labels":[],"label_agreement":null},{"id":"W2082094906","doi":"10.1093/glycob/cws093","title":"Concanavalin-A-induced autophagy biomarkers requires membrane type-1 matrix metalloproteinase intracellular signaling in glioblastoma cells","year":2012,"lang":"en","type":"article","venue":"Glycobiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Autophagy; Cell biology; Signal transduction; Vacuole; Chemistry; ATG5; Cancer cell; Gene silencing; Biology; Apoptosis; Biochemistry; Cytoplasm; Cancer; Gene","score_opus":0.01858551952690933,"score_gpt":0.2941427119152628,"score_spread":0.27555719238835347,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082094906","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99202067,0.0052575516,0.00002463018,0.0002197343,0.0011077309,0.00066194165,0.000013382254,0.00013760036,0.00055676355],"genre_scores_gemma":[0.997915,0.000109456894,0.00049930037,0.0005287928,0.00045818582,0.00004561793,0.000044439705,0.00005061264,0.00034856182],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99779516,0.00026284094,0.0005438686,0.0004035341,0.0001712717,0.0008233277],"domain_scores_gemma":[0.9988054,0.00014921068,0.00016687161,0.00044899347,0.00007888147,0.00035063928],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000604204,0.0003239438,0.00064781785,0.0003042446,0.0000688716,0.000011119193,0.00018076309,0.0003871156,0.0012635713],"category_scores_gemma":[0.00011206526,0.00028163247,0.00016927968,0.00044558212,0.00016340177,0.00013609273,0.00006145227,0.00031192097,0.0003838858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016036859,0.00029397846,0.0009777601,0.000077260476,0.00032211747,0.0004307691,0.00020807686,0.0000059566073,0.99405676,0.0007872047,0.00017594315,0.0010605073],"study_design_scores_gemma":[0.0026257117,0.00076883036,0.0007100425,0.00005903567,0.00016312249,0.00015284806,0.00015814818,0.00009540691,0.9902368,0.00017827853,0.0045547034,0.0002970631],"about_ca_topic_score_codex":0.00022561854,"about_ca_topic_score_gemma":0.000016366334,"teacher_disagreement_score":0.0058943667,"about_ca_system_score_codex":0.00015358672,"about_ca_system_score_gemma":0.00018626067,"threshold_uncertainty_score":0.9999636},"labels":[],"label_agreement":null},{"id":"W2082417169","doi":"10.4161/auto.7.9.16435","title":"Bacterial toxins can inhibit host cell autophagy through cAMP generation","year":2011,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Autophagy; Biology; Phagosome; Cell biology; Effector; Innate immune system; Immune system; Microbiology; ATG16L1; Autophagosome; Phagocytosis; Biochemistry; Immunology; Apoptosis","score_opus":0.040947322534233846,"score_gpt":0.26094628153298804,"score_spread":0.2199989589987542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082417169","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9722681,0.000777283,0.00036317343,0.00018912373,0.0013695268,0.0005868658,0.00006144041,0.00032489395,0.024059566],"genre_scores_gemma":[0.98833644,0.00017733444,0.0019676187,0.0026308813,0.0014930881,0.00007512031,0.00024210427,0.0000860221,0.0049914164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979095,0.00008752102,0.0004969329,0.00057693454,0.00036324133,0.0005659085],"domain_scores_gemma":[0.99867153,0.000024867268,0.00017420793,0.0007129658,0.00012242906,0.00029396886],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00013523165,0.00037861202,0.0004785678,0.00011072964,0.00019349503,0.000041717078,0.00019709115,0.00027056565,0.0068964027],"category_scores_gemma":[0.000030849267,0.00034367392,0.0002306359,0.00025034155,0.00012955378,0.00026233736,0.00007036598,0.00025994916,0.0006478814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004957477,0.0014029018,0.00064368657,0.0001051086,0.00024302753,0.00083541934,0.00836669,0.0000023361035,0.97111934,0.0046626064,0.008309305,0.0038138335],"study_design_scores_gemma":[0.0031995592,0.0006225155,0.023689069,0.00003314989,0.00016987394,0.00007875161,0.00009914137,0.00016054949,0.95653325,0.00050319976,0.014524361,0.0003865807],"about_ca_topic_score_codex":0.00045221945,"about_ca_topic_score_gemma":0.000056966117,"teacher_disagreement_score":0.023045382,"about_ca_system_score_codex":0.00013698313,"about_ca_system_score_gemma":0.00035965687,"threshold_uncertainty_score":0.99990153},"labels":[],"label_agreement":null},{"id":"W2082637970","doi":"10.1111/j.1600-0854.2008.00701.x","title":"The Itinerary of Autophagosomes: From Peripheral Formation to Kiss‐and‐Run Fusion with Lysosomes","year":2008,"lang":"en","type":"article","venue":"Traffic","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":432,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; University of California, San Diego; Institute of Genetics; Wellcome Trust","keywords":"Biology; KISS (TNC); Cell biology; Autophagy; Fusion; Biochemistry; Apoptosis","score_opus":0.012637483867234829,"score_gpt":0.2382616276644396,"score_spread":0.22562414379720477,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082637970","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959599,0.0022878197,0.00006833614,0.0007978225,0.00004531346,0.00027335912,0.000008297372,0.00007067868,0.00048846647],"genre_scores_gemma":[0.9978911,0.0006729707,0.00033649628,0.00042752034,0.00010688995,0.0000169493,0.000028822304,0.000014731578,0.00050449197],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99933416,0.000022766015,0.00017550318,0.00012486182,0.00020434256,0.00013835137],"domain_scores_gemma":[0.9995406,0.000056913403,0.000052694562,0.00020136054,0.000041313633,0.00010711134],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000043705913,0.0001067193,0.00017700231,0.000039573035,0.00014911058,0.000007777497,0.00006227105,0.000039451694,0.000101348516],"category_scores_gemma":[0.000009142966,0.00006127616,0.00004546434,0.00011641668,0.000086684864,0.000086843065,0.000013392378,0.00007142194,0.0000157469],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018364178,0.0028361832,0.023236481,0.0006379036,0.0015908367,0.0011120326,0.09318965,0.003503704,0.13216937,0.0034983098,0.019615993,0.7002454],"study_design_scores_gemma":[0.011669727,0.0034795615,0.9000261,0.00063824805,0.00030590716,0.000419869,0.0027224259,0.012143334,0.047938846,0.00027084397,0.01973847,0.00064667],"about_ca_topic_score_codex":0.000014405345,"about_ca_topic_score_gemma":0.0000065669947,"teacher_disagreement_score":0.8767896,"about_ca_system_score_codex":0.000017653789,"about_ca_system_score_gemma":0.00005811798,"threshold_uncertainty_score":0.24987693},"labels":[],"label_agreement":null},{"id":"W2083660113","doi":"10.3390/ijms14022529","title":"Regulation of Phosphatidylethanolamine Homeostasis — The Critical Role of CTP:Phosphoethanolamine Cytidylyltransferase (Pcyt2)","year":2013,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":111,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"Biology; Phosphatidylethanolamine; Cell biology; Diacylglycerol kinase; Biochemistry; Lipid metabolism; Lipogenesis; Signal transduction; Phospholipid; Protein kinase C; Phosphatidylcholine","score_opus":0.009644210618676178,"score_gpt":0.28797362546617217,"score_spread":0.278329414847496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083660113","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9877049,0.0053340485,0.0020199895,0.0038507362,0.00026333236,0.00013942132,0.000009228235,0.000004685844,0.000673672],"genre_scores_gemma":[0.9976128,0.0002779707,0.0016176049,0.00036356863,0.00008960589,0.0000036985512,0.000002561948,0.000007703129,0.000024528528],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979177,0.000058329613,0.0005778441,0.00012133383,0.0011887577,0.00013603021],"domain_scores_gemma":[0.99814856,0.00017855506,0.00030997914,0.00014621257,0.0011300236,0.0000866827],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046930436,0.000105648345,0.00024798207,0.00020231224,0.000039832976,0.000029150568,0.000489297,0.000048960686,0.0005256972],"category_scores_gemma":[0.00030435165,0.00006679688,0.00021516903,0.00027020305,0.000595012,0.00026932516,0.00003193247,0.00012414726,0.000004702168],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021283097,0.00037012165,0.0029195868,0.000023451556,0.00024997874,0.000041207557,0.0005293535,0.00012918553,0.9588552,0.008354309,0.00006367683,0.028251098],"study_design_scores_gemma":[0.0008254343,0.0005663082,0.058276746,0.00015184918,0.000078762685,0.00016132237,0.00041889393,0.00067152403,0.93202174,0.006607496,0.00015425975,0.00006569649],"about_ca_topic_score_codex":0.00006457278,"about_ca_topic_score_gemma":9.557128e-7,"teacher_disagreement_score":0.05535716,"about_ca_system_score_codex":0.000029187499,"about_ca_system_score_gemma":0.00021473899,"threshold_uncertainty_score":0.5756016},"labels":[],"label_agreement":null},{"id":"W2084693908","doi":"10.1038/nrmicro3160","title":"Bacteria–autophagy interplay: a battle for survival","year":2014,"lang":"en","type":"review","venue":"Nature Reviews Microbiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":565,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Burroughs Wellcome Fund; University of Toronto; Ontario Innovation Trust; Arthritis Society; Hospital for Sick Children","keywords":"Biology; Autophagy; Battle; Bacteria; Microbiology; Computational biology; Virology; Evolutionary biology; Genetics","score_opus":0.03383017190436507,"score_gpt":0.40960526540934233,"score_spread":0.3757750935049773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084693908","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000045062984,0.9900223,0.00021086136,0.000070690156,0.0049326005,0.003768401,0.00050145714,0.00009459383,0.00039460248],"genre_scores_gemma":[0.0000021489816,0.9881813,0.0011372283,0.0012084149,0.0021709104,0.0006709752,0.0048300815,0.00015504545,0.0016438937],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99627054,0.0006731031,0.0013910731,0.0009715263,0.000060662154,0.00063309394],"domain_scores_gemma":[0.996763,0.00094393454,0.0008738527,0.0010820143,0.00012693917,0.00021026886],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008971826,0.00092538283,0.0069708684,0.00025109254,0.00007594245,0.000021770444,0.0005133004,0.0026570812,0.00078173645],"category_scores_gemma":[0.0006283315,0.0005976495,0.0026809552,0.0002526763,0.00014323136,0.000030966417,0.000116077,0.0016096763,0.0009218245],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006587774,0.00011056714,4.5751952e-7,0.04888164,0.0006189943,0.000018195415,0.0000082178885,1.9169675e-9,0.00029289207,0.00042816787,0.03469255,0.9148824],"study_design_scores_gemma":[0.00077916426,0.0003013205,0.0000010466474,0.017895013,0.0024610239,0.00069779885,6.9716504e-7,2.6419403e-7,0.000041899937,0.00002451265,0.9773117,0.00048557972],"about_ca_topic_score_codex":0.0000010786091,"about_ca_topic_score_gemma":0.0000022352042,"teacher_disagreement_score":0.94261914,"about_ca_system_score_codex":0.00017145889,"about_ca_system_score_gemma":0.00037541214,"threshold_uncertainty_score":0.99985605},"labels":[],"label_agreement":null},{"id":"W2085771011","doi":"10.4161/auto.5.2.7348","title":"Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis","year":2009,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":149,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute on Drug Abuse; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institutes of Health; Tokyo Medical and Dental University; National Multiple Sclerosis Society; Dalhousie University; U.S. Department of Veterans Affairs","keywords":"Multiple sclerosis; Experimental autoimmune encephalomyelitis; ATG5; Biology; Immunology; Autophagy; Central nervous system; Encephalomyelitis; Downregulation and upregulation; Gene; Endocrinology; Apoptosis","score_opus":0.02439670510418357,"score_gpt":0.26730922727884354,"score_spread":0.24291252217465997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085771011","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955038,0.0027775578,0.00013350112,0.00059687224,0.00006627204,0.00029672496,0.000002732143,0.00013866345,0.0004838669],"genre_scores_gemma":[0.99747604,0.00042274583,0.00066575536,0.0009674486,0.00005552556,0.0000099892095,0.000034770575,0.00001472268,0.0003530114],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990461,0.000042411462,0.00025863326,0.00025386797,0.00017243242,0.00022656057],"domain_scores_gemma":[0.9995252,0.000049028,0.00006198996,0.00022595964,0.00004007934,0.00009774337],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013863278,0.00014113012,0.00023981924,0.00014647937,0.000064736196,0.0000155579,0.000058270107,0.000121421326,0.00012949566],"category_scores_gemma":[0.000083437444,0.00012496054,0.000048863676,0.0002225957,0.000034116067,0.00013806827,0.000018779132,0.00014435481,0.00002950733],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030192762,0.00038118515,0.00707892,0.000020767176,0.000016822045,0.000065928,0.00042997883,0.000018175082,0.915291,0.0002450285,0.00021183494,0.07593844],"study_design_scores_gemma":[0.0029533184,0.00017161001,0.77230644,0.00015483522,0.000016423064,0.000010016602,0.000025461986,0.0031350655,0.21994278,0.00069234846,0.0004872308,0.00010443651],"about_ca_topic_score_codex":0.000021412583,"about_ca_topic_score_gemma":0.0000018458372,"teacher_disagreement_score":0.76522756,"about_ca_system_score_codex":0.00004970374,"about_ca_system_score_gemma":0.00003816858,"threshold_uncertainty_score":0.5095743},"labels":[],"label_agreement":null},{"id":"W2086604883","doi":"10.1155/2011/470597","title":"When Cells Suffocate: Autophagy in Cancer and Immune Cells under Low Oxygen","year":2011,"lang":"en","type":"article","venue":"International Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria; BC Cancer Agency","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"Autophagy; Immune system; Tumor microenvironment; Cancer cell; Hypoxia (environmental); Cell biology; Effector; Cancer research; Antigen presentation; Downregulation and upregulation; Biology; Cell; Cancer; Chemistry; Immunology; T cell; Apoptosis; Oxygen; Biochemistry","score_opus":0.020813615936596332,"score_gpt":0.29220835021394137,"score_spread":0.27139473427734506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086604883","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99196595,0.0038171746,0.00018531381,0.00046823116,0.001262791,0.00008157948,0.000012432394,0.0000064840287,0.0022000377],"genre_scores_gemma":[0.99528605,0.0022007592,0.0005404562,0.0010397817,0.0002717942,0.0000031528539,0.0000049958267,0.000012894557,0.00064014236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990915,0.000046650814,0.0004346956,0.00013020942,0.00013769577,0.00015924397],"domain_scores_gemma":[0.9992982,0.0000479452,0.00026123747,0.000090923626,0.00020042284,0.0001012507],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00017845501,0.00011622875,0.0002701201,0.00022507744,0.000012843773,0.000008059973,0.00021626943,0.0001135431,0.0013229211],"category_scores_gemma":[0.000007131813,0.00009028713,0.000097062664,0.000041971725,0.00009946337,0.00007697978,0.000043747907,0.00021153358,0.000023363833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010578347,0.0005391856,0.003976675,0.00002004907,0.00029497998,0.00040197858,0.001022765,0.000019403278,0.9862512,0.0005890404,0.00031905193,0.0055078664],"study_design_scores_gemma":[0.0031557814,0.00038869565,0.054875575,0.00008385971,0.000049189617,0.00009245512,0.00010967085,0.00007074444,0.9330782,0.005595523,0.002387741,0.00011255189],"about_ca_topic_score_codex":0.00019458642,"about_ca_topic_score_gemma":0.000010989722,"teacher_disagreement_score":0.053172957,"about_ca_system_score_codex":0.0000801635,"about_ca_system_score_gemma":0.00015617641,"threshold_uncertainty_score":0.99959},"labels":[],"label_agreement":null},{"id":"W2087209616","doi":"10.1016/j.virol.2010.05.032","title":"Autophagy protein ATG5 interacts transiently with the hepatitis C virus RNA polymerase (NS5B) early during infection","year":2010,"lang":"en","type":"article","venue":"Virology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":154,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; Armand-Frappier Foundation","keywords":"NS5B; Biology; Virology; ATG5; Autophagy; Polymerase; RNA polymerase; Hepatitis C virus; RNA; RNA-dependent RNA polymerase; Virus; Hepacivirus; Enzyme; Biochemistry; Gene; Apoptosis","score_opus":0.003946419203451887,"score_gpt":0.22731687257450772,"score_spread":0.22337045337105582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087209616","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99674994,0.00012248803,0.00012608606,0.0015070016,0.00026633064,0.00055900833,0.0000076831,0.00025777618,0.00040369204],"genre_scores_gemma":[0.9977228,0.00003578899,0.000047387242,0.0012494334,0.00031036403,0.00013673374,0.000007313826,0.00005704738,0.00043311494],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99901015,0.000077120996,0.00017776835,0.00026752197,0.00015641071,0.00031101966],"domain_scores_gemma":[0.9993248,0.00003557384,0.00008637538,0.00037164427,0.000042262367,0.00013934285],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000087369815,0.00017281968,0.0002329425,0.00010405984,0.00016264735,0.000019562372,0.00009274623,0.00014873498,0.0003526896],"category_scores_gemma":[0.000020816447,0.00011523632,0.00008481727,0.00014748037,0.00019756479,0.00011775925,0.000019022447,0.00053471414,0.00014092744],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012189568,0.00023133469,0.006703313,0.000024897488,0.00014827213,0.00041004663,0.00074070896,0.0000028351062,0.9857305,0.0002635861,0.000045526052,0.0044800206],"study_design_scores_gemma":[0.0015657342,0.0007110002,0.61450016,0.000017705184,0.000065846,0.00021826767,0.0000041236976,0.0000384964,0.38133243,0.000053094987,0.0013928323,0.000100297075],"about_ca_topic_score_codex":0.0019094764,"about_ca_topic_score_gemma":0.0014477271,"teacher_disagreement_score":0.60779685,"about_ca_system_score_codex":0.000020580033,"about_ca_system_score_gemma":0.00007027411,"threshold_uncertainty_score":0.46992007},"labels":[],"label_agreement":null},{"id":"W2087484352","doi":"10.1155/2012/931956","title":"Forms, Crosstalks, and the Role of Phospholipid Biosynthesis in Autophagy","year":2012,"lang":"en","type":"article","venue":"International Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; Lysosome; Cytosol; Cytoplasm; Biology; Chemistry; Biochemistry; Apoptosis; Enzyme","score_opus":0.005363171376494233,"score_gpt":0.27317939726463525,"score_spread":0.267816225888141,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087484352","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9853784,0.010731435,0.000029610801,0.0004247602,0.00031188937,0.00005637379,0.000007782942,0.0000020746438,0.003057678],"genre_scores_gemma":[0.9980342,0.0011782545,0.00015370865,0.00034016196,0.00023647839,0.0000015153504,0.0000024076019,0.000005059452,0.00004822552],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999354,0.00004546299,0.0003274427,0.000046055055,0.000115367824,0.00011166543],"domain_scores_gemma":[0.9993398,0.00017562327,0.00024971706,0.00006352416,0.00011500134,0.00005629214],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003714115,0.00006321833,0.00021482249,0.000112690694,0.000011280844,0.0000046112855,0.00013728079,0.00005851285,0.00016351395],"category_scores_gemma":[0.000073386735,0.000035386918,0.00009624041,0.00003836112,0.00018770459,0.000074280106,0.000030415848,0.00011195724,0.000003635839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008831333,0.0012413244,0.29050428,0.000030408679,0.0007391615,0.000056055887,0.0027547213,0.000006119264,0.5620315,0.03433705,0.00012556004,0.099342465],"study_design_scores_gemma":[0.005717096,0.00020240058,0.0981,0.00005192265,0.000060745402,0.00026451403,0.00034256876,0.000069551694,0.8627233,0.009043289,0.023356453,0.0000681759],"about_ca_topic_score_codex":0.000026766771,"about_ca_topic_score_gemma":0.0000012111543,"teacher_disagreement_score":0.30069175,"about_ca_system_score_codex":0.000025806195,"about_ca_system_score_gemma":0.000049907583,"threshold_uncertainty_score":0.17903632},"labels":[],"label_agreement":null},{"id":"W2088497283","doi":"10.4161/auto.6.6.12623","title":"Immunoamphisomes in dendritic cells amplify TLR signaling and enhance exogenous antigen presentation on MHC-II","year":2010,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Autophagy; Biology; Innate immune system; Cell biology; Antigen presentation; Acquired immune system; Immune system; Dendritic cell; Pattern recognition receptor; TLR7; MHC class I; Toll-like receptor; Major histocompatibility complex; Antigen processing; Immunology; T cell; Apoptosis; Genetics","score_opus":0.009202366715473326,"score_gpt":0.28815831188352775,"score_spread":0.27895594516805444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2088497283","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99655217,0.0014380486,0.00006126538,0.00015503948,0.00038590704,0.00041084332,0.000008149428,0.00007603597,0.0009125666],"genre_scores_gemma":[0.9975405,0.00028967913,0.00034550382,0.000675375,0.00018689923,0.00003488748,0.000026976399,0.00003257468,0.0008676601],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988204,0.000042159474,0.00027312347,0.0003325182,0.00022012799,0.00031164178],"domain_scores_gemma":[0.9993144,0.00012221248,0.00007257281,0.00032642935,0.00004048007,0.00012387299],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001528276,0.0001806781,0.0002715097,0.00015714591,0.00013746055,0.00002761121,0.00009965691,0.00014554858,0.00038504164],"category_scores_gemma":[0.000040603732,0.00016946821,0.00005699029,0.00015286617,0.00008980327,0.00011109996,0.00003576386,0.00033743412,0.000079329024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014354497,0.0003308457,0.0023547066,0.000048247995,0.000046421872,0.00018344367,0.0011960587,0.000011989503,0.98611075,0.0005532767,0.00008163086,0.008939106],"study_design_scores_gemma":[0.0014131669,0.0003415244,0.09720194,0.00008215253,0.000032436554,0.0000401799,0.000111434245,0.00020160405,0.89798325,0.0009988552,0.0014056626,0.00018775942],"about_ca_topic_score_codex":0.00009469101,"about_ca_topic_score_gemma":0.000024379315,"teacher_disagreement_score":0.09484724,"about_ca_system_score_codex":0.000026825252,"about_ca_system_score_gemma":0.000074811316,"threshold_uncertainty_score":0.69107133},"labels":[],"label_agreement":null},{"id":"W2089558173","doi":"10.4161/cc.26885","title":"Macromitophagy, neutral lipids synthesis, and peroxisomal fatty acid oxidation protect yeast from “liponecrosis”, a previously unknown form of programmed cell death","year":2013,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University; Royal Military College of Canada; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Programmed cell death; Biology; Cell biology; Autophagy; Propidium iodide; Apoptosis; Cell; Apoptosome; Mitochondrion; Vacuole; Biochemistry; Cytoplasm; Caspase","score_opus":0.009139064278433924,"score_gpt":0.2264175009182897,"score_spread":0.21727843663985577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089558173","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949593,0.0015909106,0.00017652429,0.0001102734,0.00008578983,0.0019537366,0.00002468281,0.00010591278,0.0009928575],"genre_scores_gemma":[0.9958307,0.00023681375,0.0028085993,0.00010892274,0.00018934124,0.0005135891,0.000059008195,0.000051179464,0.00020185947],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985406,0.00006499939,0.00036539408,0.0004009087,0.00021447419,0.00041365973],"domain_scores_gemma":[0.99894786,0.000055462155,0.00017868003,0.00043037912,0.00009604499,0.0002915976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011596903,0.00026488738,0.0004295463,0.00007108643,0.00009623597,0.000055239874,0.00014614657,0.00017399827,0.00040252754],"category_scores_gemma":[0.000029961422,0.00022267921,0.00015717075,0.00011982795,0.00011624749,0.00021043816,0.00005957378,0.00018168596,0.000086560074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030644206,0.0009033231,0.011299323,0.00038209584,0.000084552434,0.000011519891,0.0008529387,0.0000011858446,0.96493727,0.00002940315,0.00015698178,0.021034956],"study_design_scores_gemma":[0.001871809,0.00035346675,0.119861834,0.00011871455,0.0001535085,0.000006584756,0.00012484065,0.00038041125,0.8761623,0.00045373212,0.00031537944,0.0001974425],"about_ca_topic_score_codex":0.0005038918,"about_ca_topic_score_gemma":0.000012191145,"teacher_disagreement_score":0.10856251,"about_ca_system_score_codex":0.00004870874,"about_ca_system_score_gemma":0.00009184223,"threshold_uncertainty_score":0.9080595},"labels":[],"label_agreement":null},{"id":"W2089596096","doi":"10.1089/adt.2013.561","title":"Development of Fluorescent Substrates and Assays for the Key Autophagy-Related Cysteine Protease Enzyme, ATG4B","year":2014,"lang":"en","type":"article","venue":"Assay and Drug Development Technologies","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Drug Research and Development; Structural Genomics Consortium; Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Förster resonance energy transfer; Chemistry; Cysteine protease; Protease; Drug discovery; Biochemistry; Cysteine; Cleavage (geology); Enzyme; Biophysics; Fluorescence; Biology","score_opus":0.012125142826016714,"score_gpt":0.24084849220754717,"score_spread":0.22872334938153047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089596096","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98731023,0.0061403806,0.002396986,0.0018202013,0.00008690957,0.0014418367,0.0000051474303,0.0005242089,0.00027407074],"genre_scores_gemma":[0.97153616,0.0003420576,0.027240884,0.00008242774,0.000012969442,0.00037008795,0.000026958849,0.00002207657,0.00036640192],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984894,0.000033179345,0.00053492456,0.00036963416,0.0002491167,0.00032378643],"domain_scores_gemma":[0.9990207,0.0002841174,0.00018402077,0.0003252588,0.00011318053,0.00007274231],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009466962,0.00027358226,0.00038954386,0.0001454401,0.00033219357,0.000028188098,0.00018242835,0.00018464803,0.000009435149],"category_scores_gemma":[0.00031434384,0.0001728355,0.00005075635,0.00018651604,0.00030694457,0.00006925611,0.00014597872,0.00018561615,0.000005031153],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005302325,0.0005485623,0.011459905,0.0010067308,0.0011703456,0.000021395235,0.0057141995,0.000006269797,0.039769493,0.017341405,0.0010904839,0.921341],"study_design_scores_gemma":[0.0025129276,0.00013385255,0.029715326,0.00030857377,0.00011104116,0.000022793482,0.0017796546,0.00062628026,0.9293982,0.002212031,0.03285187,0.00032745177],"about_ca_topic_score_codex":0.0000039215774,"about_ca_topic_score_gemma":0.000007855042,"teacher_disagreement_score":0.92101353,"about_ca_system_score_codex":0.000039932074,"about_ca_system_score_gemma":0.00022098125,"threshold_uncertainty_score":0.7048027},"labels":[],"label_agreement":null},{"id":"W2090246342","doi":"10.1016/j.semcdb.2015.03.005","title":"Autophagy in neurodegenerative diseases: From pathogenic dysfunction to therapeutic modulation","year":2015,"lang":"en","type":"review","venue":"Seminars in Cell and Developmental Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":110,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Infection and Immunity","keywords":"Autophagy; Neurodegeneration; Biology; Neuroscience; Mechanism (biology); Cell biology; Intracellular; Programmed cell death; Disease; Apoptosis; Medicine; Genetics; Pathology","score_opus":0.03422626185024109,"score_gpt":0.3187730318630194,"score_spread":0.28454677001277834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090246342","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06461982,0.9333613,0.000026372081,0.000016671114,0.00033688132,0.001182402,0.00013082575,0.000026894455,0.000298855],"genre_scores_gemma":[0.015862152,0.9806082,0.00049668876,0.0004356242,0.00011914584,0.00031598916,0.0017926643,0.000038964325,0.0003305224],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981405,0.00024351229,0.0005709565,0.0006496932,0.00011283398,0.00028249665],"domain_scores_gemma":[0.9993531,0.00012311112,0.00012606142,0.00017759645,0.000026466401,0.0001936381],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016871488,0.0003852194,0.0011448325,0.00034623922,0.00003505572,0.000010824621,0.00009618396,0.00035670883,0.00009661597],"category_scores_gemma":[0.000027239115,0.00030590672,0.000104721046,0.00035247402,0.000058613925,0.00004142738,0.00009795189,0.00025703642,0.0000786569],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015245411,0.0001864966,0.0016184835,0.00051924004,0.00006034227,0.00012776951,0.0005638936,0.0000015638697,0.0003993058,0.000012380976,0.00013473506,0.99622333],"study_design_scores_gemma":[0.005368225,0.001357191,0.021330511,0.00964965,0.00083009043,0.00018591323,0.00084623264,0.0002005636,0.000578238,0.002934674,0.9549061,0.0018126029],"about_ca_topic_score_codex":0.000044559838,"about_ca_topic_score_gemma":0.000018569574,"teacher_disagreement_score":0.99441075,"about_ca_system_score_codex":0.00038400758,"about_ca_system_score_gemma":0.0005782316,"threshold_uncertainty_score":0.9999393},"labels":[],"label_agreement":null},{"id":"W2090914871","doi":"10.1038/cr.2014.79","title":"Phosphorylated ubiquitin: a new shade of PINK1 in Parkin activation","year":2014,"lang":"en","type":"article","venue":"Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Parkin; PINK1; Biology; Ubiquitin ligase; Ubiquitin; Autophagy; Mitophagy; Ubiquitin-Protein Ligases; Mitochondrion; Cell biology; Phosphorylation; Parkinson's disease; Biochemistry; Disease; Apoptosis; Internal medicine; Gene","score_opus":0.06898113838241984,"score_gpt":0.3900354387328999,"score_spread":0.3210543003504801,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090914871","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96957743,0.00043353206,0.00009314586,0.00058903237,0.000021055355,0.00030238784,6.986635e-7,0.000018187073,0.028964553],"genre_scores_gemma":[0.9938031,0.00012339349,0.000087694774,0.00013728692,0.0001030359,0.000013010836,0.000015317279,0.000015962956,0.0057011987],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99879724,0.00013026573,0.00018204824,0.00017854162,0.00042978654,0.00028209537],"domain_scores_gemma":[0.9992121,0.0002037046,0.000033620716,0.0002787341,0.000115830626,0.00015604401],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000723397,0.00006678419,0.00016728882,0.00021902841,0.000029531233,0.000007828507,0.000109766246,0.000091133596,0.00070812413],"category_scores_gemma":[0.00017877022,0.000059058424,0.00004125766,0.00048420465,0.000071278264,0.0000412152,0.000035646437,0.0003191882,0.00009307242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021664826,0.00098791,0.012135512,0.00040906505,0.000053579486,0.00004430779,0.0019090475,0.000029697483,0.8539864,0.0014457833,0.020986792,0.10584545],"study_design_scores_gemma":[0.002269158,0.00038564377,0.04639846,0.00016740747,0.000006120647,9.510489e-7,0.00011375482,0.0008512474,0.92885834,0.002148858,0.018734673,0.00006536867],"about_ca_topic_score_codex":0.0003151448,"about_ca_topic_score_gemma":0.0000050556837,"teacher_disagreement_score":0.10578009,"about_ca_system_score_codex":0.00005915973,"about_ca_system_score_gemma":0.00031015143,"threshold_uncertainty_score":0.7753463},"labels":[],"label_agreement":null},{"id":"W2091169789","doi":"10.1016/j.chom.2009.09.006","title":"Autophagy Induction by the Pathogen Receptor CD46","year":2009,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":254,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Global Obesity Prevention Center, Johns Hopkins University; Institut National Du Cancer; Institute of Cancer Research; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Autophagy; Biology; Cell biology; Intracellular; BAG3; Innate immune system; Pathogen; CD46; Intracellular parasite; Receptor; Microbiology; Immune system; Immunology; Apoptosis; Biochemistry; Complement system","score_opus":0.00674727072941287,"score_gpt":0.238299331411493,"score_spread":0.23155206068208015,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091169789","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9804965,0.008450951,0.00010068942,0.00249795,0.000386695,0.0004155537,0.000040508854,0.00012738162,0.007483756],"genre_scores_gemma":[0.9760853,0.0005558511,0.00024356405,0.0070428676,0.0004950145,0.0000130229155,0.00017779246,0.000029666704,0.015356931],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999096,0.000046792717,0.00019246117,0.00025618856,0.00014184914,0.0002667588],"domain_scores_gemma":[0.99932027,0.000019175892,0.00007650966,0.00041028435,0.000050777995,0.00012298365],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000121000776,0.00016865924,0.0001837008,0.000038467493,0.000142429,0.000024912717,0.00014372567,0.00012420985,0.0010263887],"category_scores_gemma":[0.000010989815,0.00011682618,0.00012245952,0.0001670458,0.000064164335,0.00006305739,0.000017843815,0.00022679391,0.00060758437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000072088034,0.00023145296,0.00005501225,0.000009223256,0.000018990133,0.000011811759,0.00030236904,2.5089727e-7,0.88642967,0.00003583885,0.099161685,0.013671601],"study_design_scores_gemma":[0.00093274587,0.0002413661,0.004792779,0.000023076158,0.000061752595,0.000040999512,0.00010937202,0.000005054217,0.68700266,0.000102445694,0.30655593,0.00013179745],"about_ca_topic_score_codex":0.00001275623,"about_ca_topic_score_gemma":3.2164786e-7,"teacher_disagreement_score":0.20739424,"about_ca_system_score_codex":0.00006042621,"about_ca_system_score_gemma":0.00006993064,"threshold_uncertainty_score":0.9998868},"labels":[],"label_agreement":null},{"id":"W2091385166","doi":"10.4161/auto.32170","title":"A mitochondrial-associated link between an effector caspase and autophagic flux","year":2014,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; Burnaby Hospital; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Cell biology; Mitochondrion; Effector; Caspase; Programmed cell death; Apoptosis; Regulator; Caspase 2; Flux (metallurgy); Biochemistry; Chemistry; Gene","score_opus":0.013283998082704548,"score_gpt":0.2798946406102827,"score_spread":0.26661064252757816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091385166","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99546826,0.0007253311,0.00027846696,0.00059117813,0.00039249458,0.0005764624,0.00004037786,0.00045960495,0.0014677957],"genre_scores_gemma":[0.99352145,0.00002417919,0.00048441737,0.0013063289,0.0018161804,0.00005100167,0.00030447473,0.000075336386,0.0024166533],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9979371,0.00026229073,0.00037803355,0.0005709706,0.00034354615,0.00050810026],"domain_scores_gemma":[0.9982326,0.0002892703,0.0001405704,0.00063498726,0.000088158115,0.0006144401],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003064741,0.00034261835,0.000673795,0.00015601823,0.0001807714,0.00005915247,0.00015681607,0.00030110206,0.00050903653],"category_scores_gemma":[0.00029299536,0.00030158166,0.00015755737,0.0002160587,0.00013763398,0.00017785515,0.000056406905,0.00031377818,0.0003105392],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001525398,0.0020324227,0.06421447,0.0006690264,0.002941597,0.0016722581,0.0035675303,0.000016961618,0.37830538,0.0084489025,0.008778406,0.5278276],"study_design_scores_gemma":[0.011353939,0.002955681,0.8746016,0.00018894766,0.00082796084,0.000087020606,0.000027415386,0.0024792596,0.08199288,0.002947438,0.021798806,0.00073905365],"about_ca_topic_score_codex":0.00009779323,"about_ca_topic_score_gemma":0.000010120748,"teacher_disagreement_score":0.81038713,"about_ca_system_score_codex":0.000075405136,"about_ca_system_score_gemma":0.000107768064,"threshold_uncertainty_score":0.9999436},"labels":[],"label_agreement":null},{"id":"W2091533593","doi":"10.4161/auto.23568","title":"Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells","year":2013,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Eye Institute","keywords":"Autophagy; Biology; Trabecular meshwork; Cell biology; Flux (metallurgy); Biochemistry; Materials science; Apoptosis; Neuroscience; Metallurgy; Glaucoma","score_opus":0.009579818133166593,"score_gpt":0.24230947463011768,"score_spread":0.2327296564969511,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091533593","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946926,0.001660163,0.00020275298,0.00052416476,0.000099609555,0.00089712435,0.000010451473,0.00014396642,0.001769145],"genre_scores_gemma":[0.99588114,0.00013758913,0.0012572645,0.001055217,0.000092652685,0.00016223258,0.0000820213,0.00004276492,0.0012891027],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99829245,0.00011759846,0.00040525972,0.0004879736,0.00029027302,0.00040642367],"domain_scores_gemma":[0.99893147,0.00011102487,0.000115119736,0.00043639634,0.00008295883,0.00032304702],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00015189605,0.0002766903,0.00041705815,0.00020548518,0.00007863121,0.00005273457,0.00013571694,0.00017699598,0.0023296103],"category_scores_gemma":[0.000051884865,0.00024935682,0.00010262643,0.00031680355,0.00012634843,0.00025196103,0.000031227264,0.00021612973,0.00036535267],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026260802,0.001261271,0.010790435,0.00019551115,0.0002657688,0.0003245488,0.0010639011,0.000023605382,0.94506806,0.003053514,0.001970008,0.035720795],"study_design_scores_gemma":[0.0032347776,0.0001712335,0.6582506,0.00009815801,0.00007589942,0.000017906443,0.00014761527,0.0027407561,0.33261782,0.001481883,0.0009135882,0.00024980181],"about_ca_topic_score_codex":0.0002164179,"about_ca_topic_score_gemma":0.000006705822,"teacher_disagreement_score":0.6474601,"about_ca_system_score_codex":0.0000744666,"about_ca_system_score_gemma":0.00014569082,"threshold_uncertainty_score":0.9999959},"labels":[],"label_agreement":null},{"id":"W2092045059","doi":"10.4161/auto.22258","title":"NUPR1 works against the metabolic stress-induced autophagy-associated cell death in pancreatic cancer cells","year":2012,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Instituto de Salud Carlos III; National Institutes of Health; Institut National Du Cancer; Canceropôle PACA; Ligue Contre le Cancer; Institut National de la Santé et de la Recherche Médicale","keywords":"Pancreatic cancer; Autophagy; Cancer; Biology; Disease; Cancer research; Bioinformatics; Adenocarcinoma; Life expectancy; Mechanism (biology); Pancreas; Oncology; Internal medicine; Medicine; Endocrinology; Population; Apoptosis; Genetics","score_opus":0.020960029256188548,"score_gpt":0.2861984430328147,"score_spread":0.26523841377662616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092045059","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9629244,0.030718245,0.000013369895,0.00026034276,0.0008547329,0.00086499733,0.000043057837,0.00020712004,0.0041137426],"genre_scores_gemma":[0.9906428,0.0031986916,0.00008219317,0.002989629,0.0005865654,0.00028525467,0.000058658723,0.000098516655,0.0020577004],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99701655,0.00027589544,0.0005869389,0.00043824952,0.00053286087,0.0011495276],"domain_scores_gemma":[0.9982008,0.00024543633,0.00026284353,0.0007868058,0.000090254056,0.00041387868],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004889938,0.00047148057,0.0007877578,0.00019219898,0.00019391239,0.000057313355,0.0003563586,0.0003241285,0.0008367649],"category_scores_gemma":[0.00006920435,0.00033604805,0.00029151,0.0007006365,0.00008084355,0.00030206284,0.000086164255,0.0006708946,0.00025347393],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012153679,0.013698767,0.37291318,0.0005447667,0.0036741993,0.0011551839,0.018435,0.0010116571,0.48599368,0.003553079,0.0054224627,0.09238265],"study_design_scores_gemma":[0.0038215872,0.00009006481,0.6234227,0.00030665178,0.0005127242,0.0000061327287,0.00028532548,0.0011733903,0.36766574,0.00012245627,0.0021549708,0.00043828],"about_ca_topic_score_codex":0.0005141492,"about_ca_topic_score_gemma":0.000053978434,"teacher_disagreement_score":0.2505095,"about_ca_system_score_codex":0.00024855474,"about_ca_system_score_gemma":0.00030424338,"threshold_uncertainty_score":0.99990916},"labels":[],"label_agreement":null},{"id":"W2092224586","doi":"10.1007/s11515-014-1293-3","title":"Structural biology of the macroautophagy machinery","year":2014,"lang":"en","type":"article","venue":"Frontiers in Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; U.S. Public Health Service","keywords":"Autophagy; Autophagosome; Cell biology; Biology; Computational biology; Function (biology); Gene; Biochemistry","score_opus":0.007394021444190243,"score_gpt":0.27577780798616186,"score_spread":0.2683837865419716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092224586","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923551,0.002077751,0.0012451137,0.00045238234,0.0018072369,0.00017369962,0.000016499065,0.00002085486,0.0018513302],"genre_scores_gemma":[0.9969729,0.00006502385,0.0015714067,0.000981697,0.00014713203,0.0000082484585,0.000026508054,0.000010152911,0.0002169248],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9991329,0.00017569972,0.00023389066,0.00019459598,0.00003950685,0.00022346202],"domain_scores_gemma":[0.99946386,0.000038083395,0.000090724854,0.0003412611,0.000022449181,0.00004361235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001361477,0.000112813126,0.000345609,0.00009432383,0.000031664527,0.0000013172938,0.00019560613,0.00016967692,0.0000987606],"category_scores_gemma":[0.00008564196,0.00006678832,0.00010788243,0.00014147788,0.00035928778,0.000013795681,0.00005403617,0.00017139764,0.000003675313],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020044186,0.00003620278,0.93348056,0.000023013663,0.00008497604,0.000002178824,0.000093699346,0.0000055343526,0.014168947,0.01101636,0.0016485689,0.039239496],"study_design_scores_gemma":[0.0029517042,0.00042594864,0.86863774,0.000032008695,0.000054800326,0.000031904863,0.00005008515,0.0026821312,0.022837808,0.083042406,0.019072654,0.00018079847],"about_ca_topic_score_codex":0.000047531077,"about_ca_topic_score_gemma":0.0000042895635,"teacher_disagreement_score":0.072026044,"about_ca_system_score_codex":0.00002940778,"about_ca_system_score_gemma":0.000040304665,"threshold_uncertainty_score":0.27235487},"labels":[],"label_agreement":null},{"id":"W2092269740","doi":"10.1074/mcp.m114.042168","title":"KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and Lysosome-Mediated Degradation*","year":2015,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; Princess Margaret Cancer Centre; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Ubiquitin; Ubiquitin ligase; Endosome; Lysosome; Cell biology; Ubiquitin-conjugating enzyme; Biology; Ubiquitin-Protein Ligases; Autophagy; Biochemistry; Chemistry; Intracellular; Gene","score_opus":0.022698184238410156,"score_gpt":0.25439802888058616,"score_spread":0.231699844642176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092269740","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97032505,0.0018388805,0.02323723,0.001705936,0.00023202485,0.0021456212,0.000067564026,0.00020436844,0.0002433253],"genre_scores_gemma":[0.98756963,0.00004243665,0.00788383,0.0030626277,0.00028279252,0.00020908442,0.0003705941,0.00014523425,0.00043375694],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972472,0.00021735964,0.00056397286,0.00074168853,0.00057194766,0.0006577898],"domain_scores_gemma":[0.99764985,0.000040960604,0.00020660096,0.0006618275,0.00027983266,0.0011609101],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005783325,0.0004898303,0.00062389113,0.00030961097,0.00017597698,0.00008942921,0.00022032089,0.0004910628,0.000048410402],"category_scores_gemma":[0.00030023942,0.0004868597,0.00018541713,0.00036497865,0.00011082263,0.0001438095,0.00015783793,0.0007322809,0.00014754354],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00063869986,0.00027338343,0.0006241915,0.00010528665,0.00028171233,0.0010329788,0.0018321624,0.000074871874,0.9921824,0.00023243827,0.00024170207,0.0024801835],"study_design_scores_gemma":[0.004593352,0.0007720747,0.0008251501,0.00015281416,0.00013642423,0.00006057443,0.00046669046,0.0026342575,0.98675126,0.0015453201,0.0014826817,0.00057940424],"about_ca_topic_score_codex":0.00004247949,"about_ca_topic_score_gemma":0.0000025110041,"teacher_disagreement_score":0.017244594,"about_ca_system_score_codex":0.00022147309,"about_ca_system_score_gemma":0.00042858795,"threshold_uncertainty_score":0.9997583},"labels":[],"label_agreement":null},{"id":"W2092295090","doi":"10.1038/onc.2011.168","title":"Association and dissociation of autophagy, apoptosis and necrosis by systematic chemical study","year":2011,"lang":"en","type":"article","venue":"Oncogene","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":156,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Cancer Research; Fondation Bettencourt Schueller; Institut National Du Cancer","keywords":"Autophagy; Programmed cell death; Apoptosis; Biology; Necrosis; Cell biology; Cytotoxic T cell; Inducer; Tumor necrosis factor alpha; Phenotype; Cancer research; Immunology; Biochemistry; In vitro; Genetics; Gene","score_opus":0.01457354756056478,"score_gpt":0.25534547109254757,"score_spread":0.2407719235319828,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092295090","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99782306,0.0010890849,0.0000137843645,0.000043283926,0.000033211687,0.0005097742,0.00001445513,0.000024878027,0.0004484923],"genre_scores_gemma":[0.9992407,0.00010890565,0.000108497035,0.000055982655,0.000022466673,0.0000419488,0.000011804599,0.00001143833,0.0003982613],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992579,0.000054068252,0.00024246084,0.00014459372,0.00019897312,0.000101991296],"domain_scores_gemma":[0.9994911,0.000058368387,0.0001918057,0.00011906881,0.00005995343,0.00007968997],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024445058,0.00008856896,0.00033142508,0.00003169591,0.000031510794,0.000007192885,0.000029205923,0.00007837357,0.00004235092],"category_scores_gemma":[0.000103668805,0.00007473535,0.000038187583,0.00007851045,0.000019717476,0.000047251273,0.00001970742,0.000045394572,0.0000029221308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022748587,0.0023810575,0.31752196,0.0029745563,0.0015640547,0.000004589267,0.007924471,2.4623368e-8,0.6644446,0.00008366973,0.0006793877,0.0021941366],"study_design_scores_gemma":[0.0033729805,0.00068678363,0.109933764,0.00050465635,0.0017144384,0.0000046856153,0.0010813603,0.000082150895,0.8820653,0.00035082354,0.000017872148,0.0001851911],"about_ca_topic_score_codex":0.0000668169,"about_ca_topic_score_gemma":9.936729e-7,"teacher_disagreement_score":0.21762069,"about_ca_system_score_codex":0.00007001023,"about_ca_system_score_gemma":0.000016619255,"threshold_uncertainty_score":0.3047619},"labels":[],"label_agreement":null},{"id":"W2092566326","doi":"10.1038/sj.cdd.4401936","title":"Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy","year":2006,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":607,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Institute of Genetics; University of California, San Diego; National Institutes of Health; National Heart, Lung, and Blood Institute; Tobacco-Related Disease Research Program; American Heart Association","keywords":"Autophagy; Cell biology; Programmed cell death; ATG5; Mitochondrion; Downregulation and upregulation; Apoptosis; Myocyte; Chemistry; Biology; Biochemistry; Gene","score_opus":0.006946188139793733,"score_gpt":0.2371633449888061,"score_spread":0.23021715684901237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092566326","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968731,0.0011917232,0.00038416794,0.00022415855,0.000106221494,0.00025954525,0.000010659854,0.00006210723,0.0008883496],"genre_scores_gemma":[0.99728507,0.0001585027,0.00019327576,0.00056477654,0.00018169143,0.00001765309,0.000080497455,0.000015329315,0.001503199],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992345,0.000048390968,0.00016040847,0.0002486144,0.00014672967,0.00016136612],"domain_scores_gemma":[0.9995502,0.000042977506,0.000041925217,0.00015639982,0.0000371753,0.00017131711],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010329364,0.00013664378,0.00017838003,0.0001076198,0.00010232163,0.00003691655,0.00002548589,0.00009727812,0.000063173924],"category_scores_gemma":[0.000024579767,0.00011631631,0.00004723375,0.00007329174,0.000023096889,0.00006766887,0.00003580664,0.00007027469,0.0000145345675],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002427555,0.00016254188,0.040925004,0.00005280075,0.00001826604,0.000012723282,0.00023693936,0.0000011060383,0.9500414,0.00024779222,0.0013563845,0.004517489],"study_design_scores_gemma":[0.001509023,0.00026879407,0.55872726,0.000029706065,0.0000810963,0.0000052769255,0.000027905988,0.00027636465,0.43657705,0.00059525477,0.0017713779,0.00013085056],"about_ca_topic_score_codex":0.000033477118,"about_ca_topic_score_gemma":0.0000013306686,"teacher_disagreement_score":0.5178023,"about_ca_system_score_codex":0.000024322297,"about_ca_system_score_gemma":0.000034562432,"threshold_uncertainty_score":0.47432414},"labels":[],"label_agreement":null},{"id":"W2093295909","doi":"10.1038/cddis.2015.36","title":"Autophagy is a regulator of TGF-β1-induced fibrogenesis in primary human atrial myofibroblasts","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":214,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital; University of Manitoba; Children's Hospital Research Institute of Manitoba; Research Manitoba","funders":"Canadian Institutes of Health Research; University of Manitoba; Research Manitoba; University of Calgary; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Myofibroblast; Regulator; Transforming growth factor; Cell biology; Cancer research; Fibrosis; Biology; Chemistry; Medicine; Pathology; Biochemistry; Apoptosis; Gene","score_opus":0.028453738019335133,"score_gpt":0.2791710123957052,"score_spread":0.25071727437637004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093295909","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924842,0.00512829,0.0000060152797,0.00011627165,0.000081883416,0.00041141556,0.000041398547,0.000050681196,0.0016798563],"genre_scores_gemma":[0.9981052,0.000055348435,0.000118087744,0.00059852184,0.00022181786,0.000014230958,0.000059005182,0.00002892542,0.0007988065],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99871194,0.000050810017,0.00033185535,0.00034083935,0.0002970862,0.00026749136],"domain_scores_gemma":[0.9981729,0.000026966898,0.00009715057,0.00040087666,0.00006986745,0.0012322436],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011618234,0.00020189148,0.00038895875,0.00014561525,0.00004259348,0.0000132076875,0.00008432184,0.00009911366,0.00012503777],"category_scores_gemma":[0.0000483043,0.00018057637,0.00019401663,0.00015629259,0.000059415204,0.00008629264,0.000054829605,0.000074528696,0.000018501818],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.032073718,0.004820289,0.6538185,0.004477544,0.0005748765,0.0028728812,0.004160086,0.000045229466,0.26739162,0.0023946215,0.014462099,0.012908533],"study_design_scores_gemma":[0.024782646,0.0011449676,0.884177,0.00034063534,0.00067885336,0.000013833252,0.00016076752,0.0003797477,0.08023408,0.006377043,0.0011253513,0.00058507436],"about_ca_topic_score_codex":0.00004597467,"about_ca_topic_score_gemma":7.7378735e-7,"teacher_disagreement_score":0.2303585,"about_ca_system_score_codex":0.00006203962,"about_ca_system_score_gemma":0.0006104113,"threshold_uncertainty_score":0.7363691},"labels":[],"label_agreement":null},{"id":"W2093500494","doi":"10.1038/onc.2012.252","title":"Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells","year":2012,"lang":"en","type":"article","venue":"Oncogene","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":376,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Institut National Du Cancer; Sun Yat-sen University; National Natural Science Foundation of China; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Autophagy; Biology; Cancer stem cell; Progenitor cell; Cancer research; Population; Stem cell; Side population; Carcinogenesis; Cancer cell; Cancer; Cell biology; Apoptosis; Medicine; Genetics","score_opus":0.0320378069892153,"score_gpt":0.312903518316931,"score_spread":0.28086571132771565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093500494","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9770762,0.020372124,0.00013292623,0.00055765634,0.0006761543,0.0006913942,0.00039975994,0.000032332755,0.00006149308],"genre_scores_gemma":[0.9960611,0.00067916606,0.00020825406,0.0005375673,0.0010692808,0.00013796339,0.000008161944,0.000031266925,0.0012672235],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990676,0.000030567066,0.00024482605,0.00017364293,0.00018647299,0.00029687906],"domain_scores_gemma":[0.9991104,0.00010176629,0.00016686227,0.00031706598,0.00011275122,0.0001911809],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022243218,0.00014902808,0.0003105511,0.00003106626,0.00010116693,0.000006817659,0.00009782654,0.00007925561,0.0002001058],"category_scores_gemma":[0.0000069549933,0.00009743889,0.00013986415,0.00009830788,0.0001220354,0.00006965513,0.00003337559,0.000069735615,0.000008909628],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025106592,0.0011418627,0.0558991,0.00061473437,0.0013252422,0.00002161383,0.0012635813,0.000008718231,0.85329384,0.00034630785,0.0066490094,0.07692534],"study_design_scores_gemma":[0.0031110875,0.00018611827,0.12702686,0.00011011576,0.0007580768,0.00007394025,0.00038093326,0.00022479783,0.8499286,0.000062609724,0.01791947,0.00021738894],"about_ca_topic_score_codex":0.000080906284,"about_ca_topic_score_gemma":0.000010332337,"teacher_disagreement_score":0.07670795,"about_ca_system_score_codex":0.000052399126,"about_ca_system_score_gemma":0.00011919865,"threshold_uncertainty_score":0.39734426},"labels":[],"label_agreement":null},{"id":"W2093818907","doi":"10.3390/ijerph120202289","title":"Impact of Air Pollutants on Oxidative Stress in Common Autophagy-Mediated Aging Diseases","year":2015,"lang":"en","type":"review","venue":"International Journal of Environmental Research and Public Health","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Fondation CHU de Québec; Université Laval","keywords":"Autophagy; Oxidative stress; Amyotrophic lateral sclerosis; Cell biology; Oxidative phosphorylation; Frontotemporal dementia; Disease; Biology; Dementia; Medicine; Biochemistry; Pathology; Apoptosis","score_opus":0.12226210004196776,"score_gpt":0.49315538820497173,"score_spread":0.370893288163004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093818907","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15332675,0.84317607,0.0000014058,0.0004995811,0.0001045148,0.00042589538,0.0023716774,0.0000036322374,0.000090474554],"genre_scores_gemma":[0.35771322,0.64181244,0.000006235985,0.000064110296,0.00016412226,0.00000529351,0.00018289893,0.000019224108,0.000032480883],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99597067,0.000645481,0.0009657827,0.00021581087,0.001770714,0.00043152386],"domain_scores_gemma":[0.9974794,0.000503718,0.0007049181,0.0001806294,0.0001217495,0.0010095824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013889133,0.00023259725,0.0012198213,0.0012872405,0.00004183809,0.00003158104,0.00037750922,0.000115549105,0.0002851009],"category_scores_gemma":[0.00025664095,0.00016091178,0.00029867343,0.00023640029,0.00026884433,0.00019850793,0.00012357403,0.00093097717,0.000011474983],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040638793,0.0034169145,0.008025197,0.000713225,0.000920185,0.0005394705,0.00022359092,0.0000014607045,0.000006660975,0.000037052516,0.00026470676,0.98544514],"study_design_scores_gemma":[0.015414149,0.025922546,0.64092803,0.055608958,0.00023681278,0.0015093476,0.0016455449,0.00008783479,0.000037999835,0.0016634819,0.2560438,0.0009014701],"about_ca_topic_score_codex":0.00009796997,"about_ca_topic_score_gemma":0.0000060177267,"teacher_disagreement_score":0.9845437,"about_ca_system_score_codex":0.002136554,"about_ca_system_score_gemma":0.0032035206,"threshold_uncertainty_score":0.6561792},"labels":[],"label_agreement":null},{"id":"W2094624168","doi":"10.4161/15548627.2014.978221","title":"Autophagy facilitates secretion and protects against degeneration of the Harderian gland","year":2014,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SKiN Health","funders":"","keywords":"Harderian gland; Lipid droplet; Biology; Endoplasmic reticulum; Cell biology; Autophagy; Secretion; Perilipin; Vacuole; Lamellar granule; Biochemistry; Cytoplasm; Endocrinology; Adipocyte; Adipose tissue; Apoptosis","score_opus":0.007697311358611444,"score_gpt":0.22589557497065219,"score_spread":0.21819826361204075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094624168","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956425,0.0007859245,0.0006359776,0.00045812552,0.00018160343,0.0005743461,0.000012080484,0.00006807703,0.0016413707],"genre_scores_gemma":[0.9979056,0.00006504495,0.00029244425,0.00068171223,0.00014137535,0.000043161363,0.000029398538,0.000018122884,0.0008231405],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899143,0.0001165125,0.0002494172,0.00023756223,0.0002241946,0.00018088659],"domain_scores_gemma":[0.99930584,0.00004733121,0.00011299003,0.0003578105,0.00007934611,0.00009668574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021670289,0.00015218213,0.00024695194,0.000054567146,0.0001276134,0.000018558136,0.00008364675,0.00010473647,0.00007631301],"category_scores_gemma":[0.00013489006,0.00010354031,0.000089212386,0.00012987143,0.000138001,0.00007922465,0.000037437163,0.000115094546,0.000013444012],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029337153,0.00023869304,0.0051405746,0.00043282393,0.00017296913,0.000012001702,0.0017473907,0.00006454358,0.91870564,0.008163679,0.00046786264,0.064560436],"study_design_scores_gemma":[0.0025290314,0.00036648865,0.25458074,0.00012660756,0.00006762056,0.000026615216,0.000057814097,0.006557026,0.72366744,0.0025250239,0.009314532,0.00018103588],"about_ca_topic_score_codex":0.000026076576,"about_ca_topic_score_gemma":0.0000078396515,"teacher_disagreement_score":0.24944016,"about_ca_system_score_codex":0.000023909104,"about_ca_system_score_gemma":0.000072806346,"threshold_uncertainty_score":0.42222512},"labels":[],"label_agreement":null},{"id":"W2095304974","doi":"10.1016/j.chom.2009.10.003","title":"Eating Twice for the Sake of Immunity: A Phagocytic Receptor that Activates Autophagy","year":2009,"lang":"en","type":"review","venue":"Cell Host & Microbe","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Autophagy; Biology; Inducer; Cell biology; Immunity; Mechanism (biology); Receptor; Phagocytosis; Immunology; Immune system; Genetics; Gene; Apoptosis","score_opus":0.05322531197777822,"score_gpt":0.3455503873870503,"score_spread":0.2923250754092721,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095304974","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011551183,0.9945005,0.000078614845,0.000047026213,0.00033631167,0.0027035247,0.00016456711,0.00008000181,0.0009342989],"genre_scores_gemma":[0.0006165328,0.9935462,0.00061610405,0.00043647958,0.000406483,0.00018869412,0.00037492352,0.00013687412,0.003677725],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99798137,0.00015266721,0.0007137815,0.00044741886,0.00021759354,0.0004871769],"domain_scores_gemma":[0.9968068,0.0011061945,0.00079729053,0.0010342883,0.00012345484,0.00013198695],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036799666,0.0006143285,0.0020202568,0.00015988458,0.00022129164,0.000038066257,0.0005636613,0.00039278626,0.0004370567],"category_scores_gemma":[0.00008847854,0.00039471235,0.0012216764,0.00032754283,0.00015444274,0.00006540273,0.000095252544,0.00062379177,0.000086095046],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016495486,0.00045952786,0.0000029812932,0.023466276,0.00084532914,0.000013918767,0.0004356268,1.9766729e-7,0.01209219,0.00002283655,0.0032346277,0.95926154],"study_design_scores_gemma":[0.0011662794,0.00035708843,0.000019264808,0.0124363275,0.0027792589,0.000040984523,0.00013771479,0.0000052275605,0.03435053,0.000015692096,0.94835055,0.00034105955],"about_ca_topic_score_codex":0.000033937675,"about_ca_topic_score_gemma":7.570092e-7,"teacher_disagreement_score":0.9589205,"about_ca_system_score_codex":0.00018432582,"about_ca_system_score_gemma":0.00065272534,"threshold_uncertainty_score":0.99985045},"labels":[],"label_agreement":null},{"id":"W2095308362","doi":"10.1016/j.virol.2010.03.026","title":"Viral interactions with macroautophagy: A double-edged sword","year":2010,"lang":"en","type":"review","venue":"Virology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Innate immune system; Cell biology; Viral replication; Programmed cell death; Viral pathogenesis; Virus; Mechanism (biology); Virology; Immunity; Bystander effect; Immune system; Immunology; Genetics; Apoptosis","score_opus":0.03948754335065453,"score_gpt":0.38017547332401386,"score_spread":0.34068792997335934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095308362","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014824844,0.98958653,0.000057028665,0.00016494592,0.00081666885,0.0010290032,0.000032010157,0.00018154708,0.0066497927],"genre_scores_gemma":[0.00030297486,0.99106455,0.00025167473,0.0007635766,0.0008840831,0.00041184534,0.0002908201,0.000119012424,0.0059114574],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99832684,0.00010486078,0.00045710802,0.00053549337,0.00015518855,0.00042049965],"domain_scores_gemma":[0.99852955,0.00011115278,0.0002850331,0.00079078565,0.000053092066,0.00023037106],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000104817984,0.00048846164,0.0018858815,0.00031031642,0.00010075803,0.00001955758,0.00022842518,0.00060268794,0.0017791083],"category_scores_gemma":[0.000012713276,0.00032425937,0.00048172896,0.00022673229,0.00023729568,0.000059089503,0.00006167996,0.0015676945,0.0009675782],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007543173,0.0003973022,0.000006421905,0.0022942894,0.0009368814,0.0011367141,0.000044713535,8.243024e-8,0.000055494453,0.0012174468,0.0009230505,0.9922333],"study_design_scores_gemma":[0.0020814578,0.00046077798,0.00006612061,0.0012410163,0.0021770305,0.0024147332,0.0000029099276,0.0000026743614,0.000020218557,0.0000933871,0.9911665,0.0002731884],"about_ca_topic_score_codex":0.000016083726,"about_ca_topic_score_gemma":0.000025352865,"teacher_disagreement_score":0.9919601,"about_ca_system_score_codex":0.00006488121,"about_ca_system_score_gemma":0.00046194805,"threshold_uncertainty_score":0.99992096},"labels":[],"label_agreement":null},{"id":"W2096300340","doi":"10.1093/abbs/gms010","title":"Interplay between the cellular autophagy machinery and positive-stranded RNA viruses","year":2012,"lang":"en","type":"review","venue":"Acta Biochimica et Biophysica Sinica","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; St. Paul's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Cell biology; Innate immune system; Regulator; RNA; Viral replication; Genome; Immune system; Immunity; Virus; Virology; Genetics; Gene","score_opus":0.051086909722024905,"score_gpt":0.37417509040215946,"score_spread":0.32308818068013456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096300340","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03129666,0.96364653,0.000011379715,0.00082769187,0.0003002774,0.0015207948,0.0008311119,0.00018265223,0.0013828997],"genre_scores_gemma":[0.17951472,0.8164149,0.00008519247,0.0013524514,0.0013328844,0.000072869305,0.00075913046,0.00016927962,0.000298568],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966322,0.00042745995,0.0010090669,0.0008457365,0.00041878072,0.0006667086],"domain_scores_gemma":[0.9965503,0.00096468243,0.00066311343,0.0013047203,0.000059650913,0.00045751547],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038855345,0.0009989836,0.002603726,0.00019559839,0.00023463031,0.00011315113,0.00062582805,0.00057943445,0.00013172593],"category_scores_gemma":[0.000054246666,0.00059493334,0.0011995045,0.00038784058,0.00059555314,0.00016483192,0.000319374,0.0012592443,0.00018158257],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003238109,0.0013121886,0.000012788435,0.0062967525,0.006269583,0.00011458745,0.0005435808,1.3379816e-8,0.012635679,0.00091041136,0.0014225891,0.97015804],"study_design_scores_gemma":[0.0014482358,0.0006222856,0.0011253494,0.0075043635,0.013476275,0.000099185636,0.00001356097,0.0000031800869,0.013821554,0.0003680596,0.9602619,0.0012560559],"about_ca_topic_score_codex":0.000029773058,"about_ca_topic_score_gemma":7.716665e-7,"teacher_disagreement_score":0.96890193,"about_ca_system_score_codex":0.0000710563,"about_ca_system_score_gemma":0.00032374612,"threshold_uncertainty_score":0.9996502},"labels":[],"label_agreement":null},{"id":"W2096494569","doi":"10.1242/jcs.114819","title":"NBR1 acts as an autophagy receptor for peroxisomes","year":2012,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":354,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Cell biology; Peroxisome; Ubiquitin; Receptor; Biochemistry; Gene; Apoptosis","score_opus":0.021014810603012937,"score_gpt":0.3434615917899661,"score_spread":0.3224467811869532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096494569","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939375,0.0011385215,0.0002451856,0.00036545354,0.00079117494,0.00012977661,0.0000015637404,0.000010545559,0.0033802714],"genre_scores_gemma":[0.99200875,0.00011280025,0.004919145,0.0008020145,0.00078877213,0.000002053591,6.6721776e-7,0.000009398258,0.001356385],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998812,0.000018383695,0.00023530649,0.000100018806,0.0004977313,0.00033654753],"domain_scores_gemma":[0.9986958,0.000054532153,0.00021531657,0.00016385589,0.00025229566,0.00061820523],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010050297,0.000083461375,0.00018836242,0.00014156528,0.00013311375,0.000032618133,0.00024755968,0.000038860628,0.00040837456],"category_scores_gemma":[0.00016580988,0.000057337817,0.000111786074,0.00022094767,0.00018265254,0.0008690947,0.000016644119,0.00011286245,0.000044479304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038193798,0.0007255284,0.0014965612,0.000032637894,0.0000182581,0.000012754693,0.0014235079,0.0000023812424,0.9852041,0.0011299558,0.0015405116,0.008031867],"study_design_scores_gemma":[0.0015363267,0.001434442,0.01870981,0.000042059986,0.000055584627,0.00016314762,0.00034104462,0.000074026015,0.9318623,0.00060257333,0.04507613,0.00010256337],"about_ca_topic_score_codex":9.243253e-7,"about_ca_topic_score_gemma":6.661422e-8,"teacher_disagreement_score":0.05334181,"about_ca_system_score_codex":0.00007292361,"about_ca_system_score_gemma":0.0005021875,"threshold_uncertainty_score":0.44714153},"labels":[],"label_agreement":null},{"id":"W2097066287","doi":"10.1007/s10549-007-9873-4","title":"Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization","year":2008,"lang":"en","type":"article","venue":"Breast Cancer Research and Treatment","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":271,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Tamoxifen; Autophagy; Cancer research; ATG5; Gene knockdown; Breast cancer; Antiestrogen; Biology; Estrogen receptor; Programmed cell death; Viability assay; Cancer cell; Cancer; Apoptosis; Medicine; Internal medicine","score_opus":0.030837105704221483,"score_gpt":0.3310155380438172,"score_spread":0.30017843233959574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097066287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989291,0.006715167,0.000024968675,0.0018858095,0.00013420002,0.00076352723,0.0009633574,0.000056607514,0.0001653554],"genre_scores_gemma":[0.9743198,0.023203734,0.00011936818,0.0001293544,0.0007203699,0.00033985244,0.00007140766,0.00003317306,0.0010629433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981353,0.00010535635,0.00022390299,0.0005135647,0.0005178707,0.00050396967],"domain_scores_gemma":[0.9989783,0.000060166956,0.00006138131,0.00021683745,0.00025412062,0.00042919742],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007535085,0.0002506179,0.00033777856,0.00017127178,0.00049783423,0.000057707628,0.000035024095,0.00010732109,0.0003857515],"category_scores_gemma":[0.0000033727952,0.00018837108,0.00006631149,0.00025359323,0.00041554333,0.0001575696,0.000040048846,0.00015174008,0.000010387991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011473902,0.0013852696,0.013003924,0.0001835602,0.0007441184,0.0015852612,0.001229934,0.0000071758927,0.8789818,0.0002306195,0.0006721996,0.09050218],"study_design_scores_gemma":[0.009990189,0.0011471641,0.46672803,0.00042325398,0.00018765022,0.0016755573,0.00017358096,0.00018177083,0.51802605,0.00024437843,0.00086806976,0.00035433285],"about_ca_topic_score_codex":0.0051043886,"about_ca_topic_score_gemma":0.00051317044,"teacher_disagreement_score":0.45372412,"about_ca_system_score_codex":0.00035048614,"about_ca_system_score_gemma":0.00047887056,"threshold_uncertainty_score":0.7716342},"labels":[],"label_agreement":null},{"id":"W2097821680","doi":"10.7554/elife.03706","title":"Autophagy is a critical regulator of memory CD8+ T cell formation","year":2014,"lang":"en","type":"article","venue":"eLife","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":362,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Natural Sciences and Engineering Research Council of Canada; Wellcome Trust; Lady Tata Memorial Trust; Allan and Nesta Ferguson Charitable Trust; Cancer Research UK; Medical Research Council; Wellcome","keywords":"Autophagy; Cell biology; CD8; Biology; Cytotoxic T cell; T cell; Memory cell; Immune system; Immunology; Genetics; Apoptosis","score_opus":0.010176624105292737,"score_gpt":0.28153606824085525,"score_spread":0.2713594441355625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097821680","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9779601,0.00065232866,0.0023892475,0.000978476,0.00013923184,0.0001525588,0.000007833542,0.00007026693,0.017649932],"genre_scores_gemma":[0.99447805,0.000024377,0.00083814666,0.0033994098,0.0002358637,0.0000073293736,0.000009017252,0.00001310841,0.0009947113],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99924123,0.000029954403,0.00021283569,0.00010920233,0.00026948613,0.00013729166],"domain_scores_gemma":[0.9993924,0.000058251215,0.000047723297,0.000273639,0.00009890671,0.00012907742],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014210196,0.000078870726,0.00018634961,0.000050151397,0.00003215695,0.0000046944165,0.000054056178,0.000068020505,0.00066694216],"category_scores_gemma":[0.000099902136,0.00006733967,0.00008901805,0.00006595058,0.000059240276,0.000081008846,0.000014778372,0.00006818092,0.00017010269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017465682,0.0031916793,0.0033471582,0.0038663803,0.0003129206,0.00010704771,0.008455437,0.000029356996,0.63789076,0.04741528,0.22971737,0.06392002],"study_design_scores_gemma":[0.0014849016,0.000266334,0.010336583,0.00006906296,0.00007509058,0.000013458589,0.00009759805,0.004468047,0.96945524,0.0006563289,0.012979807,0.00009754479],"about_ca_topic_score_codex":0.000004498538,"about_ca_topic_score_gemma":1.8249068e-7,"teacher_disagreement_score":0.33156446,"about_ca_system_score_codex":0.000016580278,"about_ca_system_score_gemma":0.00004420272,"threshold_uncertainty_score":0.7302549},"labels":[],"label_agreement":null},{"id":"W2097830998","doi":"10.1038/cr.2013.166","title":"Autophagy regulation by nutrient signaling","year":2013,"lang":"en","type":"review","venue":"Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":707,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Autophagy; mTORC1; Cell biology; Biology; Crosstalk; Nutrient sensing; Kinase; AMPK; Catabolism; Anabolism; Homeostasis; Protein kinase A; Signal transduction; Intracellular; Biochemistry; Metabolism; PI3K/AKT/mTOR pathway; Apoptosis","score_opus":0.17865716572756685,"score_gpt":0.46782485095294213,"score_spread":0.2891676852253753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097830998","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00012933448,0.9869586,0.000052770054,0.000031492847,0.00011691911,0.0022000591,0.000019534129,0.00006981007,0.0104214335],"genre_scores_gemma":[0.00012389895,0.9457823,0.000083697094,0.00003185086,0.00046360784,0.00041756927,0.00053493294,0.00009677651,0.05246539],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99672663,0.00045412022,0.00051268,0.00055986794,0.0011008244,0.0006458546],"domain_scores_gemma":[0.9979566,0.00041390964,0.00013713422,0.00076344603,0.0003164047,0.0004125546],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00093004544,0.00030977456,0.0010853284,0.0004190123,0.0001794464,0.0000774196,0.00030035173,0.00045898664,0.0044998503],"category_scores_gemma":[0.00007046637,0.00023282056,0.00041398898,0.0006528898,0.0001484333,0.000061091065,0.000109670116,0.0010701222,0.0035502017],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018501392,0.00029010331,3.9293366e-7,0.016202217,0.000110713954,0.000056651654,0.000039593855,1.1428845e-7,0.00051064196,0.00018976806,0.08638763,0.8961937],"study_design_scores_gemma":[0.0004050087,0.00016663634,9.856645e-7,0.004824738,0.00018933942,0.000011251203,0.0000149550215,0.000021353108,0.0034018431,0.00031934577,0.99045956,0.000184985],"about_ca_topic_score_codex":0.0000202822,"about_ca_topic_score_gemma":5.264825e-8,"teacher_disagreement_score":0.9040719,"about_ca_system_score_codex":0.0003403198,"about_ca_system_score_gemma":0.00077748793,"threshold_uncertainty_score":0.99722564},"labels":[],"label_agreement":null},{"id":"W2098766444","doi":"10.1042/bj20140312","title":"Autophagy is required and protects against apoptosis during myoblast differentiation","year":2014,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"BECN1; Autophagy; C2C12; Cell biology; Myogenesis; Cellular differentiation; Sequestosome 1; Programmed cell death; Biology; Apoptosis; Myocyte; Molecular biology; Chemistry; Biochemistry","score_opus":0.00766848701806194,"score_gpt":0.23711147291266407,"score_spread":0.22944298589460213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098766444","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980611,0.00040341043,0.00036362823,0.00063201133,0.000091178656,0.00014239868,0.000002271175,0.000044082313,0.00025987372],"genre_scores_gemma":[0.99798316,0.00018911582,0.00032017106,0.0006828981,0.00063894,0.000008021987,0.000006497271,0.000019080248,0.00015210987],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909043,0.000033345685,0.00023070766,0.00018245053,0.00024185127,0.0002212084],"domain_scores_gemma":[0.99936825,0.000017650198,0.000106877866,0.00014448893,0.00006160004,0.00030114088],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000095017866,0.00013423208,0.00020128976,0.00007170675,0.0001317693,0.000047187372,0.000063164436,0.00011373555,0.000106447624],"category_scores_gemma":[0.00008532054,0.00010636568,0.000097764845,0.00007352216,0.00005670398,0.00006995517,0.000032132306,0.00023628926,0.000015369234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020033798,0.00009535563,0.0007980116,0.00006522189,0.00007735044,0.000007278486,0.0001145639,1.5542662e-7,0.9931964,0.00002036829,0.00058897096,0.004835953],"study_design_scores_gemma":[0.0021609291,0.00011447516,0.03918676,0.00017561231,0.000043513348,0.00012285361,0.000016682887,0.00029116255,0.9571383,0.00033759617,0.00029337782,0.00011873443],"about_ca_topic_score_codex":6.994588e-7,"about_ca_topic_score_gemma":2.3654398e-8,"teacher_disagreement_score":0.03838875,"about_ca_system_score_codex":0.000049666076,"about_ca_system_score_gemma":0.00003087151,"threshold_uncertainty_score":0.43374664},"labels":[],"label_agreement":null},{"id":"W2099277984","doi":"10.1371/journal.pgen.1005006","title":"Regulators of Autophagosome Formation in Drosophila Muscles","year":2015,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Autophagy; Biology; Autophagosome; Cell biology; ATG5; Gene knockdown; Skeletal muscle; Proteasome; Myocyte; Biochemistry; Gene; Anatomy","score_opus":0.045354458584937626,"score_gpt":0.282357274647717,"score_spread":0.23700281606277934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099277984","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969751,0.0015768884,0.000018743722,0.00016465993,0.000055896657,0.00019456218,0.0000047666967,0.000027114269,0.0009822604],"genre_scores_gemma":[0.9990162,0.000090593174,0.000559314,0.00015008637,0.000079930964,0.000008102626,0.000015413874,0.000013555778,0.000066791115],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993193,0.00001953801,0.00022801546,0.000087665874,0.00023094713,0.000114527844],"domain_scores_gemma":[0.99952275,0.000011099849,0.00006457526,0.00021583324,0.00007688601,0.00010883844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006246725,0.000074010495,0.00016716491,0.00009887083,0.000008765036,0.0000033172369,0.00005611371,0.000063378946,0.000023471164],"category_scores_gemma":[0.00003086149,0.000067458146,0.000038421425,0.00013987288,0.000039508595,0.000044747914,0.00001804124,0.000054288503,0.000018600578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012542794,0.004494864,0.11537011,0.00132109,0.00042389953,0.00037238814,0.016287519,0.001531683,0.81882155,0.005000308,0.0021200306,0.033002306],"study_design_scores_gemma":[0.0028071813,0.00038691098,0.059360188,0.00013327424,0.0000759715,0.000018794814,0.0002421986,0.009615439,0.91757756,0.009033194,0.00061524764,0.00013402186],"about_ca_topic_score_codex":0.0000017013098,"about_ca_topic_score_gemma":0.0000016463397,"teacher_disagreement_score":0.09875605,"about_ca_system_score_codex":0.00003969338,"about_ca_system_score_gemma":0.000062305546,"threshold_uncertainty_score":0.27508634},"labels":[],"label_agreement":null},{"id":"W2099390343","doi":"10.7150/jca.7030","title":"The Autophagy Inhibitor Verteporfin Moderately Enhances the Antitumor Activity of Gemcitabine in a Pancreatic Ductal Adenocarcinoma Model","year":2013,"lang":"en","type":"article","venue":"Journal of Cancer","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":107,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency; Centre for Drug Research and Development; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Verteporfin; Gemcitabine; Cancer research; Medicine; Oncology; Chemotherapy; Pharmacology; Chemistry; Internal medicine; Apoptosis; Surgery","score_opus":0.01530685019496001,"score_gpt":0.2932295492842753,"score_spread":0.2779226990893153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099390343","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9797048,0.017176697,0.00015982243,0.0022442988,0.00023789854,0.00028670733,0.0000043337805,0.0000050447516,0.00018042045],"genre_scores_gemma":[0.9965112,0.0024220457,0.000074187046,0.00025359882,0.00033668068,0.00003547498,2.7762488e-7,0.000015616442,0.0003509013],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987208,0.00007174805,0.0004713757,0.000106283165,0.00041073607,0.0002190201],"domain_scores_gemma":[0.9988889,0.00013652923,0.00043627954,0.00019341677,0.00025019873,0.00009468826],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028450903,0.00013724333,0.00039808845,0.00007299396,0.00008215367,0.000029510318,0.00016824764,0.000052891493,0.00011670274],"category_scores_gemma":[0.00007772432,0.000067078465,0.00015994003,0.00016774226,0.0001509878,0.0002544265,0.000023947525,0.00031511267,0.000003641507],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0067183794,0.0012594629,0.074307024,0.00038124764,0.0017523643,0.0004224093,0.002891138,0.004048869,0.8792411,0.00075962505,0.005566907,0.022651466],"study_design_scores_gemma":[0.0027003107,0.0004087351,0.7197553,0.00039184577,0.00025242547,0.00013935994,0.00020346214,0.041979678,0.23184754,0.0021070866,0.000082644954,0.00013161103],"about_ca_topic_score_codex":0.00022790278,"about_ca_topic_score_gemma":0.00007020075,"teacher_disagreement_score":0.6473936,"about_ca_system_score_codex":0.00009893808,"about_ca_system_score_gemma":0.00080430094,"threshold_uncertainty_score":0.27353802},"labels":[],"label_agreement":null},{"id":"W2099818615","doi":"10.1016/j.bbamcr.2010.10.010","title":"Anti-apoptosis and cell survival: A review","year":2010,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":651,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Military College of Canada","funders":"Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada; Association de Recherche sur la Polyarthrite","keywords":"Programmed cell death; Autophagy; Apoptosis; Cell biology; Biology; Cell survival; Cell type; Cell; Genetics","score_opus":0.0735575199106936,"score_gpt":0.4171047949505487,"score_spread":0.3435472750398551,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099818615","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.017074907,0.9696426,0.000004896158,0.0008161451,0.00020762304,0.003847042,0.00015963272,0.00012724425,0.008119915],"genre_scores_gemma":[0.0040078424,0.99175763,0.00023614097,0.0007511282,0.0003422326,0.00041546914,0.0007687579,0.00037970697,0.001341081],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99222606,0.0016264298,0.0010620091,0.0017885574,0.0019447656,0.0013521896],"domain_scores_gemma":[0.9949571,0.0005290076,0.00046944065,0.0025699646,0.00047460807,0.0009998911],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0017651796,0.0011464849,0.0036622775,0.0007095896,0.00027684798,0.00019410838,0.0010670425,0.0009904564,0.00022513724],"category_scores_gemma":[0.0001931047,0.0009163602,0.0015270049,0.001695683,0.0006956122,0.000100915124,0.00074328855,0.0036368854,0.00052002387],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010741014,0.0024990786,3.0129848e-7,0.23799309,0.0010181665,0.00055924954,0.00010099592,1.3535714e-8,0.50937724,0.00021780215,0.01082617,0.23730046],"study_design_scores_gemma":[0.0007566425,0.00041048913,0.0000056948065,0.024468442,0.0021101788,0.000027057682,0.0000112152,0.0000020352022,0.2021597,0.000054048247,0.769149,0.0008454946],"about_ca_topic_score_codex":0.00003719102,"about_ca_topic_score_gemma":4.822098e-7,"teacher_disagreement_score":0.75832283,"about_ca_system_score_codex":0.00012461733,"about_ca_system_score_gemma":0.0016610303,"threshold_uncertainty_score":0.9993287},"labels":[],"label_agreement":null},{"id":"W2100153355","doi":"10.1161/hypertensionaha.113.01028","title":"p53 Mediates Autophagy and Cell Death by a Mechanism Contingent On Bnip3","year":2013,"lang":"en","type":"article","venue":"Hypertension","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Autophagy; Programmed cell death; Cell biology; Biology; Mitochondrion; Cell; Apoptosis; Genetics","score_opus":0.014271559380605592,"score_gpt":0.2208341633245888,"score_spread":0.2065626039439832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2100153355","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944419,0.0024682654,0.000036605095,0.00082228734,0.00015453558,0.00040354804,0.000004917516,0.000101980884,0.0015659482],"genre_scores_gemma":[0.9907981,0.0006459621,0.00025809143,0.006640316,0.00009922114,0.000032967895,0.000031466043,0.000028801944,0.0014650802],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911034,0.000026384789,0.0001533245,0.0002692904,0.00021330817,0.00022735287],"domain_scores_gemma":[0.99936354,0.000059035647,0.00004877546,0.00022555722,0.0000750514,0.00022805612],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006488629,0.00016233127,0.00026144038,0.000052392505,0.000079465965,0.000019742802,0.000043322976,0.00010506515,0.00036708376],"category_scores_gemma":[0.000028418548,0.00011612047,0.000056282483,0.00004557252,0.000026396703,0.000055086708,0.000028058135,0.000115697614,0.00033828043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000107796914,0.00047350762,0.0005071547,0.00004837817,0.00005496263,0.00011950383,0.00017034769,2.4035924e-7,0.9586656,0.000577403,0.032451257,0.006823834],"study_design_scores_gemma":[0.0054075187,0.00130505,0.025157204,0.0001798087,0.0002155308,0.00012664124,0.000219942,0.0040788185,0.9506627,0.0031762316,0.009093975,0.00037658657],"about_ca_topic_score_codex":0.000084078885,"about_ca_topic_score_gemma":3.7368815e-7,"teacher_disagreement_score":0.024650048,"about_ca_system_score_codex":0.000018011466,"about_ca_system_score_gemma":0.00002145721,"threshold_uncertainty_score":0.47352555},"labels":[],"label_agreement":null},{"id":"W2100388369","doi":"10.1038/nature10546","title":"Image-based genome-wide siRNA screen identifies selective autophagy factors","year":2011,"lang":"en","type":"article","venue":"Nature","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":480,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Autophagy; Mitophagy; Biology; Cell biology; Genetic screen; Vacuole; Parkin; BAG3; Sindbis virus; RNA interference; Gene; RNA; Genetics; Cytoplasm; Phenotype","score_opus":0.014558932854610719,"score_gpt":0.2697116759002308,"score_spread":0.2551527430456201,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2100388369","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9820404,0.00277451,0.00024586674,0.0002171261,0.00027475983,0.00040206854,0.00005298339,0.00025784766,0.013734421],"genre_scores_gemma":[0.993864,0.000027269241,0.0009774355,0.0031352746,0.00017874315,0.0000134206575,0.00012869328,0.000044534027,0.0016306053],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99880075,0.00004341303,0.00018233371,0.00033353726,0.00032535603,0.00031460891],"domain_scores_gemma":[0.99906015,0.00006781335,0.00008667965,0.0003800581,0.00020740295,0.00019788496],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000094299205,0.00023160252,0.000294678,0.00015836168,0.00011071877,0.000021801156,0.00017899416,0.0007782208,0.0014967575],"category_scores_gemma":[0.00013701347,0.00018194414,0.00020397679,0.0002784383,0.00010296066,0.00014101545,0.00002580886,0.0014044129,0.00012920467],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0082346415,0.0050169765,0.5260351,0.00093830697,0.0053526154,0.0044449507,0.017316688,0.000010329183,0.33344668,0.0028126633,0.090443425,0.0059476546],"study_design_scores_gemma":[0.0011983297,0.00017358793,0.75586164,0.00003225706,0.00013723687,0.0000058157216,0.000117284566,0.000031160045,0.23891453,0.0008450478,0.002494613,0.00018847341],"about_ca_topic_score_codex":0.000056052406,"about_ca_topic_score_gemma":0.0000092636465,"teacher_disagreement_score":0.2298266,"about_ca_system_score_codex":0.00007940728,"about_ca_system_score_gemma":0.00017687988,"threshold_uncertainty_score":0.999416},"labels":[],"label_agreement":null},{"id":"W2101275022","doi":"10.1158/1538-7445.am2014-315","title":"Abstract 315: Regulation of the transcription factor TFEB and the autophagic/lysosomal network by GSK3 in pancreatic cancer cells","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Autophagy; TFEB; PI3K/AKT/mTOR pathway; Programmed cell death; Pancreatic cancer; Cell biology; Cancer research; Apoptosis; Transcription factor; Chemistry; Cancer cell; Biology; Small hairpin RNA; Signal transduction; Cancer; Biochemistry; Gene knockdown; Gene","score_opus":0.03381195289388746,"score_gpt":0.34638440333527964,"score_spread":0.3125724504413922,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101275022","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876602,0.0087317135,0.000018790155,0.0020471753,0.00015824856,0.0007470101,0.000025556701,0.000011447664,0.00059981213],"genre_scores_gemma":[0.99616116,0.0022248656,0.0000066085354,0.00021615,0.00030067848,0.00017054533,0.000005105415,0.000018281575,0.0008965911],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9984481,0.00029054476,0.00023770095,0.00020889562,0.00049971533,0.00031507396],"domain_scores_gemma":[0.99918205,0.00024800806,0.00006949382,0.00031755678,0.00010351009,0.000079356825],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007262186,0.00010504932,0.0002474584,0.00004996784,0.00013176752,0.000020352902,0.00015116001,0.000086744825,0.00058122876],"category_scores_gemma":[0.000038061018,0.000058104182,0.00007252239,0.00032988188,0.00040476417,0.00006463507,0.000023382712,0.00036246947,0.0000036740623],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029695474,0.00016454705,0.033480737,0.00048304652,0.00019228505,0.0000029650512,0.0025971422,0.00073690206,0.91948485,0.001772161,0.0069258865,0.031189905],"study_design_scores_gemma":[0.004289815,0.00008146914,0.8676062,0.00045518987,0.00005313435,0.0000010792961,0.00009453852,0.0018541223,0.11988755,0.0021899578,0.0033885355,0.000098366014],"about_ca_topic_score_codex":0.0017497555,"about_ca_topic_score_gemma":0.00020109981,"teacher_disagreement_score":0.8341255,"about_ca_system_score_codex":0.00012123522,"about_ca_system_score_gemma":0.00017842886,"threshold_uncertainty_score":0.63640475},"labels":[],"label_agreement":null},{"id":"W2101299068","doi":"10.1186/s12943-015-0449-3","title":"Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine","year":2015,"lang":"en","type":"article","venue":"Molecular Cancer","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":186,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Centre National de la Recherche Scientifique","keywords":"Autophagy; Gemcitabine; Pancreatic cancer; Biology; Blockade; Stem cell; Cancer research; Cancer stem cell; Cancer; Internal medicine; Oncology; Apoptosis; Pharmacology; Cell biology; Medicine; Receptor; Biochemistry; Genetics","score_opus":0.01020384848871452,"score_gpt":0.2767204830298783,"score_spread":0.26651663454116375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101299068","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95862174,0.040146288,0.000050704057,0.00034987874,0.00012738878,0.00040004004,0.000024839768,0.00001879719,0.00026033746],"genre_scores_gemma":[0.998875,0.0004827288,0.000023543016,0.00009488447,0.000072413124,0.00009844541,0.0000022751044,0.00002448021,0.000326186],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901444,0.00012193965,0.00018005488,0.00019905096,0.0003032909,0.00018123284],"domain_scores_gemma":[0.99930406,0.000049453778,0.00016365174,0.00026664985,0.00009540938,0.00012077701],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017536296,0.00016528473,0.0004249819,0.000048559203,0.000029160206,0.0000062276617,0.00009354313,0.00005716407,0.000050878567],"category_scores_gemma":[0.000013810681,0.000102982536,0.000107257656,0.00017124739,0.0001743802,0.00003965898,0.000040653205,0.00011019366,0.0000010775692],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00075894804,0.000100620724,0.005712325,0.00036107184,0.0003737449,0.000050441187,0.00039196733,0.00011365439,0.9820743,0.000011747515,0.00014045827,0.0099106915],"study_design_scores_gemma":[0.0019888056,0.00045396126,0.027845008,0.00012817113,0.0006683254,0.000007379976,0.000045764667,0.00031798327,0.9683307,0.00003613361,0.00008664744,0.00009115799],"about_ca_topic_score_codex":0.00086545973,"about_ca_topic_score_gemma":0.0000069492808,"teacher_disagreement_score":0.04025332,"about_ca_system_score_codex":0.000058146707,"about_ca_system_score_gemma":0.00020603003,"threshold_uncertainty_score":0.41995057},"labels":[],"label_agreement":null},{"id":"W2102785604","doi":"10.1093/toxsci/kfp101","title":"Oxidative Stress Induces Parallel Autophagy and Mitochondria Dysfunction in Human Glioma U251 Cells","year":2009,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":212,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China; University of Manitoba","keywords":"Autophagy; PI3K/AKT/mTOR pathway; Cell biology; Protein kinase B; Programmed cell death; Reactive oxygen species; Apoptosis; Mitochondrion; Oxidative stress; Biology; Chemistry; Signal transduction; Biochemistry","score_opus":0.03593977144721425,"score_gpt":0.32669118224351806,"score_spread":0.29075141079630384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2102785604","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99424285,0.00041590809,0.00003244524,0.000841952,0.00009815227,0.00031387206,0.0000026635257,0.000061826395,0.003990341],"genre_scores_gemma":[0.99818546,0.000046621208,0.00053031184,0.00092413486,0.00009363568,0.000015862399,0.000003276588,0.0000024065173,0.00019832225],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987614,0.00008109433,0.0002058541,0.00038532595,0.00027113137,0.0002951971],"domain_scores_gemma":[0.99957746,0.00007703029,0.000068693706,0.00009947166,0.000020963324,0.0001563989],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022969909,0.00013574224,0.00023909731,0.00012043712,0.00020310123,0.00004984223,0.00013911433,0.00013217349,0.00043770808],"category_scores_gemma":[0.00004727483,0.000087976936,0.000041481853,0.00042867678,0.00041879094,0.00016642633,0.000028370516,0.00015524028,0.000013406319],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001195156,0.0007205757,0.0027007032,0.0000064814094,0.000009922861,0.00016230904,0.0002655731,0.00003636142,0.98496646,0.003655648,0.00018422246,0.0071722586],"study_design_scores_gemma":[0.0015519542,0.0037748516,0.6365629,0.00004551895,0.000021906273,0.000016928756,0.00039822902,0.0002136946,0.34467566,0.012414472,0.00013391551,0.00018997886],"about_ca_topic_score_codex":0.000018960684,"about_ca_topic_score_gemma":0.0000108132435,"teacher_disagreement_score":0.64029074,"about_ca_system_score_codex":0.000036583304,"about_ca_system_score_gemma":0.000043462995,"threshold_uncertainty_score":0.47925964},"labels":[],"label_agreement":null},{"id":"W2103341611","doi":"10.7150/ijbs.8337","title":"Involvement of PAR-4 in Cannabinoid-Dependent Sensitization of Osteosarcoma Cells to TRAIL-Induced Apoptosis","year":2014,"lang":"en","type":"article","venue":"International Journal of Biological Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"European Regional Development Fund; Ministero dell’Istruzione, dell’Università e della Ricerca","keywords":"Cell biology; Apoptosis; Cannabinoid receptor; Autophagy; Programmed cell death; Chemistry; Autophagosome; Cannabinoid; Cell; Cell cycle; Cancer research; Biology; Receptor; Agonist; Biochemistry","score_opus":0.03925578792697735,"score_gpt":0.3199376431452621,"score_spread":0.2806818552182847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103341611","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965445,0.000039457216,0.00031283783,0.0024043208,0.00026337602,0.00008465839,0.000004203708,0.0000019966064,0.00034465286],"genre_scores_gemma":[0.9987167,0.000043884476,0.0006344765,0.00048929494,0.000099252764,0.0000012743994,0.0000013905616,0.0000015741937,0.000012157601],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876666,0.00007829295,0.0004611267,0.00010447128,0.00049248745,0.000096933094],"domain_scores_gemma":[0.9992041,0.00009340489,0.00028992555,0.000046559588,0.00028115412,0.00008485187],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006955596,0.00006220806,0.00021229508,0.00019285067,0.0000145695285,0.000007764274,0.0002358423,0.00004333847,0.00008280207],"category_scores_gemma":[0.00018080889,0.000038253584,0.000082498955,0.00016538313,0.000107395426,0.000055263336,0.00003367187,0.00006169622,0.0000018830866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002613184,0.0003252787,0.05778665,0.0000064530163,0.000043780514,0.0000086455375,0.00031459384,0.0001863175,0.92896426,0.0008772965,0.00003503139,0.011190368],"study_design_scores_gemma":[0.0007698687,0.001549234,0.15835762,0.00011904115,0.000009450471,0.000012791134,0.00018384548,0.00015650793,0.83732295,0.0013832826,0.00008604252,0.000049355334],"about_ca_topic_score_codex":0.000082974264,"about_ca_topic_score_gemma":0.000017296783,"teacher_disagreement_score":0.10057097,"about_ca_system_score_codex":0.00004234292,"about_ca_system_score_gemma":0.00007457349,"threshold_uncertainty_score":0.15599358},"labels":[],"label_agreement":null},{"id":"W2104765365","doi":"10.3389/fonc.2012.00078","title":"The non-death role of metacaspase proteases","year":2012,"lang":"en","type":"article","venue":"Frontiers in Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; Muscular Dystrophy Association","keywords":"Proteases; Programmed cell death; Caspase; Protease; Cell biology; Biology; Apoptosis; Function (biology); Cell; Enzyme; Genetics; Biochemistry","score_opus":0.011536647934787796,"score_gpt":0.30797823898879867,"score_spread":0.29644159105401086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2104765365","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9552395,0.023439134,0.0005304592,0.0006824184,0.0010329235,0.0007607969,0.0000062222425,0.000021681373,0.018286902],"genre_scores_gemma":[0.9947339,0.00047291265,0.0033864407,0.00036942115,0.00022368097,0.00011591218,0.000004999875,0.000012435248,0.00068025925],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992308,0.000083774496,0.00020472132,0.00009338077,0.00010721313,0.00028012192],"domain_scores_gemma":[0.9994612,0.00007588712,0.000088670815,0.00023387896,0.00002987611,0.0001105025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030366983,0.00008418663,0.0002938174,0.00007207873,0.00004486074,0.0000019886497,0.00010055555,0.00009970564,0.000055397973],"category_scores_gemma":[0.00009163249,0.000054317356,0.000079476864,0.0001069875,0.00012654588,0.000051049657,0.000025573707,0.00014073357,0.0000119346305],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001891051,0.001664423,0.7863078,0.0000475131,0.00043298435,0.0000641148,0.0017446886,0.0000031084576,0.0037745123,0.0025291452,0.03258049,0.16896017],"study_design_scores_gemma":[0.0042389594,0.0012064213,0.33817002,0.000048822727,0.00028505558,0.000057423887,0.0031532042,0.00037393344,0.036521778,0.0069618016,0.60879093,0.00019164853],"about_ca_topic_score_codex":0.000029951489,"about_ca_topic_score_gemma":0.0000026693742,"teacher_disagreement_score":0.57621044,"about_ca_system_score_codex":0.00009726955,"about_ca_system_score_gemma":0.00016162464,"threshold_uncertainty_score":0.22149974},"labels":[],"label_agreement":null},{"id":"W2105409495","doi":"10.1038/ni.1823","title":"Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry","year":2009,"lang":"en","type":"article","venue":"Nature Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1270,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"ATG16L1; Autophagy; NOD2; Cell biology; NOD1; Biology; Intracellular; Chemistry; Innate immune system; Immunology; Genetics; Immune system","score_opus":0.004469011109758072,"score_gpt":0.25346945280779043,"score_spread":0.24900044169803237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2105409495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96906257,0.020496579,0.0000014393287,0.0070839077,0.0005555882,0.00041520153,0.000053408312,0.000045253706,0.0022860784],"genre_scores_gemma":[0.99277323,0.0008012769,0.000043506585,0.00400137,0.00028980337,0.0000140301845,0.00006988722,0.000016696154,0.0019902012],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989248,0.00012730963,0.00024186599,0.0002580918,0.0001607911,0.0002871224],"domain_scores_gemma":[0.9991002,0.00021368181,0.00011681888,0.0004507646,0.000060624017,0.00005792416],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002109843,0.00017696386,0.00033953675,0.000054873115,0.0001665432,0.000012905756,0.00015934724,0.00037365186,0.00039474017],"category_scores_gemma":[0.00018244714,0.000098971235,0.00009054384,0.00017562062,0.0001512661,0.00003688608,0.00008170081,0.00056369376,0.00003512523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020700074,0.000093743394,0.00012395238,0.000014165616,0.0002365744,0.00002516237,0.0010025242,0.000001323945,0.95996886,0.00021137303,0.008081529,0.02817077],"study_design_scores_gemma":[0.002482931,0.00054106186,0.030383924,0.00007921406,0.00013846954,0.00019366489,0.0000979034,0.000025392375,0.7267098,0.000048972863,0.23914771,0.00015100354],"about_ca_topic_score_codex":0.00001609723,"about_ca_topic_score_gemma":0.000012207508,"teacher_disagreement_score":0.23325911,"about_ca_system_score_codex":0.000044013657,"about_ca_system_score_gemma":0.00004431838,"threshold_uncertainty_score":0.43221283},"labels":[],"label_agreement":null},{"id":"W2105504231","doi":"10.1139/y10-010","title":"Methods for detecting autophagy and determining autophagy-induced cell deathThis review is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease.","year":2010,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":107,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autophagy; Programmed cell death; Cell biology; Intracellular; Oxidative stress; Biology; Cell; Disease; Medicine; Apoptosis; Pathology; Biochemistry","score_opus":0.04762255980553187,"score_gpt":0.41249589806278253,"score_spread":0.36487333825725066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2105504231","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.056603227,0.9414515,0.000003949308,0.00026245054,0.00045428294,0.0011114221,0.00007059516,0.000002240429,0.00004032879],"genre_scores_gemma":[0.012614712,0.9843104,0.0007325352,0.0014106926,0.0008138797,0.000050638686,0.000017938695,0.000029511564,0.000019717887],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99733496,0.00086573727,0.0010607159,0.0003321851,0.00006229477,0.00034412934],"domain_scores_gemma":[0.99707156,0.0007008883,0.0012500021,0.000100837744,0.00012455063,0.0007521568],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009407919,0.00028748674,0.0023563744,0.00072719366,0.000071215516,0.000005184386,0.000112019574,0.00031921788,0.0010720146],"category_scores_gemma":[0.00034897026,0.00024975935,0.0001818116,0.00027085637,0.00018446038,0.00007365088,0.00001748917,0.0009140399,1.397148e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044691478,0.00014476808,0.00010696589,0.053959966,0.0003155246,0.000053712036,0.0008085267,4.6432237e-7,0.016048523,0.000015744681,0.00021208622,0.9278868],"study_design_scores_gemma":[0.019436136,0.016145037,0.00646596,0.12445366,0.007355054,0.0007000142,0.00036055024,0.00028549586,0.12507094,0.0019350172,0.6961527,0.0016394639],"about_ca_topic_score_codex":0.00020929375,"about_ca_topic_score_gemma":0.00027731844,"teacher_disagreement_score":0.92624736,"about_ca_system_score_codex":0.00011988706,"about_ca_system_score_gemma":0.0032669671,"threshold_uncertainty_score":0.99999547},"labels":[],"label_agreement":null},{"id":"W2105516896","doi":"10.1093/carcin/bgu049","title":"Combination of AKT inhibition with autophagy blockade effectively reduces ascites-derived ovarian cancer cell viability","year":2014,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Protein kinase B; PI3K/AKT/mTOR pathway; Viability assay; Cancer research; Cancer cell; Cell growth; Biology; Downregulation and upregulation; Chemistry; Cell; Signal transduction; Pharmacology; Cell biology; Cancer; Apoptosis; Biochemistry","score_opus":0.009238823520365253,"score_gpt":0.2445169041405713,"score_spread":0.23527808062020605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2105516896","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964303,0.0008905308,0.00056355895,0.00018174681,0.000104032835,0.00060464867,0.000022560906,0.00007756901,0.001125057],"genre_scores_gemma":[0.9991255,0.00004749475,0.00024403719,0.00017187567,0.00012655143,0.00011783402,0.000038831855,0.00003242608,0.00009548331],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987292,0.00016858923,0.0002454,0.00035081213,0.00029735925,0.00020861745],"domain_scores_gemma":[0.99897796,0.000107564454,0.00016895606,0.00033244328,0.00027321719,0.00013988449],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024222456,0.00019457191,0.00038812894,0.00008087429,0.000086200154,0.000009330079,0.000065714084,0.00010805691,0.0002204303],"category_scores_gemma":[0.000044295262,0.0001575749,0.00011947025,0.00023589171,0.00014227726,0.00009981453,0.000019975241,0.000076144024,0.0000063587127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005918524,0.0004939246,0.035204504,0.00029848536,0.00011269648,0.000007867274,0.0004155452,0.000034510424,0.95571774,0.00013991032,0.000032396147,0.0069505805],"study_design_scores_gemma":[0.0020454195,0.00042599568,0.3986182,0.000066046545,0.00017990265,0.000003833619,0.000039836228,0.00021421767,0.59813005,0.00014951287,0.00002887355,0.00009811407],"about_ca_topic_score_codex":0.00043225774,"about_ca_topic_score_gemma":0.000019866353,"teacher_disagreement_score":0.36341366,"about_ca_system_score_codex":0.00014531845,"about_ca_system_score_gemma":0.00015213221,"threshold_uncertainty_score":0.6425718},"labels":[],"label_agreement":null},{"id":"W2106031420","doi":"10.1242/jcs.080341","title":"Identification of PTPσ as an autophagic phosphatase","year":2011,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Cancer Institute","keywords":"Autophagy; Biology; Cell biology; Phosphatase; Protein tyrosine phosphatase; Phosphatidylinositol; Lysosome; Effector; BAG3; Kinase; Phosphorylation; Biochemistry; Enzyme","score_opus":0.02200672044176576,"score_gpt":0.3033609892157166,"score_spread":0.2813542687739508,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106031420","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99590474,0.0007056213,0.00023620743,0.000035754318,0.00022746639,0.000059140668,0.0000014750186,0.0000050406566,0.0028245638],"genre_scores_gemma":[0.9987142,0.000102223596,0.0006797031,0.0001479686,0.000054551758,3.9450708e-7,3.8762292e-7,0.000003939466,0.0002966408],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989296,0.000016400376,0.00035631898,0.00009635425,0.00048463134,0.000116695475],"domain_scores_gemma":[0.998822,0.000010452905,0.00043028157,0.000216503,0.00029926078,0.00022154443],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008128945,0.000052693733,0.0001340775,0.0001428921,0.00005218283,0.000011992951,0.00027298043,0.000022361815,0.00041468226],"category_scores_gemma":[0.000061257655,0.00003853898,0.000063085536,0.00030779655,0.00025901344,0.00046823322,0.000013897307,0.000082639126,0.000028833107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002525529,0.0007469271,0.0013985952,0.00002607163,0.000011860176,0.00010259614,0.0015483017,0.0000028496324,0.9897016,0.001468861,0.00011698726,0.0046227775],"study_design_scores_gemma":[0.0005142762,0.0005360721,0.05150567,0.000023484752,0.000040755796,0.00007183264,0.0001617143,0.00011640378,0.94472283,0.002132044,0.00013781356,0.000037107602],"about_ca_topic_score_codex":0.00000840355,"about_ca_topic_score_gemma":1.5698384e-7,"teacher_disagreement_score":0.050107077,"about_ca_system_score_codex":0.000027660259,"about_ca_system_score_gemma":0.0004030696,"threshold_uncertainty_score":0.454048},"labels":[],"label_agreement":null},{"id":"W2106195012","doi":"10.4049/jimmunol.0900441","title":"The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":568,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; Toronto Rehabilitation Institute; University of Toronto","funders":"","keywords":"Autophagy; Signal transducing adaptor protein; Cell biology; Ubiquitin; Biology; Intracellular parasite; BAG3; Innate immune system; Cytosol; Intracellular; Signal transduction; Biochemistry; Receptor; Gene","score_opus":0.011812578158065757,"score_gpt":0.25496414602002704,"score_spread":0.2431515678619613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106195012","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9545228,0.01102822,0.00019880483,0.032718137,0.00051550096,0.0004945466,0.0000029502414,0.000020922565,0.0004981457],"genre_scores_gemma":[0.99412215,0.00053260714,0.0001617025,0.0034719459,0.0005649874,0.000008517483,9.878861e-7,0.000017315851,0.0011198078],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984242,0.00038719032,0.0004905247,0.00009271258,0.00024211602,0.00036325675],"domain_scores_gemma":[0.9986413,0.00021202824,0.00035753226,0.0005265609,0.00016894739,0.00009359042],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012254516,0.00016724985,0.0003145485,0.00007093268,0.00041493686,0.00003193004,0.00065685075,0.00008756415,0.00014631175],"category_scores_gemma":[0.00025633007,0.000067158864,0.00016141482,0.00017401927,0.00014875835,0.0000809398,0.000057952824,0.00057047384,0.0000750649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035953885,0.00016956916,0.000022115024,0.0000046316227,0.00053077145,0.00011580194,0.0020086768,0.000011482786,0.94426405,0.0024343524,0.0032341261,0.043609027],"study_design_scores_gemma":[0.0040571513,0.006765126,0.117946476,0.00032719987,0.00030572605,0.0028054654,0.0018041686,0.00006381994,0.63089377,0.007618063,0.22709046,0.00032256125],"about_ca_topic_score_codex":0.000009172746,"about_ca_topic_score_gemma":0.0000034543903,"teacher_disagreement_score":0.3133703,"about_ca_system_score_codex":0.000077671124,"about_ca_system_score_gemma":0.0002319409,"threshold_uncertainty_score":0.31914008},"labels":[],"label_agreement":null},{"id":"W2106476697","doi":"10.1038/ncomms3189","title":"Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress","year":2013,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":158,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health; Boston Area Diabetes Endocrinology Research Center","keywords":"Autophagy; ROCK1; Cell biology; Regulator; BAG3; Kinase; Protein kinase A; Biology; Autophagosome; Chemistry; Apoptosis; Biochemistry; Gene","score_opus":0.011546991500558752,"score_gpt":0.33154755679611136,"score_spread":0.3200005652955526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106476697","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9741659,0.021916118,0.000028039383,0.00263539,0.0000894349,0.0004840718,0.00009211937,0.00007143876,0.00051747705],"genre_scores_gemma":[0.99740577,0.00096129964,0.00086245936,0.00018880094,0.000045475263,0.00010486311,0.00016901632,0.000022673823,0.00023963886],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986946,0.00012592835,0.00056381227,0.00017114478,0.00028716162,0.00015734443],"domain_scores_gemma":[0.99656516,0.00034581838,0.0002256241,0.0020516054,0.0006704104,0.00014137798],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013665523,0.0001264571,0.00033036683,0.00017690197,0.000118617994,0.000012464734,0.00053717324,0.0002687525,0.0002682352],"category_scores_gemma":[0.0010023874,0.000116647156,0.00014417055,0.00040113038,0.00028229435,0.0001562553,0.00014007407,0.00049818103,0.000057845707],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013317037,0.0024243894,0.009731495,0.00035930792,0.00044881098,0.0000053205213,0.0009392578,0.000008265658,0.9147817,0.06878814,0.0006398542,0.0017403136],"study_design_scores_gemma":[0.00095530046,0.000050723767,0.53917766,0.00013824637,0.0002505359,0.000010926769,0.00023253902,0.0010865242,0.4557363,0.0014135145,0.0008257076,0.00012200914],"about_ca_topic_score_codex":0.00006364477,"about_ca_topic_score_gemma":0.000012038181,"teacher_disagreement_score":0.5294462,"about_ca_system_score_codex":0.000024714544,"about_ca_system_score_gemma":0.0001274615,"threshold_uncertainty_score":0.47567332},"labels":[],"label_agreement":null},{"id":"W2106972520","doi":"10.1016/j.ccr.2008.06.004","title":"A Molecule Targeting VHL-Deficient Renal Cell Carcinoma that Induces Autophagy","year":2008,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":254,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; Silicon Valley Community Foundation","keywords":"Autophagy; Cancer research; Renal cell carcinoma; Biology; Medicine; Cell biology; Internal medicine; Apoptosis; Genetics","score_opus":0.02690341651448548,"score_gpt":0.26250946115061813,"score_spread":0.23560604463613266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106972520","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9466587,0.028630631,0.000055214827,0.000106098545,0.00031677567,0.00026099515,0.000018884677,0.00009160889,0.023861133],"genre_scores_gemma":[0.9920857,0.00092327263,0.00018669463,0.001255667,0.00038255457,0.00006439853,0.000031121785,0.000043956174,0.005026619],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986168,0.00003445695,0.00021495624,0.00038073957,0.00033610995,0.00041689866],"domain_scores_gemma":[0.99923694,0.000022488408,0.00011403131,0.00030993044,0.00006761349,0.00024898854],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006793342,0.0002191007,0.00028126335,0.0000531457,0.00017213039,0.000011643151,0.00013934741,0.00010874453,0.0014974959],"category_scores_gemma":[0.000005405457,0.00018799011,0.00015488076,0.00015109351,0.00008870492,0.00007794448,0.00004278925,0.00020554857,0.00009738646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003708311,0.0008611611,0.013834912,0.00029695712,0.000070347705,0.0015308799,0.0058328193,0.00012842225,0.948683,0.000037402122,0.026879054,0.001474194],"study_design_scores_gemma":[0.0018481029,0.00017574735,0.016218003,0.000034120963,0.00007190582,0.000023484134,0.0003523896,0.00018243774,0.9719195,0.0000135561,0.008932039,0.00022871677],"about_ca_topic_score_codex":0.0003183938,"about_ca_topic_score_gemma":0.000003517504,"teacher_disagreement_score":0.045427058,"about_ca_system_score_codex":0.00017823714,"about_ca_system_score_gemma":0.000359665,"threshold_uncertainty_score":0.9994153},"labels":[],"label_agreement":null},{"id":"W2107429225","doi":"10.1002/iub.334","title":"Trafficking and signaling in mammalian autophagy","year":2010,"lang":"en","type":"review","venue":"IUBMB Life","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Tellabs (Canada)","funders":"","keywords":"Autophagy; Cell biology; Endosome; Organelle; Cytosol; Lysosome; Biology; Homeostasis; Chemistry; Biochemistry; Intracellular; Apoptosis; Enzyme","score_opus":0.04543079805161661,"score_gpt":0.3530546887894295,"score_spread":0.30762389073781293,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2107429225","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0044104247,0.9936624,0.000004893414,0.00004845879,0.00029126994,0.0006513012,0.0000142727995,0.000086257016,0.0008307148],"genre_scores_gemma":[0.0022541077,0.99567914,0.00018169943,0.0004390465,0.00076688704,0.00007226297,0.00006156932,0.00008476154,0.00046053808],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99838716,0.00008131207,0.00056397874,0.00042177175,0.00020930781,0.00033645914],"domain_scores_gemma":[0.9989746,0.0001279107,0.0001842122,0.0003550802,0.000022807491,0.00033535075],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027289582,0.0003705842,0.0015257187,0.00027453218,0.000047449408,0.000034581637,0.00013097854,0.00051910407,0.00028769166],"category_scores_gemma":[0.00010640443,0.00029915676,0.0002889455,0.00023638153,0.0000710347,0.000049107446,0.00003760823,0.00085218373,0.00007452143],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014013225,0.00007629793,0.000024290599,0.0065075555,0.000088978806,0.00039165316,0.00010704109,2.2713134e-7,0.00000828445,0.0001824091,0.00010382773,0.9924954],"study_design_scores_gemma":[0.0006857704,0.00005325152,0.00013935045,0.008434794,0.00053409865,0.00012979697,0.00001599023,0.000010050477,0.000016823553,0.000039157185,0.98965126,0.00028963707],"about_ca_topic_score_codex":0.000014440983,"about_ca_topic_score_gemma":0.00000557702,"teacher_disagreement_score":0.9922058,"about_ca_system_score_codex":0.000049669692,"about_ca_system_score_gemma":0.00050524116,"threshold_uncertainty_score":0.99994606},"labels":[],"label_agreement":null},{"id":"W2108900682","doi":"10.15252/embj.201592237","title":"A Ubl/ubiquitin switch in the activation of Parkin","year":2015,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":219,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill Genome Centre; McGill University","funders":"Canada Research Chairs; Canadian Institutes of Health Research; Parkinson Society Canada","keywords":"Biology; Parkin; Ubiquitin; Ubiquitin-Protein Ligases; Genetics; Cell biology; Ubiquitin ligase; Ubiquitins; Computational biology; Gene; Internal medicine","score_opus":0.057118776667457107,"score_gpt":0.32795430742856263,"score_spread":0.2708355307611055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108900682","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883139,0.00040665804,0.00014030955,0.005998721,0.000078613215,0.00011931171,5.4511304e-7,0.0000049310947,0.0049370057],"genre_scores_gemma":[0.9980663,0.000048510476,0.0000360101,0.0013428823,0.00036433633,0.000004041304,0.000001202461,0.0000062139893,0.00013051616],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9992291,0.00013934197,0.00018296654,0.00004315048,0.0002960409,0.00010942421],"domain_scores_gemma":[0.99952316,0.00007775268,0.00011084083,0.00016377516,0.00006868972,0.000055798013],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010731319,0.000054478012,0.000110359295,0.00004509293,0.000044079137,0.000013751271,0.00014722423,0.000023412102,0.000101952646],"category_scores_gemma":[0.000098292716,0.000024905914,0.00005335352,0.0001356364,0.000038597143,0.000057578254,0.000010412717,0.0002684111,0.000011508015],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.017099358,0.006064579,0.12066037,0.00023856206,0.0019530089,0.0016331701,0.23063114,0.0009572783,0.11884456,0.03117086,0.21134497,0.25940213],"study_design_scores_gemma":[0.021537442,0.0024513402,0.5825268,0.0010924633,0.00053989975,0.005044224,0.035468537,0.0017151905,0.14441217,0.1530018,0.051724657,0.00048546641],"about_ca_topic_score_codex":0.000017498107,"about_ca_topic_score_gemma":0.0000019273991,"teacher_disagreement_score":0.46186644,"about_ca_system_score_codex":0.00003108663,"about_ca_system_score_gemma":0.00014823598,"threshold_uncertainty_score":0.11661276},"labels":[],"label_agreement":null},{"id":"W2109826292","doi":"10.1091/mbc.e07-09-0892","title":"Arp2 Links Autophagic Machinery with the Actin Cytoskeleton","year":2008,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":120,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Université de Genève; Medical School, University of Michigan; National Institutes of Health; Brandeis University; Yale University","keywords":"Cell biology; Vacuole; Biology; Lysosome; Organelle; Cytoplasm; Vesicle; Autophagy; Cytosol; Transport protein; Actin cytoskeleton; Cytoskeleton; Cell; Membrane; Biochemistry","score_opus":0.00710885262568107,"score_gpt":0.24164278583616192,"score_spread":0.23453393321048085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109826292","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887966,0.0021146776,0.0007049764,0.0036622365,0.0000886107,0.00027750098,0.000004826105,0.000029567116,0.0043209842],"genre_scores_gemma":[0.99398947,0.00007442452,0.000243385,0.003492166,0.000056735655,0.00001137049,0.000011135895,0.000019910285,0.0021014174],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992402,0.00013548695,0.00013356586,0.00018332341,0.000115082876,0.00019230875],"domain_scores_gemma":[0.9991692,0.000044284898,0.00011377193,0.00058255374,0.000037858546,0.00005234256],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009882701,0.0001427343,0.00021701715,0.00003145387,0.000115558505,0.0000018162079,0.0002627007,0.00016781958,0.00007930479],"category_scores_gemma":[0.000015143766,0.00006379702,0.00017101888,0.00013142882,0.00043688953,0.000009342457,0.000060147133,0.0003686773,0.000022044838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035688488,0.00024781856,0.0067305695,0.000035555462,0.00022180151,0.0001629741,0.00026336766,0.00004952115,0.98928607,0.00039184216,0.0013502981,0.0009032829],"study_design_scores_gemma":[0.0012431439,0.00037254769,0.014410245,0.000018089882,0.00011937636,0.00015948211,0.0000231234,0.00005831416,0.9758976,0.0003728356,0.007225226,0.000100022495],"about_ca_topic_score_codex":0.000027482178,"about_ca_topic_score_gemma":0.0000012411025,"teacher_disagreement_score":0.013388491,"about_ca_system_score_codex":0.000013780475,"about_ca_system_score_gemma":0.000098398574,"threshold_uncertainty_score":0.2601567},"labels":[],"label_agreement":null},{"id":"W2109882045","doi":"10.1172/jci74985","title":"Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":620,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"National Heart, Lung, and Blood Institute; Weill Cornell Medical College; College of Veterinary Medicine, Cornell University; National Institutes of Health; Brigham and Women's Hospital","keywords":"Necroptosis; Mitophagy; PINK1; Mitochondrion; Autophagy; Programmed cell death; Cell biology; Pathogenesis; Parkin; Biology; Mitochondrial ROS; Immunology; Cancer research; Medicine; Pathology; Apoptosis; Biochemistry; Disease","score_opus":0.049808708557568145,"score_gpt":0.3692851976442535,"score_spread":0.31947648908668536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109882045","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98412734,0.00059343287,0.0029753996,0.011385098,0.00059998163,0.00018341106,0.000004243883,0.0000070502933,0.0001240545],"genre_scores_gemma":[0.99053663,0.00016055781,0.0012798742,0.007088502,0.0008034457,0.0000033916135,0.0000026340977,0.00001065986,0.00011432129],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9977638,0.00031085644,0.0013173787,0.00010478003,0.00039377695,0.00010940049],"domain_scores_gemma":[0.9972962,0.00083193945,0.0008108696,0.000243127,0.0005383811,0.00027944267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0023626548,0.00008975795,0.0005088953,0.00007733991,0.000044882676,0.000013495548,0.00015884185,0.00010955239,0.000044929293],"category_scores_gemma":[0.0036400524,0.000052805073,0.00030507406,0.00017509917,0.00014193698,0.00006464375,0.000022341723,0.00022295112,0.000020367494],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026581925,0.0009611747,0.7150268,0.00015306885,0.0012163592,0.000035768127,0.000490845,0.00039766048,0.13651389,0.004815462,0.0244873,0.11324351],"study_design_scores_gemma":[0.0026209112,0.0011476339,0.9091718,0.00024309712,0.00035663118,0.000018153332,0.000058372556,0.00030914892,0.07213631,0.0053338804,0.008534021,0.00006998591],"about_ca_topic_score_codex":0.0000065100176,"about_ca_topic_score_gemma":0.000001988292,"teacher_disagreement_score":0.19414508,"about_ca_system_score_codex":0.00001909277,"about_ca_system_score_gemma":0.00019710572,"threshold_uncertainty_score":0.43577456},"labels":[],"label_agreement":null},{"id":"W2110866976","doi":"10.1091/mbc.e09-11-0969","title":"Post-Golgi Sec Proteins Are Required for Autophagy in <i>Saccharomyces cerevisiae</i>","year":2010,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":174,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Nankai University; University of Toronto; National Institutes of Health; Louisiana State University","keywords":"Autophagy; ATG8; Biology; Cell biology; Autophagosome; Rab; Golgi apparatus; Vesicular transport protein; Autophagy-related protein 13; Cytokinesis; GTPase; Biochemistry; Vesicle; Cell; Cell division; Signal transduction; Endoplasmic reticulum; Membrane","score_opus":0.007019714001786207,"score_gpt":0.2670132625737889,"score_spread":0.2599935485720027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110866976","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99397165,0.0012963488,0.00027638217,0.002385292,0.00025737192,0.001161518,0.000056406323,0.000026817966,0.000568228],"genre_scores_gemma":[0.9959426,0.000016724112,0.0015210767,0.001769938,0.00006764771,0.000096814714,0.00002894389,0.000025196054,0.00053108914],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990615,0.00007395773,0.0002620081,0.000264813,0.000082416875,0.00025526484],"domain_scores_gemma":[0.9990638,0.00004041429,0.00018310231,0.000557446,0.00008795578,0.00006731162],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018328411,0.00015673113,0.00033316467,0.00006705587,0.000043577613,0.0000040257573,0.00029110606,0.0002226182,0.00008313287],"category_scores_gemma":[0.00010628669,0.00010607283,0.00024138618,0.0001132094,0.0001896578,0.000019518075,0.00006785326,0.00022534496,0.000009890752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018807936,0.00020378204,0.0030350096,0.00012434505,0.000043324042,0.000017502376,0.000062988314,0.0000012213332,0.99492127,0.0006794055,0.00009166202,0.0006314325],"study_design_scores_gemma":[0.0018223509,0.00028427088,0.0070801144,0.00005112298,0.00005743405,0.000014203149,0.000025385436,0.000033171164,0.98442847,0.00296822,0.00312588,0.00010936478],"about_ca_topic_score_codex":0.00003462716,"about_ca_topic_score_gemma":0.000019145795,"teacher_disagreement_score":0.010492765,"about_ca_system_score_codex":0.000013218706,"about_ca_system_score_gemma":0.00010362705,"threshold_uncertainty_score":0.43255246},"labels":[],"label_agreement":null},{"id":"W2110950722","doi":"10.1016/j.devcel.2007.12.011","title":"PpAtg30 Tags Peroxisomes for Turnover by Selective Autophagy","year":2008,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":329,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; University of California, San Diego; National Institutes of Health; Computer Modelling Group; National Institute of Diabetes and Digestive and Kidney Diseases; European Molecular Biology Organization","keywords":"Biology; Autophagy; Peroxisome; Cell biology; Computational biology; Biochemistry; Gene; Apoptosis","score_opus":0.013287332604031851,"score_gpt":0.24037756309078034,"score_spread":0.22709023048674848,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110950722","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98194474,0.0011789899,0.00026280127,0.000098275596,0.00015135821,0.00058229436,0.00005093389,0.00010789921,0.015622703],"genre_scores_gemma":[0.9715685,0.00011771259,0.003179689,0.0016717548,0.00009124948,0.00010722371,0.00021516735,0.000040993236,0.02300771],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998953,0.000012193949,0.00020404886,0.000294039,0.00021720218,0.00031953666],"domain_scores_gemma":[0.99956286,0.000042473508,0.000053830532,0.00010697455,0.000064507534,0.00016935432],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000050304563,0.00019427939,0.00024574538,0.000060622147,0.00018485486,0.0000077679115,0.00008410975,0.00009308274,0.0005317197],"category_scores_gemma":[0.000012805929,0.00017278787,0.00011193559,0.000137694,0.000070515045,0.000086586886,0.000025141735,0.0001085374,0.00019738443],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014971618,0.0021251107,0.038382005,0.00024973592,0.00055447157,0.00033276918,0.0068243085,0.0000013638293,0.37653634,0.0001501223,0.56654805,0.006798533],"study_design_scores_gemma":[0.003819673,0.00027059022,0.045436118,0.000017787654,0.00003679833,0.00014330915,0.00019252599,0.000028333598,0.8380803,0.00011799223,0.111569375,0.00028718569],"about_ca_topic_score_codex":0.000011679029,"about_ca_topic_score_gemma":0.0000010968224,"teacher_disagreement_score":0.46154398,"about_ca_system_score_codex":0.00018342282,"about_ca_system_score_gemma":0.00029252996,"threshold_uncertainty_score":0.7046085},"labels":[],"label_agreement":null},{"id":"W2111750260","doi":"10.1128/jvi.00641-08","title":"Autophagosome Supports Coxsackievirus B3 Replication in Host Cells","year":2008,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":376,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Michael Smith Health Research BC; Canadian Institutes of Health Research; Heart and Stroke Foundation of British Columbia and Yukon; Heart and Stroke Foundation of Canada","keywords":"Autophagosome; Autophagy; Biology; Viral replication; Coxsackievirus; Cell biology; Lysosome; Gene silencing; Small interfering RNA; Virology; RNA; Virus; Gene; Enterovirus; Biochemistry","score_opus":0.01889789698251333,"score_gpt":0.29682663648094015,"score_spread":0.27792873949842684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2111750260","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99609584,0.0014240753,0.00005914413,0.0013963534,0.00025891437,0.00011099567,0.0000020377645,0.000010572493,0.0006420753],"genre_scores_gemma":[0.9953223,0.0014187497,0.00020383683,0.0023784752,0.00026467192,0.000002728724,0.000002705152,0.00001332178,0.0003931939],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989437,0.00006400047,0.0005002974,0.00013855204,0.00017409606,0.00017936112],"domain_scores_gemma":[0.9991255,0.000043215536,0.00031598346,0.00029582754,0.00008372956,0.00013576614],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028385213,0.000092750895,0.00035798122,0.0002068773,0.000030384483,0.0000023135221,0.000094182746,0.00012252062,0.00046057074],"category_scores_gemma":[0.000059821883,0.00007584454,0.000119687196,0.00012270159,0.00009584359,0.000088036766,0.00001307378,0.0002816461,0.00006144115],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022098504,0.0013505245,0.061777573,0.00003826392,0.00019023502,0.011315847,0.0008580051,0.00003869027,0.90975624,0.00021434907,0.0067987237,0.0054517156],"study_design_scores_gemma":[0.0032428906,0.0013022932,0.88953817,0.000031071657,0.00006215379,0.0052025435,0.000021968322,0.00007278054,0.088063784,0.0003738426,0.01199539,0.00009314063],"about_ca_topic_score_codex":0.000009485002,"about_ca_topic_score_gemma":0.0000012175715,"teacher_disagreement_score":0.8277606,"about_ca_system_score_codex":0.000056962075,"about_ca_system_score_gemma":0.00018660013,"threshold_uncertainty_score":0.50429267},"labels":[],"label_agreement":null},{"id":"W2112128648","doi":"10.1161/01.res.0000029232.42227.16","title":"Inducible Expression of BNIP3 Provokes Mitochondrial Defects and Hypoxia-Mediated Cell Death of Ventricular Myocytes","year":2002,"lang":"en","type":"article","venue":"Circulation Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":316,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Myocyte; Programmed cell death; Mitochondrial permeability transition pore; Cell biology; Mitochondrion; Apoptosis; Biology; Hypoxia (environmental); Cytosol; Molecular biology; Internal medicine; Chemistry; Biochemistry; Medicine; Oxygen","score_opus":0.0775854348320213,"score_gpt":0.3335070785389533,"score_spread":0.255921643706932,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112128648","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937759,0.003714497,0.000050520142,0.000043270513,0.000041594358,0.0006203221,0.000006795679,0.000018536168,0.0017285455],"genre_scores_gemma":[0.9993118,0.00018840091,0.0001670197,0.000012845086,0.00009275555,0.000027729675,0.000026395623,0.000015020755,0.00015802537],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852604,0.0001500089,0.00024812348,0.00022533553,0.00063879887,0.00021169997],"domain_scores_gemma":[0.9989461,0.0002330607,0.00008898528,0.0002814746,0.0003136916,0.00013671254],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002483655,0.00008530959,0.00022302291,0.00030238114,0.00007134388,0.000010402435,0.00006954625,0.00012149011,0.00028586842],"category_scores_gemma":[0.00031960374,0.00007214485,0.00006390309,0.00038153888,0.00011242579,0.00008463213,0.000037200723,0.00017726941,0.000017455957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014825132,0.00045709687,0.090971075,0.00031632668,0.000023698762,0.00002803654,0.00040300708,0.0000503822,0.90654033,0.0000911399,0.0004112965,0.0005593755],"study_design_scores_gemma":[0.0026601066,0.00028560488,0.2185201,0.00019614112,0.00003263855,0.000007275787,0.00010397975,0.0022834586,0.7751852,0.00044554702,0.00019759288,0.00008231797],"about_ca_topic_score_codex":0.00002744905,"about_ca_topic_score_gemma":3.1460343e-7,"teacher_disagreement_score":0.13135508,"about_ca_system_score_codex":0.00003034492,"about_ca_system_score_gemma":0.00006399802,"threshold_uncertainty_score":0.31300586},"labels":[],"label_agreement":null},{"id":"W2112329697","doi":"10.1016/j.cell.2010.05.008","title":"Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations","year":2010,"lang":"en","type":"article","venue":"Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1204,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute on Aging; National Institutes of Health; NYU Langone Medical Center","keywords":"Autophagy; Biology; Lysosome; Presenilin; Proteolysis; Cell biology; TFEB; Protein subunit; Sequestosome 1; ATG16L1; Batten disease; Alzheimer's disease; Biochemistry; Enzyme; Apoptosis; Internal medicine","score_opus":0.008619855655993564,"score_gpt":0.2613236964601961,"score_spread":0.25270384080420255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112329697","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915423,0.0049277903,0.000024046234,0.0007272485,0.00008925666,0.00054315,0.00004456321,0.00010545213,0.0019961977],"genre_scores_gemma":[0.99490577,0.000082228325,0.0002678445,0.0001701408,0.000063313615,0.000053443146,0.00009714574,0.000027519112,0.004332595],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913377,0.00003076753,0.00020075034,0.00029725494,0.00013996517,0.000197523],"domain_scores_gemma":[0.9992852,0.00005225145,0.000089927686,0.00027387976,0.000054316995,0.000244409],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000066887376,0.00015437657,0.00022475951,0.000060563543,0.00012862262,0.000026183843,0.000054680153,0.00016264153,0.00050456345],"category_scores_gemma":[0.000040152532,0.00013165677,0.0000525711,0.00013781081,0.0002010662,0.00011694715,0.000033568376,0.0002587614,0.00003225895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002694523,0.0008058716,0.016656812,0.00018742088,0.00059902156,0.00028485068,0.0019037414,0.0000020503708,0.95818365,0.00019519038,0.003395131,0.017516831],"study_design_scores_gemma":[0.009320426,0.00051562756,0.1711567,0.000100759484,0.0017260041,0.00021314187,0.00068029447,0.005868003,0.7861103,0.0026597646,0.02093654,0.0007124765],"about_ca_topic_score_codex":0.000032118707,"about_ca_topic_score_gemma":0.000007955735,"teacher_disagreement_score":0.17207336,"about_ca_system_score_codex":0.0000053623667,"about_ca_system_score_gemma":0.000043029595,"threshold_uncertainty_score":0.55246156},"labels":[],"label_agreement":null},{"id":"W2112559300","doi":"10.1002/emmm.201100193","title":"Rab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress","year":2012,"lang":"en","type":"article","venue":"EMBO Molecular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institutes of Health; National Cancer Institute; Ovarian Cancer Research Fund; Cancer Research UK; U.S. Department of Defense","keywords":"Bioenergetics; Autophagy; Cell biology; Biology; Regulator; Cancer cell; Glycogen; Protein kinase B; Programmed cell death; Cancer research; Apoptosis; Biochemistry; Cancer; Mitochondrion; Signal transduction","score_opus":0.012132618522527486,"score_gpt":0.2727097770652122,"score_spread":0.2605771585426847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112559300","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92089474,0.07613085,0.00082049554,0.0008575647,0.00032681852,0.0005329061,0.000036346188,0.00009415645,0.000306122],"genre_scores_gemma":[0.99527735,0.0007068383,0.00036441296,0.001940709,0.0012971081,0.00009155444,0.000093473995,0.00006385473,0.00016468427],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99829006,0.00013988289,0.00030509013,0.00035427322,0.00045320115,0.00045748174],"domain_scores_gemma":[0.99873644,0.000094908835,0.0001282896,0.00041835202,0.00007250053,0.0005494822],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00023125668,0.0002967929,0.0004955759,0.00012303806,0.00012153341,0.00000980745,0.00010791149,0.00012794076,0.0010858016],"category_scores_gemma":[0.00013777732,0.00022558885,0.00008185872,0.0001853925,0.00021503703,0.000078028635,0.000063177926,0.00026327898,0.000018019393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021212736,0.00023877808,0.0119155245,0.0001485474,0.00038578486,0.0003271929,0.00173094,0.000008380428,0.97885925,0.000063458276,0.00047466514,0.00563535],"study_design_scores_gemma":[0.0031999748,0.00029437584,0.014859839,0.0007638423,0.00076932553,0.000020300045,0.0007387193,0.00016103109,0.9729356,0.00015217358,0.005799955,0.00030484132],"about_ca_topic_score_codex":0.0031295207,"about_ca_topic_score_gemma":0.0000098707405,"teacher_disagreement_score":0.075424016,"about_ca_system_score_codex":0.00005686503,"about_ca_system_score_gemma":0.00007162349,"threshold_uncertainty_score":0.9998273},"labels":[],"label_agreement":null},{"id":"W2112956181","doi":"10.1186/s13395-015-0033-y","title":"PGC-1α modulates denervation-induced mitophagy in skeletal muscle","year":2015,"lang":"en","type":"article","venue":"Skeletal Muscle","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":182,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Mitophagy; TFEB; Cell biology; Lysosome; Skeletal muscle; Mitochondrial biogenesis; Biology; Mitochondrion; Activator (genetics); Muscle atrophy; Endocrinology; Biochemistry; Receptor","score_opus":0.032835126883940385,"score_gpt":0.2920904046774404,"score_spread":0.2592552777935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112956181","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99241024,0.001098123,0.000052740583,0.0007499733,0.00051676464,0.00045008067,0.000009474082,0.00016963946,0.0045429845],"genre_scores_gemma":[0.9969232,0.00003380135,0.0004026478,0.0009404959,0.0005747403,0.000062328225,0.00008372907,0.000061487546,0.00091757125],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9980225,0.00007856668,0.00043391497,0.00046409082,0.00048696954,0.00051397004],"domain_scores_gemma":[0.9987377,0.00005440907,0.000101478894,0.0005399859,0.00014668735,0.00041975145],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002676021,0.00028538035,0.00041567578,0.00021848694,0.000069324204,0.00003290829,0.00019086403,0.00019585504,0.00030413954],"category_scores_gemma":[0.00016488697,0.00026566687,0.00020214301,0.00051055173,0.00008269817,0.00028744157,0.00006756436,0.00028997994,0.00040304067],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031459227,0.005049425,0.033628084,0.00041878255,0.00054977706,0.002090099,0.0045580645,0.0004776866,0.4095891,0.005953013,0.007827094,0.52954423],"study_design_scores_gemma":[0.007886547,0.00078803604,0.93464345,0.00014563328,0.00008479366,0.00003668276,0.0005626802,0.0027994642,0.020989552,0.0050531323,0.02633883,0.0006712208],"about_ca_topic_score_codex":0.00029896264,"about_ca_topic_score_gemma":0.000059446615,"teacher_disagreement_score":0.90101534,"about_ca_system_score_codex":0.00015693442,"about_ca_system_score_gemma":0.00024058686,"threshold_uncertainty_score":0.99997956},"labels":[],"label_agreement":null},{"id":"W2113190139","doi":"10.15252/embj.201489729","title":"USP8 regulates mitophagy by removing K6‐linked ubiquitin conjugates from parkin","year":2014,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":370,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute; McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"Parkin; Mitophagy; Biology; Ubiquitin; Ubiquitin-Protein Ligases; Cell biology; Ubiquitin ligase; Genetics; Autophagy; Parkinson's disease; Gene; Apoptosis; Internal medicine","score_opus":0.008652826280570132,"score_gpt":0.24632376505137393,"score_spread":0.2376709387708038,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2113190139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867095,0.006126728,0.00034879995,0.0038199923,0.00041661045,0.00014597847,0.000012241005,0.00007005693,0.0023500952],"genre_scores_gemma":[0.9916408,0.00042581357,0.00038945925,0.003467801,0.0021760317,0.000004409738,0.000025794148,0.000042272466,0.0018276406],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984064,0.00025107432,0.00040979325,0.00020118924,0.00036522347,0.00036630232],"domain_scores_gemma":[0.99863154,0.00035093277,0.00023801785,0.00041405496,0.00009276619,0.00027268482],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00065366545,0.00020680977,0.00036096358,0.000051520132,0.00034263107,0.00010098471,0.0002906983,0.000090879286,0.0015670831],"category_scores_gemma":[0.00017312886,0.00012886083,0.0001915399,0.000093084185,0.0001439104,0.00010372538,0.000043362557,0.0005168737,0.0001513258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022775622,0.0006241893,0.013080866,0.000063579995,0.0019904461,0.0005487957,0.003573315,0.00005150936,0.6924737,0.0015307602,0.19794865,0.08583665],"study_design_scores_gemma":[0.012577251,0.0010674181,0.104548894,0.0011045393,0.00110741,0.002174245,0.0011149399,0.0048907683,0.5896898,0.097505026,0.18323575,0.0009839712],"about_ca_topic_score_codex":0.000050099683,"about_ca_topic_score_gemma":0.0000027278777,"teacher_disagreement_score":0.1027839,"about_ca_system_score_codex":0.000046720023,"about_ca_system_score_gemma":0.00007498374,"threshold_uncertainty_score":0.9993456},"labels":[],"label_agreement":null},{"id":"W2113292346","doi":"10.1038/sj.cdd.4402176","title":"Oxidative repression of NHE1 gene expression involves iron-mediated caspase activity","year":2007,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National University of Singapore","keywords":"Psychological repression; Caspase; Gene silencing; Chemistry; Cell biology; Apoptosis; Molecular biology; Repressor; Downregulation and upregulation; Gene expression; Biology; Biochemistry; Programmed cell death; Gene","score_opus":0.01676732137972893,"score_gpt":0.26870644935913984,"score_spread":0.2519391279794109,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2113292346","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99190325,0.0007995321,0.006273332,0.000016405525,0.000080445425,0.00024350667,0.000013255968,0.0000365299,0.00063374813],"genre_scores_gemma":[0.9987403,0.00036621714,0.00034861366,0.000056433353,0.00007123224,0.000005965365,0.00019315138,0.000012175358,0.00020588921],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992071,0.00003972462,0.00018837929,0.00022216975,0.0001894925,0.00015315072],"domain_scores_gemma":[0.9993109,0.00009286226,0.00016571172,0.00020070565,0.000062459054,0.00016733461],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011604653,0.00012574747,0.00020113378,0.00009867044,0.00006737967,0.00000741334,0.000031678283,0.00011419812,0.0000887306],"category_scores_gemma":[0.000045001838,0.00009667919,0.000054977416,0.0000758248,0.00003446795,0.00010352914,0.000029478071,0.000092407165,0.0000042826455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006967759,0.00037975027,0.041333474,0.0001045435,0.0000145617305,0.000012669294,0.00040081446,6.825952e-7,0.9534738,0.0000141958835,0.00004457464,0.0035241628],"study_design_scores_gemma":[0.0010550785,0.000097071876,0.38293326,0.000050205042,0.00004531832,0.0000013122752,0.000052087224,0.00027136822,0.6153294,0.00009686064,0.000010792274,0.00005728406],"about_ca_topic_score_codex":0.000026633783,"about_ca_topic_score_gemma":0.000001982011,"teacher_disagreement_score":0.34159976,"about_ca_system_score_codex":0.000023326113,"about_ca_system_score_gemma":0.000025442489,"threshold_uncertainty_score":0.3942463},"labels":[],"label_agreement":null},{"id":"W2114645683","doi":"10.1158/1078-0432.ccr-12-3114","title":"Blocked Autophagy Using Lysosomotropic Agents Sensitizes Resistant Prostate Tumor Cells to the Novel Akt Inhibitor AZD5363","year":2012,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Astex Pharmaceuticals; AstraZeneca","keywords":"Autophagy; Protein kinase B; Prostate; Cancer research; PI3K/AKT/mTOR pathway; Medicine; Chemistry; Biology; Cell biology; Signal transduction; Cancer; Internal medicine; Apoptosis; Biochemistry","score_opus":0.27633364181972353,"score_gpt":0.5225578416554204,"score_spread":0.24622419983569688,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114645683","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909215,0.0023534778,0.000027413966,0.0035295628,0.0011556422,0.0015352881,0.00010553826,0.000066263616,0.0003053115],"genre_scores_gemma":[0.9884546,0.0003991466,0.00036713804,0.0036271757,0.003813495,0.00013797624,0.0000099683175,0.00007116991,0.0031193518],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99567956,0.0005536667,0.0007601718,0.0005485896,0.0012503967,0.0012076369],"domain_scores_gemma":[0.9968718,0.00063952844,0.00011783939,0.0008759991,0.00049319526,0.0010015795],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0029026747,0.00023615868,0.0005225018,0.00015910329,0.00041274697,0.000067855144,0.00031438953,0.00014212549,0.00071340904],"category_scores_gemma":[0.0006577747,0.00015579489,0.0002543823,0.00069777214,0.0004665236,0.00010349968,0.00030780205,0.0009936965,0.0003915307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015898418,0.0051599406,0.030319788,0.00066088187,0.0011961281,0.00089312455,0.003131101,0.00010010321,0.83116984,0.00050201983,0.087628596,0.023340082],"study_design_scores_gemma":[0.010196982,0.0021730151,0.28082472,0.0010537714,0.00038600503,0.000054526623,0.00073423324,0.0014856956,0.40620235,0.00023236354,0.29589096,0.00076537713],"about_ca_topic_score_codex":0.00037950836,"about_ca_topic_score_gemma":0.000029169963,"teacher_disagreement_score":0.42496747,"about_ca_system_score_codex":0.0003159343,"about_ca_system_score_gemma":0.0008257922,"threshold_uncertainty_score":0.7811328},"labels":[],"label_agreement":null},{"id":"W2114673876","doi":"10.15252/embr.201440006","title":"Phosphorylation of the exchange factor DENND3 by ULK in response to starvation activates Rab12 and induces autophagy","year":2015,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Autophagy; Guanine nucleotide exchange factor; Cell biology; Phosphorylation; Kinase; Chemistry; Function (biology); Biology; GTPase; Biochemistry","score_opus":0.026197402446955672,"score_gpt":0.2912697547291347,"score_spread":0.265072352282179,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114673876","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99765426,0.00092903274,0.000015261321,0.00057089224,0.00015905927,0.0004297019,0.0000060570687,0.000021199603,0.00021452221],"genre_scores_gemma":[0.99875474,0.000018301891,0.00004811306,0.00026092806,0.000032993055,0.00002351059,0.0000102377435,0.000012145086,0.00083903753],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991095,0.00007714027,0.00026641664,0.00017426195,0.00026191812,0.0001107743],"domain_scores_gemma":[0.9993327,0.000055872362,0.00017094352,0.00025254258,0.00007760668,0.00011031435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004131188,0.00009040425,0.00017524594,0.000076798926,0.000024367184,0.000008512029,0.00003199467,0.00007013093,0.000063587904],"category_scores_gemma":[0.00039221943,0.00006424937,0.000027733897,0.00020624611,0.000030407442,0.0001055585,0.00002858584,0.00007712027,0.0000015696485],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0051757423,0.0003914799,0.16271515,0.0000777697,0.000086355074,0.00026529512,0.0133296475,0.000014815752,0.7983302,0.00003469508,0.0066754767,0.012903414],"study_design_scores_gemma":[0.0005376577,0.00019838575,0.57352155,0.00006259046,0.000012971627,0.000030920502,0.00020246906,0.000013882607,0.42141092,0.00049510907,0.0034456819,0.00006783186],"about_ca_topic_score_codex":0.00012686796,"about_ca_topic_score_gemma":0.000008084825,"teacher_disagreement_score":0.41080645,"about_ca_system_score_codex":0.000075150485,"about_ca_system_score_gemma":0.00014301653,"threshold_uncertainty_score":0.2620013},"labels":[],"label_agreement":null},{"id":"W2114938079","doi":"10.2174/156652410791608252","title":"Autophagy and Crohns Disease: At the Crossroads of Infection, Inflammation, Immunity, and Cancer","year":2010,"lang":"en","type":"review","venue":"Current Molecular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Cancer Research; National Institute of General Medical Sciences; Alfred Benzon Foundation; Institut National Du Cancer","keywords":"ATG16L1; Autophagy; Inflammatory bowel disease; Ulcerative colitis; Disease; Inflammation; Immunology; Immunity; Cancer; Medicine; Crohn's disease; Pathogenesis; Colorectal cancer; Immune system; Biology; Genetics; Internal medicine","score_opus":0.033145731601403036,"score_gpt":0.3930844421672426,"score_spread":0.35993871056583954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114938079","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.018917728,0.97849256,0.000046915815,0.00049244735,0.00067748746,0.0011706783,0.000055252345,0.00003789716,0.000109030385],"genre_scores_gemma":[0.0011686239,0.9973852,0.000004636834,0.00010031205,0.0005178139,0.00021464255,0.00033988015,0.000055630764,0.00021322726],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99812514,0.0001650294,0.00067755725,0.0003762794,0.0004187503,0.00023725198],"domain_scores_gemma":[0.99813205,0.00012479108,0.00046821294,0.0007266364,0.00020599803,0.0003423057],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003201531,0.00043939543,0.001283976,0.00020218294,0.0001880108,0.0000150789765,0.000125124,0.00020330673,0.0003755212],"category_scores_gemma":[0.00027265731,0.00025534938,0.00023110956,0.00031255902,0.0010293967,0.000051369974,0.00019137589,0.0007011155,0.000006113879],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038683458,0.00006316299,0.00045135003,0.016330699,0.00031378036,0.00003276644,0.00015492152,2.2424034e-7,0.00017597387,0.00045705592,0.00047981355,0.9815016],"study_design_scores_gemma":[0.001037977,0.00008568944,0.0074346303,0.013920607,0.0036351823,0.00007499843,0.0000025686265,0.0000078578705,0.00011717391,0.00013627231,0.97334063,0.00020639614],"about_ca_topic_score_codex":0.000096368334,"about_ca_topic_score_gemma":0.0000122243155,"teacher_disagreement_score":0.98129517,"about_ca_system_score_codex":0.0000679305,"about_ca_system_score_gemma":0.00043361966,"threshold_uncertainty_score":0.99998987},"labels":[],"label_agreement":null},{"id":"W2115261650","doi":"10.1186/1758-5996-5-23","title":"The polygenetically inherited metabolic syndrome of male WOKW rats is associated with enhanced autophagy in adipose tissue","year":2013,"lang":"en","type":"article","venue":"Diabetology & Metabolic Syndrome","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"Adipose tissue; Autophagy; ATG5; Insulin resistance; Endocrinology; Internal medicine; Medicine; Western blot; BECN1; Apoptosis; Biology; Insulin; Gene; Biochemistry","score_opus":0.008060825754233465,"score_gpt":0.2506683731594265,"score_spread":0.24260754740519305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115261650","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9676728,0.028937468,0.000031645646,0.0008629438,0.0002648844,0.0014256707,0.000042683485,0.00011372097,0.0006481429],"genre_scores_gemma":[0.994352,0.0010762595,0.00027559782,0.0014387849,0.00003536234,0.00053936424,0.000057365218,0.00009689375,0.0021284001],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.996148,0.00047226663,0.0010015952,0.0006897811,0.0005548345,0.0011335043],"domain_scores_gemma":[0.9974585,0.00038234008,0.00040234602,0.001058827,0.00030086882,0.00039707255],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004627388,0.00054390315,0.002276384,0.00040718142,0.00015252811,0.000037438615,0.0005208053,0.00044877292,0.0024224077],"category_scores_gemma":[0.00026672543,0.00037994533,0.00022048756,0.001339242,0.0007564466,0.00018638175,0.00010360893,0.00052065996,0.00035570006],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014524427,0.007662402,0.1802966,0.00034812,0.021120798,0.0077975094,0.00592696,0.000055578785,0.683642,0.009987826,0.0016137472,0.08009596],"study_design_scores_gemma":[0.003316135,0.00067330414,0.91593724,0.00012629651,0.0006374388,0.0010797166,0.00009097855,0.00008876005,0.07553897,0.00069737696,0.0014358417,0.0003779264],"about_ca_topic_score_codex":0.00024635385,"about_ca_topic_score_gemma":0.000042870717,"teacher_disagreement_score":0.73564065,"about_ca_system_score_codex":0.00004329894,"about_ca_system_score_gemma":0.00032159864,"threshold_uncertainty_score":0.99986523},"labels":[],"label_agreement":null},{"id":"W2116799923","doi":"10.1371/journal.pone.0003391","title":"Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn's Disease Associated ATG16L1 Variant","year":2008,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":327,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute; Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Deutsche Forschungsgemeinschaft; Crohn's and Colitis Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Crohn's and Colitis Foundation of America","keywords":"ATG16L1; Autophagy; Crohn's disease; NOD2; Inflammatory bowel disease; Disease; Biology; Medicine; Immunology; Genetics; Internal medicine","score_opus":0.037249436537248444,"score_gpt":0.24077921382214004,"score_spread":0.2035297772848916,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2116799923","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99728906,0.0012186118,0.000022715034,0.00021407723,0.000032903637,0.00062640774,0.00024833798,0.00019328619,0.00015458204],"genre_scores_gemma":[0.99771655,0.00015539542,0.0003288306,0.00045896182,0.00012259756,0.000053459866,0.0004896427,0.000057073245,0.000617491],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981362,0.0001388169,0.00040197378,0.00035153923,0.00061373704,0.00035773613],"domain_scores_gemma":[0.9983994,0.000045954475,0.00019431321,0.0005776888,0.00017897773,0.00060369715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017178775,0.00022765489,0.0005665596,0.000095515956,0.00011109675,0.000008577914,0.00016060878,0.00016423236,0.0005242132],"category_scores_gemma":[0.00024198786,0.00021350963,0.00014650245,0.0002658255,0.00009587836,0.00013296733,0.000035025736,0.00020898497,0.000038999766],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011500281,0.019472508,0.0048133093,0.00014238132,0.0013010073,0.004537369,0.00073143194,0.000001130279,0.9669524,0.00006084846,0.0002954798,0.000542106],"study_design_scores_gemma":[0.006426499,0.0013217638,0.57945454,0.00038787356,0.0013972985,0.000022330836,0.000050627656,0.0037377551,0.40621012,0.00046449446,0.000051145696,0.00047555132],"about_ca_topic_score_codex":0.000049674654,"about_ca_topic_score_gemma":0.000001324771,"teacher_disagreement_score":0.5746412,"about_ca_system_score_codex":0.000087651446,"about_ca_system_score_gemma":0.00032885018,"threshold_uncertainty_score":0.870667},"labels":[],"label_agreement":null},{"id":"W2117004136","doi":"10.1128/mcb.00930-12","title":"Glycogen Synthase Kinase 3 Inhibition Promotes Lysosomal Biogenesis and Autophagic Degradation of the Amyloid-β Precursor Protein","year":2012,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":159,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Deutsche Forschungsgemeinschaft; Imperial College London; Institute of Genetics; Cancer Research UK","keywords":"GSK-3; Biology; Autophagy; Glycogen synthase; Biogenesis; GSK3B; Cell biology; Degradation (telecommunications); Protein degradation; Kinase; Amyloid (mycology); Biochemistry; Protein kinase A; Phosphorylation; Gene","score_opus":0.009541701649107278,"score_gpt":0.2356341816749001,"score_spread":0.22609248002579282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117004136","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98745143,0.010701187,0.00078703347,0.00023042949,0.00004790589,0.00064121245,0.000030428653,0.00002036818,0.00009000697],"genre_scores_gemma":[0.999277,0.000039590323,0.00025216455,0.00014752329,0.000044934022,0.00004733307,0.00008617129,0.000014661009,0.0000906102],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992102,0.00014511474,0.00017254282,0.00018995894,0.00008184161,0.00020034105],"domain_scores_gemma":[0.9995452,0.0000130993885,0.0000877056,0.00020898147,0.000036388425,0.000108616645],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013706488,0.0001360149,0.00019182338,0.000057339446,0.00006826231,0.000005613941,0.000038745668,0.00013392884,0.000037710914],"category_scores_gemma":[0.000041566407,0.000092154114,0.000079206584,0.00010918598,0.00019772042,0.000038570048,0.00004775954,0.000066404995,0.000003214994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010035091,0.00017839072,0.008184093,0.00008281701,0.00006960314,0.000012855323,0.000081113634,6.999233e-8,0.9856003,0.0015836526,0.0000039768906,0.004102769],"study_design_scores_gemma":[0.00077918766,0.0002452888,0.006968115,0.000047319503,0.00014769606,0.000041430263,0.000024272951,0.00003203388,0.99081504,0.00057080225,0.00023161985,0.00009716605],"about_ca_topic_score_codex":0.000026742484,"about_ca_topic_score_gemma":7.687701e-7,"teacher_disagreement_score":0.011825585,"about_ca_system_score_codex":0.000010966919,"about_ca_system_score_gemma":0.00003297212,"threshold_uncertainty_score":0.37579358},"labels":[],"label_agreement":null},{"id":"W2117137379","doi":"10.1073/pnas.0811045106","title":"Activation of antibacterial autophagy by NADPH oxidases","year":2009,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":546,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"Ontario Innovation Trust; Burroughs Wellcome Fund","keywords":"Phagosome; Autophagy; NADPH oxidase; Cell biology; Reactive oxygen species; Phagocytosis; Biology; Receptor; Signal transduction; Cytosol; Chemistry; Microbiology; Biochemistry; Apoptosis; Enzyme","score_opus":0.028269351419648266,"score_gpt":0.32202784983746213,"score_spread":0.2937584984178139,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117137379","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939144,0.000107938606,8.7995375e-7,0.0025295059,0.000012726561,0.00014114112,0.000013782719,0.000009826726,0.003269754],"genre_scores_gemma":[0.99880743,0.000032765543,0.00033296822,0.00061266194,0.0000814784,0.0000016691296,5.052055e-7,0.0000021945996,0.00012831512],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99869514,0.0000033002202,0.00026449954,0.00013488997,0.0008090812,0.00009310979],"domain_scores_gemma":[0.99933845,0.00004379582,0.00036842306,0.0000069065823,0.00021141558,0.000030983407],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037559145,0.000068026675,0.00016352149,0.00010243667,0.000069944435,0.000006461326,0.00026229917,0.0000636544,0.00003963942],"category_scores_gemma":[0.0002588384,0.000044222754,0.000073349845,0.0004311958,0.00038552575,0.00029373137,0.000020287467,0.000073799114,4.53121e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008379925,0.0001341204,0.0010675527,0.000032692264,0.000014261239,3.1835827e-9,0.00006338389,0.000002091709,0.9853823,0.011035325,0.0012384105,0.0009460145],"study_design_scores_gemma":[0.00031566186,0.00013320279,0.18338075,0.00009629769,0.000012580279,0.0000025314698,0.000028781526,0.00007202602,0.802771,0.0130055295,0.00014862233,0.00003301278],"about_ca_topic_score_codex":0.000002846717,"about_ca_topic_score_gemma":1.5715005e-9,"teacher_disagreement_score":0.18261135,"about_ca_system_score_codex":0.000017846562,"about_ca_system_score_gemma":0.000045932786,"threshold_uncertainty_score":0.18033515},"labels":[],"label_agreement":null},{"id":"W2117217282","doi":"10.1091/mbc.e12-08-0607","title":"Regulation of mitophagy by the Gp78 E3 ubiquitin ligase","year":2013,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":194,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Ubiquitin ligase; Biology; MFN2; Cell biology; Mitophagy; Ubiquitin; Parkin; mitochondrial fusion; Small interfering RNA; Gene knockdown; MFN1; Small hairpin RNA; Mitochondrion; Autophagy; Transfection; Biochemistry; Internal medicine; Mitochondrial DNA; Apoptosis","score_opus":0.004163885958993797,"score_gpt":0.2358370942157311,"score_spread":0.2316732082567373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117217282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99245083,0.002946952,0.00027318634,0.0019854668,0.00007501311,0.0003603041,0.000008952718,0.000009454438,0.0018898129],"genre_scores_gemma":[0.99736595,0.000033005625,0.000113910326,0.0010993717,0.000028147924,0.00001585012,0.000020206664,0.000010446928,0.0013131362],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993569,0.00012070269,0.00019438591,0.00011985811,0.00008404361,0.0001240707],"domain_scores_gemma":[0.9992468,0.000039582952,0.00014790657,0.00046420077,0.00006622575,0.000035289762],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000098711804,0.00008710633,0.00016919125,0.00002198055,0.00003449559,0.0000018900914,0.00019404378,0.000098260265,0.00026411307],"category_scores_gemma":[0.000028481574,0.00004629318,0.00014738241,0.00008378218,0.000261526,0.000011020439,0.00005040781,0.00008327933,0.00002385516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030402769,0.00008930624,0.0006492599,0.000021930482,0.000048248297,8.4944236e-7,0.00005566496,0.0000043075397,0.99443096,0.0003502272,0.0032444193,0.0010744402],"study_design_scores_gemma":[0.0005530142,0.00013023627,0.008464662,0.000016605678,0.00005213765,0.000004661823,0.000026061716,0.000058992853,0.9856941,0.003818882,0.0011384122,0.000042239015],"about_ca_topic_score_codex":0.00006587899,"about_ca_topic_score_gemma":3.7661928e-7,"teacher_disagreement_score":0.00873685,"about_ca_system_score_codex":0.000008214628,"about_ca_system_score_gemma":0.000029725437,"threshold_uncertainty_score":0.2891853},"labels":[],"label_agreement":null},{"id":"W2117351967","doi":"10.1093/hmg/dds048","title":"Bcl-2-associated autophagy regulator Naf-1 required for maintenance of skeletal muscle","year":2012,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Christie (Canada); McGill University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Regulator; Autophagy; Skeletal muscle; Cell biology; Endocrinology; Genetics; Apoptosis; Gene","score_opus":0.02073946079961242,"score_gpt":0.2991019171254871,"score_spread":0.2783624563258747,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117351967","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917119,0.004537633,0.0022860013,0.000057501056,0.000161926,0.0005868002,0.000033861026,0.00006322232,0.0005611642],"genre_scores_gemma":[0.9961854,0.00004984722,0.0021310267,0.00043954156,0.00016045722,0.000032450764,0.00009608195,0.00006689288,0.0008382672],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986316,0.000047524893,0.00035964316,0.00021617742,0.00027907372,0.00046596682],"domain_scores_gemma":[0.99890995,0.000022265365,0.00018353593,0.0004909884,0.00017595454,0.00021733406],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016894487,0.00018768654,0.00034615622,0.00007122087,0.00007945922,0.0000075328185,0.00013175113,0.00015186286,0.00010676311],"category_scores_gemma":[0.000073957395,0.00018262808,0.00027504656,0.00012450812,0.00012374089,0.00003512387,0.00003832067,0.00008368862,0.000012908758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048393642,0.0005816009,0.00080787414,0.00011272561,0.00028434096,0.00001952189,0.00029254772,0.0000110436895,0.989271,0.0048784898,0.0010180685,0.0026743812],"study_design_scores_gemma":[0.00592637,0.0009696409,0.4122008,0.00017832033,0.0005600427,0.000017936454,0.0000902774,0.0003401243,0.56018525,0.0047563883,0.014311157,0.00046365437],"about_ca_topic_score_codex":0.0000043499663,"about_ca_topic_score_gemma":0.000001184513,"teacher_disagreement_score":0.42908576,"about_ca_system_score_codex":0.00006277623,"about_ca_system_score_gemma":0.00006838909,"threshold_uncertainty_score":0.7447357},"labels":[],"label_agreement":null},{"id":"W2118598201","doi":"10.1080/15548627.2015.1067364","title":"Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson disease","year":2015,"lang":"en","type":"review","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":264,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Autophagy; Lysosome; PINK1; Mitophagy; LRRK2; Biology; Parkinson's disease; Genetics; Disease; Cell biology; Pathogenesis; Lafora disease; Mechanism (biology); ATG16L1; Gene; Mutation; Immunology; Phosphorylation; Enzyme; Biochemistry; Phosphatase; Medicine","score_opus":0.029506865923454705,"score_gpt":0.31585673805359343,"score_spread":0.28634987213013874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118598201","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005447969,0.98590606,6.370564e-7,0.00020021967,0.00033111134,0.0026125293,0.00013832768,0.00006497392,0.0052981395],"genre_scores_gemma":[0.0596245,0.9368829,0.000019189882,0.00066751376,0.00047772506,0.0004938376,0.000031302858,0.00014318108,0.0016598294],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99667,0.0005234264,0.0007810807,0.0007078423,0.00081323116,0.0005043891],"domain_scores_gemma":[0.99692935,0.0002553826,0.00048756157,0.0017922263,0.00017585859,0.0003596201],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003643185,0.0006542442,0.0018152962,0.0002516417,0.00009931503,0.000025031131,0.0006514691,0.00033458142,0.00026636274],"category_scores_gemma":[0.00025345496,0.00033860066,0.0012132495,0.0007728279,0.00028826582,0.000043190397,0.00016838341,0.0008464084,0.00025528512],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004291354,0.0020445467,0.00038408252,0.0047812415,0.0012289381,0.00087607454,0.0010244618,0.000011988624,0.000025617652,0.017700134,0.0008164364,0.9706773],"study_design_scores_gemma":[0.0009074179,0.00025404716,0.011135783,0.0067845164,0.0011242469,0.00005298866,0.00015104475,0.000063505424,0.00022982818,0.005216424,0.97371924,0.00036094777],"about_ca_topic_score_codex":0.000063527754,"about_ca_topic_score_gemma":0.0000032502537,"teacher_disagreement_score":0.97290283,"about_ca_system_score_codex":0.00070265646,"about_ca_system_score_gemma":0.002706272,"threshold_uncertainty_score":0.9999066},"labels":[],"label_agreement":null},{"id":"W2118705984","doi":"10.1530/jme-13-0241","title":"Autophagy in the endocrine glands","year":2014,"lang":"en","type":"review","venue":"Journal of Molecular Endocrinology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Autophagy; Endocrine system; Biology; Hormone; Cell biology; Enteroendocrine cell; Context (archaeology); Endocrine gland; Intracellular; Endocrinology; Biochemistry; Apoptosis","score_opus":0.028660395330273942,"score_gpt":0.37337698639584754,"score_spread":0.3447165910655736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118705984","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007801936,0.9962421,0.00014941349,0.00041716453,0.0004188973,0.0004083771,0.0000037490213,0.000012004478,0.0015681174],"genre_scores_gemma":[0.0025275953,0.99531776,0.00015957908,0.001221874,0.00055619207,0.000027214684,0.000018399516,0.00005243809,0.00011897638],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969861,0.0006614917,0.0012162683,0.00023082546,0.00041698708,0.0004883356],"domain_scores_gemma":[0.9980871,0.00026205555,0.0008340161,0.00058572675,0.00010507648,0.00012604384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036533232,0.0003897678,0.002477718,0.00061585795,0.000029207848,0.00001754987,0.00061511184,0.00020032571,0.00013959645],"category_scores_gemma":[0.0001959558,0.00021887051,0.0012017813,0.00031833193,0.000105341955,0.00003254699,0.000060379905,0.0013382691,0.000051765055],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009269926,0.00034984795,0.00001700063,0.003542007,0.00089370285,0.037499208,0.000053906457,0.0000015553718,0.000029319152,0.0029249142,0.0011725868,0.95342326],"study_design_scores_gemma":[0.0016751394,0.00068953284,0.00006114143,0.0023760248,0.0014658825,0.038584888,0.000013185256,0.0000011044278,0.00008310538,0.00037962245,0.954512,0.00015834614],"about_ca_topic_score_codex":0.0000043029877,"about_ca_topic_score_gemma":8.631337e-7,"teacher_disagreement_score":0.95333946,"about_ca_system_score_codex":0.00009445558,"about_ca_system_score_gemma":0.0004628261,"threshold_uncertainty_score":0.89252806},"labels":[],"label_agreement":null},{"id":"W2119515848","doi":"10.1161/circresaha.116.303805","title":"The Role of Autophagy in Vascular Biology","year":2015,"lang":"en","type":"review","venue":"Circulation Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":248,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"National Institutes of Health; Fondation Leducq; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Paracrine signalling; Cell biology; Biology; Angiogenesis; Vascular smooth muscle; Endothelium; Autophagosome; Flux (metallurgy); Neuroscience; Cancer research; Chemistry; Smooth muscle; Receptor; Endocrinology; Biochemistry","score_opus":0.1821743050049583,"score_gpt":0.5061740378045134,"score_spread":0.32399973279955513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119515848","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00046545995,0.9946112,0.0000049622545,0.00002106613,0.00006010244,0.0010881065,0.000007839253,0.000014287282,0.0037269515],"genre_scores_gemma":[0.0058852932,0.9935185,0.0000073561546,0.0000054264033,0.00014233547,0.00016018508,0.00012061031,0.000029194325,0.00013112651],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975632,0.000827366,0.00048985105,0.00026406517,0.0005311272,0.00032437872],"domain_scores_gemma":[0.99830556,0.00043069807,0.00011606222,0.00065489515,0.00037614245,0.00011662514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0026308522,0.00013974644,0.00081820984,0.0004230537,0.000075240736,0.000014377332,0.00024955094,0.0003117419,0.00009795771],"category_scores_gemma":[0.00035301465,0.00008742137,0.00028188174,0.00080850156,0.00024127492,0.000025350952,0.000070219234,0.0005785977,0.00012146029],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010453046,0.00006952543,0.00025070366,0.0013876199,0.00014346813,0.000006747308,0.000048512527,0.0000025009329,0.000008410059,0.004243285,0.00006985914,0.9937589],"study_design_scores_gemma":[0.00033932785,0.00005351336,0.0012676545,0.0013703527,0.00008062041,0.0000045594716,0.000036873764,0.00016399102,0.0000039551655,0.0066910763,0.98991644,0.0000716389],"about_ca_topic_score_codex":0.000070909926,"about_ca_topic_score_gemma":0.000004283509,"teacher_disagreement_score":0.9936873,"about_ca_system_score_codex":0.00020356617,"about_ca_system_score_gemma":0.0012662236,"threshold_uncertainty_score":0.356494},"labels":[],"label_agreement":null},{"id":"W2119683726","doi":"10.1161/circresaha.114.302734","title":"Mitochondrial Contagion Induced by Parkin Deficiency in <i>Drosophila</i> Hearts and Its Containment by Suppressing Mitofusin","year":2013,"lang":"en","type":"article","venue":"Circulation Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":157,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Heart, Lung, and Blood Institute","keywords":"Parkin; Mitophagy; Mitochondrion; Biology; PINK1; Cell biology; Cardiomyopathy; mitochondrial fusion; Mitochondrial DNA; Genetics; Internal medicine; Heart failure; Autophagy; Medicine; Parkinson's disease; Disease; Apoptosis","score_opus":0.049001965377749465,"score_gpt":0.34953637439911117,"score_spread":0.3005344090213617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119683726","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916319,0.0035662123,0.000033658805,0.002461266,0.00009484499,0.0014412962,0.000009198496,0.000027470438,0.00073414977],"genre_scores_gemma":[0.99897796,0.00008439407,0.000014414537,0.00035250458,0.000107246065,0.00016480463,0.0000855925,0.00002149632,0.00019156387],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9979594,0.00025387306,0.00029909168,0.00037898094,0.0006774194,0.00043124365],"domain_scores_gemma":[0.99916726,0.00014957947,0.000046952242,0.00021363089,0.00018720915,0.00023535824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003581384,0.00012932358,0.00022022729,0.00017105439,0.00016681278,0.00010053419,0.00007311851,0.00014829877,0.00024783344],"category_scores_gemma":[0.00012457199,0.00012276873,0.000037648057,0.00029369022,0.00010335325,0.00023599528,0.00004131772,0.00033959886,0.00006383103],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011970803,0.00027257082,0.016551176,0.000045305005,0.000013832703,0.0000132400255,0.00031367087,0.0000048403344,0.9725247,0.00013113742,0.007961739,0.0020481066],"study_design_scores_gemma":[0.016398463,0.00080536504,0.7338151,0.00050365605,0.000047705522,0.00004944281,0.0006529638,0.014583997,0.22430912,0.0037204218,0.0044234977,0.00069026975],"about_ca_topic_score_codex":0.0002699889,"about_ca_topic_score_gemma":0.000005828757,"teacher_disagreement_score":0.74821556,"about_ca_system_score_codex":0.00015086122,"about_ca_system_score_gemma":0.00010633388,"threshold_uncertainty_score":0.50063634},"labels":[],"label_agreement":null},{"id":"W2120204078","doi":"10.1111/j.1365-2893.2011.01530.x","title":"Virus-triggered autophagy in viral hepatitis - possible novel strategies for drug development","year":2011,"lang":"en","type":"review","venue":"Journal of Viral Hepatitis","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research Manitoba; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"","keywords":"Autophagy; Homeostasis; Biology; Hepatitis C virus; Disease; Drug development; Drug; Virus; Immunology; Virology; Medicine; Cell biology; Pharmacology; Genetics; Apoptosis; Pathology","score_opus":0.047604243975815426,"score_gpt":0.3409367641357718,"score_spread":0.29333252015995637,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120204078","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012375114,0.98345745,0.0007087045,0.000022511742,0.0010518308,0.0013373233,0.00023217977,0.000039242965,0.00077564706],"genre_scores_gemma":[0.0020570685,0.98835856,0.007008797,0.00020599995,0.00079712085,0.00015163395,0.0001418856,0.00013800821,0.0011409438],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9957006,0.00013577325,0.0025343127,0.000421311,0.00057261507,0.00063537306],"domain_scores_gemma":[0.99700963,0.00017353136,0.0017346519,0.0003849571,0.00033495086,0.00036227363],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006412414,0.00073152845,0.0032255133,0.0008876083,0.00012531663,0.00010089738,0.0004926508,0.0004543147,0.00046261135],"category_scores_gemma":[0.00007912382,0.0005749391,0.0012671553,0.00034793536,0.00011124908,0.00055436476,0.000071994975,0.0008574264,0.00005320087],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043942526,0.0012873884,0.00046503817,0.011018327,0.0014182837,0.0009927886,0.0009876628,0.0000015565261,0.000034573593,0.0016594814,0.0028797027,0.9788158],"study_design_scores_gemma":[0.0038795634,0.0011980721,0.002734151,0.021228129,0.0013126363,0.0006080366,0.000039699808,0.000022991126,0.00034381167,0.0015102577,0.9663634,0.00075926026],"about_ca_topic_score_codex":0.00082175474,"about_ca_topic_score_gemma":0.0005488297,"teacher_disagreement_score":0.9780565,"about_ca_system_score_codex":0.00068532035,"about_ca_system_score_gemma":0.0043411674,"threshold_uncertainty_score":0.9996702},"labels":[],"label_agreement":null},{"id":"W2120987375","doi":"10.1152/ajpregu.00187.2014","title":"Autophagy is essential to support skeletal muscle plasticity in response to endurance exercise","year":2014,"lang":"en","type":"review","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":142,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Autophagy; Mitophagy; mTORC1; Skeletal muscle; Cell biology; Lysosome; Endurance training; Biology; Proteasome; Protein turnover; Protein degradation; Ubiquitin; Signal transduction; PI3K/AKT/mTOR pathway; Endocrinology; Protein biosynthesis; Biochemistry; Gene; Apoptosis","score_opus":0.027633389858192834,"score_gpt":0.358023073993954,"score_spread":0.33038968413576114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120987375","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8361291,0.1619207,0.00016516709,0.0001328018,0.00035406052,0.0011014163,0.00012128012,0.000023580063,0.00005189667],"genre_scores_gemma":[0.7984143,0.19847672,0.0005587875,0.0014679525,0.00061864353,0.00017847262,0.000041790314,0.00006769056,0.00017566112],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99482507,0.0015574176,0.001586187,0.000982596,0.00034650814,0.0007022451],"domain_scores_gemma":[0.99594223,0.000878324,0.0014925441,0.0005323403,0.00047280578,0.00068172504],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039552333,0.0010145496,0.0069445455,0.000881841,0.00011910312,0.000018969164,0.0005488674,0.0002691699,0.00032745942],"category_scores_gemma":[0.00013140471,0.0007041907,0.00094858615,0.00084221544,0.0013391646,0.00012629191,0.00017593309,0.0011665947,0.00014034312],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.027429124,0.0026319444,0.000033672684,0.0029791545,0.0040372694,0.0002343641,0.0127548445,0.00015299025,0.332524,0.00089718855,0.011787253,0.6045382],"study_design_scores_gemma":[0.005801973,0.039143905,0.21198797,0.020833706,0.002747969,0.00048534584,0.0035375427,0.00009365949,0.008980609,0.0009844562,0.70258486,0.002817989],"about_ca_topic_score_codex":0.00003397347,"about_ca_topic_score_gemma":0.00000899333,"teacher_disagreement_score":0.6907976,"about_ca_system_score_codex":0.00023726474,"about_ca_system_score_gemma":0.000922551,"threshold_uncertainty_score":0.9995409},"labels":[],"label_agreement":null},{"id":"W2121222036","doi":"10.1083/jcb.201303144","title":"The<i>Drosophila</i>effector caspase Dcp-1 regulates mitochondrial dynamics and autophagic flux via SesB","year":2014,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Simon Fraser University; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Cell biology; Mitochondrion; Effector; Flux (metallurgy); ATP–ADP translocase; BAG3; Apoptosis; Biochemistry; Inner mitochondrial membrane; Chemistry","score_opus":0.005016332222815114,"score_gpt":0.23788544174276133,"score_spread":0.23286910951994622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121222036","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917155,0.00432211,0.0005589116,0.0016461901,0.00090749667,0.00018901688,0.0000060511825,0.000014442848,0.00064031093],"genre_scores_gemma":[0.9963646,0.00082316285,0.00013269807,0.00069907994,0.0011029912,0.0000019600125,0.0000082147135,0.00001891443,0.00084837887],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987653,0.00038114292,0.00036923823,0.00010794752,0.00012567743,0.00025071838],"domain_scores_gemma":[0.99833775,0.00076108804,0.00033306694,0.0003033116,0.0001100433,0.00015475783],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005906724,0.00016348905,0.0003536961,0.000053793738,0.00019827457,0.000015396812,0.00021632746,0.00012985372,0.00007236412],"category_scores_gemma":[0.000101591075,0.0000779263,0.00013529889,0.00006897119,0.00035887802,0.00003687214,0.000044423112,0.0003284769,0.000026846461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022959344,0.00012280337,0.00032496432,0.000038207203,0.0002381097,0.00005126506,0.00021315413,0.000018002085,0.9808643,0.0010256409,0.0010247478,0.013782877],"study_design_scores_gemma":[0.01685764,0.011029754,0.02462392,0.00018881392,0.0019006933,0.004904062,0.00024465096,0.01794136,0.83054274,0.053273235,0.03780582,0.00068728544],"about_ca_topic_score_codex":0.0000115440935,"about_ca_topic_score_gemma":0.000006425609,"teacher_disagreement_score":0.15032153,"about_ca_system_score_codex":0.00004146204,"about_ca_system_score_gemma":0.00007031937,"threshold_uncertainty_score":0.3177742},"labels":[],"label_agreement":null},{"id":"W2122477201","doi":"10.1093/hmg/ddr077","title":"Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease","year":2011,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":178,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; University of British Columbia; Ottawa Hospital; Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"PINK1; Parkin; Mitophagy; Biology; Mitochondrion; Genetics; Ubiquitin ligase; Mutation; Cell biology; Parkinson's disease; Autophagy; Ubiquitin; Gene; Disease; Medicine","score_opus":0.02935624581871952,"score_gpt":0.26942455193310205,"score_spread":0.24006830611438254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122477201","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97547704,0.0007544903,0.02289429,0.000073541865,0.00012837425,0.0004417667,0.000008904068,0.000015228544,0.00020634543],"genre_scores_gemma":[0.99786144,0.000014107824,0.0013776753,0.00042347095,0.00009231755,0.00003951194,0.000110941786,0.000016202437,0.00006430618],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99922836,0.000040630264,0.00023626773,0.00018122102,0.00018716215,0.00012637682],"domain_scores_gemma":[0.999478,0.0000070724054,0.000054579115,0.00023840702,0.00009712357,0.00012485778],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000456267,0.00009740976,0.00014758851,0.00013275852,0.00002924569,0.0000067177457,0.000046760593,0.00005015681,0.00018927114],"category_scores_gemma":[0.000024506679,0.000100740406,0.00006939156,0.00011953917,0.00003823449,0.000020176303,0.000017641953,0.000048280584,0.000012967719],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002210057,0.0009784951,0.11476372,0.00008341044,0.00018155701,0.00017029977,0.0006294989,0.0011529991,0.8646265,0.010641688,0.0009310697,0.0036306782],"study_design_scores_gemma":[0.0016174827,0.00017279136,0.866768,0.00004508016,0.000077833916,8.9432e-7,0.00001071853,0.00028057426,0.12341631,0.006611008,0.00091316213,0.0000861337],"about_ca_topic_score_codex":0.000008984226,"about_ca_topic_score_gemma":0.0000065821528,"teacher_disagreement_score":0.75200427,"about_ca_system_score_codex":0.000030000985,"about_ca_system_score_gemma":0.000063749074,"threshold_uncertainty_score":0.41080746},"labels":[],"label_agreement":null},{"id":"W2122568309","doi":"10.1371/journal.pgen.1004273","title":"Folliculin Regulates Ampk-Dependent Autophagy and Metabolic Stress Survival","year":2014,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Myrovlytis Trust; National Institutes of Health; Terry Fox Foundation; Kidney Foundation of Canada; McGill University","keywords":"Folliculin; AMPK; Autophagy; Biology; Cell biology; Regulator; Signal transduction; Caenorhabditis elegans; Protein kinase A; Cancer research; Phosphorylation; Apoptosis; Genetics; Gene","score_opus":0.015464194159118197,"score_gpt":0.2534234595718487,"score_spread":0.2379592654127305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122568309","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98967934,0.008379832,0.000121524216,0.00021335439,0.00016428137,0.00024356888,0.00001905556,0.00009148268,0.0010875943],"genre_scores_gemma":[0.9963892,0.0011443397,0.0006821771,0.00036335038,0.00043085808,0.000016334583,0.000025548026,0.000038548358,0.0009096458],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988625,0.000068162684,0.00021349799,0.00028057004,0.00031948244,0.0002557793],"domain_scores_gemma":[0.9991729,0.000059001555,0.000061751474,0.00040088195,0.00007010183,0.0002353238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001076107,0.00017892357,0.0003412014,0.000059932936,0.00006796093,0.000027783264,0.00009683104,0.000100232035,0.00015794253],"category_scores_gemma":[0.00004117188,0.00015107595,0.00006997214,0.00008196092,0.000076499586,0.000025120878,0.000055492612,0.00010976435,0.000047417223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001063413,0.0044084084,0.20240843,0.001164755,0.00432247,0.00033946516,0.003290445,0.0005236145,0.5905759,0.018503247,0.000932271,0.1724676],"study_design_scores_gemma":[0.0023504766,0.0002651438,0.08814353,0.000059368685,0.00050081743,0.00001861699,0.00006799315,0.0063031833,0.89342594,0.0021169507,0.0064816615,0.00026632354],"about_ca_topic_score_codex":0.0000058865344,"about_ca_topic_score_gemma":0.0000075082835,"teacher_disagreement_score":0.30285004,"about_ca_system_score_codex":0.00001022132,"about_ca_system_score_gemma":0.000037697646,"threshold_uncertainty_score":0.61606985},"labels":[],"label_agreement":null},{"id":"W2122699281","doi":"10.1016/j.nbd.2010.11.003","title":"Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain","year":2010,"lang":"en","type":"article","venue":"Neurobiology of Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":158,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Research Council Canada; University of California, Irvine; Directorate for Biological Sciences; Universiteit Gent; Vlaamse regering; National Institutes of Health; Fonds Wetenschappelijk Onderzoek","keywords":"Caspase; Cleavage (geology); Neuroscience; Alzheimer's disease; Disease; Cell biology; Apoptosis; Proteolytic enzymes; Chemistry; Biology; Biochemistry; Medicine; Programmed cell death; Pathology; Enzyme","score_opus":0.013174120040076197,"score_gpt":0.2876300165707269,"score_spread":0.2744558965306507,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122699281","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99050236,0.000351806,0.000013596507,0.007411066,0.00013270049,0.0012002519,0.00027466263,0.000026473968,0.00008711218],"genre_scores_gemma":[0.99336785,0.000014574818,0.00003346094,0.006205509,0.0000808237,0.00012041364,0.0001223656,0.000021037456,0.000033949822],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99873567,0.00020296307,0.00034867527,0.00031512813,0.00015517526,0.00024238326],"domain_scores_gemma":[0.9985997,0.00025438637,0.00012501293,0.0006065437,0.000052504085,0.000361856],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019756146,0.00017180122,0.0003170797,0.0001151761,0.0000394811,0.00000406733,0.00023969002,0.00007448936,0.00012710488],"category_scores_gemma":[0.00045207073,0.00012374348,0.0001505257,0.00019563443,0.00028575546,0.00004135344,0.000041708758,0.00024157285,0.00002007342],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018597484,0.008224276,0.4581327,0.0006024083,0.0003465548,0.00079966785,0.0009268817,0.000037498976,0.45846647,0.002049068,0.04518282,0.0066341525],"study_design_scores_gemma":[0.0017947744,0.00068313617,0.96738625,0.00006079906,0.00029260456,0.000006769116,0.000042097447,0.000025742725,0.027708499,0.00055713544,0.0012849917,0.00015721032],"about_ca_topic_score_codex":0.000043609372,"about_ca_topic_score_gemma":0.000018480976,"teacher_disagreement_score":0.5092535,"about_ca_system_score_codex":0.0000054336824,"about_ca_system_score_gemma":0.00017320964,"threshold_uncertainty_score":0.50461125},"labels":[],"label_agreement":null},{"id":"W2123030411","doi":"10.1073/pnas.1423588112","title":"Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis","year":2015,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; Biology; Programmed cell death; Cell; Endocytic cycle; Homeostasis; T cell; Conditional gene knockout; Endocytosis; Phenotype; Immunology; Apoptosis; Gene; Immune system; Genetics","score_opus":0.05065401061818658,"score_gpt":0.3274117422304499,"score_spread":0.2767577316122633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2123030411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99307805,0.0006506489,0.000012489883,0.0021602376,0.00006283482,0.00036202,0.00006950293,0.000012752812,0.0035914623],"genre_scores_gemma":[0.99791646,0.000024534449,0.00097234413,0.00023085989,0.00015065614,0.000023860126,6.7580703e-7,0.000005684566,0.0006749298],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99820626,0.0000043602504,0.00030960506,0.00019983335,0.0011417747,0.00013815962],"domain_scores_gemma":[0.9986435,0.00005511993,0.00048184526,0.0000147572755,0.00072435004,0.00008040303],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006706081,0.000092641436,0.00021959578,0.00014095001,0.000116860836,0.000010076532,0.00042325625,0.00008300967,0.000038625127],"category_scores_gemma":[0.00038490188,0.00006222026,0.00016193083,0.00042877687,0.000556021,0.00022844209,0.00007929175,0.00010377147,0.0000011169808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015370388,0.001809361,0.03733888,0.0010943987,0.000409019,1.342475e-7,0.0027763431,0.00053739065,0.8819348,0.041341178,0.02921899,0.002002425],"study_design_scores_gemma":[0.001937911,0.00035632672,0.06792691,0.00013894329,0.00012268712,0.000012680081,0.002115726,0.0011747181,0.89711034,0.02837002,0.00062468566,0.00010906382],"about_ca_topic_score_codex":0.0000052716123,"about_ca_topic_score_gemma":4.2493138e-8,"teacher_disagreement_score":0.030588033,"about_ca_system_score_codex":0.000050310955,"about_ca_system_score_gemma":0.00015038406,"threshold_uncertainty_score":0.25372684},"labels":[],"label_agreement":null},{"id":"W2124220048","doi":"10.2174/15665240113139990060","title":"Profilin1 Sensitizes Pancreatic Cancer Cells to Irradiation by Inducing Apoptosis and Reducing Autophagy","year":2013,"lang":"en","type":"article","venue":"Current Molecular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pancreas Centre (Canada)","funders":"","keywords":"Autophagy; Apoptosis; Pancreatic cancer; Cancer research; Cancer cell; Chemistry; Irradiation; Cancer; Cell biology; Biology; Medicine; Internal medicine; Biochemistry; Physics","score_opus":0.013255653356613514,"score_gpt":0.2984052383928382,"score_spread":0.28514958503622473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124220048","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9751762,0.01814372,0.0008855566,0.003720755,0.000574948,0.0011806694,0.000009651036,0.00009275911,0.00021573852],"genre_scores_gemma":[0.9953235,0.0011966095,0.0003436991,0.0022120774,0.00038258705,0.0002318413,0.00008132995,0.000044702498,0.00018367376],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983732,0.00006984778,0.00035988385,0.0004608139,0.00038163905,0.00035461382],"domain_scores_gemma":[0.9988642,0.000048680977,0.000108215034,0.00033407626,0.00014561962,0.00049923855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015247258,0.00026279475,0.0004646617,0.00017506517,0.000084310006,0.000020169467,0.00006829214,0.00008300109,0.0004125745],"category_scores_gemma":[0.00011636045,0.00021083141,0.000056009474,0.00029533613,0.00009292582,0.00008451469,0.000036072288,0.00022254937,0.000053274678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030780266,0.00007466154,0.00029588968,0.00022041253,0.00009699308,0.00000923523,0.00085376215,0.000011514917,0.9282334,0.000037851773,0.010139568,0.05999593],"study_design_scores_gemma":[0.0025789817,0.00043514158,0.013345632,0.0017611977,0.0005198012,0.000017640661,0.0002765007,0.001656295,0.9766256,0.00016511462,0.0022618428,0.00035625894],"about_ca_topic_score_codex":0.00040967797,"about_ca_topic_score_gemma":4.68694e-7,"teacher_disagreement_score":0.059639674,"about_ca_system_score_codex":0.00009850136,"about_ca_system_score_gemma":0.000096349635,"threshold_uncertainty_score":0.8597455},"labels":[],"label_agreement":null},{"id":"W2125249450","doi":"10.1136/gut.2010.228908","title":"Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2","year":2011,"lang":"en","type":"article","venue":"Gut","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":183,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"ATG16L1; NOD2; Cytokine; Autophagy; TLR4; Immunology; Biology; TLR2; Inflammation; Immune system; Innate immune system; Genetics","score_opus":0.031045163766941313,"score_gpt":0.26394850063582714,"score_spread":0.23290333686888584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125249450","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99769336,0.00028518046,0.0000791055,0.00017092461,0.00007340364,0.0005098327,0.000045776178,0.00015761952,0.0009847882],"genre_scores_gemma":[0.9980588,0.00003989829,0.00012680488,0.00020927288,0.00009349834,0.000046617446,0.000054219407,0.000042319374,0.0013285846],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987654,0.000102252125,0.00030275353,0.0002656756,0.00030041466,0.0002634891],"domain_scores_gemma":[0.9989842,0.00006935816,0.00022487993,0.00032136528,0.00021044225,0.00018972112],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016988195,0.0001903419,0.00029728818,0.0001816077,0.000081824575,0.000006453873,0.0001018906,0.000118221345,0.00033618583],"category_scores_gemma":[0.00027057124,0.00016955432,0.00013872108,0.00024548973,0.00008056581,0.00015958144,0.000028363402,0.0001375978,0.000037566857],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.030241717,0.0030633376,0.24296033,0.00034315416,0.001533131,0.0015496989,0.0043024174,0.0000160429,0.7054656,0.0024109131,0.001450841,0.0066627744],"study_design_scores_gemma":[0.0014674522,0.00019108593,0.8528169,0.00015179795,0.00013025432,0.000004760618,0.000034367782,0.00022278364,0.14352813,0.0011617065,0.00014608365,0.00014469365],"about_ca_topic_score_codex":0.00007437034,"about_ca_topic_score_gemma":0.0000031780237,"teacher_disagreement_score":0.60985655,"about_ca_system_score_codex":0.00011190946,"about_ca_system_score_gemma":0.00029803917,"threshold_uncertainty_score":0.6914224},"labels":[],"label_agreement":null},{"id":"W2125461230","doi":"10.1016/j.pneurobio.2013.10.004","title":"Autophagy and apoptosis dysfunction in neurodegenerative disorders","year":2013,"lang":"en","type":"review","venue":"Progress in Neurobiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1054,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children; St. Boniface Hospital; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Cancerfonden; Manitoba Health Research Council","keywords":"Autophagy; Cell biology; Biology; Neurodegeneration; Programmed cell death; Neuroscience; Autophagosome; Lysosome; Huntington's disease; Apoptosis; Fragmentation (computing); Disease; Medicine; Pathology; Genetics; Biochemistry","score_opus":0.02992238659260979,"score_gpt":0.3360248634785428,"score_spread":0.30610247688593306,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125461230","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.020398082,0.9770104,0.0000021272185,0.00011675473,0.0004825267,0.0017883407,0.000011686222,0.000056554807,0.00013351173],"genre_scores_gemma":[0.0033627765,0.994794,0.00006263404,0.00021154678,0.000106514795,0.0011505411,0.00013996327,0.00006174779,0.00011025782],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977875,0.00046035222,0.0005696208,0.00071868964,0.00007043604,0.00039340087],"domain_scores_gemma":[0.999203,0.00014976568,0.00021078179,0.00032021065,0.000021328433,0.00009485919],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000111077796,0.00043522473,0.0015094207,0.0004609762,0.000031761814,0.000016608274,0.00013056354,0.00043257524,0.00008972659],"category_scores_gemma":[0.000042762644,0.00033193105,0.00016525373,0.00036367943,0.00028097478,0.00006048948,0.000099399585,0.0006523143,0.00003717326],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003494013,0.00022169322,0.0018616674,0.002841737,0.000057324956,0.000027924745,0.00003805204,3.3278084e-7,0.0000031472307,0.00014162969,0.00006945282,0.9947021],"study_design_scores_gemma":[0.0033097244,0.0015413552,0.007798417,0.0059653474,0.0006200855,0.0001938679,0.000018307368,0.0000727011,0.00008330634,0.00033009815,0.9791819,0.0008849257],"about_ca_topic_score_codex":0.000013748496,"about_ca_topic_score_gemma":0.00001228971,"teacher_disagreement_score":0.99381715,"about_ca_system_score_codex":0.000057035184,"about_ca_system_score_gemma":0.000118427604,"threshold_uncertainty_score":0.9999133},"labels":[],"label_agreement":null},{"id":"W2126387714","doi":"10.1038/emboj.2010.352","title":"Fis1, Bap31 and the kiss of death between mitochondria and endoplasmic reticulum","year":2011,"lang":"en","type":"letter","venue":"The EMBO Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Endoplasmic reticulum; Biology; Cell biology; Mitochondrion; KISS (TNC); FIS1; Biochemistry; mitochondrial fusion; Mitochondrial DNA","score_opus":0.0220360334029317,"score_gpt":0.2554939067865436,"score_spread":0.2334578733836119,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126387714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.67991835,0.012169126,0.00005799809,0.30238634,0.00057216285,0.00063813117,0.000047939768,0.000019514415,0.004190449],"genre_scores_gemma":[0.5765017,0.012405064,0.00044587636,0.37721437,0.022879409,0.00003859162,0.000062253435,0.00019767859,0.0102550145],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99843836,0.00030008878,0.00042031685,0.00018012204,0.00037305994,0.0002880669],"domain_scores_gemma":[0.99854153,0.00042360876,0.00040005866,0.00042887262,0.00008688636,0.00011901797],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005090092,0.00026533077,0.00065461127,0.00008637132,0.00020984132,0.000045249537,0.00028346447,0.0002549495,0.00033131966],"category_scores_gemma":[0.00006774022,0.00012065145,0.00020820428,0.000056206125,0.0005392713,0.00004538197,0.00007448966,0.002071735,0.000009885564],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010851908,0.000053395976,0.007516253,0.0003226974,0.0028320234,0.0011660451,0.0034568475,1.9880773e-7,0.00024357546,0.00046916475,0.9798806,0.0029740473],"study_design_scores_gemma":[0.026015604,0.0014918033,0.0890208,0.002820846,0.011228603,0.021010604,0.0005327266,0.000059717677,0.0073003075,0.081069544,0.7583509,0.0010985248],"about_ca_topic_score_codex":0.000028805167,"about_ca_topic_score_gemma":5.955515e-7,"teacher_disagreement_score":0.22152965,"about_ca_system_score_codex":0.00001608431,"about_ca_system_score_gemma":0.00011230678,"threshold_uncertainty_score":0.9000773},"labels":[],"label_agreement":null},{"id":"W2126932701","doi":"10.1194/jlr.m005702","title":"Autophagy plays a protective role in free cholesterol overload-induced death of smooth muscle cells","year":2010,"lang":"en","type":"article","venue":"Journal of Lipid Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Autophagy; Cell biology; Endoplasmic reticulum; Vacuole; Programmed cell death; Downregulation and upregulation; Mitochondrion; Organelle; Apoptosis; Chemistry; Unfolded protein response; Cell; Foam cell; Biology; Cholesterol; Cytoplasm; Biochemistry; Lipoprotein","score_opus":0.04301660965776552,"score_gpt":0.36393566206898664,"score_spread":0.3209190524112211,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126932701","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99550825,0.00035631907,0.000020214753,0.0009229772,0.00035037543,0.0005588027,0.00000988145,0.00000846963,0.002264691],"genre_scores_gemma":[0.99818134,0.00008024994,0.0003545843,0.00008039584,0.00093288434,0.000019324674,5.9819047e-7,0.000030191019,0.0003204473],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973609,0.00025629788,0.00057905895,0.00019008125,0.0011635444,0.00045013448],"domain_scores_gemma":[0.9980834,0.0001944789,0.00025660355,0.00049475755,0.00064836635,0.0003223817],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022494504,0.00013919009,0.00046044012,0.0006951726,0.000060226732,0.000025322859,0.00042835003,0.00021394226,0.0003629112],"category_scores_gemma":[0.0005109292,0.00010812356,0.0001897435,0.00042437433,0.00012464852,0.00020940743,0.00010151919,0.0021520918,0.000017991963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00093957584,0.0009938352,0.0021474566,0.00008499071,0.000077085875,0.00023350774,0.0009793211,0.000006166609,0.98508465,0.00014946712,0.00054653024,0.008757421],"study_design_scores_gemma":[0.00595761,0.002206099,0.3322761,0.00036850432,0.000023950559,0.000076703895,0.00040552107,0.00016382214,0.65252185,0.002527372,0.0033624866,0.000109952205],"about_ca_topic_score_codex":0.00021624684,"about_ca_topic_score_gemma":0.000038216556,"teacher_disagreement_score":0.33256277,"about_ca_system_score_codex":0.00011082356,"about_ca_system_score_gemma":0.0007425404,"threshold_uncertainty_score":0.93498874},"labels":[],"label_agreement":null},{"id":"W2127440157","doi":"10.1038/embor.2009.256","title":"Nix is a selective autophagy receptor for mitochondrial clearance","year":2009,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1265,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health; Terry Fox Foundation; Deutsche Forschungsgemeinschaft","keywords":"Autophagy; Cell biology; ULK1; Cytosol; Lysosome; Mitochondrion; Organelle; Biology; Receptor; Mitophagy; Ubiquitin; Biochemistry; Apoptosis; Enzyme; Gene","score_opus":0.01114472014403911,"score_gpt":0.2976898890821105,"score_spread":0.2865451689380714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127440157","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97850734,0.0013549333,0.0011351282,0.00340659,0.0017880234,0.0018638594,0.00001884381,0.00034697697,0.011578329],"genre_scores_gemma":[0.9767909,0.00004915357,0.00360298,0.006315577,0.0015870108,0.00009400183,0.00004231306,0.000035300713,0.01148273],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99865884,0.000016784588,0.00035438134,0.00042256474,0.00024764606,0.0002997896],"domain_scores_gemma":[0.9990547,0.000027833115,0.0001780904,0.00041037973,0.00015638478,0.00017264803],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001002845,0.00016902962,0.00033497886,0.000060556744,0.00009845953,0.000017549655,0.000047270656,0.00012494902,0.00047533424],"category_scores_gemma":[0.00012673918,0.00015038751,0.00023033477,0.0001618853,0.000032429565,0.00008344931,0.000006844697,0.00013007293,0.000043929533],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004718008,0.0015432597,0.0012736499,0.00012160431,0.0006167367,0.0021537635,0.0029646868,0.000009170276,0.2117474,0.0009715609,0.6976637,0.076216444],"study_design_scores_gemma":[0.004304475,0.0023612387,0.060239304,0.00019373797,0.00025683944,0.0010639472,0.00005984333,0.00016564698,0.4684899,0.016032651,0.44628423,0.0005481864],"about_ca_topic_score_codex":0.0000072256994,"about_ca_topic_score_gemma":4.960255e-7,"teacher_disagreement_score":0.2567425,"about_ca_system_score_codex":0.00006806401,"about_ca_system_score_gemma":0.00020186482,"threshold_uncertainty_score":0.6132625},"labels":[],"label_agreement":null},{"id":"W2129321855","doi":"10.1073/pnas.0810611105","title":"Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes","year":2008,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":528,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Autophagy; Ubiquitin; Cell biology; ATG12; Lysosome; Autophagosome; Cytosol; Cytoplasm; Biology; Protein degradation; Ubiquitin ligase; Ubiquitin-Protein Ligases; Phosphatidylinositol; F-box protein; Biochemistry; Kinase; ATG5; Enzyme; Apoptosis; Gene","score_opus":0.05576985694752111,"score_gpt":0.3185374061451257,"score_spread":0.2627675491976046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129321855","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954185,0.00060522335,0.0000010949263,0.0015455163,0.000004729415,0.00026655826,0.0000079333695,0.000009412934,0.0021410582],"genre_scores_gemma":[0.99826145,0.00017353064,0.0009415254,0.00025720833,0.000042678188,0.000010842314,1.7107287e-7,0.0000033244437,0.00030929144],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986437,0.000004791634,0.0002755078,0.00014912004,0.0008314048,0.00009550429],"domain_scores_gemma":[0.999328,0.000056552122,0.00033519254,0.0000070412925,0.00023449978,0.00003869025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046357806,0.00007208995,0.00018135572,0.00014501691,0.00012653893,0.0000040249765,0.0002049805,0.000056463407,0.000027985763],"category_scores_gemma":[0.0002484009,0.00004585312,0.000062317034,0.00042511392,0.0009728408,0.00023940978,0.0000437687,0.00008344461,5.071772e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000469014,0.00011332392,0.020165097,0.00014988099,0.000029793146,2.6893899e-8,0.00039740253,0.0000059817926,0.9631363,0.015333765,0.00013899407,0.00048250917],"study_design_scores_gemma":[0.0002923055,0.00011289831,0.25054303,0.00010524937,0.000015856938,0.000027920783,0.00008916911,0.0002478782,0.73853844,0.009964156,0.00002614577,0.000036950478],"about_ca_topic_score_codex":0.000004506768,"about_ca_topic_score_gemma":1.0197615e-8,"teacher_disagreement_score":0.23037793,"about_ca_system_score_codex":0.0000134318725,"about_ca_system_score_gemma":0.00006707743,"threshold_uncertainty_score":0.35844725},"labels":[],"label_agreement":null},{"id":"W2129527287","doi":"10.1124/dmd.109.028480","title":"Vacuolar ATPase-Mediated Cellular Concentration and Retention of Quinacrine: A Model for the Distribution of Lipophilic Cationic Drugs to Autophagic Vacuoles","year":2009,"lang":"en","type":"article","venue":"Drug Metabolism and Disposition","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Vacuole; Bafilomycin; Endosome; Biochemistry; ATPase; Biology; Phospholipidosis; Cytosol; Cytoplasm; Vesicle; Chemistry; Autophagy; Cell biology; Biophysics; Membrane; Cell; Enzyme","score_opus":0.008356026617297575,"score_gpt":0.24931377643192568,"score_spread":0.2409577498146281,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129527287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9667997,0.0074870377,0.023176827,0.0013236876,0.000053716678,0.00087101286,0.0002511415,0.000024258503,0.000012622123],"genre_scores_gemma":[0.9973673,0.0009878213,0.0001859727,0.00022856002,0.0000787013,0.000046024008,0.0010514566,0.0000083354635,0.00004581601],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99913627,0.00004055913,0.00030742868,0.0001965979,0.00018436949,0.00013478482],"domain_scores_gemma":[0.9993498,0.000055949335,0.00014471478,0.0001800573,0.0001743403,0.00009517797],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023171277,0.0001246773,0.00025236246,0.000038918657,0.000112521215,0.000014807176,0.00004412447,0.000056266646,0.000004337188],"category_scores_gemma":[0.000041024105,0.00009448174,0.00008292821,0.00016276533,0.000059612827,0.00015116179,0.000010028786,0.00005259364,6.483518e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027850403,0.00085714844,0.0005855005,0.00058354234,0.00022926865,0.000002658453,0.005816762,0.0006376448,0.8775806,0.068150766,0.00046493582,0.04230616],"study_design_scores_gemma":[0.006584316,0.00044066628,0.40341097,0.00026294775,0.0018773648,0.000009689259,0.0005204805,0.27520022,0.29628852,0.014695228,0.00036963986,0.00033996368],"about_ca_topic_score_codex":0.000026894679,"about_ca_topic_score_gemma":0.0000011781474,"teacher_disagreement_score":0.58129203,"about_ca_system_score_codex":0.000018413315,"about_ca_system_score_gemma":0.000045410277,"threshold_uncertainty_score":0.38528535},"labels":[],"label_agreement":null},{"id":"W2130129132","doi":"10.1111/j.1399-0004.2004.00347a.x","title":"HD aggregates accelerate autophagy","year":2004,"lang":"en","type":"article","venue":"Clinical Genetics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Library science; Citation; Columbia university; New england; Sociology; Media studies; Computer science; Political science; Law","score_opus":0.08259568182245988,"score_gpt":0.4223679942248837,"score_spread":0.3397723124024238,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130129132","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9880676,0.007130789,0.00037312508,0.0011789175,0.0005555195,0.00023515435,0.0000056534204,0.00012847385,0.0023247136],"genre_scores_gemma":[0.9819244,0.004926842,0.0042142766,0.006803775,0.00090205297,0.000009853965,0.000019360552,0.00003478886,0.0011646125],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.998685,0.000036124893,0.00051940867,0.00029941075,0.00019636424,0.00026371537],"domain_scores_gemma":[0.99892473,0.00009042583,0.00009563852,0.00045756338,0.00008721856,0.00034443394],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019553833,0.00014761073,0.00034179783,0.00003345365,0.000057125966,0.00001991582,0.00013825,0.00018824793,0.00036750987],"category_scores_gemma":[0.00014592038,0.00012188457,0.0002303537,0.00013002908,0.0001894446,0.00002414952,0.00004879324,0.00025211964,0.000642912],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016853533,0.0070190798,0.12424398,0.00030210507,0.0014959665,0.0024750624,0.00059309206,0.00079744123,0.009750781,0.0060390076,0.0060940883,0.83950406],"study_design_scores_gemma":[0.015874779,0.0031238163,0.7035912,0.000303738,0.00052416464,0.00011029627,0.00006640415,0.00039956468,0.1080897,0.043393243,0.12384844,0.0006746081],"about_ca_topic_score_codex":0.0000026463074,"about_ca_topic_score_gemma":0.000001278931,"teacher_disagreement_score":0.83882946,"about_ca_system_score_codex":0.000025521013,"about_ca_system_score_gemma":0.00023841934,"threshold_uncertainty_score":0.82635474},"labels":[],"label_agreement":null},{"id":"W2131396392","doi":"10.1183/13993003/erj.42.suppl_57.388","title":"Controlled mechanical ventilation in septic animals: Effects on diaphragm function","year":2013,"lang":"en","type":"article","venue":"European Respiratory Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Sepsis; Medicine; Diaphragm (acoustics); Mechanical ventilation; Autophagy; Lipopolysaccharide; Saline; Autophagosome; Internal medicine; Biology; Apoptosis; Biochemistry","score_opus":0.01564222098804826,"score_gpt":0.2647896433757122,"score_spread":0.24914742238766394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131396392","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923415,0.00093503227,0.00037979524,0.00015668494,0.00037971933,0.00053438067,3.365683e-7,0.0000488278,0.0052237157],"genre_scores_gemma":[0.99566984,0.000023798983,0.00003947579,0.0031421182,0.0008766289,0.000014948116,0.0000012581013,0.000041178704,0.00019076472],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981555,0.0006988482,0.00041931978,0.00018698403,0.00030834434,0.00023104178],"domain_scores_gemma":[0.99920815,0.00011093566,0.00017059859,0.00019203295,0.00007987933,0.00023839637],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00083920377,0.00015489692,0.00030258417,0.00022686673,0.00009741426,0.000064870364,0.00007889293,0.00004854475,0.000836232],"category_scores_gemma":[0.0001988645,0.00011728169,0.0001788398,0.00013036464,0.000019321264,0.00012343394,0.000015236771,0.00045642664,0.0010598697],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0229136,0.0018242213,0.029799683,0.00020074067,0.00088505854,0.0064680926,0.00044093488,0.00012249792,0.63240224,0.0015305713,0.01737506,0.2860373],"study_design_scores_gemma":[0.020571562,0.0027703573,0.96066874,0.00039360923,0.00013034003,0.00008399757,0.00003743369,0.00031280445,0.0055537242,0.00057779416,0.0087051075,0.00019452402],"about_ca_topic_score_codex":6.7983905e-7,"about_ca_topic_score_gemma":3.189783e-7,"teacher_disagreement_score":0.93086904,"about_ca_system_score_codex":0.000081086735,"about_ca_system_score_gemma":0.00005231685,"threshold_uncertainty_score":0.9997179},"labels":[],"label_agreement":null},{"id":"W2131439006","doi":"10.1186/ar3778","title":"TNFα modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts","year":2012,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":103,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital; Canada Research Chairs; Discovery Centre; University Health Network","funders":"Pfizer Canada; Pfizer","keywords":"Rheumatology; Rheumatoid arthritis; Medicine; Tumor necrosis factor alpha; Inflammation; Internal medicine; Synovial membrane; Immunology; Cancer research","score_opus":0.049052927206124954,"score_gpt":0.32558969427563395,"score_spread":0.27653676706950897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131439006","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9520293,0.044115722,0.000062296414,0.00071936817,0.00012167288,0.0018075603,0.000025477015,0.0001401598,0.0009784778],"genre_scores_gemma":[0.9480662,0.049875353,0.00046241967,0.00019610576,0.00036544268,0.00055984675,0.00009519958,0.00007712541,0.00030233228],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99610555,0.00051175535,0.00052391493,0.00045848652,0.0010957796,0.0013045126],"domain_scores_gemma":[0.9983996,0.00016820055,0.00007382655,0.00060262694,0.00024200646,0.00051372894],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015289428,0.00028459157,0.00047109157,0.0004973371,0.00026714968,0.00008805191,0.00021574588,0.00021338984,0.0012361124],"category_scores_gemma":[0.00019200826,0.00026716135,0.00015753656,0.0007508519,0.00028740318,0.0006431911,0.000067577435,0.00068860664,0.00046671124],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013529217,0.0016755271,0.017591411,0.0000381442,0.00010456946,0.00022850455,0.0018726491,0.000004347373,0.2131802,0.003674655,0.0012367892,0.7590403],"study_design_scores_gemma":[0.03437299,0.005159793,0.19925566,0.005396111,0.000004633959,0.00052615645,0.0014210683,0.00072736223,0.656745,0.01959188,0.07532755,0.0014717582],"about_ca_topic_score_codex":0.00029563557,"about_ca_topic_score_gemma":0.00010322894,"teacher_disagreement_score":0.75756854,"about_ca_system_score_codex":0.0001590149,"about_ca_system_score_gemma":0.00027125108,"threshold_uncertainty_score":0.99997807},"labels":[],"label_agreement":null},{"id":"W2131936131","doi":"10.1038/emboj.2010.327","title":"MCL‐1 is a stress sensor that regulates autophagy in a developmentally regulated manner","year":2010,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":179,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Biology; Cell biology; Apoptosis; Regulator; Programmed cell death; Transgene; Downregulation and upregulation; Cell fate determination; BAG3; Transcription factor; Gene; Genetics","score_opus":0.01372727748108639,"score_gpt":0.26985830886839307,"score_spread":0.2561310313873067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131936131","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933851,0.0004501874,0.0000094754005,0.0039573284,0.0004480312,0.00022147149,0.0000065205422,0.00004637217,0.0014755147],"genre_scores_gemma":[0.99184537,0.000110536115,0.000642797,0.0019842396,0.00036694884,0.0000070045003,0.0000069955527,0.000035695695,0.005000434],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99862784,0.00007450466,0.00033265815,0.00018587064,0.0003925546,0.00038655676],"domain_scores_gemma":[0.999145,0.000053842756,0.00014741952,0.0003559247,0.00008238579,0.00021545183],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00043877005,0.00019883916,0.00027569404,0.00014925875,0.00020531865,0.00006870937,0.00024571503,0.00011186252,0.0024571011],"category_scores_gemma":[0.000032090313,0.00012083546,0.00013136645,0.00019594596,0.00012674843,0.000121499485,0.00004600529,0.0008345134,0.00008722205],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0057791346,0.0029290125,0.17801668,0.00024677653,0.0030087775,0.009757165,0.036002483,0.00012815936,0.64206797,0.0030339921,0.040141318,0.07888856],"study_design_scores_gemma":[0.004799651,0.00013854529,0.6454396,0.00034151674,0.00013362626,0.00564881,0.0010323279,0.00060676964,0.32949996,0.0057213902,0.006293878,0.00034388236],"about_ca_topic_score_codex":0.000017256314,"about_ca_topic_score_gemma":0.000019811476,"teacher_disagreement_score":0.46742296,"about_ca_system_score_codex":0.00005705094,"about_ca_system_score_gemma":0.00020858849,"threshold_uncertainty_score":0.9984548},"labels":[],"label_agreement":null},{"id":"W2132434264","doi":"10.1111/j.1471-4159.2009.06507.x","title":"Nerve growth factor activation of the TrkA receptor induces cell death, by macropinocytosis, in medulloblastoma Daoy cells","year":2009,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Robarts Clinical Trials","funders":"Krembil Foundation; Cancer Research Society","keywords":"Cell biology; Nerve growth factor; Biology; Programmed cell death; Tropomyosin receptor kinase A; Autophagy; Low-affinity nerve growth factor receptor; Apoptosis; Receptor; Biochemistry","score_opus":0.010580252764889428,"score_gpt":0.2486825230682135,"score_spread":0.2381022703033241,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132434264","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982904,0.0002803634,0.0000118607495,0.0008381345,0.00011816143,0.00008661041,0.000012851655,0.0000060179127,0.00035559118],"genre_scores_gemma":[0.9987958,0.00021530355,0.000075994845,0.00054066075,0.00017412189,8.187883e-7,0.0000030317904,0.000012411568,0.00018183753],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988781,0.00004215557,0.00044836305,0.00012308522,0.00036098002,0.0001472752],"domain_scores_gemma":[0.99901366,0.00005325662,0.0005097125,0.00017829065,0.00013054047,0.00011451181],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006072094,0.00014119915,0.0002789235,0.000050059094,0.000027050475,0.000010250425,0.00022964315,0.00011132907,0.00008248838],"category_scores_gemma":[0.000068069436,0.00009747726,0.00017611736,0.00017544311,0.00003203489,0.000096811906,0.000016256863,0.00040836487,0.0000013241993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002866689,0.00039873514,0.0016714328,0.000064034,0.000021021915,0.000021492768,0.000118483156,0.0000025318864,0.9949127,0.0000011972728,0.0019858573,0.00051588326],"study_design_scores_gemma":[0.0013132661,0.00025838142,0.04483872,0.00018655941,0.00003115222,0.00004215708,0.00006286695,0.0000048017337,0.9529048,0.000053956366,0.0002312588,0.00007204271],"about_ca_topic_score_codex":0.0000032472158,"about_ca_topic_score_gemma":4.1723176e-8,"teacher_disagreement_score":0.043167286,"about_ca_system_score_codex":0.00006375741,"about_ca_system_score_gemma":0.00014244477,"threshold_uncertainty_score":0.39750075},"labels":[],"label_agreement":null},{"id":"W2132763961","doi":"10.1016/j.cell.2010.04.009","title":"Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation","year":2010,"lang":"en","type":"article","venue":"Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1370,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"National Institutes of Health","keywords":"Autophagosome; Autophagy; Cell biology; Biology; Mitochondrion; Cytosol; FIS1; Organelle; ATG5; Bacterial outer membrane; Organelle biogenesis; Biogenesis; Mitophagy; Biochemistry; mitochondrial fusion; Apoptosis; Mitochondrial DNA","score_opus":0.008950544386628819,"score_gpt":0.2499474673475071,"score_spread":0.2409969229608783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132763961","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997205,0.0005216374,0.00006860792,0.0003103282,0.00059650914,0.0004916645,0.00003728409,0.000103397346,0.0006655258],"genre_scores_gemma":[0.99203944,0.00008011602,0.0017162713,0.0002732078,0.0005806144,0.00008177238,0.0001002039,0.00003207025,0.005096284],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99933887,0.0000069887446,0.00015041247,0.00019608441,0.00011496114,0.00019269102],"domain_scores_gemma":[0.99945897,0.000038608854,0.00004867985,0.0002698047,0.00006670426,0.00011725628],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004829596,0.00011221658,0.00015468938,0.000076652876,0.000088443645,0.000014777288,0.0000718019,0.00009578697,0.00065782823],"category_scores_gemma":[0.000021737585,0.000098694,0.000115509094,0.00008635703,0.000031872878,0.00007053085,0.000010486565,0.00008252332,0.000085261934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019771796,0.00012322942,0.0018933669,0.00028752396,0.00002666723,0.000011997321,0.000120493096,0.0000014579583,0.9963115,0.00007135733,0.00054854463,0.00040612978],"study_design_scores_gemma":[0.0021153423,0.00007079509,0.03735991,0.000012376754,0.00007092742,0.000008172554,0.000028338924,0.000117647,0.94269377,0.00033237354,0.017081128,0.00010919684],"about_ca_topic_score_codex":0.000010868055,"about_ca_topic_score_gemma":0.0000042701436,"teacher_disagreement_score":0.053617723,"about_ca_system_score_codex":0.000013320825,"about_ca_system_score_gemma":0.00005860781,"threshold_uncertainty_score":0.7202758},"labels":[],"label_agreement":null},{"id":"W2132876189","doi":"10.1242/bio.20122840","title":"The bacterial and cellular determinants controlling the recruitment of mTOR to the <i>Salmonella</i>-containing vacuole","year":2012,"lang":"en","type":"article","venue":"Biology Open","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Burroughs Wellcome Fund","keywords":"Autophagy; Vacuole; Salmonella; PI3K/AKT/mTOR pathway; Biology; Starvation; Cytosol; Microbiology; Bacteria; Cell biology; Signal transduction; Apoptosis; Biochemistry; Genetics; Enzyme","score_opus":0.07021283346991657,"score_gpt":0.3537908853516784,"score_spread":0.28357805188176183,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132876189","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99173915,0.0037950412,0.000030233174,0.0017175082,0.0004697925,0.0016037748,0.000010941293,0.000006377617,0.00062720134],"genre_scores_gemma":[0.99763244,0.00015721476,0.00004864861,0.0012199864,0.00042849145,0.00019306,0.0000055855735,0.000009892774,0.0003046769],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99918693,0.00018511598,0.00020131504,0.00012214447,0.000053482378,0.0002509836],"domain_scores_gemma":[0.999161,0.0002985861,0.00009644071,0.00033443398,0.000028321045,0.00008122514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009226884,0.0000975693,0.00022681034,0.000010583935,0.00026225206,0.000025402365,0.0003188076,0.00005766552,0.00004086026],"category_scores_gemma":[0.00006854715,0.000038479666,0.00004482417,0.000040222523,0.00012479306,0.000035447243,0.00018855376,0.000077981575,0.000016395668],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012941431,0.00043533745,0.22986323,0.000037697595,0.0012959553,0.000023365743,0.007710156,0.0000029088824,0.5397748,0.009574512,0.002837704,0.19550289],"study_design_scores_gemma":[0.0052753272,0.0014608642,0.089247316,0.00009212046,0.00033000094,0.000039051603,0.001485393,0.00010952538,0.15791218,0.0004438009,0.7433728,0.00023160505],"about_ca_topic_score_codex":0.00008660941,"about_ca_topic_score_gemma":0.000013581534,"teacher_disagreement_score":0.74053514,"about_ca_system_score_codex":0.000010989507,"about_ca_system_score_gemma":0.000055118107,"threshold_uncertainty_score":0.20170574},"labels":[],"label_agreement":null},{"id":"W2134156907","doi":"10.1242/jcs.150961","title":"Proteasome dysfunction induces muscle growth defects and protein aggregation","year":2014,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center of Neurology and Psychiatry; York University","keywords":"Autophagy; Biology; Proteasome; Cell biology; Lysosome; Myocyte; Ubiquitin; Organelle; Sarcomere; Autophagosome; Protein degradation; Biochemistry; Gene; Apoptosis; Enzyme","score_opus":0.007901086918855953,"score_gpt":0.2351667688518696,"score_spread":0.22726568193301364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134156907","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99704605,0.00020318256,0.000603869,0.00025753808,0.00010223918,0.00018162046,9.9118665e-8,0.000007422687,0.0015979593],"genre_scores_gemma":[0.9987671,0.000026922113,0.00073081313,0.00015153734,0.00017187753,0.0000028459913,1.05446404e-7,0.000003970316,0.00014482588],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919516,0.000028784652,0.00015423079,0.0000984696,0.00040746032,0.00011589192],"domain_scores_gemma":[0.99932134,0.000017875844,0.00021202571,0.00007552519,0.00021222528,0.00016098299],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000754721,0.00005598913,0.000107031534,0.00013820872,0.00010428955,0.000036149264,0.00007793161,0.000027667384,0.000017797085],"category_scores_gemma":[0.00020840381,0.000038698403,0.00003243899,0.00025596796,0.00015163675,0.0003901828,0.000013202446,0.000115643415,0.000004948543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005595579,0.00007255493,0.0012330174,0.000039143255,0.000002675481,0.0000074608874,0.00014505221,0.0000015670895,0.98821855,0.00022286718,0.000025829606,0.00997531],"study_design_scores_gemma":[0.0010445488,0.00090488617,0.1150789,0.00016043129,0.00002534683,0.000062471925,0.00005072163,0.00018840759,0.8789542,0.00300426,0.00046398747,0.00006189408],"about_ca_topic_score_codex":0.0000026163627,"about_ca_topic_score_gemma":2.088055e-7,"teacher_disagreement_score":0.11384588,"about_ca_system_score_codex":0.00003391027,"about_ca_system_score_gemma":0.00016121315,"threshold_uncertainty_score":0.15780751},"labels":[],"label_agreement":null},{"id":"W2134810582","doi":"10.1186/s13048-015-0182-y","title":"Beclin-1 expression is retained in high-grade serous ovarian cancer yet is not essential for autophagy induction in vitro","year":2015,"lang":"en","type":"article","venue":"Journal of Ovarian Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ovarian Cancer Canada; Western University","funders":"Canadian Institutes of Health Research; London Health Sciences Centre","keywords":"BECN1; Autophagy; Gene knockdown; Ovarian cancer; Biology; Cancer research; Carcinogenesis; Cell biology; Cancer; Cell culture; Apoptosis; Genetics","score_opus":0.1299015093640004,"score_gpt":0.4371915109531292,"score_spread":0.3072900015891288,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134810582","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9825929,0.0007160677,0.00036010993,0.014806155,0.0006843555,0.00066344294,0.0000413763,0.000012066319,0.00012353867],"genre_scores_gemma":[0.99430746,0.00021618287,0.0023471043,0.00074265886,0.0012966822,0.00004664473,0.000013302932,0.000043495904,0.000986448],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966442,0.000371092,0.0007977758,0.00031674787,0.0012910628,0.0005791068],"domain_scores_gemma":[0.99802697,0.00018893262,0.00027037505,0.000340522,0.00073155446,0.00044163532],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0030914247,0.00018009642,0.00055947533,0.0010070995,0.00008930182,0.000060779814,0.0002830981,0.00029427718,0.0004378839],"category_scores_gemma":[0.0004455516,0.00014802458,0.00016034003,0.0007519487,0.000095484625,0.00032491694,0.00006985709,0.0011417735,0.000009981499],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.038073882,0.0019325719,0.0031624555,0.00024792505,0.00031924288,0.0018934302,0.008622591,0.00007514962,0.88647884,0.0003961898,0.041919913,0.016877819],"study_design_scores_gemma":[0.02472421,0.0011899854,0.032749247,0.0006401791,0.000072276576,0.00017753478,0.0015238252,0.0015864912,0.9270726,0.0062601836,0.0037651018,0.00023835333],"about_ca_topic_score_codex":0.0008127893,"about_ca_topic_score_gemma":0.000028540271,"teacher_disagreement_score":0.040593784,"about_ca_system_score_codex":0.0004448364,"about_ca_system_score_gemma":0.0015958347,"threshold_uncertainty_score":0.6036267},"labels":[],"label_agreement":null},{"id":"W2135414511","doi":"10.1242/jcs.011163","title":"Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species","year":2007,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":446,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; University of Manitoba","funders":"","keywords":"Autophagy; ATG5; Programmed cell death; Rotenone; Biology; Reactive oxygen species; HeLa; Cell biology; Mitochondrial ROS; Apoptosis; Mitochondrion; Cell culture; Molecular biology; Cell; Biochemistry","score_opus":0.010282093557138007,"score_gpt":0.25770691597099427,"score_spread":0.24742482241385627,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135414511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948479,0.0015549323,0.00020591686,0.00016308416,0.0002821411,0.00016687284,0.000009126435,0.000009470998,0.00276057],"genre_scores_gemma":[0.9981213,0.00025234817,0.00074755563,0.00013929914,0.00026597668,4.6366702e-7,0.0000034944037,0.000010902564,0.00045866458],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979919,0.00002532539,0.00056285126,0.00020208013,0.00085760566,0.00036019398],"domain_scores_gemma":[0.99853355,0.000118926684,0.0005489736,0.00014392496,0.0002874649,0.00036714596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000827689,0.0001554171,0.0003768854,0.00028835167,0.0001652776,0.000013039965,0.00022843193,0.00007804753,0.000053077325],"category_scores_gemma":[0.00006207571,0.00011762059,0.000104126164,0.0004993056,0.0004901133,0.0002738377,0.000026651787,0.00031383094,0.000001283714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004265873,0.00033514426,0.0021342032,0.000020991072,0.000019214725,0.000079432444,0.0010855652,0.0000020429256,0.9953789,0.00005155983,0.00036254025,0.00010379491],"study_design_scores_gemma":[0.0017708493,0.0011411288,0.047348414,0.00005652288,0.00006435666,0.00005943717,0.00034083315,0.000014842101,0.94737935,0.00019994182,0.001517941,0.00010638524],"about_ca_topic_score_codex":0.00002080978,"about_ca_topic_score_gemma":0.0000030071412,"teacher_disagreement_score":0.047999576,"about_ca_system_score_codex":0.00010466475,"about_ca_system_score_gemma":0.00048674204,"threshold_uncertainty_score":0.47964287},"labels":[],"label_agreement":null},{"id":"W2136000647","doi":"10.1093/hmg/ddn292","title":"Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease","year":2008,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":348,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Neurological Disorders and Stroke; Institut National de la Santé et de la Recherche Médicale; York University","keywords":"Autophagy; Lysosome; Biology; Skeletal muscle; Cell biology; Glycogen storage disease type II; Glycogen; Myocyte; Ubiquitin; ATG16L1; Biochemistry; Endocrinology; Enzyme replacement therapy; Internal medicine; Enzyme; Disease; Gene; Medicine; Apoptosis","score_opus":0.01993376988578649,"score_gpt":0.2868402945148623,"score_spread":0.2669065246290758,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136000647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997565,0.0015222594,0.00011320923,0.000040835515,0.000016005191,0.00064433116,0.000014393037,0.000008720198,0.00007527485],"genre_scores_gemma":[0.9996104,0.00011709151,0.00009391915,0.00006340904,0.000014220627,0.000018951167,0.000048668506,0.000020912097,0.000012421625],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99895716,0.00013586138,0.00033451768,0.00019936533,0.00019975734,0.00017335085],"domain_scores_gemma":[0.999462,0.000016401931,0.00010331232,0.00030618574,0.000042304022,0.00006980235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011747923,0.00013278791,0.00022299733,0.00017083662,0.000035010726,0.000004172067,0.00010097458,0.00007369553,0.0000398979],"category_scores_gemma":[0.000025634909,0.00010571486,0.00006635563,0.00021427254,0.00015279085,0.000037107602,0.00006384762,0.00013653627,4.251399e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014425983,0.0006099904,0.025846437,0.00009727443,0.00001889748,0.00031947548,0.0019837988,0.004512084,0.96385294,0.00012140854,0.0000032381656,0.002490218],"study_design_scores_gemma":[0.002215854,0.00014338185,0.8878374,0.00011066985,0.000016342228,0.0000022689214,0.00018421878,0.0058635455,0.10237001,0.0011486398,0.000023196617,0.00008448513],"about_ca_topic_score_codex":0.0001251686,"about_ca_topic_score_gemma":0.000047112455,"teacher_disagreement_score":0.8619909,"about_ca_system_score_codex":0.000028073038,"about_ca_system_score_gemma":0.000089040084,"threshold_uncertainty_score":0.4310927},"labels":[],"label_agreement":null},{"id":"W2137443599","doi":"10.1371/journal.pone.0069620","title":"Erythropoietin Protects Epithelial Cells from Excessive Autophagy and Apoptosis in Experimental Neonatal Necrotizing Enterocolitis","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Institute of Child Health and Human Development; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Autophagy; Necrotizing enterocolitis; Apoptosis; PI3K/AKT/mTOR pathway; Intestinal epithelium; Gastrointestinal epithelium; Biology; TUNEL assay; Pathogenesis; Protein kinase B; Immunology; Cancer research; Cell biology; Medicine; Gastrointestinal tract; Epithelium; Pathology; Internal medicine; Biochemistry","score_opus":0.01952100111541961,"score_gpt":0.23747506035574514,"score_spread":0.21795405924032554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137443599","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961523,0.0013341301,0.00001879012,0.000316989,0.000057862864,0.0017996999,0.000036542067,0.000077324046,0.00020637407],"genre_scores_gemma":[0.9964468,0.00010025637,0.0016979238,0.0005093938,0.00025910654,0.0006904696,0.000032625,0.000038542632,0.00022488405],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986766,0.000057484016,0.0002654286,0.00037266273,0.00030248665,0.00032533784],"domain_scores_gemma":[0.999384,0.000049496553,0.000082031256,0.00022673469,0.00004289908,0.00021486157],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000041653868,0.00020651553,0.00040016498,0.000093415794,0.00006800638,0.000046877376,0.000073180476,0.00011082135,0.0018648732],"category_scores_gemma":[0.000021564687,0.00019445209,0.000058935686,0.000089006884,0.000109650355,0.00019807667,0.00008040421,0.00020735832,0.00019901164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018571629,0.0014895892,0.0015790426,0.000082041086,0.00019030448,0.000081056794,0.0019783573,1.9828067e-7,0.9922623,0.000015281208,0.00005651815,0.0020795867],"study_design_scores_gemma":[0.003169001,0.00033970407,0.019572228,0.00040477145,0.000052132473,0.0000045050483,0.0006784584,0.00021757119,0.9750705,0.00028235855,0.000029841694,0.00017895368],"about_ca_topic_score_codex":0.0010139635,"about_ca_topic_score_gemma":0.0000069700227,"teacher_disagreement_score":0.017993186,"about_ca_system_score_codex":0.000077240446,"about_ca_system_score_gemma":0.00004151072,"threshold_uncertainty_score":0.9990476},"labels":[],"label_agreement":null},{"id":"W2137523482","doi":"10.1016/j.jtcvs.2013.04.042","title":"Autophagy gene fingerprint in human ischemia and reperfusion","year":2013,"lang":"en","type":"article","venue":"Journal of Thoracic and Cardiovascular Surgery","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; University of Toronto; Physicians' Services Incorporated Foundation; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Cell biology; Heat shock protein; Hsp70; Medicine; Downregulation and upregulation; Reperfusion injury; Biology; Ischemia; Gene; Cancer research; Apoptosis; Genetics; Internal medicine","score_opus":0.013241522574315304,"score_gpt":0.27451808442722053,"score_spread":0.2612765618529052,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137523482","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9439749,0.05530979,0.00017359229,0.00012913722,0.00010819676,0.00011253322,4.2289545e-7,0.0000092739865,0.00018214944],"genre_scores_gemma":[0.9935204,0.0056608687,0.0002989706,0.00016883328,0.00024054095,0.0000052150044,0.0000015831713,0.000016430313,0.00008717617],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9987959,0.00010176626,0.00043438136,0.00016538598,0.0003308729,0.00017167281],"domain_scores_gemma":[0.9992404,0.00006741198,0.00012706517,0.0002548921,0.00011355153,0.00019667785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011972638,0.00013128654,0.0006657114,0.00021396026,0.00005549199,0.000030272862,0.000040587885,0.00010078832,0.00009803967],"category_scores_gemma":[0.0000784923,0.00010098195,0.00057664135,0.000111812646,0.000059691454,0.00016325313,0.00003985603,0.00023923111,0.000003176778],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034580354,0.00027690467,0.12317928,0.00046838052,0.0024585668,0.003113807,0.0005635065,0.00004247266,0.12813151,0.000024072524,0.0016266576,0.73976904],"study_design_scores_gemma":[0.0013883638,0.00017718595,0.76894873,0.00093140436,0.00084731856,0.005041042,0.00029394604,0.0001454572,0.21704145,0.000823405,0.003966968,0.0003947508],"about_ca_topic_score_codex":0.00004245473,"about_ca_topic_score_gemma":2.5047694e-7,"teacher_disagreement_score":0.7393743,"about_ca_system_score_codex":0.000026123062,"about_ca_system_score_gemma":0.00007183676,"threshold_uncertainty_score":0.41179246},"labels":[],"label_agreement":null},{"id":"W2138125300","doi":"10.1371/journal.pone.0047265","title":"Autophagy and Skeletal Muscles in Sepsis","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal; McGill University Health Centre","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Autophagy; Mitochondrial biogenesis; Autophagosome; Cell biology; Skeletal muscle; Mitochondrion; Biology; Lysosome; ATG12; Internal medicine; Endocrinology; Biochemistry; ATG5; Medicine; Apoptosis","score_opus":0.04292398676450074,"score_gpt":0.2659781733916264,"score_spread":0.22305418662712564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138125300","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992965,0.0039410135,0.000002645319,0.00032764798,0.000020314437,0.00015570907,0.0000031621173,0.000044979774,0.0025395548],"genre_scores_gemma":[0.9977411,0.00027543682,0.0005808474,0.00061738584,0.00019406601,0.00001894435,0.0000070840074,0.000013562627,0.0005515708],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99944615,0.000017348075,0.00010046685,0.00009500935,0.00014324854,0.00019776254],"domain_scores_gemma":[0.9996692,0.000027473958,0.000019139625,0.00012976117,0.000013230881,0.00014120672],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007484399,0.00007305029,0.00017560023,0.000062314924,0.000020122525,0.0000045251263,0.000025263667,0.000049205264,0.000402923],"category_scores_gemma":[0.000029778008,0.00006428468,0.000026069823,0.000075886615,0.000036516918,0.0000853056,0.000017929919,0.00008664331,0.00007386664],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025013808,0.013189322,0.73021126,0.0006595871,0.0008965323,0.0001342692,0.0030968136,2.3534335e-7,0.2191522,0.0022825552,0.00044819678,0.029678874],"study_design_scores_gemma":[0.0013631093,0.00010655048,0.93452877,0.00014912427,0.00014672759,0.0000057630477,0.00006944762,0.000086826105,0.062769,0.0002586233,0.00041074524,0.00010532572],"about_ca_topic_score_codex":0.000013238524,"about_ca_topic_score_gemma":0.0000018013607,"teacher_disagreement_score":0.20431748,"about_ca_system_score_codex":0.000018607068,"about_ca_system_score_gemma":0.0000152224975,"threshold_uncertainty_score":0.44117245},"labels":[],"label_agreement":null},{"id":"W2138544728","doi":"10.1371/journal.pone.0007124","title":"Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling","year":2009,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":345,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Cancer Society Research Institute","keywords":"mTORC1; Autophagy; PI3K/AKT/mTOR pathway; Cell biology; Niclosamide; Rottlerin; Mechanistic target of rapamycin; Biology; Chemistry; Signal transduction; Biochemistry; Pharmacology; Apoptosis; Protein kinase C","score_opus":0.05433651801908413,"score_gpt":0.2789723222985533,"score_spread":0.22463580427946916,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138544728","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99714935,0.0010311827,0.00074365945,0.00018492957,0.000016568143,0.0005970201,0.000039175462,0.00004643282,0.00019166371],"genre_scores_gemma":[0.99457705,0.000021654185,0.0045367274,0.0004512703,0.00022609324,0.000014746744,0.000027001406,0.000024556037,0.00012087921],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987917,0.000012503292,0.00043164444,0.00019789072,0.00036064026,0.00020560555],"domain_scores_gemma":[0.9991585,0.00008675908,0.00018255778,0.00028552095,0.00017401372,0.00011265177],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015371238,0.00014209568,0.00053596514,0.000089680645,0.000021933958,0.0000029735909,0.00010204843,0.00011896504,0.000063602805],"category_scores_gemma":[0.00007098434,0.00012626294,0.00017957181,0.00015535086,0.000065232656,0.000047259266,0.000010906948,0.0000931883,0.0000022106883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041455022,0.0026474665,0.00073032413,0.0002115766,0.00045759437,0.000001387926,0.0001636268,0.000005633221,0.99262685,0.0011881973,0.000026393413,0.0015264178],"study_design_scores_gemma":[0.002141363,0.00061138696,0.0051590228,0.0005043278,0.00043045287,0.0000011768024,0.000022546572,0.00056546053,0.98822486,0.0022202483,0.000008956206,0.00011022008],"about_ca_topic_score_codex":0.0000056592667,"about_ca_topic_score_gemma":5.2684573e-8,"teacher_disagreement_score":0.0044286987,"about_ca_system_score_codex":0.000030571635,"about_ca_system_score_gemma":0.000057356225,"threshold_uncertainty_score":0.51488537},"labels":[],"label_agreement":null},{"id":"W2139128868","doi":"10.1242/jcs.114041","title":"Misregulation of autophagy and protein degradation systems in myopathies and muscular dystrophies","year":2013,"lang":"en","type":"review","venue":"Journal of Cell Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":176,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Autophagy; Biology; Ubiquitin; Proteasome; Cell biology; Lysosome; Wasting; Protein degradation; Muscle disorder; Myocyte; Skeletal muscle; Muscle weakness; Biochemistry; Anatomy; Internal medicine; Medicine; Enzyme","score_opus":0.024789970785629847,"score_gpt":0.30631321715217497,"score_spread":0.28152324636654513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139128868","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.17360003,0.82572067,0.000043964308,0.000010601309,0.000077613455,0.0004957733,0.0000010994378,0.0000022375941,0.000047981008],"genre_scores_gemma":[0.048873242,0.9503906,0.00047624513,0.0000031746372,0.000071589566,0.000009658197,0.0000010456733,0.000008625887,0.00016582181],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985527,0.0000802426,0.00064641784,0.00014581016,0.0004527839,0.00012207202],"domain_scores_gemma":[0.9986482,0.000039124992,0.00087957835,0.00012861037,0.00019116116,0.000113271286],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082571484,0.00013933946,0.0008169965,0.00052481674,0.00004152414,0.000044418164,0.000112975875,0.00008966513,0.000006149754],"category_scores_gemma":[0.00007482019,0.000089447276,0.00008666662,0.000392978,0.0003157377,0.00028993035,0.000024984314,0.00017067797,7.2931886e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053878244,0.00024468682,0.000112152404,0.04874657,0.00008480727,0.00015098906,0.00048471597,0.00001699613,0.027235944,0.0005385407,0.000034063345,0.92229664],"study_design_scores_gemma":[0.01213719,0.007908708,0.032536518,0.38358757,0.005804791,0.0074613425,0.002260123,0.0049361484,0.03747208,0.0022841985,0.5009895,0.002621837],"about_ca_topic_score_codex":0.000016060843,"about_ca_topic_score_gemma":2.9080508e-7,"teacher_disagreement_score":0.9196748,"about_ca_system_score_codex":0.000062143365,"about_ca_system_score_gemma":0.00042989777,"threshold_uncertainty_score":0.3647554},"labels":[],"label_agreement":null},{"id":"W2139446098","doi":"10.1038/cddis.2015.278","title":"NBR1 is dispensable for PARK2-mediated mitophagy regardless of the presence or absence of SQSTM1","year":2015,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research","keywords":"Mitophagy; Cell biology; Biology; Autophagy; Chemistry; Genetics; Apoptosis","score_opus":0.03642741280251954,"score_gpt":0.28925913473399323,"score_spread":0.2528317219314737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139446098","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99166906,0.00568441,0.00014040602,0.00027513024,0.0001379285,0.00070454605,0.00023802764,0.000016008655,0.0011344602],"genre_scores_gemma":[0.9942136,0.00023230376,0.00014890575,0.00061039475,0.00006696258,0.00004178535,0.000022344071,0.000014723611,0.004649025],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990983,0.000029463174,0.000222639,0.00021462089,0.00024252727,0.00019247801],"domain_scores_gemma":[0.9984819,0.00014430031,0.00012254289,0.00044366528,0.00016698721,0.00064058084],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009528406,0.00012676982,0.0002534642,0.00002894709,0.00004395569,0.000006279636,0.00013108218,0.000047957157,0.00009056215],"category_scores_gemma":[0.00041200637,0.00007455551,0.0001179197,0.00012070899,0.00016422289,0.00005687194,0.000045751218,0.000049383096,0.0000045603697],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.051400293,0.0059094126,0.74824977,0.008630141,0.00054752233,0.00037732976,0.0044653867,0.00007435513,0.026713915,0.0042999093,0.14478572,0.0045462623],"study_design_scores_gemma":[0.0381024,0.0022189103,0.5101307,0.0015667661,0.0017906673,0.000024273886,0.0016765742,0.012663495,0.37440944,0.016082093,0.040208045,0.0011266337],"about_ca_topic_score_codex":0.000029715284,"about_ca_topic_score_gemma":0.0000015093408,"teacher_disagreement_score":0.34769553,"about_ca_system_score_codex":0.000010735075,"about_ca_system_score_gemma":0.00047902408,"threshold_uncertainty_score":0.30402854},"labels":[],"label_agreement":null},{"id":"W2139830524","doi":"10.1158/1078-0432.ccr-10-2372","title":"Measurements of Tumor Cell Autophagy Predict Invasiveness, Resistance to Chemotherapy, and Survival in Melanoma","year":2011,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":233,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"National Center for Research Resources; National Cancer Institute; Abramson Cancer Center","keywords":"Autophagy; ATG5; Melanoma; Cancer research; Programmed cell death; Temozolomide; Small hairpin RNA; Medicine; Dacarbazine; Cell culture; Biology; Apoptosis; Pathology; Glioma; Gene knockdown","score_opus":0.2931685604140283,"score_gpt":0.46976088378464576,"score_spread":0.17659232337061748,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139830524","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883628,0.0028146564,0.0000072862113,0.00036930066,0.00014829347,0.0007230575,0.00001537937,0.000017824239,0.0075413845],"genre_scores_gemma":[0.99710673,0.0008256451,0.00030488765,0.00046081477,0.00015376991,0.00012692672,0.0000024197502,0.000030375386,0.0009884079],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99736714,0.00041008394,0.00059374253,0.00045800678,0.0007604462,0.00041057],"domain_scores_gemma":[0.9984772,0.0002885089,0.00007065075,0.00045243735,0.0003373575,0.00037380974],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0028877624,0.0001301533,0.00050221436,0.00017174531,0.000045577137,0.000007812342,0.00024669996,0.00010655328,0.00066913915],"category_scores_gemma":[0.00040565024,0.000111539244,0.00008629935,0.00044518587,0.000349102,0.000052813437,0.000099800614,0.00042646585,0.00001958009],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008248749,0.0011023359,0.9775059,0.00038853908,0.00010076466,0.00014139478,0.00061052246,6.7714825e-7,0.00631993,0.000064404,0.0010894111,0.00442737],"study_design_scores_gemma":[0.0042661405,0.0008210388,0.8775702,0.0003328817,0.000017836026,8.801477e-7,0.000078178666,0.0000069475122,0.11539517,0.00040238854,0.0010036681,0.00010463051],"about_ca_topic_score_codex":0.00055238436,"about_ca_topic_score_gemma":0.00053737557,"teacher_disagreement_score":0.10907525,"about_ca_system_score_codex":0.000095485935,"about_ca_system_score_gemma":0.0006630673,"threshold_uncertainty_score":0.7326605},"labels":[],"label_agreement":null},{"id":"W2139941678","doi":"10.2337/db06-1160","title":"Ubiquitinated-Protein Aggregates Form in Pancreatic β-Cells During Diabetes-Induced Oxidative Stress and Are Regulated by Autophagy","year":2007,"lang":"en","type":"article","venue":"Diabetes","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":220,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto; Hospital for Sick Children","funders":"","keywords":"Autophagy; Oxidative stress; Ubiquitin; Diabetes mellitus; Protein aggregation; Cell biology; Internal medicine; Endocrinology; Chemistry; Medicine; Biology; Biochemistry; Apoptosis","score_opus":0.006790827629662358,"score_gpt":0.2355528023129869,"score_spread":0.22876197468332454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139941678","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937848,0.0048215045,0.0000013785337,0.00010998781,0.000055558736,0.00077624316,0.000059893122,0.00016850847,0.00022216521],"genre_scores_gemma":[0.9989029,0.00007717328,0.000062983694,0.00024330139,0.00007741417,0.000068452624,0.00009195769,0.000059528204,0.00041624435],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979776,0.000060541697,0.00044104797,0.00046561685,0.00026588904,0.000789292],"domain_scores_gemma":[0.99892867,0.00015831868,0.00021794424,0.00033497508,0.00008333792,0.00027673852],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002866265,0.00034430504,0.00060017814,0.0002479958,0.000109632965,0.00003949778,0.00012069402,0.0002065117,0.0000947007],"category_scores_gemma":[0.000102443824,0.00031052402,0.00008438794,0.00037791673,0.00011932761,0.00019440832,0.000059956055,0.00027957343,0.000016465974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009117585,0.00027095128,0.13003106,0.0003945097,0.00016641025,0.000102873644,0.0003267694,6.703151e-7,0.86569357,0.000025636515,0.000023393317,0.0028729555],"study_design_scores_gemma":[0.002150693,0.0001906699,0.24730317,0.0010714628,0.00005694824,7.884552e-7,0.00024279578,0.00015703082,0.74826646,0.0002985445,0.000018925264,0.00024252213],"about_ca_topic_score_codex":0.00003402615,"about_ca_topic_score_gemma":0.00001011936,"teacher_disagreement_score":0.11742714,"about_ca_system_score_codex":0.0001147093,"about_ca_system_score_gemma":0.000034355508,"threshold_uncertainty_score":0.9999347},"labels":[],"label_agreement":null},{"id":"W2141533959","doi":"10.1038/emboj.2009.369","title":"Antagonism of Beclin 1‐dependent autophagy by BCL‐2 at the endoplasmic reticulum requires NAF‐1","year":2009,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":278,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Endoplasmic reticulum; Biology; Cell biology; Effector; Cytosol; Inositol; Receptor; Apoptosis; Biochemistry","score_opus":0.009856546554882509,"score_gpt":0.27849378780020784,"score_spread":0.26863724124532534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141533959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9734762,0.007618672,0.000058536036,0.01224837,0.00043550125,0.00024468455,0.000020822232,0.000030424193,0.0058668368],"genre_scores_gemma":[0.9877577,0.002060898,0.00003060046,0.003177365,0.0005635153,0.000003560428,0.000008674779,0.000020053198,0.0063776476],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982167,0.00018643851,0.0005017521,0.0001634148,0.0005798875,0.00035182454],"domain_scores_gemma":[0.9987722,0.0001331971,0.0003275687,0.00050329877,0.000088935434,0.00017480995],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007563613,0.00018901755,0.00032466897,0.00005024314,0.000398908,0.000036934107,0.00037234134,0.00007282142,0.0011413498],"category_scores_gemma":[0.00006456579,0.000093688956,0.0002530166,0.000111123205,0.000215393,0.00008042425,0.000049004677,0.0005230095,0.00007848039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002556518,0.0010709707,0.00082285964,0.000043027765,0.0009540231,0.0010007446,0.003727165,0.0000924185,0.83412206,0.0042756596,0.112858504,0.03847605],"study_design_scores_gemma":[0.0040086415,0.0011214685,0.00999387,0.00014636735,0.000430028,0.0055667046,0.00048526432,0.000272329,0.94475305,0.010772358,0.022223864,0.00022604284],"about_ca_topic_score_codex":0.000013723941,"about_ca_topic_score_gemma":0.0000023797238,"teacher_disagreement_score":0.110631004,"about_ca_system_score_codex":0.0000867475,"about_ca_system_score_gemma":0.00014555169,"threshold_uncertainty_score":0.9997717},"labels":[],"label_agreement":null},{"id":"W2141761940","doi":"10.1091/mbc.e08-08-0829","title":"Autophagy Provides Nutrients but Can Lead to Chop-dependent Induction of Bim to Sensitize Growth Factor–deprived Cells to Apoptosis","year":2008,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Cancer Institute; Tokyo Medical and Dental University; University of Pennsylvania","keywords":"Autophagy; Cell biology; Biology; Programmed cell death; Apoptosis; Growth factor; Intracellular; Biochemistry; Receptor","score_opus":0.013730276608500075,"score_gpt":0.251488469323289,"score_spread":0.23775819271478893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141761940","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955554,0.00014973542,0.001268717,0.0013207378,0.00036823048,0.0010725441,0.00007285423,0.000032036583,0.00015973789],"genre_scores_gemma":[0.995852,0.00004126132,0.0012334371,0.002236116,0.00005413597,0.000031189218,0.000011132162,0.000028610899,0.0005121331],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985923,0.00014651027,0.00033661825,0.000391011,0.00022838627,0.00030516819],"domain_scores_gemma":[0.99884135,0.000027334305,0.00013838669,0.00056929735,0.00019133075,0.0002322981],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009072935,0.00021367517,0.00042985918,0.00019690944,0.00007082184,0.000002765461,0.00026470993,0.00016913038,0.000033531185],"category_scores_gemma":[0.0000829656,0.0001615705,0.00023163499,0.00030659634,0.0001210433,0.000014434079,0.00016138502,0.00013894499,0.000042998625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028842018,0.00030835136,0.0016241473,0.000043540495,0.00011978577,0.000018338562,0.00068566116,0.000034733403,0.9962805,0.000034588786,0.00019393602,0.0003680095],"study_design_scores_gemma":[0.0009403813,0.00063865,0.013098293,0.00004330198,0.00007135198,0.000012640892,0.00008271198,0.0000032332446,0.9845869,0.00016137805,0.00021435859,0.00014677476],"about_ca_topic_score_codex":0.00043201432,"about_ca_topic_score_gemma":0.000006053316,"teacher_disagreement_score":0.011693563,"about_ca_system_score_codex":0.000078866666,"about_ca_system_score_gemma":0.00011855512,"threshold_uncertainty_score":0.65886533},"labels":[],"label_agreement":null},{"id":"W2141976152","doi":"10.1091/mbc.11.1.255","title":"Biogenesis of Multilamellar Bodies via Autophagy","year":2000,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":191,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; Université de Montréal","funders":"Medical Research Council; Medical Research Council Canada","keywords":"Vacuole; Biology; Autophagy; Leupeptin; Cell biology; Lysosome; Bafilomycin; Cytoplasm; Biochemistry; Protease; Apoptosis; Enzyme","score_opus":0.005517772855807227,"score_gpt":0.2505525536946293,"score_spread":0.24503478083882207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141976152","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99077934,0.0058035683,0.00021152274,0.00020595851,0.000070496,0.00018241488,0.00001826629,0.0000164227,0.0027120064],"genre_scores_gemma":[0.9974471,0.00023665227,0.0005558939,0.0004869261,0.00001856713,0.0000044632216,0.000010672183,0.000013741784,0.001226008],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932057,0.000082986575,0.00021474683,0.00015360065,0.000079825804,0.00014828386],"domain_scores_gemma":[0.9993569,0.000021019827,0.00008967549,0.00044853598,0.000041037223,0.000042802283],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007250171,0.00011193849,0.0002725948,0.000041798532,0.000028945682,7.584008e-7,0.00017921458,0.000121835736,0.0006170183],"category_scores_gemma":[0.000010452054,0.000073572875,0.00024380547,0.00008126798,0.0003001452,0.0000063083917,0.000032952037,0.000059809445,0.000028773644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011999423,0.00018126795,0.0021356444,0.00004721398,0.000113859096,0.000010608788,0.00007967889,0.000016653037,0.9918602,0.000054769178,0.00007383594,0.0053062695],"study_design_scores_gemma":[0.00071657967,0.00017514083,0.005654626,0.000018177969,0.00011791922,0.000007901761,0.000007843203,0.000076069155,0.9901763,0.0007624546,0.0022230586,0.00006391735],"about_ca_topic_score_codex":0.000046526962,"about_ca_topic_score_gemma":6.953922e-7,"teacher_disagreement_score":0.0066677313,"about_ca_system_score_codex":0.0000079594,"about_ca_system_score_gemma":0.00003544732,"threshold_uncertainty_score":0.6755918},"labels":[],"label_agreement":null},{"id":"W2143404258","doi":"10.1083/jcb.201005067","title":"Rescue of myogenic defects in Rb-deficient cells by inhibition of autophagy or by hypoxia-induced glycolytic shift","year":2010,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Myogenesis; Biology; Autophagy; Cell biology; Retinoblastoma protein; Myocyte; Programmed cell death; Mitochondrion; E2F; Glycolysis; Apoptosis; Cell cycle; Biochemistry; Metabolism","score_opus":0.010433425685787007,"score_gpt":0.2637382426736836,"score_spread":0.25330481698789664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2143404258","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976344,0.0013566788,0.00003457011,0.00014560195,0.00029947847,0.00023101308,0.000021527265,0.0000052434366,0.00027150026],"genre_scores_gemma":[0.99912345,0.0003657867,0.00004876554,0.0002523017,0.000071906565,0.0000020032417,0.0000068624245,0.000015461013,0.00011347094],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99857277,0.00021890446,0.0006911849,0.00011056283,0.00017532513,0.00023124198],"domain_scores_gemma":[0.99870366,0.00028064224,0.0005385195,0.00026272956,0.00011143513,0.00010303997],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007417427,0.00014238308,0.0004923486,0.00015735278,0.00002679335,0.0000022993136,0.00018629787,0.00020475838,0.00026960968],"category_scores_gemma":[0.00008039589,0.000082224054,0.00015363668,0.0002027061,0.00017803085,0.00003557685,0.000031978536,0.00047293786,0.0000091143875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017786213,0.000538299,0.00018720851,0.000044267334,0.000048034995,0.000020521811,0.0003315629,0.0000075669022,0.99616265,0.000041246614,0.00037206602,0.00046796413],"study_design_scores_gemma":[0.002994604,0.0022928116,0.0030386155,0.000059992188,0.00012697959,0.000050857656,0.00008181885,0.000026830221,0.9905412,0.00039280741,0.00031879818,0.000074665295],"about_ca_topic_score_codex":0.00005880872,"about_ca_topic_score_gemma":0.000024760579,"teacher_disagreement_score":0.0056214207,"about_ca_system_score_codex":0.00003472179,"about_ca_system_score_gemma":0.00023460227,"threshold_uncertainty_score":0.33529997},"labels":[],"label_agreement":null},{"id":"W2144103034","doi":"10.4161/auto.5901","title":"Molecular regulation of autophagy and apoptosis during ischemic and non-ischemic cardiomyopathy","year":2008,"lang":"en","type":"review","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Manitoba Health Research Council","keywords":"Autophagy; Biology; Apoptosis; Cell biology; Heart failure; Programmed cell death; Mitochondrion; Cardiomyopathy; Disease; Signal transduction; Internal medicine; Genetics; Medicine","score_opus":0.01238850677831775,"score_gpt":0.2780481185915756,"score_spread":0.2656596118132578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144103034","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23544744,0.76244986,0.00002148518,0.000008368939,0.00009869205,0.00077178417,0.000029406398,0.00007752733,0.0010954125],"genre_scores_gemma":[0.082640335,0.9160682,0.00026679668,0.000044468637,0.00018365454,0.000111140675,0.00013731785,0.0001248709,0.00042319426],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975075,0.00008224376,0.00084856414,0.00076569023,0.00039144457,0.0004045496],"domain_scores_gemma":[0.9982779,0.00008069344,0.00049726653,0.00076951704,0.00009404577,0.00028059437],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011425592,0.00065952,0.0024748368,0.0003712817,0.00010500174,0.000018558647,0.00015753307,0.000570743,0.00005567861],"category_scores_gemma":[0.000050069513,0.0005939476,0.00059247814,0.0003734221,0.00026062044,0.00011391454,0.00015543298,0.00041337922,0.000015877295],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017286208,0.0002943497,0.00010895283,0.060026355,0.0028695134,0.0005721329,0.0005268244,0.0000031284478,0.070570454,0.00012721444,0.0010997164,0.8636285],"study_design_scores_gemma":[0.0069832155,0.00053881074,0.005589188,0.02911951,0.008026964,0.0053279274,0.00004786041,0.00015131582,0.3412533,0.000096328185,0.60055995,0.0023056034],"about_ca_topic_score_codex":0.000020619003,"about_ca_topic_score_gemma":9.833618e-8,"teacher_disagreement_score":0.8613229,"about_ca_system_score_codex":0.000097482516,"about_ca_system_score_gemma":0.00030216275,"threshold_uncertainty_score":0.9996512},"labels":[],"label_agreement":null},{"id":"W2144149966","doi":"10.1016/j.bbamcr.2013.04.011","title":"Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity: Differences between primary and cancer cells","year":2013,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":145,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Linköpings Universitet; Cancerfonden","keywords":"Salinomycin; Autophagy; Mitophagy; Cell biology; Mitochondrion; Cancer cell; Wnt signaling pathway; Biology; Cancer stem cell; Apoptosis; Context (archaeology); Cancer research; Chemistry; Stem cell; Cancer; Biochemistry; Signal transduction; Genetics","score_opus":0.03283342492425775,"score_gpt":0.3236690386424312,"score_spread":0.29083561371817346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144149966","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952692,0.0013116596,0.000027738532,0.001272134,0.000084387415,0.0013939821,0.00005133075,0.000043729287,0.0005458772],"genre_scores_gemma":[0.9974839,0.0010427554,0.00044863077,0.00025523966,0.0003036816,0.00012614609,0.00007456852,0.00005689285,0.00020817657],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970152,0.00046984712,0.00034190097,0.0007016428,0.00089854666,0.00057288515],"domain_scores_gemma":[0.99825186,0.0004139723,0.00017940649,0.0005018428,0.00024994966,0.00040297862],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025669488,0.00034376272,0.0006345168,0.00036896416,0.00016417415,0.00012992723,0.00026614347,0.00030079504,0.00006790535],"category_scores_gemma":[0.000049502883,0.00029141485,0.00013567897,0.0004739914,0.00057614094,0.0002327663,0.00027652478,0.00064948323,0.0000118025855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020560485,0.0003313297,0.00022891213,0.00044286103,0.00021190912,0.000012656923,0.00036126675,9.9844506e-8,0.9938395,0.00005253607,0.0002826329,0.004030714],"study_design_scores_gemma":[0.0014524464,0.0005762061,0.11533375,0.00017314243,0.0000911166,0.0000013084031,0.00007220859,0.000033596443,0.88160044,0.00039233253,0.000044151504,0.00022927443],"about_ca_topic_score_codex":0.000787249,"about_ca_topic_score_gemma":0.0000013227072,"teacher_disagreement_score":0.11510484,"about_ca_system_score_codex":0.00007291131,"about_ca_system_score_gemma":0.00040490652,"threshold_uncertainty_score":0.9999538},"labels":[],"label_agreement":null},{"id":"W2144409921","doi":"10.1083/jcb.200904075","title":"The conserved oligomeric Golgi complex is involved in double-membrane vesicle formation during autophagy","year":2010,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":198,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences","keywords":"Cell biology; Biology; Autophagosome; Autophagy; Cytoplasm; Lipid bilayer fusion; Golgi apparatus; Vesicle; ATG8; Vesicular transport protein; Vacuole; Vesicle fusion; Biochemistry; Membrane; Synaptic vesicle; Endoplasmic reticulum","score_opus":0.022682317263605218,"score_gpt":0.28349364296251894,"score_spread":0.26081132569891374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144409921","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959245,0.0008395473,0.00001698721,0.0019383462,0.00029366984,0.00018003727,0.000001892627,0.000010508542,0.00079454854],"genre_scores_gemma":[0.9976484,0.00091678783,0.000059376096,0.0009925158,0.0001917692,0.0000027390452,0.0000033831793,0.000010002021,0.00017498092],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900645,0.00013264037,0.00046353892,0.00006320652,0.00010699362,0.00022716659],"domain_scores_gemma":[0.9990118,0.00020757555,0.00035248284,0.00024381942,0.000103574406,0.00008074388],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061387377,0.00010686263,0.00025559,0.00008158528,0.00014146316,0.000011598496,0.0002500012,0.00008794368,0.00019619234],"category_scores_gemma":[0.000023923194,0.000054251028,0.00009723133,0.00014631558,0.00020278622,0.000078551995,0.000031712458,0.00044300308,0.000027091732],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00167819,0.00007603065,0.00066789414,0.000023557715,0.000042882562,0.000015716794,0.000626459,0.0000054915026,0.9960351,0.00019029315,0.000094431154,0.00054397836],"study_design_scores_gemma":[0.0054605138,0.0002669519,0.046216648,0.000019214081,0.000057346613,0.00019295377,0.00027570713,0.00037956313,0.9425326,0.00080734334,0.0037209974,0.000070174196],"about_ca_topic_score_codex":0.00003424081,"about_ca_topic_score_gemma":0.000039317594,"teacher_disagreement_score":0.05350249,"about_ca_system_score_codex":0.000031112482,"about_ca_system_score_gemma":0.00009236905,"threshold_uncertainty_score":0.22122927},"labels":[],"label_agreement":null},{"id":"W2144451481","doi":"10.25011/cim.v36i2.19569","title":"Pancreatic islet cell autophagy during aging in rats","year":2013,"lang":"en","type":"article","venue":"Clinical and investigative medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autophagy; Islet; Internal medicine; Endocrinology; Medicine; Cell biology; Diabetes mellitus; Chemistry; Biology; Apoptosis; Biochemistry","score_opus":0.08763890334362907,"score_gpt":0.3393232397584946,"score_spread":0.25168433641486554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144451481","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9803768,0.0023613884,0.000009883754,0.013513594,0.00018746784,0.00047826028,0.0000011611177,0.00005690776,0.0030145757],"genre_scores_gemma":[0.9895636,0.00069981825,0.00028333042,0.0063961693,0.0006415344,0.000049831917,0.000014075189,0.000021184445,0.0023304818],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99823534,0.0001569336,0.00071308215,0.00039765693,0.00020128685,0.00029571028],"domain_scores_gemma":[0.9987834,0.00021927664,0.00012462046,0.0002529501,0.00007526223,0.0005444987],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.00037430885,0.00021093954,0.00068733015,0.00011427019,0.000065809196,0.000009166864,0.00007921292,0.00011467759,0.000873224],"category_scores_gemma":[0.0006150628,0.0001419046,0.00006850163,0.00023905955,0.0035215293,0.00015572578,0.000050827333,0.00044879603,0.00011027114],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015039992,0.0006049678,0.8579546,0.0006950972,0.0001763533,0.0004800458,0.0026526237,0.0000018967352,0.1221054,0.0020093916,0.005453743,0.007715437],"study_design_scores_gemma":[0.0052761612,0.0006271971,0.9496974,0.0007915384,0.00009128414,0.000017921546,0.0004176239,0.00035660923,0.020764166,0.021259552,0.0005308754,0.00016971095],"about_ca_topic_score_codex":0.00016139924,"about_ca_topic_score_gemma":0.0000029203097,"teacher_disagreement_score":0.10134123,"about_ca_system_score_codex":0.000021005935,"about_ca_system_score_gemma":0.00007132695,"threshold_uncertainty_score":0.99919033},"labels":[],"label_agreement":null},{"id":"W2144577174","doi":"10.1152/ajpcell.00270.2013","title":"p53 is necessary for the adaptive changes in cellular milieu subsequent to an acute bout of endurance exercise","year":2013,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Mitophagy; Mitochondrial biogenesis; Autophagy; Endurance training; Endocrinology; Mitochondrion; Internal medicine; Coactivator; Biology; Cell biology; Chemistry; Medicine; Apoptosis; Biochemistry; Gene; Transcription factor","score_opus":0.0131784162495147,"score_gpt":0.27302532748876945,"score_spread":0.25984691123925474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144577174","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952839,0.0016188897,0.00011883065,0.0018965878,0.00020789595,0.0008057005,0.000036204976,0.000009761411,0.000022234128],"genre_scores_gemma":[0.9932022,0.0014284565,0.0009792566,0.0037835087,0.00034161427,0.00013212881,0.000013964065,0.000036384947,0.000082462226],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982495,0.00017855695,0.0005528743,0.00034422538,0.00016333193,0.0005115144],"domain_scores_gemma":[0.9979618,0.00026193445,0.0007172197,0.00050264515,0.0003325915,0.00022379123],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001902082,0.0002789616,0.0011299556,0.00018944565,0.00006414101,0.000004184184,0.00047311612,0.0000909862,0.00020282302],"category_scores_gemma":[0.000018421308,0.00018149812,0.00028586137,0.00031325154,0.00064775586,0.00011614881,0.000060329807,0.00033959595,0.00001968734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032077825,0.00050464575,0.00009026981,0.000040165203,0.00027932617,0.0000075181774,0.0013559355,0.00018806386,0.98657894,0.000027491902,0.0011164236,0.0066034542],"study_design_scores_gemma":[0.0038713436,0.01469204,0.14250445,0.00020152326,0.0004664283,0.000026710954,0.0059303404,0.0007573193,0.8265251,0.0040543554,0.0005844253,0.0003859388],"about_ca_topic_score_codex":0.00026838089,"about_ca_topic_score_gemma":0.000008132902,"teacher_disagreement_score":0.1600538,"about_ca_system_score_codex":0.00005015792,"about_ca_system_score_gemma":0.00016353789,"threshold_uncertainty_score":0.74012786},"labels":[],"label_agreement":null},{"id":"W2147995582","doi":"10.1371/journal.pone.0121059","title":"Calnexin Is Essential for Survival under Nitrogen Starvation and Stationary Phase in Schizosaccharomyces pombe","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; Schizosaccharomyces pombe; Vacuole; Programmed cell death; Endoplasmic reticulum; Biology; Calnexin; Lysosome; Saccharomyces cerevisiae; Calreticulin; Apoptosis; Biochemistry; Yeast; Cytoplasm","score_opus":0.11507154245778055,"score_gpt":0.3379563110813334,"score_spread":0.22288476862355283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147995582","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99631214,0.00058483984,0.00046996734,0.0018336853,0.000029723577,0.00050950056,0.00012495776,0.000030565425,0.000104645835],"genre_scores_gemma":[0.9968844,0.000062719744,0.0016016412,0.0007276278,0.00015870847,0.000059541693,0.00030575928,0.000017622113,0.00018199188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99927944,0.000027189064,0.00015701477,0.00015889076,0.00024717022,0.00013027457],"domain_scores_gemma":[0.999564,0.000054026976,0.000043246826,0.000102421945,0.00011247832,0.00012381839],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013371234,0.00008333889,0.00018131163,0.00008013797,0.000028954226,0.000011878165,0.0000296916,0.00004800024,0.000104074745],"category_scores_gemma":[0.00004786521,0.00007961209,0.00002337144,0.000085091975,0.000032416607,0.0001254344,0.000011609641,0.00005930859,0.000010905644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.04336569,0.061342496,0.32237056,0.0022577785,0.0064002518,0.00027058373,0.013955275,0.00003326646,0.5002289,0.024172843,0.0119332075,0.013669182],"study_design_scores_gemma":[0.10265981,0.0047939257,0.06430277,0.0007367087,0.0016966478,0.000013427531,0.0039537963,0.017188827,0.58859116,0.2137714,0.0011946509,0.0010968802],"about_ca_topic_score_codex":0.000041907762,"about_ca_topic_score_gemma":0.000011546544,"teacher_disagreement_score":0.2580678,"about_ca_system_score_codex":0.000037152946,"about_ca_system_score_gemma":0.00013860471,"threshold_uncertainty_score":0.32464868},"labels":[],"label_agreement":null},{"id":"W2148229868","doi":"10.1139/bcb-2014-0123","title":"γ-Tocotrienol-induced endoplasmic reticulum stress and autophagy act concurrently to promote breast cancer cell death","year":2015,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Tulane University","keywords":"Autophagy; Endoplasmic reticulum; Unfolded protein response; Programmed cell death; Apoptosis; Cell biology; Viability assay; CHOP; Biology; Cancer research; Chemistry; Biochemistry","score_opus":0.016560432818769986,"score_gpt":0.28246310613102604,"score_spread":0.26590267331225603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2148229868","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911372,0.0047943895,0.0000052513456,0.00023285861,0.00016024627,0.00036141716,0.0002138319,0.000049000006,0.0030458255],"genre_scores_gemma":[0.99781346,0.0004857711,0.00006762103,0.0003309944,0.00025044524,0.00006300647,0.00008372546,0.000017164853,0.0008878009],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891114,0.000029230616,0.00018863416,0.00046152822,0.000083338935,0.00032612472],"domain_scores_gemma":[0.9990262,0.000019103438,0.00007557035,0.0002409051,0.000083785286,0.00055443915],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007319915,0.00023098604,0.00030134764,0.00002252513,0.00005694468,0.000015789634,0.00008913161,0.00024172968,0.0001445574],"category_scores_gemma":[0.000013635158,0.00018936023,0.00004374238,0.000065489185,0.00009471025,0.000028760787,0.000077573575,0.00014718181,0.000010961612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003914489,0.00022396733,0.008981717,0.00021627473,0.000050260787,0.00004416597,0.00023290915,2.9568008e-7,0.9837497,0.000022345283,0.00027357193,0.0058133504],"study_design_scores_gemma":[0.0023491275,0.0003666399,0.0029009145,0.00006817351,0.000083772764,0.00008726925,0.00016617999,0.00004430501,0.9904189,0.000036209858,0.0032624,0.0002160928],"about_ca_topic_score_codex":0.000099469275,"about_ca_topic_score_gemma":0.0000026206565,"teacher_disagreement_score":0.006676291,"about_ca_system_score_codex":0.000048475664,"about_ca_system_score_gemma":0.00023409736,"threshold_uncertainty_score":0.7721886},"labels":[],"label_agreement":null},{"id":"W2148894885","doi":"10.1038/cr.2009.129","title":"S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3","year":2009,"lang":"en","type":"article","venue":"Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":280,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba; CancerCare Manitoba","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; CancerCare Manitoba Foundation; National Institutes of Health; Deutsche Forschungsgemeinschaft; Deutsche Krebshilfe; Manitoba Health Research Council","keywords":"Programmed cell death; Autophagy; Cell biology; Biology; ATG5; Mitochondrion; Apoptosis; Reactive oxygen species; Bafilomycin; Vacuole; Cytoplasm; Biochemistry","score_opus":0.07420105121293813,"score_gpt":0.38634062116393997,"score_spread":0.31213956995100184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2148894885","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9848249,0.010273147,0.000013217419,0.0008667447,0.0000825452,0.00063240796,0.000023470506,0.00010597583,0.0031775709],"genre_scores_gemma":[0.9935417,0.0024658302,0.00015760506,0.00032641474,0.00038620998,0.000032937613,0.0000906848,0.0000392447,0.0029593713],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99725574,0.00018719933,0.00029915842,0.0006221067,0.0008691594,0.0007666571],"domain_scores_gemma":[0.99801993,0.0005394059,0.00006869975,0.00048640568,0.00020782756,0.0006777537],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006194033,0.00027222486,0.00048096117,0.00041306322,0.00036957586,0.00021136145,0.00023124438,0.00030843954,0.0003220368],"category_scores_gemma":[0.00015212633,0.00022562669,0.00008623056,0.00049834355,0.00060767296,0.00026292983,0.00013296564,0.00067832804,0.00007616017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007251919,0.0006709225,0.13552892,0.00046007815,0.0002808822,0.00023562822,0.002215194,6.702814e-7,0.78145576,0.0001156374,0.0038016152,0.0745095],"study_design_scores_gemma":[0.0024646942,0.0007221551,0.47451583,0.00009004041,0.000048849273,0.000009982897,0.0002523592,0.000056840632,0.5172311,0.0017586406,0.0026198763,0.00022960996],"about_ca_topic_score_codex":0.00008383581,"about_ca_topic_score_gemma":0.000002249476,"teacher_disagreement_score":0.3389869,"about_ca_system_score_codex":0.00006526881,"about_ca_system_score_gemma":0.00017509625,"threshold_uncertainty_score":0.920079},"labels":[],"label_agreement":null},{"id":"W2149390768","doi":"10.1128/jvi.02974-12","title":"Inhibition of the Host Translation Shutoff Response by Herpes Simplex Virus 1 Triggers Nuclear Envelope-Derived Autophagy","year":2013,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; National Eye Institute; Deutsche Forschungsgemeinschaft","keywords":"Biology; Herpes simplex virus; Autophagy; Cell biology; Viral protein; Viral envelope; Virus; Virology; Stress granule; Translation (biology); Apoptosis; Messenger RNA; Biochemistry; Gene","score_opus":0.012647285602516782,"score_gpt":0.25711360564664515,"score_spread":0.24446632004412835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149390768","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99056774,0.0009422822,0.00013904215,0.0078034713,0.00019695032,0.00022403004,0.00000901532,0.000010938324,0.00010654905],"genre_scores_gemma":[0.9957143,0.00021946106,0.00020704627,0.0036330987,0.00012443347,0.000002594468,0.0000020966852,0.000022705948,0.00007425344],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985284,0.00035862724,0.00059595634,0.00009696039,0.00025455738,0.00016549221],"domain_scores_gemma":[0.99879336,0.0002015007,0.00055884145,0.00016992012,0.00016601346,0.000110378656],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00041100523,0.00012494222,0.0003799204,0.00013092131,0.000053199932,0.000009866175,0.00012226075,0.00016833942,0.0010532883],"category_scores_gemma":[0.00012444216,0.00008079981,0.00024103063,0.00013554563,0.00016445415,0.00018505423,0.0000128845895,0.00022535253,0.000032997348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005244919,0.00025585922,0.00006819945,0.000010811044,0.00015437527,0.000042040836,0.0008216479,0.000009621063,0.976145,0.000019428384,0.0036494546,0.013578639],"study_design_scores_gemma":[0.010628291,0.0033656636,0.2911099,0.000107735155,0.00036758292,0.0003802983,0.0003654382,0.00030392097,0.5873459,0.00087505725,0.10495164,0.00019855188],"about_ca_topic_score_codex":0.000020302632,"about_ca_topic_score_gemma":0.0000016029953,"teacher_disagreement_score":0.38879907,"about_ca_system_score_codex":0.000045364683,"about_ca_system_score_gemma":0.00015255879,"threshold_uncertainty_score":0.99985987},"labels":[],"label_agreement":null},{"id":"W2149857058","doi":"10.4049/jimmunol.1201404","title":"Rescue of Dysfunctional Autophagy Attenuates Hyperinflammatory Responses from Cystic Fibrosis Cells","year":2012,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Child and Family Research Institute; BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Dysfunctional family; Cystic fibrosis; Fibrosis; Medicine; Cancer research; Cell biology; Immunology; Neuroscience; Biology; Pathology; Internal medicine; Apoptosis; Genetics","score_opus":0.013304816474719327,"score_gpt":0.2539801496783146,"score_spread":0.2406753332035953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149857058","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9766818,0.021870485,0.00008404834,0.0003799332,0.00076315086,0.00007419001,0.000017128013,0.000010867507,0.00011836939],"genre_scores_gemma":[0.99772066,0.00076570327,0.00035491388,0.00019978636,0.00045103478,0.0000016669183,0.0000032068504,0.000016758064,0.00048627],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99872917,0.0003163246,0.00047860754,0.000055628792,0.00020788448,0.00021241378],"domain_scores_gemma":[0.99843854,0.00070840225,0.00033330827,0.00028237957,0.00016206225,0.000075292905],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00057095283,0.00011722941,0.00036333266,0.00012095579,0.000063596686,0.0000029940952,0.00018434419,0.00010109496,0.0009476521],"category_scores_gemma":[0.00016031101,0.00007183057,0.00015809535,0.00008508835,0.00025604424,0.00010684956,0.000042483673,0.0002840076,0.00008281254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007530216,0.0001907806,0.0033274482,0.000012932262,0.00074480375,0.000024328958,0.0006647636,0.000012850634,0.9853353,0.0001237762,0.0006976398,0.0013351539],"study_design_scores_gemma":[0.001607744,0.0006605962,0.37258452,0.000090733876,0.00037713305,0.00046546358,0.00029339857,0.000010090548,0.61969113,0.00027219954,0.0038761678,0.0000707861],"about_ca_topic_score_codex":0.00003454461,"about_ca_topic_score_gemma":4.5967732e-7,"teacher_disagreement_score":0.3692571,"about_ca_system_score_codex":0.000046477617,"about_ca_system_score_gemma":0.00016403219,"threshold_uncertainty_score":0.9999656},"labels":[],"label_agreement":null},{"id":"W2150043714","doi":"10.1038/sj.cdd.4402039","title":"Autophagy delays apoptotic death in breast cancer cells following DNA damage","year":2006,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":519,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pediatric Oncology Group","funders":"","keywords":"Autophagy; Programmed cell death; Apoptosis; Cell biology; Vacuole; DNA damage; Biology; Mitochondrion; Cancer cell; Caspase; Cancer research; Cancer; Biochemistry; DNA","score_opus":0.008164367931392155,"score_gpt":0.24104044167526717,"score_spread":0.232876073743875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2150043714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99598724,0.0011415816,0.0004645877,0.000076790035,0.00021330973,0.00026358428,0.000020536108,0.000057075416,0.0017753042],"genre_scores_gemma":[0.9984212,0.00018649906,0.00008322791,0.00021200757,0.00016770957,0.000029187959,0.0001338129,0.000024070461,0.0007423202],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990132,0.000032549928,0.00023562358,0.00027280595,0.00017345943,0.0002723693],"domain_scores_gemma":[0.99959785,0.000025283756,0.000067840374,0.00016401357,0.000025358231,0.00011966916],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000056823214,0.00017882278,0.00024491944,0.000131669,0.00007814579,0.000036722686,0.000046646062,0.00010331588,0.00019430948],"category_scores_gemma":[0.0000020976508,0.00015741834,0.00009919172,0.00011332134,0.000012926017,0.00011285074,0.00001896866,0.00010909419,0.000015451107],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025702282,0.0008943486,0.6814537,0.00025345478,0.00007805955,0.00015571037,0.00026404302,0.00009550553,0.31319347,0.0009735542,0.00028881532,0.0020923153],"study_design_scores_gemma":[0.0024719364,0.000035897963,0.921395,0.0000731536,0.00015794027,0.0000046916693,0.000017426508,0.0037794134,0.07116363,0.0007114917,0.00003590452,0.00015354014],"about_ca_topic_score_codex":0.00038091678,"about_ca_topic_score_gemma":0.00002498998,"teacher_disagreement_score":0.24202985,"about_ca_system_score_codex":0.000077307035,"about_ca_system_score_gemma":0.00005172315,"threshold_uncertainty_score":0.6419334},"labels":[],"label_agreement":null},{"id":"W2151390901","doi":"10.1158/1078-0432.ccr-11-2465","title":"<i>Here, There Be Dragons</i> : Charting Autophagy-Related Alterations in Human Tumors","year":2012,"lang":"en","type":"review","venue":"Clinical Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Cancer; Carcinogenesis; Cell biology; Cancer research; Cancer cell; Function (biology); Lysosome; Genetics; Biochemistry; Apoptosis","score_opus":0.46429398715904197,"score_gpt":0.6077967453604527,"score_spread":0.14350275820141073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151390901","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007059036,0.9831409,8.4851507e-7,0.00046668845,0.00041500133,0.0022079581,0.000075390155,0.00010224238,0.0065319496],"genre_scores_gemma":[0.010007894,0.9792177,0.00001513305,0.00036166757,0.001721993,0.0011416636,0.00026703312,0.00015956887,0.0071073296],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99280345,0.0019087733,0.0022840735,0.00088576745,0.0009427353,0.0011752169],"domain_scores_gemma":[0.9960656,0.0014521657,0.0003961051,0.0010906316,0.00026942854,0.0007260445],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0050619952,0.0004639216,0.0024491218,0.00047219163,0.000338607,0.00007088103,0.00056132814,0.00085071137,0.003721567],"category_scores_gemma":[0.00054377306,0.00035724224,0.00094361743,0.0012678611,0.00059316115,0.0001277644,0.00025468206,0.0046094987,0.0004435738],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009283895,0.0012087512,0.0013423437,0.00754508,0.0005503363,0.00043807668,0.00018581262,5.5405104e-7,0.0000074596464,0.0011710236,0.002164545,0.98529315],"study_design_scores_gemma":[0.0015873334,0.00032051373,0.0010265147,0.01871766,0.0005358345,0.00002277241,0.00007219519,0.000011191901,0.000015508946,0.0003685314,0.9769252,0.0003967364],"about_ca_topic_score_codex":0.00026072274,"about_ca_topic_score_gemma":0.000099916004,"teacher_disagreement_score":0.9848964,"about_ca_system_score_codex":0.0004723583,"about_ca_system_score_gemma":0.0023559814,"threshold_uncertainty_score":0.99988794},"labels":[],"label_agreement":null},{"id":"W2151446023","doi":"10.1074/mcp.m112.025775","title":"Quantitative Proteomics Reveals the Induction of Mitophagy in Tumor Necrosis Factor-α-activated (TNFα) Macrophages","year":2013,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Mitophagy; Tumor necrosis factor alpha; Cell biology; Antigen presentation; Biology; Acquired immune system; Antigen processing; Immune system; Innate immune system; Antigen; Cytokine; Mitochondrion; MHC class I; Proteomics; Immunology; Major histocompatibility complex; T cell; Autophagy; Biochemistry; Apoptosis; Gene","score_opus":0.015606102405983972,"score_gpt":0.26160706042324616,"score_spread":0.24600095801726218,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151446023","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906513,0.0007600246,0.0032369513,0.00053888,0.000118910844,0.0045055384,0.000027272967,0.00005266172,0.000108440334],"genre_scores_gemma":[0.9914965,0.00005711343,0.0070679,0.0004125926,0.000050529514,0.000595683,0.000050816885,0.00008195249,0.00018688737],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99779135,0.00027617393,0.0006478809,0.00045201418,0.00039877964,0.00043379568],"domain_scores_gemma":[0.99847376,0.000052285057,0.00038302058,0.00069017167,0.0002563811,0.00014437706],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025726252,0.00034956558,0.0005634861,0.0002016129,0.00009479205,0.000049853767,0.00027583737,0.00019617344,0.00023540006],"category_scores_gemma":[0.00017371705,0.00026697712,0.00024212811,0.0005603536,0.0002399396,0.00018201422,0.00008197915,0.0005052688,0.00006217835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030574715,0.00030339498,0.0026093675,0.0001431467,0.00015739811,0.000105078165,0.00054891984,0.000038579128,0.9949365,0.0005254815,0.000038378686,0.00028795953],"study_design_scores_gemma":[0.0015595544,0.00042445175,0.014118401,0.00015342003,0.000053957265,0.000022061722,0.00029250147,0.0005578885,0.97945935,0.0030891455,0.00002272081,0.0002465589],"about_ca_topic_score_codex":0.00043288016,"about_ca_topic_score_gemma":0.000003818535,"teacher_disagreement_score":0.01547721,"about_ca_system_score_codex":0.00013568123,"about_ca_system_score_gemma":0.00016475923,"threshold_uncertainty_score":0.99997824},"labels":[],"label_agreement":null},{"id":"W2152604814","doi":"10.4161/auto.6486","title":"A dual role of p53 in the control of autophagy","year":2008,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":335,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer; Ministero della Salute; Fondation pour la Recherche Médicale; Fondazione Telethon; Ligue Contre le Cancer; Compagnia di San Paolo","keywords":"Autophagy; Biology; Cell biology; ATG5; BAG3; ATG12; Ubiquitin; Biochemistry; Apoptosis; Gene","score_opus":0.011252693797133957,"score_gpt":0.2549898457014758,"score_spread":0.24373715190434186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2152604814","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989646,0.004485621,0.00006148332,0.0002278528,0.00007090021,0.00041901245,0.000021140251,0.000032679825,0.0050353017],"genre_scores_gemma":[0.99841475,0.00014367301,0.00009597766,0.0008813089,0.00010447699,0.000034980323,0.000009219297,0.000018640265,0.0002969835],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985831,0.00010934111,0.00047053938,0.00019139524,0.00039214952,0.00025349687],"domain_scores_gemma":[0.9990247,0.00017902147,0.00016378013,0.00048187404,0.00008113059,0.000069532674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025339803,0.00015433473,0.00048755115,0.00013649123,0.00004176319,0.0000023850273,0.00018021757,0.00010380179,0.00034062366],"category_scores_gemma":[0.000074592004,0.000106899264,0.00019229644,0.0003114491,0.00023365766,0.000061494145,0.00001951816,0.00017572432,0.000026884423],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0050581507,0.009817971,0.10351993,0.00061663456,0.0015926469,0.004687738,0.03572762,0.00026848674,0.7183798,0.07065827,0.0035179842,0.046154775],"study_design_scores_gemma":[0.008027891,0.0008655889,0.75785923,0.000082947954,0.00014173973,0.00042127812,0.00053727557,0.0011607293,0.22483115,0.002340602,0.0035522904,0.00017929553],"about_ca_topic_score_codex":0.00013761575,"about_ca_topic_score_gemma":0.0000042484476,"teacher_disagreement_score":0.6543393,"about_ca_system_score_codex":0.00002140182,"about_ca_system_score_gemma":0.00020235054,"threshold_uncertainty_score":0.43592253},"labels":[],"label_agreement":null},{"id":"W2154887758","doi":"10.1074/jbc.m808515200","title":"Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":955,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Deafness and Other Communication Disorders; National Institute on Aging; National Institutes of Health; University of Pittsburgh; American Parkinson Disease Association; Pittsburgh Foundation","keywords":"PINK1; Mitophagy; Parkin; Mitochondrial fission; Autophagy; Cell biology; Mitochondrion; Biology; Gene knockdown; mitochondrial fusion; MFN1; Mitochondrial DNA; Apoptosis; Biochemistry; Parkinson's disease; Medicine","score_opus":0.015492390031753008,"score_gpt":0.2836188605905937,"score_spread":0.2681264705588407,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2154887758","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976931,0.0012226928,0.00010666128,0.00038008776,0.00010343191,0.000104469655,0.000005631889,0.00000946414,0.0003744348],"genre_scores_gemma":[0.9982961,0.0002857225,0.0003229775,0.0002678955,0.00076365157,0.0000010469201,0.0000091612055,0.0000037957436,0.000049672264],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925935,0.00003596899,0.00028289994,0.00013225694,0.00017640395,0.00011313808],"domain_scores_gemma":[0.9992867,0.0001300622,0.0002792908,0.000097636046,0.000095667005,0.0001106128],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000060290873,0.00012497358,0.000341067,0.000016017395,0.000029896337,0.000005733268,0.000061495084,0.00019051881,0.000088188266],"category_scores_gemma":[0.00021368041,0.0000720491,0.00012966056,0.000061230516,0.00008023434,0.00004693389,0.000011072987,0.0002488509,9.483932e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003291386,0.00053941447,0.002010173,0.00011768043,0.00008881404,0.00013149073,0.00005250207,8.74356e-7,0.9876178,0.000015142933,0.0001964417,0.005938299],"study_design_scores_gemma":[0.0020339475,0.0036737453,0.04084537,0.00046145805,0.000055741708,0.00008059298,0.000034551715,0.0000025175893,0.95057225,0.0020181262,0.00015383822,0.000067832814],"about_ca_topic_score_codex":3.726867e-7,"about_ca_topic_score_gemma":8.209832e-9,"teacher_disagreement_score":0.0388352,"about_ca_system_score_codex":0.00002211612,"about_ca_system_score_gemma":0.00003291099,"threshold_uncertainty_score":0.29380772},"labels":[],"label_agreement":null},{"id":"W2155658952","doi":"10.1016/j.ceb.2009.12.007","title":"Targeting cancer cells through autophagy for anticancer therapy","year":2010,"lang":"en","type":"review","venue":"Current Opinion in Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":114,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Hôpital Notre-Dame","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Cell biology; Autophagosome; Cancer cell; Organelle; Cytoplasm; Cancer; Apoptosis; Biochemistry; Genetics","score_opus":0.1453947686440656,"score_gpt":0.4709870912659708,"score_spread":0.32559232262190524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155658952","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000572693,0.97568023,0.000216448,0.00004187874,0.020830419,0.002597431,0.00035918894,0.00006657174,0.00015057682],"genre_scores_gemma":[0.00001937449,0.9928635,0.0003174096,0.00011626288,0.0036011788,0.0015273507,0.001359414,0.00009562927,0.000099910496],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974106,0.00015948802,0.0008764261,0.0008095494,0.0001167609,0.0006271984],"domain_scores_gemma":[0.9984984,0.00032730613,0.0004917083,0.00046612613,0.00009239343,0.00012406087],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023978243,0.0005845512,0.0019672962,0.00018451463,0.00007779058,0.000014196647,0.00031662735,0.00080954056,0.0006511745],"category_scores_gemma":[0.000027569307,0.00042488112,0.0006424014,0.0002634819,0.00017746113,0.000044720036,0.000058552665,0.0009492404,0.00006130719],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006840016,0.0003634297,0.000026001075,0.0143862795,0.000092038164,0.0000010046051,0.000074519885,7.543606e-7,0.00036794675,0.0002425582,0.004266619,0.98011047],"study_design_scores_gemma":[0.0016338575,0.00019656982,0.0000047593244,0.0050282623,0.00012948422,0.000002261237,0.000005031089,0.000023770064,0.00068390276,0.00026250916,0.99162173,0.00040786396],"about_ca_topic_score_codex":0.000021657994,"about_ca_topic_score_gemma":6.024485e-7,"teacher_disagreement_score":0.9873551,"about_ca_system_score_codex":0.00013124922,"about_ca_system_score_gemma":0.0008249871,"threshold_uncertainty_score":0.9998203},"labels":[],"label_agreement":null},{"id":"W2155835417","doi":"10.1242/jcs.02324","title":"The lipid composition of autophagic vacuoles regulates expression of multilamellar bodies","year":2005,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; Université de Montréal; University of British Columbia","funders":"","keywords":"Biology; Autophagy; Vacuole; Cell biology; Composition (language); Lipid droplet; Biochemistry; Cytoplasm; Apoptosis","score_opus":0.008818771631990168,"score_gpt":0.27471999525648155,"score_spread":0.26590122362449137,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155835417","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953866,0.003305563,0.000103985876,0.00040513332,0.000115905226,0.000064751504,9.2297813e-7,0.0000037607113,0.0006133488],"genre_scores_gemma":[0.9964049,0.0006044542,0.0026164153,0.000054493008,0.00013868956,2.9999435e-7,1.7213036e-7,0.0000036980653,0.00017689056],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988357,0.000031681087,0.00039041048,0.00007223645,0.00054504024,0.0001249714],"domain_scores_gemma":[0.9988203,0.00010721062,0.00051387097,0.00016273894,0.00030742644,0.000088423396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00065624213,0.00006429098,0.00018964571,0.000095817966,0.00012641925,0.000012004082,0.00023278756,0.000027152275,0.000034529847],"category_scores_gemma":[0.000043438424,0.000035089033,0.00010160231,0.00013603337,0.00050457177,0.00018889531,0.000028612554,0.00009347245,0.0000018889123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016523316,0.00015896713,0.00044366374,0.00002452226,0.0000065022223,0.0000038667667,0.00045982312,0.00015046199,0.99522555,0.000037930993,0.00017297074,0.0031505132],"study_design_scores_gemma":[0.00059315044,0.00025194063,0.01652403,0.00020339507,0.000030084808,0.000028480521,0.00014860372,0.0007866308,0.98059475,0.0001680004,0.00063814456,0.00003279966],"about_ca_topic_score_codex":0.0000012312602,"about_ca_topic_score_gemma":2.5303072e-7,"teacher_disagreement_score":0.016080366,"about_ca_system_score_codex":0.000029437568,"about_ca_system_score_gemma":0.00014800542,"threshold_uncertainty_score":0.18591157},"labels":[],"label_agreement":null},{"id":"W2157431224","doi":"10.1053/j.gastro.2008.12.002","title":"Glutamine Increases Autophagy Under Basal and Stressed Conditions in Intestinal Epithelial Cells","year":2008,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":130,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Autophagy; PI3K/AKT/mTOR pathway; Cell biology; Glutamine; Kinase; p38 mitogen-activated protein kinases; Biology; Programmed cell death; Protein kinase A; Apoptosis; Chemistry; Signal transduction; Biochemistry","score_opus":0.013822381360234792,"score_gpt":0.25860593074032534,"score_spread":0.24478354938009056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157431224","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99840224,0.00010229436,0.0004951177,0.0005154632,0.000091053815,0.0001791902,0.00006766236,0.00005008191,0.000096895936],"genre_scores_gemma":[0.9961672,0.000101171114,0.00033418433,0.0030260386,0.00012627039,0.000026844671,0.00007419816,0.000016878736,0.00012724838],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99899733,0.000088820656,0.00023588461,0.00024973176,0.00010027841,0.00032794024],"domain_scores_gemma":[0.9994988,0.00007160207,0.000056050463,0.00016861293,0.000034084766,0.00017085395],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005371662,0.00015198147,0.00029741364,0.00015917273,0.000060180308,0.000003805651,0.00006132558,0.00006809176,0.00042785658],"category_scores_gemma":[0.000028187605,0.00014014605,0.00005279984,0.00006972385,0.0003358186,0.00005321425,0.00004190082,0.00017937516,0.000027245516],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0039010032,0.0019789839,0.8387296,0.000058430993,0.00019452017,0.0031755231,0.00025554386,0.00008885894,0.14917323,0.00044827696,0.0017001019,0.0002958958],"study_design_scores_gemma":[0.0055091735,0.0012785849,0.98187625,0.000033432425,0.000046686848,0.0010829972,0.00005441639,0.00032536706,0.009087207,0.0005663294,0.00006966552,0.00006991368],"about_ca_topic_score_codex":0.00012185653,"about_ca_topic_score_gemma":0.00006846116,"teacher_disagreement_score":0.14314659,"about_ca_system_score_codex":0.00003147421,"about_ca_system_score_gemma":0.000057007175,"threshold_uncertainty_score":0.571499},"labels":[],"label_agreement":null},{"id":"W2157766835","doi":"10.1038/sj.cdd.4402099","title":"Regulation of autophagy by the inositol trisphosphate receptor","year":2007,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":298,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; McMaster University Medical Centre","funders":"Institut National Du Cancer; European Commission","keywords":"Autophagy; Cell biology; Endoplasmic reticulum; Thapsigargin; Inositol; Mitochondrion; Biology; Unfolded protein response; ATG12; Receptor; Chemistry; ATG5; Biochemistry; Apoptosis","score_opus":0.008189916754058557,"score_gpt":0.24180418407024679,"score_spread":0.23361426731618823,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157766835","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992225,0.0023575048,0.0038051296,0.000091697046,0.00011959857,0.00023952046,0.00000598294,0.000024196574,0.001131359],"genre_scores_gemma":[0.99779224,0.00023167543,0.000103113045,0.00013829865,0.00006308764,0.000004590119,0.0001274543,0.000008292978,0.001531263],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994203,0.000019089515,0.00019103244,0.00011393892,0.00014271005,0.00011293382],"domain_scores_gemma":[0.99959475,0.000048060192,0.00010658614,0.0001331972,0.000045486897,0.00007193363],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118924654,0.00007993622,0.00012058101,0.00003684185,0.00006592923,0.000009455609,0.00003158148,0.00006577812,0.00016309289],"category_scores_gemma":[0.000010769631,0.000053362462,0.000046000092,0.00007500094,0.000027087433,0.0000480282,0.000008821701,0.000055256223,0.000006594622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000989339,0.0004777479,0.06911708,0.0001652778,0.00008459045,0.000001882977,0.0007511865,0.0000012379121,0.86617595,0.0023083868,0.0047099437,0.0552174],"study_design_scores_gemma":[0.00096042984,0.00007813073,0.46707165,0.0000128448755,0.000058329817,0.0000011594495,0.000028249868,0.00027830483,0.530216,0.00030770656,0.00094697543,0.00004027469],"about_ca_topic_score_codex":0.000016058451,"about_ca_topic_score_gemma":6.5944e-7,"teacher_disagreement_score":0.39795455,"about_ca_system_score_codex":0.00001630542,"about_ca_system_score_gemma":0.000015022241,"threshold_uncertainty_score":0.21760581},"labels":[],"label_agreement":null},{"id":"W2157793962","doi":"10.4161/auto.24406","title":"Host and bacterial factors that regulate LC3 recruitment to <i> <i>Listeria monocytogenes</i> </i> during the early stages of macrophage infection","year":2013,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":123,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Phagosome; Biology; Listeria monocytogenes; Microbiology; NADPH oxidase; Bacteria; Phagocytosis; Intracellular parasite; Cell biology; Intracellular; Reactive oxygen species","score_opus":0.038312859703173226,"score_gpt":0.2830093350931767,"score_spread":0.2446964753900035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157793962","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99712455,0.0003703411,0.000015887748,0.00023952658,0.00043982314,0.0015035076,0.000032469503,0.00008443258,0.00018943979],"genre_scores_gemma":[0.9974714,0.00022507511,0.00007182976,0.00036715082,0.00014687725,0.0001631114,0.000016222803,0.000040586132,0.0014977528],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998754,0.00007956158,0.000303479,0.0003165755,0.00023927426,0.00030709093],"domain_scores_gemma":[0.9990501,0.000048565933,0.00014456642,0.00047644338,0.000067896544,0.00021243715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000104877305,0.0002460983,0.00035306273,0.00008904759,0.00014520384,0.00007106917,0.00010579227,0.00010674798,0.0006777642],"category_scores_gemma":[0.000017373619,0.00016714605,0.00011169323,0.00015215408,0.000098465986,0.00019577211,0.00010892623,0.000110261,0.000053807824],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037029677,0.000108851644,0.07008334,0.00011741557,0.00017125507,0.000022404914,0.0012328112,0.0000025528993,0.9247234,0.00004659405,0.00019543081,0.0029256884],"study_design_scores_gemma":[0.0007656084,0.00020271592,0.55504763,0.00003627503,0.000042792555,0.000010536313,0.000032851058,0.0000026860703,0.4420553,0.000029291883,0.0016817563,0.00009252884],"about_ca_topic_score_codex":0.00089163997,"about_ca_topic_score_gemma":0.000012030703,"teacher_disagreement_score":0.4849643,"about_ca_system_score_codex":0.000063542066,"about_ca_system_score_gemma":0.000035046905,"threshold_uncertainty_score":0.7421043},"labels":[],"label_agreement":null},{"id":"W2158609694","doi":"10.1073/pnas.1406425111","title":"Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak","year":2014,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":194,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Programmed cell death; Bcl-2 family; Cell biology; Apoptosis; Biology; Bcl-2-associated X protein; Cancer research; Caspase 3; Biochemistry","score_opus":0.02429291860670312,"score_gpt":0.30599192979776263,"score_spread":0.2816990111910595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158609694","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9813412,0.0006299089,8.5341793e-7,0.00138951,0.000020816244,0.00024590283,0.000010493307,0.00002493344,0.016336408],"genre_scores_gemma":[0.9981457,0.000055145316,0.00040452112,0.0008493667,0.0001067603,0.0000086567525,3.3072178e-7,0.0000069105995,0.0004226249],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982213,0.0000118944545,0.00027899037,0.00026417556,0.0010477237,0.00017592801],"domain_scores_gemma":[0.99930537,0.00016221107,0.00030137188,0.000007658813,0.00014685073,0.00007654895],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015153139,0.00011710498,0.0002288504,0.00012953451,0.00018833777,0.00002959681,0.0002708091,0.00009092771,0.000012339949],"category_scores_gemma":[0.0005056659,0.00007629624,0.00007314082,0.0004684844,0.0007620089,0.00036945273,0.00008408032,0.00016990636,9.3031707e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061038845,0.00011448302,0.02482297,0.00020514752,0.00004392155,2.15659e-8,0.00031447544,0.0000032079624,0.93900025,0.029357959,0.0018676991,0.004208804],"study_design_scores_gemma":[0.0008697751,0.00023067745,0.24843478,0.0003008283,0.00004505314,0.00002539939,0.00021403626,0.0011448534,0.73439527,0.013359255,0.0008440942,0.00013599642],"about_ca_topic_score_codex":0.000009258266,"about_ca_topic_score_gemma":4.1040234e-8,"teacher_disagreement_score":0.2236118,"about_ca_system_score_codex":0.00002488467,"about_ca_system_score_gemma":0.000056020337,"threshold_uncertainty_score":0.31112704},"labels":[],"label_agreement":null},{"id":"W2158955508","doi":"10.1007/s11906-012-0304-5","title":"Striking a Balance: Autophagy, Apoptosis, and Necrosis in a Normal and Failing Heart","year":2012,"lang":"en","type":"review","venue":"Current Hypertension Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital; University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Heart failure; Programmed cell death; Medicine; Apoptosis; Necrosis; Necroptosis; Signal transduction; Disease; Cell biology; Tumor necrosis factor alpha; Bioinformatics; Cancer research; Immunology; Internal medicine; Biology; Genetics","score_opus":0.07294881863078911,"score_gpt":0.3497059918246112,"score_spread":0.2767571731938221,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158955508","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.048550423,0.94949627,0.000003162013,0.000030863583,0.00088430144,0.0009174861,0.0000076804035,0.00007001214,0.000039790317],"genre_scores_gemma":[0.020162635,0.9789402,0.00012196474,0.000119650875,0.00032095553,0.00009166772,0.00013432764,0.00006237169,0.0000462555],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99744624,0.0000877319,0.00096204213,0.00069364626,0.0003322874,0.00047802937],"domain_scores_gemma":[0.99853545,0.00009025117,0.00041224752,0.0005015069,0.00007125628,0.00038928722],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043352,0.00049906276,0.0020726104,0.00031063284,0.00010124756,0.00004767698,0.000044533997,0.0003152691,0.00005008418],"category_scores_gemma":[0.00009053001,0.00038259017,0.0002832316,0.0002739952,0.000091427675,0.00014029819,0.00013893886,0.00062310294,0.0000036626973],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016300448,0.00023314846,0.0029228437,0.010167703,0.000086671935,0.00047228002,0.000052288662,6.539067e-8,0.000041077616,0.00000555369,0.00036262584,0.98563945],"study_design_scores_gemma":[0.0005381938,0.00005363269,0.002421195,0.022227999,0.001435766,0.0059268754,0.000014241637,0.00003528821,0.000032413733,0.0000193664,0.9668849,0.00041013738],"about_ca_topic_score_codex":0.000018178416,"about_ca_topic_score_gemma":5.6682654e-7,"teacher_disagreement_score":0.9852293,"about_ca_system_score_codex":0.00006857652,"about_ca_system_score_gemma":0.00025310964,"threshold_uncertainty_score":0.9998626},"labels":[],"label_agreement":null},{"id":"W2159212772","doi":"10.1016/s1534-5807(03)00269-7","title":"Shaping and Stretching Life by Autophagy","year":2003,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Biology; Autophagy; Cell biology; Genetics; Apoptosis","score_opus":0.015363944929172374,"score_gpt":0.23695707724475107,"score_spread":0.2215931323155787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159212772","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9646658,0.0028135555,0.00005412937,0.000058572077,0.00007161172,0.0001328571,0.0000039358524,0.00005476842,0.032144774],"genre_scores_gemma":[0.99343985,0.00013826664,0.002350372,0.0021294958,0.000019687332,0.000007656476,0.000024184357,0.000019236293,0.0018712541],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993128,0.000019417783,0.00014785286,0.00019339292,0.00013487581,0.00019165436],"domain_scores_gemma":[0.99965024,0.000019173624,0.000030427818,0.00006912692,0.00001141665,0.00021960061],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000081226644,0.0001205985,0.00014428637,0.00003783352,0.000091542795,0.00001804172,0.00003353532,0.00005010833,0.0005486232],"category_scores_gemma":[0.000018498264,0.000111689405,0.000027937533,0.00006996355,0.000030455321,0.000060026367,0.000018178149,0.00009677477,0.00007397798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041220797,0.0019857015,0.20063528,0.0009598201,0.00080696726,0.00090565096,0.011644601,0.000003570171,0.6532106,0.004152807,0.077968664,0.047314145],"study_design_scores_gemma":[0.0048124935,0.00014462085,0.038480856,0.000104903585,0.00006570182,0.00015117245,0.0018255593,0.00010717514,0.8566831,0.00045337365,0.09662238,0.00054868485],"about_ca_topic_score_codex":0.0000060371353,"about_ca_topic_score_gemma":3.4479038e-7,"teacher_disagreement_score":0.2034725,"about_ca_system_score_codex":0.000045876768,"about_ca_system_score_gemma":0.00013738898,"threshold_uncertainty_score":0.60070395},"labels":[],"label_agreement":null},{"id":"W2160936581","doi":"10.4161/auto.4450","title":"<i>Listeria monocytogenes</i>Evades Killing by Autophagy During Colonization of Host Cells","year":2007,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":247,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Howard Hughes Medical Institute","keywords":"Autophagy; Listeria monocytogenes; Biology; Intracellular parasite; Microbiology; Vacuole; Phagosome; Intracellular; Cytosol; Bacteria; Innate immune system; Virulence; Cell biology; Pathogen; Population; Immune system; Gene; Cytoplasm; Immunology; Biochemistry; Enzyme; Apoptosis; Genetics","score_opus":0.010592857589465161,"score_gpt":0.27222010179595185,"score_spread":0.2616272442064867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2160936581","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925606,0.0028564816,0.0021807349,0.00007088086,0.00047133813,0.00043667413,0.000041412048,0.00018923519,0.001192599],"genre_scores_gemma":[0.9959278,0.00032044828,0.0007653461,0.00048599974,0.00023885752,0.00001363267,0.000079371835,0.000068780115,0.002099764],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99804986,0.000040865965,0.0006390126,0.00040179593,0.00037612708,0.00049233134],"domain_scores_gemma":[0.9987882,0.00008601131,0.0002639531,0.00046271877,0.00015423018,0.00024488854],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028565686,0.00027868888,0.00048736818,0.00017916264,0.00013399508,0.000021820924,0.00017548446,0.0002131271,0.00046405697],"category_scores_gemma":[0.000028386754,0.0002745839,0.00017092399,0.00039358,0.00012401122,0.00014778336,0.00005729085,0.0001559843,0.00006616071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045731693,0.0003134702,0.0019816626,0.00019456459,0.0001322059,0.00015140127,0.00043730944,0.000021311133,0.99404985,0.00016154844,0.00035256858,0.0017468089],"study_design_scores_gemma":[0.002098709,0.0002090206,0.05165433,0.000088951645,0.00010428253,0.00004162836,0.00010367014,0.00022795932,0.9421603,0.00006217303,0.003026942,0.00022201834],"about_ca_topic_score_codex":0.00005697584,"about_ca_topic_score_gemma":0.0000035669511,"teacher_disagreement_score":0.051889516,"about_ca_system_score_codex":0.000117186864,"about_ca_system_score_gemma":0.000102400554,"threshold_uncertainty_score":0.9999706},"labels":[],"label_agreement":null},{"id":"W2161824090","doi":"10.1095/biolreprod.112.106617","title":"Cigarette Smoke Exposure Elicits Increased Autophagy and Dysregulation of Mitochondrial Dynamics in Murine Granulosa Cells1","year":2013,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; BECN1; Cell biology; Biology; Western blot; Programmed cell death; Apoptosis; Andrology; Medicine; Biochemistry; Gene","score_opus":0.009519510993883389,"score_gpt":0.24964033514971914,"score_spread":0.24012082415583574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2161824090","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99621224,0.0022066175,0.00008466973,0.00050911016,0.00034221882,0.00050379755,0.0000101304295,0.00002727965,0.00010391061],"genre_scores_gemma":[0.9987105,0.00024427642,0.0004709142,0.000028311832,0.00025629654,0.000023505958,0.00015341083,0.000010389094,0.00010239643],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990127,0.000078996454,0.00035885433,0.0003424085,0.00008453856,0.0001224832],"domain_scores_gemma":[0.9992483,0.000028064938,0.00019171774,0.00035397775,0.00013215945,0.000045763696],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015395548,0.000109828914,0.00030670807,0.00017249757,0.000020488596,0.0000019541937,0.00003980988,0.00016712167,0.00007972264],"category_scores_gemma":[0.000113406335,0.00009696289,0.000049820916,0.00015335613,0.00018188532,0.00007068214,0.000018120529,0.00009369646,0.000001692559],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010473221,0.00050322135,0.29164565,0.00025195035,0.00016858635,0.0000051519746,0.0002748006,0.000014994307,0.6250451,0.001187386,0.00016371867,0.07969214],"study_design_scores_gemma":[0.002080237,0.0005306384,0.742717,0.00005009196,0.00004986369,0.000024541776,0.00006375804,0.00059955736,0.25192288,0.0017404293,0.00013436764,0.00008661612],"about_ca_topic_score_codex":0.00074713473,"about_ca_topic_score_gemma":0.00001948043,"teacher_disagreement_score":0.45107138,"about_ca_system_score_codex":0.000040880972,"about_ca_system_score_gemma":0.00003553075,"threshold_uncertainty_score":0.3954032},"labels":[],"label_agreement":null},{"id":"W2164778558","doi":"10.4161/auto.19496","title":"Guidelines for the use and interpretation of assays for monitoring autophagy","year":2012,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4046,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique; Montreal Neurological Institute and Hospital; Hospital for Sick Children","funders":"National Institute on Minority Health and Health Disparities; National Center for Advancing Translational Sciences; National Institute of Dental and Craniofacial Research; National Institute of Mental Health; National Heart, Lung, and Blood Institute; National Institute on Alcohol Abuse and Alcoholism; National Eye Institute; National Center for Complementary and Integrative Health; National Institute for Health and Care Research; National Institute on Aging; National Cancer Institute; Natural Environment Research Council; National Institute of Diabetes and Digestive and Kidney Diseases; Wellcome Trust; Cancer Research UK; Biotechnology and Biological Sciences Research Council; National Center for Research Resources; Versus Arthritis; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute; Novo Nordisk Fonden; Brain Tumour Charity; Parkinson's UK; U.S. Department of Veterans Affairs; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institutes of Health; Sight Research UK","keywords":"Autophagy; Autophagosome; Biology; Cell biology; Multicellular organism; Phagosome; ATG8; Biogenesis; Vacuole; Intracellular; Cell; Biochemistry; Cytoplasm; Gene","score_opus":0.16171936672965026,"score_gpt":0.402170421926909,"score_spread":0.24045105519725873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2164778558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91244316,0.013989527,0.06972391,0.00087005907,0.001198526,0.0015601246,0.000054501586,0.00009123327,0.00006896761],"genre_scores_gemma":[0.98580396,0.00023970765,0.011676285,0.0005767026,0.00075442536,0.0002319516,0.00001589646,0.00003093529,0.00067014113],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912167,0.000020226315,0.00033073578,0.00014523361,0.00013464269,0.00024748727],"domain_scores_gemma":[0.9984368,0.0007330259,0.00012832909,0.00025296124,0.0003517474,0.000097117896],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034843344,0.00013341838,0.0002462508,0.00005657722,0.00009597315,0.000019743386,0.00007538905,0.00007771522,0.000018550976],"category_scores_gemma":[0.0007558641,0.00008995101,0.0001426507,0.00006917823,0.00006288241,0.00024553592,0.000024480372,0.000055996104,0.0000021804387],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036052715,0.00087252696,0.036152426,0.0013415599,0.0019985558,0.0000062905706,0.006344079,0.00026751243,0.13500936,0.022589192,0.016730892,0.77508235],"study_design_scores_gemma":[0.0071136756,0.00094175525,0.28221515,0.00038917887,0.0012876805,0.00005599829,0.0006107858,0.08592693,0.5533477,0.0022089167,0.06546565,0.00043658668],"about_ca_topic_score_codex":0.000020420965,"about_ca_topic_score_gemma":5.332496e-7,"teacher_disagreement_score":0.77464575,"about_ca_system_score_codex":0.00002280149,"about_ca_system_score_gemma":0.000042793657,"threshold_uncertainty_score":0.3668096},"labels":[],"label_agreement":null},{"id":"W2165822680","doi":"10.1152/ajpcell.00240.2012","title":"Adaptive plasticity of autophagic proteins to denervation in aging skeletal muscle","year":2012,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":163,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Autophagy; Denervation; Mitophagy; Biology; Endocrinology; Skeletal muscle; Cell biology; Internal medicine; Lysosome; Mitochondrion; Parkin; Proteostasis; Ageing; Protein turnover; Apoptosis; Biochemistry; Medicine; Protein biosynthesis; Parkinson's disease; Genetics","score_opus":0.012903233120483115,"score_gpt":0.2700490243318135,"score_spread":0.25714579121133035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2165822680","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99869704,0.00025493006,0.0003402494,0.00015295827,0.00017347359,0.00025272442,0.000006304289,0.000012132243,0.000110167966],"genre_scores_gemma":[0.9964026,0.00004019518,0.0022078452,0.00078238896,0.00050446845,0.000014544171,0.0000058532924,0.000024021207,0.000018064511],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983044,0.0002585136,0.0006032906,0.00020639945,0.00017442057,0.00045292094],"domain_scores_gemma":[0.9984509,0.0001852596,0.0007375125,0.0001960555,0.00018806383,0.00024226164],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021214182,0.00020947418,0.0008772465,0.00029629213,0.00003632077,0.0000016492347,0.00018299223,0.00007294863,0.00011191755],"category_scores_gemma":[0.00007738371,0.00017010387,0.00021371899,0.00044159577,0.00038112272,0.00015119904,0.000058915302,0.00035993205,0.000022975602],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007884086,0.00090649544,0.00090784056,0.0000383598,0.000102208054,0.000006306608,0.0007817083,0.00079467945,0.99201775,0.00010829238,0.00007127138,0.0034767091],"study_design_scores_gemma":[0.0016087309,0.0040512066,0.86491966,0.0000934106,0.00007899034,0.000019517754,0.00066667894,0.00018994736,0.12746383,0.0005558122,0.00018639343,0.00016582107],"about_ca_topic_score_codex":0.00008301363,"about_ca_topic_score_gemma":0.0000020342713,"teacher_disagreement_score":0.86455387,"about_ca_system_score_codex":0.00008900544,"about_ca_system_score_gemma":0.00016215371,"threshold_uncertainty_score":0.6936634},"labels":[],"label_agreement":null},{"id":"W2167109421","doi":"10.1073/pnas.0707460104","title":"Presecretory oxidation, aggregation, and autophagic destruction of apoprotein-B: A pathway for late-stage quality control","year":2008,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":129,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Apolipoprotein B; Proteolysis; Secretion; Chemistry; Golgi apparatus; Autophagy; Reactive oxygen species; Biochemistry; Cell biology; Polyunsaturated fatty acid; Enzyme; Biology; Cholesterol; Fatty acid; Endoplasmic reticulum","score_opus":0.05767383338058076,"score_gpt":0.33145206178660425,"score_spread":0.2737782284060235,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167109421","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99762696,0.0003597432,0.00003815499,0.0010122636,0.000012712586,0.0005640725,0.000035079167,0.0000112999105,0.00033973268],"genre_scores_gemma":[0.998238,0.000049394155,0.0011492468,0.00016886457,0.000052086034,0.000032675936,7.5534706e-7,0.0000037806924,0.0003051436],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99864876,0.000009008722,0.00037725997,0.00017357255,0.00069954636,0.00009184327],"domain_scores_gemma":[0.9986963,0.00013317559,0.0005795338,0.000010787392,0.0005404989,0.00003965427],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009618485,0.00007407997,0.00019537144,0.00011278936,0.00017051876,0.00000468904,0.00016885578,0.00007380547,0.00001404149],"category_scores_gemma":[0.00079735095,0.000051033956,0.00007504347,0.00029098627,0.00087621267,0.0002943596,0.00002020374,0.000070721246,2.1235587e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003368577,0.000115513896,0.03093555,0.00046360973,0.00006910106,1.3603233e-8,0.0004977096,0.000070993556,0.9073251,0.05900032,0.0001193037,0.001065941],"study_design_scores_gemma":[0.0011368718,0.00011962981,0.29292566,0.00008790634,0.00002109418,0.0000059113363,0.000073691524,0.0015304416,0.6747702,0.02918684,0.000089698064,0.00005208284],"about_ca_topic_score_codex":0.0000072770495,"about_ca_topic_score_gemma":2.5772898e-8,"teacher_disagreement_score":0.2619901,"about_ca_system_score_codex":0.000020689691,"about_ca_system_score_gemma":0.00009163185,"threshold_uncertainty_score":0.3228442},"labels":[],"label_agreement":null},{"id":"W2167430243","doi":"10.1074/jbc.m413934200","title":"Essential Roles of Atg5 and FADD in Autophagic Cell Death","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":531,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Harvard University","keywords":"FADD; Autophagy; ATG5; Cell biology; Programmed cell death; Biology; Apoptosis; Genetics; Caspase","score_opus":0.01426310633058761,"score_gpt":0.27447069850487654,"score_spread":0.2602075921742889,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167430243","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99407995,0.0044350447,0.000015069325,0.000211484,0.000013592809,0.000030748153,0.0000030013232,0.0000046640434,0.0012064185],"genre_scores_gemma":[0.99822354,0.0007976391,0.00045040858,0.00012627605,0.00027886633,5.520467e-7,0.0000022701083,0.000003711593,0.00011671625],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993421,0.000014918438,0.00033618056,0.00008562977,0.000110364046,0.00011079832],"domain_scores_gemma":[0.9995532,0.00004061282,0.00018170573,0.00007067627,0.000045418205,0.00010840571],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013225724,0.00008307178,0.0002862103,0.0000229128,0.00001029703,0.000003614215,0.00006980661,0.00013089283,0.00035941912],"category_scores_gemma":[0.000041867075,0.000052686308,0.00010097008,0.00004614644,0.00007118473,0.000028150102,0.000021014412,0.0002013923,0.0000014248446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041738886,0.00045240173,0.036404505,0.00006378809,0.000034350054,0.00015620349,0.00005860962,0.000008241167,0.9599044,0.000009353175,0.000060408016,0.002430402],"study_design_scores_gemma":[0.0018312603,0.0002052965,0.06884261,0.00007021623,0.000031694704,0.00020377275,0.00007279974,0.00005653743,0.9278631,0.00023328362,0.0005273845,0.00006204381],"about_ca_topic_score_codex":8.5104455e-7,"about_ca_topic_score_gemma":1.3820934e-7,"teacher_disagreement_score":0.03243811,"about_ca_system_score_codex":0.000022147724,"about_ca_system_score_gemma":0.00004752541,"threshold_uncertainty_score":0.39353874},"labels":[],"label_agreement":null},{"id":"W2167806126","doi":"10.2174/1566524014666140603101520","title":"Autophagy and Heart Disease: Implications for Cardiac Ischemia- Reperfusion Damage","year":2014,"lang":"en","type":"review","venue":"Current Molecular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Autophagy; Mitophagy; Ischemia; Context (archaeology); Cell biology; Homeostasis; Reperfusion injury; Mesenchymal stem cell; Biology; Medicine; Intracellular; Cardiology; Biochemistry","score_opus":0.04501067270880824,"score_gpt":0.40849593390731764,"score_spread":0.3634852611985094,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167806126","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00023500108,0.9927969,0.0015853696,0.0012993704,0.00069314503,0.00289066,0.00018065558,0.00012151781,0.00019740927],"genre_scores_gemma":[0.00016793114,0.99354064,0.00015232796,0.00064801617,0.00121604,0.00093391706,0.0030067945,0.00012735077,0.00020695828],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975931,0.000134964,0.0007185661,0.00084128336,0.00031209277,0.0003999785],"domain_scores_gemma":[0.99734706,0.00020395566,0.00028169304,0.0012207415,0.0001616601,0.00078487245],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003632327,0.0005926232,0.0023714856,0.00023838869,0.00013772339,0.0000152222565,0.00018582097,0.00022871586,0.00006919991],"category_scores_gemma":[0.00042341006,0.0004329503,0.0006928327,0.00027166726,0.00024746815,0.00003261321,0.000096572854,0.00041447236,0.000021397493],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003908358,0.00015538289,0.000025299976,0.03634726,0.00029136727,0.000016990754,0.000026812759,6.215659e-8,0.00084676075,0.002642673,0.01990467,0.93970364],"study_design_scores_gemma":[0.0010377548,0.00018264833,0.00027250938,0.018415067,0.0054835873,0.000025034113,0.000002643516,0.000009590544,0.00005262195,0.00035085002,0.97382337,0.00034435128],"about_ca_topic_score_codex":0.0000018445915,"about_ca_topic_score_gemma":3.524351e-8,"teacher_disagreement_score":0.9539187,"about_ca_system_score_codex":0.00008565546,"about_ca_system_score_gemma":0.0004955521,"threshold_uncertainty_score":0.99981225},"labels":[],"label_agreement":null},{"id":"W2168125601","doi":"10.1242/dev.02332","title":"Autophagy occurs upstream or parallel to the apoptosome during histolytic cell death","year":2006,"lang":"en","type":"article","venue":"Development","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Genome British Columbia","funders":"National Institute of General Medical Sciences; National Institutes of Health; Vedecká Grantová Agentúra MŠVVaŠ SR a SAV","keywords":"Biology; Apoptosome; Autophagy; Programmed cell death; Cell biology; Effector; Apoptosis; Caspase; Regulator; Genetics; Gene","score_opus":0.01466899680383033,"score_gpt":0.2518629277515841,"score_spread":0.23719393094775376,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168125601","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99207324,0.00046907872,0.0003289298,0.00083591114,0.00018143558,0.0005414963,0.000003472559,0.00012922697,0.0054372223],"genre_scores_gemma":[0.96174824,0.00002148603,0.00460009,0.0012897521,0.00019111334,0.00013717574,0.000029685658,0.000030783744,0.031951655],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998689,0.000019144753,0.0003040811,0.00028679782,0.00031680602,0.00038415258],"domain_scores_gemma":[0.99935913,0.00002742157,0.00005944689,0.00034555435,0.000038983424,0.00016943777],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000094033974,0.00020661265,0.000225738,0.000088013876,0.00020247935,0.000021123067,0.00017027927,0.000056839715,0.00044569655],"category_scores_gemma":[0.0000106902935,0.00012630265,0.00006904175,0.00017196496,0.000022452126,0.000034074346,0.00005431657,0.0001088791,0.00065138226],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.020602768,0.019652626,0.31343764,0.0038383203,0.0037979123,0.014269527,0.05222966,0.0070034717,0.11361691,0.014644084,0.27839997,0.1585071],"study_design_scores_gemma":[0.002962921,0.0001380244,0.67283744,0.00010947605,0.000080537895,0.00008413558,0.000154266,0.00004339834,0.13838314,0.00015546138,0.18463632,0.00041490354],"about_ca_topic_score_codex":0.000036166683,"about_ca_topic_score_gemma":0.000015992671,"teacher_disagreement_score":0.35939977,"about_ca_system_score_codex":0.00027721113,"about_ca_system_score_gemma":0.00035008232,"threshold_uncertainty_score":0.8372418},"labels":[],"label_agreement":null},{"id":"W2169090369","doi":"10.1002/yea.3075","title":"Expression of<i>Malus xiaojinensis</i>IRT1 (MxIRT1) protein in transgenic yeast cells leads to degradation through autophagy in the presence of excessive iron","year":2015,"lang":"en","type":"article","venue":"Yeast","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"National Natural Science Foundation of China; National Science Foundation","keywords":"Biology; Autophagy; Yeast; Transgene; Cell biology; Degradation (telecommunications); Protein degradation; Genetically modified mouse; Malus; Genetics; Gene; Botany; Apoptosis","score_opus":0.030314294320286116,"score_gpt":0.29467066409635334,"score_spread":0.26435636977606725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169090369","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962655,0.00051317806,0.0003777479,0.00031122094,0.00009145459,0.0011277715,0.00002784072,0.00001666676,0.0012686306],"genre_scores_gemma":[0.99850065,0.000021256028,0.00061938725,0.00017219622,0.00007119148,0.00010712835,0.000018519002,0.00001975033,0.00046992078],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984472,0.00015927118,0.00041456296,0.00025838008,0.0004914634,0.00022913552],"domain_scores_gemma":[0.99920386,0.000035021927,0.00014013705,0.00042966128,0.00009386181,0.00009747183],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032267463,0.00016040627,0.0003365476,0.00010742517,0.000019914338,0.000007988685,0.00022775264,0.00009902399,0.000060274484],"category_scores_gemma":[0.0000832354,0.00011457529,0.00007800742,0.00045586037,0.00009282409,0.0001524765,0.000030159157,0.00017558665,0.000018859913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001134963,0.0006803089,0.0018427672,0.00020587217,0.000011124356,0.000053904634,0.010663007,0.00029046007,0.98228276,0.00017608557,0.00072719326,0.0019315786],"study_design_scores_gemma":[0.0026893544,0.00039391164,0.020794922,0.0006692344,0.000030370891,0.0000068680815,0.0016075348,0.00013575857,0.9728075,0.00031794768,0.00041540663,0.00013113573],"about_ca_topic_score_codex":0.0002552961,"about_ca_topic_score_gemma":0.000054634434,"teacher_disagreement_score":0.018952155,"about_ca_system_score_codex":0.000048324255,"about_ca_system_score_gemma":0.00017982534,"threshold_uncertainty_score":0.46722448},"labels":[],"label_agreement":null},{"id":"W2169512179","doi":"10.1152/ajpcell.00451.2011","title":"Denervation-induced mitochondrial dysfunction and autophagy in skeletal muscle of apoptosis-deficient animals","year":2012,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Autophagy; Denervation; Mitophagy; Skeletal muscle; Cell biology; Biology; Apoptosis; Endocrinology; Internal medicine; Mitochondrion; Muscle atrophy; Mitochondrial biogenesis; Biochemistry; Medicine","score_opus":0.011635713796081706,"score_gpt":0.2627712770062157,"score_spread":0.251135563210134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169512179","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982235,0.0008052197,0.000030413028,0.00011465941,0.0005631743,0.00017084132,0.0000045552842,0.000010983462,0.00007664964],"genre_scores_gemma":[0.99808997,0.0001850256,0.00058924337,0.0003757003,0.0007052532,0.000009365853,0.000009858696,0.000023235581,0.0000123189675],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99826354,0.00026004188,0.0006739927,0.00022965315,0.00017432784,0.00039847306],"domain_scores_gemma":[0.99837077,0.00018126593,0.0008623623,0.0002358607,0.00015963444,0.00019012351],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020034828,0.0002159809,0.000897455,0.00026661204,0.00004426001,0.0000028215684,0.00012482656,0.00010851349,0.00011314595],"category_scores_gemma":[0.00006080181,0.00017434415,0.00021129608,0.00030421765,0.00041285407,0.00013694575,0.000046376237,0.00031706633,0.000008671888],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007704501,0.00078333163,0.0008364855,0.000043765114,0.000101313366,0.000001663125,0.00037700761,0.00006172746,0.99312925,0.00011918823,0.000103066595,0.0036727688],"study_design_scores_gemma":[0.0030394532,0.004073728,0.69195473,0.000048036763,0.0001300346,0.000034007746,0.0006371148,0.000078247744,0.29904294,0.00047411764,0.00031742902,0.00017016295],"about_ca_topic_score_codex":0.000062133266,"about_ca_topic_score_gemma":9.07192e-7,"teacher_disagreement_score":0.6940863,"about_ca_system_score_codex":0.000057908157,"about_ca_system_score_gemma":0.00012574777,"threshold_uncertainty_score":0.71095484},"labels":[],"label_agreement":null},{"id":"W2169536980","doi":"10.1164/rccm.201304-0732oc","title":"Autophagy in Locomotor Muscles of Patients with Chronic Obstructive Pulmonary Disease","year":2013,"lang":"en","type":"article","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":114,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Christie (Canada); McGill University; Jewish General Hospital; McGill University Health Centre; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"Canadian Institutes of Health Research; Helsingin Yliopisto","keywords":"Autophagy; AMPK; Medicine; ATG12; mTORC1; BECN1; Protein degradation; Protein kinase B; FOXO3; Endocrinology; Internal medicine; Cell biology; Biology; Protein kinase A; Signal transduction; Phosphorylation; ATG5; Biochemistry","score_opus":0.007664089681772647,"score_gpt":0.27203525269684364,"score_spread":0.264371163015071,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169536980","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896747,0.009279373,0.00004472506,0.00055501715,0.00006687479,0.00023497826,0.000009927436,0.0000061595397,0.00012823576],"genre_scores_gemma":[0.99862427,0.000059079768,0.00010558706,0.0009406326,0.00023402514,0.000011171391,0.000003430663,0.00001711732,0.000004664467],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986135,0.00011755649,0.00046594738,0.00016268027,0.00043139036,0.00020897035],"domain_scores_gemma":[0.99832773,0.00019348368,0.00019029112,0.00017216514,0.0005914286,0.0005249068],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010897666,0.0001604577,0.0005764623,0.00020143075,0.000032101692,0.000004310492,0.000086273685,0.000031417785,0.00025602998],"category_scores_gemma":[0.00024099466,0.00010126372,0.00006693827,0.00022998177,0.0015335396,0.0001657056,0.000018354738,0.00025691028,0.000001227186],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023636525,0.0004421852,0.7557493,0.00055656553,0.00008638522,0.00080957764,0.0007605883,0.0000027114518,0.0010967475,0.00032365747,0.000052689727,0.23775597],"study_design_scores_gemma":[0.0023482668,0.007024923,0.9864536,0.0006364097,0.0001803296,0.00001997643,0.0022932237,0.000007702111,0.00028511076,0.00024264424,0.00040608324,0.00010175798],"about_ca_topic_score_codex":0.00002949521,"about_ca_topic_score_gemma":0.0000013608269,"teacher_disagreement_score":0.23765421,"about_ca_system_score_codex":0.00007828548,"about_ca_system_score_gemma":0.00024209362,"threshold_uncertainty_score":0.56503904},"labels":[],"label_agreement":null},{"id":"W2169643027","doi":"10.4161/auto.5594","title":"Avoiding death by autophagy: Interactions of<i>Listeria monocytogenes</i>with the macrophage autophagy system","year":2008,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Autophagy; Biology; Listeria monocytogenes; Macrophage; Cell biology; Programmed cell death; Listeria; Microbiology; Apoptosis; Genetics; Bacteria","score_opus":0.025365502426033283,"score_gpt":0.26543550409036104,"score_spread":0.24007000166432776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169643027","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9809212,0.0059720688,0.0025761852,0.0003805857,0.0006209445,0.0009843508,0.0001295065,0.00047876447,0.0079363575],"genre_scores_gemma":[0.98800915,0.00027570757,0.00060218,0.0010119822,0.00034958855,0.00019657114,0.0000860652,0.00013896417,0.009329788],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996677,0.00034280383,0.0007902864,0.00073105074,0.0007095909,0.0007492982],"domain_scores_gemma":[0.99737555,0.00033105057,0.0004666424,0.0011890562,0.0002518861,0.00038582302],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004160374,0.0006049327,0.00094267033,0.0002169917,0.00095864455,0.000049523762,0.0005130363,0.00020792887,0.0006364961],"category_scores_gemma":[0.00005371638,0.00040858812,0.00041116378,0.0006120821,0.00038149973,0.00030343232,0.00013302463,0.00073260354,0.00026737692],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0043134294,0.0027916,0.00416418,0.0015715593,0.0041561564,0.009295447,0.008239326,0.00034367174,0.8995782,0.014843707,0.037514895,0.013187815],"study_design_scores_gemma":[0.005687228,0.00090398407,0.038961567,0.0004788499,0.00074546534,0.0066931164,0.0012113998,0.0025213503,0.90121526,0.00006372267,0.040713314,0.0008047727],"about_ca_topic_score_codex":0.00020029917,"about_ca_topic_score_gemma":0.000005880578,"teacher_disagreement_score":0.034797385,"about_ca_system_score_codex":0.00030651782,"about_ca_system_score_gemma":0.0003858619,"threshold_uncertainty_score":0.9998366},"labels":[],"label_agreement":null},{"id":"W2169836157","doi":"10.1016/j.ajpath.2012.04.004","title":"AMPK Activation Stimulates Autophagy and Ameliorates Muscular Dystrophy in the mdx Mouse Diaphragm","year":2012,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":224,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Université de Montréal","funders":"Canadian Institutes of Health Research; Association Française contre les Myopathies","keywords":"Mitophagy; AMPK; Duchenne muscular dystrophy; Autophagy; Myocyte; Cell biology; Mitochondrion; mdx mouse; Muscular dystrophy; Biology; AMP-activated protein kinase; Muscle atrophy; Dystrophin; Endocrinology; Internal medicine; Chemistry; Protein kinase A; Skeletal muscle; Apoptosis; Medicine; Kinase; Biochemistry","score_opus":0.009636795269516543,"score_gpt":0.2839685875983422,"score_spread":0.27433179232882565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169836157","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971594,0.0013786324,0.000581543,0.0006692164,0.00006470585,0.00010523722,0.0000021162675,0.000007845075,0.000031303352],"genre_scores_gemma":[0.9971282,0.0003553601,0.00078714616,0.0014433826,0.00025307937,0.000004779684,0.000002541789,0.000013858188,0.000011656501],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99898136,0.00025335638,0.00028645076,0.00008916218,0.00015938171,0.00023027141],"domain_scores_gemma":[0.999211,0.00016407623,0.00029634286,0.00015596062,0.00005839166,0.00011424104],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041956076,0.00011548466,0.00034934754,0.00017950273,0.000039209233,0.000009589337,0.0000904749,0.000042606,0.00003217644],"category_scores_gemma":[0.00009449806,0.000071701055,0.0000813305,0.00023684783,0.00029461714,0.00014702114,0.000014533679,0.00026497143,0.0000043220175],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017457657,0.0017518543,0.30216444,0.000056239223,0.00041182066,0.0026215904,0.017342623,0.00016064839,0.44843936,0.0009391606,0.00020666912,0.2241598],"study_design_scores_gemma":[0.0018860791,0.0018958442,0.9740446,0.000052399046,0.00013845836,0.002231809,0.003879373,0.00006285287,0.014579843,0.0005399545,0.0005481295,0.00014066427],"about_ca_topic_score_codex":0.000018276349,"about_ca_topic_score_gemma":4.1491484e-7,"teacher_disagreement_score":0.6718801,"about_ca_system_score_codex":0.00002550343,"about_ca_system_score_gemma":0.000040151514,"threshold_uncertainty_score":0.2923884},"labels":[],"label_agreement":null},{"id":"W2169923369","doi":"10.1158/1078-0432.ccr-13-2060","title":"Autophagy Inhibition Augments the Anticancer Effects of Epirubicin Treatment in Anthracycline-Sensitive and -Resistant Triple-Negative Breast Cancer","year":2014,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":153,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; University of British Columbia; BC Cancer Agency","funders":"Pfizer; Canadian Institutes of Health Research; Pfizer Canada; Avon Foundation for Women","keywords":"Autophagy; Epirubicin; Anthracycline; Cancer research; Triple-negative breast cancer; Breast cancer; Medicine; Biology; Chemotherapy; Pharmacology; Cancer; Internal medicine; Apoptosis","score_opus":0.0743658566658117,"score_gpt":0.488136597543408,"score_spread":0.4137707408775963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169923369","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911804,0.0021147905,0.000014994759,0.004528296,0.00023645363,0.0015424109,0.000094501374,0.000017882423,0.00027027776],"genre_scores_gemma":[0.98862076,0.00927284,0.00002233312,0.0007396846,0.00048339312,0.000422352,0.000007439584,0.000028889677,0.0004023188],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99663186,0.0010980383,0.00064952386,0.00052577665,0.0006189138,0.0004758589],"domain_scores_gemma":[0.9958112,0.0030725258,0.00015454202,0.0003991767,0.00034344735,0.00021905583],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016083199,0.0002046662,0.00069060375,0.00016199374,0.00014056038,0.000016335654,0.00009499901,0.00015278938,0.0001657323],"category_scores_gemma":[0.0006767069,0.00012578307,0.00015296553,0.00048864196,0.001128371,0.00007434701,0.000078128876,0.00051786576,0.000009439968],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.04067742,0.0069246674,0.2570086,0.0015063761,0.0018328538,0.0006804239,0.0037559257,0.0000384098,0.103565246,0.0017436804,0.0024097764,0.5798566],"study_design_scores_gemma":[0.010435883,0.0016243159,0.8567749,0.0009677785,0.00012437324,0.0000047868157,0.00014895949,0.000540085,0.12806696,0.00076525315,0.00041863738,0.00012802864],"about_ca_topic_score_codex":0.005590655,"about_ca_topic_score_gemma":0.001021484,"teacher_disagreement_score":0.5997663,"about_ca_system_score_codex":0.0003565705,"about_ca_system_score_gemma":0.00054136897,"threshold_uncertainty_score":0.8451435},"labels":[],"label_agreement":null},{"id":"W2171832339","doi":"10.3410/b1-68","title":"The roles, mechanisms, and controversies of autophagy in mammalian biology","year":2009,"lang":"en","type":"article","venue":"F1000 Biology Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Autophagy; Biology; Cell biology; Mechanism (biology); Programmed cell death; Catabolism; Disease; Starvation; Homeostasis; Genetics; Metabolism; Apoptosis; Biochemistry; Medicine","score_opus":0.006308131692914431,"score_gpt":0.27160695438378346,"score_spread":0.265298822690869,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171832339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868461,0.008140126,0.00009090331,0.0022927248,0.00021464325,0.00030397938,0.000006857005,0.00003669589,0.0020679918],"genre_scores_gemma":[0.99771816,0.00050426193,0.00013328716,0.0011870913,0.000048496604,0.000008746271,0.000026700422,0.0000059429394,0.00036732588],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99903125,0.00007250436,0.00037704175,0.00023697688,0.000045921057,0.00023631226],"domain_scores_gemma":[0.99928445,0.00012291883,0.00018626358,0.0002997237,0.00003939407,0.00006723867],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032151278,0.00011692061,0.00033836384,0.000072936564,0.000055701123,0.000003607929,0.000053189397,0.00017369763,0.000047467543],"category_scores_gemma":[0.00013703923,0.00007445568,0.00005929057,0.00007896218,0.00021868924,0.00002068284,0.000021987822,0.00011190148,0.0000018405465],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017220201,0.0005582024,0.21278352,0.000044493114,0.0004220546,0.0027644923,0.0006593929,0.000002580297,0.42466995,0.24424782,0.0020659112,0.11005958],"study_design_scores_gemma":[0.0030203392,0.0025281904,0.55107415,0.000063877844,0.00012978075,0.0016790073,0.00027118414,0.00004813099,0.08388967,0.31240287,0.044603657,0.0002891458],"about_ca_topic_score_codex":0.000043963977,"about_ca_topic_score_gemma":0.000021805366,"teacher_disagreement_score":0.34078026,"about_ca_system_score_codex":0.000017984008,"about_ca_system_score_gemma":0.00007696269,"threshold_uncertainty_score":0.30362144},"labels":[],"label_agreement":null},{"id":"W2171908816","doi":"10.1128/mbio.00865-14","title":"Autophagy Facilitates <i>Salmonella</i> Replication in HeLa Cells","year":2014,"lang":"en","type":"article","venue":"mBio","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Salmonella; Cytosol; Cell biology; HeLa; Biology; Intracellular; Autophagosome; Intracellular parasite; Phagosome; Lysosome; Cell; Microbiology; Biochemistry; Bacteria; Genetics; Apoptosis; Enzyme","score_opus":0.010227157396050866,"score_gpt":0.26196805356936326,"score_spread":0.2517408961733124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171908816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98870105,0.00054417225,0.00022713892,0.0005563174,0.00010201622,0.0002169891,0.0000051601955,0.000095679105,0.009551458],"genre_scores_gemma":[0.99459016,0.000069373506,0.0002290038,0.0013227059,0.00008471624,0.00002571445,0.000029872032,0.0000135980645,0.0036348382],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992212,0.00003767804,0.00018104812,0.0002720618,0.000117807336,0.00017017733],"domain_scores_gemma":[0.99926984,0.000046864607,0.000036901656,0.0005322307,0.000026240947,0.00008792692],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020477195,0.00009390558,0.00016704595,0.00006012157,0.000026132635,0.0000082284805,0.00006853382,0.000070201146,0.00018210392],"category_scores_gemma":[0.000045515546,0.000083563296,0.000056160345,0.0001263331,0.000037297443,0.000037975853,0.000014488053,0.000093291965,0.00048012417],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039219242,0.0008759288,0.020943437,0.00020371829,0.00007309409,0.00007066642,0.0014308369,0.000043506494,0.8854646,0.0026156483,0.01019391,0.07769246],"study_design_scores_gemma":[0.001998973,0.00026159894,0.098884024,0.000061165396,0.000027684808,0.000011693739,0.00006184787,0.0013063414,0.81339306,0.0029893883,0.0808183,0.0001859189],"about_ca_topic_score_codex":0.00005186176,"about_ca_topic_score_gemma":0.0000034414857,"teacher_disagreement_score":0.07794059,"about_ca_system_score_codex":0.00003293049,"about_ca_system_score_gemma":0.000024444267,"threshold_uncertainty_score":0.61711854},"labels":[],"label_agreement":null},{"id":"W2196305814","doi":"10.1016/j.canlet.2015.11.035","title":"The synthetic β-nitrostyrene derivative CYT-Rx20 induces breast cancer cell death and autophagy via ROS-mediated MEK/ERK pathway","year":2015,"lang":"en","type":"article","venue":"Cancer Letters","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Kaohsiung Medical University Chung-Ho Memorial Hospital; National Health Research Institutes; Kaohsiung Medical University; Ministry of Health and Welfare","keywords":"ATG5; Apoptosis; Autophagy; Programmed cell death; Viability assay; Cytotoxicity; Cancer cell; Cancer research; Poly ADP ribose polymerase; Chemistry; Reactive oxygen species; Caspase; Cell growth; Molecular biology; Biology; Cancer; Biochemistry; Polymerase; In vitro; Enzyme","score_opus":0.018335305677315585,"score_gpt":0.2652540217005007,"score_spread":0.24691871602318513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2196305814","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9712597,0.016998276,0.00011155839,0.009922528,0.00057869434,0.00044837483,0.00017486457,0.00010922869,0.0003967374],"genre_scores_gemma":[0.9847948,0.0015579729,0.00005205685,0.012399424,0.0005526055,0.00029476392,0.000026998201,0.00005947982,0.00026188605],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983389,0.000098655466,0.00027225065,0.00041875674,0.0003774212,0.0004940477],"domain_scores_gemma":[0.99876475,0.00013215315,0.00016147587,0.00037717042,0.00013956678,0.0004248951],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017192002,0.00031499978,0.00036377512,0.000048984315,0.0002129369,0.00005623146,0.00018804983,0.00010882155,0.00017627962],"category_scores_gemma":[0.00002716957,0.00021306453,0.000085532265,0.0001899213,0.0002901567,0.0001566626,0.0000594454,0.00026209245,0.000027869448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019117428,0.000337073,0.027016211,0.0001916239,0.0010787228,0.000413114,0.0058906954,0.00010130893,0.8931616,0.00015386153,0.015351426,0.054392617],"study_design_scores_gemma":[0.012936353,0.00053936837,0.34912732,0.0007056841,0.00089970714,0.00022730464,0.0013495819,0.0012813882,0.5876353,0.0005543638,0.043174405,0.0015692445],"about_ca_topic_score_codex":0.0010815086,"about_ca_topic_score_gemma":0.00008645862,"teacher_disagreement_score":0.3221111,"about_ca_system_score_codex":0.0003960901,"about_ca_system_score_gemma":0.0004154511,"threshold_uncertainty_score":0.86885196},"labels":[],"label_agreement":null},{"id":"W2201007235","doi":"10.1038/cddiscovery.2015.8","title":"Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia","year":2015,"lang":"en","type":"article","venue":"Cell Death Discovery","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":163,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; National Institute for Health and Care Research; National Institutes of Health; Wellcome Trust; Lady Tata Memorial Trust; Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Haematopoiesis; Myeloid leukemia; Biology; ATG5; Progenitor cell; Myeloid; Cell biology; Cancer research; Stem cell; Population; Leukemia; Apoptosis; Immunology; Genetics; Medicine","score_opus":0.020790482850759524,"score_gpt":0.26834475692962284,"score_spread":0.24755427407886332,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2201007235","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98836124,0.005416359,0.00017528539,0.00014560416,0.00023657906,0.00048560466,0.000011175913,0.000056745164,0.00511138],"genre_scores_gemma":[0.99167114,0.00070240384,0.00024119583,0.001098034,0.00022062752,0.000057243993,0.000055458935,0.000030134717,0.0059237494],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99887,0.00004425643,0.00024777834,0.00031474204,0.00024844793,0.00027475762],"domain_scores_gemma":[0.99934083,0.000027942857,0.00006239943,0.00027436324,0.000045239278,0.0002492033],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014764236,0.00019384656,0.0003322617,0.00012649658,0.00003950406,0.000072528004,0.00007092103,0.00011555353,0.000020161757],"category_scores_gemma":[0.00003376482,0.00016224974,0.00006519597,0.00015588218,0.000046178127,0.00047951887,0.00003466811,0.00017273202,0.00005015134],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.022180706,0.0063623805,0.34787518,0.002307994,0.002429414,0.011893243,0.02237098,0.0014920514,0.4637636,0.051360924,0.022686895,0.045276638],"study_design_scores_gemma":[0.018167706,0.00074465276,0.64934117,0.00022789538,0.00086877646,0.00023813709,0.00037939244,0.0052674892,0.30997017,0.006473418,0.0075204116,0.00080080563],"about_ca_topic_score_codex":0.000032947162,"about_ca_topic_score_gemma":0.000005331348,"teacher_disagreement_score":0.30146596,"about_ca_system_score_codex":0.00016757214,"about_ca_system_score_gemma":0.0005495323,"threshold_uncertainty_score":0.6616352},"labels":[],"label_agreement":null},{"id":"W2201375678","doi":"10.1152/japplphysiol.00550.2015","title":"The regulation of autophagy during exercise in skeletal muscle","year":2015,"lang":"en","type":"review","venue":"Journal of Applied Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":133,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Autophagy; Cell biology; Transcription factor; Biology; Skeletal muscle; Mitochondrion; Mechanism (biology); Cellular stress response; Cellular adaptation; Mitophagy; Endocrinology; Fight-or-flight response; Biochemistry; Gene; Apoptosis","score_opus":0.023534198824156805,"score_gpt":0.3204116623082724,"score_spread":0.2968774634841156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2201375678","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.030521154,0.9684595,8.2776376e-7,0.000009561549,0.00020554576,0.00040362496,0.0000032957619,0.000005330225,0.00039116322],"genre_scores_gemma":[0.022950405,0.97647834,0.000049236267,0.000009099849,0.00038162232,0.000018148117,0.000012674434,0.000029353261,0.00007114539],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984021,0.00006934005,0.0009698247,0.00013829449,0.00023000811,0.00019042863],"domain_scores_gemma":[0.99816537,0.0001075129,0.0012210017,0.00029773553,0.000115870724,0.00009248837],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036109178,0.00020570848,0.0017089315,0.00019042515,0.000034326575,0.0000039207807,0.00021067138,0.00023434736,0.000044075994],"category_scores_gemma":[0.00001734151,0.00011893841,0.0004243531,0.0002070794,0.00011769079,0.000029672075,0.000041474566,0.00047082172,0.000011745639],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044926902,0.00019964078,2.5887417e-7,0.0047048116,0.00026895702,0.000025747793,0.00012862976,0.000020127687,0.0037125798,0.00045617906,0.00022719917,0.9898066],"study_design_scores_gemma":[0.0036584486,0.0002767129,0.015575464,0.011123319,0.001574348,0.00017018509,0.000100605095,0.000014699487,0.0006364388,0.0076204734,0.9589385,0.0003108277],"about_ca_topic_score_codex":0.0000011111679,"about_ca_topic_score_gemma":1.9138164e-7,"teacher_disagreement_score":0.98949575,"about_ca_system_score_codex":0.00010918709,"about_ca_system_score_gemma":0.0004530888,"threshold_uncertainty_score":0.48501676},"labels":[],"label_agreement":null},{"id":"W2202745454","doi":"10.1083/jcb.201501059","title":"RUN and FYVE domain–containing protein 4 enhances autophagy and lysosome tethering in response to Interleukin-4","year":2015,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Agence Nationale de la Recherche","keywords":"Tethering; Autophagy; Lysosome; Cell biology; Interleukin 1β; Chemistry; Interleukin; Biology; Immunology; Biochemistry; Cytokine","score_opus":0.017235371496463574,"score_gpt":0.29264111309846724,"score_spread":0.27540574160200365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2202745454","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945457,0.0037148288,0.00020085221,0.00097506016,0.00007697551,0.00018920893,7.787408e-7,0.000005939688,0.0002906739],"genre_scores_gemma":[0.99838394,0.00012824938,0.00072928274,0.00050258334,0.000106213454,0.0000036445178,2.1827114e-7,0.000009058197,0.0001367922],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990448,0.00034311117,0.00028423526,0.00008683381,0.000075216696,0.00016583041],"domain_scores_gemma":[0.99934244,0.00018558287,0.0001434778,0.000106539504,0.000056996156,0.00016498307],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015565429,0.000097921984,0.00028390865,0.00014092984,0.000028098159,0.000007911987,0.0000968057,0.00006467915,0.000016703741],"category_scores_gemma":[0.0001356916,0.000057457924,0.000027272357,0.00008000255,0.00010908937,0.000047242953,0.00005124682,0.0002065237,0.0000036359322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01027719,0.000036794147,0.0007014989,0.000011427367,0.00003510842,0.00008439936,0.006152678,0.0000032080172,0.97790474,0.000052598338,0.0000070509727,0.004733319],"study_design_scores_gemma":[0.008606545,0.011366808,0.03221627,0.00044511104,0.000073883006,0.0007874803,0.007908697,0.000045189834,0.9190028,0.012161157,0.0071373726,0.00024872617],"about_ca_topic_score_codex":0.000015700376,"about_ca_topic_score_gemma":0.000006072916,"teacher_disagreement_score":0.05890197,"about_ca_system_score_codex":0.0000470011,"about_ca_system_score_gemma":0.00011768533,"threshold_uncertainty_score":0.2343066},"labels":[],"label_agreement":null},{"id":"W2230576001","doi":"10.1007/s11515-015-1374-y","title":"Beclin 1-Vps34 complex architecture: Understanding the nuts and bolts of therapeutic targets","year":2015,"lang":"en","type":"article","venue":"Frontiers in Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences","keywords":"Autophagy; Cell biology; Intracellular; Mechanism (biology); Biology; Computational biology; Neuroscience; Biochemistry; Physics; Apoptosis","score_opus":0.07345596244074264,"score_gpt":0.3273377847262243,"score_spread":0.2538818222854817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2230576001","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8035577,0.052237064,0.13145824,0.006142714,0.0016245855,0.0010368625,0.000047295667,0.00007166204,0.0038238976],"genre_scores_gemma":[0.9967509,0.00024157325,0.0017151821,0.0011310559,0.000073183095,0.0000074407412,0.000029615345,0.000009973561,0.00004110608],"study_design_codex":"observational","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9992771,0.000121895384,0.00017823897,0.00016095639,0.00006957033,0.00019223953],"domain_scores_gemma":[0.9995958,0.0000594342,0.000064565975,0.00018376189,0.000019218027,0.00007719058],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002394324,0.00010245618,0.0002866925,0.00009559956,0.00003301045,0.0000031473678,0.00009305655,0.00009589927,0.000022771777],"category_scores_gemma":[0.000033552402,0.00006366723,0.000041649102,0.0001112851,0.00039358495,0.00001377444,0.0000291214,0.00014319771,0.0000010197086],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0045463657,0.0005406912,0.8388388,0.00015704446,0.0012245314,0.00008742236,0.01317009,0.00007228785,0.012001218,0.03254435,0.03130213,0.06551502],"study_design_scores_gemma":[0.010649418,0.0016536983,0.22272816,0.00009631002,0.00020358225,0.000094737494,0.0064501264,0.002641933,0.002522996,0.7142067,0.038344562,0.00040776868],"about_ca_topic_score_codex":0.000018179664,"about_ca_topic_score_gemma":0.000008223688,"teacher_disagreement_score":0.6816624,"about_ca_system_score_codex":0.000063123036,"about_ca_system_score_gemma":0.00005909038,"threshold_uncertainty_score":0.25962743},"labels":[],"label_agreement":null},{"id":"W2232078999","doi":"10.1016/j.cub.2015.11.054","title":"The Atg17-Atg31-Atg29 Complex Coordinates with Atg11 to Recruit the Vam7 SNARE and Mediate Autophagosome-Vacuole Fusion","year":2016,"lang":"en","type":"review","venue":"Current Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Biological and Environmental Research; National Institutes of Health; National Cancer Institute; Canadian Institutes of Health Research; National Institute of General Medical Sciences; University of British Columbia","keywords":"Autophagy; Vacuole; Biology; Cell biology; Autophagosome; Cytoplasm; Lipid bilayer fusion; BAG3; Autophagy-related protein 13; Biochemistry; Signal transduction","score_opus":0.1018576761710433,"score_gpt":0.42064443567137877,"score_spread":0.31878675950033547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2232078999","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000796428,0.9934068,0.0000399336,0.00175552,0.001023085,0.0023322909,0.00024289818,0.00009911091,0.00030397586],"genre_scores_gemma":[0.0007066768,0.9962652,0.000018208737,0.00034360256,0.00084508024,0.00055128627,0.00045958348,0.00006987511,0.0007405282],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99737704,0.0004536665,0.0005994376,0.00071757665,0.00020593333,0.00064631994],"domain_scores_gemma":[0.9973704,0.00084967306,0.00038508917,0.0009252666,0.00014208548,0.00032749283],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042338492,0.0006420434,0.0015605608,0.00013749932,0.00046982054,0.000041884832,0.0005773121,0.00031177307,0.00031310422],"category_scores_gemma":[0.00012579687,0.0002335098,0.00032245496,0.00032650816,0.00063618785,0.0000310914,0.0003325039,0.0005337645,0.00030518885],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011509007,0.00006405434,0.00012607207,0.0012995399,0.000314546,0.000014200835,0.00007437054,1.2938649e-8,0.000012814856,0.0012235099,0.0062683034,0.99048746],"study_design_scores_gemma":[0.0007911743,0.00056545105,0.00061388797,0.0058334824,0.00061508146,0.000105060724,0.000022694738,0.0000022961694,0.000007662162,0.00048936607,0.9906248,0.00032907914],"about_ca_topic_score_codex":0.000007742032,"about_ca_topic_score_gemma":0.000010573663,"teacher_disagreement_score":0.9901584,"about_ca_system_score_codex":0.00009395302,"about_ca_system_score_gemma":0.00031584306,"threshold_uncertainty_score":0.95222527},"labels":[],"label_agreement":null},{"id":"W2234636301","doi":"10.1007/s13277-015-4516-6","title":"The role of lysosome in cell death regulation","year":2015,"lang":"en","type":"review","venue":"Tumor Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Natural Science Foundation of China","keywords":"Lysosome; Autophagy; Cell biology; Autophagosome; Programmed cell death; Organelle; Cytosol; Biology; Chemistry; Apoptosis; Biochemistry; Enzyme","score_opus":0.03583761542366389,"score_gpt":0.3504466951420859,"score_spread":0.314609079718422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2234636301","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013576077,0.99372494,7.555796e-7,0.000010611053,0.000089041234,0.00042745407,0.000017255648,0.00001237989,0.004359959],"genre_scores_gemma":[0.0039095064,0.9952865,0.000020693684,0.00002759182,0.0001406202,0.000045599965,0.00015613603,0.000017643992,0.0003956667],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991109,0.00015776935,0.0003610509,0.00015834198,0.000058070593,0.00015386818],"domain_scores_gemma":[0.9992572,0.00009975437,0.00023207841,0.0003223066,0.000038959883,0.000049675342],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025093206,0.00014247387,0.0008485577,0.00008658204,0.00001624843,0.0000016643356,0.00012545014,0.00013872918,0.000048243815],"category_scores_gemma":[0.000028712258,0.00007733255,0.00015639579,0.00011912886,0.00007242883,0.0000073740443,0.00002862145,0.0001506614,0.000056908608],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000581465,0.000093402945,0.00031671955,0.0013736755,0.00006869474,0.000017925815,0.00003106715,9.1229836e-8,0.000059596292,0.0039668498,0.00010546177,0.99390835],"study_design_scores_gemma":[0.00029139736,0.00014339475,0.0002389507,0.00067509786,0.00017560447,0.000028906139,0.00001079469,0.0000047250014,0.00006848212,0.004888495,0.9934029,0.0000712542],"about_ca_topic_score_codex":0.00001943552,"about_ca_topic_score_gemma":0.000001896485,"teacher_disagreement_score":0.9938371,"about_ca_system_score_codex":0.000055457527,"about_ca_system_score_gemma":0.00030416943,"threshold_uncertainty_score":0.315353},"labels":[],"label_agreement":null},{"id":"W2240173075","doi":"10.1038/cdd.2015.160","title":"NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy","year":2016,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":241,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute for Occupational Safety and Health; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; Barth Syndrome Foundation; National Institutes of Health; Groupement des Entreprises Françaises dans la lutte contre le Cancer; Fondation pour la Recherche Médicale; National Institute of Environmental Health Sciences; U.S. Department of Veterans Affairs","keywords":"Mitophagy; Cardiolipin; Cell biology; Mitochondrion; Chemistry; Mitochondrial fission; Biology; Biochemistry; Autophagy; Phospholipid; Apoptosis; Membrane","score_opus":0.0066230220929470816,"score_gpt":0.22203950208271833,"score_spread":0.21541647998977126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2240173075","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9735407,0.0025566462,0.023100972,0.00004644193,0.00013654426,0.00028176396,0.000056504454,0.00003263606,0.0002477565],"genre_scores_gemma":[0.99748796,0.0015567173,0.00016476061,0.000035193065,0.00007002559,0.000014555773,0.00028931999,0.000015631844,0.00036581015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990699,0.0000543281,0.00033166038,0.00018654599,0.00022646338,0.0001310775],"domain_scores_gemma":[0.99926776,0.000080374215,0.0002436324,0.00017024516,0.00014243304,0.000095531934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005296736,0.00012783926,0.00028590552,0.00012033334,0.00003177549,0.0000073031506,0.00004400538,0.00011540403,0.00008979515],"category_scores_gemma":[0.000063739826,0.000089870555,0.00008707171,0.0000918006,0.000039285467,0.000110710964,0.000013558436,0.00003355582,0.000003121529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036459405,0.00018483122,0.06634797,0.00017516455,0.00006469322,0.0000011687595,0.00010734484,2.851218e-7,0.9287038,0.00019827073,0.0002466675,0.0036052477],"study_design_scores_gemma":[0.0037578836,0.00020264732,0.27704272,0.00012962596,0.00015794474,0.0000019446463,0.000027009883,0.00033416707,0.7177566,0.0003768231,0.00012055115,0.00009203162],"about_ca_topic_score_codex":0.000035336627,"about_ca_topic_score_gemma":0.0000014634192,"teacher_disagreement_score":0.21094711,"about_ca_system_score_codex":0.000023391807,"about_ca_system_score_gemma":0.000035036457,"threshold_uncertainty_score":0.3664815},"labels":[],"label_agreement":null},{"id":"W2249194240","doi":"10.1242/jcs.177071","title":"The Ccl1–Kin28 kinase complex regulates autophagy under nitrogen starvation","year":2015,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Toronto; National Natural Science Foundation of China","keywords":"Autophagy; Biology; Regulator; Cell biology; Kinase; BAG3; Transcription factor; ULK1; Protein kinase A; Biochemistry; Apoptosis; Gene","score_opus":0.04610200886433859,"score_gpt":0.3141839052486802,"score_spread":0.2680818963843416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2249194240","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924546,0.0011633345,0.0003971252,0.0030868645,0.00030365275,0.000094083975,7.648534e-7,0.0000110976425,0.0024885118],"genre_scores_gemma":[0.99704087,0.000073095434,0.001018291,0.0010863659,0.00021118422,7.178808e-7,6.6968244e-7,0.000006613896,0.0005621746],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99850947,0.000035191515,0.00029675185,0.000101956306,0.0008350979,0.00022153613],"domain_scores_gemma":[0.99855787,0.00006625451,0.0002824476,0.00021023798,0.0005532218,0.00032999367],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012157612,0.00008018971,0.00014506975,0.0000983168,0.00021872595,0.0000751321,0.00030427435,0.000026947451,0.00006532315],"category_scores_gemma":[0.00011269465,0.00004566579,0.00007702559,0.00039145825,0.00041708644,0.00028156128,0.000033126147,0.00013342226,0.000026294174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010587121,0.00068794977,0.0038934564,0.000028763434,0.00009366684,0.00028481233,0.0021344998,0.0007506395,0.9496764,0.005062518,0.02582492,0.010503643],"study_design_scores_gemma":[0.004478501,0.0014144551,0.07555572,0.000084616724,0.00014147893,0.0004268902,0.00162873,0.004509685,0.7895675,0.04904797,0.07291194,0.00023257408],"about_ca_topic_score_codex":0.00000585873,"about_ca_topic_score_gemma":8.604361e-7,"teacher_disagreement_score":0.16010898,"about_ca_system_score_codex":0.00014080048,"about_ca_system_score_gemma":0.00082716526,"threshold_uncertainty_score":0.18621969},"labels":[],"label_agreement":null},{"id":"W2250268908","doi":"10.1016/j.bbamcr.2016.01.016","title":"Activation of autophagy by globular adiponectin is required for muscle differentiation","year":2016,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Ministero dell'Università e della Ricerca; Ente Cassa di Risparmio di Firenze","keywords":"Autophagy; Skeletal muscle; Cell biology; Myocyte; Myosin; AMPK; Chemistry; Endocrinology; Biology; Internal medicine; Apoptosis; Biochemistry; Medicine","score_opus":0.034388971010425054,"score_gpt":0.3432967840721317,"score_spread":0.30890781306170667,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2250268908","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99044406,0.00022646839,0.0032578125,0.0038644234,0.000060429968,0.0012775412,0.0001602431,0.00006779179,0.0006412296],"genre_scores_gemma":[0.99738485,0.00024047682,0.00037070803,0.00039620654,0.000105686515,0.00016106252,0.00021930813,0.00008309338,0.0010386372],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99706227,0.00028422108,0.0004180567,0.0006582923,0.0009772152,0.0005999511],"domain_scores_gemma":[0.99792343,0.00030227657,0.00020680806,0.0008165712,0.0005003477,0.000250569],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004770624,0.0002714795,0.0004074957,0.00028055478,0.00014211168,0.000037739996,0.00031882752,0.00023206974,0.00014935917],"category_scores_gemma":[0.00019287146,0.00020780113,0.00032768847,0.0005106151,0.00023047467,0.00016028206,0.00011063684,0.00021375454,0.00003990702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008176014,0.00083483336,0.0000039080655,0.00018103074,0.00018808762,0.0000049665005,0.00019553592,1.4638724e-7,0.9894418,0.00032768812,0.004397846,0.003606524],"study_design_scores_gemma":[0.002955475,0.00089058705,0.0023677698,0.00016569655,0.00009063726,7.870431e-7,0.00003581236,0.00018074979,0.99027073,0.001278885,0.0015435907,0.00021926055],"about_ca_topic_score_codex":0.000038928367,"about_ca_topic_score_gemma":2.7263695e-7,"teacher_disagreement_score":0.0069407606,"about_ca_system_score_codex":0.00015422533,"about_ca_system_score_gemma":0.00027634422,"threshold_uncertainty_score":0.8473884},"labels":[],"label_agreement":null},{"id":"W2252515498","doi":"10.1074/jbc.m115.678557","title":"The Retinoblastoma Tumor Suppressor Protein (pRb)/E2 Promoter Binding Factor 1 (E2F1) Pathway as a Novel Mediator of TGFβ-induced Autophagy","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; E2F1; Cell biology; Carcinogenesis; Biology; Retinoblastoma; Retinoblastoma protein; Cancer research; Programmed cell death; Transcription factor; Signal transduction; Transforming growth factor; Mediator; Cell cycle; Cell; Cancer; Gene; Apoptosis; Genetics","score_opus":0.04582726998783532,"score_gpt":0.2892708585404114,"score_spread":0.24344358855257608,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2252515498","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99781597,0.0004951705,0.000012826534,0.00059940043,0.0001520191,0.0003183807,0.000040275227,0.000029006866,0.0005369367],"genre_scores_gemma":[0.99858683,0.00001607012,0.00027632617,0.000113011236,0.000635563,0.000018053894,0.000006842674,0.000020484295,0.00032680648],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99797285,0.00006827499,0.00080097845,0.00022363143,0.0005792647,0.00035501277],"domain_scores_gemma":[0.9977502,0.00016643501,0.0008297776,0.0003029244,0.00043489502,0.00051573315],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005647416,0.00024926677,0.00057900546,0.000035767873,0.000071970324,0.00002760085,0.000377371,0.00026419142,0.00031362768],"category_scores_gemma":[0.0018005474,0.0001272963,0.0003247949,0.00014398381,0.00020017201,0.00007316843,0.000085621235,0.00059467426,0.000015130386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00149093,0.0005283761,0.0005063791,0.0000700993,0.0001515025,0.00026942458,0.00013613183,2.0250668e-7,0.99621606,0.000013706871,0.00014708246,0.000470124],"study_design_scores_gemma":[0.0026007746,0.0017000647,0.0016335917,0.00023012857,0.00003866059,0.00058194075,0.000281131,0.000016483322,0.9908607,0.00022065945,0.001688609,0.00014725515],"about_ca_topic_score_codex":0.0000019472996,"about_ca_topic_score_gemma":8.2107896e-8,"teacher_disagreement_score":0.00535534,"about_ca_system_score_codex":0.00010561914,"about_ca_system_score_gemma":0.0005333934,"threshold_uncertainty_score":0.51909924},"labels":[],"label_agreement":null},{"id":"W2256408507","doi":"10.1007/s10741-016-9532-0","title":"Role of cell death in the progression of heart failure","year":2016,"lang":"en","type":"review","venue":"Heart Failure Reviews","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":133,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Autophagy; Programmed cell death; Mitophagy; Necroptosis; Cell biology; Mitochondrion; Apoptosis; Medicine; Necrosis; Mitochondrial permeability transition pore; Biology; Cancer research; Pathology; Biochemistry","score_opus":0.03665448021452719,"score_gpt":0.36550701174768185,"score_spread":0.32885253153315464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2256408507","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000051223717,0.99435955,0.0000027729368,0.0006840284,0.000046204746,0.004309988,0.000036563106,0.000018597566,0.0004910505],"genre_scores_gemma":[0.00009995239,0.99589646,0.00280592,0.00021697907,0.000245191,0.00046450752,0.000062248306,0.000062503095,0.00014625101],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961744,0.0009342832,0.0015821463,0.00044997095,0.00048690292,0.00037230336],"domain_scores_gemma":[0.99749744,0.00022262518,0.0007644243,0.001293789,0.0000831949,0.00013852326],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012321139,0.0005304661,0.0040154094,0.00021812809,0.00003934614,0.000009313537,0.0003548876,0.0004122356,0.00047127716],"category_scores_gemma":[0.000094820985,0.00024065074,0.0015113831,0.0005189365,0.00010154829,0.000064241154,0.00006467349,0.0005331158,0.00030955227],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029889608,0.0006952636,0.00034246547,0.09116889,0.000101572165,0.0000147567025,0.00015267926,1.0166658e-8,0.0004426331,0.00026106695,0.048537448,0.8582533],"study_design_scores_gemma":[0.00037516776,0.00021589147,0.00004633742,0.09346935,0.00051216094,0.00008819471,0.000017956272,1.6232264e-7,0.00017102233,0.00003697317,0.9048787,0.00018809008],"about_ca_topic_score_codex":0.000007575032,"about_ca_topic_score_gemma":0.0000051714965,"teacher_disagreement_score":0.85806525,"about_ca_system_score_codex":0.00003813852,"about_ca_system_score_gemma":0.00042444424,"threshold_uncertainty_score":0.98134524},"labels":[],"label_agreement":null},{"id":"W2257031513","doi":"10.1111/cea.12633","title":"Autophagy and Asthma","year":2015,"lang":"en","type":"editorial","venue":"Clinical & Experimental Allergy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Autophagy; Asthma; Medicine; Immunology; Intensive care medicine; Biology; Genetics","score_opus":0.03759759564138671,"score_gpt":0.4165230672720979,"score_spread":0.3789254716307112,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2257031513","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03516412,0.039692286,0.0000048323554,0.00018136973,0.9136001,0.000517171,0.00009298872,0.00025171475,0.0104954345],"genre_scores_gemma":[0.013978147,0.002922607,0.00031747922,0.0010884658,0.96726304,0.00009304738,0.00088357815,0.00016045767,0.013293177],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99669087,0.00015297403,0.0009290281,0.0009066779,0.00090485247,0.00041560284],"domain_scores_gemma":[0.9974718,0.00048252768,0.00025587474,0.00065482035,0.00018596127,0.00094901933],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00044916628,0.0005024228,0.0012203257,0.000075365766,0.000078270175,0.000045776713,0.00023839036,0.0014391708,0.0010331128],"category_scores_gemma":[0.0005204274,0.0004292679,0.0004243905,0.000078363024,0.00046585983,0.00007670203,0.00028102117,0.0010490305,0.00034426304],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010644809,0.001131312,0.000011789596,0.00003049346,0.000542142,0.00037233118,0.00010356284,8.293853e-8,0.00018495963,0.0001087234,0.9931405,0.0033096268],"study_design_scores_gemma":[0.005495116,0.0024446794,0.00022898693,0.000147439,0.00006033546,0.000017209488,0.0001109449,0.00002220815,0.0012742461,0.0002078622,0.9895953,0.00039565272],"about_ca_topic_score_codex":0.000039200306,"about_ca_topic_score_gemma":0.0000025318143,"teacher_disagreement_score":0.05366296,"about_ca_system_score_codex":0.00014189727,"about_ca_system_score_gemma":0.0007214989,"threshold_uncertainty_score":0.9998801},"labels":[],"label_agreement":null},{"id":"W2274636564","doi":"10.7287/peerj.preprints.556v1","title":"Systematic review of the statistical scope used in studies based on skeletal muscle autophagy and exercise","year":2014,"lang":"en","type":"preprint","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Scope (computer science); Skeletal muscle; Autophagy; Credibility; Statistical analysis; Statistical hypothesis testing; Bioinformatics; Medicine; Physiology; Computer science; Biology; Statistics; Internal medicine; Mathematics; Biochemistry","score_opus":0.023696054730861213,"score_gpt":0.33435198953030265,"score_spread":0.3106559347994414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2274636564","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.25251782,0.72009045,0.0014548897,0.0026313302,0.00096229994,0.018802349,0.00018914019,0.00018363527,0.0031680516],"genre_scores_gemma":[0.96588033,0.029959472,0.00047555545,0.0028714363,0.000038587972,0.00039120705,0.00002811153,0.000034836845,0.0003204792],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.9979758,0.0003264488,0.00074793777,0.00034343527,0.00044467795,0.00016166693],"domain_scores_gemma":[0.998163,0.0004931506,0.0002736848,0.0008812222,0.00010184769,0.00008712015],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007471497,0.00026967912,0.0017244411,0.000083642015,0.000027028076,0.000008331072,0.0001633081,0.00011908394,0.00018018161],"category_scores_gemma":[0.0007963631,0.0001444654,0.00017930064,0.00009369576,0.0001746083,0.000011874617,0.00016938153,0.00032090233,0.000011854985],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003544778,0.00024419802,0.000083298975,0.99768263,0.00017481676,0.000030429817,0.00010149296,0.000014940521,0.000018952047,0.0006385449,0.00053357054,0.00044167423],"study_design_scores_gemma":[0.0014587225,0.0001769295,0.012977096,0.9792912,0.0015298991,0.0000028160716,0.000069235735,0.0031075913,0.0004488,0.0007093513,0.000014949665,0.0002134006],"about_ca_topic_score_codex":0.000021251533,"about_ca_topic_score_gemma":0.000004337813,"teacher_disagreement_score":0.71336246,"about_ca_system_score_codex":0.00006110074,"about_ca_system_score_gemma":0.0001921312,"threshold_uncertainty_score":0.5891128},"labels":[],"label_agreement":null},{"id":"W2282647145","doi":"10.1016/j.ijcard.2016.02.128","title":"The roles of autophagy in vascular smooth muscle cells","year":2016,"lang":"en","type":"review","venue":"International Journal of Cardiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Vascular smooth muscle; Cell biology; Medicine; Intracellular; Extracellular matrix; Restenosis; Programmed cell death; Biology; Smooth muscle; Internal medicine; Apoptosis; Biochemistry","score_opus":0.020126762390190654,"score_gpt":0.3420245192282159,"score_spread":0.32189775683802524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2282647145","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005078163,0.99632025,0.00019958094,0.00012994786,0.0016535147,0.00015316319,0.000027226044,0.000003576121,0.0010049123],"genre_scores_gemma":[0.003718742,0.99460375,0.000030521784,0.000056332578,0.0014707576,0.0000075682306,0.0000058440905,0.000022021357,0.00008447954],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99804115,0.0002885203,0.0009672247,0.00012486758,0.00042421604,0.00015400784],"domain_scores_gemma":[0.99803656,0.00047202816,0.00081883074,0.00022994011,0.00037588394,0.00006677233],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006739393,0.00017696036,0.0014208023,0.00029911747,0.000014831372,0.000008105106,0.0005546215,0.00020543294,0.00005197222],"category_scores_gemma":[0.00013326445,0.00008936235,0.0013086079,0.000067712586,0.00014782065,0.00003989377,0.00005796972,0.00033559115,0.000019028583],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000076196826,0.000032028183,0.000012580429,0.00021498956,0.0021190678,0.00058175647,0.000020616355,0.000007685298,0.00006548747,0.00040673985,0.0005521481,0.9959107],"study_design_scores_gemma":[0.0008586182,0.00011553469,0.00066403026,0.004172238,0.0003614102,0.00020154343,0.000010399508,8.510961e-7,0.000030298135,0.0005233771,0.9929891,0.000072568946],"about_ca_topic_score_codex":0.0000014549798,"about_ca_topic_score_gemma":8.4440984e-7,"teacher_disagreement_score":0.9958381,"about_ca_system_score_codex":0.00014546311,"about_ca_system_score_gemma":0.00053317874,"threshold_uncertainty_score":0.3644091},"labels":[],"label_agreement":null},{"id":"W2284905033","doi":"10.1016/s0076-6879(08)03620-3","title":"Chapter 20 Methods to Monitor Autophagy of Salmonella enterica serovar Typhimurium","year":2009,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Salmonella enterica; Autophagy; Salmonella; Microbiology; Innate immune system; Serotype; Intracellular; Biology; Cytosol; Intracellular parasite; Pathogen; Immune system; Bacteria; Cell biology; Immunology; Apoptosis; Enzyme; Biochemistry; Genetics","score_opus":0.047496676114469706,"score_gpt":0.45230103608215483,"score_spread":0.4048043599676851,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2284905033","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.57498956,0.0051681637,0.39401457,0.004105172,0.004806229,0.0027616047,0.000051237224,0.00041444376,0.013689054],"genre_scores_gemma":[0.12864849,0.00024629408,0.8613046,0.007897446,0.00040210225,0.00021365742,0.000022535389,0.00014144437,0.0011234512],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.98154336,0.011782105,0.0024886506,0.0019814635,0.00043896568,0.0017654264],"domain_scores_gemma":[0.9911388,0.005139684,0.00068602705,0.0021344642,0.00026816854,0.0006328207],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.010451754,0.0011119501,0.0034387119,0.002457843,0.00011912846,0.00001841229,0.0010722206,0.0015458828,0.0012657422],"category_scores_gemma":[0.0032348102,0.0010651539,0.00060491834,0.0017443838,0.000742566,0.00013289117,0.0003250847,0.0019088589,0.00009071896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035171325,0.0019770882,0.0020195877,0.0000979312,0.00027831137,0.0010708218,0.0014233057,0.00023468792,0.62263197,0.0096824225,0.00033220512,0.35673454],"study_design_scores_gemma":[0.007646971,0.009277225,0.34346884,0.00034585103,0.00033700667,0.0011348998,0.00034749717,0.00053937186,0.5505052,0.06699387,0.017905938,0.001497322],"about_ca_topic_score_codex":0.00014243565,"about_ca_topic_score_gemma":0.000029789722,"teacher_disagreement_score":0.46729,"about_ca_system_score_codex":0.00038421963,"about_ca_system_score_gemma":0.00018777119,"threshold_uncertainty_score":0.9997503},"labels":[],"label_agreement":null},{"id":"W2286538882","doi":"10.1371/journal.pone.0146770","title":"MiR-1303 Regulates Mycobacteria Induced Autophagy by Targeting Atg2B","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of British Columbia; Health and Medical Research Fund; University of Hong Kong","keywords":"Autophagy; Innate immune system; Biology; Cell biology; Immunity; Downregulation and upregulation; microRNA; Translation (biology); PI3K/AKT/mTOR pathway; Function (biology); Acquired immune system; Microbiology; Gene; Immune system; Immunology; Signal transduction; Genetics; Messenger RNA; Apoptosis","score_opus":0.03057724711159655,"score_gpt":0.24214483553823982,"score_spread":0.21156758842664328,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2286538882","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99560183,0.0008738951,0.000011927644,0.0015946402,0.000087194974,0.00031673795,0.000031937194,0.00024708718,0.0012347655],"genre_scores_gemma":[0.9929975,0.00015555997,0.00064792286,0.00076424313,0.00041313682,0.000040847393,0.00005032124,0.000052328192,0.00487813],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986409,0.00004756948,0.0002810852,0.0003220834,0.00034442035,0.0003639636],"domain_scores_gemma":[0.9990977,0.00007987361,0.000103304614,0.00038660434,0.00009639283,0.00023609323],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00012861613,0.00019301669,0.00037022954,0.00005952295,0.00007728627,0.000016974642,0.00011883833,0.00014396232,0.0024557007],"category_scores_gemma":[0.00014953632,0.0001322794,0.000085785876,0.00011419519,0.000054434626,0.00013009977,0.000039745366,0.000111356494,0.00050444977],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017848867,0.000963275,0.0021690992,0.00006230228,0.00039944323,0.000028380462,0.00009486423,5.3876668e-9,0.9902863,0.000078633326,0.0039249444,0.0018142769],"study_design_scores_gemma":[0.0019780702,0.0002581757,0.01704265,0.0004204409,0.00017666764,0.0000034392747,0.000015478248,0.000013998415,0.97792304,0.00041782222,0.0015600428,0.00019018038],"about_ca_topic_score_codex":0.0000112718435,"about_ca_topic_score_gemma":3.8960835e-7,"teacher_disagreement_score":0.01487355,"about_ca_system_score_codex":0.000070091526,"about_ca_system_score_gemma":0.0000642985,"threshold_uncertainty_score":0.9984562},"labels":[],"label_agreement":null},{"id":"W2292716261","doi":"10.1038/cddis.2015.406","title":"Knockout of Atg5 delays the maturation and reduces the survival of adult-generated neurons in the hippocampus","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; Ontario Ministry of Research and Innovation; Mitacs; Heart and Stroke Foundation of Canada","keywords":"ATG5; Neurogenesis; Autophagy; Biology; Cell biology; Neural stem cell; Progenitor cell; Dentate gyrus; Embryonic stem cell; Hippocampal formation; Programmed cell death; Stem cell; Cellular differentiation; Apoptosis; Neuroscience; Gene; Genetics","score_opus":0.013846260004343119,"score_gpt":0.24803857195220816,"score_spread":0.23419231194786505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2292716261","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99292916,0.0038456856,0.000010434204,0.0024058083,0.00005480076,0.00028948058,0.00003714389,0.0000064208484,0.00042107108],"genre_scores_gemma":[0.9981079,0.0010956407,0.0000046768755,0.00058802235,0.000060882252,0.000017043787,0.000010087707,0.000006759034,0.0001090048],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9993505,0.00013315346,0.0001550417,0.00012223786,0.00013393241,0.00010516836],"domain_scores_gemma":[0.9993415,0.00018455647,0.000067269684,0.0002436734,0.000053055373,0.00010994116],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012321844,0.00008752443,0.00011468301,0.000023141078,0.00006936561,0.000010123288,0.00008424755,0.000026027992,0.000020486446],"category_scores_gemma":[0.00009923984,0.000031677817,0.000042501622,0.0000796575,0.00015792334,0.000038704344,0.000018374176,0.000051964347,0.0000013087015],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018368764,0.0027955868,0.3079807,0.0010163446,0.00036810545,0.00033588198,0.011438234,0.00003836149,0.47832304,0.018094743,0.0064922404,0.15474802],"study_design_scores_gemma":[0.003080612,0.00022687805,0.96673596,0.00012400032,0.00034894084,0.000009220582,0.0009024639,0.00040889977,0.020224644,0.007529487,0.0002840139,0.00012488423],"about_ca_topic_score_codex":0.000022073109,"about_ca_topic_score_gemma":0.0000042383995,"teacher_disagreement_score":0.65875524,"about_ca_system_score_codex":0.00000380184,"about_ca_system_score_gemma":0.00008733876,"threshold_uncertainty_score":0.12917839},"labels":[],"label_agreement":null},{"id":"W2295320282","doi":"10.1016/j.bbrc.2016.03.043","title":"Deciphering the role of Atg5 in nucleotide dependent interaction of Rab33B with the dimeric complex, Atg5-Atg16L1","year":2016,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"ATG5; ATG16L1; Autophagy; Cell biology; Effector; ATG12; Biology; Chemistry; Biochemistry","score_opus":0.06468788679396882,"score_gpt":0.3764801872669666,"score_spread":0.3117923004729978,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2295320282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99105036,0.00085234054,0.00002745988,0.0070600165,0.0000042476595,0.00026802102,0.0000074942072,0.0000075565786,0.0007225075],"genre_scores_gemma":[0.99880314,0.0008457554,0.00016387935,0.0000484435,0.000026476295,0.00004915273,0.000006536867,0.000008006973,0.000048623373],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999037,0.0001565774,0.00018221783,0.00012777913,0.0003277749,0.00016862189],"domain_scores_gemma":[0.9979211,0.0009692066,0.00005811454,0.00081752095,0.000158607,0.000075431584],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002859723,0.00007376039,0.00016081304,0.00004282677,0.00010956121,0.000008430779,0.00043549034,0.00003649791,0.000028909013],"category_scores_gemma":[0.00012110714,0.000030626532,0.000052774856,0.00033075328,0.0012279997,0.00004069887,0.0002690359,0.00027330813,0.0000056473477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033883486,0.00042838836,0.0022371467,0.00001539648,0.00004731494,5.34729e-7,0.00017762539,1.8837353e-7,0.98021615,0.002733068,0.00008510583,0.013720252],"study_design_scores_gemma":[0.0014278071,0.00047700974,0.14714375,0.000435394,0.000053445525,0.000007813519,0.0016710212,0.0008378437,0.8393341,0.0027785895,0.0057117064,0.00012157933],"about_ca_topic_score_codex":0.00019768687,"about_ca_topic_score_gemma":0.000023024686,"teacher_disagreement_score":0.1449066,"about_ca_system_score_codex":0.000034432887,"about_ca_system_score_gemma":0.000054595137,"threshold_uncertainty_score":0.4524616},"labels":[],"label_agreement":null},{"id":"W2296508383","doi":"10.1016/j.dib.2016.03.008","title":"Autophagic flux data in differentiated C2C12 myotubes following exposure to acetylcholine and caffeine","year":2016,"lang":"en","type":"article","venue":"Data in Brief","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Myogenesis; C2C12; Caffeine; Myocyte; Skeletal muscle; Autophagy; Cell biology; Contraction (grammar); Acetylcholine; Calcium; Chemistry; Acetylcholine receptor; Biology; Pharmacology; Endocrinology; Biochemistry; Receptor","score_opus":0.043329044667578455,"score_gpt":0.32735097303664035,"score_spread":0.28402192836906187,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2296508383","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935895,0.001891042,0.00018614747,0.0020365147,0.00017976423,0.00043501088,0.001492741,0.00006828889,0.00012096203],"genre_scores_gemma":[0.99264836,0.00026262738,0.00034616067,0.0012229463,0.00015604883,0.000016430473,0.004650359,0.000034763118,0.0006623109],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99814856,0.00006913827,0.00038202287,0.00076149724,0.0002681143,0.00037065317],"domain_scores_gemma":[0.99705625,0.000117170406,0.00004416405,0.0025488338,0.000017422079,0.0002161437],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041904103,0.00021477221,0.00042760218,0.00019329198,0.000036100373,0.000030764797,0.00072830176,0.000105689665,0.0003560738],"category_scores_gemma":[0.00039551916,0.00015209944,0.00002655811,0.00028947834,0.000047711666,0.000501323,0.00095401134,0.00014920942,0.000053699172],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015936616,0.0019897248,0.64694,0.00029971552,0.00060889195,0.0025017778,0.0011323541,0.000002197318,0.15761013,0.0002803211,0.031858496,0.15518272],"study_design_scores_gemma":[0.010249052,0.00022751544,0.9567505,0.000830755,0.00010026242,0.000030065083,0.00007312907,0.00043203234,0.0035326171,0.00011386073,0.027302256,0.00035791282],"about_ca_topic_score_codex":0.00028124952,"about_ca_topic_score_gemma":0.00030594447,"teacher_disagreement_score":0.30981055,"about_ca_system_score_codex":0.000043806616,"about_ca_system_score_gemma":0.00007171592,"threshold_uncertainty_score":0.6202435},"labels":[],"label_agreement":null},{"id":"W2309000138","doi":"10.1002/jnr.23733","title":"Autophagy inhibition in endogenous and nutrient‐deprived conditions reduces dorsal root ganglia neuron survival and neurite growth in vitro","year":2016,"lang":"en","type":"article","venue":"Journal of Neuroscience Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Neurite; Cell biology; Dorsal root ganglion; Biology; Neuron; Programmed cell death; Neuroscience; In vitro; Biochemistry; Apoptosis; Spinal cord","score_opus":0.07868033184949441,"score_gpt":0.36638553811322777,"score_spread":0.28770520626373336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2309000138","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99567044,0.0005986268,0.000014449607,0.0031674854,0.00017457225,0.00024554218,0.000011728332,0.0000076188744,0.000109512155],"genre_scores_gemma":[0.99789405,0.0018030233,0.000013712733,0.00013055999,0.00009053075,0.0000068180434,6.485173e-7,0.00001239902,0.000048270078],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99770385,0.00040963283,0.0003862088,0.00029331466,0.0007740971,0.0004328816],"domain_scores_gemma":[0.99890274,0.0003906564,0.00010999708,0.00012114103,0.00021442966,0.00026102018],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012400858,0.00011013346,0.00026449622,0.00088054466,0.0001260598,0.000058629998,0.00011135107,0.000055091066,0.000010394072],"category_scores_gemma":[0.00092159247,0.000076122575,0.0000437448,0.0007089814,0.0005914483,0.0004545354,0.00008381371,0.0004711148,0.000001754288],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006275719,0.00030073008,0.006411008,0.000018364997,0.0000021229516,0.0030079798,0.00017570799,6.156512e-7,0.98791295,0.00018436158,0.000019808056,0.0013387954],"study_design_scores_gemma":[0.003264186,0.0009538479,0.5610618,0.00017261111,0.0000065649606,0.0009927049,0.000106761756,0.00007791091,0.43048134,0.0027350585,0.00006968764,0.00007751872],"about_ca_topic_score_codex":0.00002282777,"about_ca_topic_score_gemma":0.0000037374507,"teacher_disagreement_score":0.5574316,"about_ca_system_score_codex":0.00007852615,"about_ca_system_score_gemma":0.00025441748,"threshold_uncertainty_score":0.31041884},"labels":[],"label_agreement":null},{"id":"W2310360756","doi":"10.1530/erc-15-0042","title":"Autophagy in endocrine tumors","year":2015,"lang":"en","type":"review","venue":"Endocrine Related Cancer","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Autophagy; Endocrine system; Biology; Context (archaeology); Cancer research; Cancer; Pancreas; Cell biology; Endocrinology; Hormone; Apoptosis; Biochemistry; Genetics","score_opus":0.059445931346016626,"score_gpt":0.42773020507760057,"score_spread":0.36828427373158396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2310360756","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001738297,0.9857892,5.9293683e-7,0.00014011857,0.0007940229,0.0015710426,0.00009262048,0.0002828478,0.011155728],"genre_scores_gemma":[0.00014318753,0.9770355,0.000034891284,0.00016984293,0.0005188041,0.000793613,0.00039369724,0.00022053889,0.020689892],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.996257,0.00018844896,0.0013009809,0.00082404143,0.0005562212,0.0008732749],"domain_scores_gemma":[0.99801326,0.00008280121,0.00042272848,0.00086252356,0.00012100704,0.0004976859],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018641858,0.0008296074,0.0033210577,0.00067039917,0.000042700965,0.000020823847,0.0003266562,0.00023261797,0.0036710093],"category_scores_gemma":[0.000080496764,0.00065490283,0.0007535249,0.0011985826,0.00010593518,0.00010227613,0.00012269072,0.0015454348,0.0007265416],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000066932116,0.00026718553,0.0000372005,0.0074771754,0.0009757163,0.008988553,0.00004877392,0.000007921839,0.0000011544143,0.0003998654,0.0065576853,0.97517186],"study_design_scores_gemma":[0.0027692653,0.00014112111,0.00003685834,0.016878542,0.0017014667,0.0017078057,0.000007833323,0.000018460294,0.000024545307,0.00021419919,0.97595227,0.0005476562],"about_ca_topic_score_codex":0.00035044755,"about_ca_topic_score_gemma":0.000018511824,"teacher_disagreement_score":0.97462416,"about_ca_system_score_codex":0.0010942974,"about_ca_system_score_gemma":0.0022177536,"threshold_uncertainty_score":0.9995902},"labels":[],"label_agreement":null},{"id":"W2313559625","doi":"10.1177/1535370214557223","title":"High-fat feeding does not induce an autophagic or apoptotic phenotype in female rat skeletal muscle","year":2014,"lang":"en","type":"article","venue":"Experimental Biology and Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Skeletal muscle; Internal medicine; Endocrinology; Soleus muscle; Muscle atrophy; Biology; Apoptosis; ATG12; Cell biology; Chemistry; ATG5; Biochemistry; Medicine","score_opus":0.02381143428266443,"score_gpt":0.33581779041355647,"score_spread":0.31200635613089206,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2313559625","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953641,0.0017693753,0.000020276084,0.0009028932,0.00090688624,0.00030051597,0.000003228139,0.0000752853,0.0006574143],"genre_scores_gemma":[0.99469304,0.00010254728,0.00023771264,0.0031225032,0.0010496249,0.000036152236,0.0000839395,0.00002236241,0.0006521155],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986924,0.000112376365,0.00030612905,0.000434623,0.00011715791,0.0003373383],"domain_scores_gemma":[0.99930567,0.000099775134,0.000072794384,0.00024269699,0.000020910002,0.0002581833],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00025859193,0.00023939449,0.00051339815,0.00014110518,0.00011143815,0.0000056700687,0.00009657349,0.00018853953,0.0013998542],"category_scores_gemma":[0.00008407171,0.00013752667,0.00003619155,0.000128283,0.0004377206,0.0001006148,0.000048664228,0.00022305538,0.000028833994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005374797,0.0003586253,0.0022904098,0.0000328457,0.000041437426,0.00005608113,0.0021047276,4.247463e-7,0.98316544,0.0038421394,0.00008016566,0.0074902284],"study_design_scores_gemma":[0.015062082,0.0074595073,0.06696362,0.00029301076,0.000110429,0.00008130049,0.005122703,0.00021231304,0.89969516,0.0008064109,0.0037068625,0.00048659553],"about_ca_topic_score_codex":0.0001599208,"about_ca_topic_score_gemma":0.000013242037,"teacher_disagreement_score":0.08347027,"about_ca_system_score_codex":0.000048487043,"about_ca_system_score_gemma":0.000034436755,"threshold_uncertainty_score":0.99951303},"labels":[],"label_agreement":null},{"id":"W2316200901","doi":"10.4161/cc.29335","title":"Cellular senescence and protein degradation","year":2014,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Cancer Institute","keywords":"Ubiquitin; Proteasome; Biology; Senescence; Protein degradation; Autophagy; Cell biology; Carcinogenesis; F-box protein; Ubiquitin ligase; Ubiquitin-Protein Ligases; Biochemistry; Gene; Apoptosis","score_opus":0.005323866538202365,"score_gpt":0.21237334422825035,"score_spread":0.207049477690048,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2316200901","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98876286,0.0003686561,0.0036896379,0.00015900852,0.000027376696,0.00017403175,4.881996e-7,0.00004080288,0.006777159],"genre_scores_gemma":[0.99676216,0.000015981097,0.00052839617,0.00024324442,0.00007898028,0.000009080339,0.000008450797,0.000009062134,0.0023446279],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99963844,0.000018047002,0.000063485,0.00011527045,0.00007683375,0.000087904904],"domain_scores_gemma":[0.9997326,0.000008908007,0.000021942999,0.00014212236,0.000015816691,0.00007857836],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006348495,0.000054165015,0.00007203151,0.000018633848,0.000039375373,0.000007821658,0.000024120654,0.000031979827,0.0000809135],"category_scores_gemma":[0.0000101656215,0.00004647126,0.000019146668,0.0000389794,0.000027554312,0.00003379273,0.000009364746,0.000044116605,0.000065187174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000430453,0.000099835845,0.0027620657,0.00009585726,0.0000067866204,0.0000117718855,0.00010777549,0.0000012154167,0.9832079,0.00061588414,0.00017652308,0.01287134],"study_design_scores_gemma":[0.00092116615,0.00011803229,0.0126710795,0.000037962094,0.000024670282,0.0000038299668,0.00002735066,0.0021202555,0.9739295,0.0011615582,0.008895865,0.0000887124],"about_ca_topic_score_codex":0.0000097430875,"about_ca_topic_score_gemma":3.7312677e-7,"teacher_disagreement_score":0.012782628,"about_ca_system_score_codex":0.000006895998,"about_ca_system_score_gemma":0.000013097867,"threshold_uncertainty_score":0.1895043},"labels":[],"label_agreement":null},{"id":"W2317848129","doi":"10.4161/auto.25880","title":"Signalphagy","year":2013,"lang":"hu","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Nautical Research Society","funders":"National Institute of General Medical Sciences","keywords":"Biology; Cytokinesis; Autophagy; Cell biology; Signal transduction; RHOA; Motility; Cell; Cell division; Genetics; Apoptosis","score_opus":0.007331704918242937,"score_gpt":0.23879842799374756,"score_spread":0.23146672307550462,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2317848129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87212706,0.042104486,0.000378958,0.002482726,0.002747222,0.0019200987,0.000040971514,0.00051990367,0.077678554],"genre_scores_gemma":[0.933308,0.00091116806,0.0002478272,0.006342001,0.0017332687,0.00016153863,0.000054267904,0.000123644,0.057118256],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9966333,0.00015797277,0.0007236011,0.00074216234,0.0006346536,0.001108345],"domain_scores_gemma":[0.997428,0.00019109402,0.00022143606,0.0010807157,0.0002502736,0.00082845107],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00020854623,0.00058218726,0.0007758794,0.0002192722,0.00022557948,0.00014895448,0.00042661274,0.00041001578,0.10058671],"category_scores_gemma":[0.0000959513,0.0005262089,0.00043698362,0.00044521037,0.00028365132,0.0004101692,0.00012608238,0.000524625,0.061141733],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046237282,0.00438115,0.0042108223,0.0010232509,0.003730895,0.002538767,0.0038444311,0.000037560167,0.14874537,0.026955223,0.38639292,0.41767725],"study_design_scores_gemma":[0.014750673,0.003077908,0.42644405,0.0010194565,0.0017725881,0.0003559798,0.0013426734,0.008136048,0.2874105,0.024008736,0.2289228,0.0027585954],"about_ca_topic_score_codex":0.0004882579,"about_ca_topic_score_gemma":0.000002162814,"teacher_disagreement_score":0.42223322,"about_ca_system_score_codex":0.00014890726,"about_ca_system_score_gemma":0.00040719373,"threshold_uncertainty_score":0.99971896},"labels":[],"label_agreement":null},{"id":"W2322556561","doi":"10.1083/jcb.201507112","title":"The position of lysosomes within the cell determines their luminal pH","year":2016,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":607,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"National Institutes of Health; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Position (finance); Cell biology; Chemistry; Cell; Biophysics; Biology; Business; Biochemistry","score_opus":0.009316623234949228,"score_gpt":0.25184155499443756,"score_spread":0.24252493175948833,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2322556561","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99077153,0.0041670445,0.000112447284,0.0034665454,0.00033457656,0.00010939115,0.000005213944,0.0000041281864,0.0010291376],"genre_scores_gemma":[0.996832,0.001662776,0.000020413192,0.0004340759,0.00043258147,0.0000013980283,6.0254376e-7,0.000008656079,0.00060749805],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903905,0.00029635394,0.0003636329,0.000053839136,0.000104552986,0.00014257962],"domain_scores_gemma":[0.9982723,0.00073790277,0.0005363659,0.00025849196,0.00014838397,0.000046567297],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074153114,0.00010069035,0.00021093323,0.00003448911,0.00012209425,0.0000043098444,0.0003106035,0.00006014087,0.00004549078],"category_scores_gemma":[0.000038469756,0.000026871765,0.00014755384,0.00005701849,0.0004252261,0.000032939726,0.000028749206,0.00014259643,0.000010340939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010745934,0.00007280037,0.0006680154,0.000009738648,0.0000868366,0.000007512477,0.00053925556,0.0000011612218,0.9910757,0.00014619625,0.00028041113,0.0060378136],"study_design_scores_gemma":[0.0011373118,0.0010295748,0.0052502425,0.000052105806,0.00016508858,0.00025248935,0.00046063898,0.000010578428,0.98467356,0.004627973,0.002295098,0.000045333658],"about_ca_topic_score_codex":0.000004297242,"about_ca_topic_score_gemma":0.0000033072006,"teacher_disagreement_score":0.0064021,"about_ca_system_score_codex":0.000017090273,"about_ca_system_score_gemma":0.0001006695,"threshold_uncertainty_score":0.15667634},"labels":[],"label_agreement":null},{"id":"W2322693563","doi":"10.1139/cjpp-2014-0271","title":"Pinosylvin at a high concentration induces AMPK-mediated autophagy for preventing necrosis in bovine aortic endothelial cells","year":2014,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Dankook University","keywords":"Autophagy; Propidium iodide; Apoptosis; AMPK; Cell biology; Programmed cell death; Annexin; Necrosis; Biology; Chemistry; Biochemistry; Protein kinase A; Kinase","score_opus":0.01136401931611496,"score_gpt":0.27269882110556853,"score_spread":0.26133480178945356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2322693563","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99759376,0.00049681135,0.000022945567,0.0006444594,0.0008855003,0.00028008953,0.000041813597,0.000004953324,0.000029665618],"genre_scores_gemma":[0.99664605,0.00012576926,0.000081313636,0.0024359059,0.0005585947,0.00001600348,0.000028617074,0.000012748367,0.00009501876],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891776,0.0001714128,0.00036816188,0.00015420001,0.000045015087,0.00034345186],"domain_scores_gemma":[0.99896103,0.0002710319,0.00024038542,0.00005799746,0.00008786489,0.00038166862],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024527454,0.0001247226,0.00038752306,0.00014311595,0.000107003965,0.00000548401,0.00007992165,0.00014330824,0.0008797513],"category_scores_gemma":[0.00006277135,0.00011152065,0.0000767882,0.000081491526,0.00017121372,0.000067364694,0.000008463562,0.0002104726,0.000005354571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000662805,0.000053677675,0.0020299426,0.000082790415,0.00012068618,0.000034510245,0.0003051175,0.000022152391,0.9944841,0.000094351126,0.0010230397,0.0010867977],"study_design_scores_gemma":[0.008327359,0.0015549911,0.0648438,0.00005384661,0.00024100508,0.00006508978,0.000026440324,0.0011196164,0.91681975,0.0021546246,0.0046348516,0.00015859441],"about_ca_topic_score_codex":0.00037673494,"about_ca_topic_score_gemma":0.0004398069,"teacher_disagreement_score":0.07766435,"about_ca_system_score_codex":0.000095306124,"about_ca_system_score_gemma":0.00050466007,"threshold_uncertainty_score":0.963266},"labels":[],"label_agreement":null},{"id":"W2323877858","doi":"10.1097/00054725-200912002-00168","title":"The role of ATG16L1 in bacterial-induced autophagy","year":2009,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"ATG16L1; Autophagy; Shigella flexneri; Biology; Small hairpin RNA; Sequestosome 1; Molecular biology; Cell culture; Chemistry; Gene knockdown; Apoptosis; Gene; Genetics","score_opus":0.006779365986061168,"score_gpt":0.2500119130923681,"score_spread":0.24323254710630693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2323877858","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934734,0.0033759444,8.1560177e-7,0.00022416192,0.00014430222,0.00038504344,0.000017830673,0.0000884281,0.002290091],"genre_scores_gemma":[0.9991085,0.00017876727,0.0000104231485,0.0002844243,0.00021768264,0.00003116512,0.000017141974,0.00001816697,0.00013370969],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987023,0.00007526974,0.00042745235,0.00021157265,0.00028181772,0.00030161822],"domain_scores_gemma":[0.99899024,0.00009239693,0.00013183466,0.000508499,0.00006669779,0.0002103494],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011472661,0.00018115262,0.0002673608,0.00009628389,0.00008848605,0.000023673692,0.0001865922,0.00008350572,0.00018849515],"category_scores_gemma":[0.00011057094,0.00013064648,0.00017849315,0.00013231194,0.00009279686,0.000121146106,0.00002365294,0.00011587856,0.000040508883],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007987544,0.0024810098,0.31928173,0.00021549832,0.00041427993,0.0014241404,0.0011836181,0.00003437323,0.42125008,0.02236173,0.0012479038,0.2221181],"study_design_scores_gemma":[0.0014512135,0.00016423449,0.95444137,0.00009940833,0.00006292082,0.000006121392,0.00013225715,0.0000994202,0.0334606,0.0055545797,0.0043926565,0.00013520326],"about_ca_topic_score_codex":0.00000985148,"about_ca_topic_score_gemma":0.0000062356016,"teacher_disagreement_score":0.6351597,"about_ca_system_score_codex":0.000051777693,"about_ca_system_score_gemma":0.00027598673,"threshold_uncertainty_score":0.53276086},"labels":[],"label_agreement":null},{"id":"W2326828834","doi":"10.4161/auto.20828","title":"Targeting autophagy","year":2012,"lang":"hu","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Victoria; Simon Fraser University; Burnaby Hospital; BC Cancer Agency","funders":"Canadian Institutes of Health Research; Merck Canada; Takeda Oncology; Simon Fraser University; University of Glasgow","keywords":"Autophagy; Biology; Cancer; Basic research; Drug development; Clinical trial; Disease; Translational research; Drug discovery; Mechanism (biology); Cancer research; Bioinformatics; Drug; Pharmacology; Biotechnology; Genetics; Medicine; Internal medicine; Library science; Apoptosis","score_opus":0.017767958305325383,"score_gpt":0.2947497927237901,"score_spread":0.2769818344184647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2326828834","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.73938495,0.2071782,0.0008292671,0.00075511535,0.010502683,0.0012894078,0.000100753176,0.0008603885,0.039099243],"genre_scores_gemma":[0.9634772,0.001966395,0.0007406946,0.0039464207,0.0081278,0.00007148982,0.000152662,0.00021886494,0.021298496],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9944673,0.00032005954,0.0010830276,0.0007632457,0.00091056735,0.0024557803],"domain_scores_gemma":[0.99650586,0.00028385405,0.00041331924,0.0011517601,0.00017264749,0.0014725338],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001027955,0.0008546909,0.0010841762,0.00029634673,0.00046050872,0.00009358249,0.0004938983,0.0006193381,0.019053144],"category_scores_gemma":[0.0003231379,0.0008156454,0.0005644015,0.0006334689,0.00031085417,0.00073300564,0.0002363688,0.0008728272,0.012843287],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002528815,0.017159855,0.06513429,0.0035337224,0.0086870445,0.0036631431,0.031836126,0.00018633269,0.2345361,0.11584527,0.29432428,0.22256503],"study_design_scores_gemma":[0.010111942,0.0010898524,0.22543722,0.0007652744,0.0022955113,0.00037727036,0.0017069391,0.0037651013,0.20304745,0.0013901007,0.5472711,0.0027422572],"about_ca_topic_score_codex":0.00009853307,"about_ca_topic_score_gemma":6.1577765e-7,"teacher_disagreement_score":0.2529468,"about_ca_system_score_codex":0.00032422066,"about_ca_system_score_gemma":0.000429709,"threshold_uncertainty_score":0.99942946},"labels":[],"label_agreement":null},{"id":"W2329207647","doi":"10.1158/1538-7445.am2013-1684","title":"Abstract 1684: Autophagy inhibition as an effective strategy for sensitizing triple-negative breast cancer cells to chemotherapy.","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Autophagy; Triple-negative breast cancer; Cancer research; Breast cancer; Chemotherapy; In vivo; Cancer; Medicine; Cell culture; Biology; Pharmacology; Oncology; Internal medicine; Apoptosis","score_opus":0.047524475868695445,"score_gpt":0.423418160117536,"score_spread":0.37589368424884056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2329207647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99041986,0.00040270537,0.00006642936,0.002371026,0.0001912419,0.005175164,0.00025539592,0.00009161496,0.0010265845],"genre_scores_gemma":[0.99142444,0.0002401598,0.00011074977,0.0016169613,0.0010710363,0.0039818417,0.00003380486,0.00008601236,0.0014349865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99758947,0.00014644695,0.00026327392,0.0006197097,0.00060123764,0.0007798843],"domain_scores_gemma":[0.99757594,0.0002798335,0.00006971694,0.00037218424,0.0010861994,0.0006161086],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005330774,0.00025169778,0.00038491507,0.00027505832,0.00027280068,0.00011823646,0.00012333374,0.00016834897,0.003845379],"category_scores_gemma":[0.00004963108,0.00021810255,0.00013164949,0.00048392444,0.00016344707,0.00033795464,0.000032279393,0.0004646519,0.00028181495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026685363,0.0003188435,0.00009356262,0.00023707411,0.00023656583,0.000058381775,0.0014920036,0.00010665157,0.8359041,0.00016437995,0.0071286852,0.1515912],"study_design_scores_gemma":[0.0043975203,0.0009868859,0.09378626,0.00038863055,0.000032221644,0.000017713104,0.00087222666,0.00034199975,0.8959726,0.0024031976,0.00052775716,0.0002729646],"about_ca_topic_score_codex":0.007764905,"about_ca_topic_score_gemma":0.0001687455,"teacher_disagreement_score":0.15131824,"about_ca_system_score_codex":0.0006840535,"about_ca_system_score_gemma":0.0006589271,"threshold_uncertainty_score":0.9988425},"labels":[],"label_agreement":null},{"id":"W2329436416","doi":"10.1139/bcb-2014-0001","title":"Interaction of Grb2 SH3 domain with UVRAG in an Alzheimer’s disease–like scenario","year":2014,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"GRB2; Signal transducing adaptor protein; SH3 domain; Cell biology; Biology; Proto-oncogene tyrosine-protein kinase Src; Signal transduction; Chemistry","score_opus":0.01090175913712845,"score_gpt":0.265443482388267,"score_spread":0.25454172325113855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2329436416","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962902,0.0017029485,0.000043275424,0.00008589621,0.00004078996,0.0000858317,0.000007587194,0.00001415174,0.001729324],"genre_scores_gemma":[0.99921733,0.00009593475,0.000117956755,0.00024228629,0.00009091461,0.000009585008,0.00013359029,0.000007451293,0.00008495358],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994386,0.000036366786,0.00013454842,0.00022333993,0.000039884762,0.00012725711],"domain_scores_gemma":[0.9995517,0.000022500595,0.000062521576,0.0002011733,0.000023602568,0.00013846857],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007256248,0.00010392612,0.00017366423,0.000027785056,0.00002074499,0.000003167527,0.000047694688,0.00009906192,0.000080228085],"category_scores_gemma":[0.000005416689,0.00007859681,0.000028362188,0.00004862116,0.00013709882,0.000024192155,0.00001539067,0.000090423586,0.0000023754558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002545127,0.000549267,0.10131841,0.00015529217,0.00006183616,0.000024705598,0.00014271037,0.0000024075537,0.88681823,0.00013708952,0.00007078911,0.008174162],"study_design_scores_gemma":[0.0032502043,0.0009610734,0.04717102,0.00014339437,0.00015130632,0.000022192262,0.00027921802,0.00019460572,0.941231,0.0005687716,0.005789163,0.00023803933],"about_ca_topic_score_codex":0.000017687105,"about_ca_topic_score_gemma":0.0000035633338,"teacher_disagreement_score":0.05441281,"about_ca_system_score_codex":0.000009424094,"about_ca_system_score_gemma":0.000048489434,"threshold_uncertainty_score":0.32050848},"labels":[],"label_agreement":null},{"id":"W2330125136","doi":"10.1016/j.reprotox.2016.03.044","title":"Hydroxychloroquine attenuates cigarette smoke induced autophagic signaling in the mouse ovary","year":2016,"lang":"en","type":"article","venue":"Reproductive Toxicology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University Medical Centre; McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Ovary; BECN1; Hydroxychloroquine; Chloroquine; Smoke; Andrology; Chemistry; Apoptosis; Medicine; Endocrinology; Biology; Internal medicine; Pharmacology; Immunology; Biochemistry","score_opus":0.03999181558748096,"score_gpt":0.30814954157955515,"score_spread":0.2681577259920742,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2330125136","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9767055,0.00074661936,0.000023805287,0.0206076,0.00021512352,0.0007239549,0.0000079228785,0.00010863844,0.00086085114],"genre_scores_gemma":[0.9943196,0.00007102084,0.00005004436,0.0036306053,0.00077249564,0.00013899528,0.000010705468,0.00003660695,0.000969923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99783003,0.00029883112,0.0003688412,0.00077880966,0.0002641869,0.00045926886],"domain_scores_gemma":[0.99843156,0.00026729234,0.00013143398,0.0009785965,0.00010088777,0.00009023546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008653962,0.00023701173,0.0004202429,0.00018449694,0.0000883346,0.000009592757,0.000244985,0.00018163356,0.00052661303],"category_scores_gemma":[0.00049160584,0.00013108272,0.00012243126,0.00034361475,0.00022635877,0.00012639647,0.00005974033,0.00031759695,0.000082497136],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006131584,0.0006048819,0.010547463,0.000017820512,0.0001962169,0.0004067676,0.0009915766,0.000004016122,0.97590137,0.0009043575,0.00073222147,0.009080162],"study_design_scores_gemma":[0.0029851478,0.0010751202,0.18542802,0.00005783387,0.000105177554,0.00025221377,0.00024624466,0.000011566135,0.8039279,0.0038822892,0.0017657719,0.00026270788],"about_ca_topic_score_codex":0.000024658453,"about_ca_topic_score_gemma":0.0000045913093,"teacher_disagreement_score":0.17488056,"about_ca_system_score_codex":0.00014212025,"about_ca_system_score_gemma":0.00012665044,"threshold_uncertainty_score":0.57660437},"labels":[],"label_agreement":null},{"id":"W2331649103","doi":"10.1139/bcb-2013-0029","title":"Clinorotation enhances autophagy in vascular endothelial cells","year":2013,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autophagy; Cell biology; Umbilical vein; Homeostasis; Endothelial stem cell; Spaceflight; Chemistry; Biology; Apoptosis; Biochemistry; In vitro","score_opus":0.006068709916252222,"score_gpt":0.242467730669906,"score_spread":0.2363990207536538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2331649103","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933416,0.0025065034,0.000020298618,0.0000537731,0.00008008706,0.00017117527,0.0000074529985,0.00002250317,0.0037965793],"genre_scores_gemma":[0.99757177,0.0008290827,0.00014255744,0.00031750495,0.00015176821,0.000044150293,0.00004782101,0.000006209137,0.00088913227],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993929,0.000024039187,0.00015627926,0.00022339499,0.00003865708,0.00016468267],"domain_scores_gemma":[0.99968326,0.000037531787,0.00004177153,0.00013386877,0.00002301375,0.00008052552],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005496188,0.00010184587,0.00016143544,0.000023705035,0.000025224052,0.0000066444336,0.000044420067,0.00016183087,0.00051862496],"category_scores_gemma":[0.0000119795295,0.000084304564,0.000040532494,0.00004637984,0.00009095493,0.000023348268,0.000015161581,0.000088523324,0.00006548539],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035166177,0.00011594228,0.0011224388,0.000060964758,0.000014422176,0.0000060324496,0.000041822754,2.239629e-7,0.99335986,0.00002108555,0.00007480535,0.005147235],"study_design_scores_gemma":[0.0012653789,0.00010614468,0.004747229,0.000012625646,0.000014923897,0.0000028418085,0.00005744741,0.00005011313,0.990849,0.00035194846,0.002454671,0.00008763324],"about_ca_topic_score_codex":0.00004268528,"about_ca_topic_score_gemma":4.3230975e-7,"teacher_disagreement_score":0.0050596017,"about_ca_system_score_codex":0.000012173905,"about_ca_system_score_gemma":0.000040352636,"threshold_uncertainty_score":0.5678579},"labels":[],"label_agreement":null},{"id":"W2331727595","doi":"10.1080/23723556.2015.1046579","title":"PINK1 deficiency enhances autophagy and mitophagy induction","year":2015,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Mitophagy; PINK1; Autophagy; Mitochondrion; Cell biology; Biology; Programmed cell death; PTEN; Downregulation and upregulation; Genetics; Gene; Apoptosis; PI3K/AKT/mTOR pathway; Signal transduction","score_opus":0.024231734394840204,"score_gpt":0.30623912455325586,"score_spread":0.28200739015841564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2331727595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.970058,0.014869481,0.0048023537,0.00062533526,0.00055021717,0.00033514024,0.0000017946262,0.000106842286,0.008650827],"genre_scores_gemma":[0.99558216,0.00013220591,0.0017063534,0.0017173369,0.0002097965,0.000039197574,0.000027881622,0.000032207787,0.0005528542],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998523,0.00015226698,0.00027774772,0.00041928483,0.0002809331,0.00034676082],"domain_scores_gemma":[0.9990747,0.000025555742,0.000104319355,0.00033282986,0.00012456563,0.00033803328],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027300863,0.00020466922,0.00038151935,0.00014313763,0.00007311336,0.00001764423,0.00010541144,0.00026276495,0.00010419151],"category_scores_gemma":[0.0000820651,0.0001880403,0.000096839925,0.00021708873,0.00021221113,0.0000755709,0.000062987,0.00023412454,0.00012259945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002619522,0.00042603744,0.00030308697,0.00003912522,0.0000792249,0.001652466,0.00048733162,0.000007533113,0.97339374,0.0016398372,0.00051638024,0.021193285],"study_design_scores_gemma":[0.0025079881,0.0019509087,0.0012417724,0.000018345298,0.00014161228,0.0003828395,0.00027479933,0.00015080409,0.9486242,0.0027426998,0.041748658,0.00021539145],"about_ca_topic_score_codex":0.00003809925,"about_ca_topic_score_gemma":0.0000026808382,"teacher_disagreement_score":0.04123228,"about_ca_system_score_codex":0.00014265224,"about_ca_system_score_gemma":0.00040197547,"threshold_uncertainty_score":0.76680607},"labels":[],"label_agreement":null},{"id":"W2333839776","doi":"10.1139/z11-075","title":"Expression of autophagy-related genes in the anterior silk gland of the silkworm (<i>Bombyx mori</i>) during metamorphosis","year":2011,"lang":"en","type":"article","venue":"Canadian Journal of Zoology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Bombyx mori; Biology; Autophagy; Metamorphosis; Bombyx; Gene; Cell biology; SILK; Western blot; Larva; Messenger RNA; Gene expression; Molecular biology; Genetics; Botany; Apoptosis","score_opus":0.015225271104632633,"score_gpt":0.22419746506047453,"score_spread":0.2089721939558419,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2333839776","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99171257,0.007104266,0.0000038447542,0.00027327298,0.00033126373,0.00014231983,0.000010176961,0.0000018330209,0.00042046845],"genre_scores_gemma":[0.9993465,0.00017618873,0.000073822775,0.00023758956,0.0000540364,0.0000024268381,5.850143e-7,0.000011681492,0.000097168435],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9988283,0.00016041716,0.00055762945,0.000088350585,0.00014505275,0.00022027997],"domain_scores_gemma":[0.99896544,0.000052264986,0.00042069255,0.00028058374,0.00010608401,0.0001749364],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031468636,0.00010933641,0.000401114,0.0002334001,0.000056997476,0.0000030880383,0.00033120194,0.00011145811,0.00047868484],"category_scores_gemma":[0.000075719225,0.00005970053,0.00019442929,0.00022021783,0.00023123181,0.00005750562,0.000014683157,0.0002550551,0.0000015796815],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00062888075,0.00018925415,0.75284606,0.000112664835,0.00035819586,0.0015238915,0.009583331,0.000017063438,0.23267113,0.00021803954,0.00017270232,0.0016787875],"study_design_scores_gemma":[0.001400028,0.0002102043,0.8020242,0.00022345237,0.00013113406,0.00060596835,0.00041666496,0.000005864642,0.19448866,0.00038205337,0.00006230535,0.000049497445],"about_ca_topic_score_codex":0.0024668362,"about_ca_topic_score_gemma":0.0029747554,"teacher_disagreement_score":0.049178116,"about_ca_system_score_codex":0.00004390907,"about_ca_system_score_gemma":0.00052286667,"threshold_uncertainty_score":0.52412635},"labels":[],"label_agreement":null},{"id":"W2334578081","doi":"10.1017/s031716710001218x","title":"2-Methoxyestradiol Attenuates Autophagy Activation After Global Ischemia","year":2011,"lang":"en","type":"article","venue":"Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Science and Technology Commission of Shanghai Municipality","keywords":"Autophagy; Ischemia; Western blot; TUNEL assay; BECN1; Medicine; Apoptosis; Pharmacology; Chemistry; Immunohistochemistry; Internal medicine; Biochemistry; Gene","score_opus":0.043676398221714034,"score_gpt":0.29042231588121403,"score_spread":0.2467459176595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2334578081","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99005795,0.0011910717,0.000064338135,0.0017284923,0.00061018683,0.00015812716,0.000010628849,0.000025988295,0.0061532436],"genre_scores_gemma":[0.989492,0.00018258659,0.0041581984,0.005780203,0.00034299394,0.0000041665703,3.4039832e-7,0.000010734276,0.000028767465],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9963943,0.0004885008,0.0007772003,0.00047898342,0.00069925265,0.0011617811],"domain_scores_gemma":[0.99631,0.00018965812,0.0005899475,0.0001698216,0.00042138144,0.0023192028],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0020727029,0.00033090755,0.0005140804,0.0005143373,0.0012314623,0.00026476182,0.0011051669,0.00023049532,0.00081685797],"category_scores_gemma":[0.0010926662,0.00021758002,0.00032810887,0.0011790856,0.0049991314,0.000986977,0.00003858152,0.001017178,0.000009064695],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047995913,0.00007862048,0.9788934,0.0000102617905,0.000044693494,0.0123095475,0.00047659027,0.00007778545,0.00022437748,0.0010347904,0.00051482115,0.0058551817],"study_design_scores_gemma":[0.0006032539,0.04916245,0.88077056,0.00007635597,0.00010523753,0.037345346,0.00020994163,0.00028091864,0.0036271063,0.026130296,0.0013451807,0.0003433806],"about_ca_topic_score_codex":0.0009770325,"about_ca_topic_score_gemma":0.00414795,"teacher_disagreement_score":0.098122835,"about_ca_system_score_codex":0.00027463638,"about_ca_system_score_gemma":0.0040621944,"threshold_uncertainty_score":0.9977087},"labels":[],"label_agreement":null},{"id":"W2338164967","doi":"10.1016/j.mce.2016.04.006","title":"Lipocalin-2 inhibits autophagy and induces insulin resistance in H9c2 cells","year":2016,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Autophagy; Insulin resistance; ATG5; Protein kinase B; Lipocalin; Insulin; Internal medicine; PI3K/AKT/mTOR pathway; Endocrinology; Cell biology; Biology; Chemistry; Phosphorylation; Signal transduction; Medicine; Apoptosis; Biochemistry","score_opus":0.007835026568046057,"score_gpt":0.23387661191237702,"score_spread":0.22604158534433097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2338164967","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9734951,0.022976689,0.0005398749,0.001207974,0.0000882273,0.00023351336,0.000006418806,0.00004813278,0.0014040475],"genre_scores_gemma":[0.99629617,0.0016113629,0.00026711082,0.00091448176,0.00004376213,0.00002578107,0.0000052841015,0.000026007594,0.00081002485],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998673,0.000098710065,0.00026179416,0.00043235678,0.0001266953,0.00040742417],"domain_scores_gemma":[0.9994342,0.000048845395,0.000054152853,0.00027299995,0.000030588206,0.0001592488],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000725453,0.00019635189,0.00033808712,0.00016135689,0.00004236055,0.000010776655,0.0000695944,0.00013370918,0.000077871395],"category_scores_gemma":[0.000031652293,0.00014606382,0.000053433163,0.00012170138,0.0002253747,0.00004917866,0.000075032855,0.00016006104,0.000026384947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021035013,0.00011752557,0.0008799975,0.000054728833,0.00005332294,0.0021965513,0.00014374802,1.7732194e-7,0.9763351,0.006754714,0.000046053985,0.013207737],"study_design_scores_gemma":[0.0033684752,0.00016943876,0.0052254586,0.000095690404,0.000040025167,0.000076479715,0.0000313221,0.0000046320442,0.98005325,0.0036271722,0.007127287,0.00018077665],"about_ca_topic_score_codex":0.000019951427,"about_ca_topic_score_gemma":0.000011636673,"teacher_disagreement_score":0.022801062,"about_ca_system_score_codex":0.000024985151,"about_ca_system_score_gemma":0.000050477298,"threshold_uncertainty_score":0.59563094},"labels":[],"label_agreement":null},{"id":"W2340086547","doi":"10.1515/hsz-2016-0137","title":"Mechanisms of mitophagy: putting the powerhouse into the doghouse","year":2016,"lang":"en","type":"review","venue":"Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Servier; Cancer Research Society; Tenovus; Cancer Research UK; Royal Society","keywords":"Mitophagy; Chemistry; Autophagy; Biochemistry; Apoptosis","score_opus":0.04599172131665078,"score_gpt":0.33770297027339474,"score_spread":0.29171124895674394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2340086547","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007258253,0.9971813,0.00004532941,0.00024980403,0.00010804682,0.00050265033,0.00003287959,0.00009523954,0.0010589022],"genre_scores_gemma":[0.0037693402,0.9942849,0.000103830534,0.00029625598,0.00048442945,0.00011496236,0.000042105956,0.00004002142,0.00086412847],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984238,0.000116654024,0.0005528818,0.00039867515,0.0002215579,0.00028643152],"domain_scores_gemma":[0.9979559,0.00057953957,0.0004100587,0.00088254485,0.000055805045,0.00011610566],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003637968,0.00038836646,0.0011262815,0.000013162053,0.00011511042,0.000013019224,0.00064807036,0.000597972,0.0007329342],"category_scores_gemma":[0.00033578725,0.00012453194,0.00083507126,0.0001456813,0.00036864963,0.000011473967,0.0001947857,0.00045533842,0.00007623377],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044779717,0.00018302017,0.00000589299,0.005234766,0.0006286604,0.0000845324,0.00005728306,9.4817185e-9,0.008631146,0.00045421012,0.00074868224,0.983927],"study_design_scores_gemma":[0.00030719693,0.00008181087,0.000015930864,0.004458789,0.00039372794,0.00010164819,0.00003435846,1.7390032e-7,0.008588751,0.002687775,0.9831398,0.00019000571],"about_ca_topic_score_codex":0.0000042585534,"about_ca_topic_score_gemma":7.741102e-8,"teacher_disagreement_score":0.983737,"about_ca_system_score_codex":0.00006062087,"about_ca_system_score_gemma":0.00018657018,"threshold_uncertainty_score":0.8025116},"labels":[],"label_agreement":null},{"id":"W2340680032","doi":"10.1038/ni.3434","title":"Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism","year":2016,"lang":"en","type":"article","venue":"Nature Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":366,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Center for Advancing Translational Sciences; National Institute of General Medical Sciences; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; Biology; TFEB; ATG5; Lipid metabolism; Intracellular parasite; Phagosome; Lipid droplet; Gene silencing; Intracellular; Gene; Biochemistry; Apoptosis","score_opus":0.006103796407496301,"score_gpt":0.2674556356625804,"score_spread":0.2613518392550841,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2340680032","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94529355,0.029988972,0.0000118066855,0.022270156,0.0011895271,0.00049844536,0.000027327074,0.00014519076,0.0005750337],"genre_scores_gemma":[0.9912078,0.0016414347,0.00013725819,0.0052808737,0.00060172426,0.000099350895,0.000008005064,0.00003546774,0.0009880996],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985453,0.00012255443,0.0002500949,0.00046392277,0.0001785726,0.0004395448],"domain_scores_gemma":[0.9987107,0.00016669183,0.00008336744,0.0007647514,0.00013383468,0.00014065785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021214347,0.0002491741,0.00041072813,0.0001344307,0.00013135571,0.000027605773,0.00023374766,0.0006076843,0.0002689082],"category_scores_gemma":[0.00026747832,0.00012486201,0.00012234657,0.0002657372,0.00027280557,0.000094205,0.00013929888,0.0005986628,0.00014057619],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00093525485,0.00020956999,0.00089747645,0.000021001533,0.0009297279,0.00007705939,0.0006236463,1.8209033e-8,0.8609247,0.0032189623,0.0024593717,0.12970318],"study_design_scores_gemma":[0.0020302257,0.000425338,0.38865635,0.000078972545,0.00022719304,0.00027545233,0.0000924581,3.6846328e-7,0.25528678,0.0004083756,0.35228693,0.0002315594],"about_ca_topic_score_codex":0.00003585206,"about_ca_topic_score_gemma":0.0000059908625,"teacher_disagreement_score":0.60563797,"about_ca_system_score_codex":0.000040649647,"about_ca_system_score_gemma":0.000076605604,"threshold_uncertainty_score":0.5091725},"labels":[],"label_agreement":null},{"id":"W2341405266","doi":"10.1111/jcmm.12859","title":"Autophagy dysfunction and regulatory cystatin C in macrophage death of atherosclerosis","year":2016,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Magnus Bergvalls Stiftelse; Kungliga Fysiografiska Sällskapet i Lund; National Institute on Aging; Crafoordska Stiftelsen; Torsten Söderbergs Stiftelse","keywords":"Autophagy; Cystatin C; Macrophage; Cystatin; Medicine; Biology; Immunology; Internal medicine; Apoptosis; Biochemistry","score_opus":0.009573552897743923,"score_gpt":0.24477392573941725,"score_spread":0.23520037284167333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2341405266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9776458,0.013143873,0.007970061,0.0007763583,0.000107007916,0.00011787841,0.0000018764058,0.00000499803,0.00023212735],"genre_scores_gemma":[0.99710214,0.0019640967,0.00033233617,0.00033913765,0.000096970405,0.0000014207103,0.0000012453477,0.000018084098,0.0001445456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988423,0.00007251774,0.0004970316,0.00013023609,0.000320105,0.0001378369],"domain_scores_gemma":[0.9992216,0.000053255648,0.00027159735,0.00015033067,0.0001106638,0.00019252153],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046805895,0.00012958534,0.00045350753,0.0002192867,0.000018229648,0.0000025727982,0.00004527447,0.00008178531,0.00010883366],"category_scores_gemma":[0.000100997524,0.00007545568,0.00007221633,0.00009329927,0.00017028679,0.00006255982,0.00001636293,0.00011826229,6.732243e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003554809,0.000082449085,0.0060938415,0.00009023617,0.000087800516,0.00038137232,0.0002244161,5.506063e-7,0.9801525,0.00068717106,0.00004993655,0.011794252],"study_design_scores_gemma":[0.012077423,0.0021818988,0.25274414,0.0015879746,0.0003140193,0.0003769468,0.000157457,0.00003551243,0.7275509,0.0020560445,0.000794216,0.00012345226],"about_ca_topic_score_codex":0.000015162699,"about_ca_topic_score_gemma":4.9018394e-7,"teacher_disagreement_score":0.2526016,"about_ca_system_score_codex":0.000031129133,"about_ca_system_score_gemma":0.00005908056,"threshold_uncertainty_score":0.30769935},"labels":[],"label_agreement":null},{"id":"W2344580693","doi":"10.1093/femsyr/fov032","title":"Inhibition of stress mediated cell death by human lactate dehydrogenase B in yeast","year":2015,"lang":"en","type":"article","venue":"FEMS Yeast Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University; Royal Military College of Canada; Queen's University; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Lactate dehydrogenase; Programmed cell death; Yeast; Extracellular; Autophagy; Intracellular; Biochemistry; Mutant; Lactic acid; Cell biology; Apoptosis; Enzyme; Bacteria; Genetics; Gene","score_opus":0.07870977449973685,"score_gpt":0.3787937919066433,"score_spread":0.3000840174069065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2344580693","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896817,0.0007241022,0.0000058333962,0.00012084166,0.000028013474,0.00039842085,0.00016369497,0.000029941028,0.008847424],"genre_scores_gemma":[0.99797374,0.00005543564,0.000017397819,0.00003925789,0.000087700944,0.000041074985,0.00043483145,0.000029894885,0.0013206734],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99799603,0.0002050984,0.00027100762,0.00024942006,0.0008572179,0.00042125094],"domain_scores_gemma":[0.9989111,0.000039734896,0.000054036063,0.0003101291,0.00028279648,0.00040224107],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007787475,0.00011737505,0.0002376103,0.0003118342,0.000045877532,0.000014888489,0.00011666352,0.000109014945,0.00023437584],"category_scores_gemma":[0.000100044585,0.00010473388,0.000052013966,0.0004722601,0.00013964219,0.00008124132,0.00006609324,0.00038224817,0.00019080103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010506692,0.0026351782,0.056944344,0.00028298146,0.00006462536,0.0006788914,0.002316585,0.000012702779,0.92369354,0.00021681539,0.011279721,0.0008239433],"study_design_scores_gemma":[0.0073872623,0.0007192319,0.018632691,0.00031257115,0.000019273337,0.000010408908,0.0013587391,0.0004903113,0.9681318,0.0007746833,0.0019674597,0.00019557432],"about_ca_topic_score_codex":0.0007228262,"about_ca_topic_score_gemma":0.00006755834,"teacher_disagreement_score":0.04443825,"about_ca_system_score_codex":0.00013344099,"about_ca_system_score_gemma":0.00027824723,"threshold_uncertainty_score":0.42709237},"labels":[],"label_agreement":null},{"id":"W2344673827","doi":"10.1016/j.ijcard.2016.04.155","title":"Critical role of lysosomes in the dysfunction of human Cardiac Stem Cells obtained from failing hearts","year":2016,"lang":"en","type":"article","venue":"International Journal of Cardiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Fondazione Italiana per la Ricerca sul Cancro; Associazione Italiana per la Ricerca sul Cancro; Beneficentia Stiftung","keywords":"TFEB; Lysosome; Cell biology; Autophagy; Lipofuscin; Proteostasis; Stem cell; Biology; Medicine; Internal medicine; Biochemistry","score_opus":0.014333727686990755,"score_gpt":0.3036357752128981,"score_spread":0.2893020475259073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2344673827","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961361,0.0009509369,0.0005475929,0.0009654285,0.00067874044,0.000056630775,0.00003577139,0.000002583752,0.0006261785],"genre_scores_gemma":[0.9988577,0.00015556673,0.000044438904,0.000104299084,0.0008081036,0.0000015846791,0.0000028051486,0.0000058520664,0.000019658612],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99884695,0.00020052897,0.00045251378,0.000077594676,0.00033650926,0.00008590279],"domain_scores_gemma":[0.9987341,0.0005071126,0.00018059714,0.000113941824,0.00042803574,0.000036219164],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000387435,0.000066396584,0.0003832865,0.00013969155,0.000010690519,0.000003620218,0.00015787559,0.00006696781,0.000047169724],"category_scores_gemma":[0.000081609476,0.000037137303,0.00026984248,0.000036838814,0.0001188846,0.00007557382,0.00001792547,0.00010706171,0.000002151717],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009724367,0.00010443442,0.10006881,0.000010320995,0.0010440556,0.00017394156,0.00052383076,0.000053920507,0.8828149,0.00331075,0.00030302283,0.010619584],"study_design_scores_gemma":[0.005197226,0.00130049,0.5312203,0.0005363502,0.00037507675,0.0002832033,0.002500484,0.000027406331,0.43563357,0.018353678,0.0044271327,0.0001450655],"about_ca_topic_score_codex":0.000016688571,"about_ca_topic_score_gemma":6.3092443e-7,"teacher_disagreement_score":0.4471813,"about_ca_system_score_codex":0.000045164943,"about_ca_system_score_gemma":0.00006879481,"threshold_uncertainty_score":0.15144151},"labels":[],"label_agreement":null},{"id":"W2344690730","doi":"10.1371/journal.pone.0154820","title":"Nicotinate-Curcumin Impedes Foam Cell Formation from THP-1 Cells through Restoring Autophagy Flux","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"University of South China; Construct Program of the Key Discipline in Hunan Province; China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"Autophagy; Foam cell; Lipid droplet; Flux (metallurgy); Colocalization; Chemistry; Curcumin; Cell biology; PI3K/AKT/mTOR pathway; THP1 cell line; Lipid metabolism; Biochemistry; Cholesterol; Cell culture; Biology; Signal transduction; Lipoprotein; Apoptosis","score_opus":0.04630377418727843,"score_gpt":0.24741263448762582,"score_spread":0.2011088603003474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2344690730","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898618,0.0014599654,0.0009460891,0.0005300988,0.00014086747,0.0004118565,0.000043601,0.00023374897,0.006371958],"genre_scores_gemma":[0.9891847,0.00046995058,0.0024145655,0.00043016078,0.0005327013,0.000045988436,0.000052065567,0.000047637084,0.0068222485],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985234,0.00004922129,0.00033131437,0.00029995802,0.00044990034,0.0003461752],"domain_scores_gemma":[0.9989179,0.00015793167,0.000145825,0.00052915246,0.000094615134,0.00015461612],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000100805955,0.00020511827,0.00035362903,0.000059972026,0.00009786313,0.00002244296,0.00014876656,0.00013089085,0.0014213236],"category_scores_gemma":[0.000051213203,0.00014638659,0.00010886997,0.00010708029,0.000052342737,0.00044059122,0.000050730425,0.00013082461,0.0011093824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017340593,0.0012191983,0.0008851799,0.00012881089,0.00017055884,0.0000295875,0.00080647314,2.9347734e-7,0.9932217,0.00014237204,0.0014408042,0.0017816328],"study_design_scores_gemma":[0.0022854647,0.00026099276,0.003495856,0.00054166367,0.00026111896,0.0000014033104,0.000075860095,0.00007162268,0.98938566,0.0020175988,0.0014141537,0.00018861292],"about_ca_topic_score_codex":0.00007952144,"about_ca_topic_score_gemma":0.0000031995362,"teacher_disagreement_score":0.0038360306,"about_ca_system_score_codex":0.00013848332,"about_ca_system_score_gemma":0.000065233566,"threshold_uncertainty_score":0.99966836},"labels":[],"label_agreement":null},{"id":"W2346094555","doi":"10.1139/bcb-2016-0005","title":"RecQL4 regulates autophagy and apoptosis in U2OS cells","year":2016,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China; National Science Foundation","keywords":"Autophagy; Mitophagy; Gene knockdown; Cell biology; Apoptosis; Mitochondrion; PINK1; Knockout mouse; RNA interference; HEK 293 cells; Biology; Phenotype; Parkin; Genome instability; Chemistry; Cancer research; Genetics; Cell culture; DNA damage; RNA; Gene; DNA; Medicine","score_opus":0.006828963017051267,"score_gpt":0.2341719025769556,"score_spread":0.22734293955990434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2346094555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992947,0.004061214,0.0000055471287,0.00035943306,0.00005125277,0.00008125411,0.000013524323,0.000024537238,0.0024562776],"genre_scores_gemma":[0.9944617,0.0019725035,0.000090157424,0.00024994125,0.000085844666,0.000011083939,0.00001156885,0.0000076253555,0.0031095617],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99934876,0.00002002357,0.00014098699,0.00027934572,0.000028452236,0.00018243164],"domain_scores_gemma":[0.9996164,0.000055824083,0.00003858376,0.00016362945,0.000014002362,0.00011157941],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006794057,0.00011655242,0.00018506248,0.000027477876,0.00002659041,0.0000037570737,0.000039604376,0.000204345,0.00017164885],"category_scores_gemma":[0.000013940434,0.00007577965,0.000025000967,0.00004498485,0.00018254513,0.000015709487,0.000032362434,0.000057008743,0.000009509875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013180615,0.00007142952,0.0026104748,0.00006126246,0.00001461769,0.0000072360226,0.000023668812,8.103088e-9,0.9845973,0.000043133135,0.00020997402,0.0122290775],"study_design_scores_gemma":[0.0016137472,0.00012251435,0.00242843,0.000047833262,0.000017790628,0.00001129512,0.000026210897,0.0000032185665,0.99085194,0.0004519436,0.00432148,0.0001036107],"about_ca_topic_score_codex":0.0000071214945,"about_ca_topic_score_gemma":2.1264957e-7,"teacher_disagreement_score":0.012125467,"about_ca_system_score_codex":0.000014240472,"about_ca_system_score_gemma":0.00003081251,"threshold_uncertainty_score":0.30902046},"labels":[],"label_agreement":null},{"id":"W2346811559","doi":"10.1111/tra.12410","title":"Myosins, Actin and Autophagy","year":2016,"lang":"en","type":"review","venue":"Traffic","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Cambridge Institute for Medical Research, University of Cambridge; Wellcome; Medical Research Council; Medical Research Council Canada; British Heart Foundation; Wellcome Trust","keywords":"Cell biology; Biology; Myosin; Autophagy; Autophagosome; Lysosome; Actin; Cytoskeleton; Actin cytoskeleton; Organelle; Actin remodeling; Lipid bilayer fusion; Phagosome; Cell; Biochemistry; Intracellular; Membrane","score_opus":0.041736929406220556,"score_gpt":0.36935358399298207,"score_spread":0.32761665458676154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2346811559","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00041406057,0.9972126,0.0000028871036,0.000059545746,0.00019461582,0.0005492641,0.000028700955,0.00018096814,0.0013573664],"genre_scores_gemma":[0.00013489964,0.9930543,0.00003565923,0.00013179862,0.00045796804,0.00004882929,0.000045518318,0.00007058519,0.006020466],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989069,0.000055502118,0.0002976821,0.00034278585,0.00015225691,0.00024483394],"domain_scores_gemma":[0.99916875,0.00010352199,0.00012596117,0.0003742032,0.000017349601,0.00021022614],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000085873085,0.0003208426,0.0012118475,0.00012404777,0.000046682173,0.000015761823,0.0000925358,0.00027599564,0.0006327573],"category_scores_gemma":[0.00001982044,0.000194214,0.00032161784,0.00010577502,0.00008047523,0.000033388616,0.000023029253,0.00022249471,0.00066655583],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012041402,0.000060155842,1.3232658e-7,0.005311456,0.00020276212,0.00011001588,0.000024451612,9.997626e-9,6.886078e-7,0.00009804036,0.0016904387,0.9924898],"study_design_scores_gemma":[0.0005530241,0.00009086859,0.00001531094,0.0112949265,0.00080035103,0.00021614002,0.0000025010968,0.0000012822545,0.0000033078848,0.00001025011,0.9868137,0.00019832473],"about_ca_topic_score_codex":6.147377e-7,"about_ca_topic_score_gemma":2.3411569e-7,"teacher_disagreement_score":0.9922915,"about_ca_system_score_codex":0.000055246303,"about_ca_system_score_gemma":0.00029053766,"threshold_uncertainty_score":0.8567449},"labels":[],"label_agreement":null},{"id":"W2361671990","doi":"10.1016/j.cjca.2015.07.207","title":"ENDOTHELIAL-SPECIFIC LOSS OF AUTOPHAGY PROMOTES ORGAN FIBROSIS","year":2015,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Toronto Public Health","funders":"","keywords":"Autophagy; Fibrosis; Medicine; Cardiac fibrosis; Myofibroblast; Mesenchymal stem cell; Pathology; Endothelial stem cell; Cell biology; Pulmonary fibrosis; Umbilical vein; Cancer research; Biology; In vitro; Apoptosis","score_opus":0.02611251059044569,"score_gpt":0.2550645652670825,"score_spread":0.2289520546766368,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2361671990","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98341584,0.007015588,0.0006604544,0.00092919136,0.0009539738,0.00015223474,0.00006099917,0.000008712004,0.006803008],"genre_scores_gemma":[0.99791265,0.00012786803,0.0003019236,0.00017074728,0.001255541,0.0000014067749,0.000005466816,0.000020614003,0.00020381158],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.998976,0.000103076076,0.00038917095,0.00010613896,0.00015162677,0.00027399],"domain_scores_gemma":[0.9981168,0.0000443435,0.00019563554,0.00023196854,0.000442983,0.00096825266],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032076437,0.000116836236,0.0006036797,0.00026814232,0.00003111849,0.000007040553,0.00016011376,0.00012855438,0.00012058349],"category_scores_gemma":[0.00015850537,0.00009558883,0.00022820343,0.00014375555,0.00024839645,0.00005483252,0.0000069773164,0.00019085914,0.000022943335],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040330873,0.00014056738,0.45635244,0.00038993306,0.006318491,0.020885974,0.008448241,0.0012577717,0.107432626,0.011581,0.3173149,0.06584496],"study_design_scores_gemma":[0.0070346426,0.0030592808,0.12409057,0.00021268566,0.00038083363,0.007032636,0.0005411587,0.000009497471,0.07595554,0.004590378,0.7767695,0.0003232427],"about_ca_topic_score_codex":0.0002026836,"about_ca_topic_score_gemma":0.000053770393,"teacher_disagreement_score":0.45945466,"about_ca_system_score_codex":0.00013715257,"about_ca_system_score_gemma":0.0023789522,"threshold_uncertainty_score":0.4220159},"labels":[],"label_agreement":null},{"id":"W2383223917","doi":"10.1080/15548627.2016.1164357","title":"Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia","year":2016,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":108,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; CancerCare Manitoba Foundation","keywords":"Autophagy; Biology; Programmed cell death; Cell biology; Hypoxia (environmental); Receptor tyrosine kinase; Cancer cell; Tyrosine kinase; Cancer research; Cell; Kinase; Apoptosis; Signal transduction; Chemistry; Cancer; Biochemistry","score_opus":0.020569787338169856,"score_gpt":0.27369257226523935,"score_spread":0.2531227849270695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2383223917","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9899812,0.0058709527,0.0000122557285,0.0019192463,0.00036975575,0.0007364762,0.00011244101,0.00009114321,0.0009065632],"genre_scores_gemma":[0.9930989,0.001448101,0.000088299865,0.000523333,0.0002932306,0.00011286948,0.000029783183,0.00008271574,0.0043227724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973546,0.00021892089,0.000613134,0.00069106463,0.00039405175,0.00072818954],"domain_scores_gemma":[0.9983918,0.00042610866,0.00018963024,0.00063524453,0.000065499014,0.00029172676],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004766877,0.0004377747,0.00069066935,0.00019988295,0.00009887772,0.000036461264,0.00030066157,0.00031128398,0.0006856682],"category_scores_gemma":[0.000037398535,0.0002738947,0.00011245305,0.00044552283,0.00014066976,0.00018408115,0.00011514833,0.00037546348,0.00009950328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023633384,0.0004135208,0.018514793,0.00008307766,0.000044984157,0.00007196407,0.00043188676,0.0000016967462,0.9662687,0.00012089266,0.0014648797,0.012347249],"study_design_scores_gemma":[0.0050189206,0.00023578448,0.26849264,0.00015898298,0.00006105939,0.0000018525213,0.000067211775,0.000037593712,0.722718,0.00042376234,0.0024874012,0.00029680095],"about_ca_topic_score_codex":0.0012621349,"about_ca_topic_score_gemma":0.00008485848,"teacher_disagreement_score":0.24997784,"about_ca_system_score_codex":0.000260548,"about_ca_system_score_gemma":0.0002428805,"threshold_uncertainty_score":0.99997133},"labels":[],"label_agreement":null},{"id":"W2403964217","doi":"10.1038/srep18944","title":"Mammalian autophagy is essential for hepatic and renal ketogenesis during starvation","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Japan Society for the Promotion of Science; York University; National Institutes of Health; Uehara Memorial Foundation; Takeda Science Foundation","keywords":"Ketogenesis; Autophagy; Starvation; Starvation response; Ketone bodies; Biology; Kidney; Endocrinology; Internal medicine; Gluconeogenesis; Biochemistry; Metabolism; Medicine","score_opus":0.01183651240603079,"score_gpt":0.2672981461675992,"score_spread":0.25546163376156844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2403964217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962254,0.00022466126,0.0009619565,0.0005584784,0.001406148,0.00045301174,0.000009619168,0.00006092968,0.000099765246],"genre_scores_gemma":[0.9843157,0.000015323927,0.0004967433,0.00007796547,0.00017810121,0.000049653572,0.000024316461,0.000018372615,0.014823832],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855787,0.00001490037,0.00033939976,0.0005301149,0.00031535246,0.00024237437],"domain_scores_gemma":[0.9990394,0.000023998495,0.00016781711,0.00047113936,0.0001389236,0.00015871032],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041302165,0.00011330437,0.00017266818,0.0001301211,0.00024896697,0.00006694108,0.000036528396,0.00005513679,0.00042949317],"category_scores_gemma":[0.000080563295,0.00007754153,0.00009480859,0.000145902,0.00015514047,0.00014907897,0.000024977362,0.000023965793,0.000011966326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015808687,0.00008044159,0.017519727,0.00013261204,0.00006777734,0.00034328498,0.0002649317,4.3607463e-7,0.9693891,0.00006585303,0.0037206947,0.008257093],"study_design_scores_gemma":[0.0008988196,0.000059681675,0.055939265,0.00010918355,0.00009468715,0.00022011924,0.000015833819,0.000051768264,0.9280457,0.004925116,0.009512146,0.0001276878],"about_ca_topic_score_codex":0.000008613142,"about_ca_topic_score_gemma":0.0000034490392,"teacher_disagreement_score":0.04134337,"about_ca_system_score_codex":0.00004391047,"about_ca_system_score_gemma":0.00012853432,"threshold_uncertainty_score":0.47026488},"labels":[],"label_agreement":null},{"id":"W2403972427","doi":"10.1042/bst20140281","title":"Post-translational myristoylation at the cross roads of cell death, autophagy and neurodegeneration","year":2015,"lang":"en","type":"article","venue":"Biochemical Society Transactions","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Myristoylation; Programmed cell death; Cell biology; Neurodegeneration; Cleavage (geology); Caspase; Apoptosis; Cell; Chemistry; Biology; Biochemistry; Medicine","score_opus":0.0196844109540243,"score_gpt":0.2805758941749996,"score_spread":0.26089148322097533,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2403972427","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98430365,0.0011992335,0.012745779,0.0011431533,0.00008270693,0.00019647954,0.00007026734,0.00003711096,0.00022163427],"genre_scores_gemma":[0.99722564,0.00008267069,0.0011403076,0.00041712256,0.000088341876,0.000016763624,0.00012663238,0.000012589303,0.0008899259],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992628,0.000022194701,0.00019151764,0.00017179361,0.00023969158,0.00011198457],"domain_scores_gemma":[0.9994799,0.00004465654,0.00004859996,0.0001443289,0.00015319926,0.0001293223],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009835714,0.00009873505,0.000115088624,0.000011533364,0.00015168016,0.0000118004145,0.000039811985,0.00012345971,0.00013007995],"category_scores_gemma":[0.000007650797,0.0000752166,0.00017928664,0.00009915372,0.00016579966,0.000067338806,0.000003955022,0.00011936447,0.000005797643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019398976,0.00023301232,0.0019619176,0.000042903437,0.00006936385,6.831531e-7,0.0010986185,0.0002490459,0.9948613,0.000066002496,0.0006389884,0.0005841969],"study_design_scores_gemma":[0.0017377138,0.000113014314,0.04290886,0.000007825549,0.00016389848,0.000021360884,0.00009127897,0.0046661613,0.94909954,0.0001670263,0.0009185431,0.00010478656],"about_ca_topic_score_codex":0.00002922456,"about_ca_topic_score_gemma":0.0000023886287,"teacher_disagreement_score":0.045761745,"about_ca_system_score_codex":0.00004713533,"about_ca_system_score_gemma":0.00010477382,"threshold_uncertainty_score":0.3067244},"labels":[],"label_agreement":null},{"id":"W2409736940","doi":"10.1002/cbic.201600078","title":"Small Molecule Restores Itaconate Sensitivity in <i>Salmonella enterica</i>: A Potential New Approach to Treating Bacterial Infections","year":2016,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Salmonella enterica; Context (archaeology); Biology; Intracellular; Antibiotics; Antimicrobial; Microbiology; Salmonella; Macrophage; Enzyme; Antibiotic resistance; Bacteria; Computational biology; Biochemistry; In vitro; Genetics","score_opus":0.020276197633675986,"score_gpt":0.2521445161717268,"score_spread":0.2318683185380508,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2409736940","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98921055,0.000059018657,0.0022200986,0.0005197026,0.00012548432,0.0003108594,0.000010863183,0.00009106595,0.0074523804],"genre_scores_gemma":[0.9958903,0.000021577094,0.0008236347,0.00034498898,0.00046352262,0.000031956457,0.000028714136,0.000031908065,0.0023633796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989321,0.000039531504,0.00021073919,0.0003911543,0.0001271356,0.00029933424],"domain_scores_gemma":[0.99927044,0.000036092522,0.000054154585,0.0003146036,0.000041899104,0.00028282174],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117608135,0.00018388192,0.00026820373,0.00010174824,0.000044490414,0.00001948287,0.00005947653,0.00010588405,0.00009855007],"category_scores_gemma":[0.00010251598,0.0001424212,0.00012011993,0.00019805154,0.000044340577,0.000048416925,0.00006229692,0.00009257292,0.00008429128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041384515,0.00047269423,0.0019366547,0.00002120883,0.000064384956,0.00008706823,0.00024146258,0.000002893419,0.9925958,0.00003583049,0.0010540024,0.0030741917],"study_design_scores_gemma":[0.002822627,0.00011692382,0.017310407,0.00010091364,0.000050327668,0.00008175697,0.00003738388,0.000047482015,0.9785404,0.000049188795,0.00065601437,0.00018653132],"about_ca_topic_score_codex":0.00015669847,"about_ca_topic_score_gemma":0.00001320306,"teacher_disagreement_score":0.015373753,"about_ca_system_score_codex":0.000101696605,"about_ca_system_score_gemma":0.00012144677,"threshold_uncertainty_score":0.58077675},"labels":[],"label_agreement":null},{"id":"W2410871614","doi":"10.1016/j.neo.2016.04.003","title":"RETRACTED: Role of Autophagy as a Survival Mechanism for Hypoxic Cells in Tumors","year":2016,"lang":"en","type":"article","venue":"Neoplasia","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":101,"is_retracted":true,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Gene knockdown; Hypoxia (environmental); Cancer research; Programmed cell death; Cell culture; Biology; Small hairpin RNA; Cancer cell; Cell biology; Cell; Chemistry; Apoptosis; Cancer; Oxygen; Biochemistry; Genetics","score_opus":0.008659961453352228,"score_gpt":0.2562551322039865,"score_spread":0.24759517075063425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2410871614","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99487454,0.00013480906,0.00020402377,0.00024267982,0.00023528453,0.0004716642,0.000047421014,0.000054657725,0.0037349279],"genre_scores_gemma":[0.997335,0.00005584379,0.00037149343,0.0002270135,0.00013212801,0.00004931961,0.000007159238,0.00003324334,0.0017888021],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989119,0.000032763208,0.0003000617,0.00024063574,0.00023752358,0.00027710624],"domain_scores_gemma":[0.9992261,0.00017247029,0.000103861785,0.0002862922,0.000081681654,0.00012958802],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016391762,0.00014485372,0.00035183254,0.00012855265,0.000021619513,0.0000040481737,0.00010264173,0.00016006277,0.00040512675],"category_scores_gemma":[0.00010510444,0.00010296035,0.00013049037,0.00013521679,0.000040777493,0.00006437503,0.000016914539,0.000098019555,0.000093981114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00084029755,0.00032355246,0.0013878141,0.00006449411,0.000063299136,0.000080275815,0.00024994733,5.174092e-7,0.9660631,0.020886412,0.00019977332,0.009840548],"study_design_scores_gemma":[0.003968619,0.0005843605,0.020838255,0.00017915718,0.0000438396,0.000025615844,0.00013535174,0.00007882231,0.94817924,0.024485221,0.0013504929,0.00013103009],"about_ca_topic_score_codex":0.000048921658,"about_ca_topic_score_gemma":0.00001734398,"teacher_disagreement_score":0.019450441,"about_ca_system_score_codex":0.0000515093,"about_ca_system_score_gemma":0.00018932167,"threshold_uncertainty_score":0.44358537},"labels":[],"label_agreement":null},{"id":"W2412702464","doi":"10.1080/15384101.2015.1071136","title":"DENND3: a signaling/trafficking interface in autophagy","year":2015,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Autophagy; Biology; Cell biology; Cytosol; BAG3; Signal transduction; Apoptosis; Biochemistry; Enzyme","score_opus":0.02087177410779459,"score_gpt":0.28421298128391476,"score_spread":0.2633412071761202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2412702464","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.80569375,0.015697436,0.0001828178,0.13791513,0.001617254,0.0013227075,0.000041613934,0.0005323785,0.036996905],"genre_scores_gemma":[0.60825545,0.00007353165,0.0002204665,0.37639925,0.003098243,0.000046338682,0.00020977124,0.00015996912,0.011536986],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99809766,0.000082341,0.00038785738,0.00049820193,0.00041753068,0.0005163974],"domain_scores_gemma":[0.99900717,0.00007287368,0.00014571511,0.00054538134,0.00007841715,0.00015043018],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019715479,0.0003606474,0.00060403143,0.00023896404,0.000031887525,0.00003434744,0.00025475136,0.0007223731,0.0007872815],"category_scores_gemma":[0.000027769953,0.00034075376,0.00019001047,0.00019396032,0.00007006484,0.000057108744,0.0000648659,0.0016408567,0.0006743601],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009890877,0.00018867508,0.00007756243,0.0004164098,0.00007761221,0.0047251666,0.00084789935,0.00016476425,0.0030657141,0.0000021842243,0.98889923,0.0014358809],"study_design_scores_gemma":[0.0029983036,0.00025593242,0.00016585318,0.0006694091,0.00019118411,0.00007493683,0.00011823294,0.0008485067,0.03929231,0.0005434887,0.95425534,0.00058651157],"about_ca_topic_score_codex":0.000047492165,"about_ca_topic_score_gemma":0.000002678218,"teacher_disagreement_score":0.23848411,"about_ca_system_score_codex":0.00023236581,"about_ca_system_score_gemma":0.0003280074,"threshold_uncertainty_score":0.99990445},"labels":[],"label_agreement":null},{"id":"W2413860537","doi":"10.3748/wjg.v21.i47.13225","title":"Hepatitis B and C virus-induced hepatitis: Apoptosis, autophagy, and unfolded protein response","year":2015,"lang":"en","type":"article","venue":"World Journal of Gastroenterology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Manitoba Medical Service Foundation","keywords":"Apoptosis; Autophagy; Unfolded protein response; Hepatitis B virus; Western blot; Hepatitis C virus; Virology; Antibody; Biology; Molecular biology; Immunology; Virus","score_opus":0.018241947510223292,"score_gpt":0.2724744623869071,"score_spread":0.2542325148766838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2413860537","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946637,0.0009891506,0.000103338934,0.0036992012,0.00021636397,0.00024157405,0.000007751523,0.000020043091,0.000058885806],"genre_scores_gemma":[0.9960648,0.00038135922,0.0011401693,0.0019385191,0.0001981126,0.000010859394,0.0000022904321,0.00002319598,0.00024069496],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99842423,0.00035316029,0.0004932678,0.0001810033,0.00024851243,0.00029980138],"domain_scores_gemma":[0.9987489,0.000052479052,0.00032389956,0.00017660044,0.00018419357,0.00051395036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006636204,0.00018255,0.0005421727,0.00036144085,0.00005000043,0.000023676263,0.00009193066,0.00006734769,0.00006576144],"category_scores_gemma":[0.00014768503,0.00015309999,0.00008612434,0.00010679177,0.00015425193,0.00014622729,0.00005561434,0.00031133322,0.000004921237],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.065823674,0.0006177975,0.7609827,0.00007497131,0.0007816407,0.001476614,0.00096419704,0.0000024029941,0.15822056,0.00018661704,0.0046528354,0.006215994],"study_design_scores_gemma":[0.015828216,0.016566755,0.92731667,0.00038611854,0.00032541712,0.0035452833,0.000113768445,0.00008984604,0.030852884,0.001379236,0.003414047,0.00018175058],"about_ca_topic_score_codex":0.00009421261,"about_ca_topic_score_gemma":0.00021828385,"teacher_disagreement_score":0.16633397,"about_ca_system_score_codex":0.000072540824,"about_ca_system_score_gemma":0.00013637963,"threshold_uncertainty_score":0.62432367},"labels":[],"label_agreement":null},{"id":"W2414187979","doi":"10.1016/j.taap.2016.06.006","title":"Lysosomotropic cationic drugs induce cytostatic and cytotoxic effects: Role of liposolubility and autophagic flux and antagonism by cholesterol ablation","year":2016,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Pharmacology; Cytotoxicity; Cytostasis; Phospholipidosis; Chloroquine; Chemistry; Cell growth; Biology; In vitro; Biochemistry; Immunology","score_opus":0.005264603470628354,"score_gpt":0.26318990205719445,"score_spread":0.2579252985865661,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2414187979","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949482,0.0027780524,0.00005233777,0.0010089113,0.00008166788,0.0008656508,0.000024957626,0.00004228605,0.00019790957],"genre_scores_gemma":[0.99702185,0.0011201437,0.000070421345,0.0014176624,0.00006813363,0.000134586,0.000017566925,0.000017562808,0.00013208188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987939,0.00013631712,0.00029204824,0.00042883525,0.00007963364,0.00026925263],"domain_scores_gemma":[0.9990896,0.00040517154,0.0001441442,0.00013371847,0.000027205524,0.00020015106],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018230488,0.00020788802,0.00045288127,0.00009416266,0.00012929029,0.000008067167,0.00004883806,0.00024346638,0.00012659417],"category_scores_gemma":[0.000014333607,0.0001610483,0.000021164826,0.000070164446,0.0006807471,0.000082050414,0.00006813838,0.00016969553,0.0000048926586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043061498,0.00020694554,0.0057730847,0.0001926593,0.0001558252,0.0000041921894,0.0004923799,1.9052908e-7,0.9518668,0.0008043551,0.000068986905,0.04000397],"study_design_scores_gemma":[0.008252912,0.0007666315,0.17706993,0.000026505617,0.0003674416,0.00007907529,0.00006703225,0.00010513734,0.80827546,0.0044561843,0.00036004483,0.000173623],"about_ca_topic_score_codex":0.0000062224617,"about_ca_topic_score_gemma":0.0000012209681,"teacher_disagreement_score":0.17129685,"about_ca_system_score_codex":0.00003294857,"about_ca_system_score_gemma":0.000065090455,"threshold_uncertainty_score":0.65673596},"labels":[],"label_agreement":null},{"id":"W2414205763","doi":"10.1038/srep27215","title":"Foci of cyclin A2 interact with actin and RhoA in mitosis","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Fondation ARC pour la Recherche sur le Cancer; Agence Nationale de la Recherche; Institute of Genetics; Fondation pour la Recherche Médicale; University of Oxford","keywords":"RHOA; Cell biology; Cyclin A; Mitosis; Cyclin A2; Cyclin B; Cyclin D; Mitotic exit; Biology; Cyclin E; Cell cycle; Cyclin; Chemistry; Cell; Anaphase; Genetics; Signal transduction","score_opus":0.009541413462149118,"score_gpt":0.26859652777962195,"score_spread":0.25905511431747286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2414205763","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99734557,0.00020576412,0.000033825425,0.0003976832,0.00057491293,0.00017753479,0.0000012967967,0.00001589155,0.0012474973],"genre_scores_gemma":[0.99669224,0.000017072613,0.00018580648,0.000035454806,0.000026185444,0.000008639164,0.0000036037502,0.000008591676,0.0030223879],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989963,0.000017883816,0.00028277436,0.00033263012,0.00023137082,0.00013902066],"domain_scores_gemma":[0.99921805,0.00004384007,0.00016699864,0.00041883186,0.000060317772,0.00009194578],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039001778,0.00007612008,0.00018362592,0.00013788216,0.00003013972,0.000017087272,0.00003186149,0.000033612065,0.0002072737],"category_scores_gemma":[0.000092587,0.000041773543,0.000038844508,0.00019121775,0.00020692147,0.00010064417,0.00002081272,0.000045028068,0.0000051893603],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003661274,0.0003558229,0.4776466,0.000077287164,0.00007577589,0.0015816567,0.0008178354,4.4680996e-7,0.4709253,0.000032646632,0.0033943185,0.044726186],"study_design_scores_gemma":[0.0015523355,0.00022344204,0.29364973,0.00095418404,0.000059855647,0.0005575976,0.00020140722,0.000009787876,0.68783146,0.0025831244,0.012214862,0.00016221593],"about_ca_topic_score_codex":0.000024297264,"about_ca_topic_score_gemma":0.000021161783,"teacher_disagreement_score":0.21690616,"about_ca_system_score_codex":0.000021045724,"about_ca_system_score_gemma":0.00009680736,"threshold_uncertainty_score":0.22695017},"labels":[],"label_agreement":null},{"id":"W2414235983","doi":"10.1371/journal.ppat.1005690","title":"Leishmania major Promastigotes Evade LC3-Associated Phagocytosis through the Action of GP63","year":2016,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Universitaire Stichting; McMaster University","keywords":"Phagosome; Phagocytosis; Cell biology; NADPH oxidase; Phagolysosome; Leishmania; Internalization; Autophagy; Biology; Microbiology; Intracellular parasite; Chemistry; Reactive oxygen species; Intracellular; Biochemistry; Apoptosis; Parasite hosting; Cell","score_opus":0.047699403833885046,"score_gpt":0.2921388037112096,"score_spread":0.24443939987732455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2414235983","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99553466,0.00046599744,0.00016715756,0.0018170872,0.00011349488,0.0005079526,0.00013447253,0.00011917459,0.0011399821],"genre_scores_gemma":[0.99790233,0.00020296671,0.00016409026,0.0004134576,0.00019138644,0.00006687978,0.000018808687,0.00003589661,0.0010042074],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987776,0.000090562404,0.00027052852,0.00023628958,0.00036045993,0.00026453685],"domain_scores_gemma":[0.99903494,0.00016774457,0.00018393573,0.00039610092,0.00013925783,0.00007800424],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000109964574,0.00016602883,0.000296324,0.000039790284,0.00010904885,0.0000078138155,0.00012644361,0.00011001971,0.0005874965],"category_scores_gemma":[0.00023630298,0.00008648887,0.00017451751,0.00018880378,0.00010175091,0.0001119996,0.000030452602,0.00009699532,0.000108192515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020953895,0.0006425316,0.017856017,0.000053626864,0.0005503709,0.00002519744,0.0005997994,3.0694557e-7,0.9750118,0.00024792986,0.00061174773,0.004191108],"study_design_scores_gemma":[0.00239966,0.0004047997,0.12536594,0.00031385286,0.0006761858,0.000013998669,0.00020169618,0.000029874378,0.86803746,0.0012131808,0.0011740548,0.00016928707],"about_ca_topic_score_codex":0.000021825475,"about_ca_topic_score_gemma":0.000008456106,"teacher_disagreement_score":0.107509926,"about_ca_system_score_codex":0.00008505299,"about_ca_system_score_gemma":0.00010219227,"threshold_uncertainty_score":0.64326745},"labels":[],"label_agreement":null},{"id":"W2420981549","doi":"10.1080/15548627.2016.1191722","title":"Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells","year":2016,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Public Health Agency of Canada","keywords":"Autophagy; Unfolded protein response; Proteasome; Withaferin A; Endoplasmic reticulum; Biology; Cell biology; Endoplasmic-reticulum-associated protein degradation; Ubiquitin; Apoptosis; Mitophagy; Protein degradation; Proteostasis; Withania somnifera; Biochemistry; Medicine","score_opus":0.008497900262956543,"score_gpt":0.2591517427735046,"score_spread":0.25065384251054806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2420981549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966367,0.0015946692,0.000020158248,0.00018290996,0.00022520089,0.00089520484,0.0001308987,0.00008884763,0.00022539914],"genre_scores_gemma":[0.9985626,0.00022315669,0.00001441322,0.00018242809,0.00011179276,0.00018768276,0.000008646312,0.000043542386,0.0006657392],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99808544,0.00016297278,0.0005479185,0.00043051364,0.0003882753,0.00038485083],"domain_scores_gemma":[0.99878377,0.00020184056,0.00032379318,0.00044905746,0.000092894436,0.00014864483],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016985554,0.00029000893,0.00055783265,0.000123246,0.000116532174,0.000017512439,0.00015261702,0.00019218112,0.00017275158],"category_scores_gemma":[0.000056264224,0.00017421668,0.00011751317,0.00028457228,0.00019455982,0.000118163385,0.00006808016,0.00016576749,0.0000091299935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007168506,0.00017286517,0.0013482795,0.0003859342,0.00009925067,0.00002039574,0.0003849711,0.000004159151,0.9918091,0.0003781428,0.00006089168,0.0052642906],"study_design_scores_gemma":[0.002157724,0.00020896121,0.008222805,0.0019812323,0.00012170344,0.000006426178,0.00019826413,0.000080080004,0.9866294,0.00012740344,0.000064370404,0.00020160571],"about_ca_topic_score_codex":0.0006669498,"about_ca_topic_score_gemma":0.000039416303,"teacher_disagreement_score":0.0068745255,"about_ca_system_score_codex":0.00019556683,"about_ca_system_score_gemma":0.00011953226,"threshold_uncertainty_score":0.710435},"labels":[],"label_agreement":null},{"id":"W2428011008","doi":"10.1080/15548627.2016.1191724","title":"Autophagy proteins are not universally required for phagosome maturation","year":2016,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Phagosome; Cell biology; Phagocytosis; Autophagy; Biology; Internalization; Phagolysosome; Lysosome; Autophagosome; Cell; Biochemistry; Apoptosis","score_opus":0.024608233133906015,"score_gpt":0.28214679112788726,"score_spread":0.25753855799398123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2428011008","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9619553,0.0010574204,0.021679502,0.007617261,0.00087862805,0.0030684036,0.00022249973,0.0009018978,0.0026190593],"genre_scores_gemma":[0.97921705,0.00007009645,0.0017889877,0.0016563796,0.00059620856,0.00023840698,0.00005059426,0.00007678562,0.016305517],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99817455,0.00005524465,0.00038618819,0.0005299228,0.0003546606,0.00049945305],"domain_scores_gemma":[0.9985124,0.00014239154,0.00023935127,0.00060391705,0.00024114593,0.00026078417],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018624251,0.00029844986,0.00044653146,0.00016459079,0.00017278815,0.000029840154,0.00019733368,0.00021702844,0.0006211151],"category_scores_gemma":[0.0001765223,0.00020928826,0.00027080034,0.00019220731,0.00012985506,0.0003737812,0.000040681356,0.00010027824,0.00030168743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004314695,0.00070058083,0.0004907442,0.0002734716,0.000572764,0.0003997509,0.00032385642,0.0000032435291,0.8959309,0.02676912,0.0052674627,0.06495341],"study_design_scores_gemma":[0.011201838,0.00087209145,0.102149494,0.0003883532,0.00023351933,0.000082714396,0.000059801034,0.0003309841,0.8410167,0.004599528,0.038557135,0.00050782366],"about_ca_topic_score_codex":0.000013330636,"about_ca_topic_score_gemma":0.0000073654232,"teacher_disagreement_score":0.101658754,"about_ca_system_score_codex":0.00019991046,"about_ca_system_score_gemma":0.000324756,"threshold_uncertainty_score":0.85345274},"labels":[],"label_agreement":null},{"id":"W2430251295","doi":"10.1038/cdd.2016.49","title":"Chewing the fat about death with the neighbours","year":2016,"lang":"en","type":"editorial","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Programmed cell death; Necroptosis; Apoptosis; Autophagy; Cell biology; Biology; FADD; Cell; Caspase; Genetics","score_opus":0.008151438858047455,"score_gpt":0.24649207458853284,"score_spread":0.2383406357304854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2430251295","genre_codex":"editorial","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4545018,0.019542057,0.0036928433,0.0019621558,0.501626,0.0022610498,0.00022730588,0.00023995557,0.015946837],"genre_scores_gemma":[0.5860822,0.0023976683,0.000011284624,0.00027701078,0.40232602,0.00007429283,0.0004482931,0.000058252666,0.008324993],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.998636,0.00006718901,0.00017587419,0.0003248203,0.000516096,0.00028002035],"domain_scores_gemma":[0.99875695,0.00036494498,0.00019769471,0.00043450316,0.00012156054,0.0001243777],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000113039365,0.00030268834,0.00030497342,0.00004858281,0.0003110193,0.000108961205,0.00015501055,0.00032227667,0.00012775674],"category_scores_gemma":[0.00004050234,0.00011782997,0.00011486415,0.000053853135,0.000068758854,0.000062972045,0.00003761903,0.0004015732,0.000021546713],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010130497,0.00020722902,0.006385984,0.00039824678,0.0005475904,0.000031157808,0.0009777421,6.324173e-7,0.00075717986,0.001077404,0.9812765,0.007327291],"study_design_scores_gemma":[0.0064359223,0.0005425265,0.09798534,0.0007572809,0.0024013391,0.0000073490255,0.00015923948,0.00010888981,0.003011862,0.0015328547,0.8864395,0.0006179146],"about_ca_topic_score_codex":0.00002506922,"about_ca_topic_score_gemma":0.0000065581935,"teacher_disagreement_score":0.1315804,"about_ca_system_score_codex":0.000051789888,"about_ca_system_score_gemma":0.00013448534,"threshold_uncertainty_score":0.48049667},"labels":[],"label_agreement":null},{"id":"W2443613404","doi":"10.1016/j.ccell.2016.05.002","title":"Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells","year":2016,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":216,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer; Hospital for Sick Children; Ontario College of Art and Design; Toronto Western Hospital; SickKids Foundation; University of Toronto","funders":"National Institute of General Medical Sciences; Genome Canada; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; European Research Council; National Institutes of Health; Ontario Institute for Cancer Research","keywords":"Autophagy; Neurochemical; Neural stem cell; Cell biology; Stem cell; PI3K/AKT/mTOR pathway; Biology; Dopamine; Cell growth; Dopaminergic; Vacuole; Neuroscience; Cancer research; Signal transduction; Chemistry; Apoptosis; Cytoplasm; Biochemistry","score_opus":0.010756534481678444,"score_gpt":0.25056841952398573,"score_spread":0.2398118850423073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2443613404","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99545103,0.0031085052,0.00021691331,0.00011282434,0.00019008944,0.0002841102,0.00007231628,0.000027654549,0.0005365265],"genre_scores_gemma":[0.99438554,0.0011036883,0.000047379755,0.000061004735,0.00017320068,0.000027695049,0.0000054530747,0.000019212644,0.0041768225],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992158,0.000034959794,0.0002712274,0.00017830518,0.00017181746,0.00012793414],"domain_scores_gemma":[0.99938434,0.000045174856,0.00015420861,0.00017533766,0.00014623038,0.00009473148],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000091059606,0.000113715985,0.00026257776,0.000044575885,0.000022249476,0.000003513854,0.00003371218,0.00006524462,0.00088550046],"category_scores_gemma":[0.000004038603,0.00007749,0.00005380133,0.00007755691,0.0001042459,0.0000926858,0.000016893344,0.00003506974,0.000009857074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005084616,0.00011936732,0.0027284452,0.0002958862,0.000039777853,0.0000029291798,0.00021414954,0.0000013328251,0.98307705,0.00006487434,0.00058222807,0.012365524],"study_design_scores_gemma":[0.0022943171,0.00048327853,0.0013836911,0.00021286195,0.000055335142,0.0000015762657,0.00010012728,0.00001783801,0.9937036,0.00003889997,0.0016259855,0.00008250282],"about_ca_topic_score_codex":0.000025133771,"about_ca_topic_score_gemma":0.000011428256,"teacher_disagreement_score":0.012283022,"about_ca_system_score_codex":0.00005502593,"about_ca_system_score_gemma":0.00013161925,"threshold_uncertainty_score":0.9695609},"labels":[],"label_agreement":null},{"id":"W2464216456","doi":"10.7555/jbr.30.20150137","title":"Complex role of autophagy in regulation of hepatic lipid andlipoprotein metabolism","year":2016,"lang":"en","type":"article","venue":"Journal of Biomedical Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Autophagy; Very low-density lipoprotein; Lipid metabolism; Cell biology; Lipid droplet; Biogenesis; Apolipoprotein B; Lipoprotein; Chemistry; Biochemistry; Biology; Cholesterol; Gene","score_opus":0.05208958528348802,"score_gpt":0.38907255957114856,"score_spread":0.33698297428766055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2464216456","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99551004,0.0014414656,0.00027989887,0.0021759884,0.000065166496,0.00020988272,0.000009263494,0.0000029906355,0.00030530454],"genre_scores_gemma":[0.99830675,0.000393726,0.0007280196,0.000030383972,0.00033219624,0.000003517599,0.000002439727,0.000011164953,0.0001918046],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99627966,0.00037209387,0.0010083509,0.00011705801,0.0019539404,0.00026889506],"domain_scores_gemma":[0.99797004,0.00045886743,0.0003527134,0.00025402356,0.0006616473,0.00030272565],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0034915823,0.0000822187,0.0005756505,0.00084793335,0.000021224077,0.000004135771,0.00021750017,0.00012299044,0.0015212905],"category_scores_gemma":[0.0015176359,0.000045627294,0.00016411739,0.00064870634,0.0005289818,0.00009311362,0.000051853338,0.00029143132,0.000010637641],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012292775,0.0006687409,0.0021740033,0.0000980612,0.00009305681,0.00004537835,0.00018311167,2.2957691e-7,0.8562743,0.0006132237,0.00065772387,0.13796291],"study_design_scores_gemma":[0.0059219934,0.0015593843,0.6218251,0.0009348903,0.000038234935,0.000059621096,0.00013693751,0.00034013763,0.34822482,0.010252743,0.01063884,0.00006727106],"about_ca_topic_score_codex":0.000057335852,"about_ca_topic_score_gemma":0.0000026112157,"teacher_disagreement_score":0.61965114,"about_ca_system_score_codex":0.00007980462,"about_ca_system_score_gemma":0.00051817956,"threshold_uncertainty_score":0.99939144},"labels":[],"label_agreement":null},{"id":"W2466888597","doi":"10.1038/nrrheum.2016.92","title":"Autophagy: controlling cell fate in rheumatic diseases","year":2016,"lang":"en","type":"review","venue":"Nature Reviews Rheumatology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":158,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Krembil Foundation; Toronto Western Hospital; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Medicine; Programmed cell death; Cell biology; Rheumatoid arthritis; Cancer research; Immunology; Apoptosis; Biology","score_opus":0.021203108873961603,"score_gpt":0.3591057296754487,"score_spread":0.3379026208014871,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2466888597","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000025660169,0.9937659,0.00006448674,0.00010545112,0.0009630664,0.004062989,0.000097866,0.00015740519,0.0007571906],"genre_scores_gemma":[0.00016673184,0.9971621,0.00011121416,0.0004243036,0.0001078535,0.00090269273,0.00026557155,0.00017024849,0.00068927335],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9939938,0.0010623913,0.0026369242,0.0010644043,0.00034900644,0.00089345674],"domain_scores_gemma":[0.9957202,0.0009785263,0.001457096,0.0013347405,0.000084990745,0.00042444313],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0006406517,0.0011614552,0.010314404,0.00070221274,0.00008099894,0.000027398699,0.0005739213,0.0020969952,0.0009357283],"category_scores_gemma":[0.0006511782,0.0006850825,0.0020822268,0.00063629233,0.00016834863,0.00010325811,0.00010775696,0.0020750246,0.0020511248],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035395817,0.00024852538,0.00005565698,0.087723404,0.0002751007,0.00029441577,0.000017367869,3.283232e-8,3.0393014e-7,0.0007217949,0.0023275872,0.9083004],"study_design_scores_gemma":[0.0020300092,0.000059020458,0.000016661343,0.12770747,0.0013090621,0.00057194754,0.000002192062,0.0000074410445,0.0000013610295,0.0002705681,0.867492,0.00053223956],"about_ca_topic_score_codex":0.000005888464,"about_ca_topic_score_gemma":0.0000021386836,"teacher_disagreement_score":0.9077682,"about_ca_system_score_codex":0.0003026973,"about_ca_system_score_gemma":0.00083960226,"threshold_uncertainty_score":0.9999775},"labels":[],"label_agreement":null},{"id":"W2468556937","doi":"10.1038/srep28423","title":"Trehalose, sucrose and raffinose are novel activators of autophagy in human keratinocytes through an mTOR-independent pathway","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":110,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"Peking Union Medical College; Fundamental Research Funds for the Central Universities; Natural Science Foundation of Jiangsu Province; Government of Jiangsu Province; Ministry of Education of the People's Republic of China; National Natural Science Foundation of China","keywords":"Raffinose; Trehalose; Autophagy; PI3K/AKT/mTOR pathway; Cell biology; Sucrose; Chemistry; Biochemistry; Biology; Signal transduction; Apoptosis","score_opus":0.02403538361221876,"score_gpt":0.29488502221434315,"score_spread":0.2708496386021244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2468556937","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99753445,0.00036733845,0.000045801098,0.00008922897,0.0009452681,0.00042182306,0.00001573572,0.000063467385,0.000516874],"genre_scores_gemma":[0.99767065,0.00001533316,0.00020167464,0.000048914975,0.00007870423,0.000023332192,0.000026123826,0.000025315678,0.0019099548],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997642,0.000046829824,0.0006432578,0.0007988641,0.0005444561,0.00032460722],"domain_scores_gemma":[0.9982465,0.00004295388,0.0004357655,0.0009299508,0.00014039494,0.00020446075],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006495682,0.00020873868,0.0004186583,0.0001919288,0.00016681037,0.00006393152,0.00009513123,0.00012139311,0.00023940614],"category_scores_gemma":[0.000119594566,0.0001405316,0.00009765607,0.00028982418,0.00041141757,0.00051391404,0.000062008905,0.00010402433,0.0000034885036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000079613055,0.0008876074,0.07833849,0.00005413739,0.000037562895,0.0010174758,0.0009432249,0.0000016693095,0.9143605,0.00054959446,0.00023961364,0.003490475],"study_design_scores_gemma":[0.0016401655,0.00016143524,0.24648035,0.000248513,0.000022931006,0.00019027144,0.00021532072,0.000008338969,0.7466238,0.0023375193,0.0018962902,0.0001750847],"about_ca_topic_score_codex":0.000074558586,"about_ca_topic_score_gemma":0.000057275472,"teacher_disagreement_score":0.16814186,"about_ca_system_score_codex":0.00007738048,"about_ca_system_score_gemma":0.00023341675,"threshold_uncertainty_score":0.57307124},"labels":[],"label_agreement":null},{"id":"W2469928790","doi":"10.1016/j.cell.2016.05.039","title":"Parkinson’s Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation","year":2016,"lang":"en","type":"article","venue":"Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":578,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; McGill University; Montreal Neurological Institute and Hospital; McGill University Health Centre; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Parkin; PINK1; Mitophagy; Biology; Autophagy; Cell biology; Antigen presentation; Mitochondrion; Immune system; Antigen; Cross-presentation; Immunology; Disease; Parkinson's disease; Genetics; Apoptosis; T cell; Pathology; Medicine","score_opus":0.010843106884670136,"score_gpt":0.2530661214426078,"score_spread":0.24222301455793768,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2469928790","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930827,0.0021423013,0.00028427644,0.0008781799,0.0002700633,0.00088908814,0.000022529774,0.000101016034,0.0023298496],"genre_scores_gemma":[0.9920369,0.0006294045,0.00019910985,0.00014199098,0.000293337,0.00007981545,0.00002624018,0.000025525991,0.006567681],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990507,0.00005516954,0.00019026705,0.0003238969,0.00018615637,0.00019386086],"domain_scores_gemma":[0.9992439,0.000039686212,0.00007600178,0.00033699578,0.00004006762,0.00026334962],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000050149276,0.00012623965,0.0001584418,0.000049189763,0.000062624385,0.000015987142,0.000060550083,0.000074733485,0.00044215066],"category_scores_gemma":[0.000042185842,0.00008418101,0.00006915781,0.000068108006,0.00008764196,0.00009827667,0.000027919561,0.00006236423,0.000102457096],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003297897,0.00088618154,0.11419899,0.0002732512,0.00028824538,0.00054011535,0.0009511567,0.0000027111319,0.8382284,0.00026028833,0.015587127,0.02548563],"study_design_scores_gemma":[0.008973656,0.0002589824,0.63827777,0.00029788897,0.00023735513,0.000013614659,0.00004018525,0.00013557832,0.25680244,0.0028362572,0.09179801,0.0003282717],"about_ca_topic_score_codex":0.000014895415,"about_ca_topic_score_gemma":9.738701e-7,"teacher_disagreement_score":0.58142596,"about_ca_system_score_codex":0.000022285498,"about_ca_system_score_gemma":0.00006822615,"threshold_uncertainty_score":0.48412395},"labels":[],"label_agreement":null},{"id":"W2473094839","doi":"10.1039/c6mb00069j","title":"Autophagy-related intrinsically disordered proteins in intra-nuclear compartments","year":2016,"lang":"en","type":"article","venue":"Molecular BioSystems","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Hospital Edmonton; University of Alberta","funders":"","keywords":"Autophagy; Cell biology; Biology; Programmed cell death; Computational biology; Nuclear protein; Intrinsically disordered proteins; Transcription factor; Genetics; Biophysics; Gene; Apoptosis","score_opus":0.006129941851930765,"score_gpt":0.23773160902111223,"score_spread":0.23160166716918146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2473094839","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941408,0.0006626111,0.0002456732,0.0014021656,0.00018894495,0.0012883272,0.0000144027745,0.00017966895,0.0018773844],"genre_scores_gemma":[0.99886745,0.000034330416,0.000121072495,0.00041114696,0.000043649557,0.00006790811,0.00001630024,0.000054046784,0.00038407606],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99831074,0.00013220754,0.00046819172,0.00038579665,0.0003324823,0.00037058358],"domain_scores_gemma":[0.9991142,0.000019612813,0.00010413607,0.00049833464,0.000053369615,0.00021035082],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015877678,0.00022454365,0.00041687264,0.00016509625,0.00004238757,0.00002048344,0.00015455404,0.00016337467,0.000312529],"category_scores_gemma":[0.00005618483,0.00015196082,0.00014205788,0.00029259222,0.00008257317,0.00006034444,0.000049205046,0.00013088335,0.0004792746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036743973,0.000805218,0.0044086166,0.00011512979,0.00030484376,0.0011323096,0.00024876505,0.0000016459625,0.9784172,0.005237078,0.0003022022,0.008659545],"study_design_scores_gemma":[0.046778664,0.002880229,0.14894645,0.004260993,0.00031947624,0.00041789172,0.00028017434,0.0010439145,0.7464253,0.0038506854,0.042973313,0.0018229135],"about_ca_topic_score_codex":0.000038179238,"about_ca_topic_score_gemma":0.000006251097,"teacher_disagreement_score":0.23199192,"about_ca_system_score_codex":0.00012998373,"about_ca_system_score_gemma":0.000076298464,"threshold_uncertainty_score":0.61967826},"labels":[],"label_agreement":null},{"id":"W2480603688","doi":"10.15171/ijbsm.2016.01","title":"Autophagy, a Possible Future Approach for Tuberculosis Treatment","year":2016,"lang":"en","type":"article","venue":"International journal of basic science in medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"","keywords":"Autophagy; Tuberculosis; Medicine; Virology; Computational biology; Biology; Genetics; Pathology","score_opus":0.026283520879701427,"score_gpt":0.3536867436417676,"score_spread":0.3274032227620662,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2480603688","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.959717,0.0010918695,0.006865629,0.027598727,0.0021302176,0.00030633653,0.000010197312,0.000013151923,0.0022668971],"genre_scores_gemma":[0.9915403,0.0007090569,0.0037699924,0.00087775406,0.002482755,0.000016606826,0.0000026339217,0.0000096352205,0.0005912518],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9981576,0.000018139044,0.00046519845,0.00020502195,0.00094058405,0.00021345969],"domain_scores_gemma":[0.99864143,0.00013124796,0.00022089097,0.00015867286,0.00064395694,0.00020377769],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008553399,0.00012261566,0.00031155616,0.0006452871,0.000042286287,0.000014471398,0.0004049105,0.00004412016,0.0002938519],"category_scores_gemma":[0.00032046455,0.0000593079,0.00012564701,0.00032344143,0.0004180881,0.0002909574,0.000019329778,0.0000753041,0.000004628143],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034296103,0.0019719999,0.043338515,0.000039335875,0.0004974718,0.00064334,0.0024740775,0.00005467415,0.18523413,0.0033537394,0.0045764176,0.75438666],"study_design_scores_gemma":[0.08798108,0.015120442,0.6102418,0.0040013725,0.0006741483,0.006405146,0.004674529,0.0053019216,0.2037297,0.010370008,0.050718408,0.0007814795],"about_ca_topic_score_codex":0.000010530001,"about_ca_topic_score_gemma":7.823718e-7,"teacher_disagreement_score":0.7536052,"about_ca_system_score_codex":0.00053595135,"about_ca_system_score_gemma":0.0005377579,"threshold_uncertainty_score":0.3217472},"labels":[],"label_agreement":null},{"id":"W2493702704","doi":"10.1042/bcj20160385","title":"Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy","year":2016,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":136,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saint John Regional Hospital; Dalhousie University","funders":"Dalhousie University; Fondation de la recherche en santé du Nouveau-Brunswick","keywords":"TFEB; Autophagy; Cell biology; Proteotoxicity; Programmed cell death; Biology; Proteostasis; Cathepsin D; Cathepsin B; Cardiotoxicity; Chemistry; Cancer research; Biochemistry; Apoptosis; Protein aggregation","score_opus":0.01115654824412344,"score_gpt":0.2709673227004964,"score_spread":0.25981077445637296,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2493702704","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925456,0.0031328523,0.0031485506,0.0006765012,0.00016797274,0.00015309887,0.00003999424,0.000062817366,0.00007260839],"genre_scores_gemma":[0.998447,0.00028079696,0.0005182063,0.00016366947,0.00044541812,0.000005075753,0.000007857031,0.00002403219,0.00010792434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99858785,0.00009656196,0.00035329052,0.00029302092,0.00033031384,0.00033894784],"domain_scores_gemma":[0.99905616,0.000089057394,0.000111598936,0.00020012422,0.00006869363,0.00047436793],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022527805,0.00019695457,0.00031200537,0.00005275979,0.00015086438,0.00004968472,0.00008596407,0.00016632209,0.00028678044],"category_scores_gemma":[0.000119689954,0.00011603245,0.00019380769,0.000059383317,0.00015202114,0.00019980822,0.000028909684,0.00025505715,0.000005683598],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003868624,0.0000962425,0.0032810806,0.00003801368,0.000048856185,0.000032827153,0.00015038301,4.5798913e-8,0.97802234,0.0000022031777,0.0015266145,0.016414555],"study_design_scores_gemma":[0.002587106,0.00012497172,0.013646909,0.00033318996,0.00006399368,0.00034445032,0.000053597225,0.000022475171,0.9809327,0.0002004366,0.0015306595,0.00015948799],"about_ca_topic_score_codex":0.0000024760648,"about_ca_topic_score_gemma":3.663793e-8,"teacher_disagreement_score":0.016255068,"about_ca_system_score_codex":0.00012761804,"about_ca_system_score_gemma":0.000063001484,"threshold_uncertainty_score":0.47316658},"labels":[],"label_agreement":null},{"id":"W2497455641","doi":"10.1158/1538-7445.am2016-3668","title":"Abstract 3668: Investigating a tumor suppressor role for Parkinson's susceptibility gene LRRK2 in lung cancer","year":2016,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"LRRK2; Autophagy; Lung cancer; Cancer research; Gene knockdown; Biology; Cancer; Tumor suppressor gene; Medicine; Pathology; Gene; Carcinogenesis; Genetics; Mutation","score_opus":0.07226231417647683,"score_gpt":0.4272144947871791,"score_spread":0.3549521806107023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2497455641","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9899414,0.005216122,0.000028952441,0.0026823212,0.00009790479,0.0014117482,0.0002473803,0.00004871858,0.00032545504],"genre_scores_gemma":[0.99508566,0.00048667568,0.0002432435,0.0004185321,0.00052850496,0.0022484623,0.000010989697,0.000052922285,0.0009249928],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975964,0.00009468534,0.00032323127,0.0005725054,0.00057442265,0.00083876454],"domain_scores_gemma":[0.9983538,0.00037147952,0.00006948161,0.0004986991,0.000334469,0.00037208342],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011373112,0.00017275922,0.00032955143,0.00018285052,0.00014381716,0.000028745008,0.0002434984,0.0001002001,0.0014183071],"category_scores_gemma":[0.0005093726,0.00012124187,0.00011025533,0.00031335079,0.00030899857,0.00014548919,0.00007631754,0.0003491578,0.000014774994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008237335,0.00014836091,0.12963675,0.00046341994,0.00007377928,0.000036938334,0.00046418599,0.000033209973,0.85303783,0.000075519274,0.0052972413,0.009909051],"study_design_scores_gemma":[0.004739658,0.00014777179,0.2509407,0.0010886672,0.000031461565,0.0000025597637,0.00013858484,0.0012252354,0.7330183,0.0022450355,0.006170476,0.00025154377],"about_ca_topic_score_codex":0.0011980924,"about_ca_topic_score_gemma":0.00087479805,"teacher_disagreement_score":0.121303976,"about_ca_system_score_codex":0.0007393825,"about_ca_system_score_gemma":0.0014415708,"threshold_uncertainty_score":0.99949455},"labels":[],"label_agreement":null},{"id":"W2500933326","doi":"10.1016/j.biocel.2016.07.020","title":"Defending the mitochondria: The pathways of mitophagy and mitochondrial-derived vesicles","year":2016,"lang":"en","type":"review","venue":"The International Journal of Biochemistry & Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Mitophagy; Parkin; PINK1; Mitochondrion; Cell biology; Autophagy; Biology; Biochemistry; Parkinson's disease; Apoptosis; Medicine; Disease","score_opus":0.02666065762637406,"score_gpt":0.31330225559135527,"score_spread":0.28664159796498123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2500933326","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.019795004,0.9769912,0.000044718756,0.0010233343,0.0013234362,0.00027866926,0.000101491445,0.0000061479745,0.0004360189],"genre_scores_gemma":[0.019523568,0.9770782,0.00008421982,0.00024053255,0.0027280415,0.000015299776,0.00002602213,0.000026894139,0.00027721978],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981835,0.00019786038,0.0008949995,0.00021265804,0.00031683274,0.00019415432],"domain_scores_gemma":[0.9965809,0.0010848918,0.0015292298,0.00042142032,0.00030160835,0.00008195771],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003532983,0.0003013538,0.0008570051,0.000072975854,0.00009264537,0.000027771406,0.0011987581,0.0002685309,0.00012538751],"category_scores_gemma":[0.0002146089,0.000110330024,0.000692945,0.000079825186,0.00061067566,0.00002652222,0.00018637336,0.0005166562,0.000009204212],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040386277,0.00014384955,0.000011945119,0.00083572697,0.0026140423,0.00008433066,0.00018529194,2.089127e-7,0.615754,0.0001751932,0.002268813,0.3775227],"study_design_scores_gemma":[0.0014818715,0.00021398679,0.000015803273,0.0050203702,0.0012708419,0.0017879395,0.00019880677,0.0000017825416,0.3345729,0.0011660374,0.654052,0.00021764591],"about_ca_topic_score_codex":0.000004322051,"about_ca_topic_score_gemma":2.222856e-7,"teacher_disagreement_score":0.65178317,"about_ca_system_score_codex":0.000080974874,"about_ca_system_score_gemma":0.00046199496,"threshold_uncertainty_score":0.4499128},"labels":[],"label_agreement":null},{"id":"W2515030955","doi":"10.1111/nyas.13190","title":"Autophagy and its current relevance to the diagnosis and clinical management of esophageal diseases","year":2016,"lang":"en","type":"review","venue":"Annals of the New York Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Calgary; St. Michael's Hospital","funders":"","keywords":"Autophagy; Disease; Inflammation; Biology; Clinical significance; Medicine; Degeneration (medical); Esophageal cancer; Cell biology; Immunology; Cancer research; Cancer; Bioinformatics; Pathology; Apoptosis; Genetics","score_opus":0.21358572373056123,"score_gpt":0.4783271755233728,"score_spread":0.26474145179281156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2515030955","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0041795177,0.98876727,0.0000018752188,0.0056307567,0.00018869793,0.0010609285,0.00009834541,0.000008845143,0.000063750995],"genre_scores_gemma":[0.008286968,0.99048245,0.000050324892,0.00056007743,0.00024283426,0.000038370308,6.15657e-7,0.000012089576,0.00032625915],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975342,0.0001989531,0.00089688256,0.00046408505,0.0006454009,0.00026047937],"domain_scores_gemma":[0.99786663,0.0008052245,0.00079870765,0.00023183723,0.000038064547,0.00025954391],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009799192,0.00025916487,0.0011952252,0.00010815912,0.00012024807,0.00001164284,0.0008882817,0.00012853422,0.00002908479],"category_scores_gemma":[0.00022657125,0.00011185246,0.00047017794,0.00050450204,0.0009617687,0.00007766709,0.00039067713,0.00023039088,0.000005865245],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002936524,0.00010658096,0.00032275374,0.0039961226,0.00025093288,7.849544e-7,0.00003333678,3.4341952e-7,3.393643e-7,0.0021891682,0.007918322,0.98515195],"study_design_scores_gemma":[0.00038191196,0.00031044803,0.01858906,0.040469095,0.0012825822,0.000005945667,0.000019927144,0.000004412535,0.00027272085,0.0025018766,0.9359861,0.00017589885],"about_ca_topic_score_codex":0.0000035380285,"about_ca_topic_score_gemma":1.4967691e-7,"teacher_disagreement_score":0.98497605,"about_ca_system_score_codex":0.000006130621,"about_ca_system_score_gemma":0.00015651308,"threshold_uncertainty_score":0.4561211},"labels":[],"label_agreement":null},{"id":"W2517875366","doi":"10.1083/jcb.201511034","title":"PEX2 is the E3 ubiquitin ligase required for pexophagy during starvation","year":2016,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":178,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Peroxisome; Ubiquitin ligase; Ubiquitin; Autophagy; Cell biology; Catabolism; Biology; Biochemistry; Ubiquitin-Protein Ligases; Organelle; Protein degradation; Metabolism; Gene","score_opus":0.02103098510902588,"score_gpt":0.29187726636137856,"score_spread":0.27084628125235266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2517875366","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9895062,0.0013724392,0.0007393776,0.007656777,0.00018993692,0.00021644171,0.00001256036,0.000008115584,0.00029815896],"genre_scores_gemma":[0.99500406,0.0011460138,0.00008640746,0.0016780077,0.0006794997,0.000004623678,0.0000015717143,0.000012692116,0.0013871113],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992054,0.00011874042,0.000326343,0.00007038024,0.00009159615,0.00018750844],"domain_scores_gemma":[0.9988128,0.00039566043,0.00033802545,0.00021426808,0.00017549591,0.00006375329],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006056384,0.00009104952,0.0001986479,0.000049646078,0.00011232899,0.0000043101977,0.0001833333,0.00006685101,0.00024358086],"category_scores_gemma":[0.000098836754,0.00003387728,0.00014384121,0.000052568943,0.00012581446,0.000052146603,0.000021442813,0.00010042537,0.00002050706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018684063,0.000052168158,0.00011916253,0.000018897887,0.000089989495,0.000007945729,0.00046687192,6.62257e-7,0.9926328,0.0001902304,0.0010094312,0.003543444],"study_design_scores_gemma":[0.0028108635,0.0008083338,0.0040928326,0.000052921405,0.00014960507,0.00009982587,0.00015488696,0.000009859601,0.9791392,0.0048389924,0.0077904942,0.000052167445],"about_ca_topic_score_codex":0.0000030137217,"about_ca_topic_score_gemma":7.0269056e-7,"teacher_disagreement_score":0.013493573,"about_ca_system_score_codex":0.00003972557,"about_ca_system_score_gemma":0.00009576911,"threshold_uncertainty_score":0.26670396},"labels":[],"label_agreement":null},{"id":"W2518665037","doi":"10.1016/j.bbalip.2016.09.004","title":"Glucolipotoxicity diminishes cardiomyocyte TFEB and inhibits lysosomal autophagy during obesity and diabetes","year":2016,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saint John Regional Hospital; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Dalhousie University; Fondation de la recherche en santé du Nouveau-Brunswick; Canadian Diabetes Association","keywords":"TFEB; Autophagy; Endocrinology; Internal medicine; Cell biology; Biology; Lysosome; Myocyte; Medicine; Biochemistry; Apoptosis","score_opus":0.0052147766313887555,"score_gpt":0.2231762484993612,"score_spread":0.21796147186797246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2518665037","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969203,0.0016728791,0.000013316752,0.00051700394,0.00008534302,0.00034834121,0.00007910803,0.0000642849,0.0002994518],"genre_scores_gemma":[0.9977236,0.0014890161,0.00014555533,0.00036142732,0.0001452229,0.000021601696,0.000022368598,0.00003226674,0.000058989768],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983383,0.00016054783,0.0003315354,0.0006252611,0.0001379225,0.00040644902],"domain_scores_gemma":[0.9990318,0.00010207528,0.00016395477,0.00036760062,0.000058190402,0.00027637093],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013586797,0.00035767432,0.00068415166,0.00012399456,0.00012142177,0.0000196559,0.00011221637,0.00027453847,0.000014324046],"category_scores_gemma":[0.00003369994,0.00025663746,0.00017136427,0.00011859482,0.0008675234,0.00009030105,0.00022235618,0.00014765818,0.0000032894377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025001273,0.000207321,0.0030539234,0.00021729022,0.0002657616,0.000012536036,0.00012361613,3.2962173e-8,0.9946635,0.00016695075,0.000012737296,0.0010263232],"study_design_scores_gemma":[0.0021072824,0.00060940237,0.13831882,0.00010631184,0.00021318703,0.000014372333,0.000022251428,0.000008710972,0.8579378,0.0003236956,0.000077108874,0.00026104404],"about_ca_topic_score_codex":0.000012099918,"about_ca_topic_score_gemma":5.487847e-7,"teacher_disagreement_score":0.13672568,"about_ca_system_score_codex":0.0000166329,"about_ca_system_score_gemma":0.00006330475,"threshold_uncertainty_score":0.99998856},"labels":[],"label_agreement":null},{"id":"W2522026215","doi":"10.1016/j.bbamcr.2016.09.015","title":"Inhibition of autophagy sensitises cells to hydrogen peroxide-induced apoptosis: Protective effect of mild thermotolerance acquired at 40 °C","year":2016,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Apoptosis; Cell biology; Programmed cell death; Oxidative stress; Reactive oxygen species; Unfolded protein response; Endoplasmic reticulum; Bafilomycin; Chemistry; HeLa; Biology; Cell; Biochemistry","score_opus":0.02379228786986489,"score_gpt":0.3198272234736492,"score_spread":0.29603493560378435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2522026215","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99482316,0.00019361127,0.000069164504,0.00078692427,0.000053763422,0.003181761,0.00010700531,0.000072609524,0.00071202376],"genre_scores_gemma":[0.99877036,0.00011600108,0.00012707626,0.00019130779,0.00009010277,0.00031117094,0.00002643239,0.00011311016,0.00025443206],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9952878,0.0011363518,0.0005584526,0.0008804386,0.0013721513,0.0007648363],"domain_scores_gemma":[0.9973206,0.0003852997,0.00025170215,0.0011220899,0.00050348,0.0004168382],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00082921464,0.00044373923,0.00083935936,0.0004580197,0.00013850768,0.000019366147,0.0003323185,0.000273561,0.00007715601],"category_scores_gemma":[0.00013711948,0.0003190135,0.00048082788,0.0008520636,0.00041113718,0.000106566775,0.00032167952,0.00025863101,0.00012588716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004564508,0.0006148598,0.0000021793855,0.0004493404,0.00028137898,0.000059506525,0.00055293523,0.0000018643383,0.9920634,0.000020127653,0.00013017644,0.0012597442],"study_design_scores_gemma":[0.0033090208,0.0035760126,0.0007957458,0.00079226604,0.000121558085,0.0000043658138,0.00004081319,0.000027511676,0.99089515,0.000112861155,0.000019322095,0.00030538245],"about_ca_topic_score_codex":0.00007870113,"about_ca_topic_score_gemma":0.000001165737,"teacher_disagreement_score":0.0039472296,"about_ca_system_score_codex":0.00023692509,"about_ca_system_score_gemma":0.00028089347,"threshold_uncertainty_score":0.9999262},"labels":[],"label_agreement":null},{"id":"W2524938670","doi":"10.1016/j.freeradbiomed.2016.09.026","title":"Perturbation of redox balance after thioredoxin reductase deficiency interrupts autophagy-lysosomal degradation pathway and enhances cell death in nutritionally stressed SH-SY5Y cells","year":2016,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Research Manitoba","keywords":"Autophagy; Cell biology; Thioredoxin; Programmed cell death; Thioredoxin reductase; Oxidative stress; Proteasome; Apoptosis; Protein degradation; Biology; Chemistry; Biochemistry","score_opus":0.01016416435142295,"score_gpt":0.26579025652567223,"score_spread":0.25562609217424925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2524938670","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98305935,0.011927403,0.00053100643,0.0035349333,0.00015710604,0.00028087123,0.00009010284,0.000022929382,0.00039628203],"genre_scores_gemma":[0.9957031,0.0025585517,0.0005944698,0.0004924402,0.00018905704,0.000037861824,0.000078867175,0.000009033028,0.00033659014],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987384,0.000112002665,0.00040856318,0.0003630399,0.00015275643,0.00022520708],"domain_scores_gemma":[0.9991763,0.00025806602,0.00012275708,0.00021543234,0.00005845594,0.00016896032],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024577032,0.00017290251,0.00039401345,0.00015849614,0.000039229577,0.0000023695534,0.00009231987,0.00020850691,0.00026733972],"category_scores_gemma":[0.00022771994,0.0001016749,0.000037802187,0.0001166904,0.00072698644,0.00008015757,0.000033307733,0.00014038642,0.000002391087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012739872,0.0004133526,0.023410639,0.00017393884,0.000027371072,0.000074434276,0.0003245529,5.697292e-8,0.96209145,0.0037713721,0.00034545807,0.008093383],"study_design_scores_gemma":[0.013870923,0.002994954,0.35667044,0.0016038213,0.00013022622,0.0000834508,0.00014342924,0.00013544978,0.6024365,0.020364922,0.0012776261,0.00028829018],"about_ca_topic_score_codex":0.000025989717,"about_ca_topic_score_gemma":0.0000081859935,"teacher_disagreement_score":0.359655,"about_ca_system_score_codex":0.00002944808,"about_ca_system_score_gemma":0.00008840782,"threshold_uncertainty_score":0.4146182},"labels":[],"label_agreement":null},{"id":"W2526211783","doi":"10.1186/s12885-016-2790-3","title":"Role of autophagy and lysosomal drug sequestration in acquired resistance to doxorubicin in MCF-7 cells","year":2016,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"NOSM University; University of Ottawa; Laurentian University; Health Sciences North","funders":"","keywords":"Autophagy; Surgical oncology; Doxorubicin; Drug resistance; Medicine; Cancer research; MCF-7; Drug; Pharmacology; Oncology; Internal medicine; Chemotherapy; Biology; Cancer; Cancer cell; Apoptosis; Biochemistry; Microbiology","score_opus":0.010253289302139082,"score_gpt":0.2785019399139528,"score_spread":0.2682486506118137,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2526211783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99509025,0.0031425979,0.000027679547,0.00041260323,0.000054671484,0.00032143228,0.00002048924,0.000015634023,0.000914672],"genre_scores_gemma":[0.9969561,0.00023693114,0.0002861481,0.00025822772,0.00007900532,0.00006759462,0.0000015296673,0.000012225613,0.002102246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992392,0.000037112422,0.00022847511,0.00020313311,0.0001315153,0.00016058056],"domain_scores_gemma":[0.9996254,0.000043838485,0.000053535903,0.00016968828,0.00002931552,0.00007822971],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010807283,0.00009011932,0.00020765993,0.000106742926,0.000010078401,0.0000041892717,0.000046038538,0.00004791722,0.00014377812],"category_scores_gemma":[0.000016138458,0.00006741077,0.000026099,0.00016138023,0.0000402869,0.00008373239,0.00001437888,0.00002886906,0.0000066337016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010940986,0.00008975714,0.06895726,0.00008486204,0.00001535285,0.000017392285,0.00090979296,0.000016584061,0.9244054,0.00061805587,0.00035705278,0.0034344003],"study_design_scores_gemma":[0.0019404945,0.000040791365,0.45066234,0.00043831044,0.000011974451,6.3774206e-7,0.000067227396,0.000030246765,0.54520017,0.00071129267,0.000818246,0.000078249395],"about_ca_topic_score_codex":0.00040206753,"about_ca_topic_score_gemma":0.003826592,"teacher_disagreement_score":0.38170508,"about_ca_system_score_codex":0.000119087774,"about_ca_system_score_gemma":0.00018246622,"threshold_uncertainty_score":0.27489316},"labels":[],"label_agreement":null},{"id":"W2527121904","doi":"10.1016/j.cjca.2016.07.384","title":"SELECTIVE DELETION OF ENDOTHELIAL AUTOPHAGY RELATED 7 (ATG7) INHIBITS THROMBUS FORMATION IN MICE","year":2016,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Toronto Public Health","funders":"","keywords":"Autophagy; Medicine; Thrombus; Hemostasis; Knockout mouse; Platelet; Thrombosis; Intracellular; Platelet activation; Cell biology; Endothelial stem cell; Stroke (engine); Internal medicine; Receptor; Apoptosis; In vitro; Biology; Biochemistry","score_opus":0.009801405464149024,"score_gpt":0.23727204232714535,"score_spread":0.22747063686299634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2527121904","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941889,0.00050933135,0.00086938933,0.00045888158,0.0002925527,0.00012485376,0.000018753242,0.0000036913732,0.0035336239],"genre_scores_gemma":[0.9994349,0.00009564174,0.000044674114,0.00010095796,0.00018912941,0.0000015837853,0.0000033566632,0.000009480415,0.00012029657],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990631,0.0001273967,0.00043557404,0.00007809699,0.00008852292,0.00020735817],"domain_scores_gemma":[0.99915624,0.000059231064,0.00023360517,0.00008250758,0.000246489,0.0002219035],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025254575,0.000082692124,0.00039081057,0.00037389537,0.000023293029,0.0000020864638,0.000064230306,0.00014674723,0.00006279626],"category_scores_gemma":[0.00014109586,0.000059275353,0.00013572734,0.00014049954,0.00010272552,0.00013389371,0.0000030785975,0.00016747785,0.000009652826],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018762059,0.000048668033,0.11160737,0.000122001606,0.0015144399,0.00206952,0.006488702,0.0007467539,0.8108715,0.0036442736,0.008338968,0.052671637],"study_design_scores_gemma":[0.011295678,0.0018384273,0.6090223,0.0006495584,0.00023136953,0.004844112,0.00021011927,0.000024275396,0.348914,0.006613108,0.0161087,0.0002483595],"about_ca_topic_score_codex":0.0012192351,"about_ca_topic_score_gemma":0.004219537,"teacher_disagreement_score":0.49741492,"about_ca_system_score_codex":0.00044226443,"about_ca_system_score_gemma":0.0012178043,"threshold_uncertainty_score":0.24171788},"labels":[],"label_agreement":null},{"id":"W2528435810","doi":"10.1016/j.cjca.2015.07.476","title":"ENDOTHELIAL AUTOPHAGY IS ESSENTIAL FOR VASCULAR LIPID HOMEOSTASIS","year":2015,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Toronto Public Health","funders":"","keywords":"Autophagy; Medicine; Homeostasis; Lipid metabolism; In vivo; Gene knockdown; Endothelial dysfunction; Cell biology; Internal medicine; Endocrinology; Biochemistry; Biology; Apoptosis","score_opus":0.024840951672339132,"score_gpt":0.27764378562339675,"score_spread":0.2528028339510576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2528435810","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93664235,0.017687064,0.024159107,0.005169976,0.0070571746,0.0007379754,0.0004292838,0.00002850679,0.008088543],"genre_scores_gemma":[0.99197966,0.00015946779,0.00043308272,0.0014376503,0.0057194293,0.0000070879955,0.000012419898,0.00002666234,0.00022454213],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989765,0.00007338346,0.00031330562,0.00013046068,0.00015013917,0.00035621205],"domain_scores_gemma":[0.99795645,0.000042788368,0.00012555106,0.00021506882,0.0004425481,0.0012175884],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003845819,0.00012684375,0.00056525937,0.00026070166,0.00006034855,0.000014461325,0.0001473783,0.00015192544,0.00009648018],"category_scores_gemma":[0.00021188162,0.00010883348,0.00050974434,0.00008704406,0.0001337118,0.000060146253,0.0000057795673,0.0001663319,0.000023289478],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029372436,0.00005309813,0.016607145,0.00018429976,0.009134889,0.004438128,0.0033160683,0.0010957697,0.0050174952,0.0036192408,0.8459049,0.10769176],"study_design_scores_gemma":[0.005133033,0.0008766913,0.004420203,0.000026932406,0.00048985315,0.0010689832,0.00016698924,0.000025841617,0.0053917565,0.0013119543,0.9809495,0.00013822872],"about_ca_topic_score_codex":0.00022004063,"about_ca_topic_score_gemma":0.00006825811,"teacher_disagreement_score":0.13504466,"about_ca_system_score_codex":0.00015439387,"about_ca_system_score_gemma":0.003219116,"threshold_uncertainty_score":0.5710573},"labels":[],"label_agreement":null},{"id":"W2531380752","doi":"10.1139/apnm-2016-0280","title":"Moderate physical activity promotes basal hepatic autophagy in diet-induced obese mice","year":2016,"lang":"en","type":"article","venue":"Applied Physiology Nutrition and Metabolism","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"University of Arkansas","keywords":"Internal medicine; Steatosis; Autophagy; Endocrinology; Basal (medicine); Inflammation; Fatty liver; Cirrhosis; Obesity; Biology; Medicine; Diabetes mellitus; Apoptosis; Disease; Biochemistry","score_opus":0.016524481277191208,"score_gpt":0.277817511281042,"score_spread":0.2612930300038508,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2531380752","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99766666,0.0004241858,0.000053968382,0.00076552614,0.000092530005,0.00066625397,0.000017436972,0.00007983483,0.00023362432],"genre_scores_gemma":[0.9978872,0.00048596927,0.0001041452,0.0006900805,0.000375024,0.0003535831,0.000015954512,0.000024996187,0.00006308138],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988724,0.0000897489,0.00015873839,0.00043242515,0.00012046215,0.0003262479],"domain_scores_gemma":[0.9993925,0.00011209245,0.00007250807,0.00023005065,0.000037905207,0.00015496137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000075958975,0.00022825222,0.0005577812,0.00010570142,0.000070356706,0.00000799757,0.00006330552,0.00014560409,0.000051656683],"category_scores_gemma":[0.000018016288,0.00015647488,0.00008857323,0.00014119442,0.00013541449,0.00010799282,0.000037763544,0.0001789937,0.000043003387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013428428,0.0016019595,0.000014259683,0.000081131286,0.000062305044,0.000009248824,0.00015343034,1.4158472e-7,0.97666085,0.004999144,0.00003998452,0.015034678],"study_design_scores_gemma":[0.011379452,0.00010146278,0.35699424,0.00009757957,0.00010318718,0.000005734918,0.00003008438,0.00067472464,0.59638256,0.03324929,0.0007202577,0.00026143985],"about_ca_topic_score_codex":0.000017109067,"about_ca_topic_score_gemma":0.0000019748356,"teacher_disagreement_score":0.38027832,"about_ca_system_score_codex":0.000022845354,"about_ca_system_score_gemma":0.000048191443,"threshold_uncertainty_score":0.6380861},"labels":[],"label_agreement":null},{"id":"W2535993440","doi":"10.1002/cam4.929","title":"Variants in autophagy‐related genes and clinical characteristics in melanoma: a population‐based study","year":2016,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency; Cancer Care Ontario","funders":"National Institute of Environmental Health Sciences; National Institute of General Medical Sciences; University of New Mexico; BC Cancer Agency; University of California, Irvine; University of North Carolina at Chapel Hill; National Institutes of Health; Missouri Department of Health and Senior Services; Menzies Institute for Medical Research; Cancer Care Ontario; University of Tasmania; University of Pennsylvania; National Cancer Institute; State of New Jersey Department of Health","keywords":"Autophagy; Gene; Biology; Genetics; Melanoma; Population; Medicine; Oncology; Cancer research; Environmental health","score_opus":0.03376729186725145,"score_gpt":0.3745167850583187,"score_spread":0.34074949319106723,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2535993440","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99397063,0.0023304871,0.000023012746,0.0024840394,0.00044481122,0.00059552863,0.0000111542495,0.000037113332,0.00010321404],"genre_scores_gemma":[0.9977316,0.000669095,0.000021698019,0.00083017035,0.0003055389,0.000058170895,0.000017195134,0.000021820922,0.00034469774],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99841154,0.0001264373,0.0007014825,0.00033760272,0.00020904357,0.00021387474],"domain_scores_gemma":[0.9991972,0.0001899789,0.00012945257,0.00026571416,0.0000446874,0.00017296728],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051042193,0.00015792296,0.00059722125,0.00020942414,0.00002228302,0.0000028368281,0.0000662421,0.000113856506,0.00077940436],"category_scores_gemma":[0.00023125844,0.00009620564,0.00003236477,0.00026822576,0.000087976645,0.000052616244,0.000018912042,0.00015698861,0.000009992008],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003966786,0.0004330158,0.9474085,0.000025644476,0.00006106877,0.00038715455,0.00021966029,2.9847294e-7,0.00053158513,0.000033948705,0.00004523717,0.050457194],"study_design_scores_gemma":[0.016210044,0.0006493587,0.981582,0.00063406426,0.000117185504,0.000006117995,0.000062434876,0.0002825958,0.000040247858,0.00013156477,0.00017735692,0.00010703834],"about_ca_topic_score_codex":0.0003477302,"about_ca_topic_score_gemma":0.00016913547,"teacher_disagreement_score":0.050350156,"about_ca_system_score_codex":0.00012661392,"about_ca_system_score_gemma":0.00015343461,"threshold_uncertainty_score":0.85339314},"labels":[],"label_agreement":null},{"id":"W2539923879","doi":"10.1097/qai.0000000000001201","title":"Brief Report: Impaired CD4 T-Cell Response to Autophagy in Treated HIV-1–Infected Individuals","year":2016,"lang":"en","type":"article","venue":"JAIDS Journal of Acquired Immune Deficiency Syndromes","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Autophagy; Cd4 t cell; Immunology; T cell; Human immunodeficiency virus (HIV); Biology; Medicine; Virology; Immune system; Apoptosis; Genetics","score_opus":0.013035633552804132,"score_gpt":0.27486298798904907,"score_spread":0.26182735443624494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2539923879","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935137,0.002729321,0.00024234112,0.0020122873,0.00039005242,0.0005263789,0.000035676134,0.00013757065,0.0004126779],"genre_scores_gemma":[0.9914616,0.00019194344,0.00047636178,0.00021353974,0.000069097005,0.0000203429,0.000011569417,0.00008239149,0.0074731507],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99539286,0.0004402739,0.0020330397,0.0004554242,0.00091079,0.00076764135],"domain_scores_gemma":[0.9967058,0.0006268495,0.00095127424,0.00085684616,0.00041679962,0.00044247796],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0027112546,0.00042562364,0.0012061715,0.0017684039,0.00011179037,0.00005118521,0.00046659086,0.00023656066,0.00052153174],"category_scores_gemma":[0.001914809,0.0002835609,0.0005261308,0.0018233462,0.00017955147,0.000429689,0.0001034179,0.00016214541,0.00020350114],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0068990216,0.0020861381,0.10362397,0.000072168405,0.00033009853,0.02134259,0.0016838983,0.00003095049,0.8533481,0.000027675984,0.0042928364,0.0062625664],"study_design_scores_gemma":[0.009328297,0.0034443906,0.863517,0.00089407247,0.00021019299,0.008902395,0.0002527351,0.000010371787,0.111020766,0.00015407342,0.0018719622,0.0003937623],"about_ca_topic_score_codex":0.000025707723,"about_ca_topic_score_gemma":7.954971e-7,"teacher_disagreement_score":0.759893,"about_ca_system_score_codex":0.0003540862,"about_ca_system_score_gemma":0.00069629936,"threshold_uncertainty_score":0.9999617},"labels":[],"label_agreement":null},{"id":"W2543080982","doi":"10.4238/gmr15048953","title":"Inhibition of Atg6 and Pi3K59F autophagy genes in neurons decreases lifespan and locomotor ability in Drosophila melanogaster","year":2016,"lang":"en","type":"article","venue":"Genetics and Molecular Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Memorial University of Newfoundland","keywords":"Drosophila melanogaster; Autophagy; Biology; Longevity; Cell biology; Melanogaster; RNA interference; Context (archaeology); Aromatic L-amino acid decarboxylase; Gene; Genetics; Neuroscience; RNA","score_opus":0.032789329144367566,"score_gpt":0.3420715466487257,"score_spread":0.30928221750435814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2543080982","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904617,0.008144884,0.000041317482,0.00084940443,0.000008575798,0.00041224263,0.000017626126,0.0000039479573,0.00006032409],"genre_scores_gemma":[0.99451256,0.005193161,0.00010630905,0.000101393634,0.000016149377,0.000026621025,0.00000386932,0.000014364603,0.000025592786],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988976,0.00015476946,0.00019125167,0.0002886563,0.00023574586,0.00023194827],"domain_scores_gemma":[0.9993931,0.00008326931,0.000027784328,0.00025159455,0.00006613672,0.00017809932],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035349076,0.000094484814,0.00018733204,0.0001555837,0.000042653242,0.000019844947,0.000043828644,0.000075787175,0.000017860724],"category_scores_gemma":[0.00010335414,0.00007176511,0.000020735757,0.00009242882,0.0003855598,0.00002883306,0.00014071554,0.000100298734,7.0313115e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019422591,0.00017004705,0.13169467,0.00010265365,0.000013347365,0.00012394914,0.00009804361,3.2400965e-7,0.8462666,0.00014694757,0.000015872978,0.021173313],"study_design_scores_gemma":[0.0025829156,0.00051514304,0.6143055,0.00015117407,0.000011103382,0.000016234342,0.000034762445,0.000114351795,0.37995216,0.0019647907,0.00026957018,0.000082330705],"about_ca_topic_score_codex":0.00009427845,"about_ca_topic_score_gemma":0.000031362975,"teacher_disagreement_score":0.4826108,"about_ca_system_score_codex":0.000016745304,"about_ca_system_score_gemma":0.000059803635,"threshold_uncertainty_score":0.29264963},"labels":[],"label_agreement":null},{"id":"W2548552719","doi":"10.18632/oncotarget.13121","title":"Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE−/− mice","year":2016,"lang":"en","type":"article","venue":"Oncotarget","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"Construct Program of the Key Discipline in Hunan Province; Science and Technology Innovative Research Team in Higher Educational Institutions of Hunan Province; University of South China; Chongqing University; National Natural Science Foundation of China","keywords":"Autophagy; Downregulation and upregulation; Inflammation; Apolipoprotein E; Medicine; Immunology; Internal medicine; Cancer research; Biology; Gene; Genetics; Disease; Apoptosis","score_opus":0.011086456770397102,"score_gpt":0.26104930124598086,"score_spread":0.24996284447558376,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2548552719","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963721,0.0007490612,0.0009851647,0.0006746766,0.00012750531,0.00034025332,0.000037826037,0.00006462551,0.00064876],"genre_scores_gemma":[0.99684525,0.0001720737,0.0012327504,0.0003914909,0.00014099157,0.000029236224,0.000029729332,0.000037914837,0.0011205961],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986243,0.000078602185,0.00043409076,0.00029945537,0.00028987264,0.00027368116],"domain_scores_gemma":[0.999143,0.00009715365,0.00015504782,0.00037142783,0.000087340944,0.00014604698],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024323545,0.0001892403,0.00041499507,0.0001642329,0.000028445225,0.000004520403,0.000099824625,0.00013566815,0.00070718856],"category_scores_gemma":[0.00007385781,0.00013089008,0.00013732085,0.00031054835,0.00008919604,0.00015252232,0.000034418674,0.0000860847,0.00008617629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003251449,0.00043623848,0.030175196,0.000050760544,0.000060227485,0.000010782936,0.00023453419,0.000005566626,0.96239907,0.00017954901,0.0004951566,0.0056277867],"study_design_scores_gemma":[0.0031976975,0.00019988764,0.33394298,0.00023229182,0.000034024724,0.0000045687075,0.0000117663,0.000103303755,0.66001606,0.0006637208,0.0014685605,0.00012514101],"about_ca_topic_score_codex":0.00007238232,"about_ca_topic_score_gemma":0.000011574902,"teacher_disagreement_score":0.30376777,"about_ca_system_score_codex":0.00011917325,"about_ca_system_score_gemma":0.00009130071,"threshold_uncertainty_score":0.7743219},"labels":[],"label_agreement":null},{"id":"W2549312732","doi":"10.1016/bs.mie.2016.09.079","title":"Assessment of Glycolytic Flux and Mitochondrial Respiration in the Course of Autophagic Responses","year":2016,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Cancer Research; Institut Gustave-Roussy; Fondation Bettencourt Schueller; Institut National Du Cancer; Agence Nationale de la Recherche","keywords":"Autophagy; Flux (metallurgy); Cell biology; Homeostasis; Mitochondrion; Biology; Glycolysis; Cytoplasm; Metabolism; Biochemistry; Chemistry; Apoptosis","score_opus":0.0571209397090876,"score_gpt":0.4735902970185955,"score_spread":0.4164693573095079,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2549312732","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9641353,0.0015346685,0.029013358,0.0016662474,0.00094917504,0.0012196919,0.000025174479,0.00003262109,0.001423761],"genre_scores_gemma":[0.57083523,0.00015242133,0.4275907,0.0008368606,0.00010812471,0.00020597072,0.000006122843,0.00003544999,0.00022915147],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9776376,0.018789077,0.001680933,0.0008867679,0.00032417764,0.00068144134],"domain_scores_gemma":[0.98237944,0.015666867,0.00058795995,0.0011274769,0.00012831978,0.00010995731],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.011622056,0.00044706964,0.0016437917,0.0011663276,0.000054279535,0.000006947127,0.0004826873,0.00079135894,0.00030561176],"category_scores_gemma":[0.004715636,0.00029272898,0.00019234371,0.00088649243,0.0013373063,0.00009937424,0.0001373675,0.00081538904,0.0000030400633],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004292847,0.0017245508,0.045472104,0.00012742571,0.00012523381,0.00046849786,0.0012402723,0.000038627477,0.85554165,0.020450076,0.00012789363,0.07039082],"study_design_scores_gemma":[0.007950276,0.0033168534,0.8939462,0.00026448257,0.000112240974,0.00035537756,0.00025998126,0.000113928865,0.055853594,0.036916547,0.0006374492,0.00027312705],"about_ca_topic_score_codex":0.00012696015,"about_ca_topic_score_gemma":0.00027977777,"teacher_disagreement_score":0.848474,"about_ca_system_score_codex":0.00022574406,"about_ca_system_score_gemma":0.000519165,"threshold_uncertainty_score":0.9999525},"labels":[],"label_agreement":null},{"id":"W2550761263","doi":"10.1016/j.bbamcr.2016.11.023","title":"Gambogic acid counteracts mutant p53 stability by inducing autophagy","year":2016,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Johns Hopkins University; Associazione Italiana per la Ricerca sul Cancro; Ministry of Health, British Columbia; Compagnia di San Paolo","keywords":"Autophagy; Cell biology; Gambogic acid; Apoptosis; Programmed cell death; Cancer cell; Gene knockdown; Cell growth; Cell culture; Protein degradation; Chemistry; Cell; Mutant; Bafilomycin; Biology; Biochemistry; Cancer; Genetics; Gene","score_opus":0.04463732256182245,"score_gpt":0.34932725027511186,"score_spread":0.3046899277132894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2550761263","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882805,0.0007750631,0.000177801,0.0041983,0.00013973832,0.0011377203,0.00020943752,0.00018003113,0.004901427],"genre_scores_gemma":[0.99669594,0.00062022253,0.00016474567,0.0011400094,0.00018437307,0.00012223732,0.00014315291,0.00013052396,0.0007987939],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99406224,0.00076740404,0.000598687,0.0013028277,0.0018916441,0.0013772068],"domain_scores_gemma":[0.99633694,0.0004094553,0.00018179386,0.0017414062,0.0005342135,0.00079617515],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012385831,0.0005281889,0.0006578936,0.0003269603,0.00027439106,0.00014230267,0.0006875873,0.00033418016,0.0008309164],"category_scores_gemma":[0.00031547464,0.00037604754,0.0003938973,0.0008310398,0.00064925215,0.0002598715,0.00037340456,0.00090903277,0.00045682618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00072235876,0.0013269365,0.000009774634,0.00013121827,0.00017684748,0.00029174815,0.00033828247,1.1427401e-7,0.99307734,0.00013664295,0.0021933876,0.0015953757],"study_design_scores_gemma":[0.0024158543,0.0008690415,0.0008493929,0.00022131318,0.00007390807,0.000014399269,0.00011225409,0.000058227615,0.99167764,0.00059828785,0.0026758746,0.00043382618],"about_ca_topic_score_codex":0.00007095073,"about_ca_topic_score_gemma":0.0000014711075,"teacher_disagreement_score":0.00841546,"about_ca_system_score_codex":0.00041587296,"about_ca_system_score_gemma":0.0008420533,"threshold_uncertainty_score":0.99986917},"labels":[],"label_agreement":null},{"id":"W2552042455","doi":"10.1016/j.jmb.2016.11.009","title":"S100A10 Regulates ULK1 Localization to ER–Mitochondria Contact Sites in IFN-γ-Triggered Autophagy","year":2016,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Ministry of Science and Technology, Taiwan","keywords":"Autophagy; Autophagosome; Cell biology; ULK1; Gene knockdown; Gene silencing; BECN1; Biology; Chemistry; Biochemistry; Apoptosis; Kinase; Protein kinase A; Gene","score_opus":0.009461054263433301,"score_gpt":0.3023114740039816,"score_spread":0.2928504197405483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2552042455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96845233,0.0028448575,0.025912868,0.0021558844,0.00027112244,0.00021764332,0.000005605576,0.000015684016,0.00012399617],"genre_scores_gemma":[0.99656254,0.00017128942,0.0008189373,0.0020556387,0.0001924074,0.000004748047,0.0000074458476,0.000021352042,0.00016563242],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986671,0.00015739111,0.0005898269,0.000182178,0.00015307323,0.0002504296],"domain_scores_gemma":[0.9990111,0.00009311247,0.00026506063,0.00022362036,0.00020032027,0.00020677506],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024024994,0.00015163087,0.0004749765,0.00034351004,0.000022202654,0.000007945323,0.0001417104,0.00018683738,0.0002966425],"category_scores_gemma":[0.00036660698,0.000093858034,0.00016919397,0.00022204153,0.000049312937,0.00007214966,0.000026992042,0.0001267056,0.000039118677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000817749,0.00015399624,0.005805027,0.000010781945,0.00013853425,0.0004230131,0.00009719307,0.000020986081,0.98226243,0.0010420108,0.0008887193,0.008339529],"study_design_scores_gemma":[0.005451433,0.0022646638,0.036225986,0.0003099374,0.00009571356,0.00031360865,0.000033294735,0.000051930256,0.9388152,0.006982804,0.009263358,0.00019209886],"about_ca_topic_score_codex":0.000007398087,"about_ca_topic_score_gemma":0.0000051006946,"teacher_disagreement_score":0.043447286,"about_ca_system_score_codex":0.00010145971,"about_ca_system_score_gemma":0.00015277983,"threshold_uncertainty_score":0.38274196},"labels":[],"label_agreement":null},{"id":"W2553106647","doi":"10.1038/srep37052","title":"Bafilomycin A1 induces caspase-independent cell death in hepatocellular carcinoma cells via targeting of autophagy and MAPK pathways","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"National Science and Technology Planning Project; National Natural Science Foundation of China","keywords":"Programmed cell death; Autophagy; Cancer research; Apoptosis; Cytotoxicity; Puma; Cyclin D1; Bafilomycin; MAPK/ERK pathway; Cell growth; Downregulation and upregulation; Cell cycle checkpoint; Cell cycle; Biology; Chemistry; Kinase; Cell biology; In vitro; Biochemistry","score_opus":0.016941998761685537,"score_gpt":0.23140704964119096,"score_spread":0.21446505087950543,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2553106647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99532694,0.0016035811,0.00013141603,0.00004136872,0.0015296241,0.0005313239,0.000008040382,0.000044052573,0.00078365824],"genre_scores_gemma":[0.99798673,0.000029083581,0.00037038824,0.000032495893,0.000071829934,0.00002222913,0.000020689875,0.000029618275,0.0014369246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972244,0.00007438727,0.0007931481,0.0008409194,0.0006284245,0.00043875416],"domain_scores_gemma":[0.9983685,0.000055314107,0.00040803294,0.0007405211,0.00013996809,0.00028767102],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012747175,0.00023240075,0.00043579843,0.00031712337,0.00011722422,0.000040046714,0.000103807535,0.00013894675,0.00023812147],"category_scores_gemma":[0.000056290806,0.0001640126,0.00012334115,0.00029707188,0.00019986129,0.00015689938,0.000093791015,0.00013425158,0.000019437117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003669154,0.00047178243,0.10299871,0.00011526015,0.000016083493,0.0053507574,0.0005418851,8.666634e-7,0.8889894,0.000027884604,0.0003362281,0.0011144383],"study_design_scores_gemma":[0.0015440397,0.00009877182,0.033394486,0.00014143193,0.00004075075,0.00020994285,0.00010550284,0.00017902842,0.96158767,0.001987716,0.0005236583,0.0001869863],"about_ca_topic_score_codex":0.00015078094,"about_ca_topic_score_gemma":0.000006016067,"teacher_disagreement_score":0.07259827,"about_ca_system_score_codex":0.00008993057,"about_ca_system_score_gemma":0.00031546917,"threshold_uncertainty_score":0.66882396},"labels":[],"label_agreement":null},{"id":"W2554496886","doi":"10.1016/bs.mie.2016.09.073","title":"Measurement of Autolysosomal pH by Dual-Wavelength Ratio Imaging","year":2016,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Hospital for Sick Children; Toronto Metropolitan University","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute for Health and Care Research","keywords":"Fluorescence; Photobleaching; Biophysics; Chemistry; Organelle; Membrane; Fluorescence microscope; Homeostasis; Fluorescence recovery after photobleaching; Biochemistry; Cell biology; Biology; Optics; Physics","score_opus":0.047776746599641866,"score_gpt":0.4058633137698757,"score_spread":0.35808656717023385,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2554496886","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5846276,0.008745615,0.38871324,0.004975893,0.003423384,0.002012573,0.00006703641,0.00034087044,0.00709375],"genre_scores_gemma":[0.4540434,0.00046422041,0.5424119,0.002022909,0.0002094425,0.0002730747,0.000012610034,0.00012024685,0.00044219586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9830672,0.011186569,0.0021117432,0.0015404058,0.00063935004,0.0014547305],"domain_scores_gemma":[0.992755,0.0043858434,0.0006956127,0.0015078116,0.00031667837,0.00033904277],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.012667383,0.0008197967,0.0023369445,0.00130906,0.00010605008,0.000011500159,0.0005597015,0.00089096377,0.0009938488],"category_scores_gemma":[0.005406853,0.0006468426,0.0004003639,0.0009039156,0.0012089615,0.00016755979,0.00024194054,0.0011113638,0.0000432983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013316745,0.001312589,0.013665052,0.00010181115,0.00025963478,0.00059293356,0.0004411685,0.00001056363,0.7254996,0.007415494,0.0009369227,0.2484326],"study_design_scores_gemma":[0.015762562,0.0024937561,0.2703526,0.00066181907,0.00032659422,0.0011419553,0.0002829973,0.0003841162,0.654257,0.044260245,0.008830279,0.0012460691],"about_ca_topic_score_codex":0.00013483125,"about_ca_topic_score_gemma":0.00007192721,"teacher_disagreement_score":0.25668755,"about_ca_system_score_codex":0.0007015315,"about_ca_system_score_gemma":0.0004832572,"threshold_uncertainty_score":0.99991935},"labels":[],"label_agreement":null},{"id":"W2554795215","doi":"10.1007/s10565-016-9369-2","title":"Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing indole-based chalcones","year":2016,"lang":"en","type":"article","venue":"Cell Biology and Toxicology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; McMaster University","keywords":"Cell biology; Vacuolization; Autophagy; Programmed cell death; Viability assay; Endosome; Secretion; Biology; Endocytic cycle; Cancer cell; Aggresome; Chemistry; Apoptosis; Receptor; Biochemistry; Endocytosis; Cancer; Intracellular","score_opus":0.017638384463759184,"score_gpt":0.2726145629768374,"score_spread":0.2549761785130782,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2554795215","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99659747,0.0018563938,0.0003458802,0.00036270524,0.0001800589,0.00023297212,0.000029716002,0.00002964781,0.0003651864],"genre_scores_gemma":[0.99924433,0.00019209535,0.00010336128,0.0003071847,0.000060685765,0.000029243089,0.000020973584,0.000012582468,0.000029548777],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988658,0.00018237146,0.00030304934,0.00031670748,0.00004326369,0.00028882388],"domain_scores_gemma":[0.9992531,0.00035007004,0.00013120876,0.00015143676,0.000025159521,0.00008906012],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021610707,0.00015309908,0.00040797764,0.00019176754,0.000039412716,0.0000018546061,0.00006722649,0.00036348143,0.00014280551],"category_scores_gemma":[0.000030994597,0.00010446281,0.00007133848,0.00011464109,0.0002849411,0.000034664943,0.000024008436,0.0001195751,0.000008268907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042367322,0.0003630485,0.014528444,0.000046240835,0.000030769785,0.000042128842,0.00012691939,0.0000013037046,0.963703,0.0005060029,0.000017138633,0.020211365],"study_design_scores_gemma":[0.0047387066,0.00093171606,0.0121284155,0.000054668675,0.000040452735,0.000013837997,0.00006616503,0.000050729013,0.981262,0.00030129164,0.0002968201,0.000115185874],"about_ca_topic_score_codex":0.000008023523,"about_ca_topic_score_gemma":0.0000057930965,"teacher_disagreement_score":0.02009618,"about_ca_system_score_codex":0.000025735657,"about_ca_system_score_gemma":0.00006592786,"threshold_uncertainty_score":0.42598698},"labels":[],"label_agreement":null},{"id":"W2556612079","doi":"10.1016/j.bbrc.2016.11.015","title":"The small molecule 2-phenylethynesulfonamide induces covalent modification of p53","year":2016,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Coastal Health","funders":"Canadian Institutes of Health Research","keywords":"Covalent bond; Small molecule; Suppressor; Chemistry; Nucleus; P53 protein; Cytosol; Molecule; Biophysics; Apoptosis; Molecular mass; Biochemistry; Cell biology; Molecular biology; Biology; Enzyme; Gene","score_opus":0.1425667555774074,"score_gpt":0.4085918820886572,"score_spread":0.2660251265112498,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2556612079","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9760685,0.002322221,0.00008827699,0.020244403,0.0000089867735,0.00027687382,0.000021112044,0.000021084723,0.00094854954],"genre_scores_gemma":[0.9934237,0.0056622517,0.0002886587,0.00006173937,0.000050808223,0.00008818883,0.000017419361,0.0000087127155,0.0003985359],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887663,0.00016854164,0.0002170117,0.00017587852,0.00033874623,0.00022317505],"domain_scores_gemma":[0.9971519,0.0011711734,0.000049686332,0.001105699,0.00035424563,0.00016727309],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040520233,0.00008026114,0.00013424068,0.000043461216,0.00026853234,0.000017173861,0.00047552545,0.00007136656,0.0000089493815],"category_scores_gemma":[0.0005598754,0.000040006955,0.00007750278,0.0002648091,0.0016331156,0.000028292356,0.00025488887,0.00021438026,0.000021882903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012552318,0.00035741462,0.000076540746,0.000018246581,0.00003733074,4.3255673e-7,0.000033888504,4.6673794e-9,0.96204674,0.021313135,0.0003185289,0.015672209],"study_design_scores_gemma":[0.000576967,0.00017805184,0.010856362,0.00011863472,0.000023747123,0.0000021692495,0.00007738564,0.00010348327,0.976833,0.0070696026,0.004086146,0.000074491974],"about_ca_topic_score_codex":0.000032936823,"about_ca_topic_score_gemma":0.0000014183876,"teacher_disagreement_score":0.020182664,"about_ca_system_score_codex":0.00003646599,"about_ca_system_score_gemma":0.000109034365,"threshold_uncertainty_score":0.60172826},"labels":[],"label_agreement":null},{"id":"W2556804481","doi":"10.1186/s12885-016-2906-9","title":"Autophagy is associated with chemoresistance in neuroblastoma","year":2016,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Ligue Contre le Cancer","keywords":"Autophagy; ATG5; Neuroblastoma; Cancer research; Dacarbazine; Chemotherapy; Vincristine; Gene knockdown; In vivo; Medicine; Doxorubicin; Programmed cell death; Cisplatin; Temozolomide; Cell culture; Biology; Cyclophosphamide; Apoptosis; Internal medicine; Glioma; Melanoma","score_opus":0.016687029135856474,"score_gpt":0.27715155116938817,"score_spread":0.2604645220335317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2556804481","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962265,0.0009004774,0.000083399,0.0008349926,0.00007013871,0.00017432669,0.00002186924,0.00007032291,0.0016179889],"genre_scores_gemma":[0.9878553,0.00012040979,0.000044036453,0.0020090088,0.000091511225,0.000074095435,0.000001778103,0.000026048443,0.009777811],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99921775,0.000019133702,0.0001277708,0.00022399482,0.00018837489,0.00022297293],"domain_scores_gemma":[0.99954414,0.00005111683,0.000059900212,0.00021127786,0.00004683659,0.00008672545],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00004773673,0.00011274164,0.00020002078,0.000049859485,0.00002060584,0.000005060896,0.000060638435,0.000053685537,0.001246682],"category_scores_gemma":[0.000035383448,0.00006736204,0.00004634984,0.0001926782,0.000060067207,0.00005592841,0.0000100932575,0.000060411934,0.00003698188],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0074445247,0.0011735662,0.8077247,0.00022854428,0.0005850201,0.0010521845,0.0010162793,0.000018941815,0.111130424,0.0007967288,0.035691135,0.03313794],"study_design_scores_gemma":[0.004930483,0.00013242537,0.93313384,0.0005696561,0.00004397841,0.000006162073,0.000007635448,0.000047031546,0.05759932,0.0001337192,0.0032557931,0.00013997921],"about_ca_topic_score_codex":0.000042683507,"about_ca_topic_score_gemma":0.00046095872,"teacher_disagreement_score":0.12540911,"about_ca_system_score_codex":0.0001686126,"about_ca_system_score_gemma":0.00024353123,"threshold_uncertainty_score":0.99966633},"labels":[],"label_agreement":null},{"id":"W2560066606","doi":"10.1158/1541-7786.mcr-16-0132","title":"Autophagy Inhibition Enhances Sunitinib Efficacy in Clear Cell Ovarian Carcinoma","year":2017,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Victoria; BC Cancer Agency","funders":"Canadian Institutes of Health Research; National Cancer Institute; Carraresi Foundation; BC Cancer Foundation; AstraZeneca","keywords":"Sunitinib; Autophagy; Cancer research; ATG5; Viability assay; Receptor tyrosine kinase; Programmed cell death; Biology; Cell; Cancer; Medicine; Kinase; Internal medicine; Apoptosis; Cell biology; Biochemistry","score_opus":0.0690901490990339,"score_gpt":0.4218686731623127,"score_spread":0.3527785240632788,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2560066606","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9785538,0.001993933,0.000027711147,0.0021229424,0.00010655948,0.0006360345,0.000011669515,0.00003466535,0.016512686],"genre_scores_gemma":[0.9976152,0.00033958652,0.000069700676,0.00033031357,0.00021000496,0.0001631795,0.00002193609,0.00004570246,0.0012043649],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99777645,0.00021578511,0.00022686234,0.00043743697,0.00073691545,0.0006065498],"domain_scores_gemma":[0.99854076,0.00004995218,0.00007315155,0.0008978707,0.00019921646,0.00023907326],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00063681684,0.00015522675,0.00026356147,0.00028619496,0.00037960004,0.0001282487,0.00029402692,0.00013506475,0.0007908133],"category_scores_gemma":[0.00014097807,0.00014912857,0.00010842299,0.00022513945,0.00029947318,0.00012905609,0.00014567093,0.0006084174,0.0001436424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014685721,0.0008824179,0.0046873163,0.00023848233,0.000060908533,0.0050086803,0.00078571576,0.000014133021,0.9698337,0.0018930178,0.0007603603,0.014366707],"study_design_scores_gemma":[0.0035069284,0.0002958995,0.20730694,0.00017193439,0.000015794021,0.000007485867,0.00008227614,0.00009744893,0.78565073,0.00040196403,0.002325534,0.00013707827],"about_ca_topic_score_codex":0.0022084045,"about_ca_topic_score_gemma":0.00010119367,"teacher_disagreement_score":0.20261963,"about_ca_system_score_codex":0.00019557597,"about_ca_system_score_gemma":0.0004984087,"threshold_uncertainty_score":0.86588514},"labels":[],"label_agreement":null},{"id":"W2560079349","doi":"10.1186/s13024-016-0141-0","title":"ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington’s disease models","year":2016,"lang":"en","type":"article","venue":"Molecular Neurodegeneration","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":161,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Institutes of Health; CHDI Foundation","keywords":"Autophagy; Phosphorylation; Molecular medicine; Neurology; Disease; ULK1; Medicine; Neuroscience; Cell biology; Biology; Internal medicine; Genetics; Protein kinase A; Cancer; Apoptosis","score_opus":0.011538604868929924,"score_gpt":0.23699490999142145,"score_spread":0.2254563051224915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2560079349","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913396,0.00070340506,0.0061569465,0.0011718118,0.000043232136,0.00045915175,0.000022430027,0.000049742866,0.000053668646],"genre_scores_gemma":[0.9989027,0.00013641293,0.00021729695,0.0005214425,0.000031475076,0.000032795702,0.0000444079,0.000029665036,0.00008383287],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99890506,0.00007193317,0.00029986657,0.0003195394,0.0002399921,0.00016360158],"domain_scores_gemma":[0.99938124,0.000026784715,0.00010189403,0.00026667854,0.00008764007,0.00013574323],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001063335,0.00014701301,0.00020021031,0.00013338104,0.00003087935,0.000011839256,0.00004269225,0.00006762244,0.0000429992],"category_scores_gemma":[0.000096226606,0.000114812974,0.00006505967,0.00014516604,0.000048801016,0.00016509395,0.000022004699,0.000052504594,0.0000052632176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025747294,0.00016285325,0.005333046,0.00004437244,0.00002112177,0.000037468497,0.0001788272,0.00011114782,0.98745215,0.000683779,0.000032023778,0.005685747],"study_design_scores_gemma":[0.0018102009,0.00013779945,0.07695461,0.00008171455,0.00004874046,0.0000022094746,0.000002691449,0.029686745,0.8890821,0.0020571216,0.00001866252,0.00011742714],"about_ca_topic_score_codex":0.000025337524,"about_ca_topic_score_gemma":0.0000031012416,"teacher_disagreement_score":0.09837007,"about_ca_system_score_codex":0.000031067528,"about_ca_system_score_gemma":0.00009087897,"threshold_uncertainty_score":0.46819374},"labels":[],"label_agreement":null},{"id":"W2560410271","doi":"10.1080/15548627.2016.1261319","title":"FYCO1 and autophagy control the integrity of the haploid male germ cell-specific RNP granules","year":2016,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Novo Nordisk Fonden","keywords":"Biology; Cell biology; Ribonucleoprotein; Piwi-interacting RNA; Autophagy; Somatic cell; Germline; Germ cell; RNA; Cytoplasm; Granule (geology); RNA-binding protein; Ribonucleoprotein particle; Genetics; RNA interference; Gene; Apoptosis","score_opus":0.010361237316188442,"score_gpt":0.22930445017439446,"score_spread":0.21894321285820603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2560410271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98036325,0.010666266,0.0005059517,0.0037882032,0.0004594172,0.0007216982,0.000072205825,0.000087231485,0.0033357593],"genre_scores_gemma":[0.99152744,0.0009554348,0.00006388681,0.0014679795,0.00024725593,0.000051147017,0.000002565331,0.00003790121,0.0056463876],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981944,0.00019985392,0.00043987232,0.0003755397,0.0004080181,0.00038234852],"domain_scores_gemma":[0.99809086,0.00045169893,0.00023458502,0.00094249856,0.00012631484,0.00015405058],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004024811,0.00027854188,0.00046498093,0.00006264447,0.00021279907,0.000024649755,0.00037631005,0.00016151322,0.0010260192],"category_scores_gemma":[0.000091047696,0.00011836758,0.0002818677,0.00018326979,0.0006837774,0.000103958155,0.00009507104,0.0003074392,0.00008566105],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021845829,0.0017851994,0.048215438,0.00042242324,0.0009516668,0.0003174528,0.0026942028,0.000004650492,0.7132318,0.05810449,0.03421728,0.13787085],"study_design_scores_gemma":[0.008583675,0.000378623,0.55466545,0.00024667525,0.00028648737,0.0002347831,0.00017665606,0.0001369225,0.37603787,0.0058808024,0.05303247,0.00033956787],"about_ca_topic_score_codex":0.000050339484,"about_ca_topic_score_gemma":0.0000049267314,"teacher_disagreement_score":0.50645006,"about_ca_system_score_codex":0.00005049883,"about_ca_system_score_gemma":0.00014977723,"threshold_uncertainty_score":0.99988717},"labels":[],"label_agreement":null},{"id":"W2560648000","doi":"10.1080/15548627.2016.1260808","title":"Autophagic homeostasis is required for the pluripotency of cancer stem cells","year":2016,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":139,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"","keywords":"Homeobox protein NANOG; SOX2; Biology; Cell biology; Nicotinamide phosphoribosyltransferase; Transcription factor; Autophagy; BECN1; Stem cell; Rex1; Cancer stem cell; Cellular differentiation; Cancer research; Induced pluripotent stem cell; Embryonic stem cell; NAD+ kinase; Biochemistry","score_opus":0.027871734099894695,"score_gpt":0.305634038905545,"score_spread":0.27776230480565034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2560648000","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93987775,0.042059615,0.002702091,0.010605287,0.0013233211,0.0019390717,0.00059110386,0.00021169207,0.00069009844],"genre_scores_gemma":[0.9814089,0.0032364575,0.00017545623,0.00194368,0.00029482343,0.00024738308,0.000002732952,0.000051635237,0.012638913],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984761,0.000033097116,0.00042456173,0.0003507172,0.00032322807,0.00039230104],"domain_scores_gemma":[0.9984241,0.00032221666,0.00021220841,0.00071066973,0.00018857387,0.00014219152],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00019277337,0.0002234972,0.00042390657,0.00008369159,0.00011575504,0.000010123636,0.00026429063,0.00012259778,0.0015492577],"category_scores_gemma":[0.00002017692,0.00011449273,0.00033957305,0.00020561209,0.00024150129,0.00010041315,0.00004325117,0.00007110688,0.000079563135],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00089122105,0.00034764342,0.0006265929,0.000290024,0.0011290838,0.00004087975,0.0011939601,0.0000040903387,0.28869343,0.0029840053,0.017114129,0.6866849],"study_design_scores_gemma":[0.0038331936,0.00034754397,0.011357368,0.00019307097,0.00033178175,0.0000075646735,0.000090526475,0.00018260977,0.93086225,0.0015403426,0.051064584,0.00018916231],"about_ca_topic_score_codex":0.00008107705,"about_ca_topic_score_gemma":0.0000041726444,"teacher_disagreement_score":0.6864958,"about_ca_system_score_codex":0.00008276077,"about_ca_system_score_gemma":0.00025926894,"threshold_uncertainty_score":0.9993635},"labels":[],"label_agreement":null},{"id":"W2561316863","doi":"10.15252/embj.201695063","title":"Fluorescence‐based ATG8 sensors monitor localization and function of LC3/GABARAP proteins","year":2016,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; Deutschen Konsortium für Translationale Krebsforschung; Fritz Thyssen Stiftung; Hessisches Ministerium für Wissenschaft und Kunst; Deutsche Forschungsgemeinschaft; Human Frontier Science Program","keywords":"Mitophagy; Autophagy; Cell biology; Mitochondrion; Chemistry; Biogenesis; Organelle; Function (biology); Fusion protein; Biology; Biochemistry; Gene","score_opus":0.016657521516748253,"score_gpt":0.2672893257425578,"score_spread":0.25063180422580955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2561316863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866426,0.0004080863,0.011052142,0.0013729113,0.00016011034,0.00021005802,0.0000031805455,0.000017867604,0.00013305481],"genre_scores_gemma":[0.99882483,0.0001755087,0.0001406268,0.0001856035,0.00039429805,0.0000042681772,9.873138e-7,0.00001208512,0.00026181183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993083,0.000078346,0.00018600695,0.00007770508,0.0002312423,0.0001184389],"domain_scores_gemma":[0.9994729,0.000041895437,0.00012937891,0.00014347179,0.000113459486,0.00009887997],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022991525,0.000079555786,0.00012686854,0.000059305148,0.00012042265,0.0000111759055,0.00004885807,0.000037519814,0.00023973557],"category_scores_gemma":[0.00004685232,0.000037283105,0.000060154918,0.00008226044,0.00011239503,0.00007351832,0.000007686515,0.00009732687,0.000011832924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006139458,0.00058894226,0.04567326,0.0001787978,0.0005617067,0.00013286949,0.0010158935,0.00017858899,0.71242404,0.0009726559,0.003535084,0.22859867],"study_design_scores_gemma":[0.01120503,0.0023626876,0.2967543,0.0014480394,0.0006144326,0.0005821118,0.00047483682,0.0051577166,0.6703055,0.0064570955,0.004304935,0.00033332082],"about_ca_topic_score_codex":0.0000034677287,"about_ca_topic_score_gemma":2.302709e-7,"teacher_disagreement_score":0.25108105,"about_ca_system_score_codex":0.000026293523,"about_ca_system_score_gemma":0.000071528055,"threshold_uncertainty_score":0.26249364},"labels":[],"label_agreement":null},{"id":"W2561754441","doi":"10.1074/jbc.m116.771584","title":"Regulation of ULK1 Expression and Autophagy by STAT1","year":2016,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital; Université de Montréal; McGill University Health Centre","funders":"National Cancer Institute; Fonds de Recherche du Québec - Santé; National Institutes of Health; Canada Research Chairs","keywords":"Autophagy; Cell biology; PI3K/AKT/mTOR pathway; STAT1; Biology; BAG3; Autophagy-related protein 13; Kinase; Chemistry; Protein kinase A; Phosphorylation; Signal transduction; Biochemistry; Apoptosis; Mitogen-activated protein kinase kinase","score_opus":0.015384806794158757,"score_gpt":0.2716769118870547,"score_spread":0.2562921050928959,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2561754441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974231,0.0016634414,0.00025486364,0.00028188582,0.000019572877,0.00002589873,0.000008946262,0.000005833013,0.00031643294],"genre_scores_gemma":[0.9986548,0.00047829188,0.00025185477,0.00006048042,0.000110347006,4.9340287e-7,0.0000027826234,0.0000031742354,0.0004378031],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99946976,0.000015119248,0.00025517243,0.00007221529,0.000114664035,0.000073070936],"domain_scores_gemma":[0.99944663,0.00006873891,0.00023132005,0.000074456795,0.00007223719,0.00010659833],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011293564,0.00006163572,0.00019541645,0.000009994532,0.000012779571,0.0000020091572,0.00004323063,0.0001089625,0.00053893944],"category_scores_gemma":[0.00010921558,0.000028394821,0.00006556459,0.000024835723,0.00009402364,0.000034996454,0.000014493882,0.00006726903,7.885399e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038690952,0.000087396984,0.0032454324,0.00002430114,0.000021578731,0.000011232643,0.000011894473,6.1495456e-8,0.9901709,0.0000044821845,0.00091254973,0.0051232693],"study_design_scores_gemma":[0.0012060199,0.00022076149,0.032204803,0.00015229468,0.000014874269,0.00008155344,0.00001483784,0.0000017558377,0.9638296,0.0007032992,0.0015335281,0.00003667052],"about_ca_topic_score_codex":1.7408532e-7,"about_ca_topic_score_gemma":2.0090871e-9,"teacher_disagreement_score":0.02895937,"about_ca_system_score_codex":0.000021582537,"about_ca_system_score_gemma":0.000036302063,"threshold_uncertainty_score":0.5901009},"labels":[],"label_agreement":null},{"id":"W2563516437","doi":"10.1016/j.neures.2016.12.004","title":"Ulk1 protects against ethanol-induced neuronal stress and cognition-related behavioral deficits","year":2016,"lang":"en","type":"article","venue":"Neuroscience Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"Congressionally Directed Medical Research Programs; National Center for Research Resources; Japan Society for the Promotion of Science; National Institutes of Health; Daiichi Sankyo Foundation of Life Science; Maryland Stem Cell Research Fund; Takeda Science Foundation; National Alliance for Research on Schizophrenia and Depression; Takeda Pharmaceutical Company; U.S. Department of Defense","keywords":"Autophagy; Neuroprotection; Prefrontal cortex; ULK1; Neuroscience; Ethanol; Psychology; Chemistry; Cell biology; Biology; Cognition; Biochemistry; Phosphorylation; Protein kinase A; Apoptosis","score_opus":0.14136806278285102,"score_gpt":0.41907523473522507,"score_spread":0.27770717195237404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2563516437","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964697,0.00007579455,0.00001159231,0.0014424137,0.00014334056,0.0008016953,0.00002683985,0.0000829109,0.00094572175],"genre_scores_gemma":[0.9985739,0.00019917084,0.000011480467,0.00032094336,0.00005454155,0.00008628438,0.0000034203047,0.00002447167,0.0007258074],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972394,0.00022586854,0.00019129591,0.0005843026,0.0011065386,0.00065257814],"domain_scores_gemma":[0.9988019,0.00016907939,0.000040330768,0.00032307208,0.00025109272,0.00041450883],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047497154,0.00014185288,0.00016567601,0.000278047,0.00034228363,0.00006510159,0.00021038028,0.000105835825,0.00006815954],"category_scores_gemma":[0.0004740521,0.00009481159,0.00004816993,0.000652537,0.00067122956,0.00021602496,0.00012944601,0.00045799048,0.00006625156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011330942,0.00030717044,0.0029792245,0.000025994827,0.0000026965486,0.0002527916,0.000069017755,2.266406e-7,0.96913695,0.00012485783,0.000034710825,0.026953056],"study_design_scores_gemma":[0.0025859475,0.001903282,0.24525361,0.00036440635,0.000014990017,0.00007687594,0.00005592073,0.00017407493,0.74854964,0.00054120243,0.00027572177,0.00020432331],"about_ca_topic_score_codex":0.000011800297,"about_ca_topic_score_gemma":0.0000019896647,"teacher_disagreement_score":0.24227437,"about_ca_system_score_codex":0.00003914824,"about_ca_system_score_gemma":0.00033412297,"threshold_uncertainty_score":0.38663045},"labels":[],"label_agreement":null},{"id":"W2565662820","doi":"10.1096/fasebj.30.1_supplement.764.3","title":"Parkin‐Mediated Mitophagy in Skeletal Muscle with Aging and Exercise","year":2016,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mitophagy; Parkin; Skeletal muscle; Mitochondrion; Endocrinology; Internal medicine; Sarcopenia; Autophagy; Chemistry; Ubiquitin ligase; PINK1; Cell biology; Ubiquitin; Biology; Biochemistry; Medicine; Apoptosis","score_opus":0.00944133318023548,"score_gpt":0.24105806291856047,"score_spread":0.23161672973832498,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2565662820","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946402,0.0031427355,0.000090421636,0.001624876,0.00007251881,0.00012440102,0.0000032072946,0.000018644849,0.0002829997],"genre_scores_gemma":[0.99761087,0.0013676103,0.000068321126,0.00037492893,0.00020896818,0.0000052586774,0.000001107033,0.000016478813,0.0003464861],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992583,0.000049297385,0.00015742588,0.00010862436,0.00019517464,0.00023121646],"domain_scores_gemma":[0.9994887,0.000086518965,0.000069891525,0.00015242795,0.000032677297,0.00016975806],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024274866,0.00010585247,0.00016846438,0.00008064688,0.00009293799,0.000020967784,0.000078742916,0.000033938923,0.00023827922],"category_scores_gemma":[0.000023749591,0.0000452823,0.00004195211,0.000106056876,0.0001221971,0.000100384445,0.000017547249,0.00019058389,0.000024441602],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011477936,0.00043587072,0.113439895,0.00005344374,0.0003467891,0.0032789349,0.0023930443,0.0000052034206,0.49729168,0.000114233124,0.00096296525,0.38053015],"study_design_scores_gemma":[0.01489449,0.00063127617,0.8804381,0.0017568731,0.00026742503,0.00227828,0.0007097391,0.00010430423,0.09418604,0.0013386734,0.003049314,0.00034549143],"about_ca_topic_score_codex":0.000008110691,"about_ca_topic_score_gemma":0.0000046319046,"teacher_disagreement_score":0.7669982,"about_ca_system_score_codex":0.000031811876,"about_ca_system_score_gemma":0.00007720115,"threshold_uncertainty_score":0.26089904},"labels":[],"label_agreement":null},{"id":"W2565738065","doi":"10.1158/1538-7445.am2015-395","title":"Abstract 395: Effect of pantoprazole to enhance activity of docetaxel against human tumor xenografts by inhibiting autophagy","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Autophagy; Docetaxel; Pantoprazole; Apoptosis; Chemistry; Pharmacology; Programmed cell death; Cancer research; Chemotherapy; Biology; Medicine; Internal medicine; Biochemistry","score_opus":0.060458474715807085,"score_gpt":0.46113869298917787,"score_spread":0.4006802182733708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2565738065","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99364823,0.0020644006,0.000009748612,0.00019277183,0.000082220606,0.00077882514,0.00006630045,0.000036897596,0.0031205767],"genre_scores_gemma":[0.99892825,0.00009495192,0.000019950152,0.000092103815,0.0002222044,0.0001639398,0.0000137040515,0.000036129913,0.0004287765],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976106,0.00018273327,0.00032067543,0.00035710077,0.0010006449,0.0005281977],"domain_scores_gemma":[0.9983509,0.00020197153,0.00013812541,0.00041020068,0.0004334337,0.00046534016],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016242432,0.00017356269,0.0005212767,0.00022100209,0.000091272355,0.000014961063,0.00022732388,0.000078943965,0.0001615306],"category_scores_gemma":[0.00031722226,0.00014446203,0.00011365071,0.0005309405,0.00023583551,0.00011443963,0.000111802765,0.00045400212,0.0000316564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010414016,0.00025104266,0.0017170683,0.00048011832,0.00008329382,0.000054332333,0.00041834006,0.000011741324,0.97036207,0.000011321488,0.0046380153,0.02093123],"study_design_scores_gemma":[0.0015154661,0.00100355,0.008987568,0.000521323,0.000015995269,0.0000018322676,0.00006866811,0.000014220172,0.986488,0.000028901086,0.0012406628,0.000113850554],"about_ca_topic_score_codex":0.00083569024,"about_ca_topic_score_gemma":0.000024087794,"teacher_disagreement_score":0.02081738,"about_ca_system_score_codex":0.00021836215,"about_ca_system_score_gemma":0.0004336789,"threshold_uncertainty_score":0.5890991},"labels":[],"label_agreement":null},{"id":"W2567335695","doi":"10.1016/j.bbamcr.2016.12.015","title":"Effect of acute and chronic autophagy deficiency on skeletal muscle apoptotic signaling, morphology, and function","year":2016,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Autophagy; Skeletal muscle; Cell biology; Myocyte; Glycolysis; Biology; Internal medicine; Endocrinology; Apoptosis; Chemistry; Biochemistry; Metabolism; Medicine","score_opus":0.013378318984422391,"score_gpt":0.3164511849748845,"score_spread":0.3030728659904621,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2567335695","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99667585,0.0011071432,0.00010307403,0.0005901409,0.000060050443,0.0007558479,0.00003008159,0.000050206454,0.00062761526],"genre_scores_gemma":[0.99858594,0.00080061675,0.000043443346,0.00013116424,0.000085110325,0.0000517509,0.000026961505,0.00005563842,0.00021934553],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972326,0.0005651028,0.00026959318,0.00068909023,0.000662421,0.0005811825],"domain_scores_gemma":[0.9985251,0.0003930348,0.00010423286,0.000576767,0.00012178625,0.00027907448],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007238149,0.0002954328,0.00042897635,0.0003245223,0.00014036706,0.000030655872,0.00018448518,0.00019621511,0.00007757399],"category_scores_gemma":[0.00006789348,0.00019821084,0.00017370548,0.00035936374,0.0007507652,0.00007697568,0.00016486071,0.00037256465,0.000048814738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007555352,0.0003173768,0.0000056969857,0.00026685785,0.0001588652,0.00008975355,0.000055113727,3.9964704e-7,0.9887369,0.00028420414,0.000093891314,0.0092354035],"study_design_scores_gemma":[0.0029437377,0.009983484,0.0035149085,0.00016571757,0.0002476624,0.00001377991,0.000009220905,0.00007237107,0.98253995,0.0002353243,0.000086612505,0.00018722194],"about_ca_topic_score_codex":0.000013982613,"about_ca_topic_score_gemma":2.001521e-7,"teacher_disagreement_score":0.009666108,"about_ca_system_score_codex":0.00008884979,"about_ca_system_score_gemma":0.00020142471,"threshold_uncertainty_score":0.80828035},"labels":[],"label_agreement":null},{"id":"W2568434110","doi":"10.1038/srep40351","title":"The autophagy elongation complex (ATG5-12/16L1) positively regulates HCV replication and is required for wild-type membranous web formation","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"ATG5; Autophagy; Viral replication; Cell biology; Virology; Biology; Hepatitis C virus; Chemistry; Virus; Biochemistry; Apoptosis","score_opus":0.039848858028790186,"score_gpt":0.32160939263662675,"score_spread":0.28176053460783657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2568434110","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99114126,0.00050687534,0.00026866494,0.0030789843,0.0017336354,0.0013913197,0.0000108941485,0.00009749892,0.0017708523],"genre_scores_gemma":[0.9924386,0.000076230375,0.0004177846,0.0001963666,0.00012485159,0.00006808007,0.00031088202,0.000019184974,0.006347982],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99823964,0.0000328026,0.0004871496,0.0006064643,0.00038314497,0.00025082738],"domain_scores_gemma":[0.9967305,0.000059928756,0.0007430716,0.0018492689,0.00049582374,0.00012140793],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0014427094,0.00014287408,0.00020197558,0.00008126859,0.002461785,0.0005827478,0.00013990059,0.00008605984,0.000029390374],"category_scores_gemma":[0.00051596656,0.000104463754,0.00009383626,0.00010076764,0.00041822143,0.0005493989,0.00004811362,0.00006254852,0.0000089455525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007368591,0.00019013448,0.0034911744,0.00021229136,0.00019902682,0.00009625279,0.0020977384,0.0000056099902,0.8463461,0.00158679,0.052940838,0.09209718],"study_design_scores_gemma":[0.0018273562,0.0003105602,0.25047046,0.00019715888,0.00026224914,0.0006248375,0.00017935337,0.015697911,0.5495609,0.03236869,0.14814484,0.00035567247],"about_ca_topic_score_codex":0.000015982288,"about_ca_topic_score_gemma":0.000013925772,"teacher_disagreement_score":0.2967852,"about_ca_system_score_codex":0.00006227621,"about_ca_system_score_gemma":0.00016862898,"threshold_uncertainty_score":0.9988369},"labels":[],"label_agreement":null},{"id":"W2570093446","doi":"10.1093/hmg/ddx001","title":"Cyclodextrin has conflicting actions on autophagy flux <i>in vivo</i> in brains of normal and Alzheimer model mice","year":2017,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; Alzheimer's Association; National Institute of Neurological Disorders and Stroke; National Institute on Aging; University of Alberta","keywords":"Autophagy; Lysosome; Biology; Autophagosome; Cathepsin B; Cell biology; Cathepsin D; Sequestosome 1; Neurodegeneration; Proteostasis; Cathepsin; Tauopathy; Amyloid precursor protein; Population; Biochemistry; Alzheimer's disease; Internal medicine; Medicine; Enzyme","score_opus":0.06878221894323253,"score_gpt":0.35248586765820505,"score_spread":0.28370364871497256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2570093446","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99164724,0.0011566915,0.00034535755,0.00014146602,0.000033165925,0.00026830984,0.000011693513,0.00001426925,0.0063818325],"genre_scores_gemma":[0.99831104,0.00008344519,0.0007567346,0.0005233802,0.000032956188,0.00001330907,0.000007778986,0.000030221054,0.000241141],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999062,0.0000306489,0.00026698658,0.0002436842,0.00017537562,0.00022130786],"domain_scores_gemma":[0.99921525,0.0000175873,0.00012560798,0.00050567376,0.00003709346,0.00009879573],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001053892,0.00014997157,0.00024804397,0.00013469964,0.0001537668,0.000031462383,0.000137784,0.00010531828,0.000043523876],"category_scores_gemma":[0.000024588462,0.00016187156,0.000066833585,0.00004389384,0.00016192363,0.000038096543,0.00006014981,0.00018537424,0.0000033984238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001113987,0.00037303442,0.0051758955,0.000036676567,0.00012356845,0.0002172443,0.0009412678,0.004197998,0.9849884,0.0019086548,0.000062932064,0.001862928],"study_design_scores_gemma":[0.0047927513,0.00032719492,0.16689095,0.00018579265,0.00019264517,0.000023003258,0.0000804635,0.02876892,0.7963768,0.0012325934,0.0008277225,0.0003011216],"about_ca_topic_score_codex":0.00007979668,"about_ca_topic_score_gemma":0.00006914806,"teacher_disagreement_score":0.18861155,"about_ca_system_score_codex":0.000019633912,"about_ca_system_score_gemma":0.00007489157,"threshold_uncertainty_score":0.66009307},"labels":[],"label_agreement":null},{"id":"W2579228630","doi":"10.1016/j.cjca.2017.01.002","title":"Autophagy, Metabolic Disease, and Pathogenesis of Heart Dysfunction","year":2017,"lang":"en","type":"review","venue":"Canadian Journal of Cardiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Medicine; Pyroptosis; Diabetic cardiomyopathy; Heart failure; Diabetes mellitus; Disease; Pathogenesis; Mitophagy; Cardiomyopathy; Dyslipidemia; Bioinformatics; Inflammasome; Immunology; Inflammation; Internal medicine; Endocrinology; Biology; Apoptosis","score_opus":0.0641335544071862,"score_gpt":0.3387269084494628,"score_spread":0.2745933540422766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2579228630","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00037287976,0.9977056,0.00003838913,0.00009170764,0.00085336546,0.00025598324,0.00016158567,0.0000033288031,0.0005171803],"genre_scores_gemma":[0.004785771,0.9931721,0.000038823146,0.000079654434,0.001658739,0.0000086080145,0.000028583074,0.00003637508,0.00019132465],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99857575,0.00023685073,0.00061899726,0.00018143273,0.00012604459,0.00026090644],"domain_scores_gemma":[0.99745816,0.000066884015,0.0006494352,0.00044851954,0.00020889568,0.0011681062],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036924088,0.00024990478,0.0029117244,0.0005314881,0.00009458404,0.000014513031,0.00017452,0.0002776001,0.000040673378],"category_scores_gemma":[0.00024391488,0.00018950042,0.0010405506,0.000077675315,0.00028763647,0.000054733573,0.00001274303,0.00030215617,0.0000069245757],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055252982,0.0000042378238,0.0009462548,0.0029896018,0.0022287222,0.001000956,0.000013292738,0.0000025417507,0.000003562324,0.00017855385,0.0038082427,0.98876876],"study_design_scores_gemma":[0.0004088973,0.00014003375,0.020274533,0.0021875212,0.005690657,0.0017522712,0.000003806362,2.8465908e-7,0.0000013674256,0.00009125013,0.9693257,0.00012365947],"about_ca_topic_score_codex":0.00012762885,"about_ca_topic_score_gemma":0.00003414325,"teacher_disagreement_score":0.98864514,"about_ca_system_score_codex":0.00007055261,"about_ca_system_score_gemma":0.005285618,"threshold_uncertainty_score":0.9376459},"labels":[],"label_agreement":null},{"id":"W2583138401","doi":"10.18632/oncotarget.14976","title":"EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells","year":2017,"lang":"en","type":"article","venue":"Oncotarget","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Children's Hospital Research Institute of Manitoba; Research Institute in Oncology and Hematology; University of Manitoba; CancerCare Manitoba","funders":"Instituto de Salud Carlos III; Asociación Pablo Ugarte; Austrian Science Fund; European Commission; Research Manitoba; CancerCare Manitoba Foundation; Heart and Stroke Foundation of Canada","keywords":"Medicine; Family medicine; Gerontology","score_opus":0.020684761117914178,"score_gpt":0.31360199432212926,"score_spread":0.2929172332042151,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2583138401","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883883,0.00008040943,0.0002823603,0.0017608091,0.00028149105,0.00036279988,0.000023162278,0.000055104672,0.008765551],"genre_scores_gemma":[0.9952649,0.000028673529,0.00057662587,0.0029675853,0.00027336567,0.000012945022,0.000033425804,0.00002499931,0.0008174788],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99890596,0.00005681134,0.00020394589,0.00029106232,0.00022778306,0.0003144696],"domain_scores_gemma":[0.9990148,0.000041014042,0.00009151957,0.00056334445,0.0000577205,0.00023157854],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003504067,0.00016085182,0.00031261836,0.000112695336,0.00017806405,0.000056923764,0.00005727462,0.00009861966,0.00022014692],"category_scores_gemma":[0.00007730241,0.00015443203,0.00009500529,0.00006637748,0.00006231523,0.00018725617,0.00006746659,0.00018684228,0.00033525666],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011031013,0.0007428676,0.19367576,0.0001223281,0.000109385626,0.0047031394,0.0022450995,0.00005338168,0.78050554,0.00072346715,0.009200847,0.0068150763],"study_design_scores_gemma":[0.0034780703,0.00026372148,0.6765376,0.00034948395,0.000041122865,0.000043601478,0.00014100237,0.0005348209,0.30187768,0.00056262314,0.015847173,0.0003231487],"about_ca_topic_score_codex":0.00025803316,"about_ca_topic_score_gemma":0.000066124296,"teacher_disagreement_score":0.4828618,"about_ca_system_score_codex":0.000115888055,"about_ca_system_score_gemma":0.00008648801,"threshold_uncertainty_score":0.6297555},"labels":[],"label_agreement":null},{"id":"W2590621618","doi":"10.1080/15548627.2017.1290751","title":"New frontiers in the treatment of colorectal cancer: Autophagy and the unfolded protein response as promising targets","year":2017,"lang":"en","type":"review","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":155,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Manitoba","funders":"National Institute for Genetic Engineering and Biotechnology; Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"Autophagy; Unfolded protein response; Biology; Colorectal cancer; Cancer; Malignancy; Cancer research; Disease; Bioinformatics; Gene; Genetics; Apoptosis; Medicine; Internal medicine","score_opus":0.04179167769608115,"score_gpt":0.3749443467288048,"score_spread":0.3331526690327236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2590621618","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.02006962,0.97182256,0.000009578167,0.0004999761,0.00038328426,0.0067746905,0.000044983506,0.000044334065,0.00035095832],"genre_scores_gemma":[0.002819277,0.99152964,0.00035724955,0.00011327849,0.00026766228,0.001395479,0.000037167665,0.000078919875,0.0034013458],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99669874,0.0009898244,0.0008251677,0.00057787367,0.00044118875,0.00046718435],"domain_scores_gemma":[0.9974855,0.0004391016,0.00080652296,0.0010370212,0.000051879335,0.00017995852],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00086766726,0.0006479776,0.002765887,0.00024400828,0.0002463925,0.00008027957,0.00054448296,0.00037606928,0.00011381888],"category_scores_gemma":[0.00022424245,0.0003172817,0.00071332126,0.00026014418,0.0004831757,0.000084695836,0.00005033631,0.00036252904,0.0000138184405],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004273088,0.00029494448,0.000009956579,0.0016968921,0.00095759076,0.0004614593,0.0022751228,2.7974258e-7,0.000027249474,0.00030260455,0.0005569125,0.9891439],"study_design_scores_gemma":[0.009874468,0.0014009514,0.00080250896,0.0063930275,0.002344461,0.0002016973,0.000102173224,0.000038652463,0.0009833751,0.0011521348,0.9763286,0.00037795134],"about_ca_topic_score_codex":0.00096374325,"about_ca_topic_score_gemma":0.000023729477,"teacher_disagreement_score":0.98876595,"about_ca_system_score_codex":0.00034668334,"about_ca_system_score_gemma":0.002646691,"threshold_uncertainty_score":0.99992794},"labels":[],"label_agreement":null},{"id":"W2591733180","doi":"10.1016/j.freeradbiomed.2016.10.241","title":"Aggravation of Oxidative Stress after Thioredoxin Reductase Deficiency Interrupts Starvation-Induced Autophagy through Oxidative Modification of Lysosomal Cathepsins","year":2016,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autophagy; Cell biology; Oxidative stress; Programmed cell death; Thioredoxin reductase; Thioredoxin; Cathepsin; Lysosome; Chemistry; Proteasome; Sequestosome 1; Biology; Biochemistry; Apoptosis; Enzyme","score_opus":0.032712277474911094,"score_gpt":0.333869120664877,"score_spread":0.30115684318996594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2591733180","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883013,0.002172488,0.005131056,0.0032972337,0.00016290322,0.0004073404,0.00017098656,0.000028799119,0.00032794182],"genre_scores_gemma":[0.99754936,0.0007863595,0.00092560437,0.00029290342,0.00016163565,0.00004123258,0.00016212808,0.000012157375,0.00006860561],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99851525,0.0001482891,0.0005712786,0.0003502548,0.00020238878,0.00021251284],"domain_scores_gemma":[0.99862444,0.00027177262,0.00034303576,0.00041093284,0.00022115263,0.00012866895],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024902466,0.00019137804,0.0005083752,0.0001523652,0.00004810381,0.0000011803922,0.00014051162,0.00022721024,0.00033150156],"category_scores_gemma":[0.0007832684,0.000109793174,0.000063696636,0.00022387203,0.0013538639,0.00011512577,0.000041857635,0.00013629902,0.0000033463841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013383714,0.00046409646,0.007353393,0.000095195,0.00015981286,0.000011806304,0.0032286372,1.281886e-7,0.9429871,0.028686281,0.0001467579,0.015528442],"study_design_scores_gemma":[0.0062300996,0.0032909175,0.1489426,0.0008872543,0.00027444382,0.000024485498,0.0006928909,0.000028959363,0.80624205,0.032945324,0.00025484603,0.00018614386],"about_ca_topic_score_codex":0.00013188958,"about_ca_topic_score_gemma":0.000008380223,"teacher_disagreement_score":0.14158921,"about_ca_system_score_codex":0.000042304102,"about_ca_system_score_gemma":0.00013062546,"threshold_uncertainty_score":0.49883676},"labels":[],"label_agreement":null},{"id":"W2592922319","doi":"10.1073/pnas.1615015114","title":"Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cells","year":2017,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique; Université du Québec à Montréal","funders":"National Cancer Institute","keywords":"Autophagy; Mammary gland; Breast cancer; Endocrinology; Internal medicine; Cancer; Receptor; Cancer research; Biology; Cell biology; Medicine; Apoptosis; Biochemistry","score_opus":0.021510493106574158,"score_gpt":0.3084268197629552,"score_spread":0.28691632665638106,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2592922319","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868609,0.00031518945,3.2921005e-8,0.011184586,0.000020966727,0.00015959221,0.000015218438,0.0000027806493,0.0014407655],"genre_scores_gemma":[0.9989575,0.0002245828,0.00013794664,0.00040327923,0.00011085596,0.000013299553,9.956999e-8,0.0000022808094,0.00015012453],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989548,0.0000062038985,0.00019269611,0.00015892756,0.0005637374,0.00012366848],"domain_scores_gemma":[0.999595,0.000053844476,0.00023661736,0.000014831815,0.000073121286,0.000026569463],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00092207803,0.0000710932,0.00013411025,0.00010398435,0.0001648074,0.00003409806,0.0005754513,0.000059585785,0.000018620884],"category_scores_gemma":[0.00007919373,0.00003904422,0.000033701992,0.00019230215,0.00076086377,0.0004240556,0.00008537112,0.000143821,4.019012e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003141673,0.00022290653,0.3892521,0.00022429581,0.000030361964,3.2647276e-7,0.0013727038,0.000012213559,0.59458,0.008403927,0.0014244072,0.004162588],"study_design_scores_gemma":[0.00045306925,0.000023208273,0.84270734,0.00016516748,0.0000072410144,0.00001929267,0.00011600343,0.00027418172,0.15229459,0.00384103,0.00005963515,0.000039230345],"about_ca_topic_score_codex":0.00005160984,"about_ca_topic_score_gemma":8.315177e-7,"teacher_disagreement_score":0.45345527,"about_ca_system_score_codex":0.000022484743,"about_ca_system_score_gemma":0.000050159444,"threshold_uncertainty_score":0.28034344},"labels":[],"label_agreement":null},{"id":"W2593462505","doi":"10.1038/ncomms14697","title":"Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Parkinson Society Canada; McGill University; Parkinson's Disease Foundation; Michael J. Fox Foundation for Parkinson's Research","keywords":"Parkin; Mitophagy; Ubiquitin ligase; PINK1; Ubiquitin; Phosphorylation; Cell biology; Mutagenesis; Mitochondrion; Autophagy; Mutation; Chemistry; Biology; Biochemistry; Gene; Parkinson's disease; Apoptosis","score_opus":0.04140317047973977,"score_gpt":0.37028774338336506,"score_spread":0.32888457290362527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2593462505","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9773744,0.0017794669,0.00040830186,0.011581963,0.00014522468,0.0005910959,0.00008376457,0.000075262236,0.007960522],"genre_scores_gemma":[0.99138117,0.00034520312,0.007037175,0.00077734527,0.00007237795,0.000023973527,0.00012127381,0.00001772282,0.00022376276],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99920875,0.00008979381,0.0002334858,0.00014352817,0.00020742325,0.000117039046],"domain_scores_gemma":[0.9959883,0.00013230911,0.00026091587,0.0033444087,0.00018762019,0.000086415246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014591074,0.00010619099,0.00022971624,0.0000827328,0.00043263403,0.000022241984,0.0008500429,0.00028457862,0.00010766318],"category_scores_gemma":[0.0004925775,0.00009142799,0.00010562888,0.000081623664,0.00018068057,0.00009844083,0.00019960405,0.000567776,0.00000441509],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002196287,0.0005500629,0.00931552,0.000087840825,0.00051742786,0.0000066395237,0.00055777066,0.0000016691674,0.5245139,0.44818136,0.0037786758,0.012269513],"study_design_scores_gemma":[0.0021906917,0.00012539265,0.6014059,0.0002454832,0.00032451822,0.00003191823,0.00005768826,0.00053413183,0.31704533,0.06695373,0.010825779,0.00025941987],"about_ca_topic_score_codex":0.00002345005,"about_ca_topic_score_gemma":0.00001942207,"teacher_disagreement_score":0.59209037,"about_ca_system_score_codex":0.000034320237,"about_ca_system_score_gemma":0.00009771261,"threshold_uncertainty_score":0.3728325},"labels":[],"label_agreement":null},{"id":"W2595270459","doi":"10.1016/j.jtcvs.2017.02.058","title":"Endothelial-specific deletion of autophagy-related 7 (ATG7) attenuates arterial thrombosis in mice","year":2017,"lang":"en","type":"article","venue":"Journal of Thoracic and Cardiovascular Surgery","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"National Institutes of Health; University of Toronto; Heart and Stroke Foundation of Canada","keywords":"Thrombosis; Medicine; Autophagy; Tissue factor; Umbilical vein; Tumor necrosis factor alpha; Endothelial stem cell; Endothelial dysfunction; Pathology; Apoptosis; Internal medicine; Biology; In vitro; Biochemistry","score_opus":0.027730451731267102,"score_gpt":0.29920860030005814,"score_spread":0.27147814856879104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2595270459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97087073,0.0276513,0.00019480167,0.00016952622,0.0007583113,0.00012254932,0.0000075648472,0.000008527898,0.00021668331],"genre_scores_gemma":[0.9861373,0.013251373,0.00012801778,0.000034145676,0.0003883704,0.00000276287,0.000003565903,0.000022303226,0.00003217085],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9982783,0.00018018764,0.0006988858,0.00017610285,0.00047270427,0.00019378409],"domain_scores_gemma":[0.99856704,0.00011266876,0.0005355749,0.0004659604,0.00019059917,0.0001281287],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017683926,0.00016260467,0.001088138,0.00024991832,0.000103417406,0.000042788317,0.00012514924,0.0001418125,0.000072698145],"category_scores_gemma":[0.00014909489,0.00013156042,0.0012599315,0.00008985613,0.00016087669,0.00025849356,0.000031321266,0.00022485618,0.0000053259305],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006296899,0.0012063611,0.12220963,0.0010092254,0.015156697,0.003895605,0.0014596399,0.00015176585,0.17078954,0.0001534471,0.0023068013,0.6753644],"study_design_scores_gemma":[0.0029891916,0.00022294221,0.87392116,0.0015551655,0.0015220281,0.0012260429,0.00027502276,0.00006326079,0.11162102,0.0007484238,0.005512119,0.000343601],"about_ca_topic_score_codex":0.000030781142,"about_ca_topic_score_gemma":6.644023e-7,"teacher_disagreement_score":0.75171155,"about_ca_system_score_codex":0.000032898628,"about_ca_system_score_gemma":0.00011806429,"threshold_uncertainty_score":0.5364878},"labels":[],"label_agreement":null},{"id":"W2599444544","doi":"10.1200/jco.2017.35.6_suppl.450","title":"Combined inhibition of autophagy with mTOR inhibitor to enhance cell death in renal cell carcinoma.","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Autophagy; PI3K/AKT/mTOR pathway; Clonogenic assay; Programmed cell death; Protein kinase B; Cancer research; Cell biology; Autophagosome; Lysosome; Biology; Viability assay; RPTOR; Cancer cell; Cell; Signal transduction; Cancer; Apoptosis; Biochemistry","score_opus":0.0554562812717667,"score_gpt":0.4235569135971827,"score_spread":0.368100632325416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2599444544","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99249846,0.00018199284,0.00017601656,0.0021094163,0.00054010324,0.00026181308,0.0000044220933,0.0000052731907,0.0042225197],"genre_scores_gemma":[0.994548,0.0000974496,0.0025769158,0.0014070367,0.00080051634,0.000005298656,0.000001849955,0.0000191306,0.00054378825],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99719673,0.00021395719,0.0017822839,0.0002111586,0.00036050167,0.00023533743],"domain_scores_gemma":[0.99613583,0.00048127992,0.0021988535,0.0003934257,0.00037952344,0.00041111384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014606459,0.00015235646,0.0012985066,0.00015657535,0.000054950982,0.000010371021,0.00021758337,0.00030307137,0.00010763769],"category_scores_gemma":[0.0005450601,0.00010755496,0.00028047562,0.000075984244,0.00018471021,0.00014784618,0.000060180562,0.0007103181,0.000020872498],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.07396888,0.017999453,0.7051378,0.00035664372,0.00031790344,0.009732393,0.0008546627,0.000077492456,0.15531053,0.00018342288,0.0057320567,0.030328758],"study_design_scores_gemma":[0.013080166,0.027062561,0.71486187,0.00023811545,0.00018929364,0.000040242554,0.00004191806,0.000031003634,0.24186146,0.00023351656,0.0022444923,0.00011535679],"about_ca_topic_score_codex":0.000041254872,"about_ca_topic_score_gemma":0.000028800045,"teacher_disagreement_score":0.08655095,"about_ca_system_score_codex":0.00011322982,"about_ca_system_score_gemma":0.0014722816,"threshold_uncertainty_score":0.4385964},"labels":[],"label_agreement":null},{"id":"W2603206028","doi":"10.1007/s00204-017-1942-9","title":"Initial autophagic protection switches to disruption of autophagic flux by lysosomal instability during cadmium stress accrual in renal NRK-52E cells","year":2017,"lang":"en","type":"article","venue":"Archives of Toxicology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Consejo Nacional de Ciencia y Tecnología; Deutsche Forschungsgemeinschaft; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Max Kade Foundation","keywords":"Autophagy; Cell biology; Flux (metallurgy); Accrual; Instability; Genome instability; Stress (linguistics); Chemistry; Biology; DNA damage; Apoptosis; Business; Mechanics; Physics; Biochemistry","score_opus":0.020670553129812426,"score_gpt":0.311408152488714,"score_spread":0.2907375993589016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2603206028","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99681646,0.000095623254,0.00017033043,0.00049172784,0.00023338675,0.0009203589,0.000101613194,0.00003623462,0.001134253],"genre_scores_gemma":[0.9991193,0.000016606926,0.00031170162,0.000060001807,0.00013748358,0.00009095965,0.000025403266,0.000021757425,0.00021679635],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982865,0.0001515002,0.0005707999,0.00041698344,0.00021214911,0.0003620892],"domain_scores_gemma":[0.9987121,0.00008726022,0.00036495176,0.00062021246,0.000036617195,0.00017883051],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016135423,0.00021042966,0.0005491151,0.00025207736,0.00014490396,0.000013040209,0.000305066,0.00016007645,0.00013970188],"category_scores_gemma":[0.00019583335,0.00019956882,0.00015143896,0.0000761998,0.00044059558,0.00016206453,0.00018954968,0.000292849,0.000009330316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025621336,0.0010238749,0.016724922,0.0002893643,0.00008436189,0.000054405213,0.001381347,0.00007308891,0.9707838,0.000104285624,0.000009527219,0.006908882],"study_design_scores_gemma":[0.0017617049,0.00071025186,0.44961855,0.00009053659,0.00002825108,0.000011565776,0.000072367235,0.00016707258,0.5468725,0.0005528748,0.000022969753,0.000091342015],"about_ca_topic_score_codex":0.0001916044,"about_ca_topic_score_gemma":0.00013352801,"teacher_disagreement_score":0.43289363,"about_ca_system_score_codex":0.000061965184,"about_ca_system_score_gemma":0.00017937136,"threshold_uncertainty_score":0.81381804},"labels":[],"label_agreement":null},{"id":"W2603524882","doi":"10.3390/cancers9040027","title":"EGFR Family Members’ Regulation of Autophagy Is at a Crossroads of Cell Survival and Death in Cancer","year":2017,"lang":"en","type":"review","venue":"Cancers","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"CancerCare Manitoba Foundation","keywords":"Autophagy; Cancer; Programmed cell death; Cell survival; Medicine; Cancer research; Oncology; Biology; Gerontology; Internal medicine; Apoptosis; Genetics","score_opus":0.1071444179156218,"score_gpt":0.40549696025517085,"score_spread":0.29835254233954905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2603524882","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03240974,0.96302694,0.0000013309582,0.000008450624,0.00032156202,0.000591795,0.0001977816,0.000009946099,0.0034324483],"genre_scores_gemma":[0.011215203,0.98381853,0.000027146534,0.000043601565,0.00011299429,0.00007519596,0.000049330712,0.000043095934,0.004614904],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986143,0.000052540898,0.00052968826,0.00034283524,0.00025239514,0.0002081998],"domain_scores_gemma":[0.9985411,0.000053554693,0.0006858023,0.0005310999,0.00007799526,0.00011043383],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001612328,0.0002762464,0.0016684219,0.00015190788,0.000043635715,0.00000684349,0.00014750476,0.00027503454,0.000338655],"category_scores_gemma":[0.00001558528,0.00021092316,0.0002817719,0.00012261375,0.0001689917,0.000050383325,0.000052477426,0.00016346177,0.0000025985262],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047926695,0.00008981642,0.0024123213,0.065414876,0.00086396124,0.00006121526,0.0013724759,0.000029201015,0.0004523114,0.00012261381,0.0018719538,0.92683],"study_design_scores_gemma":[0.0025908279,0.0001536118,0.014551704,0.017317174,0.0013472065,0.0000063595944,0.00003799653,0.000076820375,0.0013154059,0.000047080684,0.9622098,0.00034596492],"about_ca_topic_score_codex":0.0024539328,"about_ca_topic_score_gemma":0.00014458653,"teacher_disagreement_score":0.9603379,"about_ca_system_score_codex":0.001219667,"about_ca_system_score_gemma":0.001970184,"threshold_uncertainty_score":0.8601197},"labels":[],"label_agreement":null},{"id":"W2603793890","doi":"10.3389/fimmu.2017.00355","title":"Increased Autophagy-Related 5 Gene Expression Is Associated with Collagen Expression in the Airways of Refractory Asthmatics","year":2017,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Chicoutimi; McGill University; Christie (Canada)","funders":"Genentech; Canada Research Chairs","keywords":"ATG5; Asthma; Autophagy; Pathogenesis; Medicine; Fibrosis; Pulmonary fibrosis; Type I collagen; Alpha (finance); Gene expression; Immunology; Pathology; Gene; Biology; Apoptosis","score_opus":0.01043432376048755,"score_gpt":0.25228682724709467,"score_spread":0.2418525034866071,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2603793890","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99318814,0.0042401594,0.00032141354,0.00020132624,0.00034801822,0.0005260536,0.000019818683,0.000030486157,0.0011245734],"genre_scores_gemma":[0.9969986,0.00040654102,0.0019143308,0.0002133951,0.000020778456,0.00005070749,0.00005819276,0.000028188877,0.00030926123],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983758,0.00032197082,0.00045756795,0.00026586594,0.00026571832,0.00031311534],"domain_scores_gemma":[0.9982369,0.000100554265,0.000522901,0.0010199309,0.0000745509,0.000045150893],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045257053,0.00020114618,0.0005723729,0.0002266745,0.00017332844,0.000015184077,0.0004863074,0.00036833744,0.000103390434],"category_scores_gemma":[0.00032842238,0.00013429014,0.00007807961,0.00017196075,0.00038911842,0.00013402321,0.00008149364,0.00032822049,0.0000048288343],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005782313,0.0030230305,0.23704726,0.0001135347,0.0007117658,0.0010830865,0.014003535,0.00002871523,0.72048676,0.000111833855,0.011039518,0.0065686475],"study_design_scores_gemma":[0.010328871,0.00077393145,0.6653364,0.00080265355,0.00009257059,0.000024597095,0.0014376277,0.0003807036,0.31841138,0.0013479481,0.00083212694,0.0002312263],"about_ca_topic_score_codex":0.00007007531,"about_ca_topic_score_gemma":0.000007687664,"teacher_disagreement_score":0.4282891,"about_ca_system_score_codex":0.00013590732,"about_ca_system_score_gemma":0.00018090325,"threshold_uncertainty_score":0.5476193},"labels":[],"label_agreement":null},{"id":"W2604986769","doi":"10.1007/s00280-017-3298-5","title":"Up-regulation of autophagy is a mechanism of resistance to chemotherapy and can be inhibited by pantoprazole to increase drug sensitivity","year":2017,"lang":"en","type":"article","venue":"Cancer Chemotherapy and Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; Prostate Cancer Canada","keywords":"Autophagy; Pantoprazole; Drug resistance; Pharmacology; Cancer research; Chemotherapy; Programmed cell death; Biology; Apoptosis; Chemistry; Biochemistry","score_opus":0.013776681150835128,"score_gpt":0.3230400342287358,"score_spread":0.30926335307790065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2604986769","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9805863,0.0012123688,0.00016920517,0.016643211,0.00017645789,0.0007335252,0.00030360895,0.000026125837,0.00014922618],"genre_scores_gemma":[0.97325516,0.0019571276,0.0002019031,0.022576055,0.00013868789,0.00006100431,0.00001383503,0.000034644614,0.001761574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988082,0.00007072951,0.00029128502,0.00039743824,0.00017492278,0.00025742356],"domain_scores_gemma":[0.99885625,0.000064763764,0.00026088225,0.00032925745,0.00017761887,0.00031125147],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025246255,0.00022904482,0.0005563284,0.000101594844,0.00015693223,0.000013359818,0.00009978931,0.00011782828,0.00054695946],"category_scores_gemma":[0.000016540129,0.00022042784,0.000059708647,0.00012780988,0.00020757734,0.00007746055,0.00004200953,0.00011563573,6.3856317e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003749928,0.00014947102,0.0012515603,0.00017996972,0.0002675587,0.00000755512,0.0038290145,0.0000011389437,0.96148765,0.0001443231,0.016429989,0.012501847],"study_design_scores_gemma":[0.0059163203,0.0001910481,0.016215913,0.000096577816,0.00010681119,0.0000064143856,0.00006557953,0.00017376791,0.96468407,0.0003489031,0.012003182,0.00019140072],"about_ca_topic_score_codex":0.0007328063,"about_ca_topic_score_gemma":0.000117783566,"teacher_disagreement_score":0.014964352,"about_ca_system_score_codex":0.00005651338,"about_ca_system_score_gemma":0.00014178752,"threshold_uncertainty_score":0.89887863},"labels":[],"label_agreement":null},{"id":"W2606060101","doi":"10.1161/atvbaha.116.308916","title":"microRNA-33 Regulates Macrophage Autophagy in Atherosclerosis","year":2017,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":217,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; University of Ottawa","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"microRNA; Autophagy; Macrophage; Cell biology; Biology; Medicine; Cancer research; Apoptosis; Genetics; Gene; In vitro","score_opus":0.039894206902935755,"score_gpt":0.3232626760509325,"score_spread":0.28336846914799674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2606060101","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99759215,0.00033637,0.00003751616,0.00083301525,0.00023401328,0.00039429418,0.00003587252,0.00007252111,0.0004642526],"genre_scores_gemma":[0.9911216,0.006941388,0.00047955106,0.0011442867,0.00012952654,0.000067336405,0.000031104973,0.000049174803,0.000036040314],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981319,0.00011090741,0.00041491128,0.0006710512,0.0001255167,0.0005457299],"domain_scores_gemma":[0.99832964,0.000039262108,0.00019680407,0.0011536345,0.000050913393,0.00022977268],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003245291,0.0003434812,0.00075573655,0.00013406585,0.00047732744,0.00012729572,0.00030369367,0.0003178022,0.00028284808],"category_scores_gemma":[0.000053088155,0.00029124704,0.00028999674,0.00008264503,0.00055530557,0.00017800229,0.00019740853,0.00021530376,0.000063064945],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012469014,0.00027092695,0.3786006,0.0000412277,0.0002584943,7.43082e-7,0.00026223867,2.5691006e-7,0.6181673,0.00060738175,0.00008680488,0.001691568],"study_design_scores_gemma":[0.0030609844,0.00033574575,0.97824526,0.00017952624,0.00012062548,0.0000017138285,0.000050775838,0.00007900391,0.014991488,0.00032389775,0.0023218126,0.0002891691],"about_ca_topic_score_codex":0.00027947704,"about_ca_topic_score_gemma":0.000056991154,"teacher_disagreement_score":0.6031758,"about_ca_system_score_codex":0.000049934803,"about_ca_system_score_gemma":0.000040418116,"threshold_uncertainty_score":0.999954},"labels":[],"label_agreement":null},{"id":"W2607489624","doi":"10.1093/cvr/cvx064","title":"ULK1 prevents cardiac dysfunction in obesity through autophagy-meditated regulation of lipid metabolism","year":2017,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Ewha Womans University; National Research Foundation","keywords":"Autophagy; Lipotoxicity; Endocrinology; Internal medicine; Lipoprotein lipase; Lipid metabolism; Cardiac function curve; MYH6; Adipose triglyceride lipase; Biology; Adipose tissue; Medicine; Cell biology; Heart failure; Lipolysis; Obesity; MYH7; Biochemistry; Insulin resistance","score_opus":0.0672252172690321,"score_gpt":0.3687944798798068,"score_spread":0.30156926261077466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2607489624","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9793398,0.012444763,0.00024653773,0.00012108505,0.00065652316,0.001156928,0.000015172716,0.000043426313,0.005975801],"genre_scores_gemma":[0.9961017,0.0017565638,0.00018271743,0.000014477573,0.00076074526,0.000096866715,0.00005974701,0.000037110254,0.0009901241],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9963736,0.0006675136,0.00035437022,0.00048321797,0.0016559147,0.00046536967],"domain_scores_gemma":[0.99705344,0.00007449506,0.00010075589,0.0021044451,0.00051467103,0.00015220806],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0034301993,0.00017239743,0.0008027837,0.00024854243,0.00032523467,0.000046494002,0.00032112788,0.00021621228,0.0001290635],"category_scores_gemma":[0.0006981347,0.00015726412,0.0008921099,0.00034440632,0.0003503027,0.0003805226,0.00016179992,0.00048536787,0.000066625],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0077057034,0.0059490125,0.2190306,0.005058622,0.04013851,0.0017244605,0.008960607,0.0016001088,0.27153167,0.008712702,0.020214135,0.40937385],"study_design_scores_gemma":[0.003155532,0.000096971125,0.87756675,0.00019691337,0.00025464737,0.000008744442,0.000089456444,0.00015499168,0.097344294,0.0014923677,0.019501882,0.0001374133],"about_ca_topic_score_codex":0.0004356375,"about_ca_topic_score_gemma":0.0000032254475,"teacher_disagreement_score":0.6585362,"about_ca_system_score_codex":0.00015876112,"about_ca_system_score_gemma":0.00025351552,"threshold_uncertainty_score":0.6413045},"labels":[],"label_agreement":null},{"id":"W2610948238","doi":"10.1016/j.freeradbiomed.2017.05.005","title":"Differential redox sensitivity of cathepsin B and L holds the key to autophagy-apoptosis interplay after Thioredoxin reductase inhibition in nutritionally stressed SH-SY5Y cells","year":2017,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autophagy; Thioredoxin reductase; Cell biology; Programmed cell death; Oxidative stress; Cathepsin B; Apoptosis; Cathepsin; Cathepsin L; Thioredoxin; Cathepsin D; Biology; Lysosome; Downregulation and upregulation; Chemistry; Biochemistry; Enzyme","score_opus":0.010396627816164348,"score_gpt":0.2981798416132736,"score_spread":0.28778321379710925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2610948238","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9812145,0.00096117554,0.0001796747,0.016660819,0.00024198563,0.0004091175,0.00016992724,0.000015699296,0.00014708965],"genre_scores_gemma":[0.99732566,0.00056847226,0.00013986294,0.0013737242,0.000391913,0.00003920125,0.00007561038,0.0000106214575,0.00007490847],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987493,0.00020035937,0.00032962096,0.00034024677,0.00014845705,0.00023199462],"domain_scores_gemma":[0.9988618,0.00024284144,0.00011978878,0.000489043,0.000051154024,0.00023537026],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042543927,0.00018673185,0.0004884031,0.00012706671,0.0001410998,0.000009225828,0.00009115876,0.00022720345,0.00020476182],"category_scores_gemma":[0.00045197815,0.00011356871,0.00005509405,0.000062132145,0.0015773465,0.000051706375,0.00012250846,0.0002876793,0.0000022267839],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032153232,0.0005364064,0.009341796,0.00014099358,0.00013913668,0.00024820602,0.0013670623,1.9107638e-7,0.97499377,0.0018270334,0.0025192,0.0056708935],"study_design_scores_gemma":[0.009744677,0.0016313121,0.5880312,0.0012751675,0.00026846677,0.00014373744,0.00016266144,0.00013778279,0.39150995,0.005577909,0.0012768672,0.00024027251],"about_ca_topic_score_codex":0.0002984148,"about_ca_topic_score_gemma":0.000088315304,"teacher_disagreement_score":0.5834838,"about_ca_system_score_codex":0.00002145018,"about_ca_system_score_gemma":0.000050939612,"threshold_uncertainty_score":0.58117986},"labels":[],"label_agreement":null},{"id":"W2611506526","doi":"","title":"The elicitor cryptogein blocks glucose transport in tabacco cells.","year":2003,"lang":"fr","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministère des Transports","funders":"","keywords":"Elicitor; Chemistry; Computer science; Biochemistry; Gene","score_opus":0.009515323884469096,"score_gpt":0.23301598056343756,"score_spread":0.22350065667896846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2611506526","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8229723,0.05406367,0.012939382,0.01964841,0.0026990508,0.0021104715,0.0001801505,0.00023675681,0.08514979],"genre_scores_gemma":[0.90113014,0.031015469,0.005676701,0.00059588306,0.00021230905,0.00029375256,0.00048445223,0.00014763925,0.06044364],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.98961693,0.006182785,0.0012505731,0.0011338467,0.00079163583,0.0010242374],"domain_scores_gemma":[0.991625,0.0023055782,0.0006162201,0.0034694858,0.0014492054,0.00053449237],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.007837738,0.0006987355,0.00078769296,0.00020397002,0.0006626664,0.00021547594,0.0015794912,0.0006472524,0.0012333869],"category_scores_gemma":[0.0007929977,0.0006258593,0.0005583908,0.0007279655,0.0007319687,0.00012726882,0.0003426703,0.0016113641,0.0002774489],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00079784886,0.013014558,0.042644482,0.0012857466,0.0017117823,0.00067510124,0.04650509,0.00057131983,0.08922216,0.44910863,0.00974564,0.34471765],"study_design_scores_gemma":[0.0047630146,0.0000029170108,0.056948792,0.007667331,0.00043597794,0.00004148221,0.0008108197,0.005230059,0.47381037,0.007730657,0.44122708,0.0013314926],"about_ca_topic_score_codex":0.002165969,"about_ca_topic_score_gemma":0.0026251413,"teacher_disagreement_score":0.44137797,"about_ca_system_score_codex":0.00040822857,"about_ca_system_score_gemma":0.0010319604,"threshold_uncertainty_score":0.9996796},"labels":[],"label_agreement":null},{"id":"W2612407789","doi":"10.1183/13993003.congress-2016.oa3024","title":"Differential regulation of protein degradation pathways in the ventilatory and limb muscles in response to sepsis","year":2016,"lang":"en","type":"article","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Autophagy; PI3K/AKT/mTOR pathway; Sepsis; Muscle atrophy; Atrophy; Medicine; Downregulation and upregulation; ATG12; Protein kinase B; Protein degradation; Calpain; AMPK; Internal medicine; Endocrinology; Cell biology; Phosphorylation; Signal transduction; Biology; Protein kinase A; Apoptosis; Biochemistry; ATG5","score_opus":0.019249587796779658,"score_gpt":0.26040540910882926,"score_spread":0.2411558213120496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2612407789","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981497,0.00004502715,0.00019083038,0.0010766446,0.000011460975,0.0004422231,0.0000024265091,0.000008503516,0.00007318181],"genre_scores_gemma":[0.99951285,0.000008625963,0.000078717785,0.000099787154,0.000015352642,0.000036790327,0.0000022663885,0.000004612477,0.00024097475],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99949676,0.000084690735,0.00014063196,0.00009331156,0.000118150885,0.00006647015],"domain_scores_gemma":[0.9997347,0.0000603527,0.000028821392,0.0001350857,0.000015438085,0.000025601159],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020766504,0.000047788675,0.000086139386,0.000116334995,0.0000108115555,0.0000032076,0.000030470617,0.000028961917,0.00011327141],"category_scores_gemma":[0.000054683493,0.00002495416,0.000020909783,0.00009466681,0.00002241008,0.000043557277,0.000009750577,0.000025337204,0.0000028805632],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0031886385,0.00015576615,0.017237838,0.000018899911,0.000006777464,0.0000059947215,0.00062806805,2.337241e-7,0.9586248,0.0008401354,0.000028984845,0.019263873],"study_design_scores_gemma":[0.0010385229,0.00017943174,0.8916576,0.0001337624,0.000005820326,9.031058e-7,0.00011637044,0.000024761579,0.106006384,0.00071963534,0.0000856813,0.000031117655],"about_ca_topic_score_codex":0.000017503975,"about_ca_topic_score_gemma":0.000030179082,"teacher_disagreement_score":0.87441975,"about_ca_system_score_codex":0.000020907184,"about_ca_system_score_gemma":0.000026098987,"threshold_uncertainty_score":0.12402425},"labels":[],"label_agreement":null},{"id":"W2615178041","doi":"10.1007/s00705-017-3400-7","title":"MicroRNA-30a-5p promotes replication of porcine circovirus type 2 through enhancing autophagy by targeting 14-3-3","year":2017,"lang":"en","type":"article","venue":"Archives of Virology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Agriculture","funders":"National Natural Science Foundation of China","keywords":"Porcine circovirus; Biology; Autophagy; Viral replication; microRNA; Circovirus; Virus; Virology; Cell biology; Gene; Genetics; Apoptosis","score_opus":0.016707450831520004,"score_gpt":0.31551091067990095,"score_spread":0.29880345984838097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2615178041","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905163,0.0030958648,0.00092414935,0.00080501137,0.00012099677,0.00028590448,0.000022115662,0.000033847882,0.0041957814],"genre_scores_gemma":[0.995656,0.0004841586,0.0028763935,0.00033941976,0.00010455161,0.000010563135,0.00007448888,0.000024861183,0.0004295286],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998804,0.00006407717,0.00042368207,0.00036057585,0.0001111633,0.00023654473],"domain_scores_gemma":[0.99814796,0.00015344725,0.00055720547,0.0010264965,0.00004955882,0.00006533763],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016526016,0.00014311474,0.00043599695,0.00006125971,0.00013313131,0.000005229704,0.00027926374,0.00008971994,0.00011659468],"category_scores_gemma":[0.00044200916,0.00012861345,0.00010779411,0.000040668794,0.00043796957,0.00008236763,0.00009264385,0.00015038242,0.000012882446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005541376,0.00021600879,0.004400705,0.000115318006,0.00013215175,0.000010584285,0.0008630499,0.0000011697689,0.9852386,0.0006508644,0.00032998106,0.007487408],"study_design_scores_gemma":[0.0012219534,0.00071888254,0.08598483,0.00007117178,0.00008202863,0.000017635046,0.000032520104,0.00009874774,0.9050611,0.004424853,0.0021916742,0.00009457053],"about_ca_topic_score_codex":0.00014718751,"about_ca_topic_score_gemma":0.0000048508823,"teacher_disagreement_score":0.081584126,"about_ca_system_score_codex":0.0000075406574,"about_ca_system_score_gemma":0.00008087533,"threshold_uncertainty_score":0.52447045},"labels":[],"label_agreement":null},{"id":"W2616723098","doi":"10.3389/fphy.2017.00014","title":"A Model of Autophagy Size Selectivity by Receptor Clustering on Peroxisomes","year":2017,"lang":"en","type":"article","venue":"Frontiers in Physics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Killam Trusts","keywords":"Organelle; Peroxisome; Autophagy; Cell biology; Lysosome; Biology; Chemistry; Receptor; Biochemistry; Enzyme","score_opus":0.01952158878961494,"score_gpt":0.27834364627564073,"score_spread":0.25882205748602577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2616723098","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97848666,0.0002863987,0.01674779,0.00019092551,0.00045229035,0.0002701763,0.00004946112,0.000040952717,0.0034753568],"genre_scores_gemma":[0.9930371,0.00012442358,0.005166629,0.0002097774,0.00014835413,0.000018504448,0.000007747785,0.000027085858,0.0012603581],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992034,0.000021534966,0.00015301192,0.00022363751,0.0001954201,0.00020303788],"domain_scores_gemma":[0.99920225,0.00002524085,0.00013976474,0.00052486797,0.000034937664,0.0000729257],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008079046,0.0001422315,0.0003630348,0.000027755392,0.00009901992,0.000015194319,0.00017582711,0.00007741524,0.000014240284],"category_scores_gemma":[0.00007152342,0.00013511755,0.00010306299,0.000050728308,0.00011181615,0.00013773784,0.000040675382,0.00017528598,0.000004264986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005208531,0.0056449026,0.11457079,0.0008314531,0.001131425,0.000040401443,0.004769219,0.0057244217,0.350556,0.0017747736,0.16098343,0.34876466],"study_design_scores_gemma":[0.0077346,0.0007880092,0.027957037,0.00045635557,0.0001379161,0.0000015990805,0.0001894582,0.431645,0.50645787,0.022943305,0.0010839268,0.0006049613],"about_ca_topic_score_codex":0.000019782077,"about_ca_topic_score_gemma":0.0000010616005,"teacher_disagreement_score":0.42592058,"about_ca_system_score_codex":0.000091665774,"about_ca_system_score_gemma":0.000080876984,"threshold_uncertainty_score":0.5509933},"labels":[],"label_agreement":null},{"id":"W2618463845","doi":"10.1139/bcb-2016-0158","title":"MicroRNA-34a protects myocardial cells against ischemia–reperfusion injury through inhibiting autophagy via regulating TNFα expression","year":2017,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Department of Science and Technology, Ministry of Science and Technology, India","keywords":"Autophagy; In vivo; Reperfusion injury; Apoptosis; Cardioprotection; Viability assay; Ischemia; Medicine; Flow cytometry; Western blot; Tumor necrosis factor alpha; Myocardial infarction; Transfection; Pharmacology; Chemistry; Biology; Internal medicine; Immunology; Cell culture; Biochemistry","score_opus":0.009888435459245991,"score_gpt":0.2641352831845042,"score_spread":0.2542468477252582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2618463845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98916066,0.0016352795,0.00007506146,0.0001190903,0.0002031842,0.0003166831,0.000023601478,0.0000807752,0.008385649],"genre_scores_gemma":[0.9966027,0.00030135244,0.0009810354,0.00041841806,0.00079732825,0.000033514207,0.0000995958,0.000028904122,0.0007371206],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99853545,0.000044216227,0.0003200414,0.0006013198,0.00010708606,0.00039187362],"domain_scores_gemma":[0.9987489,0.000034076565,0.00034229673,0.00064152415,0.00006145356,0.00017176788],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016648897,0.00029287097,0.00038200896,0.000021956874,0.0006146385,0.000042779193,0.00017898949,0.0005161302,0.000072734016],"category_scores_gemma":[0.00007064507,0.0002485644,0.00014305445,0.000035595636,0.000316833,0.00008535272,0.00025730437,0.00032387086,0.0000142658555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030144097,0.000090415015,0.00024425742,0.00022709377,0.000028039629,0.000033783934,0.00011996383,3.6640358e-7,0.9879344,0.0000044949875,0.00030452517,0.010711203],"study_design_scores_gemma":[0.0014395445,0.000127734,0.000087961715,0.00025640527,0.00003622752,0.000021247173,0.000070689915,0.00006325689,0.9947551,0.00013705969,0.0027373394,0.0002674505],"about_ca_topic_score_codex":0.000016768847,"about_ca_topic_score_gemma":9.159374e-8,"teacher_disagreement_score":0.010443754,"about_ca_system_score_codex":0.000034965255,"about_ca_system_score_gemma":0.00009268089,"threshold_uncertainty_score":0.99999666},"labels":[],"label_agreement":null},{"id":"W2621364082","doi":"10.1038/s41598-017-03494-2","title":"Activity-independent targeting of mTOR to lysosomes in primary osteoclasts","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"Canadian Institutes of Health Research; Arthritis Society","keywords":"Lysosome; mTORC1; Autophagy; PI3K/AKT/mTOR pathway; mTORC2; Cell biology; Bafilomycin; V-ATPase; Mechanistic target of rapamycin; RPTOR; Chemistry; Biology; Biochemistry; Signal transduction; ATPase; Enzyme","score_opus":0.015369179732813529,"score_gpt":0.2934890818445183,"score_spread":0.27811990211170473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2621364082","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99011207,0.00012989488,0.000017470173,0.00032821012,0.0026842058,0.0004159033,0.000001853558,0.000023841776,0.0062865694],"genre_scores_gemma":[0.9949928,0.0000035408816,0.00025416617,0.00005871852,0.00008567457,0.000017221339,0.0000108516815,0.00001332268,0.004563739],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9982834,0.000022935037,0.0003633312,0.0005046324,0.00057139655,0.0002543421],"domain_scores_gemma":[0.9980945,0.000018982613,0.00037833647,0.0012206739,0.000108327935,0.00017920225],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010505255,0.00011045395,0.00030247416,0.00020182683,0.0002150125,0.00009521681,0.00014394634,0.00005812391,0.00013708867],"category_scores_gemma":[0.0003312966,0.000094888484,0.000102746286,0.00013370287,0.00014871905,0.00019749187,0.00012968655,0.00010473503,0.000022480383],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019421909,0.0004313143,0.259037,0.00015084357,0.00004424295,0.0027280112,0.00068233086,0.000016433487,0.71600527,0.000019708938,0.0040143975,0.016676258],"study_design_scores_gemma":[0.0004695783,0.00006536071,0.6291572,0.00017676812,0.000021139875,0.00007505348,0.000050087387,0.000020285306,0.364265,0.0006291199,0.0049532745,0.000117135656],"about_ca_topic_score_codex":0.000051549145,"about_ca_topic_score_gemma":0.000015304011,"teacher_disagreement_score":0.37012023,"about_ca_system_score_codex":0.00008349396,"about_ca_system_score_gemma":0.0002989651,"threshold_uncertainty_score":0.386944},"labels":[],"label_agreement":null},{"id":"W2622198941","doi":"10.1016/j.molcel.2017.05.020","title":"Autophagy-Dependent Shuttling of TBC1D5 Controls Plasma Membrane Translocation of GLUT1 and Glucose Uptake","year":2017,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":155,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Cancer Institute; Samuel Waxman Cancer Research Foundation; Government of Canada; U.S. Department of Defense","keywords":"Retromer; Autophagy; Cell biology; GLUT1; Endosome; Biology; Glucose transporter; Sorting nexin; Intracellular; Biochemistry; Endocrinology","score_opus":0.010390191279845298,"score_gpt":0.25708079728689753,"score_spread":0.24669060600705223,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2622198941","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908538,0.0042602457,0.001373641,0.00014679943,0.00007817285,0.0003737884,0.0000173688,0.000019706935,0.002876502],"genre_scores_gemma":[0.998603,0.0004574162,0.0005567504,0.00010231464,0.000028418943,0.000010671984,0.000012857279,0.000024213872,0.0002043786],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902135,0.0000294465,0.00031678416,0.00021059977,0.00026538968,0.00015642444],"domain_scores_gemma":[0.99899346,0.000022873073,0.00023707151,0.0005506492,0.00008384811,0.00011208134],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017138578,0.00013832306,0.00037195985,0.000061953695,0.000069770766,0.000015287182,0.00013999444,0.000096917385,0.00006635566],"category_scores_gemma":[0.00003842568,0.00012752821,0.00012362782,0.000029680317,0.0001225785,0.00005867864,0.000021870297,0.00009340719,0.000005262976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036224825,0.00022604031,0.0002592458,0.00023752793,0.000116691575,0.00010519985,0.00023989058,0.000050253017,0.9859333,0.00042625118,0.0000036113954,0.012039718],"study_design_scores_gemma":[0.0052752052,0.00021002702,0.005757156,0.0001065391,0.00019500557,0.000009495324,0.00004201367,0.0015398501,0.9863696,0.00019417648,0.00020426876,0.00009666884],"about_ca_topic_score_codex":0.00004643956,"about_ca_topic_score_gemma":0.0000029187092,"teacher_disagreement_score":0.01194305,"about_ca_system_score_codex":0.000012189166,"about_ca_system_score_gemma":0.00007263157,"threshold_uncertainty_score":0.520045},"labels":[],"label_agreement":null},{"id":"W2622769153","doi":"10.1038/ncomms15750","title":"Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":352,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"National Center for Complementary and Integrative Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Foundation for Barnes-Jewish Hospital; U.S. Department of Veterans Affairs","keywords":"Autophagy; TFEB; Macrophage; Cell biology; Lysosome; Biogenesis; Biology; Chemistry; Apoptosis; Biochemistry; Gene","score_opus":0.05742648204749348,"score_gpt":0.3749436929933685,"score_spread":0.31751721094587504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2622769153","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9631788,0.019257845,0.00012066122,0.00898191,0.00026206483,0.0011835063,0.00014774724,0.00024229719,0.006625143],"genre_scores_gemma":[0.98270893,0.005137028,0.00761254,0.0027373305,0.00022761148,0.00045533347,0.00014762155,0.00006275683,0.0009108542],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989226,0.000060158647,0.00025164295,0.0002828675,0.00019777272,0.00028495488],"domain_scores_gemma":[0.9950404,0.00021695212,0.00023955453,0.0040970524,0.00023972026,0.00016628848],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.00021918998,0.00020646736,0.0002914978,0.000085593914,0.0017393102,0.0001300409,0.0013740475,0.00034997318,0.0001254486],"category_scores_gemma":[0.000358456,0.00018120842,0.00031413612,0.00009548635,0.00025782903,0.00017607924,0.00022177334,0.00047285846,0.00006348045],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019624943,0.0041255667,0.08426936,0.00015485952,0.002200509,0.000029645602,0.0025175083,0.0000022398633,0.57637626,0.0856274,0.012626072,0.2301081],"study_design_scores_gemma":[0.008584155,0.00056206645,0.5825829,0.00023243592,0.0003032932,0.000041488755,0.00029089805,0.0006453761,0.2090498,0.0030639314,0.19405244,0.00059123314],"about_ca_topic_score_codex":0.000052861702,"about_ca_topic_score_gemma":0.000024657513,"teacher_disagreement_score":0.49831352,"about_ca_system_score_codex":0.00005524638,"about_ca_system_score_gemma":0.00013842224,"threshold_uncertainty_score":0.9995603},"labels":[],"label_agreement":null},{"id":"W2622926985","doi":"10.1007/s00109-017-1533-5","title":"Induced pluripotent stem cell-based modeling of neurodegenerative diseases: a focus on autophagy","year":2017,"lang":"en","type":"review","venue":"Journal of Molecular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"FP7 Health; European Regional Development Fund; Bundesministerium für Bildung und Forschung; European Commission; Stem Cell Network","keywords":"Autophagy; Induced pluripotent stem cell; Reprogramming; Biology; Cell biology; Context (archaeology); Neurodegeneration; Disease; Regenerative medicine; Neuroscience; Cell; Stem cell; Medicine; Genetics; Embryonic stem cell; Pathology; Apoptosis; Gene","score_opus":0.09204356591581538,"score_gpt":0.3736142546818003,"score_spread":0.28157068876598496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2622926985","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0028467171,0.9923184,0.0024442617,0.00038666028,0.000639927,0.00088064873,0.000030300369,0.000017461292,0.00043561897],"genre_scores_gemma":[0.091555774,0.9066541,0.0001101964,0.00052758295,0.0008785051,0.000023026234,0.00003252599,0.00013514739,0.00008311649],"study_design_codex":"design_other","study_design_gemma":"systematic_review","domain_scores_codex":[0.995448,0.00041393779,0.0019454905,0.00041939443,0.0014294289,0.00034378396],"domain_scores_gemma":[0.9944988,0.00015641369,0.0030606238,0.0010782378,0.0005715278,0.00063439034],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004751136,0.0006914262,0.0042465245,0.0008103376,0.000090310685,0.000016394764,0.0005831144,0.00034431278,0.000071143695],"category_scores_gemma":[0.00021703316,0.0004357043,0.0015811572,0.00022018114,0.00014324108,0.0000604935,0.00004889166,0.0010742673,0.0000071317536],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010903716,0.0015305001,0.0000022442623,0.0184744,0.0024682768,0.0130413035,0.00020516606,0.0012649263,0.0026401924,0.0001251262,0.00036222662,0.95879525],"study_design_scores_gemma":[0.05112671,0.04470802,0.0000499976,0.49379697,0.084858306,0.0027410425,0.00043238545,0.014492556,0.028072761,0.0010076527,0.2754968,0.0032167851],"about_ca_topic_score_codex":0.000010760301,"about_ca_topic_score_gemma":2.0868372e-7,"teacher_disagreement_score":0.9555785,"about_ca_system_score_codex":0.00020143494,"about_ca_system_score_gemma":0.002002152,"threshold_uncertainty_score":0.9998095},"labels":[],"label_agreement":null},{"id":"W2623628037","doi":"10.1016/j.biopha.2017.05.132","title":"An oasis in the desert of cancer chemotherapeutic resistance: The enlightenment from reciprocal crosstalk between signaling pathways of UPR and autophagy in cancers","year":2017,"lang":"en","type":"review","venue":"Biomedicine & Pharmacotherapy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China; McGill University Health Centre","keywords":"Autophagy; ATF4; Crosstalk; Unfolded protein response; Cell biology; Endoplasmic reticulum; Biology; Signal transduction; Transcription factor; XBP1; Cancer research; Apoptosis; Gene; Biochemistry","score_opus":0.16577036609015056,"score_gpt":0.48056023299500805,"score_spread":0.3147898669048575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2623628037","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.102004476,0.8951032,0.000010910487,0.00035992396,0.00017971256,0.00189396,0.00035948266,0.000018400087,0.00006989184],"genre_scores_gemma":[0.10048847,0.89735025,0.00007689066,0.00074806256,0.00070842163,0.00036976504,0.000111799156,0.00008780983,0.000058512192],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99640286,0.0004332334,0.0013271243,0.00063052244,0.0007527194,0.00045351937],"domain_scores_gemma":[0.9972375,0.00048358904,0.0010376157,0.0010000358,0.0000808153,0.00016045806],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011715785,0.0006049788,0.0024563293,0.0003557701,0.000121741374,0.000027629505,0.000880973,0.00030391724,0.00023523052],"category_scores_gemma":[0.00001673036,0.0003232466,0.00032958892,0.0005590003,0.00077440956,0.00009221153,0.00003133734,0.00060303195,0.0000011187194],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005585298,0.00028934484,0.0013932363,0.0034171906,0.0011134781,0.000068544025,0.004063197,5.375844e-7,0.0063578538,0.000011227087,0.00010978247,0.9826171],"study_design_scores_gemma":[0.011627681,0.00084925763,0.012596241,0.033312608,0.0038141292,0.000013800095,0.0006491353,0.000051539795,0.01737076,0.00034567917,0.918592,0.00077718584],"about_ca_topic_score_codex":0.0025047977,"about_ca_topic_score_gemma":0.00017513565,"teacher_disagreement_score":0.9818399,"about_ca_system_score_codex":0.00035060296,"about_ca_system_score_gemma":0.0010282377,"threshold_uncertainty_score":0.999922},"labels":[],"label_agreement":null},{"id":"W2731353557","doi":"10.1155/2017/3749157","title":"Lysosomes as Oxidative Targets for Cancer Therapy","year":2017,"lang":"en","type":"review","venue":"Oxidative Medicine and Cellular Longevity","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":120,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; University of Manitoba; Research Institute in Oncology and Hematology; Providence University College and Theological Seminary","funders":"","keywords":"Autophagy; Cancer cell; Cell biology; Reactive oxygen species; Programmed cell death; Oxidative stress; Lysosome; Mitochondrion; Apoptosis; Biology; Cancer; Chemistry; Biochemistry; Enzyme","score_opus":0.15969642146334642,"score_gpt":0.4360958696379924,"score_spread":0.276399448174646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2731353557","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00059783785,0.9911208,0.0002771034,0.0006852945,0.0004853492,0.0037341092,0.00021641592,0.00007086232,0.0028121977],"genre_scores_gemma":[0.00022635212,0.9851364,0.00010107603,0.00068573613,0.0017453134,0.0010405863,0.00097633654,0.00013495142,0.009953276],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969092,0.00025591173,0.00073398766,0.0010468798,0.00048595655,0.0005680583],"domain_scores_gemma":[0.99671656,0.00046905054,0.00096444954,0.0010424777,0.0003045827,0.000502875],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006269771,0.0009776036,0.004029137,0.00028039626,0.00044836258,0.000041279025,0.00037967518,0.0004896172,0.0013873315],"category_scores_gemma":[0.00040836498,0.00061518553,0.00074083434,0.00017808563,0.0008655025,0.00016562865,0.00009704077,0.00060124486,0.000053964006],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022030671,0.0002023558,0.000035047484,0.007511954,0.0020657945,0.0001598248,0.00047579026,1.011348e-8,0.00016854548,0.0003371769,0.0038339668,0.9849892],"study_design_scores_gemma":[0.0028223058,0.001047755,0.00004536423,0.012560012,0.003042952,0.000031759246,0.00011424525,0.0000025981751,0.0013763454,0.000570855,0.9778168,0.0005689999],"about_ca_topic_score_codex":0.00017201707,"about_ca_topic_score_gemma":0.000009312917,"teacher_disagreement_score":0.98442024,"about_ca_system_score_codex":0.00013132463,"about_ca_system_score_gemma":0.0006727936,"threshold_uncertainty_score":0.99963},"labels":[],"label_agreement":null},{"id":"W2734362632","doi":"10.3390/ijms18071496","title":"Clinical Applications of Autophagy Proteins in Cancer: From Potential Targets to Biomarkers","year":2017,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; Canada's Michael Smith Genome Sciences Centre; University of British Columbia; BC Cancer Agency","funders":"University of British Columbia; Canadian Institutes of Health Research; Avon Foundation for Women","keywords":"Autophagy; Context (archaeology); Biomarker; Clinical trial; Biology; Lysosome; Carcinogenesis; Computational biology; Bioinformatics; Cancer; Medicine; Biochemistry; Genetics","score_opus":0.07682605743887191,"score_gpt":0.4796715170044172,"score_spread":0.4028454595655453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2734362632","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0025083886,0.9924921,0.0027612809,0.0003893547,0.00090106815,0.0005961499,0.00009294547,0.0000040795635,0.00025467548],"genre_scores_gemma":[0.0113873985,0.98393124,0.003866086,0.00016758924,0.0005307277,0.00005625639,0.000013717831,0.00001399021,0.000032964497],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973343,0.00012253739,0.0011783412,0.00027277446,0.00095095806,0.00014110365],"domain_scores_gemma":[0.99769807,0.00007243975,0.0014412883,0.00024124449,0.0003725936,0.0001743831],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00079444225,0.00017040884,0.0009773253,0.0005884764,0.000041424228,0.00005039605,0.0013217475,0.00013979147,0.000114531664],"category_scores_gemma":[0.0001730266,0.00012541276,0.0006810518,0.00020515839,0.00028760105,0.00010155391,0.00010645286,0.0002702818,0.000009106731],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006189974,0.0002686023,0.00016947869,0.00014684383,0.000814629,0.00046465464,0.00002089743,0.000014240475,0.00012780954,0.00008825383,0.00006917782,0.9977535],"study_design_scores_gemma":[0.0015424481,0.00057874725,0.0023518023,0.015675096,0.0007421929,0.00020588971,0.000029774412,0.000048428326,0.0007525871,0.0012262109,0.9765471,0.00029970123],"about_ca_topic_score_codex":0.00017746509,"about_ca_topic_score_gemma":0.00000877731,"teacher_disagreement_score":0.9974538,"about_ca_system_score_codex":0.000102949685,"about_ca_system_score_gemma":0.0021910418,"threshold_uncertainty_score":0.51141834},"labels":[],"label_agreement":null},{"id":"W2735367257","doi":"10.1038/mp.2017.142","title":"Synaptic activity protects against AD and FTD-like pathology via autophagic-lysosomal degradation","year":2017,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; University of Toronto; Krembil Foundation; University Health Network","funders":"Ministerio de Economía y Competitividad; Euskal Herriko Unibertsitatea; Fondation pour la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Autophagy; Neuroscience; Pathology; Medicine; Psychology; Chemistry; Biochemistry; Apoptosis","score_opus":0.00894608005355912,"score_gpt":0.2691781747568647,"score_spread":0.26023209470330555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2735367257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98865944,0.0026606552,0.0038095026,0.0023608773,0.00063326064,0.00063703646,0.0000060779425,0.00010250484,0.0011306442],"genre_scores_gemma":[0.99566305,0.00008997407,0.0022294465,0.0016241779,0.00010377961,0.00006330408,0.000017872535,0.00003963731,0.00016875856],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99882513,0.00007975017,0.00016435566,0.0004336126,0.00020882297,0.0002883066],"domain_scores_gemma":[0.9986955,0.000008941108,0.0001807156,0.00088066637,0.000045660763,0.00018850165],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012600339,0.00022096658,0.0002963683,0.00008029803,0.00033937703,0.000054061296,0.00015909843,0.00016585537,0.00003344004],"category_scores_gemma":[0.000046455745,0.00020397427,0.00012252701,0.000048614536,0.00016664006,0.00012765921,0.000070255315,0.0002598875,0.000038061386],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011673147,0.0013924695,0.020292578,0.0005132611,0.0011012956,0.0028980104,0.00019525428,0.0000053964154,0.80444837,0.0015629418,0.00032491056,0.16609818],"study_design_scores_gemma":[0.0071065067,0.0011016005,0.90961695,0.00025744463,0.00040671564,0.00077091454,0.000039188722,0.0019680364,0.07045425,0.0063774046,0.001193002,0.0007079861],"about_ca_topic_score_codex":0.000011738605,"about_ca_topic_score_gemma":0.000008965563,"teacher_disagreement_score":0.88932437,"about_ca_system_score_codex":0.000028807208,"about_ca_system_score_gemma":0.00013782,"threshold_uncertainty_score":0.83178294},"labels":[],"label_agreement":null},{"id":"W2735492323","doi":"10.1038/cddis.2017.317","title":"Inhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia","year":2017,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Alberta","keywords":"Autophagy; ATG5; CD34; Myeloid leukemia; Cancer research; Gene knockdown; Programmed cell death; Biology; Apoptosis; Leukemia; Haematopoiesis; Myeloid; Stem cell; Cell biology; Immunology; Biochemistry","score_opus":0.02661531188400139,"score_gpt":0.3091838362297483,"score_spread":0.2825685243457469,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2735492323","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921438,0.0026609222,0.00005767566,0.00011656065,0.00008167914,0.0005868772,0.0001234441,0.000032702017,0.0041963],"genre_scores_gemma":[0.9942205,0.0011844385,0.00009814361,0.00032101056,0.00014300438,0.00005792503,0.00018275583,0.000019737136,0.0037724809],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992473,0.000011304382,0.00016206491,0.00025153917,0.00011127727,0.00021649821],"domain_scores_gemma":[0.99872863,0.000021213684,0.00011889636,0.0004401479,0.000072765055,0.00061836373],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003830293,0.00016677212,0.00025906862,0.00004425804,0.0002206398,0.00003718504,0.000053998723,0.00006289974,0.000106576175],"category_scores_gemma":[0.0000383846,0.00013148435,0.00014206616,0.000022354132,0.00008473904,0.00010513059,0.00002095678,0.000035967656,0.000017274258],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.10229972,0.012551883,0.12403559,0.0058393516,0.004388256,0.008782592,0.0030981167,0.00016302332,0.38719407,0.037779562,0.012495865,0.30137196],"study_design_scores_gemma":[0.043547574,0.009580028,0.4898542,0.0004410826,0.0060999836,0.000045088702,0.00025333988,0.0030687624,0.3947865,0.041836794,0.009507867,0.0009787895],"about_ca_topic_score_codex":0.000066877314,"about_ca_topic_score_gemma":0.00000124582,"teacher_disagreement_score":0.36581862,"about_ca_system_score_codex":0.000063599146,"about_ca_system_score_gemma":0.00063160976,"threshold_uncertainty_score":0.53617764},"labels":[],"label_agreement":null},{"id":"W2735499363","doi":"10.2131/jts.42.461","title":"Ephedrine-induced mitophagy via oxidative stress in human hepatic stellate cells","year":2017,"lang":"en","type":"article","venue":"The Journal of Toxicological Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"National Center for Inter-University Research Facilities, Seoul National University; Seoul National University","keywords":"Ephedrine; Oxidative stress; Pharmacology; Chemistry; Mitochondrion; Mitophagy; Autophagy; Medicine; Biochemistry; Apoptosis","score_opus":0.06391235557309313,"score_gpt":0.3720571712415235,"score_spread":0.3081448156684303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2735499363","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957458,0.00022618592,0.000028006285,0.0013020006,0.00022432917,0.00017708284,0.0000010016737,0.000005923672,0.0022896724],"genre_scores_gemma":[0.9990736,0.00012979099,0.0001245334,0.00034125574,0.00018841641,0.000001312987,1.1473101e-7,0.0000035579872,0.00013737474],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986029,0.00019753567,0.0003755911,0.00012370125,0.00044262016,0.00025764736],"domain_scores_gemma":[0.9987864,0.00022218403,0.0005384016,0.00023894117,0.00006613079,0.00014794737],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013118834,0.00011570672,0.00032770637,0.000073838746,0.0005262139,0.000065253786,0.00081795984,0.0000710347,0.00037744115],"category_scores_gemma":[0.00015756376,0.000053833854,0.00010565461,0.000114462135,0.0006098506,0.00019257555,0.00009643677,0.0002946371,0.000011387434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027405383,0.0006382577,0.026674787,0.000012668353,0.000055017084,0.00038620929,0.00046150212,0.00013185845,0.9662202,0.0001814735,0.00006664688,0.004897305],"study_design_scores_gemma":[0.0012315596,0.0032160184,0.3449701,0.00012683962,0.00005682564,0.000082309816,0.00032864857,0.00029951255,0.6441098,0.005433732,0.000037235317,0.00010745816],"about_ca_topic_score_codex":0.000042323853,"about_ca_topic_score_gemma":0.000029759101,"teacher_disagreement_score":0.32211044,"about_ca_system_score_codex":0.000046707068,"about_ca_system_score_gemma":0.000081875674,"threshold_uncertainty_score":0.41327158},"labels":[],"label_agreement":null},{"id":"W2739307379","doi":"10.14814/phy2.13307","title":"Regulation of the autophagy system during chronic contractile activity-induced muscle adaptations","year":2017,"lang":"en","type":"article","venue":"Physiological Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Downregulation and upregulation; Skeletal muscle; TFEB; Mitochondrial biogenesis; Lysosome; Cell biology; Mitochondrion; Biology; LAMP1; Endocrinology; Organelle biogenesis; Internal medicine; Chemistry; Biogenesis; Medicine; Biochemistry; Apoptosis; Gene","score_opus":0.03794225389769898,"score_gpt":0.30561943334728553,"score_spread":0.2676771794495866,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2739307379","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997244,0.00007246883,0.000016557808,0.00014834251,0.00026403603,0.00038409192,0.0000022861686,0.00006500747,0.0018031797],"genre_scores_gemma":[0.9994397,0.000009168286,0.000013899957,0.000017071052,0.00019744529,0.000038912956,0.0000035623566,0.000009330382,0.00027087962],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991067,0.00004772795,0.00024783114,0.00023165469,0.00021176934,0.00015431314],"domain_scores_gemma":[0.9983231,0.00003764298,0.00059843995,0.00089249323,0.00007974493,0.000068610534],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010155071,0.00010290307,0.00026616472,0.000016453498,0.00039632837,0.000015226236,0.00009770241,0.00008803959,0.000085093976],"category_scores_gemma":[0.0002657082,0.00006169852,0.0001777526,0.000039788767,0.00009910278,0.00011303429,0.000059836024,0.00013581435,0.000005022084],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057140835,0.0001221384,0.0007931849,0.000060261755,0.00004411315,0.00007818267,0.000021768668,0.000041470554,0.9960884,0.00033145584,0.000014289773,0.0023476148],"study_design_scores_gemma":[0.0002973547,0.000065240536,0.7589249,0.00009349253,0.00004076831,0.000047209724,0.000011817149,0.00045630438,0.23966959,0.0003117672,0.000033570686,0.000048010887],"about_ca_topic_score_codex":0.000054610977,"about_ca_topic_score_gemma":0.0000027057986,"teacher_disagreement_score":0.7581317,"about_ca_system_score_codex":0.00010134153,"about_ca_system_score_gemma":0.00011436919,"threshold_uncertainty_score":0.30482775},"labels":[],"label_agreement":null},{"id":"W2740151851","doi":"10.1007/978-3-319-59749-2_8","title":"Apoptosis, Autophagy, and Unfolded Protein Response and Cerebellar Development","year":2017,"lang":"en","type":"book-chapter","venue":"Contemporary clinical neuroscience","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autophagy; Unfolded protein response; Cell biology; Programmed cell death; Apoptosis; Biology; Cell fate determination; Neuroscience; Genetics; Transcription factor; Endoplasmic reticulum; Gene","score_opus":0.12493438173502251,"score_gpt":0.3673666354563959,"score_spread":0.2424322537213734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2740151851","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8818376,0.0089713195,0.000047608275,0.0030523452,0.0011825033,0.0033989863,0.00006518749,0.00028545564,0.10115901],"genre_scores_gemma":[0.6711187,0.00089423114,0.00024273997,0.0031434721,0.00015915609,0.000026963342,0.000010967757,0.000063373845,0.32434043],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969321,0.00012961235,0.0009410567,0.0012099817,0.00049019366,0.00029705284],"domain_scores_gemma":[0.9973116,0.00034041374,0.00057327293,0.00097394036,0.00009100144,0.00070975005],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013377997,0.00046422074,0.00092218095,0.00013306012,0.0004088651,0.00012600668,0.00037118484,0.00045485952,0.000042928463],"category_scores_gemma":[0.0009873676,0.00039264126,0.00016437615,0.000022453834,0.0017538925,0.00019092624,0.00037622915,0.0007039636,0.00003294849],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.07042697,0.0040873853,0.041702423,0.004368027,0.001374822,0.01870496,0.0018527702,4.5982415e-7,0.16248837,0.047100127,0.038388606,0.60950506],"study_design_scores_gemma":[0.004180879,0.0018720926,0.09975113,0.001529669,0.00010345018,0.00010794607,0.0000057822217,0.000043908145,0.0065870043,0.0035779905,0.881374,0.0008661232],"about_ca_topic_score_codex":0.000002936732,"about_ca_topic_score_gemma":5.4613184e-7,"teacher_disagreement_score":0.8429854,"about_ca_system_score_codex":0.000020796551,"about_ca_system_score_gemma":0.0014602764,"threshold_uncertainty_score":0.99985254},"labels":[],"label_agreement":null},{"id":"W2740908790","doi":"10.1002/ppul.23777","title":"mTOR‐Notch3 signaling mediates pulmonary hypertension in hypoxia‐exposed neonatal rats independent of changes in autophagy","year":2017,"lang":"en","type":"article","venue":"Pediatric Pulmonology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Toronto; University of Ottawa; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Canada Foundation for Innovation","keywords":"Autophagy; PI3K/AKT/mTOR pathway; Notch signaling pathway; Medicine; Hypoxia (environmental); Sirolimus; Pulmonary hypertension; Signal transduction; Cancer research; Pharmacology; Cell biology; Internal medicine; Biology; Receptor; Chemistry; Apoptosis","score_opus":0.024546067814663928,"score_gpt":0.26759667466179843,"score_spread":0.2430506068471345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2740908790","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902923,0.007265308,0.000009274428,0.0010022244,0.0005713235,0.00046573987,0.000015575892,0.000050127517,0.00032814158],"genre_scores_gemma":[0.9956958,0.0030038683,0.00015804791,0.00025853654,0.0006316067,0.000062706145,0.000041254967,0.000038485054,0.00010966368],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99789435,0.000106233376,0.00058240263,0.0005287583,0.0003217532,0.0005665175],"domain_scores_gemma":[0.9984364,0.00020017775,0.00040894016,0.00070009794,0.00008632491,0.000168081],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040455424,0.0002853567,0.0007772267,0.0007372405,0.000098813005,0.000015113536,0.00042251038,0.00041723708,0.0001642214],"category_scores_gemma":[0.00034092748,0.00026390314,0.000114403425,0.00023752394,0.00014732205,0.00016356498,0.0001947484,0.000450418,0.000035893718],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019287588,0.0014708317,0.73242694,0.00033041043,0.0000933843,0.00996979,0.0008403429,0.00004094191,0.20687637,0.00018565371,0.000094470466,0.045742117],"study_design_scores_gemma":[0.0032051913,0.00037798382,0.9508384,0.000058921134,0.00011384804,0.00018619608,0.00017169728,0.0010949528,0.04227613,0.001243976,0.00014381218,0.00028892804],"about_ca_topic_score_codex":0.0003762587,"about_ca_topic_score_gemma":0.0001353968,"teacher_disagreement_score":0.21841143,"about_ca_system_score_codex":0.000102446174,"about_ca_system_score_gemma":0.00023417445,"threshold_uncertainty_score":0.99998134},"labels":[],"label_agreement":null},{"id":"W2741722655","doi":"10.1158/1538-7445.am2017-3960","title":"Abstract 3960: Tumor cell drug resistance induced by the programmed death ligand 1 (PD-L1) immune checkpoint is associated with autophagy","year":2017,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Queen's University","funders":"","keywords":"Autophagy; Protein kinase B; PI3K/AKT/mTOR pathway; Cell biology; Cancer research; Programmed cell death; Signal transduction; MAPK/ERK pathway; Immune checkpoint; Cancer cell; Biology; Kinase; Cytotoxic T cell; Immune system; Chemistry; Cancer; Apoptosis; Immunology; Immunotherapy; Biochemistry","score_opus":0.06270573317777184,"score_gpt":0.3857097267998381,"score_spread":0.3230039936220663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2741722655","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9766008,0.0074670454,0.0000011967793,0.0068712197,0.000105305335,0.0013925507,0.000063198844,0.00008069894,0.007417929],"genre_scores_gemma":[0.9713908,0.00044937964,0.00001647723,0.00039895237,0.00020692496,0.0006228733,0.000030292644,0.000076942946,0.026807377],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99676234,0.0001311551,0.00035428026,0.0005575758,0.0012447272,0.00094995316],"domain_scores_gemma":[0.9971345,0.00018833693,0.00029920187,0.0014778174,0.0005538405,0.00034630726],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001509112,0.00027357542,0.0004442394,0.000086514316,0.0012125141,0.00030017787,0.0008218905,0.000122005586,0.0004654389],"category_scores_gemma":[0.00029324635,0.00017213872,0.00014387592,0.00026414785,0.0005020628,0.00016633394,0.00013617094,0.0011401857,0.000067767265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006995931,0.0020477993,0.00814503,0.0006155018,0.001324555,0.001255874,0.004793673,9.1540244e-7,0.91239786,0.00014177662,0.052767646,0.009513452],"study_design_scores_gemma":[0.0041389284,0.00020464568,0.19877331,0.0006149997,0.000067285735,0.000004364025,0.00024168886,0.000011261612,0.78387517,0.0002623687,0.011562135,0.00024381772],"about_ca_topic_score_codex":0.0016404723,"about_ca_topic_score_gemma":0.00027699157,"teacher_disagreement_score":0.19062828,"about_ca_system_score_codex":0.00043135945,"about_ca_system_score_gemma":0.0010954443,"threshold_uncertainty_score":0.9325801},"labels":[],"label_agreement":null},{"id":"W2743937374","doi":"10.1080/15548627.2017.1339002","title":"Discovery of pan autophagy inhibitors through a high-throughput screen highlights macroautophagy as an evolutionarily conserved process across 3 eukaryotic kingdoms","year":2017,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"University of California, San Diego; Jawaharlal Nehru Centre for Advanced Scientific Research; Wellcome Trust","keywords":"Autophagy; Biology; Vacuole; Cell biology; Saccharomyces cerevisiae; ATG8; Small molecule; Biochemistry; Yeast; Cytoplasm; Apoptosis","score_opus":0.024587689230510752,"score_gpt":0.34071778585665025,"score_spread":0.3161300966261395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2743937374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910059,0.002034445,0.00048071684,0.0010016742,0.0014347841,0.0014259752,0.00034441357,0.0005011483,0.0017709477],"genre_scores_gemma":[0.9920876,0.0003239515,0.0008896142,0.0010936587,0.0010905114,0.00015272116,0.00035366064,0.00019946788,0.0038088313],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"observational","domain_scores_codex":[0.9940625,0.00022339489,0.001423145,0.0015442611,0.0013410362,0.0014056845],"domain_scores_gemma":[0.99430954,0.00018234341,0.0013055657,0.0031501767,0.0005734197,0.0004789786],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0005272527,0.0009511279,0.0016716066,0.00017466769,0.0014162599,0.0003895082,0.0013732695,0.0006344663,0.00034634446],"category_scores_gemma":[0.00039424177,0.0008375409,0.00060854317,0.00037034875,0.0017478545,0.0030267197,0.00041583876,0.00061072764,0.00025022932],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.020441331,0.02322956,0.08910477,0.005388753,0.009972732,0.014133661,0.031539988,0.00036941827,0.27003837,0.5016031,0.007020961,0.027157342],"study_design_scores_gemma":[0.009453449,0.0017985781,0.50817275,0.000612088,0.00047445533,0.00033022318,0.00041224598,0.00047759726,0.45099652,0.024907041,0.0013680647,0.0009969744],"about_ca_topic_score_codex":0.0057302266,"about_ca_topic_score_gemma":0.00016325792,"teacher_disagreement_score":0.47669607,"about_ca_system_score_codex":0.00026088615,"about_ca_system_score_gemma":0.0011132746,"threshold_uncertainty_score":0.9998838},"labels":[],"label_agreement":null},{"id":"W2744171534","doi":"10.1016/j.chom.2017.07.005","title":"Innate Immunity to Intracellular Pathogens: Balancing Microbial Elimination and Inflammation","year":2017,"lang":"en","type":"review","venue":"Cell Host & Microbe","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Fonds de Recherche du Québec - Santé; Fonds de Recherche du Québec-Société et Culture; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Biology; Cell biology; Inflammasome; Compartmentalization (fire protection); Vacuole; Autophagy; Intracellular parasite; Intracellular; Innate immune system; Pathogen; Interferon; Inflammation; Immune system; Microbiology; Immunology; Biochemistry","score_opus":0.031548925094931804,"score_gpt":0.32099639619229176,"score_spread":0.28944747109735997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2744171534","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016475484,0.98072326,0.0000903274,0.00007822858,0.00035202628,0.0015935973,0.00009168472,0.00006554841,0.00052986667],"genre_scores_gemma":[0.0015220658,0.9951156,0.00038535596,0.000142044,0.0005063217,0.000058745925,0.0008448708,0.000093003495,0.0013320001],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99826413,0.00014766974,0.00062175636,0.00047202283,0.00014979209,0.00034461555],"domain_scores_gemma":[0.9982305,0.000058771595,0.00052626966,0.00083462044,0.0001341949,0.00021560554],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000428561,0.00048178673,0.001280335,0.00029535682,0.00028192485,0.00012018737,0.00025989398,0.00044099105,0.00008720375],"category_scores_gemma":[0.000096371,0.00043524415,0.00030176403,0.00011540646,0.00007908686,0.000116728675,0.0001848662,0.00050575787,0.00028641586],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038402806,0.00008283112,0.000004815257,0.012480215,0.000121640485,0.00012351671,0.000521537,1.1470226e-7,0.09466965,0.000010547526,0.0004945741,0.89145213],"study_design_scores_gemma":[0.0006340246,0.00010934607,0.00012007829,0.009021602,0.001065064,0.0001146471,0.000026550353,0.0000032540443,0.016770914,0.000007626044,0.9717127,0.0004142067],"about_ca_topic_score_codex":0.000026901616,"about_ca_topic_score_gemma":0.000004510443,"teacher_disagreement_score":0.9712181,"about_ca_system_score_codex":0.00018637849,"about_ca_system_score_gemma":0.0003019219,"threshold_uncertainty_score":0.9998099},"labels":[],"label_agreement":null},{"id":"W2744720426","doi":"10.1139/cjpp-2016-0676","title":"Hydroxytyrosol regulates the autophagy of vascular adventitial fibroblasts through the SIRT1-mediated signaling pathway","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Natural Science Foundation of Shaanxi Province; National Natural Science Foundation of China","keywords":"Autophagy; PI3K/AKT/mTOR pathway; Sirtuin 1; Cell biology; Cancer research; Protein kinase B; Biology; ATG5; Proinflammatory cytokine; Downregulation and upregulation; Inflammation; Signal transduction; Immunology; Apoptosis; Biochemistry; Gene","score_opus":0.014276577632516585,"score_gpt":0.2783252189252755,"score_spread":0.2640486412927589,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2744720426","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919057,0.0046098297,0.000009396994,0.0022745614,0.00079657027,0.00019072063,0.000022461667,0.0000037023112,0.00018706228],"genre_scores_gemma":[0.9973595,0.00028311688,0.000018415263,0.0015451781,0.00069543987,0.0000051795737,0.000005807848,0.00001312485,0.000074238036],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989275,0.0002194874,0.00033372696,0.0001328478,0.00009026789,0.00029618994],"domain_scores_gemma":[0.998639,0.00023856912,0.000469694,0.0002631539,0.00015245628,0.0002371569],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00028881448,0.00014076043,0.0003892483,0.000058752765,0.0006012896,0.000013516301,0.00036827242,0.00013602986,0.0012902956],"category_scores_gemma":[0.00008193835,0.00008008724,0.00020232012,0.00005002892,0.0011397237,0.00010810417,0.000028167191,0.00039789558,0.000005514047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029036467,0.000043220713,0.00033194677,0.00007330109,0.00087003777,0.00021102115,0.00110664,0.00016042005,0.9941676,0.00046749966,0.001792266,0.00048567733],"study_design_scores_gemma":[0.0031545362,0.0007671809,0.026879944,0.00009067137,0.00049977563,0.00027297204,0.00014702053,0.00024282756,0.94936967,0.006423942,0.012018924,0.00013250901],"about_ca_topic_score_codex":0.00053024886,"about_ca_topic_score_gemma":0.00016213326,"teacher_disagreement_score":0.04479791,"about_ca_system_score_codex":0.000023583712,"about_ca_system_score_gemma":0.0007547721,"threshold_uncertainty_score":0.99962264},"labels":[],"label_agreement":null},{"id":"W2749499656","doi":"10.1080/15548627.2017.1339001","title":"ESRRA (estrogen-related receptor α) is a key coordinator of transcriptional and post-translational activation of autophagy to promote innate host defense","year":2017,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Cell biology; ATG5; Innate immune system; BECN1; Sirtuin 1; BAG3; Autophagosome; ATG16L1; Effector; Receptor; Downregulation and upregulation; Gene; Biochemistry; Apoptosis","score_opus":0.01407810496215887,"score_gpt":0.278473314803675,"score_spread":0.2643952098415161,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2749499656","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99418676,0.0008196822,0.00016720752,0.0030300259,0.00017460086,0.00071470527,0.00028738877,0.00005358937,0.00056602375],"genre_scores_gemma":[0.9968344,0.000058642432,0.001637487,0.0005220284,0.00006316507,0.000033306245,0.00009780852,0.00003930702,0.00071384775],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99830943,0.000044075252,0.00055625004,0.0003833118,0.00044622342,0.00026070324],"domain_scores_gemma":[0.99843657,0.000048075126,0.0003496258,0.00050886406,0.0004201453,0.00023671593],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00021111827,0.00024573528,0.00048705863,0.0002065303,0.0001907054,0.000025562429,0.00019449402,0.0002050877,0.0009557125],"category_scores_gemma":[0.00013496757,0.0002339927,0.00018986453,0.00015378461,0.00023674482,0.00029006766,0.000034625624,0.00017852127,0.000028813158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014859042,0.0005217008,0.0034823911,0.00021171378,0.0005289043,0.000018398288,0.0029324915,0.000005939828,0.95216244,0.028272185,0.00016838957,0.010209553],"study_design_scores_gemma":[0.0034726767,0.0006534143,0.46607783,0.00022758044,0.00013727584,0.00002591206,0.000038282415,0.00027883763,0.52491456,0.0010611487,0.0029144525,0.00019805056],"about_ca_topic_score_codex":0.000109415894,"about_ca_topic_score_gemma":0.000001689908,"teacher_disagreement_score":0.46259543,"about_ca_system_score_codex":0.000034906025,"about_ca_system_score_gemma":0.00027309984,"threshold_uncertainty_score":0.99995756},"labels":[],"label_agreement":null},{"id":"W2752326209","doi":"10.1080/15548627.2015.1100356","title":"Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)","year":2016,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5992,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; Sunnybrook Hospital; University of Calgary; Concordia University; University of Waterloo; Canada's Michael Smith Genome Sciences Centre; Terry Fox Research Institute; Institute for Research in Immunology and Cancer; Manitoba Health; York University; Innovation and Economic Development Trois Rivières; BC Cancer Agency; University Health Network; University of Alberta; University of British Columbia; CancerCare Manitoba; University of Manitoba; Prevention of Organ Failure; Université Laval; Centre hospitalier universitaire de Québec; Jewish General Hospital; Simon Fraser University; Dalhousie University; University of Ottawa; McGill University; Université du Québec à Trois-Rivières; McGill University Health Centre; Lunenfeld-Tanenbaum Research Institute; St. Paul's Hospital; Western University; Hospital for Sick Children; Royal Military College of Canada; Université de Montréal; Montreal Neurological Institute and Hospital; Université de Sherbrooke; Université du Québec à Montréal; McMaster University; University of Toronto; Sunnybrook Health Science Centre; Institute of Infection and Immunity","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute on Minority Health and Health Disparities; National Institute of Environmental Health Sciences; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Drug Abuse; National Heart, Lung, and Blood Institute; National Institute on Alcohol Abuse and Alcoholism; National Eye Institute; National Center for Complementary and Integrative Health; National Institute for Health and Care Research; National Institute on Aging; National Cancer Institute; Wellcome Trust; Cancer Research UK; Biotechnology and Biological Sciences Research Council; National Center for Research Resources; National Institute of Allergy and Infectious Diseases; Medical Research Council; Brain Tumour Charity; National Institutes of Health; U.S. Department of Veterans Affairs; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Novo Nordisk Fonden; Doris Duke Charitable Foundation; National Institute of Neurological Disorders and Stroke; National Centre for the Replacement, Refinement and Reduction of Animals in Research; Parkinson's UK; Lundbeckfonden; Action Medical Research; National Institute of General Medical Sciences","keywords":"Autophagy; Autophagosome; Biology; Cell biology; Vacuole; Phagosome; ATG8; Multicellular organism; Biogenesis; Intracellular; Cell; Biochemistry; Cytoplasm","score_opus":0.11117206901739356,"score_gpt":0.3736674081243194,"score_spread":0.26249533910692585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2752326209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.63159,0.004188719,0.35370982,0.0059259743,0.0019206883,0.0021966244,0.00022685844,0.00016915145,0.00007216436],"genre_scores_gemma":[0.98843926,0.00040497188,0.00775702,0.000634331,0.0009835785,0.00033655303,0.0000152093035,0.000033902423,0.0013951837],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990284,0.000021326698,0.00037548406,0.00022046837,0.00015864297,0.00019569458],"domain_scores_gemma":[0.99774116,0.0011841095,0.0001506777,0.00028215972,0.00056652864,0.00007538085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002555446,0.00014196704,0.00025112595,0.000066449655,0.00010262864,0.000021373853,0.00009011761,0.000082602084,0.0000398896],"category_scores_gemma":[0.0010827959,0.00007840852,0.00015401532,0.000065051805,0.00009898933,0.00024278965,0.000024006578,0.000039706083,0.000003813397],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022734983,0.00025155855,0.0028794496,0.00042542297,0.0008570867,0.00000955197,0.0007080603,0.000044750093,0.18140177,0.011860472,0.021819888,0.7774685],"study_design_scores_gemma":[0.010998755,0.0014082366,0.10020403,0.0009804983,0.00084728317,0.0000461818,0.00020489383,0.024892207,0.7861649,0.011349651,0.06248552,0.00041783243],"about_ca_topic_score_codex":0.000012372547,"about_ca_topic_score_gemma":0.0000011024124,"teacher_disagreement_score":0.7770507,"about_ca_system_score_codex":0.00003186487,"about_ca_system_score_gemma":0.00006993046,"threshold_uncertainty_score":0.31974068},"labels":[],"label_agreement":null},{"id":"W2757575073","doi":"10.1530/jme-17-0096","title":"Adiponectin improves insulin sensitivity via activation of autophagic flux","year":2017,"lang":"en","type":"article","venue":"Journal of Molecular Endocrinology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Insulin resistance; Adiponectin; Unfolded protein response; ATF6; Endoplasmic reticulum; Internal medicine; Skeletal muscle; Chemistry; Endocrinology; Insulin; Cell biology; ATG5; Biology; Medicine; Biochemistry; Apoptosis","score_opus":0.013287964113507059,"score_gpt":0.294337904835925,"score_spread":0.2810499407224179,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2757575073","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927021,0.0006964635,0.0041202344,0.0012922647,0.0002614886,0.00012177569,0.0000016489369,0.000010946678,0.00079305435],"genre_scores_gemma":[0.99857324,0.00011209236,0.0006908242,0.00036391942,0.00015185839,0.0000014937508,0.0000022897875,0.000016657565,0.00008761501],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989424,0.00010982259,0.00038982523,0.00012505033,0.00022037925,0.00021255027],"domain_scores_gemma":[0.99833894,0.00005805331,0.00081562385,0.0004154059,0.00026781773,0.000104156745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017894109,0.00012486715,0.00044313972,0.0001694718,0.00008273946,0.00001078495,0.00013680167,0.00008900295,0.00006035053],"category_scores_gemma":[0.00040526807,0.00010540912,0.00022783244,0.000037846225,0.0001536586,0.0001290556,0.000052030373,0.00031061395,0.000008192402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006268082,0.0002386427,0.00083343073,0.000034097055,0.00037648555,0.001880832,0.000053223113,0.000009477598,0.9460052,0.00053885975,0.000053137435,0.04934979],"study_design_scores_gemma":[0.0024002935,0.00070070766,0.13165583,0.00005411422,0.00014825563,0.0017193799,0.000019060431,0.00015818866,0.8612445,0.001365459,0.00046268557,0.000071539296],"about_ca_topic_score_codex":0.000032350792,"about_ca_topic_score_gemma":9.652404e-7,"teacher_disagreement_score":0.1308224,"about_ca_system_score_codex":0.000042512762,"about_ca_system_score_gemma":0.00014993541,"threshold_uncertainty_score":0.4298459},"labels":[],"label_agreement":null},{"id":"W2757958974","doi":"10.1080/15548627.2017.1356977","title":"Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition","year":2017,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":220,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"","keywords":"Ezetimibe; Autophagy; TFEB; AMPK; Steatohepatitis; Inflammasome; Biology; Cell biology; Steatosis; Cancer research; Protein kinase A; Fatty liver; Endocrinology; Internal medicine; Inflammation; Statin; Kinase; Biochemistry; Immunology; Medicine; Apoptosis","score_opus":0.015660574141344658,"score_gpt":0.2723786838360639,"score_spread":0.25671810969471925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2757958974","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99620825,0.00030273187,0.00033219237,0.00072016,0.00013066985,0.00118386,0.000046807214,0.00022104091,0.0008542885],"genre_scores_gemma":[0.99743795,0.0001471868,0.00049992086,0.00033479734,0.00018984197,0.00015539117,0.00027705336,0.00006969729,0.0008881538],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997915,0.00010465461,0.00057804707,0.0005193489,0.00046669188,0.00041624397],"domain_scores_gemma":[0.99771553,0.0000952395,0.000698511,0.0009201805,0.0003006793,0.00026988497],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023094565,0.00037938554,0.0006429008,0.0002774903,0.000376399,0.0000904276,0.0001794054,0.000318639,0.0004806958],"category_scores_gemma":[0.0003918292,0.0003535844,0.0001365629,0.00022506539,0.0003886654,0.000712681,0.00011729334,0.0003078434,0.000074269985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052529346,0.00032194905,0.0029015804,0.00022784028,0.00018926061,0.000101439604,0.00036894862,0.0000044431895,0.98154354,0.00049594324,0.00017180305,0.013147938],"study_design_scores_gemma":[0.0030866321,0.00038280294,0.22795035,0.00036468252,0.00007834856,0.00001755103,0.000022231896,0.0004155153,0.76503,0.0012753536,0.0011170488,0.0002594508],"about_ca_topic_score_codex":0.00047864325,"about_ca_topic_score_gemma":0.000018730785,"teacher_disagreement_score":0.22504878,"about_ca_system_score_codex":0.000103626684,"about_ca_system_score_gemma":0.00018851881,"threshold_uncertainty_score":0.99989164},"labels":[],"label_agreement":null},{"id":"W2760657482","doi":"10.1080/15548627.2017.1370171","title":"Oncogenic RAS-induced downregulation of ATG12 is required for survival of malignant intestinal epithelial cells","year":2017,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"ATG12; Biology; ATG5; Autophagy; Cell biology; Cancer research; Effector; Small GTPase; Cancer cell; Downregulation and upregulation; Cancer; Apoptosis; Signal transduction; Biochemistry; Gene; Genetics","score_opus":0.05046315864514727,"score_gpt":0.33463004922067535,"score_spread":0.2841668905755281,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2760657482","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965253,0.0001556984,0.0010941926,0.0002323535,0.0004468992,0.000602603,0.00010666601,0.00003297088,0.0008032999],"genre_scores_gemma":[0.99729866,0.000033208256,0.0010282792,0.00009591421,0.00029112457,0.000026693027,0.000028740795,0.000032025364,0.0011653814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99861926,0.00003780893,0.00050797756,0.00028109024,0.00030035482,0.000253487],"domain_scores_gemma":[0.99810493,0.000120348224,0.00057942426,0.000815752,0.00026264632,0.000116891],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032866787,0.00018065886,0.0005305365,0.000085405896,0.00012538317,0.000013178355,0.00025916012,0.00013084963,0.000282919],"category_scores_gemma":[0.00016336596,0.00015576766,0.00030457482,0.00005807839,0.00015710045,0.00012219338,0.00005586546,0.0000742826,0.000026499092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009811163,0.00023486727,0.0005495558,0.00016832203,0.00017192477,0.00001599374,0.0002384853,0.0000022805684,0.98373604,0.0015726547,0.00023031486,0.012098454],"study_design_scores_gemma":[0.003476603,0.0007204025,0.09791331,0.00013314432,0.00020217808,0.000009688428,0.000029233055,0.0006539286,0.89434606,0.0019374184,0.00045118105,0.00012683694],"about_ca_topic_score_codex":0.00011646993,"about_ca_topic_score_gemma":0.0000030589497,"teacher_disagreement_score":0.097363755,"about_ca_system_score_codex":0.000038043992,"about_ca_system_score_gemma":0.00023646912,"threshold_uncertainty_score":0.6352021},"labels":[],"label_agreement":null},{"id":"W2762660708","doi":"10.1201/9781315152363-6","title":"Nanoparticles and Viruses as Mitophagy Inducers in Immune Cells","year":2017,"lang":"en","type":"book-chapter","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"","keywords":"Mitophagy; Autophagy; Cell biology; Mitochondrion; Organelle; Immune system; Chemistry; Nanotechnology; Biology; Materials science; Biochemistry; Apoptosis; Immunology","score_opus":0.028384847033853345,"score_gpt":0.2937163636686023,"score_spread":0.26533151663474897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2762660708","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.36493874,0.009082528,3.3207775e-7,0.0001674232,0.00020491502,0.0003591339,0.000009207982,0.000049639242,0.6251881],"genre_scores_gemma":[0.42341545,0.0025387735,0.000046242614,0.0011900259,0.00016070619,0.00000922899,0.00000845849,0.000056208202,0.5725749],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990834,0.000007497354,0.00026013472,0.00029079986,0.00017335625,0.0001847928],"domain_scores_gemma":[0.99917,0.00003729727,0.000121817684,0.0004970862,0.000028252374,0.00014552842],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007231374,0.00025023392,0.00046430883,0.00012457551,0.00005951247,0.00003021381,0.000105212435,0.0002789084,0.0020802317],"category_scores_gemma":[0.000014195777,0.00020531287,0.000100514946,0.0000065086138,0.0001742898,0.00006359267,0.00005859159,0.00024261612,0.00039008717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022319024,0.00054837775,0.0015830597,0.000653203,0.0017973499,0.0061463686,0.0013326958,9.3336234e-7,0.717704,0.13097548,0.0059547834,0.13107185],"study_design_scores_gemma":[0.004574021,0.00060443336,0.0070520174,0.0010769246,0.00032135597,0.000084631974,0.00006979941,0.0000059892714,0.72610223,0.03141873,0.22793949,0.00075037853],"about_ca_topic_score_codex":0.00016873756,"about_ca_topic_score_gemma":0.00002492794,"teacher_disagreement_score":0.22198471,"about_ca_system_score_codex":0.000034757377,"about_ca_system_score_gemma":0.00012957555,"threshold_uncertainty_score":0.998832},"labels":[],"label_agreement":null},{"id":"W2763217028","doi":"10.1111/bpa.12567","title":"Downregulated apoptosis and autophagy after anti‐Aβ immunotherapy in Alzheimer's disease","year":2017,"lang":"en","type":"article","venue":"Brain Pathology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; Fondation Philippe Chatrier; Fondation Philippe Wiener - Maurice Anspach; University of Southampton; Medical Research Council Canada; University Hospital Southampton NHS Foundation Trust; Johns Hopkins University","keywords":"Autophagy; Apoptosis; Immunotherapy; Disease; Medicine; Alzheimer's disease; Cancer research; Immunology; Biology; Pathology; Immune system; Genetics","score_opus":0.013803748526230552,"score_gpt":0.2958427992337521,"score_spread":0.28203905070752155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2763217028","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9865591,0.0077526956,0.000023075503,0.0045478367,0.00017671763,0.00039279633,0.000023889068,0.00006746579,0.0004564103],"genre_scores_gemma":[0.99474955,0.0004859102,0.00017093813,0.0040411307,0.000111016765,0.00009489014,0.00002362749,0.00003788318,0.00028505237],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987489,0.00010235016,0.00025246158,0.0004231133,0.00011944223,0.00035373296],"domain_scores_gemma":[0.99872285,0.000054819768,0.0001132465,0.0008633128,0.00003310287,0.00021266287],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020221136,0.00021498451,0.00040098894,0.00014478147,0.00015142877,0.000041227053,0.00016647164,0.00016680713,0.00036034617],"category_scores_gemma":[0.00009386852,0.00018758394,0.00009679427,0.00005611038,0.00037806178,0.0001286373,0.00007733955,0.00016730312,0.0000445057],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008337872,0.0017544706,0.6003133,0.0001372008,0.0008779083,0.013698704,0.0023968376,0.000006578866,0.19143462,0.0025034482,0.0020115199,0.17652753],"study_design_scores_gemma":[0.003707949,0.00013558334,0.9872287,0.000058700472,0.00008185924,0.000086161126,0.000016901047,0.00009113307,0.0054761386,0.0013358393,0.0015862649,0.00019479239],"about_ca_topic_score_codex":0.000028037965,"about_ca_topic_score_gemma":0.0000040583245,"teacher_disagreement_score":0.3869154,"about_ca_system_score_codex":0.000017813862,"about_ca_system_score_gemma":0.00007723613,"threshold_uncertainty_score":0.7649451},"labels":[],"label_agreement":null},{"id":"W2765788534","doi":"10.1007/7651_2017_84","title":"Simultaneous Detection of Autophagy and Epithelial to Mesenchymal Transition in the Non-small Cell Lung Cancer Cells","year":2017,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"","keywords":"Autophagy; Epithelial–mesenchymal transition; Cell biology; Mesenchymal stem cell; Carcinogenesis; Phenotype; Cell; Biology; Cancer cell; Cell growth; Apoptosis; Cancer research; Cancer; Metastasis; Gene; Biochemistry; Genetics","score_opus":0.012712958115106539,"score_gpt":0.3776871685013671,"score_spread":0.36497421038626054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765788534","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.69126385,0.00052336,0.30739707,0.00017892625,0.00012388985,0.00038612145,0.0000088736615,0.000004460537,0.000113404465],"genre_scores_gemma":[0.93675303,0.00014005558,0.062342923,0.00062037277,0.000049370265,0.000060185226,0.000002242136,0.000011470891,0.00002036296],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880904,0.0004932596,0.00021327581,0.000239911,0.000056640074,0.00018789707],"domain_scores_gemma":[0.9993236,0.00017898735,0.00008488178,0.00033460482,0.000031246567,0.000046698497],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000697928,0.00011681784,0.00027673747,0.00011526238,0.000052962427,0.0000078541125,0.00014711039,0.00015576449,0.000013883853],"category_scores_gemma":[0.00011786883,0.00008679354,0.0000605933,0.00008091264,0.0001005769,0.00001398294,0.00002750659,0.00017315279,6.904899e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021463292,0.000070801376,0.00040319245,0.000052599167,0.000018674169,0.000121192475,0.0011406516,0.0002461375,0.9642036,0.000031316642,5.1346274e-7,0.0334967],"study_design_scores_gemma":[0.0011891753,0.00030880608,0.0069569997,0.000037373968,0.000054638014,0.000011020513,0.00007241697,0.006386111,0.9842933,0.000500361,0.000103136066,0.00008665395],"about_ca_topic_score_codex":0.0005081722,"about_ca_topic_score_gemma":0.00007889522,"teacher_disagreement_score":0.24548914,"about_ca_system_score_codex":0.000027396445,"about_ca_system_score_gemma":0.000043569053,"threshold_uncertainty_score":0.35393378},"labels":[],"label_agreement":null},{"id":"W2765956337","doi":"10.1016/j.bbamcr.2017.10.014","title":"Autophagy activation is required for influenza A virus-induced apoptosis and replication","year":2017,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research Manitoba; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Autophagy; Apoptosis; ATG5; Biology; Viral replication; Cell biology; Virus; Programmed cell death; Influenza A virus; Flow cytometry; Virology; Molecular biology","score_opus":0.10688254861946583,"score_gpt":0.4258476257877506,"score_spread":0.31896507716828476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765956337","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904985,0.000111785484,0.00015872871,0.0053697634,0.000052631276,0.0017828527,0.000048403846,0.00008226993,0.0018950977],"genre_scores_gemma":[0.9961257,0.00024065834,0.0006799908,0.0017338173,0.000189687,0.00040790348,0.00010596714,0.00009078178,0.00042552527],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99704564,0.00018149208,0.00036174984,0.0010238626,0.00077677396,0.0006104853],"domain_scores_gemma":[0.99630356,0.00016379984,0.00028096468,0.0024292378,0.00047928668,0.00034313946],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007667245,0.0003021176,0.00039484343,0.0002829442,0.0007710709,0.00030392563,0.00051456055,0.00027815806,0.00002944258],"category_scores_gemma":[0.00047589035,0.0002863883,0.00023187412,0.00024987487,0.00031647642,0.00031601964,0.00026180208,0.0004184885,0.000039747432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009626045,0.00040477523,0.000004802927,0.00017481514,0.00015419764,0.000005298877,0.00041061852,9.695518e-8,0.9922843,0.0005298485,0.0010908112,0.003977821],"study_design_scores_gemma":[0.0023129578,0.0007187573,0.004477481,0.00010970404,0.00008993369,0.0000017657628,0.000054097625,0.00037524645,0.98827064,0.0015572916,0.0017640812,0.0002680329],"about_ca_topic_score_codex":0.00013979239,"about_ca_topic_score_gemma":6.943577e-7,"teacher_disagreement_score":0.005627202,"about_ca_system_score_codex":0.00011802417,"about_ca_system_score_gemma":0.00035048573,"threshold_uncertainty_score":0.9999588},"labels":[],"label_agreement":null},{"id":"W2765978280","doi":"10.1016/j.bbrc.2017.10.110","title":"Dihydroceramide is a key metabolite that regulates autophagy and promotes fibrosis in hepatic steatosis model","year":2017,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"National Center for Inter-University Research Facilities, Seoul National University","keywords":"Autophagy; Sphingolipid; Steatosis; Hepatic stellate cell; Lipid metabolism; Lipid droplet; Cell biology; Sphingosine; Biology; Fatty liver; Flux (metallurgy); Nonalcoholic fatty liver disease; Endocrinology; Cancer research; Chemistry; Internal medicine; Biochemistry; Medicine; Disease; Apoptosis; Receptor","score_opus":0.10453772877779838,"score_gpt":0.39898100168766465,"score_spread":0.29444327290986627,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765978280","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9842247,0.0038934776,0.0000069648445,0.010901482,0.000004545505,0.00038446402,0.000047198926,0.000029933917,0.000507285],"genre_scores_gemma":[0.9922534,0.005570261,0.001372702,0.0001801694,0.000034641966,0.00012390946,0.000035318215,0.000017525701,0.0004120735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985963,0.00010311417,0.00020196864,0.00035708927,0.00038046413,0.00036104958],"domain_scores_gemma":[0.9975092,0.000294331,0.000057584173,0.0016878551,0.0001305667,0.00032048882],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029673142,0.00015928796,0.00033282975,0.00010943155,0.0005796855,0.00015943868,0.0005580028,0.00012945867,0.000012247798],"category_scores_gemma":[0.00034603855,0.00012361385,0.000083587576,0.00015857581,0.0014467089,0.00016246286,0.0007239738,0.0004048682,0.000007911343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020515428,0.0009218215,0.005788459,0.00017904415,0.000099401645,0.000004552338,0.00062599377,1.250221e-7,0.9807085,0.004584097,0.00024172323,0.006641123],"study_design_scores_gemma":[0.0013372453,0.00015468852,0.121274725,0.00032647894,0.00008229321,0.0000052646324,0.000075754724,0.07156391,0.77941525,0.02507775,0.0004530468,0.00023361843],"about_ca_topic_score_codex":0.0002634592,"about_ca_topic_score_gemma":0.000006436353,"teacher_disagreement_score":0.20129329,"about_ca_system_score_codex":0.000037794616,"about_ca_system_score_gemma":0.00009061538,"threshold_uncertainty_score":0.5330459},"labels":[],"label_agreement":null},{"id":"W2766026926","doi":"10.1016/j.jcjd.2017.08.198","title":"Autophagy and Lysosomal Function Protect β-Cells under Hypoxic Stress","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autophagy; Medicine; Cell biology; Hypoxia (environmental); Lipotoxicity; Autophagosome; Homeostasis; Lysosome; Islet; Programmed cell death; Diabetes mellitus; Biology; Apoptosis; Endocrinology; Biochemistry; Chemistry; Insulin resistance","score_opus":0.013808040562090035,"score_gpt":0.23704211718092402,"score_spread":0.223234076618834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2766026926","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951399,0.0027941794,0.000017093209,0.0008097475,0.000437651,0.00013604909,0.00001713179,0.0000059358304,0.00064229855],"genre_scores_gemma":[0.99862033,0.000018263432,0.000057658883,0.0005213951,0.000390581,0.0000027656831,0.0000017070921,0.000017209673,0.00037005826],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99929774,0.000025058815,0.00018865008,0.000103356986,0.00012454961,0.00026066575],"domain_scores_gemma":[0.9986795,0.000023597522,0.00021692512,0.0002420633,0.0001066766,0.0007312126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013115558,0.00011069378,0.00023563266,0.0001548321,0.00029335817,0.00011257311,0.00012814831,0.000079283076,0.00023395254],"category_scores_gemma":[0.00007084581,0.000091341244,0.00008901806,0.000027450747,0.00016297538,0.00019487555,0.000008039801,0.00018355066,0.000010395316],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013498674,0.00019664527,0.8080471,0.000389506,0.0016990482,0.00068861153,0.0004909917,0.000051669565,0.09200339,0.00139292,0.0036080668,0.09129706],"study_design_scores_gemma":[0.0016933876,0.00058474764,0.9484792,0.00024836624,0.00019801098,0.000018931063,0.00007635086,0.00006134958,0.045027547,0.0017791656,0.0017071108,0.00012586458],"about_ca_topic_score_codex":0.00021316996,"about_ca_topic_score_gemma":0.0006326876,"teacher_disagreement_score":0.14043206,"about_ca_system_score_codex":0.000059173963,"about_ca_system_score_gemma":0.00065054937,"threshold_uncertainty_score":0.37247878},"labels":[],"label_agreement":null},{"id":"W2766551661","doi":"10.1016/j.exger.2017.10.018","title":"The effect of ARC ablation on skeletal muscle morphology, function, and apoptotic signaling during aging","year":2017,"lang":"en","type":"article","venue":"Experimental Gerontology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Skeletal muscle; Arc (geometry); XIAP; Internal medicine; Biology; Endocrinology; Apoptosis; Mitochondrion; Cell biology; Myocyte; Muscle atrophy; Sarcopenia; Caspase; Chemistry; Biochemistry; Programmed cell death; Medicine","score_opus":0.01616738683556253,"score_gpt":0.31459482211825596,"score_spread":0.29842743528269344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2766551661","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99616206,0.0022623155,0.000026768495,0.00017914576,0.00029088947,0.00022764519,7.902307e-7,0.000023092745,0.0008272715],"genre_scores_gemma":[0.99960434,0.000017964276,0.000026897571,0.0000557562,0.00012310693,0.000028818256,0.0000040819236,0.000012215506,0.00012679592],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993335,0.00007108717,0.00014879978,0.00018283325,0.000090979396,0.00017278701],"domain_scores_gemma":[0.99940825,0.0000991131,0.00012638852,0.00029987897,0.000011818253,0.000054544882],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013304713,0.000111304624,0.00020194757,0.00003094113,0.00046817132,0.000016054732,0.00007467059,0.00006195095,0.0000784325],"category_scores_gemma":[0.000037346003,0.000077468474,0.000059251197,0.000011987396,0.00029158898,0.00006064599,0.000039210518,0.00009457666,0.000008944391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00088329834,0.0000718481,0.017318558,0.000031552263,0.00012538818,0.000029593573,0.00031603855,0.000005052112,0.9769481,0.00047708472,0.000023022756,0.0037704872],"study_design_scores_gemma":[0.002626854,0.0014000891,0.40724096,0.000034583714,0.00004397598,0.00004228186,0.00018493476,0.00008276336,0.58814865,0.00006761632,0.00005820862,0.00006907759],"about_ca_topic_score_codex":0.000036851412,"about_ca_topic_score_gemma":0.000002125234,"teacher_disagreement_score":0.3899224,"about_ca_system_score_codex":0.000033537795,"about_ca_system_score_gemma":0.000008385511,"threshold_uncertainty_score":0.36008427},"labels":[],"label_agreement":null},{"id":"W2766965062","doi":"10.3233/bpl-170047","title":"Autophagy and Adult Neurogenesis: Discoveries Made Half a Century Ago Yet in their Infancy of being Connected","year":2017,"lang":"en","type":"review","venue":"Brain Plasticity","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Heart and Stroke Foundation; Hospital for Sick Children; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Neurogenesis; Autophagy; Neural stem cell; Neuroscience; Biology; Mechanism (biology); Stem cell; Cell biology; Genetics","score_opus":0.03710183194803615,"score_gpt":0.3285107749963669,"score_spread":0.29140894304833076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2766965062","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07567771,0.922314,0.000024110283,0.00007400139,0.00023103281,0.0009848591,0.0003448097,0.00006289327,0.00028658807],"genre_scores_gemma":[0.033461746,0.96566087,0.000039112743,0.00021147383,0.00013676714,0.00008896101,0.0001803304,0.00007104653,0.00014970696],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.997921,0.00019898744,0.00074257556,0.0005263504,0.0002356372,0.00037548368],"domain_scores_gemma":[0.99769896,0.0009656416,0.0005737617,0.00049708603,0.00007457852,0.00018998755],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012875703,0.00052824133,0.0022275418,0.00025255122,0.00009971448,0.000040814022,0.00025547025,0.000346108,0.00006446933],"category_scores_gemma":[0.0015331276,0.00039749642,0.00033447964,0.00017667623,0.00027002336,0.00012134851,0.00014767628,0.0004098804,0.000006540387],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006687657,0.0008298459,0.0018018591,0.06244761,0.0015524229,0.0011079144,0.0016727194,0.0000012363248,0.00021328477,0.006431827,0.00050397025,0.92276853],"study_design_scores_gemma":[0.006330829,0.0007605111,0.056534845,0.08470111,0.0029892225,0.00053972827,0.0002241738,0.0001770309,0.00086726394,0.001239661,0.8439874,0.0016482217],"about_ca_topic_score_codex":0.0000755,"about_ca_topic_score_gemma":0.000042179872,"teacher_disagreement_score":0.92112035,"about_ca_system_score_codex":0.000038678063,"about_ca_system_score_gemma":0.00046676674,"threshold_uncertainty_score":0.9998477},"labels":[],"label_agreement":null},{"id":"W2767634639","doi":"10.1038/cdd.2017.166","title":"TM9SF4 is a novel factor promoting autophagic flux under amino acid starvation","year":2017,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of California, Davis; Chinese University of Hong Kong; Wellcome Trust; University of Hong Kong; Institute of Genetics; National Natural Science Foundation of China; City University of Hong Kong; National Science Foundation","keywords":"Autophagy; Cell biology; Programmed cell death; Autophagosome; PI3K/AKT/mTOR pathway; Gene knockdown; BAG3; Bafilomycin; Lysosome; Biology; HEK 293 cells; Endosome; Chemistry; Apoptosis; Signal transduction; Intracellular; Biochemistry; Receptor","score_opus":0.0357473773933749,"score_gpt":0.28314426064641973,"score_spread":0.24739688325304482,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2767634639","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99266046,0.00030504487,0.0051038777,0.00027764402,0.00015840755,0.00031364884,0.00002250773,0.000057999605,0.0011003964],"genre_scores_gemma":[0.9969658,0.00006511916,0.00022480737,0.0004107819,0.00015415484,0.000014354122,0.00015213588,0.000018542736,0.0019942976],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99917966,0.000011659066,0.00017584054,0.00025595023,0.00018860082,0.00018826697],"domain_scores_gemma":[0.9992676,0.000013631455,0.00018517785,0.00032995362,0.00006279403,0.00014083723],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000044735916,0.000152201,0.00018482422,0.00005995186,0.0003408199,0.00013262803,0.00007062041,0.00010097786,0.00036613943],"category_scores_gemma":[0.000025059162,0.00012725858,0.00006479147,0.000022764656,0.000030029603,0.00022589914,0.000033575132,0.000096715135,0.000030927917],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019146662,0.0007419919,0.24082579,0.0003885691,0.00014941642,0.0000087006265,0.002020415,6.9868156e-7,0.7364844,0.0012894791,0.00018804855,0.017711],"study_design_scores_gemma":[0.0019020557,0.00009689691,0.8462653,0.00004287834,0.0000904563,0.0000025251325,0.00003065636,0.0032192848,0.14729013,0.00083763275,0.00010850465,0.00011364743],"about_ca_topic_score_codex":0.00002412246,"about_ca_topic_score_gemma":0.0000021905337,"teacher_disagreement_score":0.60543954,"about_ca_system_score_codex":0.000036959806,"about_ca_system_score_gemma":0.000042132608,"threshold_uncertainty_score":0.5189454},"labels":[],"label_agreement":null},{"id":"W2769016235","doi":"10.1007/978-981-10-6674-0_10","title":"Beyond Deubiquitylation: USP30-Mediated Regulation of Mitochondrial Homeostasis","year":2017,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Parkin; Mitophagy; Deubiquitinating enzyme; PINK1; MFN2; mitochondrial fusion; Ubiquitin; Ubiquitin ligase; Cell biology; Mitochondrion; Mitochondrial fission; MFN1; DNAJA3; Biology; Autophagy; Chemistry; Mitochondrial DNA; Genetics; Gene; Apoptosis","score_opus":0.08929967664831516,"score_gpt":0.4542865319204253,"score_spread":0.3649868552721101,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2769016235","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00071268174,0.99534005,0.000011304964,0.000065118686,0.00079179375,0.00076296413,0.000032073913,0.000018130202,0.0022658964],"genre_scores_gemma":[0.0045526475,0.99335676,0.00022890382,0.00010613806,0.0007521663,0.00009501345,0.00081821124,0.000023720477,0.000066428445],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984053,0.000111537745,0.00073176285,0.00041485153,0.00012410838,0.00021248955],"domain_scores_gemma":[0.9986594,0.00023094518,0.0005781283,0.00038253973,0.0000404792,0.0001085624],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000120590375,0.00032471106,0.0018895225,0.00030455712,0.00006150871,0.0000032397375,0.00013997726,0.00035740816,0.0002327174],"category_scores_gemma":[0.0001465219,0.00021828584,0.00014619167,0.00014639003,0.00074319955,0.00012728751,0.000064017164,0.00020694312,0.0000056109334],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020980672,0.00014531396,0.00010659902,0.0021727583,0.00011508637,0.000018431178,0.00019437015,3.9965045e-8,0.0009905664,0.0008279771,0.000084985324,0.99513406],"study_design_scores_gemma":[0.0025118734,0.0013746663,0.00008399568,0.0065376,0.00031823796,0.00006936104,0.00014294226,0.0000027923575,0.0008005542,0.0007853868,0.98715216,0.00022044912],"about_ca_topic_score_codex":0.000021720396,"about_ca_topic_score_gemma":0.000005720984,"teacher_disagreement_score":0.99491364,"about_ca_system_score_codex":0.00006493518,"about_ca_system_score_gemma":0.00010440746,"threshold_uncertainty_score":0.8901438},"labels":[],"label_agreement":null},{"id":"W2769226978","doi":"10.3791/56301","title":"&lt;em&gt;In Vitro&lt;/em&gt; and &lt;em&gt;In Vivo&lt;/em&gt; Detection of Mitophagy in Human Cells,&lt;em&gt; C. Elegans&lt;/em&gt;, and Mice","year":2017,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"Medical Research Council; National Institutes of Health","keywords":"Mitophagy; Autophagy; Mitochondrion; Cell biology; Biology; Caenorhabditis elegans; In vivo; Genetics; Gene; Apoptosis","score_opus":0.01972023249050372,"score_gpt":0.3465654234689943,"score_spread":0.32684519097849063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2769226978","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9703352,0.023996681,0.00020832315,0.00017883423,0.0020056176,0.0019843709,0.0001155864,0.00012262519,0.0010528006],"genre_scores_gemma":[0.98966974,0.004401396,0.0011903658,0.000731268,0.0014419153,0.00016123152,0.000059222966,0.0003786718,0.001966202],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.98742896,0.0011244672,0.0043528145,0.0018595648,0.0030623951,0.0021718098],"domain_scores_gemma":[0.9916768,0.00040775476,0.0036501235,0.0019292557,0.00079715636,0.0015388762],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0028832476,0.0018880694,0.0038535178,0.00236284,0.0008665126,0.00065021554,0.0014751165,0.001269495,0.0009198616],"category_scores_gemma":[0.00053469825,0.0018162275,0.001007784,0.0009667204,0.0005835817,0.0018434593,0.0005393621,0.0016379926,0.000062770465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008631074,0.00401764,0.0014037576,0.00048198746,0.0009902751,0.0016742955,0.009273779,0.000021273354,0.9662974,0.00015177943,0.0017289936,0.0053277514],"study_design_scores_gemma":[0.040021043,0.0031568615,0.027539693,0.002100397,0.0006452695,0.0005285113,0.0024181749,0.0010157306,0.9096191,0.00057357777,0.010644442,0.00173721],"about_ca_topic_score_codex":0.00019675276,"about_ca_topic_score_gemma":0.0008054413,"teacher_disagreement_score":0.056678303,"about_ca_system_score_codex":0.0010561101,"about_ca_system_score_gemma":0.0005489568,"threshold_uncertainty_score":0.99999344},"labels":[],"label_agreement":null},{"id":"W2769529053","doi":"10.1097/cmr.0000000000000409","title":"In vitro and in vivo antimelanoma effect of ethyl ester cyclohexyl analog of ethylenediamine dipropanoic acid","year":2017,"lang":"en","type":"article","venue":"Melanoma Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Apoptosis; In vivo; Chemistry; Cancer research; Autophagy; Molecular biology; Flow cytometry; Biochemistry; Biology","score_opus":0.029829835195249677,"score_gpt":0.3837528294635898,"score_spread":0.3539229942683401,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2769529053","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99430025,0.0018258201,0.0000015049559,0.00058589515,0.000055599772,0.00060862233,0.000025635962,0.000006934596,0.0025897515],"genre_scores_gemma":[0.99875987,0.0002349778,0.00006161773,0.000027916458,0.00009742458,0.000046950616,0.000006859322,0.000025179865,0.00073922676],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997871,0.00039033918,0.00038320044,0.00034223674,0.0005635025,0.00044976044],"domain_scores_gemma":[0.99840367,0.00041485342,0.00012100131,0.0008088338,0.000103301834,0.00014834119],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018142693,0.00016823194,0.0006632386,0.00060998765,0.00007383297,0.000021562613,0.000310711,0.00018096529,0.00018155495],"category_scores_gemma":[0.00042445603,0.00013068844,0.00007919807,0.00024160846,0.0005456144,0.00016025057,0.00020321041,0.00046942758,0.000009906498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035185805,0.00018542093,0.31766653,0.0003893458,0.00004095777,0.0004738341,0.00016108951,2.0927571e-7,0.67392856,0.00002899414,0.00004219419,0.0035642728],"study_design_scores_gemma":[0.0035331403,0.00081351784,0.42006066,0.00015966696,0.00001075882,0.0000121653375,0.00001463548,0.0000650894,0.5750846,0.00012548358,0.00005861406,0.00006160653],"about_ca_topic_score_codex":0.00051736936,"about_ca_topic_score_gemma":0.00005173954,"teacher_disagreement_score":0.10239415,"about_ca_system_score_codex":0.00005015227,"about_ca_system_score_gemma":0.00010465311,"threshold_uncertainty_score":0.532932},"labels":[],"label_agreement":null},{"id":"W2769849361","doi":"10.1080/15548627.2017.1389824","title":"Autophagy and innate immunity: Insights from invertebrate model organisms","year":2017,"lang":"en","type":"review","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":163,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Institutes of Health; National Institute of General Medical Sciences; Ministry of Science and Technology, Taiwan; University of Waterloo","keywords":"Biology; Autophagy; Innate immune system; Immunity; Model organism; Invertebrate; Cell biology; Ecology; Immunology; Immune system; Genetics; Apoptosis; Gene","score_opus":0.09393622323520552,"score_gpt":0.3663194249310077,"score_spread":0.2723832016958022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2769849361","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0019275392,0.9921491,0.00009651346,0.00004395046,0.00055566884,0.0011858818,0.00020682022,0.0003530916,0.0034813944],"genre_scores_gemma":[0.0023912634,0.98903185,0.0004683027,0.0009350956,0.0004619906,0.00014730137,0.00088719354,0.000274834,0.0054021804],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99653655,0.0002428932,0.0010324356,0.001089289,0.00049489125,0.0006039107],"domain_scores_gemma":[0.995896,0.00016432225,0.0008249973,0.002405439,0.00011963919,0.00058962463],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017737059,0.0011192495,0.003747105,0.00040681256,0.0005193733,0.00021451783,0.00078328495,0.0010730097,0.00045842346],"category_scores_gemma":[0.00013150749,0.0008826774,0.00067687884,0.00023433687,0.00038544097,0.00033500927,0.00048832485,0.0012202472,0.0006704931],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045290875,0.0002581221,0.0000021276935,0.0044351756,0.0016919327,0.0010096219,0.0004385881,8.9987736e-7,0.00009411853,0.0021881151,0.00081071677,0.9890253],"study_design_scores_gemma":[0.00226307,0.0002085285,0.00012208887,0.009087444,0.0041100117,0.00019549375,0.000016292033,0.0031186405,0.0005550603,0.011164937,0.9679831,0.0011752835],"about_ca_topic_score_codex":0.00025137456,"about_ca_topic_score_gemma":0.000014270919,"teacher_disagreement_score":0.98785,"about_ca_system_score_codex":0.0001826076,"about_ca_system_score_gemma":0.0014840723,"threshold_uncertainty_score":0.9993624},"labels":[],"label_agreement":null},{"id":"W2770000599","doi":"10.1016/j.gde.2017.11.003","title":"Cross-talk between protein synthesis, energy metabolism and autophagy in cancer","year":2017,"lang":"en","type":"review","venue":"Current Opinion in Genetics & Development","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":136,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Health and Medical Research Council; Canadian Institutes of Health Research; Medical Research Council; Terry Fox Research Institute; Marshfield Clinic Research Foundation; Victorian Cancer Agency; National Cancer Institute; National Institutes of Health; Cancer Australia; U.S. Department of Health and Human Services","keywords":"Biology; Autophagy; Translation (biology); Cell biology; Function (biology); Signal transduction; Cancer; Regulation of gene expression; Protein biosynthesis; Energy homeostasis; Computational biology; Gene; Genetics; Messenger RNA; Apoptosis","score_opus":0.16274189080858428,"score_gpt":0.45298410952358575,"score_spread":0.29024221871500144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2770000599","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018119173,0.9948175,0.000029468876,0.0000215969,0.0018497298,0.0013088279,0.00007142076,0.00002969688,0.000059852093],"genre_scores_gemma":[0.00057318946,0.9952689,0.0004193777,0.000009376866,0.0007630665,0.0024260678,0.00026348227,0.00008681492,0.00018976294],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99678314,0.00015159804,0.0012571182,0.00080939103,0.00045353966,0.00054522755],"domain_scores_gemma":[0.9984206,0.000074691874,0.0005345186,0.0006201918,0.00007208714,0.00027794292],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037132288,0.0006603551,0.0020979089,0.00054078526,0.00011907454,0.00009199675,0.0004003401,0.00040747647,0.00012151417],"category_scores_gemma":[0.000061502884,0.00057215744,0.00019922193,0.00021583792,0.00014181659,0.00005495185,0.00025789742,0.00048614613,0.000014812764],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011962497,0.00015712631,0.0010101238,0.0117340665,0.00017978881,0.000009999962,0.00010387612,4.395626e-7,7.5260033e-7,0.00008725215,0.00004868486,0.98665595],"study_design_scores_gemma":[0.00073230616,0.000016657605,0.03216538,0.037653565,0.00016706341,0.0000069883463,0.0000023060575,0.0000035254752,0.0001738961,0.00010322497,0.928451,0.0005240974],"about_ca_topic_score_codex":0.000046363934,"about_ca_topic_score_gemma":0.0000105126055,"teacher_disagreement_score":0.98613185,"about_ca_system_score_codex":0.00035831935,"about_ca_system_score_gemma":0.0021538876,"threshold_uncertainty_score":0.999673},"labels":[],"label_agreement":null},{"id":"W2770240684","doi":"10.1155/2017/2376893","title":"Excessive Autophagy Activation and Increased Apoptosis Are Associated with Palmitic Acid-Induced Cardiomyocyte Insulin Resistance","year":2017,"lang":"en","type":"article","venue":"Journal of Diabetes Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; National Science Foundation","keywords":"Autophagy; Palmitic acid; Insulin resistance; Apoptosis; Cell biology; Lipotoxicity; Chemistry; Insulin; Endocrinology; Internal medicine; Biology; Biochemistry; Medicine; Fatty acid","score_opus":0.05048962806088148,"score_gpt":0.3518353416469171,"score_spread":0.3013457135860356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2770240684","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963755,0.0012301028,0.000005841907,0.0012892789,0.00005222003,0.00026214574,0.000010247041,0.000013072609,0.0007615859],"genre_scores_gemma":[0.9990593,0.00019964045,0.000076970326,0.000120435376,0.00027061155,0.000017715678,0.0000050518734,0.000029400706,0.00022087664],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9975937,0.00032941057,0.00032803867,0.00020809259,0.0011151282,0.00042563223],"domain_scores_gemma":[0.9967416,0.00042610883,0.000649861,0.0004433268,0.0013869567,0.0003521336],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013810563,0.00015513698,0.00053285743,0.00032865116,0.000543339,0.00018365926,0.0002748084,0.00014017629,0.0000329563],"category_scores_gemma":[0.003340704,0.00011252638,0.00010524608,0.00022504233,0.00024837535,0.000426142,0.00006661262,0.0007097011,0.0000034056238],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025079907,0.00069744355,0.30485475,0.00036950342,0.0024384344,0.0004165311,0.0005867302,0.0000017753041,0.6753099,0.00006900585,0.0011678186,0.011580149],"study_design_scores_gemma":[0.0030568403,0.0004985154,0.60601187,0.0010911245,0.00008274028,0.0000029258645,0.0001434695,0.000024348124,0.38862902,0.000291633,0.00008376681,0.00008375183],"about_ca_topic_score_codex":0.000013767005,"about_ca_topic_score_gemma":0.0000067152414,"teacher_disagreement_score":0.30115712,"about_ca_system_score_codex":0.0002257996,"about_ca_system_score_gemma":0.00042610927,"threshold_uncertainty_score":0.45886928},"labels":[],"label_agreement":null},{"id":"W2770295596","doi":"10.1080/15548627.2017.1403716","title":"In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy","year":2017,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"European Research Council; Associazione Italiana per la Ricerca sul Cancro; Deutsche Forschungsgemeinschaft","keywords":"Biology; Mitophagy; Cell biology; Skeletal muscle; Mitochondrion; PINK1; Phosphorylation; Mitochondrial biogenesis; Protein kinase A; Biochemistry; Autophagy; Endocrinology","score_opus":0.010269796501513204,"score_gpt":0.279693503252333,"score_spread":0.2694237067508198,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2770295596","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99156016,0.00220857,0.000067473775,0.0009961727,0.00025865412,0.0012191042,0.000056213015,0.00005841113,0.0035752554],"genre_scores_gemma":[0.9935377,0.000047120746,0.00024459066,0.00049694435,0.00019619327,0.00015867573,0.000049147864,0.000046718702,0.0052228803],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99815196,0.00007200153,0.00054168684,0.00041449838,0.00039502716,0.00042483417],"domain_scores_gemma":[0.99824876,0.000041211537,0.0003975632,0.0010062568,0.0001028701,0.0002033415],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00026989015,0.00027501836,0.0005812285,0.00012803733,0.00015954074,0.000044069573,0.00033537106,0.00020805863,0.0009926751],"category_scores_gemma":[0.00018744807,0.0002581371,0.0002030523,0.00010938414,0.00022321322,0.00034951695,0.000067027715,0.00025017656,0.00008727334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009776761,0.0019386553,0.0090011265,0.000359967,0.00023624323,0.0010971017,0.00051758904,0.00000569596,0.92090195,0.004435883,0.0065395916,0.053988494],"study_design_scores_gemma":[0.0082600955,0.0005335233,0.35005197,0.00018828071,0.00006692479,0.000014073676,0.000041620253,0.0002992408,0.62142074,0.0014970859,0.01731295,0.00031350597],"about_ca_topic_score_codex":0.00050234655,"about_ca_topic_score_gemma":0.00002703314,"teacher_disagreement_score":0.34105083,"about_ca_system_score_codex":0.00008725496,"about_ca_system_score_gemma":0.0001535744,"threshold_uncertainty_score":0.99998707},"labels":[],"label_agreement":null},{"id":"W2772187558","doi":"10.1016/j.tcm.2017.11.008","title":"Mitochondrial quality control: The role of mitophagy in aging","year":2017,"lang":"en","type":"review","venue":"Trends in Cardiovascular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital; University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Autophagy; Cell biology; Mitochondrion; Programmed cell death; Mechanism (biology); Organelle; Biology; Catabolism; Lysosome; Apoptosis; Metabolism; Biochemistry; Enzyme","score_opus":0.08564815086523872,"score_gpt":0.41749163556331015,"score_spread":0.33184348469807146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2772187558","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000052523552,0.99125254,0.000019337329,0.00015454492,0.00092331076,0.0008925954,0.000033786066,0.000030425857,0.0066409586],"genre_scores_gemma":[0.0054485234,0.9913922,0.000024771634,0.00007945108,0.0022821035,0.00021148041,0.00014698283,0.00008120322,0.00033326072],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9949268,0.0011080748,0.0016286935,0.0007030857,0.0011367591,0.0004965896],"domain_scores_gemma":[0.99559075,0.0004902844,0.0006302964,0.0030404343,0.000085084175,0.00016317028],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0026795573,0.00061376626,0.0070200027,0.0008800707,0.00006989419,0.000010552597,0.0006980149,0.00046387906,0.00019717007],"category_scores_gemma":[0.0005722515,0.0003592193,0.0033344717,0.00065111043,0.0005356901,0.00005680193,0.000082109014,0.0010293132,0.000011626192],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000095135394,0.00010229629,0.00019017723,0.0028576194,0.0033148848,0.00035875745,0.00023129037,0.0000037647537,0.00000311848,0.00010843201,0.00012134167,0.9926132],"study_design_scores_gemma":[0.008024817,0.00011782355,0.0034290277,0.018199552,0.005038319,0.00012329819,0.000094437564,0.0000074453437,0.000007451665,0.0001638462,0.9644964,0.00029762913],"about_ca_topic_score_codex":0.0010158229,"about_ca_topic_score_gemma":0.000060758553,"teacher_disagreement_score":0.99231553,"about_ca_system_score_codex":0.00019202776,"about_ca_system_score_gemma":0.00030104208,"threshold_uncertainty_score":0.999886},"labels":[],"label_agreement":null},{"id":"W2776100492","doi":"10.3390/v9120389","title":"Implication of Different HIV-1 Genes in the Modulation of Autophagy","year":2017,"lang":"en","type":"review","venue":"Viruses","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Autophagy; Crosstalk; Cell biology; Immune system; Biology; Human immunodeficiency virus (HIV); Virology; Immunology; Genetics; Apoptosis","score_opus":0.16910599737691973,"score_gpt":0.4343331370597046,"score_spread":0.2652271396827849,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2776100492","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010858521,0.9880951,0.000014434784,0.000014559,0.0000547151,0.00066526246,0.000062689716,0.000009355529,0.0002253544],"genre_scores_gemma":[0.030742282,0.9688563,0.00001252406,0.000034094002,0.00010599341,0.00008540598,0.00009955128,0.000017375238,0.000046505458],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990558,0.00008855539,0.00045055756,0.00014605281,0.0001752669,0.000083789586],"domain_scores_gemma":[0.9986006,0.000100172016,0.0005437019,0.00069974235,0.000034230932,0.000021532],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011580153,0.00015688318,0.000878363,0.00012835341,0.000024323015,0.000005797848,0.00022337247,0.0001255069,0.000044692333],"category_scores_gemma":[0.00003666507,0.00008606411,0.00024237738,0.000072936535,0.00006187989,0.000036402504,0.00002196446,0.00009324213,0.000011361414],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016242555,0.00020041969,0.0001967564,0.00554304,0.00010455489,0.0000027806786,0.00007096402,4.5642565e-7,0.00023739712,0.00052685046,0.00006284892,0.9930377],"study_design_scores_gemma":[0.000693008,0.00016022673,0.04723516,0.010219172,0.0012213557,0.000016918395,0.000016906168,0.00002355799,0.0028932414,0.0006026492,0.9367141,0.00020366811],"about_ca_topic_score_codex":0.00003019917,"about_ca_topic_score_gemma":0.000002161434,"teacher_disagreement_score":0.99283403,"about_ca_system_score_codex":0.000024120265,"about_ca_system_score_gemma":0.00009774791,"threshold_uncertainty_score":0.35095924},"labels":[],"label_agreement":null},{"id":"W2776614535","doi":"10.1073/pnas.1716055115","title":"<i>Listeria monocytogenes</i> triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy","year":2017,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Government of Canada; National Institutes of Health; National Science Foundation","keywords":"Autophagy; Vacuole; Listeria monocytogenes; Cell biology; Intracellular; Biology; Intracellular parasite; Cytoplasm; Cytosol; Phagosome; Phagocytosis; Microbiology; Bacteria; Biochemistry; Apoptosis; Genetics","score_opus":0.07937629548895013,"score_gpt":0.3581929352193068,"score_spread":0.27881663973035664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2776614535","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9870508,0.0007206829,0.0000015152826,0.003590818,0.00008690605,0.00034602266,0.000025758985,0.000029630488,0.008147894],"genre_scores_gemma":[0.9977504,0.0002493222,0.00065192336,0.00069062243,0.00030567223,0.000024773046,4.716158e-7,0.000012977077,0.00031385763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99717057,0.000012976765,0.00056659913,0.0004210764,0.0015103635,0.00031839916],"domain_scores_gemma":[0.99832064,0.000121583704,0.0009921547,0.000041080195,0.00038383852,0.00014067913],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012722667,0.00019912934,0.00039569146,0.00017774163,0.0007827998,0.00008631514,0.0013387447,0.00017024604,0.000043567004],"category_scores_gemma":[0.0009586019,0.00013714681,0.00024195002,0.00035256904,0.0011497282,0.00061385275,0.00024340762,0.0002709482,0.0000047093904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029706044,0.00021519103,0.013857492,0.00017903445,0.00011054873,4.3468532e-7,0.00016001177,0.000012286454,0.95985144,0.023734327,0.00044666632,0.0011354763],"study_design_scores_gemma":[0.0010989513,0.00014243263,0.12160496,0.00016588224,0.00007837894,0.000038950806,0.00008865094,0.00045033146,0.8673166,0.008672196,0.00021262372,0.00013001364],"about_ca_topic_score_codex":0.00004804084,"about_ca_topic_score_gemma":9.890534e-8,"teacher_disagreement_score":0.107747465,"about_ca_system_score_codex":0.000115143266,"about_ca_system_score_gemma":0.00023678852,"threshold_uncertainty_score":0.6020742},"labels":[],"label_agreement":null},{"id":"W2778144869","doi":"10.1016/j.neuropharm.2017.12.029","title":"Adenosine monophosphate-activated protein kinase modulation by berberine attenuates mitochondrial deficits and redox imbalance in experimental diabetic neuropathy","year":2017,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"AMPK; Mitochondrial biogenesis; Pharmacology; Protein kinase A; TFAM; AMP-activated protein kinase; Streptozotocin; Adenosine; Endocrinology; Adenosine monophosphate; Medicine; Internal medicine; Chemistry; Mitochondrion; Diabetes mellitus; Kinase; Biochemistry","score_opus":0.011553503088953544,"score_gpt":0.290400142007133,"score_spread":0.27884663891817946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2778144869","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99538994,0.0017584817,0.000003811953,0.0010719122,0.00053696765,0.001056532,0.000017747101,0.000070116694,0.00009446576],"genre_scores_gemma":[0.99825513,0.00019062833,0.00006073628,0.0007640505,0.0001971792,0.00018931115,0.00002625304,0.000053740037,0.00026293847],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985425,0.0001259011,0.00029739217,0.000515414,0.00015696565,0.00036181358],"domain_scores_gemma":[0.99918133,0.000044141758,0.0001917502,0.00034937906,0.00004484666,0.00018855545],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000466667,0.00025487613,0.00037570897,0.00008340798,0.00018972706,0.000041967596,0.0001612101,0.00010196591,0.0001430155],"category_scores_gemma":[0.0000978349,0.00025060747,0.00004707831,0.00008210892,0.00020170187,0.00018625376,0.00010664481,0.00027974564,0.000020914798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020562634,0.00052216294,0.007936643,0.000033674096,0.000025158908,0.0007414832,0.00007484377,0.000013345777,0.987131,0.0000116068095,0.00034198738,0.0011118099],"study_design_scores_gemma":[0.0069114934,0.00072185526,0.1609482,0.000033308916,0.000035540863,0.000025957415,0.000005619396,0.0015908849,0.82891333,0.000021226215,0.00062065554,0.00017194294],"about_ca_topic_score_codex":0.000057753285,"about_ca_topic_score_gemma":8.636142e-7,"teacher_disagreement_score":0.1582177,"about_ca_system_score_codex":0.000046477984,"about_ca_system_score_gemma":0.00003630552,"threshold_uncertainty_score":0.99999464},"labels":[],"label_agreement":null},{"id":"W2781438577","doi":"10.1074/jbc.m117.808675","title":"Countervailing, time-dependent effects on host autophagy promote intracellular survival of Leishmania","year":2017,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; PI3K/AKT/mTOR pathway; Cell biology; ATG5; Leishmania; Biology; Protein kinase B; Intracellular parasite; Context (archaeology); Intracellular; Leishmania major; Signal transduction; Apoptosis; Biochemistry; Parasite hosting","score_opus":0.018200809033457273,"score_gpt":0.28108620342337304,"score_spread":0.26288539438991576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2781438577","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967133,0.00087371806,0.000028167893,0.0002490548,0.00018461182,0.00011438379,0.000009283779,0.000014935271,0.0018125775],"genre_scores_gemma":[0.9981724,0.00018450529,0.00009079102,0.00009853663,0.0006658236,0.0000016253151,0.0000053722124,0.000012336825,0.000768601],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987967,0.000039948423,0.00044919708,0.00017327603,0.00034592827,0.00019497304],"domain_scores_gemma":[0.99837124,0.000101988575,0.0007580337,0.0003988333,0.00016863142,0.00020129637],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000467778,0.00017574904,0.0005791951,0.000020382924,0.00008541941,0.000026222584,0.00035718648,0.00023968023,0.0005368145],"category_scores_gemma":[0.00050467683,0.00011180607,0.00028418432,0.000022010823,0.00016342645,0.00004927001,0.00005941119,0.0004104788,0.000025840864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009182233,0.00049366994,0.004045659,0.00017645741,0.00021022912,0.0009387195,0.000019250756,0.0000011217918,0.9908964,0.000006445118,0.00013564737,0.0021581945],"study_design_scores_gemma":[0.0020310096,0.001186135,0.036177974,0.00035794784,0.00008284871,0.00016449057,0.000010125487,0.000036487567,0.9589843,0.00013347004,0.00072865945,0.00010654872],"about_ca_topic_score_codex":0.0000017685354,"about_ca_topic_score_gemma":4.3916412e-8,"teacher_disagreement_score":0.032132316,"about_ca_system_score_codex":0.00005385911,"about_ca_system_score_gemma":0.00008626597,"threshold_uncertainty_score":0.5877743},"labels":[],"label_agreement":null},{"id":"W2781528910","doi":"10.1042/bst20170102","title":"Evolution of tools and methods for monitoring autophagic flux in mammalian cells","year":2018,"lang":"en","type":"review","venue":"Biochemical Society Transactions","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Simon Fraser University; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Flux (metallurgy); Cell biology; Computational biology; Biology; Chemistry; Computer science; Biological system; Biochemistry","score_opus":0.05516686087926513,"score_gpt":0.39918460556180346,"score_spread":0.3440177446825383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2781528910","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00033570037,0.95071894,0.047490306,0.00001871322,0.00023778265,0.00096578937,0.00017259744,0.000037017857,0.000023149141],"genre_scores_gemma":[0.00039293413,0.9454714,0.05314813,0.000011915314,0.0002896424,0.00027093512,0.00007346266,0.000042603955,0.00029898385],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99874955,0.000058510483,0.0004927259,0.00035502456,0.00010646487,0.00023771854],"domain_scores_gemma":[0.99917835,0.00025814492,0.00013212064,0.00023537032,0.00006100933,0.0001349763],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025589034,0.00025604593,0.00096591405,0.000055959084,0.00006181861,0.0000106581865,0.000088305016,0.00056315534,0.000066837325],"category_scores_gemma":[0.000018512945,0.00022458767,0.0010249033,0.00026390367,0.00016569618,0.000048663063,0.0000061244004,0.00028515936,0.0000030265335],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004841693,0.0004189846,0.0000041716507,0.027738474,0.00065625453,0.0000011330675,0.00023939057,3.598263e-7,0.020947227,0.000027181357,0.0005568216,0.94936156],"study_design_scores_gemma":[0.002001881,0.00029228392,0.000101381906,0.011214832,0.0045205145,0.000031081592,0.00020727045,0.00016340197,0.112143785,0.00029490743,0.8684124,0.0006163101],"about_ca_topic_score_codex":0.00001138829,"about_ca_topic_score_gemma":1.14852526e-7,"teacher_disagreement_score":0.94874525,"about_ca_system_score_codex":0.00026878962,"about_ca_system_score_gemma":0.00023291924,"threshold_uncertainty_score":0.9158419},"labels":[],"label_agreement":null},{"id":"W2781668238","doi":"10.1161/circresaha.117.311240","title":"Autophagy Is Required for Sortilin-Mediated Degradation of Apolipoprotein B100","year":2018,"lang":"en","type":"article","venue":"Circulation Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; National Institutes of Health; School of Medicine, New York University; York University; American Heart Association; American Diabetes Association","keywords":"Apolipoprotein B; Very low-density lipoprotein; Autophagy; Biology; Lipoprotein; Apolipoprotein E; Cell biology; Secretion; Endosome; Cholesterol; Chemistry; Molecular biology; Genetics; Biochemistry; Intracellular; Internal medicine; Medicine; Apoptosis","score_opus":0.137188175179614,"score_gpt":0.43906435863558346,"score_spread":0.30187618345596945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2781668238","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99270946,0.00024337594,0.0032923908,0.00082682987,0.00008259643,0.0013222218,0.00003114608,0.00005615032,0.0014358268],"genre_scores_gemma":[0.9970992,0.00002053282,0.000451673,0.0001972095,0.0003426896,0.00012639219,0.00018275238,0.000025964942,0.0015535479],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832016,0.00011708834,0.00033925168,0.0002706708,0.00064077356,0.00031205747],"domain_scores_gemma":[0.99795455,0.00021681926,0.0000922223,0.00041187688,0.0011819346,0.00014259161],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009838523,0.000090008485,0.00020055265,0.00031056296,0.00019021006,0.000016257361,0.00010313308,0.00013379302,0.0008545982],"category_scores_gemma":[0.0007013225,0.0000841673,0.00009977578,0.0005399102,0.00026940336,0.000112425914,0.000022287732,0.00014288902,0.00013856075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024002485,0.0007484041,0.01877744,0.00061134197,0.00034054279,0.000011224304,0.0018247291,0.000017174934,0.9002025,0.005737555,0.008358473,0.06097036],"study_design_scores_gemma":[0.004777529,0.0010174516,0.30026785,0.00016194701,0.000060109818,0.0000069328767,0.0002506517,0.04507907,0.63371754,0.009939037,0.0045242845,0.00019761102],"about_ca_topic_score_codex":0.000095697884,"about_ca_topic_score_gemma":0.000006439932,"teacher_disagreement_score":0.2814904,"about_ca_system_score_codex":0.000085191175,"about_ca_system_score_gemma":0.00032208278,"threshold_uncertainty_score":0.93572503},"labels":[],"label_agreement":null},{"id":"W2782694520","doi":"10.1242/jcs.209098","title":"Septins are involved at the early stages of macroautophagy in <i>S. cerevisiae</i>","year":2018,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"The Wellcome Trust DBT India Alliance; Jawaharlal Nehru Centre for Advanced Scientific Research; Council of Scientific and Industrial Research, India; University of Alberta; Wellcome Trust","keywords":"Biology; Septin; Cell biology; Autophagy; Saccharomyces cerevisiae; Genetics; Gene; Cell; Cytokinesis; Cell division; Apoptosis","score_opus":0.01488402523460075,"score_gpt":0.2883237094833054,"score_spread":0.27343968424870463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2782694520","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941551,0.0014350547,0.000015255119,0.00048456914,0.00016702987,0.000097582444,0.0000022393076,0.0000035461044,0.003639638],"genre_scores_gemma":[0.99773,0.00022926423,0.0001871387,0.00057947147,0.00016483167,5.819634e-7,1.0313263e-7,0.000006273905,0.001102315],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986417,0.000038220376,0.0003736587,0.00011872104,0.00061524316,0.00021244056],"domain_scores_gemma":[0.9987745,0.000056092522,0.000471951,0.00024590292,0.0003099061,0.00014159134],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009042107,0.00008185197,0.00023416292,0.00013463265,0.000097911885,0.00001971114,0.000367918,0.00003129399,0.00037074054],"category_scores_gemma":[0.000075232165,0.000046210716,0.0000989801,0.00055113697,0.00084246596,0.00018649836,0.00006683478,0.00016038983,0.000022930451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003294676,0.0002987274,0.18639392,0.00005747657,0.000020278057,0.00015450043,0.0020178226,0.000007680114,0.806883,0.00007410037,0.0016646448,0.0020984162],"study_design_scores_gemma":[0.00096245814,0.0005278326,0.36347306,0.00015573499,0.00002457791,0.000035139612,0.00026499666,0.000025262534,0.63154876,0.00015624329,0.002771867,0.000054059743],"about_ca_topic_score_codex":0.000012808553,"about_ca_topic_score_gemma":0.000015550211,"teacher_disagreement_score":0.17707914,"about_ca_system_score_codex":0.00008210533,"about_ca_system_score_gemma":0.00030119397,"threshold_uncertainty_score":0.4059349},"labels":[],"label_agreement":null},{"id":"W2783183838","doi":"10.1038/cddiscovery.2017.68","title":"Involvement of proapoptotic genes in autophagic cell death induced by irradiation","year":2017,"lang":"en","type":"article","venue":"Cell Death Discovery","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"School of Medicine, New York University; Science and Technology Commission of Shanghai Municipality; National Natural Science Foundation of China; Priority Academic Program Development of Jiangsu Higher Education Institutions; York University; American Heart Association","keywords":"Autophagy; Programmed cell death; Apoptosis; Cell biology; Gene; Cell; Cancer research; Biology; Chemistry; Genetics","score_opus":0.030275651397634964,"score_gpt":0.2838802224688028,"score_spread":0.25360457107116785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2783183838","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902443,0.0027185986,0.000059509977,0.00008641058,0.00022100042,0.000625552,0.000025003023,0.000025128691,0.005994455],"genre_scores_gemma":[0.9960706,0.0006102937,0.00012549352,0.00025160966,0.00009996971,0.000053078737,0.000095839336,0.00003306213,0.002660005],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986544,0.000040130206,0.00036775213,0.00034123886,0.00029784744,0.00029861578],"domain_scores_gemma":[0.998756,0.000028309862,0.0002963923,0.0007515232,0.000040375162,0.00012743322],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001573055,0.00021629436,0.00036930828,0.00011353481,0.00011263307,0.00006726877,0.00024028486,0.00012685398,0.00007028826],"category_scores_gemma":[0.000022055183,0.00018970732,0.00012953048,0.00006219522,0.000046760095,0.0003964477,0.00006778559,0.00015227887,0.000030890613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041099597,0.0026340534,0.32381758,0.00086655695,0.000104392726,0.000103324324,0.0007794657,0.000044524142,0.6669613,0.0007211661,0.00048656444,0.003070063],"study_design_scores_gemma":[0.0031412742,0.00030888626,0.49662802,0.000121504345,0.000103942264,0.0000012707362,0.00009082685,0.00040857602,0.49817136,0.00056231726,0.00025723068,0.00020478542],"about_ca_topic_score_codex":0.00027604378,"about_ca_topic_score_gemma":0.000007599392,"teacher_disagreement_score":0.17281045,"about_ca_system_score_codex":0.000121142584,"about_ca_system_score_gemma":0.00022569092,"threshold_uncertainty_score":0.77360404},"labels":[],"label_agreement":null},{"id":"W2783209833","doi":"10.1074/jbc.ra117.000809","title":"ER-stress mobilization of death-associated protein kinase-1–dependent xenophagy counteracts mitochondria stress–induced epithelial barrier dysfunction","year":2018,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Calgary","funders":"Canadian Institutes of Health Research; Institute of Nutrition, Metabolism and Diabetes; Alberta Innovates; Cumming School of Medicine, University of Calgary; Allergan; Canadian Association of Gastroenterology; Alberta Innovates - Health Solutions","keywords":"Unfolded protein response; Cell biology; Barrier function; Autophagy; Endoplasmic reticulum; Biology; Tunicamycin; ATF6; Mitochondrion; Apoptosis; Biochemistry","score_opus":0.02196418041960889,"score_gpt":0.28085505030031416,"score_spread":0.25889086988070525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2783209833","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99837154,0.00032618985,0.00011314232,0.000067334426,0.00029538004,0.00024374206,0.000101235055,0.000023393055,0.00045806047],"genre_scores_gemma":[0.9982462,0.00006576326,0.00009361463,0.000097709715,0.0010875298,0.000009729835,0.000066686924,0.000015889385,0.00031687182],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983274,0.00008205612,0.0006934251,0.00022202307,0.0004362686,0.00023886358],"domain_scores_gemma":[0.997944,0.00006749751,0.0007905976,0.00021264204,0.00074856105,0.00023672535],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00024552428,0.0002069675,0.00048087025,0.00004535184,0.00006908355,0.000017393064,0.00016934365,0.0003814517,0.0011319116],"category_scores_gemma":[0.00066264387,0.00014140528,0.00022179069,0.00013426447,0.00012197931,0.000091711976,0.00003387345,0.00034534067,0.000008138124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016929993,0.0008259797,0.007834968,0.000074752694,0.00021772814,0.000098076496,0.00006122881,0.000004929319,0.9885723,0.000005026528,0.00006450129,0.0005475019],"study_design_scores_gemma":[0.0025426454,0.0014138396,0.02001564,0.00044767073,0.00011344326,0.000053808337,0.00012081334,0.000052476997,0.97479177,0.00018131519,0.00013585718,0.00013073078],"about_ca_topic_score_codex":0.000008894048,"about_ca_topic_score_gemma":0.0000011404981,"teacher_disagreement_score":0.013780548,"about_ca_system_score_codex":0.0001532465,"about_ca_system_score_gemma":0.0001862676,"threshold_uncertainty_score":0.9997812},"labels":[],"label_agreement":null},{"id":"W2783965340","doi":"10.1074/jbc.m117.817635","title":"TRPM2 channel–mediated regulation of autophagy maintains mitochondrial function and promotes gastric cancer cell survival via the JNK-signaling pathway","year":2018,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; Izaak Walton Killam Health Centre","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Autophagy; TRPM2; Cell biology; Cancer; Cancer research; Function (biology); Mitochondrion; Signal transduction; Cell function; Cell survival; Apoptosis; Cell; Biology; Chemistry; Medicine; Internal medicine; Transient receptor potential channel; Receptor; Biochemistry","score_opus":0.020360401930945293,"score_gpt":0.25387896994653947,"score_spread":0.23351856801559417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2783965340","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99626845,0.001756483,0.0012162905,0.00018483755,0.00026900682,0.00012385088,0.000011888832,0.000013100742,0.00015610064],"genre_scores_gemma":[0.9976295,0.00016967338,0.00009840831,0.00008965015,0.0019089296,0.0000041364046,0.000013654144,0.000008285372,0.0000777146],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990164,0.00006120393,0.00040608825,0.00013904148,0.00021445015,0.00016280549],"domain_scores_gemma":[0.9989508,0.00011994527,0.00044762614,0.00010913326,0.00025031276,0.000122217],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002672895,0.00012940628,0.0002957508,0.000020445,0.00007066895,0.000009117641,0.00008688585,0.00018190748,0.0005501786],"category_scores_gemma":[0.00011833958,0.000070423834,0.0001260226,0.00012349762,0.0002058205,0.0000470674,0.000022982746,0.00020681662,0.0000012292586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012658045,0.00016190816,0.0010533049,0.000044233904,0.00008729118,0.000009389672,0.00008564063,0.0000048194665,0.9960506,0.0000034473555,0.000045438523,0.0011881324],"study_design_scores_gemma":[0.0018975188,0.0010681021,0.029868165,0.00008807755,0.00010740142,0.00007268238,0.00014323484,0.00031858645,0.9653434,0.0008122575,0.00019446714,0.00008606246],"about_ca_topic_score_codex":0.000007984155,"about_ca_topic_score_gemma":6.898892e-7,"teacher_disagreement_score":0.030707145,"about_ca_system_score_codex":0.00005445126,"about_ca_system_score_gemma":0.00010531682,"threshold_uncertainty_score":0.6024069},"labels":[],"label_agreement":null},{"id":"W2788488195","doi":"10.1128/mcb.00023-18","title":"AMPK Inhibits ULK1-Dependent Autophagosome Formation and Lysosomal Acidification via Distinct Mechanisms","year":2018,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":111,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Kingston Health Sciences Centre; Kingston General Hospital; Queen's University","funders":"Cancer Research UK; National Institutes of Health; Biotechnology and Biological Sciences Research Council; National Institute of Neurological Disorders and Stroke; Tertiary Education Trust Fund; Research Councils UK","keywords":"Autophagy; mTORC1; ULK1; AMPK; Cell biology; Biology; Autophagosome; Lysosome; AMP-activated protein kinase; Phosphorylation; BAG3; Protein kinase A; Biochemistry; Sequestosome 1; Protein kinase B","score_opus":0.008073774212452723,"score_gpt":0.24413253532316975,"score_spread":0.23605876111071702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2788488195","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8216458,0.0013393316,0.17607841,0.0002099371,0.00008807162,0.00024031384,0.000007316534,0.000048619037,0.0003422267],"genre_scores_gemma":[0.9985161,0.000055806562,0.0004779638,0.00053654116,0.00009522297,0.000021301805,0.00019016379,0.000016302978,0.00009060808],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991385,0.00007258206,0.0001986486,0.00029011891,0.000092843184,0.00020732004],"domain_scores_gemma":[0.99951017,0.000010193467,0.000072560746,0.00021286543,0.000061330014,0.00013287972],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012627734,0.00015112192,0.00019853693,0.000077182616,0.000116897085,0.000016116237,0.000047087116,0.00015926045,0.0000697732],"category_scores_gemma":[0.00001605127,0.00012754231,0.000048081136,0.000071749186,0.00015739242,0.000054453856,0.00004823135,0.00008524038,0.00003674258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009458245,0.000055060395,0.00022599778,0.000030148754,0.000044377834,0.00003612375,0.00013935241,6.242258e-8,0.9811834,0.0071593677,0.0000058068445,0.011025735],"study_design_scores_gemma":[0.0010948962,0.0005911338,0.0024099273,0.000015055585,0.00008501352,0.00013975336,0.00003337688,0.00055210816,0.98068285,0.013752412,0.000504124,0.0001393429],"about_ca_topic_score_codex":0.000011460451,"about_ca_topic_score_gemma":0.000002261139,"teacher_disagreement_score":0.1768703,"about_ca_system_score_codex":0.0000181366,"about_ca_system_score_gemma":0.000019773579,"threshold_uncertainty_score":0.5201025},"labels":[],"label_agreement":null},{"id":"W2788693662","doi":"10.1016/j.celrep.2018.02.024","title":"Aspirin Recapitulates Features of Caloric Restriction","year":2018,"lang":"en","type":"article","venue":"Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":107,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Cancer Research; European Research Council; National Institutes of Health; Chancellerie des Universités de Paris; Cancéropôle Ile de France; Institut Universitaire de France; Ligue Contre le Cancer; Ministerio de Economía y Competitividad; Bundesministerium für Wissenschaft, Forschung und Wirtschaft; Fondation pour la Recherche Médicale; Institut National Du Cancer; University of Minnesota; Institut National de la Santé et de la Recherche Médicale; Austrian Science Fund; Agence Nationale de la Recherche; Fondation Leducq; European Commission; Association pour la Recherche sur le Cancer; Fundación BBVA","keywords":"Autophagy; Caenorhabditis elegans; Biology; Cell biology; Flux (metallurgy); Metabolite; Aspirin; Acetylation; Endogeny; Biochemistry; Chemistry; Apoptosis; Gene","score_opus":0.01123849108887974,"score_gpt":0.26872161452650367,"score_spread":0.2574831234376239,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2788693662","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9507368,0.0011866696,0.000028055128,0.00005075857,0.00047251934,0.000139913,6.4568786e-7,0.000049638173,0.047334973],"genre_scores_gemma":[0.9945967,0.00015830094,0.00016645278,0.00011636204,0.0003580987,0.0000045972756,0.000017040378,0.000012600476,0.0045698225],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99931,0.000011700684,0.000231426,0.00016853597,0.00016558326,0.000112761314],"domain_scores_gemma":[0.9992904,0.0000143443485,0.00015920438,0.00034352305,0.000110744215,0.000081785525],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009224574,0.000075382275,0.00015102499,0.00006975233,0.000035921294,0.0000037715029,0.000023310997,0.00007205125,0.0002173252],"category_scores_gemma":[0.000039524646,0.000060638155,0.000071112496,0.00015201274,0.00006657565,0.000030864772,0.000011771776,0.00006913998,0.000019586998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009475848,0.0015324728,0.16903141,0.00058562786,0.0003156086,0.0068113534,0.0013531272,0.000008018544,0.6855456,0.00059880037,0.09365838,0.03961201],"study_design_scores_gemma":[0.00030692486,0.00038234593,0.27611813,0.000056699617,0.00007818537,0.00023121102,0.00002965745,0.0000051051143,0.703511,0.0015142376,0.017688489,0.00007803306],"about_ca_topic_score_codex":0.000071419614,"about_ca_topic_score_gemma":0.0000019051074,"teacher_disagreement_score":0.10708672,"about_ca_system_score_codex":0.00002059152,"about_ca_system_score_gemma":0.00007647143,"threshold_uncertainty_score":0.24727522},"labels":[],"label_agreement":null},{"id":"W2790388852","doi":"10.1007/s40291-018-0329-9","title":"Programmed Cell Death, from a Cancer Perspective: An Overview","year":2018,"lang":"en","type":"review","venue":"Molecular Diagnosis & Therapy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":186,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Winnipeg","funders":"","keywords":"Programmed cell death; Cancer; Cancer therapy; Autophagy; Cause of death; Medicine; Cancer cell; Apoptosis; Bioinformatics; Cancer research; Biology; Disease; Pathology; Internal medicine; Genetics","score_opus":0.11220002801105934,"score_gpt":0.43231557187329006,"score_spread":0.32011554386223073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790388852","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002682779,0.99121916,0.000020569201,0.0001929575,0.00033477583,0.004762034,0.00022567583,0.00025005656,0.0003119975],"genre_scores_gemma":[0.00011230772,0.9860086,0.0004519929,0.0028333014,0.001115037,0.0084313005,0.0005607928,0.00036114044,0.00012552743],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99612194,0.0005289097,0.00065958546,0.0013660194,0.00063595286,0.00068756274],"domain_scores_gemma":[0.9969657,0.00012437011,0.0004293104,0.0016326868,0.0002883253,0.00055962015],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018633936,0.0010499302,0.0025834725,0.00023090772,0.00013104282,0.000116143434,0.000599771,0.0006515477,0.0031939591],"category_scores_gemma":[0.00002426385,0.0008060091,0.0016947123,0.0005408959,0.00014953259,0.00010189595,0.0000677082,0.00054890115,0.0002635451],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001011375,0.00213441,0.00012883107,0.0019185027,0.0022884228,0.0005129325,0.00036533872,8.811426e-8,0.000027814001,0.00018094716,0.0010945078,0.99124706],"study_design_scores_gemma":[0.001956066,0.0008183722,0.00021111536,0.008906747,0.002859506,0.00001312419,0.000033750213,0.000002028433,0.0009560234,0.0006527552,0.98277515,0.0008153878],"about_ca_topic_score_codex":0.0013340794,"about_ca_topic_score_gemma":0.000027847123,"teacher_disagreement_score":0.99043167,"about_ca_system_score_codex":0.00048764562,"about_ca_system_score_gemma":0.0008979296,"threshold_uncertainty_score":0.99943906},"labels":[],"label_agreement":null},{"id":"W2790507218","doi":"10.1101/279885","title":"<i>Drosophila</i> egg-derived tyrosine phosphatase (EDTP): a novel target for improved survivorship to prolonged anoxia and cellular protein aggregates","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Fundamental Research Funds for the Central Universities; Nanjing University; Nanjing University of Science and Technology; National Natural Science Foundation of China","keywords":"Biology; Downregulation and upregulation; Phosphatase; Protein tyrosine phosphatase; Hippocampal formation; Cell biology; Hippocampus; Autophagy; Endocrinology; Internal medicine; Molecular biology; Gene; Genetics; Phosphorylation; Medicine","score_opus":0.014921601747818881,"score_gpt":0.23254311105042375,"score_spread":0.21762150930260488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790507218","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9713072,0.010906913,0.003575893,0.001522868,0.0007532608,0.008744515,0.0026255746,0.00056138035,0.0000023925022],"genre_scores_gemma":[0.96629715,0.00015147889,0.027399253,0.0015488007,0.0013508478,0.0028506694,0.00001895429,0.00035608947,0.000026743364],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99580467,0.000098434226,0.00081636815,0.0018399653,0.00041302247,0.001027564],"domain_scores_gemma":[0.995524,0.000079185455,0.00058294076,0.0018192884,0.00097008946,0.001024497],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00086287654,0.0010605572,0.0013137815,0.0003090821,0.00028734028,0.00022959911,0.0005151854,0.0008102299,0.00006309444],"category_scores_gemma":[0.00055443274,0.0010451238,0.00029749557,0.0004903275,0.00030584077,0.00015821945,0.0004823738,0.0006633103,0.00003688186],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018208739,0.0006581256,0.00093230733,0.0016044461,0.00048106717,0.00006382383,0.000023234032,0.0000020326029,0.993926,0.00020281048,0.0002798131,0.000005478626],"study_design_scores_gemma":[0.0041988282,0.00091966096,0.009912957,0.0010839725,0.0004276373,7.9478454e-8,0.0000022032534,0.00053529534,0.9756968,0.000029753703,0.0060915407,0.0011012406],"about_ca_topic_score_codex":0.00007489629,"about_ca_topic_score_gemma":0.0000035949104,"teacher_disagreement_score":0.02382336,"about_ca_system_score_codex":0.0001965518,"about_ca_system_score_gemma":0.00085570064,"threshold_uncertainty_score":0.9991999},"labels":[],"label_agreement":null},{"id":"W2790580707","doi":"10.1111/cmi.12824","title":"Lysosome remodelling and adaptation during phagocyte activation","year":2018,"lang":"en","type":"review","venue":"Cellular Microbiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Research, Innovation and Science; Canada Research Chairs; Ryerson University","keywords":"TFEB; Lysosome; Autophagy; Cell biology; Biology; Phagocytosis; Antigen presentation; Phagocyte; Endocytosis; Cellular adaptation; Macrophage; Immune system; Immunology; Cell; T cell; Biochemistry; Gene","score_opus":0.05393045998787303,"score_gpt":0.3008934672786037,"score_spread":0.24696300729073067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790580707","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009488692,0.9884734,0.0010193891,0.000011261506,0.00019705271,0.0006091155,0.000018263807,0.000064225016,0.00011856323],"genre_scores_gemma":[0.0007321798,0.99588966,0.0005644365,0.00006656396,0.0005496659,0.000025223693,0.0011209609,0.000061540006,0.0009897545],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99866134,0.00011999797,0.000449832,0.00047826272,0.00003731541,0.00025327568],"domain_scores_gemma":[0.99919444,0.000050092018,0.00029710814,0.00031603378,0.000057611396,0.00008469288],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012668667,0.00031611082,0.0010032944,0.00019928756,0.00010072539,0.000012054857,0.0000836548,0.0004915792,0.00010433528],"category_scores_gemma":[0.00001949875,0.00026138828,0.0002337749,0.00012497939,0.00013990329,0.000046620444,0.000044873013,0.00026067527,0.00013880184],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029862844,0.00022791834,0.000004784799,0.037477415,0.0017122744,0.0002144888,0.0005379431,0.000002986291,0.19735697,0.0002151936,0.00025330653,0.76169807],"study_design_scores_gemma":[0.00077960663,0.0001216848,0.0000016502903,0.0058577955,0.0010066931,0.00044580208,0.000015915382,0.00007663931,0.011170279,0.00007171708,0.9801154,0.00033681034],"about_ca_topic_score_codex":0.0000027246026,"about_ca_topic_score_gemma":2.2644633e-7,"teacher_disagreement_score":0.9798621,"about_ca_system_score_codex":0.00010097192,"about_ca_system_score_gemma":0.00014800184,"threshold_uncertainty_score":0.99998385},"labels":[],"label_agreement":null},{"id":"W2790614817","doi":"10.1016/j.bbamcr.2018.02.007","title":"Autophagy modulates transforming growth factor beta 1 induced epithelial to mesenchymal transition in non-small cell lung cancer cells","year":2018,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"","keywords":"Autophagy; Vimentin; Epithelial–mesenchymal transition; Cancer research; Gene knockdown; Mesenchymal stem cell; Cancer cell; Transforming growth factor; Lung cancer; Bafilomycin; Biology; Cancer; Cell biology; Chemistry; Cell culture; Medicine; Metastasis; Pathology; Immunology; Internal medicine; Apoptosis; Immunohistochemistry; Biochemistry","score_opus":0.026075547764607458,"score_gpt":0.33333499118425636,"score_spread":0.3072594434196489,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790614817","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929467,0.00019008562,0.00047894914,0.0019882368,0.00020638274,0.0024096589,0.0001728112,0.00009221414,0.0015149871],"genre_scores_gemma":[0.9970947,0.00029906342,0.00049212144,0.00088196236,0.0004773851,0.0002554839,0.00008507577,0.00016070972,0.00025352353],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9951686,0.00042298678,0.00060671533,0.0011693421,0.0012234764,0.0014088546],"domain_scores_gemma":[0.99777395,0.0001315965,0.00010178526,0.00078408816,0.00048495378,0.00072364765],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000553838,0.00057237124,0.000696026,0.0008626699,0.00025458843,0.00011890467,0.0006138642,0.00041092167,0.00022922522],"category_scores_gemma":[0.000021079171,0.00053775957,0.00038985268,0.0014573721,0.00025739105,0.00019733659,0.00013161032,0.0010393426,0.0001362338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00088968186,0.0009135938,0.000009488016,0.00036793432,0.00012358709,0.00018290147,0.0050975992,0.000009197633,0.991463,0.00003768467,0.00012267768,0.0007826254],"study_design_scores_gemma":[0.0027678867,0.0012563303,0.0033172956,0.0002772444,0.00010690994,0.0000025785762,0.00017025882,0.0019475401,0.9894566,0.000097926444,0.0000604938,0.00053891866],"about_ca_topic_score_codex":0.0008944697,"about_ca_topic_score_gemma":0.000034721186,"teacher_disagreement_score":0.0049273404,"about_ca_system_score_codex":0.00030766785,"about_ca_system_score_gemma":0.00076842343,"threshold_uncertainty_score":0.9997074},"labels":[],"label_agreement":null},{"id":"W2790748274","doi":"10.1002/art.40470","title":"Lupus Regulator Peptide P140 Represses B Cell Differentiation by Reducing HLA Class II Molecule Overexpression","year":2018,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Centre National de la Recherche Scientifique; Canadian Arthritis Network; Agence Nationale de la Recherche","keywords":"Flow cytometry; Cell biology; B-cell receptor; Systemic lupus erythematosus; Biology; Molecular biology; Endocytosis; Chemistry; B cell; Receptor; Immunology; Antibody; Biochemistry; Medicine","score_opus":0.005408970934274071,"score_gpt":0.23890923769939063,"score_spread":0.23350026676511657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2790748274","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98854506,0.0054690316,0.00030276933,0.0004991464,0.00064074364,0.00031315786,0.000022695573,0.00019616433,0.004011258],"genre_scores_gemma":[0.9945116,0.0019499857,0.00030935506,0.00044414663,0.00009762619,0.00004699474,0.00016029383,0.000051935236,0.0024280702],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99812067,0.000118171,0.0004734152,0.00057645096,0.00025702894,0.0004542487],"domain_scores_gemma":[0.9986886,0.00007272477,0.00022567461,0.0006602986,0.00013602423,0.00021667035],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009434884,0.00024925874,0.0005149292,0.00010285431,0.0003601457,0.000025161651,0.00013986975,0.00023957765,0.0011733806],"category_scores_gemma":[0.000101811034,0.00023826398,0.00012814601,0.00013530586,0.00026319164,0.0001586583,0.00011991829,0.00019055109,0.00016273811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00067263166,0.0008287198,0.023160176,0.00014843476,0.00015835394,0.0000873656,0.001514343,0.0000021018834,0.72189057,0.0018064118,0.2406273,0.009103609],"study_design_scores_gemma":[0.0059826067,0.0010091845,0.008030716,0.0013419498,0.00006907234,0.0009317844,0.0001788989,0.00054788264,0.9529964,0.0015890106,0.0268625,0.00046002987],"about_ca_topic_score_codex":0.00014259762,"about_ca_topic_score_gemma":0.000013592697,"teacher_disagreement_score":0.2311058,"about_ca_system_score_codex":0.00004284027,"about_ca_system_score_gemma":0.00008480098,"threshold_uncertainty_score":0.9997397},"labels":[],"label_agreement":null},{"id":"W2791558035","doi":"10.1016/j.celrep.2018.02.090","title":"Enteroviral Infection Inhibits Autophagic Flux via Disruption of the SNARE Complex to Enhance Viral Replication","year":2018,"lang":"en","type":"article","venue":"Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":143,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Luonnontieteiden ja Tekniikan Tutkimuksen Toimikunta; Natural Sciences and Engineering Research Council of Canada; University of British Columbia; ALS Society of Canada; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Cell biology; Biology; Viral replication; Picornavirus; Endosome; Autophagosome; Signal transducing adaptor protein; Coxsackievirus; Virology; Virus; Signal transduction; RNA; Enterovirus; Intracellular; Genetics","score_opus":0.013965037636154828,"score_gpt":0.30908207682261785,"score_spread":0.29511703918646304,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791558035","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925389,0.000053138974,0.0018687878,0.00022486955,0.00042224416,0.0005833636,0.000002123269,0.00006641407,0.0042401007],"genre_scores_gemma":[0.99610883,0.000005841488,0.00010017844,0.00076501764,0.0002485282,0.000032874363,0.00005336621,0.000017379985,0.0026679747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998828,0.000037906164,0.00039475004,0.00034311402,0.0002468172,0.00014941688],"domain_scores_gemma":[0.9985548,0.000010817377,0.00030267294,0.0008830525,0.0001592265,0.00008938154],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017369844,0.000116943476,0.0001702077,0.00005700933,0.000099130775,0.0000091127395,0.000050220908,0.00006786956,0.00029431726],"category_scores_gemma":[0.00007037858,0.00008738495,0.000113447924,0.00018850212,0.00009003529,0.00007756331,0.000049733528,0.000084795414,0.000054849916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011678594,0.00026991896,0.04728101,0.00007688118,0.000022294926,0.000026313219,0.000448791,0.0000052689857,0.939571,0.000016987817,0.0027537048,0.009411032],"study_design_scores_gemma":[0.00013213161,0.00025888562,0.31923854,0.000053841177,0.000034396733,0.00007009672,0.000005814122,0.000082663246,0.6745062,0.00025151283,0.0053047873,0.00006112059],"about_ca_topic_score_codex":0.00005776562,"about_ca_topic_score_gemma":0.000008731948,"teacher_disagreement_score":0.27195755,"about_ca_system_score_codex":0.0000735872,"about_ca_system_score_gemma":0.00005380748,"threshold_uncertainty_score":0.3563455},"labels":[],"label_agreement":null},{"id":"W2791640311","doi":"10.3389/fncel.2018.00039","title":"Vulnerable Parkin Loss-of-Function Drosophila Dopaminergic Neurons Have Advanced Mitochondrial Aging, Mitochondrial Network Loss and Transiently Reduced Autophagosome Recruitment","year":2018,"lang":"en","type":"article","venue":"Frontiers in Cellular Neuroscience","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Midwestern University","keywords":"Parkin; Mitophagy; Neurodegeneration; Biology; Mitochondrion; Cell biology; Substantia nigra; Drosophila melanogaster; PINK1; Dopaminergic; Neuroscience; Autophagy; Parkinson's disease; Genetics; Dopamine; Pathology; Medicine; Gene","score_opus":0.02277748907542069,"score_gpt":0.27518045925757606,"score_spread":0.25240297018215535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791640311","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9654157,0.0020999718,0.014321474,0.0005123056,0.015571377,0.0016097217,0.000017861998,0.000097238706,0.00035433838],"genre_scores_gemma":[0.99189514,0.00042490277,0.0041930163,0.00065208983,0.0014129148,0.00011200294,0.00002031738,0.00005554438,0.0012340979],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966454,0.00025442112,0.00063803676,0.0010779945,0.00062111893,0.0007630385],"domain_scores_gemma":[0.9985764,0.000057977555,0.00025333487,0.00067505275,0.00009776703,0.00033943573],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022598839,0.00038701762,0.0006166351,0.00027462552,0.0003367964,0.000053906253,0.0003283467,0.00016120153,0.00003420137],"category_scores_gemma":[0.00013577119,0.00037266378,0.00016430856,0.00075706694,0.0011092013,0.0003107668,0.000076719465,0.00045940792,0.0000041662965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002814359,0.0005583,0.008112554,0.00009418342,0.00003838797,0.0007187744,0.0006269491,0.0011268306,0.97828805,0.0002263337,0.00261563,0.0047796373],"study_design_scores_gemma":[0.028120404,0.009711089,0.061267763,0.0009488535,0.00075911474,0.00043832674,0.0002862589,0.045099627,0.74170446,0.009084348,0.10050209,0.0020776882],"about_ca_topic_score_codex":0.000015418264,"about_ca_topic_score_gemma":0.0000036726638,"teacher_disagreement_score":0.23658362,"about_ca_system_score_codex":0.0000880236,"about_ca_system_score_gemma":0.00019166477,"threshold_uncertainty_score":0.9998725},"labels":[],"label_agreement":null},{"id":"W2791770260","doi":"10.1016/j.bpj.2017.11.412","title":"Feedforward and Feedback Amplification in the Pink1-Parkin Pathway Generate a Binary Switch for Mitochondrial Quality Control in Parkinson Disease","year":2018,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Parkin; Mitophagy; PINK1; Mitochondrion; Cell biology; Ubiquitin ligase; Ubiquitin; Biology; Chemistry; Parkinson's disease; Autophagy; Biochemistry; Medicine; Disease; Internal medicine; Apoptosis; Gene","score_opus":0.02923862423238299,"score_gpt":0.31514557615263233,"score_spread":0.28590695192024934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791770260","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936963,0.00017860079,0.0017339751,0.0033141763,0.00025949973,0.0007190496,0.000047202215,0.000010286274,0.000040954048],"genre_scores_gemma":[0.9951327,0.00007363362,0.00021669542,0.001761628,0.002665073,0.00007611449,0.00002241628,0.000016747259,0.00003498681],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99852234,0.0002512977,0.00040360956,0.00025837173,0.00027139855,0.00029297],"domain_scores_gemma":[0.99912906,0.00016774354,0.00014808662,0.00022731356,0.00009178059,0.00023601369],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042361135,0.00016381517,0.00030226487,0.00008785545,0.00013306916,0.00007473179,0.00013370626,0.000080457205,0.000021520593],"category_scores_gemma":[0.000100309175,0.00010631098,0.0001333948,0.00018472363,0.0001541539,0.00010848089,0.000013196418,0.00027094316,0.0000289756],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0182279,0.0021246788,0.015887342,0.00010331415,0.00013441448,0.0001435778,0.0011634536,0.000008189806,0.94164807,0.0022970622,0.0020531232,0.01620887],"study_design_scores_gemma":[0.015865037,0.0011441617,0.9494283,0.0001663997,0.00012610799,0.000040032483,0.00021290539,0.004541684,0.0058657737,0.0045116036,0.017794792,0.0003031851],"about_ca_topic_score_codex":0.0000227516,"about_ca_topic_score_gemma":0.000009098223,"teacher_disagreement_score":0.9357823,"about_ca_system_score_codex":0.00006193036,"about_ca_system_score_gemma":0.00015032929,"threshold_uncertainty_score":0.4335236},"labels":[],"label_agreement":null},{"id":"W2792006925","doi":"","title":"The Role of BNIP3 in Proliferation and Hypoxia-Induced Autophagy: Implications for Cancer Therapy","year":2010,"lang":"en","type":"article","venue":"Mspace (University of Manitoba)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; U.S. Department of Defense","keywords":"Autophagy; Hypoxia (environmental); Cancer therapy; Cancer research; Cancer; Cell biology; Chemistry; Biology; Medicine; Oxygen; Apoptosis; Biochemistry; Internal medicine","score_opus":0.017471827269107915,"score_gpt":0.2550707892561385,"score_spread":0.2375989619870306,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792006925","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99437135,0.0005313637,0.000055836666,0.0041576014,0.000042952553,0.0005331385,0.00001518551,0.000013536533,0.00027900471],"genre_scores_gemma":[0.9990316,0.00049708475,0.00029308983,0.000047381876,0.000036663572,0.0000043602777,0.000004940286,0.0000065762574,0.000078317535],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99964696,0.000016365737,0.00006168692,0.00011061425,0.00006686037,0.00009751159],"domain_scores_gemma":[0.9995284,0.00006676087,0.00008038496,0.00018366438,0.00009816788,0.00004263512],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010789004,0.000059470003,0.00012664807,0.000055445646,0.00012173809,0.000004793137,0.00008545075,0.00006233323,0.00000454176],"category_scores_gemma":[0.000014609038,0.00005299408,0.000045749945,0.00009185226,0.00008484165,0.0000686055,0.0000161759,0.00008578566,7.1826935e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006298128,0.00020788077,0.28379294,0.00003170843,0.00010067414,0.0000011224823,0.0006034616,0.000002665069,0.6453909,0.010431857,0.00018751968,0.058619395],"study_design_scores_gemma":[0.0014923881,0.00013284646,0.9568109,0.000013938333,0.000029475152,0.0000017026379,0.0014686642,0.00045462628,0.032444358,0.0021022845,0.004997218,0.00005160264],"about_ca_topic_score_codex":0.000512966,"about_ca_topic_score_gemma":0.038190007,"teacher_disagreement_score":0.6730179,"about_ca_system_score_codex":0.000018443952,"about_ca_system_score_gemma":0.000092226765,"threshold_uncertainty_score":0.9793605},"labels":[],"label_agreement":null},{"id":"W2792125618","doi":"10.1016/j.ejphar.2018.02.042","title":"Interferon-stimulated gene 15 promotes cholesterol efflux by activating autophagy via the miR-17-5p/Beclin-1 pathway in THP-1 macrophage-derived foam cells","year":2018,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Libin Cardiovascular Institute of Alberta","funders":"National Natural Science Foundation of China","keywords":"Autophagy; ISG15; Efflux; ABCA1; Chemistry; Cholesterol; THP1 cell line; Cell biology; Macrophage; Downregulation and upregulation; Biology; Biochemistry; Cell culture; Transporter; Gene; In vitro; Ubiquitin; Apoptosis","score_opus":0.016486529445411187,"score_gpt":0.29255712213866614,"score_spread":0.27607059269325496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792125618","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931148,0.0009724075,0.0023308985,0.0011180768,0.0012425156,0.0005227555,0.000012810679,0.00005175382,0.00063397526],"genre_scores_gemma":[0.9929243,0.00008222433,0.0003867842,0.0044846213,0.0015438277,0.0000054701172,0.000008193287,0.0000999762,0.00046461893],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996369,0.0013976156,0.0010353074,0.00034147679,0.000298877,0.00055774045],"domain_scores_gemma":[0.9983073,0.00020265432,0.0006551532,0.00026764465,0.00028133427,0.0002859481],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0013371694,0.00035794362,0.00058259827,0.00020734585,0.00016725829,0.00003962149,0.0005612577,0.00008497677,0.001637486],"category_scores_gemma":[0.000063908745,0.00024814243,0.00021583526,0.00027081635,0.0003054545,0.00017447863,0.0001478568,0.0009946078,0.00020938335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013410497,0.0005683223,0.00016750257,0.000028105758,0.00040052948,0.0008973947,0.001552222,0.000100105404,0.97981024,4.87811e-7,0.0054136193,0.009720451],"study_design_scores_gemma":[0.00860784,0.0031253288,0.0041942936,0.00012882665,0.00014183843,0.00046038858,0.000070608556,0.0033141635,0.97289526,0.000014314908,0.0068319347,0.00021517396],"about_ca_topic_score_codex":0.0000072587704,"about_ca_topic_score_gemma":0.0000013447058,"teacher_disagreement_score":0.0095052775,"about_ca_system_score_codex":0.00012194832,"about_ca_system_score_gemma":0.00014628198,"threshold_uncertainty_score":0.9999971},"labels":[],"label_agreement":null},{"id":"W2792777003","doi":"10.1093/jcag/gwy008.265","title":"A264 AUTOPHAGY IS CRITICAL FOR GOBLET CELLS TO MAINTAIN HOMEOSTASIS UNDER HIGH METABOLIC STRESS","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Autophagy; Cell biology; AMPK; Biology; Goblet cell; ULK1; BECN1; Signal transduction; Chemistry; Unfolded protein response; Protein kinase A; Apoptosis; Kinase; Biochemistry; Endoplasmic reticulum","score_opus":0.010107873247030306,"score_gpt":0.2774239308527028,"score_spread":0.26731605760567245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792777003","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9205124,0.00005324375,0.00096003944,0.07671697,0.0009904196,0.00025075546,0.000428027,0.0000042734496,0.00008388863],"genre_scores_gemma":[0.9732568,0.0000179473,0.00090212724,0.024779981,0.00059139804,0.0000050409017,0.0000036654164,0.000018198145,0.0004248432],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998503,0.00017868716,0.00046551955,0.00011809125,0.00029837407,0.00043630792],"domain_scores_gemma":[0.9980063,0.0001285369,0.00043854569,0.0001963016,0.00076718704,0.00046315743],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005966151,0.000116928866,0.00045159113,0.00026278195,0.00012067464,0.000016773782,0.00023433514,0.00013175905,0.00036332573],"category_scores_gemma":[0.0002899697,0.00009095737,0.00027513356,0.00012424134,0.00009620803,0.000054234235,0.000021299233,0.00018321408,0.000011151751],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00972256,0.0013748922,0.54832375,0.00023951926,0.00801583,0.00013220706,0.002553309,0.00031139777,0.017646112,0.046663973,0.36150324,0.0035131918],"study_design_scores_gemma":[0.007407144,0.005761415,0.89409375,0.00015967122,0.0012083014,0.00010439281,0.00038298155,0.00008361477,0.051539686,0.004791661,0.034299064,0.00016831995],"about_ca_topic_score_codex":0.0014861436,"about_ca_topic_score_gemma":0.034099564,"teacher_disagreement_score":0.34576997,"about_ca_system_score_codex":0.00066329184,"about_ca_system_score_gemma":0.00049989397,"threshold_uncertainty_score":0.9835256},"labels":[],"label_agreement":null},{"id":"W2794392673","doi":"10.1158/0008-5472.can-17-2926","title":"2-Hydroxyglutarate-Mediated Autophagy of the Endoplasmic Reticulum Leads to an Unusual Downregulation of Phospholipid Biosynthesis in Mutant IDH1 Gliomas","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Cancer Foundation; University of Calgary","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institutes of Health","keywords":"Endoplasmic reticulum; Downregulation and upregulation; Autophagy; Mutant; IDH1; Cell biology; Biosynthesis; Phospholipid; Chemistry; Biology; Biochemistry; Enzyme; Gene; Apoptosis","score_opus":0.04535303779201242,"score_gpt":0.39577592531780903,"score_spread":0.3504228875257966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794392673","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997246,0.0003531146,0.0000055813825,0.00079385977,0.00014337129,0.00077491725,0.000066097826,0.000022092856,0.0005949376],"genre_scores_gemma":[0.9992267,0.00009375762,0.000035103087,0.00012586002,0.00021084647,0.00008843273,0.000009044367,0.00003036474,0.00017992716],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976875,0.00029047663,0.00040938144,0.00034090143,0.00081608817,0.00045562797],"domain_scores_gemma":[0.9984041,0.00015909651,0.00009632303,0.0006566997,0.00048066082,0.00020311773],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082179456,0.00014138584,0.00034603683,0.00042630942,0.00008419018,0.000009920517,0.00032863414,0.0001289133,0.0007050894],"category_scores_gemma":[0.00032490998,0.000100462545,0.00008314646,0.001816989,0.00065324607,0.000084364525,0.00009510362,0.00024712275,0.000041371975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012191241,0.00024704574,0.0078893015,0.00007960749,0.00004428198,0.00001533006,0.0013506429,0.000041388612,0.98666734,0.00029853368,0.00014279372,0.002004591],"study_design_scores_gemma":[0.0010580114,0.0006158975,0.12055676,0.00026409136,0.000019423538,0.0000040997675,0.00014418694,0.0007692876,0.87584955,0.00015921258,0.00047601512,0.00008348635],"about_ca_topic_score_codex":0.0009310765,"about_ca_topic_score_gemma":0.00031507193,"teacher_disagreement_score":0.11266745,"about_ca_system_score_codex":0.00020187936,"about_ca_system_score_gemma":0.0006568986,"threshold_uncertainty_score":0.7720235},"labels":[],"label_agreement":null},{"id":"W2794417476","doi":"10.1007/978-1-4939-7765-9_10","title":"Autophagic Flux Assessment in Colorectal Cancer Cells","year":2018,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Autophagosome; Flux (metallurgy); Colorectal cancer; Cell biology; Programmed cell death; Cancer research; Cancer; Chemistry; Biology; Medicine; Biochemistry; Internal medicine; Apoptosis","score_opus":0.021510605565721444,"score_gpt":0.458984807861057,"score_spread":0.43747420229533557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794417476","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83357877,0.0011359609,0.16025467,0.000296559,0.0005477172,0.00038125867,0.000006085884,0.00003500782,0.0037639912],"genre_scores_gemma":[0.5003012,0.00009235651,0.4971065,0.0019933435,0.00013624024,0.00014484506,0.000016451255,0.000025564234,0.00018348772],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99818027,0.0007623048,0.00028276924,0.00035932413,0.000073206196,0.0003421203],"domain_scores_gemma":[0.9995023,0.00009683663,0.000058179736,0.00022059193,0.000041803527,0.00008028872],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007334649,0.00015520863,0.00037864337,0.00020501604,0.000022615888,0.0000045179745,0.00012424913,0.00020792747,0.0009459848],"category_scores_gemma":[0.00005437619,0.0001339195,0.00008074449,0.0003012853,0.00021631943,0.000014241525,0.000058055008,0.00027801187,0.000022423943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011244347,0.00015096355,0.009614662,0.000012616126,0.00004787755,0.0001406187,0.00012979048,0.000005360399,0.9703544,0.0011514911,0.000039754996,0.018240029],"study_design_scores_gemma":[0.0015069464,0.0004571958,0.044644684,0.000032080614,0.000020070227,0.000008621187,0.000030517804,0.000913617,0.94545823,0.005050317,0.0017430892,0.00013460935],"about_ca_topic_score_codex":0.00014191358,"about_ca_topic_score_gemma":0.00003211082,"teacher_disagreement_score":0.33685184,"about_ca_system_score_codex":0.00014749762,"about_ca_system_score_gemma":0.00021895858,"threshold_uncertainty_score":0.9999673},"labels":[],"label_agreement":null},{"id":"W2794765381","doi":"10.1038/s41467-018-03658-2","title":"Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":199,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada; Western University","funders":"Agriculture and Agri-Food Canada; Natural Sciences and Engineering Research Council of Canada; Tsinghua University","keywords":"Autophagy; Viral replication; Biology; Virology; RNA; Polymerase; Viral protein; Viral entry; Cell biology; Virus; RNA-dependent RNA polymerase; RNA virus; Viral structural protein; RNA polymerase; Genetics; Gene","score_opus":0.02755456442999668,"score_gpt":0.3469861025317471,"score_spread":0.3194315381017504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794765381","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911612,0.0050214212,0.000020303163,0.0015139398,0.00013056038,0.00023700525,0.00002055507,0.000020075362,0.0018749258],"genre_scores_gemma":[0.9949273,0.0038896038,0.00041302777,0.000569475,0.000049248836,0.00001203848,0.000057396155,0.0000074242525,0.000074521886],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9994228,0.00011766214,0.0001690092,0.00009351387,0.0001192562,0.00007779277],"domain_scores_gemma":[0.99886173,0.0001055545,0.00009719363,0.0008479773,0.000059695896,0.0000278761],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008483095,0.00006780556,0.00010368502,0.00006045782,0.00016026155,0.0000061800793,0.00016205056,0.00016818388,0.000014674117],"category_scores_gemma":[0.000116210555,0.000047366255,0.000033653378,0.00022284413,0.00018262978,0.000107322725,0.00011176295,0.0004143131,0.0000025407126],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010234795,0.0021438561,0.5897879,0.00007934765,0.00018197135,0.0000051686166,0.0035646725,0.000003862992,0.34678075,0.016352158,0.008003079,0.032073755],"study_design_scores_gemma":[0.0009956138,0.000090623034,0.82453305,0.0001606117,0.00004134702,0.000009242539,0.00003063823,0.00028889123,0.16793253,0.001217538,0.004637138,0.00006276952],"about_ca_topic_score_codex":0.0004961221,"about_ca_topic_score_gemma":0.0008712369,"teacher_disagreement_score":0.23474517,"about_ca_system_score_codex":0.00002808887,"about_ca_system_score_gemma":0.00005758457,"threshold_uncertainty_score":0.19315398},"labels":[],"label_agreement":null},{"id":"W2794812256","doi":"10.1016/j.ebiom.2018.03.028","title":"Trans-Fats Inhibit Autophagy Induced by Saturated Fatty Acids","year":2018,"lang":"en","type":"article","venue":"EBioMedicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Labex Immuno-Oncology; European Research Council; BioTechMed-Graz; Institut National Du Cancer; Institut Universitaire de France; Institute of Cancer Research; Labex; Ligue Contre le Cancer; Agence Nationale de la Recherche; Fondation ARC pour la Recherche sur le Cancer; Cancer Research Institute; Bundesministerium für Wissenschaft, Forschung und Wirtschaft; Fondation pour la Recherche Médicale; Association pour la Recherche sur le Cancer; Seerave Foundation; Fondation Leducq; European Commission; Institut Mérieux; Austrian Science Fund","keywords":"Elaidic acid; Autophagy; Palmitic acid; Saturated fatty acid; Fatty acid; Oleic acid; Biochemistry; Peroxisome; Unsaturated fatty acid; Chemistry; Biology; Endoplasmic reticulum; Linoleic acid; Gene; Apoptosis","score_opus":0.01727925116431737,"score_gpt":0.2974125586034351,"score_spread":0.2801333074391177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794812256","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98551786,0.0015262858,0.0007049216,0.004413292,0.0007541665,0.00051961455,0.00003597407,0.00036481884,0.006163047],"genre_scores_gemma":[0.989818,0.000086573746,0.00023004919,0.0061130035,0.0014665693,0.000023817382,0.0002910827,0.00005588701,0.0019150176],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99804616,0.000051562092,0.00043367431,0.00045779793,0.00050918385,0.0005016172],"domain_scores_gemma":[0.9986684,0.000040255953,0.00009781377,0.0005223353,0.00019008378,0.00048113443],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022009469,0.00031759535,0.0005237574,0.00021644484,0.00014093363,0.000014689057,0.00016188265,0.00024966607,0.0027622043],"category_scores_gemma":[0.00005808459,0.00023977377,0.00011603396,0.0007518889,0.00041638935,0.000104005274,0.000024903195,0.0003152982,0.00029345814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006139641,0.0003268871,0.0006034322,0.0000524599,0.00021234712,0.00013118745,0.0008718303,1.5814193e-8,0.9514038,0.000060867114,0.02496292,0.020760288],"study_design_scores_gemma":[0.011352253,0.0034688602,0.06516363,0.0003395742,0.00030167282,0.00012859402,0.00019198883,0.0001362529,0.8141306,0.0003397006,0.10400963,0.00043726648],"about_ca_topic_score_codex":0.000049098206,"about_ca_topic_score_gemma":0.0000030229573,"teacher_disagreement_score":0.13727322,"about_ca_system_score_codex":0.00008492117,"about_ca_system_score_gemma":0.00015188308,"threshold_uncertainty_score":0.9981494},"labels":[],"label_agreement":null},{"id":"W2794915225","doi":"10.1016/j.bbamcr.2018.03.011","title":"TRIM50 regulates Beclin 1 proautophagic activity","year":2018,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Instytut Biologii Medycznej Polskiej Akademii Nauk; Fondazione Telethon; Associazione Italiana per la Ricerca sul Cancro; Fondation Jérôme Lejeune; Ministry of Health, British Columbia; Ministero della Salute","keywords":"Autophagy; Ubiquitin; Cell biology; Ubiquitin ligase; Acetylation; ULK1; BAG3; Chemistry; Endogeny; Biology; Biochemistry; Phosphorylation; Protein kinase A; Apoptosis","score_opus":0.051587602857010514,"score_gpt":0.3885650808652394,"score_spread":0.33697747800822886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794915225","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9800053,0.0004408219,0.000061131475,0.0034672944,0.00015047794,0.0013784086,0.000029827277,0.0002121391,0.014254549],"genre_scores_gemma":[0.9939611,0.00025013316,0.00054388546,0.0007723001,0.0005881433,0.00011547458,0.00008061336,0.00013889183,0.0035494408],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9950229,0.0007093206,0.00040138295,0.0011290357,0.0015490415,0.001188324],"domain_scores_gemma":[0.99679214,0.00021421163,0.00014928842,0.0016128679,0.00061354716,0.00061793503],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010155817,0.00046694055,0.0006027548,0.00048432153,0.00038729,0.00015076775,0.00063569605,0.00034505528,0.00037833655],"category_scores_gemma":[0.00015580513,0.0004066796,0.0004366942,0.0013048408,0.0010834199,0.00017739649,0.0003668066,0.0010118171,0.0009131892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013337146,0.0014891506,0.000004665566,0.00014218966,0.00021572392,0.00024048336,0.00033231865,2.3837008e-7,0.99057204,0.00031209903,0.0026593388,0.0026980708],"study_design_scores_gemma":[0.002067963,0.0017279385,0.004490108,0.0001039746,0.000105594416,0.000016827855,0.00005368985,0.00040810293,0.9868366,0.0012633079,0.002535814,0.00039006508],"about_ca_topic_score_codex":0.000080756785,"about_ca_topic_score_gemma":0.0000019586846,"teacher_disagreement_score":0.013955766,"about_ca_system_score_codex":0.00017139492,"about_ca_system_score_gemma":0.00083168375,"threshold_uncertainty_score":0.9998647},"labels":[],"label_agreement":null},{"id":"W2795030274","doi":"10.1186/s13098-018-0317-6","title":"Up-regulated autophagy: as a protective factor in adipose tissue of WOKW rats with metabolic syndrome","year":2018,"lang":"en","type":"article","venue":"Diabetology & Metabolic Syndrome","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"Autophagy; Adiponectin; Internal medicine; Adipokine; Endocrinology; Adipose tissue; Inflammation; Medicine; Adipocyte; Apoptosis; Tumor necrosis factor alpha; Leptin; Biology; Diabetes mellitus; Insulin resistance; Obesity; Biochemistry","score_opus":0.011434065808093552,"score_gpt":0.27988204869742866,"score_spread":0.26844798288933513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2795030274","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9851149,0.011152497,0.000047463982,0.0002422119,0.00049847417,0.0021740654,0.000098321696,0.00021806113,0.0004540282],"genre_scores_gemma":[0.9971767,0.00013729524,0.00036552112,0.00054193015,0.00009907308,0.00044708146,0.000062947205,0.00012260547,0.0010468537],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99616665,0.00041466684,0.0008678202,0.00094476214,0.00056625705,0.00103985],"domain_scores_gemma":[0.9975516,0.00012170228,0.000417898,0.0011126993,0.00034839433,0.00044766054],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003573663,0.0006609721,0.0029013052,0.0009501598,0.00011885705,0.00001842286,0.00042247327,0.00050864596,0.0019360826],"category_scores_gemma":[0.00018016207,0.0005275307,0.00022659558,0.0016584097,0.0010125531,0.00027048116,0.000104046936,0.0005519176,0.00042185586],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011199185,0.0112376,0.2518831,0.0012997938,0.03227382,0.028542088,0.024516316,0.000033598182,0.50860316,0.034168366,0.0004594568,0.09578353],"study_design_scores_gemma":[0.005128401,0.002464407,0.77751017,0.00020194607,0.00077939173,0.004083543,0.00010244595,0.000038439306,0.20443588,0.0016908613,0.0030712658,0.00049325137],"about_ca_topic_score_codex":0.0004433606,"about_ca_topic_score_gemma":0.000048448353,"teacher_disagreement_score":0.5256271,"about_ca_system_score_codex":0.00006073138,"about_ca_system_score_gemma":0.0005805346,"threshold_uncertainty_score":0.99971765},"labels":[],"label_agreement":null},{"id":"W2796296273","doi":"10.1007/s10637-018-0595-8","title":"Autophagy inhibition improves the chemotherapeutic efficacy of cruciferous vegetable-derived diindolymethane in a murine prostate cancer xenograft model","year":2018,"lang":"en","type":"article","venue":"Investigational New Drugs","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; In vivo; Prostate cancer; Apoptosis; Programmed cell death; Cancer research; Medicine; Cancer; Pharmacology; Prostate; TUNEL assay; Growth inhibition; Internal medicine; Biology; Immunohistochemistry; Biochemistry","score_opus":0.02092564730317531,"score_gpt":0.2962967590629427,"score_spread":0.2753711117597674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2796296273","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919011,0.0017214812,0.00013611025,0.004939881,0.000094377654,0.000761733,0.000019748268,0.000063206615,0.000362359],"genre_scores_gemma":[0.99289507,0.0001287875,0.001112075,0.004158752,0.0003829784,0.000097830576,0.00004864398,0.000039460585,0.0011363849],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984944,0.00005573347,0.0004491111,0.00031012515,0.00040294026,0.0002876818],"domain_scores_gemma":[0.99903053,0.00011066217,0.00020002437,0.000302658,0.00016689053,0.00018924975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001921155,0.00021520753,0.00031321924,0.00014260951,0.00008013895,0.000017349073,0.00012030284,0.000092719514,0.00012668721],"category_scores_gemma":[0.00006873667,0.00015965034,0.000103624836,0.00042743838,0.0005572409,0.00014387604,0.00003789998,0.00018978809,0.000017596103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013393025,0.0005064304,0.0020804303,0.00016572587,0.0002576614,0.000010299565,0.009751091,0.0011308835,0.9646097,0.0023656357,0.0003825206,0.017400326],"study_design_scores_gemma":[0.007640349,0.00024618162,0.07513829,0.00042160126,0.00011805699,0.000014892054,0.000078977384,0.019438133,0.87263453,0.023845145,0.00019598796,0.00022785335],"about_ca_topic_score_codex":0.00048675083,"about_ca_topic_score_gemma":0.00003888016,"teacher_disagreement_score":0.09197517,"about_ca_system_score_codex":0.00008105708,"about_ca_system_score_gemma":0.0009880316,"threshold_uncertainty_score":0.6510352},"labels":[],"label_agreement":null},{"id":"W2796906206","doi":"10.1016/j.molcel.2018.03.012","title":"Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics","year":2018,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":197,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Michael J. Fox Foundation for Parkinson's Research","keywords":"Parkin; Mitophagy; Biology; Cell biology; Ubiquitin ligase; Ubiquitin; PINK1; Phosphorylation; Endocytic cycle; Ubiquitin-Protein Ligases; Mitochondrion; Signal transduction; Biochemistry; Endocytosis; Receptor; Autophagy; Apoptosis","score_opus":0.008914647816676866,"score_gpt":0.24047765540907154,"score_spread":0.23156300759239468,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2796906206","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98922247,0.00019809927,0.007901191,0.000080566235,0.0001037919,0.0008321548,0.00005127056,0.00001501648,0.0015954584],"genre_scores_gemma":[0.9992398,0.0000150644455,0.00025926338,0.00007245456,0.000048541555,0.000028615104,0.00014964349,0.000025335117,0.00016128537],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999072,0.000037627018,0.00027417447,0.00023900672,0.0002116284,0.00016557227],"domain_scores_gemma":[0.9994732,0.000011732802,0.00010639107,0.00025137278,0.00006234853,0.00009495515],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000060794275,0.00013078806,0.00023361981,0.00008029107,0.000022985641,0.000025081834,0.00006772729,0.000117201576,0.000006845663],"category_scores_gemma":[0.000023382741,0.00012846211,0.000047825633,0.000096533,0.00005528812,0.00006607737,0.000037862057,0.00012306438,0.0000025862996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004525143,0.0003192022,0.002511073,0.00014312471,0.00003707423,0.00005339073,0.0002170872,0.00023053176,0.9954715,0.0002140965,0.000095352916,0.000255092],"study_design_scores_gemma":[0.0075479886,0.0012530279,0.0018862488,0.00020258484,0.00016538179,0.000026163352,0.00011848598,0.4094407,0.5775487,0.0013133936,0.00007017517,0.0004271805],"about_ca_topic_score_codex":0.000028248985,"about_ca_topic_score_gemma":0.0000045007614,"teacher_disagreement_score":0.4179228,"about_ca_system_score_codex":0.000056072244,"about_ca_system_score_gemma":0.00007722153,"threshold_uncertainty_score":0.52385324},"labels":[],"label_agreement":null},{"id":"W2797278894","doi":"10.1139/cjpp-2018-0021","title":"Imidazolines increase the levels of the autophagosomal marker LC3-II in macrophage-like RAW264.7 cells","year":2018,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Japan Society for the Promotion of Science","keywords":"Idazoxan; Bafilomycin; Autophagy; Autophagosome; Imidazoline receptor; Chemistry; Lysosome; Cell biology; Pharmacology; Biology; Biochemistry; Receptor; Antagonist; Enzyme","score_opus":0.012920490120756007,"score_gpt":0.2777903888939553,"score_spread":0.2648698987731993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2797278894","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99428654,0.0017474951,0.0000013203254,0.001976576,0.0014947408,0.00018816577,0.00003788344,0.000002368349,0.0002649122],"genre_scores_gemma":[0.99260587,0.00010745868,0.00002155731,0.006129808,0.0007865653,0.0000039245447,0.0000010389263,0.000012092515,0.00033166452],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875873,0.0003321941,0.0003767655,0.00013590862,0.0000743322,0.00032208688],"domain_scores_gemma":[0.99895746,0.00014686468,0.00024227874,0.00016544238,0.00016938643,0.00031856392],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00033606862,0.00014326732,0.00036071966,0.00014732927,0.0002282317,0.0000034075188,0.00027122296,0.00014092145,0.0035723636],"category_scores_gemma":[0.000032350046,0.00008157013,0.00012594345,0.00018933832,0.0011521224,0.000050834158,0.000042073625,0.00042116232,0.000005962554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007659052,0.000081125945,0.0062929466,0.000048528935,0.0002547848,0.00018032578,0.00081433076,0.000016088006,0.9837697,0.00012340427,0.006577065,0.0010757629],"study_design_scores_gemma":[0.0034020215,0.0006038597,0.46974346,0.00004932,0.00024652545,0.00040485192,0.000085680425,0.00015989118,0.51265544,0.0015043928,0.011029059,0.00011549149],"about_ca_topic_score_codex":0.0006221805,"about_ca_topic_score_gemma":0.00077491376,"teacher_disagreement_score":0.47111428,"about_ca_system_score_codex":0.000040550367,"about_ca_system_score_gemma":0.0010724411,"threshold_uncertainty_score":0.99733853},"labels":[],"label_agreement":null},{"id":"W2797510526","doi":"10.1101/298729","title":"STF-62247 blocks late stages of autophagy by disrupting lysosomal physiology","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Atlantic Cancer Research Institute; Université de Moncton","funders":"","keywords":"Autophagy; Endocytic cycle; ATG5; Cell biology; BECN1; Lysosome; Cathepsin D; Biology; Phenotype; Endosome; Autophagosome; Chemistry; Cell; Endocytosis; Gene; Biochemistry; Intracellular","score_opus":0.01146461575892443,"score_gpt":0.25165693248494053,"score_spread":0.2401923167260161,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2797510526","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929211,0.0038807825,0.00016702295,0.00014387716,0.0009696313,0.00080756523,0.0006264742,0.00044777046,0.000035785975],"genre_scores_gemma":[0.99615526,0.0005935777,0.0014290594,0.00044250768,0.0009889109,0.00012209117,0.0000035603637,0.00019405599,0.000070948525],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963977,0.0001698825,0.0009016223,0.0012131257,0.000524023,0.0007936576],"domain_scores_gemma":[0.9962251,0.0000973859,0.00083836616,0.0017862329,0.00061057345,0.00044229615],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042356926,0.0007623619,0.0013361519,0.00027358293,0.00014985948,0.000052785646,0.00055513467,0.000857495,0.0005443767],"category_scores_gemma":[0.00017969382,0.00074277323,0.00038982497,0.00037233141,0.00047254175,0.00010281274,0.0005272764,0.00087158964,0.00007859536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002494322,0.00050982414,0.008182405,0.0009330864,0.0008537272,0.00009979075,0.00002482268,0.000013785951,0.98775923,0.000106539475,0.0012617994,0.0000055778587],"study_design_scores_gemma":[0.0016723527,0.00032227975,0.16951057,0.0006696024,0.00050281116,4.598129e-8,0.0000035200956,0.00033777117,0.8234285,0.000010126003,0.0028324814,0.0007099219],"about_ca_topic_score_codex":0.00005107447,"about_ca_topic_score_gemma":4.1487533e-7,"teacher_disagreement_score":0.16433069,"about_ca_system_score_codex":0.00018038471,"about_ca_system_score_gemma":0.00074579695,"threshold_uncertainty_score":0.9995023},"labels":[],"label_agreement":null},{"id":"W2797881282","doi":"10.14288/1.0349027","title":"Investigating autophagy modulation in breast cancer","year":2020,"lang":"en","type":"article","venue":"cIRcle (University of British Columbia)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Breast cancer; Autophagy; Medicine; Cancer; Biology; Internal medicine; Genetics; Apoptosis","score_opus":0.013681815719152194,"score_gpt":0.20932450866950217,"score_spread":0.19564269295034997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2797881282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976147,0.00019114913,0.000077693214,0.0013752183,0.000033156342,0.00016971865,0.00009168229,0.000058468766,0.00038823864],"genre_scores_gemma":[0.99878883,0.00010467518,0.00021832914,0.00070946495,0.00005485049,4.8108245e-7,0.000018043953,0.000010288353,0.00009505063],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9993692,0.000024426838,0.0000941578,0.000220695,0.00015825898,0.00013327735],"domain_scores_gemma":[0.9995904,0.000010572126,0.00006807444,0.000099252116,0.000061296334,0.00017040764],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000045253557,0.000029252336,0.0002003345,0.000023641544,0.0000589488,0.000016014304,0.00008386345,0.000065425476,0.00035838303],"category_scores_gemma":[0.000012547077,0.000105699175,0.000066180735,0.00029045733,0.00010413858,0.00016336002,0.000035502613,0.000108910506,0.000010202289],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037873586,0.00013176407,0.41650602,0.00019924618,0.00006324953,0.00034639493,0.0008353043,0.00013396186,0.006436991,0.0000027280114,0.0014932102,0.57381326],"study_design_scores_gemma":[0.0017279454,0.000038179594,0.98993856,0.00021311535,0.000030204712,0.00002863656,0.00040285214,0.0073528113,0.000007622357,0.00012600687,0.000045550496,0.00008850734],"about_ca_topic_score_codex":0.053328108,"about_ca_topic_score_gemma":0.017163595,"teacher_disagreement_score":0.57372475,"about_ca_system_score_codex":0.000058059533,"about_ca_system_score_gemma":0.00012258049,"threshold_uncertainty_score":0.95776886},"labels":[],"label_agreement":null},{"id":"W2798453029","doi":"10.1101/306969","title":"Exocyst subcomplex functions in autophagosome biogenesis by regulating Atg9 trafficking","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"The Wellcome Trust DBT India Alliance; Jawaharlal Nehru Centre for Advanced Scientific Research; University of Toronto; Georg-August-Universität Göttingen; Department of Biotechnology, Ministry of Science and Technology, India; University of Alberta; Wellcome Trust","keywords":"Exocyst; Autophagy; Cell biology; Autophagosome; Biogenesis; Vesicle; Exocytosis; Biology; Golgi apparatus; Vacuole; Chemistry; Membrane; Biochemistry; Cytoplasm; Apoptosis; Endoplasmic reticulum","score_opus":0.01942417378367307,"score_gpt":0.24650547804672102,"score_spread":0.22708130426304796,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2798453029","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914333,0.004188667,0.0005076823,0.00026929087,0.0012078132,0.0010936679,0.0004614764,0.00080036273,0.000037715286],"genre_scores_gemma":[0.99555755,0.00018271977,0.002021329,0.00043099726,0.0012185171,0.00028823366,0.0000056373583,0.00025256578,0.000042465523],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99596596,0.00017544156,0.00096289685,0.0014190888,0.00059306313,0.0008835698],"domain_scores_gemma":[0.9968198,0.00010014013,0.0004947928,0.0017060997,0.00039217,0.00048697545],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000579409,0.0008012998,0.001070154,0.0006208989,0.0002686272,0.00014543867,0.00044875342,0.00079844217,0.00041502417],"category_scores_gemma":[0.00018955709,0.00086443085,0.00037314487,0.0009439561,0.00025744838,0.00015778125,0.00030755426,0.00081265124,0.00019169995],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002892915,0.00083223457,0.039483618,0.0008860098,0.00061541516,0.00027628432,0.000043423057,0.00007496388,0.95384383,0.00015540191,0.0034788416,0.000020657708],"study_design_scores_gemma":[0.0039196946,0.00027376498,0.6005189,0.0019394658,0.0006652372,2.7577804e-7,0.000018695238,0.0027108372,0.37967157,0.0000097611455,0.008437156,0.0018346444],"about_ca_topic_score_codex":0.000106339234,"about_ca_topic_score_gemma":0.00000481819,"teacher_disagreement_score":0.5741723,"about_ca_system_score_codex":0.00059358584,"about_ca_system_score_gemma":0.00081121223,"threshold_uncertainty_score":0.99938065},"labels":[],"label_agreement":null},{"id":"W2800197308","doi":"10.7554/elife.32866","title":"Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy","year":2018,"lang":"en","type":"article","venue":"eLife","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":369,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Medical Research Council; Genome Canada; McGill University","keywords":"Mitophagy; MFN2; Parkin; PINK1; Mitochondrion; VDAC1; Cell biology; Ubiquitin ligase; Autophagy; Ubiquitin; Biology; FIS1; Chemistry; mitochondrial fusion; Biochemistry; Bacterial outer membrane; Apoptosis; Mitochondrial DNA; Medicine","score_opus":0.007891319653139247,"score_gpt":0.27528517809705716,"score_spread":0.2673938584439179,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2800197308","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925571,0.0016006201,0.00062339765,0.0024590571,0.0005046695,0.00052360405,0.00010425548,0.000061338826,0.0015659562],"genre_scores_gemma":[0.9911675,0.00009353571,0.00037020977,0.005046586,0.0011544849,0.000051904823,0.000085932385,0.000029938336,0.001999951],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859715,0.00007910864,0.00031213686,0.00028952505,0.00049570034,0.00022640439],"domain_scores_gemma":[0.9988079,0.000118838805,0.0001273925,0.00049547723,0.0002461209,0.00020426603],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00013014296,0.00016065601,0.00024968167,0.00005960256,0.000095398645,0.000016734659,0.00019211484,0.00009170719,0.0012848476],"category_scores_gemma":[0.00019028355,0.000113729555,0.000102104954,0.00015814317,0.000120118464,0.00006029432,0.000052962387,0.00012613952,0.00051835924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013558067,0.0006661634,0.005246226,0.000035683566,0.00052691344,0.00004716344,0.0035197781,0.0000043200866,0.6685617,0.0007771452,0.30834168,0.010917415],"study_design_scores_gemma":[0.0016533075,0.0005774257,0.030234758,0.00011309609,0.00012849369,0.000003952408,0.00028165383,0.00011462423,0.9243035,0.00065170234,0.041775566,0.00016196897],"about_ca_topic_score_codex":0.00021299672,"about_ca_topic_score_gemma":0.000025277284,"teacher_disagreement_score":0.2665661,"about_ca_system_score_codex":0.00004787491,"about_ca_system_score_gemma":0.00008517101,"threshold_uncertainty_score":0.9996281},"labels":[],"label_agreement":null},{"id":"W2800633908","doi":"10.1101/320341","title":"HIV-1 antisense protein of different clades induces autophagy and associates to the autophagy factor p62","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Autophagy; ATG5; Immunoprecipitation; Autophagosome; Cell biology; Western blot; Biology; Flow cytometry; Molecular biology; ATG8; Gene; Chemistry; Genetics; Apoptosis","score_opus":0.01639998342845923,"score_gpt":0.24814824238725844,"score_spread":0.23174825895879922,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2800633908","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99248004,0.0026233091,0.00009827835,0.00088640157,0.0007335373,0.0022461677,0.000625541,0.00029713727,0.000009596003],"genre_scores_gemma":[0.99718934,0.00028900933,0.00070580916,0.00047403522,0.0008384365,0.00030893498,0.0000011303501,0.00014573665,0.000047576243],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967345,0.00023612984,0.0007341738,0.0010008829,0.00065818656,0.00063611096],"domain_scores_gemma":[0.9968276,0.00011709494,0.00060537533,0.0014370446,0.00052057573,0.00049229484],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003687467,0.00074117404,0.0011518834,0.00029885498,0.00020626806,0.00014350277,0.00050214125,0.00065788475,0.00016095184],"category_scores_gemma":[0.00037249477,0.0005421342,0.00026474515,0.0003603656,0.0003189581,0.000088811,0.00057859893,0.0007721466,0.00006593568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019217916,0.000452913,0.0077064238,0.0007577951,0.0008335279,0.000084722764,0.00011613224,0.0000014590246,0.9888817,0.00033637104,0.00062024716,0.000016494367],"study_design_scores_gemma":[0.0006428763,0.0002030209,0.4101819,0.00062481104,0.00020571443,4.2087077e-8,0.0000052973555,0.000050344737,0.5870416,0.000008646696,0.00067870144,0.0003570062],"about_ca_topic_score_codex":0.000039848168,"about_ca_topic_score_gemma":0.0000018120002,"teacher_disagreement_score":0.40247548,"about_ca_system_score_codex":0.00020479233,"about_ca_system_score_gemma":0.0005460231,"threshold_uncertainty_score":0.999703},"labels":[],"label_agreement":null},{"id":"W2800843754","doi":"10.1186/s13395-018-0157-y","title":"Role of Parkin and endurance training on mitochondrial turnover in skeletal muscle","year":2018,"lang":"en","type":"article","venue":"Skeletal Muscle","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Parkin; Training (meteorology); Skeletal muscle; Endurance training; Physical medicine and rehabilitation; Cell biology; Bioinformatics; Biology; Medicine; Anatomy; Endocrinology; Internal medicine","score_opus":0.01382595209505678,"score_gpt":0.26575199955029055,"score_spread":0.2519260474552338,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2800843754","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913068,0.0006170663,0.000011110818,0.00014160734,0.00026336056,0.00029209672,0.000017969602,0.000037390902,0.0073126378],"genre_scores_gemma":[0.99843216,0.00004094151,0.00022988312,0.00035820063,0.0007273746,0.00001985023,0.000010466863,0.00002880618,0.00015233144],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987792,0.000043521748,0.0002838296,0.00032346876,0.00025602014,0.00031400222],"domain_scores_gemma":[0.99939555,0.00006175107,0.00008512887,0.0002788759,0.00004318196,0.00013553452],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000101781545,0.0001756576,0.00033272154,0.00011897505,0.000049164926,0.000009776718,0.00008788808,0.00014831881,0.00032262073],"category_scores_gemma":[0.000057342066,0.00015710869,0.000109951354,0.00019983426,0.00025901094,0.000099153694,0.000022879625,0.00024559486,0.000039275972],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003130114,0.0005840494,0.0012645317,0.00008189586,0.00009695253,0.000063830885,0.005347649,0.0000028149757,0.7120533,0.0017603284,0.00024107234,0.27819058],"study_design_scores_gemma":[0.004643535,0.00083298417,0.9279767,0.00025035927,0.00004750491,0.000014007807,0.00050456286,0.00026090475,0.01973985,0.0011720944,0.044296883,0.00026057952],"about_ca_topic_score_codex":0.000047087175,"about_ca_topic_score_gemma":0.000046628764,"teacher_disagreement_score":0.9267122,"about_ca_system_score_codex":0.0000279903,"about_ca_system_score_gemma":0.00006139063,"threshold_uncertainty_score":0.64067066},"labels":[],"label_agreement":null},{"id":"W2801288479","doi":"10.2147/ott.s151751","title":"Role of Beclin1 expression in patients with hepatocellular carcinoma: a meta-analysis","year":2018,"lang":"en","type":"article","venue":"OncoTargets and Therapy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Capital Foundation of Medical Development","keywords":"Hepatocellular carcinoma; Medicine; Meta-analysis; Internal medicine; Cirrhosis; Hazard ratio; Oncology; Confidence interval; Odds ratio; Cochrane Library; Biomarker; Stage (stratigraphy); Gastroenterology; Biology","score_opus":0.020521972521979383,"score_gpt":0.2598492306203965,"score_spread":0.23932725809841712,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2801288479","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98749655,0.011683975,0.000028388537,0.000048504724,0.000011624614,0.00030285877,0.000014884784,0.000011754434,0.00040146778],"genre_scores_gemma":[0.9989314,0.00020548167,0.00043375226,0.00023384509,0.000039131486,0.00002047706,0.000030056373,0.00001669984,0.00008913794],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990812,0.000047394366,0.00022831943,0.0002484677,0.00023427751,0.00016036052],"domain_scores_gemma":[0.9993557,0.000020034024,0.000107276894,0.00030103643,0.00011873598,0.00009726845],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000115562056,0.00015374727,0.0006909426,0.00016040825,0.000043137046,0.0000062482163,0.00005593436,0.00006148605,0.00068944227],"category_scores_gemma":[0.0000030578958,0.00008924586,0.00024979073,0.00028870584,0.0000996582,0.000058061323,0.000013839229,0.00006875541,0.0000028408049],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013924844,0.00067002093,0.98112524,0.00000816866,0.01092481,0.000007378309,0.00068963954,7.0172507e-7,0.003910402,0.000034494242,0.000014539905,0.0012221121],"study_design_scores_gemma":[0.0044879443,0.001482021,0.9384807,0.000007864678,0.008967866,5.2441646e-7,0.000056161767,0.0002359739,0.044251006,0.00034997432,0.0015360162,0.00014395373],"about_ca_topic_score_codex":0.00009577331,"about_ca_topic_score_gemma":0.000010780578,"teacher_disagreement_score":0.042644557,"about_ca_system_score_codex":0.000010041048,"about_ca_system_score_gemma":0.000032341755,"threshold_uncertainty_score":0.7548909},"labels":[],"label_agreement":null},{"id":"W2801628465","doi":"10.1016/j.molcel.2018.03.037","title":"Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy","year":2018,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; National Cancer Institute, Cairo University; Biotechnology and Biological Sciences Research Council; National Cancer Institute; National Institutes of Health; Mary Kay Foundation; American Cancer Society; U.S. Department of Defense; Lustgarten Foundation; American Association for Cancer Research","keywords":"Biology; Autophagy; Phosphatidylinositol; Kinase; Cell biology; Lipid metabolism; Protein-Serine-Threonine Kinases; Metabolism; Biochemistry; Phosphate; Protein kinase A; Apoptosis","score_opus":0.005814138429088461,"score_gpt":0.23641886164038425,"score_spread":0.2306047232112958,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2801628465","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96174663,0.021686438,0.00448881,0.000268915,0.0005515264,0.00056174793,0.000047095175,0.00027553586,0.010373292],"genre_scores_gemma":[0.9868652,0.00015253726,0.002334812,0.0026077842,0.00034368638,0.000039870825,0.0001467094,0.00009522545,0.007414157],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975664,0.00011249591,0.00047119308,0.0006612046,0.000537131,0.000651558],"domain_scores_gemma":[0.9983731,0.000048051395,0.00017342904,0.0008050081,0.00020159259,0.00039882484],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020471754,0.0004163331,0.00053141866,0.00010136883,0.00022153194,0.00005736673,0.00024632196,0.00019256191,0.0011174097],"category_scores_gemma":[0.000051309198,0.00038917313,0.00031187956,0.0003345374,0.0002570841,0.00012162716,0.000083412,0.00022887143,0.00069191976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023362001,0.0003803003,0.000117508665,0.00011577048,0.0001842328,0.00047324374,0.00058187364,0.000008947574,0.98114043,0.00036036846,0.007167167,0.009236544],"study_design_scores_gemma":[0.0020974337,0.00030039728,0.00051762984,0.00005245483,0.00024137052,0.000009727678,0.00008128596,0.00069111574,0.89869446,0.00032295787,0.09663882,0.00035236575],"about_ca_topic_score_codex":0.000068431196,"about_ca_topic_score_gemma":6.212813e-7,"teacher_disagreement_score":0.08947165,"about_ca_system_score_codex":0.00005082836,"about_ca_system_score_gemma":0.00011417533,"threshold_uncertainty_score":0.999856},"labels":[],"label_agreement":null},{"id":"W2802759755","doi":"10.1016/j.chom.2018.04.008","title":"Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria","year":2018,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":134,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; University of Toronto","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Canada; Vertex Pharmaceuticals","keywords":"Biology; Autophagy; Intracellular parasite; Microbiology; Shigella flexneri; Intracellular; Bacteria; Lytic cycle; Listeria monocytogenes; Alternative complement pathway; Proteases; Complement system; Salmonella enterica; Shigella; Bacterial outer membrane; Immune system; Cell biology; Salmonella; Virology; Apoptosis; Immunology; Enzyme; Biochemistry; Escherichia coli","score_opus":0.013396259322055407,"score_gpt":0.2703545536111312,"score_spread":0.2569582942890758,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802759755","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934032,0.0006742744,0.0002527263,0.00013623826,0.000514466,0.0004602524,0.00007302435,0.00007101454,0.0044148345],"genre_scores_gemma":[0.99568,0.00047858112,0.00087811344,0.00049669493,0.00042233226,0.00001397326,0.000109852546,0.000032546275,0.001887946],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987852,0.000049280683,0.000368055,0.0003122283,0.00019944056,0.00028581158],"domain_scores_gemma":[0.99897903,0.000040610597,0.00019366368,0.00045041426,0.00018712106,0.00014915827],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000098301556,0.00019437386,0.00031557112,0.00011775719,0.00010379632,0.000015429492,0.00014188573,0.000092407754,0.0021705127],"category_scores_gemma":[0.000014981201,0.00017576032,0.0001345197,0.00014951288,0.00017488036,0.0000655217,0.000076899625,0.000112283655,0.00033404253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024075895,0.0004105534,0.0019793636,0.00010088249,0.00009151992,0.00003844612,0.00063900085,2.9016633e-7,0.99148285,0.00012698094,0.0043949015,0.0004944348],"study_design_scores_gemma":[0.0019886876,0.0007336268,0.06716213,0.00010453657,0.00012196051,0.000016352808,0.00024298836,0.0000074371765,0.91624457,0.00008794017,0.013146531,0.00014324972],"about_ca_topic_score_codex":0.000073798146,"about_ca_topic_score_gemma":0.000013274644,"teacher_disagreement_score":0.0752383,"about_ca_system_score_codex":0.00009189867,"about_ca_system_score_gemma":0.00016973684,"threshold_uncertainty_score":0.9987416},"labels":[],"label_agreement":null},{"id":"W2803005522","doi":"10.1016/j.celrep.2018.03.098","title":"MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca2+ Stress","year":2018,"lang":"en","type":"article","venue":"Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Heart, Lung, and Blood Institute; Fondo Nacional de Desarrollo Científico, Tecnológico y de Innovación Tecnológica; American Historical Association; National Science Foundation of Sri Lanka; China Scholarship Council; National Center for Research Resources; National Institute of General Medical Sciences; American Heart Association; National Institutes of Health; National Science Foundation","keywords":"Mitophagy; Mitochondrion; Cell biology; Cytosol; Autophagy; Mitochondrial permeability transition pore; Programmed cell death; Biology; C2 domain; Chemistry; Apoptosis; Biochemistry","score_opus":0.011669549267515284,"score_gpt":0.2592339916738324,"score_spread":0.2475644424063171,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2803005522","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967913,0.00016208852,0.0002736174,0.00014276656,0.0004295042,0.00028531026,0.0000028190025,0.0000571464,0.001855419],"genre_scores_gemma":[0.9978542,0.000034942947,0.00020340494,0.00031112466,0.0009586623,0.000015041308,0.00006230346,0.000017852433,0.0005424826],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992269,0.000016072148,0.0002137638,0.0002494099,0.00016057954,0.00013326775],"domain_scores_gemma":[0.99947494,0.000017995593,0.00011020333,0.00022527059,0.0000788077,0.00009277852],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000043151627,0.00010974835,0.00014963179,0.000053898937,0.00007569921,0.000016774642,0.00001786397,0.00008933224,0.00028338193],"category_scores_gemma":[0.000021910662,0.000095277515,0.000050331306,0.000060345774,0.000056554043,0.000100508165,0.000007330503,0.000060220864,0.0000075427165],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006067199,0.00031357235,0.003599886,0.0001740818,0.000051100382,0.0011667284,0.0014450602,0.0000014670617,0.97153753,0.000005965256,0.0017296331,0.019368272],"study_design_scores_gemma":[0.0009799342,0.0003335491,0.024748879,0.000120168756,0.00010310293,0.0002775525,0.00007970877,0.00044256973,0.9679012,0.00024877637,0.0046208994,0.00014368635],"about_ca_topic_score_codex":0.000024460769,"about_ca_topic_score_gemma":0.0000063296206,"teacher_disagreement_score":0.021148993,"about_ca_system_score_codex":0.00001911218,"about_ca_system_score_gemma":0.00005096232,"threshold_uncertainty_score":0.38853043},"labels":[],"label_agreement":null},{"id":"W2804637321","doi":"10.1155/2018/6463807","title":"Geranylgeraniol Prevents Statin‐Dependent Myotoxicity in C2C12 Muscle Cells through RAP1 GTPase Prenylation and Cytoprotective Autophagy","year":2018,"lang":"en","type":"article","venue":"Oxidative Medicine and Cellular Longevity","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministerstwo Edukacji i Nauki; School of Medicine, New York University; Narodowe Centrum Nauki; York University","keywords":"Geranylgeraniol; Viability assay; Statin; Mevalonate pathway; Myogenesis; Chemistry; Fluvastatin; Pharmacology; Atorvastatin; Mevalonic acid; Myocyte; Biology; Cell biology; Biochemistry; Farnesol; Simvastatin; Apoptosis","score_opus":0.02486738415984791,"score_gpt":0.29664392268914186,"score_spread":0.27177653852929395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2804637321","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9872899,0.0024267454,0.0067168144,0.00033405554,0.00015717081,0.0015617171,0.00002660631,0.00005770312,0.0014292661],"genre_scores_gemma":[0.99715334,0.0006166136,0.00057161006,0.00071616605,0.0004054851,0.00008326364,0.000049111626,0.000033497312,0.000370923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976318,0.00033706677,0.00047909614,0.00070141506,0.00045390963,0.00039673367],"domain_scores_gemma":[0.99883884,0.00014835429,0.00021579654,0.00038322376,0.00015358318,0.00026018222],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00067073386,0.00036955968,0.0006599268,0.0001550296,0.00019483511,0.000018862376,0.00009197642,0.0001717197,0.00066628173],"category_scores_gemma":[0.0001311401,0.00029427427,0.00006412342,0.00030091315,0.0005483939,0.00030739728,0.00008359156,0.0003808814,0.000019848201],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010493434,0.0007520911,0.0054922327,0.00034279923,0.00021738072,0.00030074763,0.015277024,0.0000019795523,0.9495816,0.00027743436,0.0001842048,0.026523152],"study_design_scores_gemma":[0.008498213,0.002232083,0.15267506,0.0005521689,0.00024374393,0.000020498266,0.0012655536,0.0008471819,0.82870734,0.0035812154,0.00095638644,0.000420567],"about_ca_topic_score_codex":0.0004903223,"about_ca_topic_score_gemma":0.000057946578,"teacher_disagreement_score":0.14718282,"about_ca_system_score_codex":0.00009599455,"about_ca_system_score_gemma":0.00008303378,"threshold_uncertainty_score":0.99995095},"labels":[],"label_agreement":null},{"id":"W2806482429","doi":"10.20944/preprints201805.0413.v1","title":"A Current Overview of the Molecular Effects of Nanosilver","year":2018,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Endoplasmic reticulum; Autophagy; Unfolded protein response; Cell biology; Oxidative stress; Reactive oxygen species; Chemistry; DNA damage; Function (biology); Carcinogenesis; Nanotechnology; Apoptosis; Biology; Materials science; Biochemistry; DNA","score_opus":0.09434354839170858,"score_gpt":0.3908944271148753,"score_spread":0.29655087872316677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806482429","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97826445,0.017851247,0.000043297958,0.00011680056,0.0011069888,0.0013869462,0.000017344446,0.000039367493,0.0011735691],"genre_scores_gemma":[0.9970298,0.0023010422,0.000032516036,0.00020746952,0.00012496067,0.0001137715,0.0000119576425,0.000039744747,0.00013878105],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980063,0.000185685,0.0005196226,0.0005302987,0.00054113154,0.0002169655],"domain_scores_gemma":[0.9968884,0.00006236639,0.0005199643,0.0021735479,0.00024122039,0.00011451477],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027105844,0.00029878074,0.00070931774,0.00008309466,0.000027832688,0.000002338188,0.00056750036,0.00023489796,0.0005818108],"category_scores_gemma":[0.00026951535,0.00021310344,0.00070406805,0.0001558416,0.00025801043,0.00001942807,0.001443476,0.00052167353,0.00014407809],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036036497,0.0019087775,0.6655002,0.019188505,0.0016927691,0.000043090742,0.0012898939,0.000027111311,0.30460587,0.001771166,0.00026905705,0.003343183],"study_design_scores_gemma":[0.0005738628,0.000033529974,0.41214126,0.0031003642,0.00039173404,0.0000026711261,0.0000028839702,0.000010960326,0.5801502,0.002085814,0.0013973837,0.00010931549],"about_ca_topic_score_codex":0.00004365537,"about_ca_topic_score_gemma":4.4584456e-7,"teacher_disagreement_score":0.27554435,"about_ca_system_score_codex":0.000061880564,"about_ca_system_score_gemma":0.0003569653,"threshold_uncertainty_score":0.8690106},"labels":[],"label_agreement":null},{"id":"W2806723183","doi":"10.1016/j.celrep.2018.07.017","title":"Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation","year":2018,"lang":"en","type":"article","venue":"Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"Medical Research Council; Hjärnfonden; Lunds Universitet; Vetenskapsrådet; University of Cambridge; Stiftelsen för Strategisk Forskning; National Institute for Health and Care Research","keywords":"Argonaute; Autophagy; Huntingtin; Cell biology; microRNA; Chemistry; Biology; RNA interference; Apoptosis; Gene; RNA; Biochemistry","score_opus":0.01809307063101474,"score_gpt":0.31155331710797995,"score_spread":0.2934602464769652,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806723183","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908979,0.00029600094,0.0015731199,0.00021878208,0.0003625247,0.0004409773,0.0000018798388,0.00013990582,0.0060689244],"genre_scores_gemma":[0.9965677,0.000008357342,0.0014735131,0.0004936648,0.00047208622,0.000010132962,0.000049454782,0.000019725725,0.0009053274],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987974,0.000021469621,0.00036307468,0.00037187795,0.00022236821,0.0002237846],"domain_scores_gemma":[0.9991091,0.000017771014,0.00022573568,0.00030450535,0.00014722427,0.00019567984],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024010711,0.00014932208,0.00019452283,0.000078813915,0.00013936458,0.00004404047,0.000029908679,0.000102884005,0.00011732797],"category_scores_gemma":[0.00009231951,0.00014575403,0.000059808975,0.0002410138,0.00005944142,0.00014812472,0.000033915527,0.000058066194,0.00006319171],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00063872465,0.00042371656,0.4054531,0.00027838626,0.00015019845,0.00096573954,0.0021213212,0.00020712928,0.4281247,0.0005047848,0.0068878247,0.15424441],"study_design_scores_gemma":[0.0007439622,0.00028551114,0.65980524,0.00014727861,0.00010457658,0.00041767856,0.00005453064,0.0015870493,0.3281119,0.001725702,0.006777763,0.00023883022],"about_ca_topic_score_codex":0.000033331587,"about_ca_topic_score_gemma":0.000007167637,"teacher_disagreement_score":0.25435215,"about_ca_system_score_codex":0.00011889731,"about_ca_system_score_gemma":0.00008420794,"threshold_uncertainty_score":0.59436774},"labels":[],"label_agreement":null},{"id":"W2806773654","doi":"10.1016/j.atherosclerosissup.2018.04.048","title":"Maternal Exercise Improves Glucose Homeostasis and Vascular Health in Male Offspring","year":2018,"lang":"en","type":"article","venue":"Atherosclerosis Supplements","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"Autophagy; Homeostasis; Biology; Cell biology; Flux (metallurgy); Mitochondrion; Glucose homeostasis; Glycolysis; Metabolism; Chemistry; Biochemistry; Endocrinology; Apoptosis; Insulin","score_opus":0.016790729735407916,"score_gpt":0.2861392715814937,"score_spread":0.2693485418460858,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806773654","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99546903,0.0032036295,0.000039350394,0.0004096278,0.00011584359,0.0006065796,0.000058808135,0.000044625616,0.000052485717],"genre_scores_gemma":[0.9866384,0.010868498,0.0009315365,0.0011959119,0.00010561728,0.0000651726,0.00003545922,0.000043589123,0.0001157712],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99849284,0.00003892732,0.00035989328,0.0003789943,0.0002488925,0.00048047176],"domain_scores_gemma":[0.9992478,0.000010811107,0.00009444862,0.00036797096,0.00003840808,0.00024055057],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002546107,0.0002063248,0.00037454997,0.00012611973,0.00012556222,0.000039521434,0.00011038187,0.00005999935,0.001039316],"category_scores_gemma":[0.0000075156677,0.00018792013,0.00008137032,0.00016306572,0.000103236314,0.00013302713,0.000096050266,0.000102051126,0.00007072176],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035369134,0.00083523255,0.70897424,0.00026538086,0.00026143595,0.000012181398,0.0021627923,3.0291147e-7,0.0782587,0.00007238259,0.0017716646,0.20703197],"study_design_scores_gemma":[0.0044746916,0.0004944508,0.9250002,0.00041518922,0.000049893006,0.0000052689675,0.0001838072,0.000073266434,0.0639241,0.0000911405,0.005101283,0.00018671145],"about_ca_topic_score_codex":0.0008445973,"about_ca_topic_score_gemma":0.00009206635,"teacher_disagreement_score":0.21602593,"about_ca_system_score_codex":0.00009268164,"about_ca_system_score_gemma":0.00005798147,"threshold_uncertainty_score":0.9998739},"labels":[],"label_agreement":null},{"id":"W2806912873","doi":"10.1101/334466","title":"BDNF controls cognitive processes related to neuropsychiatric manifestations via autophagic regulation of p62 and GABA <sub>A</sub> receptor trafficking","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; Campbell Family Mental Health Research Institute; National Institutes of Health; National Alliance for Research on Schizophrenia and Depression; U.S. Department of Defense","keywords":"GABAergic; Prefrontal cortex; Autophagy; Downregulation and upregulation; Cognition; Tropomyosin receptor kinase B; gamma-Aminobutyric acid; Neuroplasticity; Brain-derived neurotrophic factor","score_opus":0.008918358252447476,"score_gpt":0.23557697609965905,"score_spread":0.22665861784721159,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806912873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992454,0.0020949075,0.0014481941,0.00028386826,0.000800012,0.002197337,0.0003149981,0.00038953434,0.000017140721],"genre_scores_gemma":[0.9970276,0.00057986664,0.0011633801,0.00037967367,0.000449023,0.00023087813,0.000005438556,0.00015849876,0.0000056470662],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99709934,0.00016617507,0.0008428187,0.0009932179,0.0004649602,0.00043347254],"domain_scores_gemma":[0.99655676,0.00018469992,0.000714813,0.00063082407,0.0015047258,0.0004082046],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003709122,0.0005523449,0.00079469295,0.00057025615,0.00018201664,0.0000759442,0.00018757799,0.00046517246,0.000060457565],"category_scores_gemma":[0.0005658625,0.0005803991,0.00014562786,0.0010249708,0.00020713809,0.00015806721,0.00012656578,0.00050539913,0.00006602619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005641566,0.0004837453,0.004188672,0.0016506129,0.00055834674,0.00006330584,0.00013618953,0.000042107604,0.9919063,0.00014344968,0.00021209447,0.00005100592],"study_design_scores_gemma":[0.0027416584,0.00054934993,0.48262513,0.0017423431,0.0010342282,4.7535846e-7,0.000012714638,0.00058447995,0.50984025,0.000020473188,0.00016642036,0.00068246946],"about_ca_topic_score_codex":0.0000062596137,"about_ca_topic_score_gemma":0.0000013918051,"teacher_disagreement_score":0.48206607,"about_ca_system_score_codex":0.00011341636,"about_ca_system_score_gemma":0.00088541815,"threshold_uncertainty_score":0.9996647},"labels":[],"label_agreement":null},{"id":"W2806967170","doi":"10.1093/hmg/ddy219","title":"Ulk2 controls cortical excitatory–inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons","year":2018,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Center for Research Resources; National Institute of Mental Health; Japan Society for the Promotion of Science; Maryland Stem Cell Research Fund; Takeda Science Foundation; National Alliance for Research on Schizophrenia and Depression; Stanley Foundation; Takeda Pharmaceutical Company; Naito Foundation; U.S. Department of Defense","keywords":"GABAA receptor; Biology; Neuroscience; Pyramidal cell; Inhibitory postsynaptic potential; gamma-Aminobutyric acid; Autophagy; Excitatory postsynaptic potential; Neurotransmission; Cell biology; Receptor; Hippocampus; Biochemistry","score_opus":0.010985223617782106,"score_gpt":0.2727306802236721,"score_spread":0.26174545660589,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806967170","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99553037,0.0018762989,0.0016904054,0.00005301929,0.00014227016,0.00037066548,0.000004693494,0.00003961468,0.00029263925],"genre_scores_gemma":[0.9984941,0.00004116165,0.00067473185,0.0004442165,0.0002354649,0.0000107108435,0.000017726386,0.00003736978,0.000044535744],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99872607,0.00010356371,0.00036974158,0.00029607967,0.0002607094,0.00024382518],"domain_scores_gemma":[0.99931234,0.00003132408,0.00010580543,0.00031408618,0.00009562318,0.0001407994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012862518,0.00016480758,0.00030513923,0.00010858406,0.000066728455,0.000012552427,0.000072592156,0.00011865773,0.00011074356],"category_scores_gemma":[0.000036123332,0.00017265664,0.00007374077,0.00011655766,0.0003920084,0.000026845866,0.000027892582,0.00016234338,0.0000105700665],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013620719,0.00017306414,0.0069318274,0.000046814323,0.00004145577,0.000050860945,0.00037630112,0.000039319268,0.9897725,0.00066097395,0.00007049502,0.0017001885],"study_design_scores_gemma":[0.0032847307,0.0008217431,0.83223563,0.00011563963,0.00009724927,0.000021412485,0.000037682636,0.006590148,0.1552147,0.00096542464,0.00040013713,0.00021549949],"about_ca_topic_score_codex":0.0000040030814,"about_ca_topic_score_gemma":0.0000037521638,"teacher_disagreement_score":0.8345578,"about_ca_system_score_codex":0.000032773678,"about_ca_system_score_gemma":0.00005911137,"threshold_uncertainty_score":0.70407337},"labels":[],"label_agreement":null},{"id":"W2807114871","doi":"10.1152/ajpendo.00391.2017","title":"Parkin is required for exercise-induced mitophagy in muscle: impact of aging","year":2018,"lang":"en","type":"article","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":107,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Canada","keywords":"Parkin; Mitophagy; Ubiquitin; Mitochondrial biogenesis; Mitochondrion; Ubiquitin ligase; Cell biology; Biology; Endocrinology; Internal medicine; Autophagy; Medicine; Biochemistry; Parkinson's disease; Apoptosis","score_opus":0.01829031987703207,"score_gpt":0.3312811655804532,"score_spread":0.3129908457034211,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2807114871","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99418986,0.004874741,0.000030709973,0.00032401193,0.00031553573,0.0001963121,0.000013712207,0.000009698462,0.000045416302],"genre_scores_gemma":[0.9960769,0.0020609593,0.00068734266,0.00057688367,0.0005419868,0.0000110061765,0.0000024242202,0.000020456686,0.000022049751],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985319,0.00012761452,0.0005668556,0.00023702013,0.00009942829,0.00043719774],"domain_scores_gemma":[0.99858016,0.00013805013,0.00061968993,0.00024281432,0.00026175,0.0001575352],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016414233,0.00020320559,0.0011454984,0.00035805017,0.000057594498,0.0000031073978,0.00015297551,0.00007067056,0.00009078174],"category_scores_gemma":[0.00007511349,0.00015081793,0.00033478483,0.0002583663,0.00079847436,0.00010718931,0.000036971993,0.0002571078,0.0000024799663],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022667455,0.0002857942,0.0036847158,0.00003570106,0.00067628676,0.000034215114,0.0012029371,0.0000014635375,0.8546973,0.0001859633,0.00032520603,0.13660367],"study_design_scores_gemma":[0.0047334614,0.0027528666,0.8672187,0.0001095463,0.00034098266,0.0001883149,0.00045145393,0.000027258277,0.12046019,0.0026184928,0.00094796997,0.00015081924],"about_ca_topic_score_codex":0.00010224691,"about_ca_topic_score_gemma":0.0000017080991,"teacher_disagreement_score":0.8635339,"about_ca_system_score_codex":0.00002280631,"about_ca_system_score_gemma":0.00019733164,"threshold_uncertainty_score":0.61501765},"labels":[],"label_agreement":null},{"id":"W2807425977","doi":"10.1186/s13045-018-0618-0","title":"miR-519a enhances chemosensitivity and promotes autophagy in glioblastoma by targeting STAT3/Bcl2 signaling pathway","year":2018,"lang":"en","type":"article","venue":"Journal of Hematology & Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":224,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"Glioblastoma; Autophagy; Cancer research; Hematology; Signal transduction; Temozolomide; Medicine; Pathway analysis; STAT3; Oncology; Chemistry; Internal medicine; Apoptosis; Gene; Gene expression; Biochemistry","score_opus":0.00963251872505067,"score_gpt":0.30180095130822965,"score_spread":0.292168432583179,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2807425977","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923223,0.0048012636,0.00025285047,0.0017564519,0.0003319936,0.0002000602,0.0000044992303,0.00002410989,0.000306473],"genre_scores_gemma":[0.99647033,0.00011907179,0.0020078586,0.0009957242,0.0003229081,0.000005706728,0.0000022791933,0.000023214674,0.000052897645],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99798,0.0003030732,0.00081687036,0.0002639617,0.00020072088,0.00043535573],"domain_scores_gemma":[0.9982144,0.0005092607,0.0006589611,0.0001292477,0.00027298488,0.00021512757],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009485811,0.00021597563,0.0010673903,0.00023306234,0.00009804065,0.000010576791,0.00010702162,0.00031225008,0.00018492433],"category_scores_gemma":[0.00036450333,0.0001750964,0.000116390984,0.00016394525,0.00049741333,0.00015254479,0.000050023544,0.00050388125,0.00001400745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023195392,0.001044049,0.0054718787,0.00013053614,0.00029032014,0.004524336,0.0020353214,7.336215e-7,0.9730843,0.00037610866,0.0025777742,0.00814511],"study_design_scores_gemma":[0.0034794877,0.0049918084,0.0015117183,0.00018701497,0.00008442093,0.0065725786,0.00052336726,0.000114227274,0.9753366,0.0014583399,0.0055792993,0.00016115289],"about_ca_topic_score_codex":0.000010839996,"about_ca_topic_score_gemma":0.000022706421,"teacher_disagreement_score":0.007983957,"about_ca_system_score_codex":0.000115326584,"about_ca_system_score_gemma":0.00044318743,"threshold_uncertainty_score":0.7140224},"labels":[],"label_agreement":null},{"id":"W2808097850","doi":"10.15252/embj.2018100014","title":"Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation","year":2018,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Medical Research Council; Canadian Institutes of Health Research; Boehringer Ingelheim Fonds; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Wellcome Trust","keywords":"Biology; Parkin; Phosphorylation; Cell biology","score_opus":0.03934721523997077,"score_gpt":0.31761879406834453,"score_spread":0.2782715788283738,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2808097850","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952617,0.0008855646,0.0005300421,0.0010451191,0.00019074275,0.0002531677,0.0000018756369,0.000013649736,0.001818116],"genre_scores_gemma":[0.99829763,0.00033732073,0.00017799468,0.0004095731,0.00039606768,0.000006709973,0.0000025219506,0.0000127667845,0.00035943752],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99920315,0.00008904095,0.0002419155,0.00008932812,0.00022617949,0.00015040307],"domain_scores_gemma":[0.9993529,0.00007652801,0.00018655696,0.0001691378,0.00009984079,0.00011505028],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047180048,0.00009468066,0.00018370312,0.00005847942,0.00016465927,0.00001702,0.000076677396,0.000040158233,0.0004180508],"category_scores_gemma":[0.000055117474,0.000055820907,0.00006310241,0.000124298,0.000182956,0.00005245968,0.000014511875,0.00017700548,0.000011851196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.014382872,0.0013759985,0.0049459473,0.00016225505,0.0036404938,0.00035640632,0.014837881,0.000025772031,0.7074457,0.009786354,0.021673208,0.22136715],"study_design_scores_gemma":[0.013758343,0.0035551086,0.09922229,0.0010685805,0.0009740899,0.00097311276,0.0021056815,0.0007104141,0.791404,0.0459492,0.03981965,0.00045953513],"about_ca_topic_score_codex":0.000009308458,"about_ca_topic_score_gemma":5.5644534e-7,"teacher_disagreement_score":0.22090761,"about_ca_system_score_codex":0.000053654345,"about_ca_system_score_gemma":0.00009520857,"threshold_uncertainty_score":0.4577363},"labels":[],"label_agreement":null},{"id":"W2809299334","doi":"10.1016/j.bbrc.2018.06.056","title":"Control of autophagosome size and number by Atg7","year":2018,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Manitoba; National Sleep Foundation; The Ministry of Economic Affairs and Employment; National Science Foundation","keywords":"ATG8; Autophagosome; Autophagy; Cell biology; Limiting; Chemistry; Phagosome; Biology; Apoptosis; Biochemistry; Intracellular; Engineering","score_opus":0.04219896986017776,"score_gpt":0.3981655049928066,"score_spread":0.3559665351326289,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2809299334","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901954,0.0016839516,0.00002389731,0.0054987585,0.0000070854376,0.00023401715,0.000062163024,0.000024297102,0.0022704601],"genre_scores_gemma":[0.997872,0.0009096218,0.00046495645,0.00027500236,0.00009496696,0.000031271935,0.00002023242,0.000009301887,0.00032265874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990504,0.000105616455,0.00016436193,0.00018380037,0.00028069975,0.0002151439],"domain_scores_gemma":[0.9980135,0.00073490245,0.00002861221,0.0006750292,0.00028783522,0.0002601123],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020635073,0.00008479093,0.0002054545,0.000024534773,0.0001669893,0.000015527788,0.00022932053,0.0000866345,0.00013451699],"category_scores_gemma":[0.00036706834,0.00006455906,0.000048815473,0.00022972179,0.0025711225,0.000036415728,0.00019899536,0.0002634455,0.00003776703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018438941,0.0005335548,0.00057406235,0.00003409513,0.000057301637,7.32186e-7,0.000052737745,3.2817724e-10,0.9871369,0.0061597247,0.0029960847,0.0022704273],"study_design_scores_gemma":[0.0034181732,0.000921508,0.036380257,0.00015381098,0.00009591318,0.000016763186,0.00009327628,0.0007049552,0.9247559,0.008102865,0.02513664,0.00021999527],"about_ca_topic_score_codex":0.00004666297,"about_ca_topic_score_gemma":3.629544e-7,"teacher_disagreement_score":0.062381048,"about_ca_system_score_codex":0.00001554962,"about_ca_system_score_gemma":0.00005853711,"threshold_uncertainty_score":0.9473408},"labels":[],"label_agreement":null},{"id":"W2810603360","doi":"10.1080/15548627.2018.1461294","title":"Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease","year":2018,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":152,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Biology; Mitophagy; Disease; Lewy body; Autophagy; Ubiquitin; Parkin; Alpha-synuclein; Neuroscience; Parkinson's disease; Pathology; Genetics; Medicine","score_opus":0.007390071700400423,"score_gpt":0.25376398801347816,"score_spread":0.24637391631307773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2810603360","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99104726,0.0064042485,0.000017698667,0.0007459613,0.00020496684,0.000538045,0.000049286005,0.000053285214,0.000939217],"genre_scores_gemma":[0.99576086,0.00024757028,0.00005933462,0.0019371737,0.00025021506,0.000041991287,0.000014259898,0.000042600743,0.001646004],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9982238,0.00013811114,0.00039617548,0.000454909,0.00038297623,0.000404035],"domain_scores_gemma":[0.9984095,0.00010268964,0.00013154259,0.0005919253,0.00007081278,0.0006935469],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027008983,0.00027030281,0.00037230417,0.00012563464,0.00014068547,0.00003236603,0.00017221653,0.000075738826,0.0003769731],"category_scores_gemma":[0.00019755927,0.0002042885,0.0001161657,0.00022053141,0.0005627002,0.00015556937,0.00024234968,0.00020494369,0.000014193287],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005828264,0.0014413714,0.94275486,0.0009059968,0.00035903603,0.0048634117,0.0016095534,0.0000039967576,0.017441632,0.0031454766,0.0017055827,0.019940784],"study_design_scores_gemma":[0.0030198959,0.00011622064,0.97999334,0.00027501225,0.00018503674,0.000032432272,0.00007103271,0.00069331325,0.012748028,0.001611773,0.0010438281,0.00021008632],"about_ca_topic_score_codex":0.00026709144,"about_ca_topic_score_gemma":0.000030491428,"teacher_disagreement_score":0.037238445,"about_ca_system_score_codex":0.00004781451,"about_ca_system_score_gemma":0.00026856348,"threshold_uncertainty_score":0.8330643},"labels":[],"label_agreement":null},{"id":"W2810958997","doi":"10.1113/jp275604","title":"Protective role of Parkin in skeletal muscle contractile and mitochondrial function","year":2018,"lang":"en","type":"article","venue":"The Journal of Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; McGill University Health Centre; Université de Montréal; Quebec Rehabilitation Research Network; Institut Universitaire de Gériatrie de Montréal; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Parkin; Mitophagy; Ubiquitin ligase; Skeletal muscle; Mitochondrion; Biology; Cell biology; MFN2; Ubiquitin; Endocrinology; Internal medicine; mitochondrial fusion; Biochemistry; Mitochondrial DNA; Parkinson's disease; Medicine; Gene","score_opus":0.007080368618727781,"score_gpt":0.2558883315631604,"score_spread":0.24880796294443258,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2810958997","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99874896,0.0006090325,0.00006625966,0.00013389585,0.00016917314,0.00014822092,0.0000011830734,0.0000020923849,0.000121193196],"genre_scores_gemma":[0.99911386,0.00004339022,0.000021482154,0.00010990153,0.00069322286,0.0000021687729,3.936689e-7,0.0000046858227,0.000010873076],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99950004,0.00011776037,0.00018401581,0.000047044872,0.00006931326,0.00008181104],"domain_scores_gemma":[0.9995215,0.00006924708,0.0002015025,0.000079333666,0.00009792709,0.000030516729],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013925086,0.00005098255,0.00019908744,0.00004760087,0.0000236297,9.915512e-7,0.000042980002,0.000045025783,0.00010981335],"category_scores_gemma":[0.000045917754,0.00002983651,0.000044279415,0.000052544612,0.00017459098,0.00004597799,0.000010932658,0.00015684227,0.0000030684548],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026024338,0.00012269572,0.00006933891,0.0000071252757,0.00008556886,0.0000019187098,0.00053269713,0.0000030749559,0.99122304,0.000056646662,0.000076359305,0.005219087],"study_design_scores_gemma":[0.003706433,0.004295902,0.8286368,0.00006641759,0.00016582952,0.00008787202,0.00070693565,0.00013317073,0.139339,0.02080918,0.0019950005,0.00005744261],"about_ca_topic_score_codex":0.000030415218,"about_ca_topic_score_gemma":0.000008042369,"teacher_disagreement_score":0.85188407,"about_ca_system_score_codex":0.000011968295,"about_ca_system_score_gemma":0.00004865182,"threshold_uncertainty_score":0.121669754},"labels":[],"label_agreement":null},{"id":"W2813127697","doi":"10.1038/s41467-018-04849-7","title":"A TFEB nuclear export signal integrates amino acid supply and glucose availability","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":122,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Medical Research Council; China Scholarship Council; National Cancer Institute; National Institutes of Health; Cancer Research UK; Wellcome Trust; RIKEN; Karolinska Institutet; Kennedy Trust for Rheumatology Research; Ludwig Institute for Cancer Research","keywords":"TFEB; Phosphorylation; mTORC1; Cell biology; Nuclear export signal; Nuclear transport; Lysosome; Autophagy; Nuclear localization sequence; Biology; Transcription factor; Biochemistry; Chemistry; Protein kinase B; Cell nucleus; Cytoplasm; Gene","score_opus":0.017610535204294547,"score_gpt":0.30768525368488403,"score_spread":0.29007471848058947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2813127697","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9677868,0.016821578,0.0000173816,0.0054714927,0.000076371856,0.00035611854,0.000041688185,0.00015799583,0.00927058],"genre_scores_gemma":[0.9911582,0.0012654542,0.0045519527,0.0025311313,0.00011677779,0.000023645282,0.00010705112,0.000021226373,0.00022455685],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992224,0.000082189654,0.00019486855,0.00020128912,0.000145163,0.00015411056],"domain_scores_gemma":[0.99779904,0.00011201582,0.000062394975,0.0016342842,0.00024209428,0.00015018502],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018993106,0.00013025844,0.00018692944,0.000064370455,0.0002909424,0.000027186032,0.0004036101,0.00023168254,0.0007584354],"category_scores_gemma":[0.0001352745,0.00010710597,0.0000698679,0.00019069893,0.00063946156,0.00009687981,0.00019390389,0.00071948295,0.00012792843],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016844751,0.005097827,0.26397094,0.00017062046,0.0010998204,0.0000504704,0.0110254595,6.347371e-8,0.41243428,0.074657194,0.10611267,0.12369617],"study_design_scores_gemma":[0.00188434,0.00070033554,0.4828043,0.0001464517,0.0002599902,0.000104274135,0.00095840567,0.00050977425,0.061819725,0.0026181303,0.44783372,0.00036056648],"about_ca_topic_score_codex":0.000016195962,"about_ca_topic_score_gemma":0.000057268422,"teacher_disagreement_score":0.35061455,"about_ca_system_score_codex":0.000042921547,"about_ca_system_score_gemma":0.0000902776,"threshold_uncertainty_score":0.8304336},"labels":[],"label_agreement":null},{"id":"W2884593370","doi":"10.1158/1541-7786.mcr-18-0024","title":"Autophagy Governs Protumorigenic Effects of Mitotic Slippage–induced Senescence","year":2018,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Windsor Clinical Research","funders":"Nanyang Technological University; Ministry of Education - Singapore; National Research Foundation Singapore; National Research Foundation","keywords":"Autophagy; ATG5; Senescence; Cell biology; Biology; Cancer research; Mitosis; Mitotic catastrophe; Paracrine signalling; Programmed cell death; Apoptosis; Genetics","score_opus":0.040052766513746965,"score_gpt":0.4118277138129465,"score_spread":0.3717749472991996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2884593370","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99313784,0.002772967,0.0004628507,0.0003843572,0.00025959584,0.0014032124,0.0000053493754,0.000050476156,0.0015233415],"genre_scores_gemma":[0.997771,0.00014366521,0.00014367395,0.000255704,0.00036754986,0.0003125441,0.0000037736336,0.000048769012,0.00095331407],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99735826,0.00024010941,0.00023595388,0.00042217597,0.0011466971,0.0005968101],"domain_scores_gemma":[0.9983766,0.00008847156,0.000062408224,0.0006945837,0.0005125694,0.00026538002],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039025274,0.00016590861,0.00031773926,0.00018482926,0.00011979905,0.000018642066,0.00027467168,0.00010850825,0.00043120372],"category_scores_gemma":[0.00023277337,0.00014399867,0.00014588334,0.0007351154,0.00033086585,0.00005091741,0.00011065581,0.00036765594,0.00012826077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037495382,0.00024011795,0.00064826483,0.000586077,0.00017497138,0.0006311136,0.00026772096,8.4664026e-7,0.98774546,0.0006435862,0.0002853869,0.008401523],"study_design_scores_gemma":[0.0011708469,0.0011276555,0.01742027,0.00039655305,0.000054623637,0.000015365997,0.000028740615,0.0001828521,0.97835255,0.00048030177,0.0006439613,0.00012625447],"about_ca_topic_score_codex":0.0004141541,"about_ca_topic_score_gemma":0.00001388776,"teacher_disagreement_score":0.016772006,"about_ca_system_score_codex":0.0002177494,"about_ca_system_score_gemma":0.00075845816,"threshold_uncertainty_score":0.5872095},"labels":[],"label_agreement":null},{"id":"W2885138233","doi":"10.1016/j.jtcvs.2018.07.047","title":"A novel role of endothelial autophagy as a regulator of myocardial fatty acid oxidation","year":2018,"lang":"en","type":"article","venue":"Journal of Thoracic and Cardiovascular Surgery","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital; University of Alberta","funders":"Heart and Stroke Foundation of Canada","keywords":"Autophagy; Umbilical vein; Beta oxidation; Small interfering RNA; Internal medicine; Fatty acid; Endocrinology; Medicine; Endothelial stem cell; Fatty acid metabolism; Metabolism; Biology; Biochemistry; RNA; Apoptosis; Gene","score_opus":0.013141049147269311,"score_gpt":0.27384495797461905,"score_spread":0.26070390882734973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2885138233","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9748529,0.019726107,0.004486345,0.000033818473,0.0003816355,0.00012622404,0.000015562015,0.000009644446,0.0003677725],"genre_scores_gemma":[0.99681026,0.0011202018,0.00090702804,0.000069781134,0.0010386442,0.0000024231567,0.000003488934,0.000022778117,0.000025422645],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981326,0.00013122878,0.00066483655,0.00015877438,0.00073903415,0.00017353777],"domain_scores_gemma":[0.9983765,0.00008848851,0.000455468,0.00037739283,0.00052890304,0.00017326737],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015140405,0.00015584589,0.0010795133,0.0002580096,0.000044749973,0.000009706378,0.00007965368,0.00012918448,0.00006697426],"category_scores_gemma":[0.00023393094,0.00012462684,0.0017642471,0.00020642413,0.00020796029,0.00015707135,0.00002988633,0.00013905285,0.0000037244383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003702081,0.00037509232,0.0069854343,0.0002872762,0.008800084,0.00014309373,0.0006102683,0.000013526663,0.6803268,0.00013235054,0.00021871876,0.29840523],"study_design_scores_gemma":[0.0010510123,0.0003771354,0.062183365,0.0003483581,0.0016696617,0.0014239843,0.0002302133,0.000041009884,0.92858845,0.00037588057,0.003571636,0.00013928684],"about_ca_topic_score_codex":0.000023113093,"about_ca_topic_score_gemma":2.130632e-7,"teacher_disagreement_score":0.29826593,"about_ca_system_score_codex":0.000023555005,"about_ca_system_score_gemma":0.0003427992,"threshold_uncertainty_score":0.5082135},"labels":[],"label_agreement":null},{"id":"W2885251054","doi":"10.1080/15548627.2018.1447290","title":"Importance of TFEB acetylation in control of its transcriptional activity and lysosomal function in response to histone deacetylase inhibitors","year":2018,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Medical Research Council","keywords":"TFEB; Acetylation; Biology; Autophagy; Histone deacetylase; mTORC1; Cell biology; HDAC4; Histone; Transcriptional regulation; Biochemistry; PI3K/AKT/mTOR pathway; Cancer research; Transcription factor; Signal transduction; Apoptosis","score_opus":0.011858364129778755,"score_gpt":0.284626801359642,"score_spread":0.27276843722986327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2885251054","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975849,0.0008500271,0.0003841676,0.00051082246,0.00012434115,0.0004442459,0.000020468222,0.000016514208,0.00006454422],"genre_scores_gemma":[0.999358,0.000020827063,0.00007461978,0.00030295088,0.00007930164,0.000025443089,0.00000485507,0.000012485324,0.000121524514],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989591,0.00011300797,0.00034714487,0.00022031133,0.00020777817,0.00015266243],"domain_scores_gemma":[0.99943393,0.00008867624,0.00011741987,0.00015804461,0.000115216,0.00008670257],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040587824,0.00011245723,0.00031007256,0.00026823295,0.0000197218,0.0000021581143,0.000036024827,0.00009051112,0.000103367674],"category_scores_gemma":[0.00015285451,0.000112452944,0.000052368265,0.00028311065,0.00009666271,0.0001392857,0.00000855162,0.00009817636,0.0000049683313],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018153675,0.00034598584,0.017637279,0.000057989542,0.000028462675,0.00001712364,0.00064619706,0.000019349842,0.95806897,0.00025460898,0.000021194795,0.0047491384],"study_design_scores_gemma":[0.00408948,0.0007674995,0.7441209,0.000081264465,0.00002506966,0.000005198482,0.000027115399,0.0006241337,0.25002462,0.00007693903,0.00009349662,0.0000642507],"about_ca_topic_score_codex":0.0000799442,"about_ca_topic_score_gemma":0.00013413001,"teacher_disagreement_score":0.72648364,"about_ca_system_score_codex":0.00009775877,"about_ca_system_score_gemma":0.0001452709,"threshold_uncertainty_score":0.4585698},"labels":[],"label_agreement":null},{"id":"W2885253203","doi":"10.1080/15548627.2018.1505154","title":"MFN2 retrotranslocation boosts mitophagy by uncoupling mitochondria from the ER","year":2018,"lang":"en","type":"letter","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Biology; MFN2; Mitochondrion; Cell biology; Autophagy; Uncoupling protein; PINK1; mitochondrial fusion; Genetics; Biochemistry; Mitochondrial DNA; Apoptosis; Gene; Brown adipose tissue","score_opus":0.013789515601331846,"score_gpt":0.26140729488384434,"score_spread":0.2476177792825125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2885253203","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11544873,0.048863847,0.0018777681,0.8147379,0.008876541,0.003847099,0.0011337034,0.0010856896,0.004128695],"genre_scores_gemma":[0.028010845,0.00073646166,0.00051527086,0.9075367,0.032556206,0.00029915807,0.006959538,0.0003589475,0.023026874],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99605215,0.00017598692,0.00076730055,0.0011215258,0.0010551299,0.0008279183],"domain_scores_gemma":[0.9970206,0.00047107847,0.00039364237,0.0016575679,0.00026246242,0.00019464607],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00020159232,0.00079076114,0.0009154274,0.00012117542,0.0003264882,0.0001257673,0.000682146,0.0015693491,0.0034178377],"category_scores_gemma":[0.00010643346,0.00057366,0.0005559158,0.00033831346,0.00035119182,0.00014837742,0.00007391536,0.0021996317,0.0015225629],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001428707,0.00009470037,0.00012847388,0.000078331286,0.00066030637,0.00040321492,0.000233712,5.5013743e-7,0.009750168,0.0000061702217,0.98574096,0.0027605304],"study_design_scores_gemma":[0.0018718796,0.0002649965,0.002012292,0.00040302414,0.0006922776,0.00003815565,0.000021010452,0.00023062633,0.04224518,0.0009661297,0.95065576,0.0005986981],"about_ca_topic_score_codex":0.0005173101,"about_ca_topic_score_gemma":0.000012950911,"teacher_disagreement_score":0.09279877,"about_ca_system_score_codex":0.0002219732,"about_ca_system_score_gemma":0.00039268294,"threshold_uncertainty_score":0.99972683},"labels":[],"label_agreement":null},{"id":"W2885361471","doi":"10.1101/385948","title":"Melatonin: The smart molecule that differentially modulates autophagy in tumor and normal placental cells","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique; Université du Québec à Montréal","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Melatonin; Cell biology; Apoptosis; Trophoblast; Biology; Endocrinology; Internal medicine; Chemistry; Placenta; Biochemistry; Medicine; Fetus","score_opus":0.009795506277613468,"score_gpt":0.2159284442353942,"score_spread":0.20613293795778073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2885361471","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99391925,0.003392223,0.00010173385,0.00020524708,0.00091614306,0.0011027751,0.00012281557,0.00021251754,0.000027310909],"genre_scores_gemma":[0.9977648,0.0004439475,0.00038510148,0.00067978684,0.00041795374,0.00014983099,8.9116986e-7,0.0001380513,0.000019602981],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973099,0.00015306205,0.00048398032,0.00092273514,0.00048122279,0.0006490874],"domain_scores_gemma":[0.9979791,0.00006417091,0.0002947648,0.0011619157,0.00015129102,0.00034878007],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003682239,0.0006431249,0.00072780525,0.00022929064,0.00017250127,0.0001647764,0.00041758706,0.00040502253,0.00022665676],"category_scores_gemma":[0.00003983794,0.0005136624,0.00019870662,0.0002419471,0.0003516328,0.0001124904,0.0005531255,0.00088623044,0.000065076856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007341886,0.0008925061,0.065122224,0.00090059085,0.0008701083,0.0010981099,0.00011404776,0.000031370375,0.92919797,0.00043399463,0.00059679296,0.000008125999],"study_design_scores_gemma":[0.001440835,0.000095608986,0.3716057,0.00034503458,0.00019773202,1.865125e-7,0.0000050728113,0.0014218426,0.6241007,0.0000045532006,0.00035860678,0.00042411112],"about_ca_topic_score_codex":0.00007229239,"about_ca_topic_score_gemma":0.0000049009154,"teacher_disagreement_score":0.30648348,"about_ca_system_score_codex":0.00018261644,"about_ca_system_score_gemma":0.00048510754,"threshold_uncertainty_score":0.9997315},"labels":[],"label_agreement":null},{"id":"W2885829694","doi":"10.1101/387563","title":"ULK-mediated phosphorylation of ATG16L1 promotes xenophagy, but destabilizes the ATG16L1 Crohn’s mutant","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"ATG16L1; ULK1; Autophagy; Phosphorylation; Cell biology; Kinase; Biology; Chemistry; Protein kinase A; AMPK; Biochemistry; Apoptosis","score_opus":0.014741682572272628,"score_gpt":0.23892544008203354,"score_spread":0.2241837575097609,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2885829694","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98919046,0.005816162,0.00033240436,0.0003583722,0.0010475534,0.0023247886,0.00044387713,0.0004565607,0.000029842528],"genre_scores_gemma":[0.9962483,0.0009238747,0.0011037677,0.0003425199,0.00082283554,0.00032153202,0.0000039961656,0.00021367455,0.000019469238],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9960355,0.00023298421,0.0010646405,0.0011091449,0.00085018505,0.00070752035],"domain_scores_gemma":[0.99477506,0.00025824155,0.000947288,0.0023391987,0.0012735026,0.0004066919],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009257282,0.0008061868,0.0011183223,0.00027249835,0.0002510637,0.000110821464,0.0006962211,0.00081147073,0.00049301906],"category_scores_gemma":[0.0007392825,0.0006242041,0.00040628682,0.0006785076,0.0007678126,0.00014465519,0.0004036274,0.00092568033,0.00014679105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010284683,0.0009115543,0.01730079,0.0013369557,0.0010747033,0.00022116548,0.000117491676,0.000014082009,0.97717613,0.00028787143,0.0005203048,0.000010501525],"study_design_scores_gemma":[0.0012907557,0.0003113182,0.2855378,0.0007345978,0.0005734661,1.1047783e-7,0.000011615294,0.000592497,0.7093074,0.000019532226,0.0010679277,0.0005529819],"about_ca_topic_score_codex":0.000109988054,"about_ca_topic_score_gemma":0.000002919404,"teacher_disagreement_score":0.26823702,"about_ca_system_score_codex":0.0003255714,"about_ca_system_score_gemma":0.001593854,"threshold_uncertainty_score":0.9996209},"labels":[],"label_agreement":null},{"id":"W2886249166","doi":"10.1080/15548627.2018.1491488","title":"Contractile activity attenuates autophagy suppression and reverses mitochondrial defects in skeletal muscle cells","year":2018,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Canada","keywords":"Autophagy; Mitophagy; TFEB; Cell biology; Biology; Mitochondrion; Mitochondrial biogenesis; PINK1; Lysosome; Skeletal muscle; BAG3; Bafilomycin; Biochemistry; Endocrinology","score_opus":0.010951845977588887,"score_gpt":0.2766579397785881,"score_spread":0.2657060938009992,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886249166","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954202,0.00068975904,0.00005238152,0.00017912798,0.0010838934,0.00060748175,0.00002382934,0.00014511315,0.0017982143],"genre_scores_gemma":[0.996896,0.00013543158,0.0003499637,0.0005868313,0.0007913274,0.0000417966,0.0000152184675,0.000044274304,0.0011391551],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998238,0.0001263741,0.0002841377,0.00055661035,0.00029513903,0.00049972074],"domain_scores_gemma":[0.998878,0.00021061495,0.0001288745,0.00043937078,0.00008243085,0.00026068362],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001347498,0.00029308134,0.000489116,0.00016431288,0.00014592904,0.00003971534,0.000107360735,0.00023565863,0.0008602067],"category_scores_gemma":[0.00011455952,0.00025817045,0.00013233733,0.00021877425,0.00028994435,0.0003075143,0.00008288086,0.0003020262,0.00019459343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046842702,0.0005600292,0.0008157788,0.00007787745,0.00006865842,0.00039388234,0.000513127,0.0000014034918,0.9668941,0.000115782415,0.0028150694,0.02727586],"study_design_scores_gemma":[0.004328272,0.0005596309,0.28151867,0.00012659305,0.00008827725,0.00003830956,0.00005990793,0.00062051706,0.6997843,0.0003318347,0.012273629,0.00027004498],"about_ca_topic_score_codex":0.00018861123,"about_ca_topic_score_gemma":0.00003953929,"teacher_disagreement_score":0.2807029,"about_ca_system_score_codex":0.00007257493,"about_ca_system_score_gemma":0.00013829561,"threshold_uncertainty_score":0.99998707},"labels":[],"label_agreement":null},{"id":"W2886417193","doi":"10.1038/s41598-018-29900-x","title":"A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Okanagan University College; University of British Columbia, Okanagan Campus; Centre for Drug Research and Development; University of British Columbia; BC Cancer Agency; Simon Fraser University","funders":"Simon Fraser University; Avon Foundation for Women; Natural Sciences and Engineering Research Council of Canada; National Cancer Institute; Government of Canada; Canadian Institutes of Health Research","keywords":"Quinoline; Autophagy; Cysteine protease; Cysteine; Protease; Chemistry; Biochemistry; Combinatorial chemistry; Computational biology; Biology; Enzyme; Organic chemistry","score_opus":0.011967436258447749,"score_gpt":0.2671577313522818,"score_spread":0.25519029509383406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886417193","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887534,0.0008467559,0.0005057376,0.0021678898,0.003100724,0.0018995727,0.0000026262396,0.00034392352,0.0023794188],"genre_scores_gemma":[0.9798002,0.0000012242538,0.0009943664,0.00060008024,0.0006027037,0.00008246273,0.00009001895,0.000038741004,0.01779019],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997007,0.00005463898,0.0007142451,0.00090114196,0.00083860697,0.0004843368],"domain_scores_gemma":[0.9971542,0.000025501833,0.00033982375,0.0016538958,0.00036069372,0.00046590628],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010037832,0.00025334363,0.0003127568,0.00014379364,0.00035047712,0.00014307811,0.00018318143,0.00015211986,0.001137113],"category_scores_gemma":[0.00032293907,0.00016031077,0.00022592893,0.0009045436,0.00070306653,0.000111033325,0.0000744146,0.00025605783,0.00030428334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041153442,0.0006516844,0.0015533603,0.00012061982,0.00017094561,0.0022967947,0.0009594556,0.000005852677,0.9113469,0.00032566593,0.0696764,0.012480792],"study_design_scores_gemma":[0.0014754396,0.00025217215,0.00089958,0.00024964235,0.00013228897,0.00084764394,0.000020806956,0.0006161683,0.92372674,0.00592036,0.06562882,0.0002303657],"about_ca_topic_score_codex":0.000032865526,"about_ca_topic_score_gemma":0.000004055848,"teacher_disagreement_score":0.0154107725,"about_ca_system_score_codex":0.00007975098,"about_ca_system_score_gemma":0.0014119273,"threshold_uncertainty_score":0.999776},"labels":[],"label_agreement":null},{"id":"W2887856797","doi":"10.1007/s00253-018-9304-y","title":"Autophagy gene overexpression in Saccharomyces cerevisiae perturbs subcellular organellar function and accumulates ROS to accelerate cell death with relevance to sparkling wine production","year":2018,"lang":"en","type":"article","venue":"Applied Microbiology and Biotechnology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Agriculture, Food and Rural Affairs; University of Guelph","keywords":"Autolysis (biology); Yeast; Wine; Saccharomyces cerevisiae; Programmed cell death; Biology; Autophagy; Cell biology; Yeast in winemaking; Biochemistry; Reactive oxygen species; Intracellular; Mutant; Gene; Apoptosis; Food science; Enzyme","score_opus":0.009991290348910766,"score_gpt":0.22951176758190128,"score_spread":0.2195204772329905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887856797","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99479663,0.0012731034,0.0006722711,0.0020890504,0.00008032747,0.0008985776,0.000007632868,0.00014340432,0.00003898976],"genre_scores_gemma":[0.99484867,0.0004437771,0.0029366203,0.0013021396,0.00019320202,0.000041985764,0.0000483424,0.00002987608,0.00015539407],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99853814,0.00002887022,0.00024655994,0.00077175855,0.00003963768,0.00037505745],"domain_scores_gemma":[0.99939466,0.00003150801,0.00008596407,0.0003299771,0.000054703414,0.000103212245],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014098773,0.00026945598,0.00040053477,0.00027190623,0.00015221143,0.000013646233,0.00009626493,0.00051295944,0.000059027312],"category_scores_gemma":[0.000026059703,0.00020425524,0.000017986029,0.00034733425,0.00021055722,0.000047108413,0.00011842639,0.00027751256,0.000048040307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001850998,0.000099396064,0.0013447636,0.000060693994,0.00003896041,0.00001535931,0.00013865573,0.000008888644,0.9938364,0.0001574317,0.00015467736,0.0022937732],"study_design_scores_gemma":[0.0013755513,0.0012091203,0.005042035,0.00012753981,0.000049989758,0.00013361145,0.00008036798,0.000018660627,0.9868489,0.00026806808,0.0046096765,0.00023648827],"about_ca_topic_score_codex":0.000014661655,"about_ca_topic_score_gemma":0.000007821161,"teacher_disagreement_score":0.006987511,"about_ca_system_score_codex":0.000037808328,"about_ca_system_score_gemma":0.000036222387,"threshold_uncertainty_score":0.8329287},"labels":[],"label_agreement":null},{"id":"W2888023575","doi":"10.1113/jp275998","title":"Autophagy and mitophagy flux in young and aged skeletal muscle following chronic contractile activity","year":2018,"lang":"en","type":"article","venue":"The Journal of Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; York University","keywords":"Mitophagy; Autophagy; Mitochondrion; Skeletal muscle; Cell biology; Flux (metallurgy); Biology; Mitochondrial biogenesis; Endocrinology; Internal medicine; Lysosome; Ageing; Chemistry; Medicine; Biochemistry; Apoptosis","score_opus":0.009446010310928496,"score_gpt":0.2835355338206411,"score_spread":0.2740895235097126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2888023575","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99657696,0.00256841,0.00002581243,0.00018798713,0.00033774183,0.00011955641,0.0000011547415,0.0000075034422,0.00017486924],"genre_scores_gemma":[0.99866813,0.00025007466,0.00003397977,0.00022544451,0.000718921,0.0000015902904,5.921044e-7,0.0000119503375,0.00008930428],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99917924,0.00018845928,0.00021181155,0.000106637104,0.000105916544,0.00020790394],"domain_scores_gemma":[0.99937105,0.00019058351,0.00017421617,0.00014402211,0.000039556795,0.000080565835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003565912,0.000113775524,0.00036303813,0.00007326732,0.00009256585,0.0000065914055,0.0000810573,0.00007558104,0.000118726326],"category_scores_gemma":[0.000055796365,0.0000729255,0.000083907886,0.000076672404,0.00024222425,0.00013411844,0.000037072386,0.0003103596,0.000004202031],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042816342,0.00009640806,0.00068388064,0.000018275863,0.00013349537,0.000048848946,0.000565202,0.000001135629,0.9926172,0.000021863772,0.000081312995,0.005304248],"study_design_scores_gemma":[0.0030692907,0.0010815625,0.9175356,0.000055091983,0.000104163395,0.00027542489,0.000111639645,0.00018882225,0.076594055,0.00070308096,0.0002105738,0.000070698465],"about_ca_topic_score_codex":0.00004431415,"about_ca_topic_score_gemma":0.000040473853,"teacher_disagreement_score":0.9168517,"about_ca_system_score_codex":0.00004845641,"about_ca_system_score_gemma":0.000098661425,"threshold_uncertainty_score":0.29738155},"labels":[],"label_agreement":null},{"id":"W2888806144","doi":"10.1080/15548627.2018.1509609","title":"Diverse mechanisms of autophagy dysregulation and their therapeutic implications: does the shoe fit?","year":2018,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia; BC Cancer Agency; Canada's Michael Smith Genome Sciences Centre; Simon Fraser University","funders":"Cambridge Institute for Medical Research, University of Cambridge; Genome Science Institute, Boston University; BC Cancer Agency; Simon Fraser University; Canadian Institutes of Health Research; Canada's Michael Smith Genome Sciences Centre; BC Cancer Foundation; New England Biolabs","keywords":"Autophagy; Biology; Cell biology; Neuroscience; Genetics; Apoptosis","score_opus":0.02501972760192039,"score_gpt":0.2927521953828337,"score_spread":0.2677324677809133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2888806144","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99002486,0.0013491963,0.0046562892,0.0017589347,0.00028481922,0.0006654722,0.000035253353,0.00013725682,0.0010879315],"genre_scores_gemma":[0.9966988,0.00014833202,0.00030472977,0.0018164254,0.00021947632,0.000035086472,0.000015590484,0.000027071448,0.00073451485],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989483,0.000070932314,0.0002875158,0.0002917012,0.00016820391,0.00023339115],"domain_scores_gemma":[0.9988267,0.00013625492,0.00014939946,0.0006297588,0.00016125278,0.00009663103],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021174086,0.00019631835,0.00027555382,0.00008540243,0.00023342259,0.000021533255,0.00017517152,0.000109126624,0.0005706501],"category_scores_gemma":[0.000028369197,0.00010306158,0.000112509915,0.00022107968,0.0003970631,0.000114224975,0.000068840985,0.00010444905,0.000033213702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000473802,0.000553178,0.0017199647,0.00011838661,0.00081991556,0.00001037884,0.005514721,0.000004557807,0.4089866,0.19905679,0.0005409714,0.38220072],"study_design_scores_gemma":[0.0015058193,0.0006464126,0.3555551,0.00005578457,0.00020390106,0.000055075245,0.00093097973,0.0017044379,0.50694984,0.1298384,0.0023537078,0.00020050725],"about_ca_topic_score_codex":0.000035303194,"about_ca_topic_score_gemma":0.00001043421,"teacher_disagreement_score":0.3820002,"about_ca_system_score_codex":0.000029542673,"about_ca_system_score_gemma":0.0000796836,"threshold_uncertainty_score":0.62482184},"labels":[],"label_agreement":null},{"id":"W2889160320","doi":"10.1101/407593","title":"Gp78 E3 ubiquitin ligase mediates both basal and damage-induced mitophagy","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Mitochondrion; Autophagy; Cell biology; PINK1; Ubiquitin ligase; Parkin; Biology; Endoplasmic reticulum; Mitochondrial fission; Autophagosome; ATG5; Ubiquitin; Biochemistry; Apoptosis; Internal medicine; Medicine","score_opus":0.01581564078322462,"score_gpt":0.25183185931719393,"score_spread":0.2360162185339693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2889160320","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99251485,0.0035822785,0.000050995535,0.00054685056,0.0013605156,0.0010789878,0.00022581565,0.0005859407,0.000053782976],"genre_scores_gemma":[0.99228984,0.00096508727,0.0016134243,0.001751502,0.0028880907,0.0002134221,0.000002107731,0.0002514603,0.000025045245],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962895,0.00016834988,0.00070643285,0.0013958553,0.0006188443,0.0008210328],"domain_scores_gemma":[0.9962228,0.00012451204,0.00044322445,0.001779137,0.00048241625,0.00094791147],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00059922796,0.00086924847,0.001086931,0.0003863633,0.00021990071,0.00019452693,0.00045604445,0.00090727257,0.00036699392],"category_scores_gemma":[0.00034244615,0.00085655594,0.0002554646,0.00037029397,0.00033226094,0.00016335075,0.00056573655,0.0010146479,0.00018018892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000385078,0.0005767713,0.013237592,0.0012566426,0.00084358704,0.0011166123,0.000052629373,0.0000010714422,0.9792576,0.00028998998,0.0029702622,0.000012168266],"study_design_scores_gemma":[0.0020241758,0.00029957484,0.27336824,0.00073529826,0.00043596193,1.01127e-7,0.000006486238,0.00019858874,0.7203919,0.000018033079,0.0017012438,0.0008203636],"about_ca_topic_score_codex":0.000058014062,"about_ca_topic_score_gemma":0.000002044906,"teacher_disagreement_score":0.26013064,"about_ca_system_score_codex":0.00019526995,"about_ca_system_score_gemma":0.0011021235,"threshold_uncertainty_score":0.9993885},"labels":[],"label_agreement":null},{"id":"W2889171161","doi":"10.1038/s41418-018-0185-5","title":"CALCOCO2/NDP52 and SQSTM1/p62 differentially regulate coxsackievirus B3 propagation","year":2018,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; University of British Columbia","keywords":"Capsid; Sequestosome 1; Biology; Autophagy; Coxsackievirus; Cell biology; Viral protein; Virology; Interferon; Ubiquitin; Viral replication; Signal transducing adaptor protein; Virus; Signal transduction; Enterovirus; Biochemistry; Apoptosis","score_opus":0.013087565642482112,"score_gpt":0.25170379526113906,"score_spread":0.23861622961865694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2889171161","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937939,0.00087067205,0.0021348258,0.000117733965,0.0001900396,0.0004726509,0.000008634346,0.00008336238,0.0023281581],"genre_scores_gemma":[0.99698216,0.0004817221,0.00013247425,0.00027599788,0.000341206,0.000021799107,0.00015086604,0.00002399898,0.0015897728],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989635,0.000046254776,0.0002328669,0.0003314194,0.0002021497,0.00022385851],"domain_scores_gemma":[0.99932724,0.000019477753,0.00010867517,0.00021661005,0.000108473454,0.00021954907],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007171618,0.00019331486,0.00023804941,0.00009555137,0.00018876822,0.00006670711,0.000039939358,0.00012563553,0.00022766861],"category_scores_gemma":[0.000017687627,0.00015552391,0.00005279555,0.000076100274,0.00010157561,0.000121793484,0.000034898312,0.000093263174,0.000030118945],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002870058,0.0014348223,0.21508157,0.0012305931,0.00041476768,0.000053053845,0.0025902549,8.365938e-7,0.5786392,0.008024817,0.0015568896,0.1881031],"study_design_scores_gemma":[0.002875954,0.00046502016,0.8963679,0.000079821235,0.00026983206,0.000014628577,0.000027270557,0.003920928,0.09367341,0.0015849216,0.0005110102,0.0002092858],"about_ca_topic_score_codex":0.00002717572,"about_ca_topic_score_gemma":0.00000767785,"teacher_disagreement_score":0.68128633,"about_ca_system_score_codex":0.000025017336,"about_ca_system_score_gemma":0.000035249675,"threshold_uncertainty_score":0.63420814},"labels":[],"label_agreement":null},{"id":"W2889196632","doi":"10.1080/15548627.2018.1491494","title":"CASP4/caspase-11 promotes autophagosome formation in response to bacterial infection","year":2018,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Phagosome; Biology; Burkholderia cenocepacia; Autophagy; Autophagosome; Phagolysosome; Cell biology; Intracellular parasite; Inflammasome; Microbiology; Legionella pneumophila; Intracellular; Bacteria; Inflammation; Apoptosis; Immunology; Biochemistry; Burkholderia","score_opus":0.01739160550371195,"score_gpt":0.3012460331125204,"score_spread":0.28385442760880847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2889196632","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99620765,0.0000554614,0.00032914928,0.0009610092,0.0007056309,0.00084184395,0.000013014448,0.00025031128,0.00063591474],"genre_scores_gemma":[0.99650633,0.000010065693,0.00042692345,0.0011634958,0.00075714744,0.00010886733,0.00004418547,0.000038613638,0.000944381],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998381,0.00017094615,0.0004192235,0.00034532935,0.0002729636,0.00041053296],"domain_scores_gemma":[0.99902016,0.000074509924,0.00009463367,0.00043109924,0.00013891686,0.00024066327],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00043144982,0.00022353204,0.0003202614,0.00043904272,0.00011160527,0.000043089152,0.00009304899,0.00016782644,0.0010789016],"category_scores_gemma":[0.00029582044,0.00020887834,0.000096808646,0.000567653,0.00007630231,0.00037510367,0.000051841467,0.00013648569,0.00088504254],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009493691,0.00081793626,0.003490621,0.00011950719,0.0000740212,0.00065364194,0.0044661122,0.0000073846363,0.9578222,0.00067300326,0.0022966957,0.020085156],"study_design_scores_gemma":[0.0035649058,0.0018147592,0.49416122,0.00014342536,0.000043535823,0.00023365856,0.000032331332,0.00067479996,0.48017547,0.0004618841,0.018419905,0.000274108],"about_ca_topic_score_codex":0.0002224537,"about_ca_topic_score_gemma":0.00017238464,"teacher_disagreement_score":0.4906706,"about_ca_system_score_codex":0.00023655428,"about_ca_system_score_gemma":0.00015283206,"threshold_uncertainty_score":0.9998929},"labels":[],"label_agreement":null},{"id":"W2889591431","doi":"10.1091/mbc.e18-07-0434","title":"Dysfunctional peroxisomes compromise gut structure and host defense by increased cell death and Tor-dependent autophagy","year":2018,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates - Health Solutions; Fraternal Order of Eagles","keywords":"Biology; Autophagy; Cell biology; Dysfunctional family; Programmed cell death; Host (biology); Peroxisome; Apoptosis; Genetics; Gene","score_opus":0.0051736747699002335,"score_gpt":0.23303143093418868,"score_spread":0.22785775616428844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2889591431","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99321854,0.0053764717,0.0001420019,0.00020680827,0.00012832886,0.00026722217,0.00010768972,0.000018845236,0.000534107],"genre_scores_gemma":[0.9976494,0.00007152258,0.0003871119,0.0012505634,0.000058865575,0.0000047464414,0.000038063616,0.000017448172,0.0005223303],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991652,0.0001084788,0.0001583571,0.00028281895,0.00010575994,0.00017939523],"domain_scores_gemma":[0.99939275,0.000034134187,0.000095394484,0.00030221147,0.000057466612,0.000118038624],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007269098,0.00016913009,0.00024581375,0.000039259787,0.00010234253,0.0000066980833,0.00010860323,0.00016343732,0.00017048497],"category_scores_gemma":[0.000017150887,0.000113650894,0.000071013485,0.000045467354,0.00042521508,0.000014448743,0.000100219404,0.00012683975,0.000004307133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025208495,0.000097775206,0.0142107755,0.00004248488,0.000075646036,0.000011358886,0.00007086051,3.1932024e-7,0.9846031,0.00011295321,0.00040920364,0.00011343442],"study_design_scores_gemma":[0.0024161118,0.00048563967,0.034331877,0.000012426047,0.0001399182,0.000047469788,0.000025786092,0.00006760439,0.9607268,0.00085209217,0.00077860005,0.00011567255],"about_ca_topic_score_codex":0.00005783324,"about_ca_topic_score_gemma":0.0000016114918,"teacher_disagreement_score":0.023876302,"about_ca_system_score_codex":0.000017319193,"about_ca_system_score_gemma":0.00005079625,"threshold_uncertainty_score":0.4634549},"labels":[],"label_agreement":null},{"id":"W2890347012","doi":"10.1016/j.isci.2018.09.012","title":"A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress","year":2018,"lang":"en","type":"article","venue":"iScience","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":187,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Gilead Sciences (Canada)","funders":"National Cancer Institute; National Institutes of Health","keywords":"Autophagy; ULK1; Cancer cell; Cell biology; Chemistry; Kinase; Regulator; Cancer research; KRAS; Cancer; Biology; Protein kinase A; Biochemistry; AMPK; Mutation; Apoptosis; Gene","score_opus":0.009362641339626183,"score_gpt":0.28504398664750397,"score_spread":0.2756813453078778,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2890347012","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964091,0.001679441,0.00014484335,0.00081995997,0.00023200933,0.00029947344,0.00003563751,0.000037841364,0.00034170417],"genre_scores_gemma":[0.9974194,0.00022295446,0.00025763942,0.0013579065,0.00026961038,0.00002073398,7.726574e-7,0.0000080933205,0.0004428722],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908435,0.000014493083,0.000099435754,0.00034583398,0.00021624248,0.00023961485],"domain_scores_gemma":[0.99938375,0.000035700108,0.000030706713,0.00014404424,0.000145025,0.00026076072],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007269541,0.000110461595,0.00015205199,0.000064434,0.00015135469,0.000044357672,0.000052200303,0.00003532,0.000041831463],"category_scores_gemma":[0.00003055748,0.00008513527,0.000018066881,0.00021859577,0.00033717783,0.00009867835,0.000069895796,0.000058335107,0.000011926174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035108678,0.00021181429,0.003564095,0.000075384356,0.000044904515,0.00012237894,0.007889195,0.00000975061,0.9666698,0.00031195927,0.0040235166,0.016726108],"study_design_scores_gemma":[0.0005392562,0.00044380513,0.049652923,0.00011496787,0.00002814833,0.000027325026,0.00026011324,0.00033070685,0.9466486,0.00016961677,0.0016745914,0.00010996965],"about_ca_topic_score_codex":0.0001418039,"about_ca_topic_score_gemma":0.00003097268,"teacher_disagreement_score":0.04608883,"about_ca_system_score_codex":0.000031187734,"about_ca_system_score_gemma":0.000116850366,"threshold_uncertainty_score":0.34717155},"labels":[],"label_agreement":null},{"id":"W2891790842","doi":"10.1371/journal.pgen.1007561","title":"Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy","year":2018,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Institutes of Health; Michael J. Fox Foundation for Parkinson's Research","keywords":"Autophagy; Neurodegeneration; Biology; Cell biology; Regulator; Epigenetics; Methyltransferase; Neuroscience; Biochemistry; Disease; Methylation; Internal medicine; Medicine","score_opus":0.01670645489945852,"score_gpt":0.2687521481225612,"score_spread":0.25204569322310266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891790842","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965314,0.0016322937,0.0004970303,0.00032760625,0.00015058318,0.0005023814,0.000038027305,0.00010158849,0.00021903365],"genre_scores_gemma":[0.9960589,0.00017293885,0.0008987102,0.0018510962,0.0005660973,0.000039917875,0.00006152339,0.000051709405,0.00029914096],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986878,0.000086256754,0.00029941168,0.0003566385,0.00029344278,0.00027644125],"domain_scores_gemma":[0.9991988,0.000055427336,0.00006377815,0.00031249347,0.00012692974,0.00024260135],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007520748,0.00020236091,0.00025890477,0.000056544897,0.00015994579,0.000041770145,0.000073167095,0.00010284408,0.00015573592],"category_scores_gemma":[0.00004892689,0.00019282383,0.000061942126,0.00009805194,0.00017129951,0.00005042175,0.000024674247,0.0001488578,0.000021054939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012410781,0.00029020713,0.0061826464,0.000024113671,0.00005124933,0.000014747153,0.00013478495,0.00000538363,0.9859108,0.000058232607,0.00027609654,0.006927652],"study_design_scores_gemma":[0.0020931147,0.0010632297,0.029218048,0.000025765157,0.00035299885,0.00003348479,0.000012755831,0.011066534,0.9549967,0.00010161229,0.0008460079,0.00018975495],"about_ca_topic_score_codex":0.0000038311223,"about_ca_topic_score_gemma":0.0000026555979,"teacher_disagreement_score":0.030914085,"about_ca_system_score_codex":0.000017966438,"about_ca_system_score_gemma":0.00006544379,"threshold_uncertainty_score":0.78631276},"labels":[],"label_agreement":null},{"id":"W2892291982","doi":"10.1016/j.yexcr.2018.09.009","title":"Metabolic profiling associated with autophagy of human placenta-derived mesenchymal stem cells by chemical isotope labeling LC−MS","year":2018,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China; International Business Machines Corporation","keywords":"Metabolome; Metabolite; Biology; Autophagy; Metabolic pathway; Metabolomics; Biochemistry; Metabolism; Pipecolic acid; Mesenchymal stem cell; Derivatization; Amino acid; Mass spectrometry; Chemistry; Cell biology; Chromatography; Bioinformatics; Apoptosis","score_opus":0.05151918776572673,"score_gpt":0.37266571309605634,"score_spread":0.3211465253303296,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2892291982","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98748076,0.004673867,0.00000736352,0.000028637709,0.00007689799,0.0009631429,0.00003131186,0.000085990345,0.006652015],"genre_scores_gemma":[0.9959852,0.000042471336,0.00036045103,0.00008272792,0.00016851546,0.00009978018,0.00008934891,0.00007822432,0.003093255],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966226,0.00027164005,0.00043158256,0.00056371005,0.0013080337,0.0008024109],"domain_scores_gemma":[0.9985529,0.00012545685,0.0001329403,0.0004624259,0.00035054755,0.00037569494],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000693608,0.0002787821,0.00055034336,0.00017601482,0.00028998728,0.00004118461,0.00031385972,0.0001818352,0.0012331359],"category_scores_gemma":[0.000017940907,0.00022834179,0.000121766854,0.0004977134,0.0006978816,0.00011546454,0.00018543552,0.0005127314,0.00008917884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007461,0.0015386769,0.0005815964,0.00004352124,0.00019030769,0.000045989716,0.0014217694,3.851784e-7,0.99417716,0.000110026485,0.0010447542,0.00009971957],"study_design_scores_gemma":[0.003990827,0.0016889515,0.00014109518,0.00011662579,0.000038672242,0.000004486165,0.0020574648,0.00021245674,0.99120396,0.000010890153,0.00032204646,0.00021253293],"about_ca_topic_score_codex":0.00011100696,"about_ca_topic_score_gemma":0.0000015328468,"teacher_disagreement_score":0.008504451,"about_ca_system_score_codex":0.00021223791,"about_ca_system_score_gemma":0.0002316649,"threshold_uncertainty_score":0.99967986},"labels":[],"label_agreement":null},{"id":"W2892317818","doi":"10.1016/j.nano.2018.09.003","title":"High-content analysis for mitophagy response to nanoparticles: A potential sensitive biomarker for nanosafety assessment","year":2018,"lang":"en","type":"article","venue":"Nanomedicine Nanotechnology Biology and Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fundamental Research Funds for the Central Universities; National Institutes of Health; National Institute of Biomedical Imaging and Bioengineering; Major State Basic Research Development Program of China; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics; National Natural Science Foundation of China; Intramural Research Program; Multiple Sclerosis Scientific Research Foundation","keywords":"Mitophagy; PINK1; Parkin; Mitochondrion; Autophagy; Cell biology; Viability assay; Chemistry; Biophysics; Biology; Cell; Biochemistry; Apoptosis; Medicine; Parkinson's disease","score_opus":0.030955453595530914,"score_gpt":0.35746063291115465,"score_spread":0.32650517931562373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2892317818","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8483195,0.0009807562,0.09133417,0.055703156,0.00092844985,0.0023577348,0.00014567644,0.00020909848,0.000021513855],"genre_scores_gemma":[0.9800686,0.00019584627,0.00851846,0.008833281,0.0008675293,0.000559909,0.00028286487,0.000044188724,0.00062932237],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968471,0.00017405668,0.0008648789,0.0010541161,0.00021158016,0.000848296],"domain_scores_gemma":[0.99712056,0.00073818845,0.00026543517,0.0006796913,0.0007371594,0.00045898452],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0016454922,0.0004694733,0.001552508,0.001406834,0.0004158094,0.0000054164716,0.00020243801,0.0007584174,0.00013741989],"category_scores_gemma":[0.0012802613,0.00033109155,0.00026337194,0.001220046,0.0021623024,0.000046670375,0.00010295233,0.00024263017,0.000009859005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.022008566,0.00025419862,0.0038140041,0.00005794036,0.0027237674,0.000061121405,0.00030761043,8.596487e-7,0.945764,0.0035105746,0.0013385719,0.020158751],"study_design_scores_gemma":[0.051786724,0.055353496,0.35403994,0.00046665125,0.009368384,0.00048138545,0.0024637848,0.0012764096,0.47171122,0.0059128962,0.04609668,0.0010424063],"about_ca_topic_score_codex":0.00007850013,"about_ca_topic_score_gemma":0.00002648154,"teacher_disagreement_score":0.4740528,"about_ca_system_score_codex":0.0001378112,"about_ca_system_score_gemma":0.00023657159,"threshold_uncertainty_score":0.9999141},"labels":[],"label_agreement":null},{"id":"W2894332242","doi":"10.1002/jcb.27467","title":"Association of single nucleotide autophagy‐related protein 5 gene polymorphism rs2245214 with susceptibility to non–small cell lung cancer","year":2018,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Yasuj University of Medical Sciences; Manitoba Health Research Council","keywords":"ATG5; Genotype; Lung cancer; Allele; Biology; Single-nucleotide polymorphism; Gene; Oncology; Internal medicine; Logistic regression; Autophagy; Genetics; Cancer research; Apoptosis; Medicine","score_opus":0.005496676848311156,"score_gpt":0.2311194600721146,"score_spread":0.22562278322380344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2894332242","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99626416,0.0014589856,0.0005060014,0.00043910797,0.00014879045,0.00034060027,0.000016708684,0.000016871225,0.0008087872],"genre_scores_gemma":[0.99261576,0.00001993686,0.0013966613,0.00015033784,0.0006452182,0.0000058451283,0.000009172103,0.00003592622,0.005121127],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983463,0.000039523627,0.0006179828,0.00022519646,0.000496936,0.00027402368],"domain_scores_gemma":[0.99774015,0.000021644539,0.0008734872,0.0003315334,0.0007310827,0.00030208356],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041203172,0.00020119171,0.00044096223,0.00008127371,0.00005337679,0.0000155362,0.00017387727,0.00021271182,0.00060791714],"category_scores_gemma":[0.00006433938,0.00016417759,0.00019946226,0.0002554975,0.00008014646,0.00005274616,0.00003116427,0.00026830198,0.000007349089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006477926,0.000553137,0.008038412,0.00023578483,0.00036435868,0.000097753116,0.00026595118,0.000005949288,0.98888195,5.0691455e-7,0.0007209427,0.00018743996],"study_design_scores_gemma":[0.0023296631,0.0007924013,0.0032559575,0.00043291505,0.00040316366,0.000028196673,0.000058062877,0.0000628512,0.9923322,0.000016236818,0.00012742833,0.00016089146],"about_ca_topic_score_codex":0.000029758025,"about_ca_topic_score_gemma":0.0000029550963,"teacher_disagreement_score":0.004782454,"about_ca_system_score_codex":0.00041980672,"about_ca_system_score_gemma":0.00053198094,"threshold_uncertainty_score":0.6694968},"labels":[],"label_agreement":null},{"id":"W2894959416","doi":"10.1016/j.jcjd.2018.08.037","title":"Failure of Autophagy and Lysosomes Exacerbates β-cell Dysfunction and Death Under Hypoxic Stress","year":2018,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autophagy; Medicine; Lipotoxicity; Hypoxia (environmental); Programmed cell death; Cell biology; Islet; Inflammation; Homeostasis; Diabetes mellitus; Apoptosis; Immunology; Internal medicine; Endocrinology; Biology; Insulin resistance; Biochemistry; Chemistry","score_opus":0.009022429269976704,"score_gpt":0.2190030077389996,"score_spread":0.2099805784690229,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2894959416","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888819,0.010128368,0.000011540558,0.00043544985,0.00013520142,0.000070606766,0.000020284499,0.0000044377457,0.00031221056],"genre_scores_gemma":[0.9990118,0.000074978394,0.00013854135,0.00032624276,0.00023620969,8.38791e-7,0.0000028914917,0.000015000501,0.0001934952],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9993442,0.000023922776,0.0002185697,0.00010041878,0.00010584902,0.00020698804],"domain_scores_gemma":[0.9989805,0.00005534236,0.0001482883,0.000104858525,0.00017077461,0.00054020796],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010262556,0.0001100918,0.00026684633,0.00022373612,0.000074676136,0.000023882387,0.000052941767,0.00007554752,0.00021591752],"category_scores_gemma":[0.000036990124,0.00008889258,0.00005152347,0.000087448156,0.00018542592,0.00011815571,0.0000063884386,0.000104857165,0.0000021709147],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003254294,0.00007208662,0.9521278,0.00025757833,0.0004066104,0.0000443892,0.00074550946,0.000005730316,0.037029605,0.00042245755,0.0017333018,0.007122369],"study_design_scores_gemma":[0.0022097356,0.0012496717,0.8309058,0.00032361064,0.00029317552,0.000029109777,0.0006327076,0.00008075046,0.16076909,0.0022637835,0.0010962124,0.00014633246],"about_ca_topic_score_codex":0.00013486831,"about_ca_topic_score_gemma":0.0006617768,"teacher_disagreement_score":0.12373948,"about_ca_system_score_codex":0.000036601643,"about_ca_system_score_gemma":0.00038979825,"threshold_uncertainty_score":0.36249343},"labels":[],"label_agreement":null},{"id":"W2895301426","doi":"10.1371/journal.pone.0205189","title":"LC3B is not recruited along with the autophagy elongation complex (ATG5-12/16L1) at HCV replication site and is dispensable for viral replication","year":2018,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Viral replication; Biology; ATG5; Virology; RNA-dependent RNA polymerase; Replication factor C; Alphavirus; Sindbis virus; Cell biology; RNA; Autophagy; Virus; DNA replication; Control of chromosome duplication; Genetics; Gene","score_opus":0.09620095582114681,"score_gpt":0.3073910686515842,"score_spread":0.21119011283043743,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2895301426","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98526335,0.00012053461,0.0005942205,0.011212092,0.000015414147,0.0019491708,0.00008702068,0.00013090565,0.0006273121],"genre_scores_gemma":[0.9842611,0.00008707544,0.0022334205,0.007302227,0.00034373358,0.0003830694,0.0005628312,0.000046182133,0.0047803936],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984272,0.00005079629,0.00027924718,0.00064060325,0.00035822904,0.00024388531],"domain_scores_gemma":[0.99783075,0.00012312132,0.0002327252,0.0013650634,0.00033078724,0.00011754366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034726405,0.00018061671,0.00027808215,0.00006516981,0.00044129541,0.00004164346,0.00011012372,0.00009896715,0.0003155601],"category_scores_gemma":[0.000109827255,0.0001296197,0.000053430504,0.00018417885,0.00019718616,0.00016299893,0.000040751307,0.00011363061,0.00009532227],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005240451,0.0015596125,0.031892,0.00038214703,0.001042689,0.0000044019457,0.006581872,6.1628964e-7,0.9124997,0.0009800032,0.01959664,0.020219859],"study_design_scores_gemma":[0.0029378966,0.0010704466,0.32270443,0.00018105912,0.00062986766,0.000012890115,0.00006120148,0.014907021,0.6492465,0.00040408838,0.0075991084,0.0002454917],"about_ca_topic_score_codex":0.00007318715,"about_ca_topic_score_gemma":0.000058244637,"teacher_disagreement_score":0.2908124,"about_ca_system_score_codex":0.00010360443,"about_ca_system_score_gemma":0.000042096075,"threshold_uncertainty_score":0.5285738},"labels":[],"label_agreement":null},{"id":"W2896418617","doi":"10.1111/cns.13062","title":"Rapamycin and FK506 derivative TH2849 could ameliorate neurodegenerative diseases through autophagy with low immunosuppressive effect","year":2018,"lang":"en","type":"article","venue":"CNS Neuroscience & Therapeutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Autophagy; Medicine; Pharmacology; Biology; Genetics; Apoptosis","score_opus":0.01778735250349549,"score_gpt":0.30503693697861134,"score_spread":0.28724958447511584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2896418617","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933,0.001688722,0.0023223918,0.0006022712,0.00047697645,0.0009382278,0.00006288148,0.00018941701,0.0004190692],"genre_scores_gemma":[0.98342454,0.00071766885,0.00017358844,0.014936659,0.00025001864,0.00007394152,0.000012202125,0.00006884795,0.00034253235],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99743927,0.00025897688,0.00028598137,0.0008595586,0.00054769905,0.00060854555],"domain_scores_gemma":[0.9983901,0.00019027945,0.0002069149,0.0006918249,0.00026126704,0.00025966403],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010895414,0.0004881928,0.0005242622,0.00010562781,0.00061156956,0.00015502622,0.00031760687,0.00010404024,0.000048681155],"category_scores_gemma":[0.00005354754,0.00033202572,0.000100448786,0.0007289793,0.0024938197,0.0004579587,0.00010834868,0.00032964768,0.0000216629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035349037,0.0008371301,0.01834606,0.000108218104,0.00022972748,0.0006156847,0.004833276,0.00007146132,0.9622722,0.0006806046,0.0003408531,0.008129882],"study_design_scores_gemma":[0.0041255658,0.009109917,0.12771617,0.00019850337,0.00056824,0.00023300873,0.00020943291,0.0028231456,0.848771,0.0005466055,0.005077844,0.00062057446],"about_ca_topic_score_codex":0.000011984195,"about_ca_topic_score_gemma":0.0000024183516,"teacher_disagreement_score":0.1135012,"about_ca_system_score_codex":0.000041810694,"about_ca_system_score_gemma":0.0002751311,"threshold_uncertainty_score":0.99991316},"labels":[],"label_agreement":null},{"id":"W2897648707","doi":"10.1080/15548627.2018.1535292","title":"Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration","year":2018,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":430,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Fondazione Regionale per la Ricerca Biomedica; European Molecular Biology Organization; Regione Lombardia; Ministero dell’Istruzione, dell’Università e della Ricerca; Ministero della Salute; Hsinchu Science Park Bureau, Ministry of Science and Technology, Taiwan; Fondazione Cariplo; Associazione Italiana per la Ricerca sul Cancro; International Brain Research Organization; Fondazione Telethon; Università degli Studi di Milano","keywords":"TFEB; Autophagy; Biology; Degeneration (medical); Cell biology; Lysosome; Trehalose; Biochemistry; Neuroscience; Enzyme; Apoptosis; Pathology","score_opus":0.023761423701373074,"score_gpt":0.2809962543279946,"score_spread":0.2572348306266215,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897648707","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947503,0.00026049843,0.0016971405,0.00020536024,0.00024043773,0.00056565955,0.000009730946,0.0001367217,0.0021341539],"genre_scores_gemma":[0.99779415,0.000057852772,0.000507523,0.0007266183,0.00034806505,0.000057341877,0.00012431004,0.000048516857,0.00033559397],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981207,0.00011544763,0.00058797677,0.0004254431,0.0004023498,0.0003480547],"domain_scores_gemma":[0.9988681,0.00009171103,0.00023232572,0.00046089146,0.00019790807,0.00014904063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018977367,0.00025754163,0.0004512557,0.00039160275,0.00007290642,0.000014484117,0.00014629024,0.00023852068,0.00034395143],"category_scores_gemma":[0.00008472399,0.00024214931,0.00011583862,0.00058654696,0.00015855535,0.0004252918,0.0000391228,0.00019799692,0.000076278244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051045604,0.0007384956,0.0007413873,0.0000641047,0.00007861062,0.000038623293,0.0009844126,0.00015821963,0.98232466,0.0016022179,0.00012688848,0.012631907],"study_design_scores_gemma":[0.0026587471,0.00069838006,0.06578504,0.000088738176,0.00005041136,0.000012144121,0.000033940123,0.029067203,0.89867157,0.0026339085,0.00010370351,0.00019618662],"about_ca_topic_score_codex":0.00018290315,"about_ca_topic_score_gemma":0.00001940789,"teacher_disagreement_score":0.083653085,"about_ca_system_score_codex":0.00010882958,"about_ca_system_score_gemma":0.00021177308,"threshold_uncertainty_score":0.9874562},"labels":[],"label_agreement":null},{"id":"W2898109313","doi":"10.1038/s41420-018-0115-9","title":"Autophagy modulates temozolomide-induced cell death in alveolar Rhabdomyosarcoma cells","year":2018,"lang":"en","type":"article","venue":"Cell Death Discovery","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"British Columbia Knowledge Development Fund; Natural Sciences and Engineering Research Council of Canada; Research Manitoba; National Institute for Medical Research Development; Children's Hospital Research Institute of Manitoba; BC Cancer Foundation; University of Manitoba","keywords":"Autophagy; Temozolomide; Alveolar rhabdomyosarcoma; Programmed cell death; Cancer research; Apoptosis; Medicine; Rhabdomyosarcoma; Biology; Glioblastoma; Pathology; Sarcoma; Genetics","score_opus":0.017942271276998958,"score_gpt":0.26842578027048436,"score_spread":0.2504835089934854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898109313","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97538626,0.0017443969,0.00027092075,0.00009709099,0.0006898978,0.0007320121,0.00003188422,0.00016014591,0.020887414],"genre_scores_gemma":[0.988299,0.00027745476,0.0007338826,0.0014276134,0.00063518557,0.000049075614,0.000063024585,0.00011006447,0.008404669],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99712676,0.000118364325,0.0006194342,0.0008198201,0.00044723263,0.0008684092],"domain_scores_gemma":[0.99822044,0.00012864781,0.00017983827,0.0010103466,0.000095093106,0.000365602],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002620173,0.00051681785,0.00070509786,0.0003016432,0.00016308133,0.00010322727,0.00035909086,0.000316953,0.00048543178],"category_scores_gemma":[0.000026085552,0.00045609052,0.00034200074,0.00036036485,0.00012797536,0.0005204617,0.0001412799,0.00042397872,0.000803963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009837776,0.0021615564,0.049771115,0.0003301455,0.00013250143,0.0012320332,0.00079816673,0.00003434129,0.94096756,0.0006952237,0.001702163,0.0011914363],"study_design_scores_gemma":[0.0039868634,0.00072911335,0.099481806,0.00014374084,0.0001411815,0.000025708401,0.000108208675,0.0012364101,0.89034784,0.0014504945,0.0018462643,0.0005023454],"about_ca_topic_score_codex":0.00023116825,"about_ca_topic_score_gemma":0.000012598205,"teacher_disagreement_score":0.050619673,"about_ca_system_score_codex":0.00020087733,"about_ca_system_score_gemma":0.00035152366,"threshold_uncertainty_score":0.999974},"labels":[],"label_agreement":null},{"id":"W2898330669","doi":"10.1007/s00424-018-2225-x","title":"Regulation of autophagic and mitophagic flux during chronic contractile activity-induced muscle adaptations","year":2018,"lang":"en","type":"article","venue":"Pflügers Archiv - European Journal of Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Occupational Cancer Research Centre; York University","funders":"Natural Sciences and Engineering Research Council of Canada; York University","keywords":"Mitophagy; Autophagy; Skeletal muscle; Biology; Cell biology; Mitochondrion; TFEB; Mitochondrial biogenesis; Internal medicine; Flux (metallurgy); Endocrinology; Chemistry; Biochemistry; Medicine; Apoptosis","score_opus":0.01660454481763997,"score_gpt":0.2643882092936344,"score_spread":0.24778366447599443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898330669","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997326,0.00041152883,0.00015987206,0.00026395015,0.0002100564,0.00013450674,0.0000047778976,0.000017073935,0.0014722226],"genre_scores_gemma":[0.9982476,0.00013426012,0.00033563774,0.00008086536,0.0010192301,8.6735906e-7,0.00000474346,0.00003021902,0.00014656842],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99866265,0.0003664344,0.0004128292,0.00018120225,0.00015460837,0.00022226799],"domain_scores_gemma":[0.99882966,0.000111071015,0.0005206285,0.00022331013,0.00015684636,0.00015845915],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002423938,0.00014491024,0.0003815153,0.00019129177,0.00011849796,0.000007502035,0.00011227435,0.00002850213,0.00025172197],"category_scores_gemma":[0.00006368335,0.00012233033,0.00014636053,0.000113559254,0.0002830421,0.00015752636,0.00003803285,0.00025665824,0.000023562721],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00067707157,0.00012641988,0.00005687665,0.000054717642,0.00017017886,0.000049957955,0.00062800094,0.000021422527,0.97558486,0.00007172349,0.00005875904,0.022500021],"study_design_scores_gemma":[0.002341755,0.0013815225,0.7624393,0.00010427433,0.000103368526,0.00012700477,0.000060678845,0.00044584388,0.23224773,0.000350279,0.00031579635,0.00008241313],"about_ca_topic_score_codex":0.0000038551716,"about_ca_topic_score_gemma":9.40053e-7,"teacher_disagreement_score":0.76238245,"about_ca_system_score_codex":0.000039669587,"about_ca_system_score_gemma":0.00013224337,"threshold_uncertainty_score":0.49884862},"labels":[],"label_agreement":null},{"id":"W2898864613","doi":"10.1165/rcmb.2018-0169oc","title":"Autophagy Activation in Asthma Airways Remodeling","year":2018,"lang":"en","type":"article","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":165,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Health and Medical Research Council; National Heart, Lung, and Blood Institute; Medical Research Council; National Institutes of Health; Clifford Craig Foundation","keywords":"Autophagy; Asthma; Respiratory epithelium; Medicine; Airway; Inflammation; Immunology; Epithelium; Lung; Pathology; Biology; Internal medicine; Apoptosis","score_opus":0.009303462644869694,"score_gpt":0.292630092611636,"score_spread":0.2833266299667663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898864613","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98874855,0.0010681216,0.009258468,0.00014726934,0.000065948174,0.00005990503,5.1414594e-7,0.0000064047804,0.00064483396],"genre_scores_gemma":[0.9943515,0.00008394946,0.0014375455,0.003925913,0.00017673368,0.0000011208501,0.0000010029806,0.000011712521,0.000010544339],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992246,0.000119943565,0.0002835813,0.00013453387,0.000079219615,0.00015810206],"domain_scores_gemma":[0.99937314,0.00002520637,0.00024240404,0.00011659424,0.00012365582,0.00011898278],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022851296,0.00009661386,0.00028030662,0.00020405979,0.0000294682,0.0000045129495,0.000061160994,0.000054316002,0.000026298678],"category_scores_gemma":[0.000036177695,0.000077243705,0.00006917594,0.00016422114,0.00029295328,0.000037184873,0.00001728248,0.00016419574,0.000003305697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044430373,0.00007101246,0.0017892951,0.000006998689,0.000027627464,0.00006835744,0.00013672325,0.000004968626,0.8851031,0.00016387926,0.000031428153,0.11215233],"study_design_scores_gemma":[0.0026513673,0.009221586,0.0100807035,0.00009005183,0.00003921431,0.00011023483,0.00032015084,0.00014276664,0.9471385,0.0009603103,0.029065588,0.00017954719],"about_ca_topic_score_codex":0.00001161473,"about_ca_topic_score_gemma":7.5784527e-7,"teacher_disagreement_score":0.11197278,"about_ca_system_score_codex":0.000027333459,"about_ca_system_score_gemma":0.00014215091,"threshold_uncertainty_score":0.3149907},"labels":[],"label_agreement":null},{"id":"W2899027440","doi":"10.1038/s41419-018-1142-4","title":"YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of General Medical Sciences; University of Pennsylvania; Sarcoma Foundation of America; V Foundation for Cancer Research; National Institutes of Health; American Cancer Society","keywords":"Biology; YAP1; Cell biology; Skeletal muscle; Autophagy; Cancer research; Hippo signaling pathway; Cellular differentiation; Myocyte; Carcinogenesis; Signal transduction; Transcription factor; Endocrinology; Cancer; Apoptosis; Genetics","score_opus":0.00907530129535537,"score_gpt":0.26023942736300254,"score_spread":0.25116412606764715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899027440","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98821753,0.0096769165,0.000009752686,0.000248511,0.0000810189,0.001045459,0.000030037892,0.00007004384,0.0006207333],"genre_scores_gemma":[0.9968605,0.0005721753,0.000045158962,0.0011904928,0.00016395355,0.00011652443,0.000024200732,0.000026682104,0.0010002845],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9984676,0.00014491708,0.00023057924,0.00051917613,0.00028824282,0.0003494431],"domain_scores_gemma":[0.9984354,0.00018031367,0.000068500696,0.0002844626,0.00004148492,0.0009898626],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017675382,0.00027144773,0.00032224468,0.00019581422,0.00012683544,0.000049942195,0.00006452375,0.00011067584,0.000072566036],"category_scores_gemma":[0.00022351538,0.00022052797,0.00004339074,0.00011159635,0.00016733509,0.000089579196,0.00006576997,0.00016294554,0.000029688994],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.06656854,0.00448033,0.39735734,0.0040573934,0.00032438088,0.010838421,0.002765533,0.0000010384919,0.43455008,0.0026132055,0.00080452755,0.0756392],"study_design_scores_gemma":[0.010299046,0.002020486,0.74393314,0.0005010095,0.00016849618,0.000020268639,0.00010283674,0.00029373242,0.23841558,0.0032116976,0.0006226184,0.0004110579],"about_ca_topic_score_codex":0.00004150931,"about_ca_topic_score_gemma":0.000010224702,"teacher_disagreement_score":0.34657583,"about_ca_system_score_codex":0.000033538367,"about_ca_system_score_gemma":0.00019106711,"threshold_uncertainty_score":0.899287},"labels":[],"label_agreement":null},{"id":"W2899384666","doi":"10.1371/journal.pone.0206427","title":"The autophagy inhibitor spautin-1, either alone or combined with doxorubicin, decreases cell survival and colony formation in canine appendicular osteosarcoma cells","year":2018,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Osteosarcoma; Autophagy; Doxorubicin; Chemotherapy; Cancer research; Biology; Programmed cell death; Medicine; Cell; Oncology; Internal medicine; Apoptosis","score_opus":0.01949737352003897,"score_gpt":0.22803097393758662,"score_spread":0.20853360041754765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899384666","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961175,0.00090725656,0.000023949931,0.0006759344,0.000055157172,0.0010833042,0.000015398262,0.00008088478,0.0010406272],"genre_scores_gemma":[0.9967433,0.00025723173,0.0004731383,0.00046652043,0.0002159793,0.00005119289,0.00004559358,0.00004400526,0.0017029886],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984141,0.000116430565,0.0003431617,0.00026707153,0.00047821293,0.0003810121],"domain_scores_gemma":[0.9989356,0.00019153421,0.00015146537,0.0003686677,0.00014138615,0.00021137198],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024688157,0.00023227441,0.00042837247,0.00009236143,0.00020367815,0.00004336693,0.00011285922,0.000093662944,0.00026005946],"category_scores_gemma":[0.00004757981,0.0001372571,0.000035147525,0.00026329877,0.00026441205,0.00013050294,0.000051574578,0.0001663079,0.00007065095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.03229202,0.01358639,0.019370954,0.0009813248,0.001364236,0.0015307562,0.002878685,0.000003103987,0.92272687,0.00050951913,0.0024183292,0.002337818],"study_design_scores_gemma":[0.009512586,0.005170952,0.01533498,0.00045426053,0.00037270054,0.000038722603,0.00043295274,0.0008958829,0.9668755,0.000077613855,0.00058978936,0.00024407529],"about_ca_topic_score_codex":0.00020071969,"about_ca_topic_score_gemma":0.00086968427,"teacher_disagreement_score":0.04414862,"about_ca_system_score_codex":0.0000678936,"about_ca_system_score_gemma":0.0001225815,"threshold_uncertainty_score":0.55971825},"labels":[],"label_agreement":null},{"id":"W2899718426","doi":"10.1139/bcb-2018-0164","title":"Lysophosphatidic acid represses autophagy in prostate carcinoma cells","year":2018,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"Akdeniz Üniversitesi; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; Canadian Institutes of Health Research; Government of Ontario","keywords":"Autophagy; Lysophosphatidic acid; Prostate carcinoma; Prostate; Carcinoma; Biology; Cancer research; Cell biology; Chemistry; Internal medicine; Biochemistry; Medicine; Apoptosis; Cancer; Genetics","score_opus":0.007433208406635508,"score_gpt":0.24720589895904085,"score_spread":0.23977269055240535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899718426","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9835105,0.009416287,0.0000043136997,0.00008982106,0.000114934,0.000145796,0.000017021019,0.000035269146,0.006666037],"genre_scores_gemma":[0.9967642,0.00052968384,0.00011157439,0.00045056498,0.00021638966,0.000014317026,0.00005034067,0.000011181465,0.0018517888],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991161,0.000023423727,0.00019017198,0.00037274676,0.000044903994,0.0002526281],"domain_scores_gemma":[0.9994736,0.000021343727,0.000059712893,0.0002803475,0.00004038376,0.00012462122],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007687315,0.00014771159,0.00021908554,0.00003088204,0.000049015805,0.0000067690644,0.000071074806,0.00015841213,0.00020532262],"category_scores_gemma":[0.000016168411,0.00012432675,0.000035419962,0.00009846647,0.00030560113,0.000018981089,0.000044854307,0.00010424611,0.000034161807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002915205,0.00035261406,0.008947664,0.00011145136,0.000014311154,0.00008005742,0.00013164047,2.2045219e-8,0.98775417,0.00002310215,0.00032826015,0.0019652182],"study_design_scores_gemma":[0.002964497,0.00032843402,0.005391115,0.000022143822,0.00002168609,0.000024268562,0.00006621879,0.000019934963,0.98762584,0.00022048726,0.0031901384,0.00012523873],"about_ca_topic_score_codex":0.000022479784,"about_ca_topic_score_gemma":5.9320547e-7,"teacher_disagreement_score":0.013253638,"about_ca_system_score_codex":0.000018199957,"about_ca_system_score_gemma":0.00009240709,"threshold_uncertainty_score":0.5069897},"labels":[],"label_agreement":null},{"id":"W2899822635","doi":"10.1139/cjz-2018-0104","title":"Autophagy and apoptosis in starved and refed <i>Neocaridina davidi</i> (Crustacea, Malacostraca) midgut","year":2018,"lang":"en","type":"article","venue":"Canadian Journal of Zoology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Hepatopancreas; Midgut; Biology; Epithelium; Apoptosis; Autophagy; Starvation; Malacostraca; Internal medicine; Crustacean; Anatomy; Endocrinology; Cell biology; Decapoda; Biochemistry; Zoology; Ecology; Larva","score_opus":0.014478988541407264,"score_gpt":0.25478182129582483,"score_spread":0.24030283275441755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899822635","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99214715,0.0040684594,0.000012341691,0.0022124944,0.00027807048,0.00011611225,0.000012300229,0.000004875451,0.0011482213],"genre_scores_gemma":[0.99699116,0.00032059103,0.0002877192,0.001868934,0.00020513873,0.0000017680078,0.0000029549853,0.00001708404,0.0003046454],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99898815,0.00007635778,0.00033305032,0.00016666249,0.00008666471,0.00034910667],"domain_scores_gemma":[0.99873406,0.0000560499,0.00013335222,0.00014771718,0.00013294326,0.00079590746],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026871066,0.0001322246,0.00037110533,0.00036744366,0.00007810058,0.000020769949,0.00008448224,0.00016220725,0.00031880883],"category_scores_gemma":[0.00010430111,0.00011988115,0.000046743284,0.00013638167,0.00039498208,0.0001036976,0.000010952442,0.000289976,0.000006912747],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002941416,0.00019958499,0.8970245,0.00018574756,0.00083702017,0.0069724144,0.004695577,0.000003274899,0.027936723,0.003356604,0.010606967,0.045240175],"study_design_scores_gemma":[0.0050489125,0.0025255606,0.96638423,0.00015597732,0.00019597929,0.0022986303,0.00052047096,0.000055498833,0.008942294,0.0019660194,0.011677428,0.00022900722],"about_ca_topic_score_codex":0.0022193757,"about_ca_topic_score_gemma":0.012088593,"teacher_disagreement_score":0.06935973,"about_ca_system_score_codex":0.00010040485,"about_ca_system_score_gemma":0.00088080385,"threshold_uncertainty_score":0.6745719},"labels":[],"label_agreement":null},{"id":"W2900253406","doi":"10.1016/j.celrep.2019.02.102","title":"The Transcription Factors TFEB and TFE3 Link the FLCN-AMPK Signaling Axis to Innate Immune Response and Pathogen Resistance","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Terry Fox Research Institute; Concordia University; National Institutes of Health; Myrovlytis Trust; Fonds de Recherche du Québec - Santé; Kidney Foundation of Canada; Deutsches Krebsforschungszentrum; National Heart, Lung, and Blood Institute; McGill University","keywords":"TFEB; Innate immune system; Transcription factor; Folliculin; Biology; AMPK; Cell biology; TFE3; Immune system; Basic helix-loop-helix leucine zipper transcription factors; Signal transduction; Transcription (linguistics); Immunology; Protein kinase A; Genetics; Kinase; Gene; DNA-binding protein","score_opus":0.008935760447288534,"score_gpt":0.23453657036972536,"score_spread":0.22560080992243683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2900253406","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9856579,0.011173502,0.000036684705,0.0015605546,0.0002544904,0.00064710295,0.0000043787386,0.00003704865,0.00062838546],"genre_scores_gemma":[0.99199206,0.00043284637,0.000042530814,0.00033101926,0.00006314833,0.000019036966,0.0000088217375,0.000024280194,0.007086254],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988055,0.00012012696,0.00034183552,0.0002962735,0.00022663744,0.00020962911],"domain_scores_gemma":[0.9989024,0.00022544806,0.00013847766,0.0005429031,0.00006371125,0.00012710546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009361447,0.00014879557,0.00019994864,0.000041237876,0.00023561712,0.000051860323,0.00005814949,0.000075741256,0.000041266903],"category_scores_gemma":[0.00010862629,0.00008335331,0.00007157752,0.00012236927,0.00007773407,0.000055256733,0.000024212104,0.00016203604,0.000006823198],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016151632,0.000026509564,0.006357329,0.000056076915,0.000051938743,0.00029966014,0.0028835896,0.000004739067,0.9865136,0.000027169328,0.00014090173,0.0020232936],"study_design_scores_gemma":[0.0010395303,0.00037729123,0.5307531,0.00023535475,0.00018252488,0.00014209888,0.0012085678,0.000030065597,0.3440375,0.0011913393,0.120490916,0.00031174772],"about_ca_topic_score_codex":0.000015446973,"about_ca_topic_score_gemma":0.0000039816027,"teacher_disagreement_score":0.64247614,"about_ca_system_score_codex":0.000026516063,"about_ca_system_score_gemma":0.00007310321,"threshold_uncertainty_score":0.33990493},"labels":[],"label_agreement":null},{"id":"W2900861399","doi":"10.1111/dmcn.14092","title":"Autophagy in childhood neurological disorders","year":2018,"lang":"en","type":"review","venue":"Developmental Medicine & Child Neurology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Cambridge Institute for Medical Research, University of Cambridge; China Scholarship Council; Commonwealth Scholarship Commission; Alzheimer Society; National Institutes of Health; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research; NIHR Cambridge Biomedical Research Centre; Alzheimer's Research Foundation; Rosetrees Trust; Gates Cambridge Trust; Department of Health and Social Care; Cambridge Trust; Wellcome Trust; Medical Research Council; National Institute on Handicapped Research; Wellcome","keywords":"Autophagy; Neurodegeneration; Hereditary spastic paraplegia; Neuroscience; Ataxia; Biology; Medicine; Phenotype; Genetics; Gene; Pathology; Disease","score_opus":0.026010598625139065,"score_gpt":0.3182844180723608,"score_spread":0.29227381944722175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2900861399","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0036398128,0.97901195,0.0000025826232,0.0035106544,0.0013291864,0.0020573451,0.000016728447,0.00023444481,0.0101973],"genre_scores_gemma":[0.0012174492,0.9761301,0.000062963234,0.020310398,0.0011935864,0.00026408184,0.00044840403,0.00016381853,0.00020919392],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99511456,0.0004499306,0.0014890047,0.0014798769,0.0004985066,0.0009681039],"domain_scores_gemma":[0.99819505,0.00033178745,0.00039659507,0.0005963901,0.00003119524,0.00044899381],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00034006394,0.0010567307,0.0034729163,0.0009279367,0.00014854164,0.000008935741,0.0005741477,0.0009332412,0.002091708],"category_scores_gemma":[0.0003363932,0.00075329054,0.00046837865,0.00090161053,0.0008076972,0.000060420673,0.0002805701,0.0019761925,0.0005907061],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026184568,0.0008748142,0.00081948,0.0021371045,0.00031783222,0.0019486003,0.00024522445,8.495062e-8,3.1153027e-7,0.00013430169,0.0041073356,0.9891531],"study_design_scores_gemma":[0.0030479652,0.0024418707,0.0267308,0.003265847,0.00049982435,0.0043610553,0.0000048187535,0.000002758884,0.000001275085,0.00020298772,0.95893055,0.0005102343],"about_ca_topic_score_codex":0.000015419382,"about_ca_topic_score_gemma":0.000023592176,"teacher_disagreement_score":0.9886428,"about_ca_system_score_codex":0.00008059743,"about_ca_system_score_gemma":0.0005317194,"threshold_uncertainty_score":0.9994918},"labels":[],"label_agreement":null},{"id":"W2901327288","doi":"10.1016/j.abb.2018.11.004","title":"Mitochondrial breakdown in skeletal muscle and the emerging role of the lysosomes","year":2018,"lang":"en","type":"review","venue":"Archives of Biochemistry and Biophysics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mitophagy; Lysosome; Cell biology; Biogenesis; Mitochondrion; Autophagy; Mitochondrial biogenesis; Biology; Organelle biogenesis; Skeletal muscle; Autophagosome; Chemistry; Biochemistry; Endocrinology; Enzyme; Gene","score_opus":0.006993370459422501,"score_gpt":0.261701299853578,"score_spread":0.2547079293941555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901327288","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.060491547,0.93822855,9.432202e-7,0.00004818958,0.00004711873,0.0003168853,0.00006773712,0.000004259886,0.00079480186],"genre_scores_gemma":[0.05744455,0.94198066,0.000047847912,0.00001819643,0.00033919126,0.000014767959,0.000029292389,0.00001344185,0.00011205471],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991921,0.000054432847,0.00030739544,0.00021183779,0.000114502334,0.000119739365],"domain_scores_gemma":[0.9991615,0.00017915272,0.00025143055,0.00035444248,0.000011930017,0.00004158755],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004436217,0.00019595386,0.00071129017,0.000025168792,0.00004656943,0.000005716367,0.0001711137,0.000087842796,0.0000044115945],"category_scores_gemma":[0.000026936741,0.0000981358,0.00034811415,0.000120246186,0.0011629474,0.000014157552,0.00014000443,0.00018073618,3.1010265e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000111332956,0.00015123794,0.000021816122,0.009786221,0.00033192657,0.0000022759016,0.0005242882,2.7289937e-8,0.017845338,0.00032837995,0.000017423814,0.97087973],"study_design_scores_gemma":[0.017098706,0.0006451613,0.0028181842,0.08720408,0.008501559,0.00023156709,0.0015995171,0.00020023501,0.33422768,0.0343497,0.51122826,0.0018953427],"about_ca_topic_score_codex":0.000015029097,"about_ca_topic_score_gemma":3.5124452e-7,"teacher_disagreement_score":0.96898437,"about_ca_system_score_codex":0.0000033409415,"about_ca_system_score_gemma":0.000105498264,"threshold_uncertainty_score":0.42849278},"labels":[],"label_agreement":null},{"id":"W2901703782","doi":"10.1126/scisignal.aap9921","title":"IFN-γ–inducible antiviral responses require ULK1-mediated activation of MLK3 and ERK5","year":2018,"lang":"en","type":"article","venue":"Science Signaling","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; U.S. Department of Veterans Affairs","keywords":"Protein kinase R; ASK1; Cyclin-dependent kinase 9; STAT1; MAP kinase kinase kinase; Cell biology; Cyclin-dependent kinase 2; Mitogen-activated protein kinase kinase; Biology; Kinase; ULK1; TANK-binding kinase 1; STAT protein; MAP2K7; Activator (genetics); Protein kinase A; Cancer research; Signal transduction; Biochemistry; Receptor; STAT3; AMPK","score_opus":0.03117026262358171,"score_gpt":0.3341691843138596,"score_spread":0.3029989216902779,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901703782","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977671,0.000098935096,0.0002820848,0.00024883644,0.000096672586,0.00013379904,0.000003980052,0.000036890688,0.0013316855],"genre_scores_gemma":[0.9988059,0.000013885309,0.00052870065,0.0002577872,0.00014240065,0.0000024288988,0.0000025491445,0.0000072859234,0.0002390893],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989596,0.00003080747,0.00016746139,0.0002620829,0.00036481852,0.00021523671],"domain_scores_gemma":[0.9993161,0.00009537683,0.000091789014,0.00020106253,0.00019989148,0.00009578733],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074777036,0.00007982209,0.00014319387,0.00021695002,0.00020353924,0.00002301614,0.000098546225,0.00004248752,0.00009889143],"category_scores_gemma":[0.0004781846,0.00006515636,0.000026434047,0.00070422265,0.0009962601,0.00045307135,0.000033889104,0.00006942891,0.000012778726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002564957,0.000035823643,0.0032020567,0.000016835804,0.000008531658,0.0000043462387,0.00066237187,6.1527265e-7,0.9921854,0.00024705252,0.000024364052,0.0033560984],"study_design_scores_gemma":[0.000515058,0.0003636248,0.022744032,0.00015449313,0.000014084008,0.0000053749027,0.000333499,0.00057042943,0.97442454,0.00064664724,0.00015431848,0.00007388212],"about_ca_topic_score_codex":0.00001953516,"about_ca_topic_score_gemma":5.5547883e-7,"teacher_disagreement_score":0.019541975,"about_ca_system_score_codex":0.000026409261,"about_ca_system_score_gemma":0.0003411844,"threshold_uncertainty_score":0.3670762},"labels":[],"label_agreement":null},{"id":"W2901854852","doi":"10.1038/s41564-018-0293-5","title":"An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread","year":2018,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; University of Toronto; University Health Network; St. Michael's Hospital; Princess Margaret Cancer Centre; Hospital for Sick Children","funders":"","keywords":"ATG16L1; Cell biology; Autophagy; Cell membrane; Biology; Listeria monocytogenes; Membrane; Chemistry; Biochemistry; Bacteria; Apoptosis","score_opus":0.01057123845117661,"score_gpt":0.273939398089731,"score_spread":0.26336815963855437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901854852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933605,0.003354458,0.000013513358,0.00035469045,0.00061585556,0.0006557571,0.00013584987,0.00022072849,0.0012886022],"genre_scores_gemma":[0.99273986,0.00013278573,0.0017494535,0.0028317482,0.00064309576,0.000022467842,0.00019375037,0.000049584298,0.0016372609],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99842834,0.00012091936,0.0002698789,0.00069069996,0.00006843099,0.00042175158],"domain_scores_gemma":[0.99884415,0.000056865498,0.000095708296,0.0005789162,0.00014846626,0.0002759053],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017003497,0.00030952867,0.0004500499,0.0001369462,0.000121042336,0.0000204819,0.00019071784,0.00078060996,0.00025314797],"category_scores_gemma":[0.000029720795,0.0002449594,0.00010391957,0.00012701371,0.00018351185,0.000059074937,0.00007692405,0.00040573278,0.00016165727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010007294,0.00035705647,0.0012274602,0.00009749245,0.00007714276,0.000115547606,0.0005776206,3.7479245e-7,0.99393165,0.000033593293,0.001255976,0.0013253712],"study_design_scores_gemma":[0.002003725,0.0021688496,0.0017730615,0.00004553578,0.0000867283,0.00033499917,0.00007068913,0.000027681272,0.96549547,0.00003213028,0.027701141,0.00025998507],"about_ca_topic_score_codex":0.000015762816,"about_ca_topic_score_gemma":0.00004448857,"teacher_disagreement_score":0.028436162,"about_ca_system_score_codex":0.000039179424,"about_ca_system_score_gemma":0.00010541548,"threshold_uncertainty_score":0.9989155},"labels":[],"label_agreement":null},{"id":"W2902081462","doi":"10.1139/bcb-2018-0226","title":"Ginsenoside metabolite compound K induces apoptosis and autophagy in non-small cell lung cancer cells via AMPK–mTOR and JNK pathways","year":2018,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autophagy; AMPK; PI3K/AKT/mTOR pathway; Apoptosis; Chemistry; A549 cell; Protopanaxadiol; Ginsenoside; Cell biology; Signal transduction; Cancer research; Cell growth; Protein kinase B; Acridine orange; Kinase; Biology; Protein kinase A; Biochemistry; Ginseng; Medicine","score_opus":0.010344657536669377,"score_gpt":0.2503462051736051,"score_spread":0.24000154763693574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902081462","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97558653,0.022332784,0.000019094643,0.00008379796,0.00016428022,0.00022876526,0.000060889786,0.000027199327,0.0014966469],"genre_scores_gemma":[0.9945808,0.0036302977,0.00020247915,0.0006886702,0.00045545155,0.00003800761,0.00004619792,0.000019040088,0.0003390654],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988023,0.00003478884,0.00024842794,0.00051553064,0.00005501222,0.0003439575],"domain_scores_gemma":[0.99936724,0.0000582063,0.000105116276,0.00021578702,0.000048583664,0.00020506601],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011068147,0.00026335937,0.00041019422,0.00006115288,0.00009950488,0.00002145326,0.00007978762,0.00032117404,0.00008882827],"category_scores_gemma":[0.0000059140684,0.00022557113,0.000043472057,0.00010127482,0.00041274572,0.000033928172,0.000085780805,0.00018332334,0.0000038229505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015120787,0.00012901601,0.0061424137,0.0003467422,0.000045820947,0.000014137471,0.00033297052,7.8412754e-8,0.9907646,0.000010972071,0.00012304644,0.0019390009],"study_design_scores_gemma":[0.0017814485,0.00013327244,0.0071236114,0.00004790766,0.000117575146,0.000011829071,0.00012041629,0.00011639284,0.9887229,0.000089012974,0.0014963702,0.000239252],"about_ca_topic_score_codex":0.000194452,"about_ca_topic_score_gemma":0.00000591647,"teacher_disagreement_score":0.018994248,"about_ca_system_score_codex":0.000024159584,"about_ca_system_score_gemma":0.00008414204,"threshold_uncertainty_score":0.9198524},"labels":[],"label_agreement":null},{"id":"W2903393356","doi":"10.1080/21505594.2018.1551010","title":"The Intertwined Life Cycles of Enterovirus and Autophagy","year":2018,"lang":"en","type":"review","venue":"Virulence","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Biology; Mitophagy; Obligate; Neurodegeneration; Viral replication; Virology; Virus; Genetics; Disease; Medicine","score_opus":0.04942296111247398,"score_gpt":0.373237598610355,"score_spread":0.32381463749788103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2903393356","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010394697,0.9976341,0.000019639652,0.000027961263,0.00026255863,0.00044686717,0.000031158008,0.000037475078,0.00050077465],"genre_scores_gemma":[0.00070046936,0.9980137,0.000039988598,0.00028346642,0.00027698686,0.000046996858,0.000008232791,0.00003277031,0.0005974082],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987519,0.00009198745,0.000483388,0.00028383348,0.00019255746,0.00019637994],"domain_scores_gemma":[0.9987287,0.00023196485,0.00029498327,0.000552521,0.000052619263,0.00013921827],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019481085,0.0002567663,0.0009169019,0.000074974494,0.0000810257,0.000020744772,0.00026340943,0.00014958704,0.000074378935],"category_scores_gemma":[0.00016596029,0.00014006424,0.0002786462,0.00012275885,0.0004075011,0.00003816923,0.00011101235,0.00018718466,0.00009145108],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006157501,0.00005814803,0.000014870062,0.0059933257,0.00035115797,0.000020676116,0.00006783589,2.537765e-9,0.000010609978,0.00022682684,0.00082966423,0.9923653],"study_design_scores_gemma":[0.00028782908,0.00022818148,0.00014916972,0.0107929595,0.00063316943,0.000042305008,0.000013002338,0.000007320083,0.000104583276,0.00013876929,0.9874652,0.00013751804],"about_ca_topic_score_codex":0.000010125548,"about_ca_topic_score_gemma":0.0000011553838,"teacher_disagreement_score":0.9922278,"about_ca_system_score_codex":0.000022886941,"about_ca_system_score_gemma":0.00023459883,"threshold_uncertainty_score":0.5711653},"labels":[],"label_agreement":null},{"id":"W2904439964","doi":"10.1080/15548627.2018.1558002","title":"Knockdown of BNIP3L or SQSTM1 alters cellular response to mitochondria target drugs","year":2018,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; University of Waterloo","funders":"Government of Canada; Canadian Hematology Society; Leukemia and Lymphoma Society of Canada; Leukemia Research Foundation","keywords":"Autophagy; Biology; Myeloid leukemia; Mitochondrion; Cell biology; Mitophagy; Mitochondrial ROS; Gene knockdown; Mitochondrial DNA; Cancer research; Reactive oxygen species; Haematopoiesis; Stem cell; Apoptosis; Genetics; Gene","score_opus":0.01240266381252354,"score_gpt":0.29620455496756853,"score_spread":0.283801891155045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2904439964","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923489,0.0005464305,0.00090569136,0.0011909982,0.0007634568,0.00064118195,0.000035842557,0.0001492406,0.00341825],"genre_scores_gemma":[0.9744909,0.00001877913,0.005936595,0.0035227027,0.00062951224,0.000045713616,0.000020372645,0.00006023541,0.015275205],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980763,0.00014672999,0.00045598642,0.0004397762,0.0004252936,0.00045587617],"domain_scores_gemma":[0.9982412,0.00016923784,0.0001263513,0.0008425477,0.00020125977,0.00041940616],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00034081173,0.00026092486,0.0004980811,0.00025000845,0.000097338925,0.000014673264,0.0002588021,0.0001423582,0.004806267],"category_scores_gemma":[0.00024319928,0.00020539474,0.00019245701,0.0004785409,0.0002064214,0.0000874765,0.00008030417,0.00014122145,0.000985585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.017907439,0.00045207335,0.0002663971,0.000083807994,0.00027236328,0.00035070485,0.0039437716,0.00000370475,0.94567424,0.000455721,0.027471391,0.0031183804],"study_design_scores_gemma":[0.0027454852,0.0021392026,0.007341693,0.000121028264,0.0001009254,0.000025865309,0.00021131338,0.0000988557,0.88251525,0.00051606906,0.103937685,0.00024664841],"about_ca_topic_score_codex":0.00004219455,"about_ca_topic_score_gemma":0.0000021029377,"teacher_disagreement_score":0.07646629,"about_ca_system_score_codex":0.00007522585,"about_ca_system_score_gemma":0.00035921365,"threshold_uncertainty_score":0.9997923},"labels":[],"label_agreement":null},{"id":"W2905471522","doi":"10.14740/gr1075w","title":"Autophagy Related-Protein 16-1 Up-Regulated in Hepatitis B Virus-Related Hepatocellular Carcinoma and Impaired Apoptosis","year":2018,"lang":"en","type":"article","venue":"Gastroenterology Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Graduate School, Kasetsart University; Kasetsart University Research and Development Institute; Kasetsart University","keywords":"ATG5; Autophagy; ATG16L1; HBx; Cancer research; Apoptosis; ATG12; Gene knockdown; Hepatitis B virus; Virology; Medicine; Biology; Virus","score_opus":0.02698034580406433,"score_gpt":0.30972148724938375,"score_spread":0.2827411414453194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2905471522","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961145,0.00065930054,0.000018105957,0.0011709474,0.00020112118,0.0012029423,0.000021861088,0.00013763146,0.00047362113],"genre_scores_gemma":[0.9970268,0.00019694732,0.00007800123,0.000309013,0.00010300169,0.00016506577,0.00008492283,0.000068689485,0.0019675419],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9957629,0.00088020443,0.0006749098,0.0008027053,0.0005623919,0.0013168951],"domain_scores_gemma":[0.9983252,0.00007021577,0.00010380802,0.00070748053,0.00032628633,0.00046696904],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001271672,0.00031808956,0.00062969787,0.00082184264,0.00026102894,0.000033270768,0.00027610984,0.0004330056,0.0009724835],"category_scores_gemma":[0.00014547499,0.00030131807,0.00013602867,0.0007073216,0.0014003724,0.00013484326,0.00025937034,0.0010198235,0.00019518695],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00275467,0.00034098866,0.91027987,0.000056362227,0.00023646699,0.00038452994,0.00072922796,4.5351922e-7,0.08295034,0.00020169967,0.00088991877,0.0011754725],"study_design_scores_gemma":[0.00802324,0.0038133387,0.9065415,0.0001667502,0.000054589145,0.00029431254,0.00010411599,0.0037202465,0.07504083,0.0018930613,0.00017161113,0.00017639826],"about_ca_topic_score_codex":0.0023020923,"about_ca_topic_score_gemma":0.00048634372,"teacher_disagreement_score":0.007909502,"about_ca_system_score_codex":0.00026770122,"about_ca_system_score_gemma":0.00016654887,"threshold_uncertainty_score":0.9999439},"labels":[],"label_agreement":null},{"id":"W2905488135","doi":"10.1016/j.bbamcr.2018.12.001","title":"Stress is an agonist for the induction of programmed cell death: A review","year":2018,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Military College of Canada; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Defence Academy","keywords":"Programmed cell death; Cell biology; Extracellular; Apoptosis; Mitochondrion; Oxidative stress; Reactive oxygen species; Homeostasis; Caspase; Biology; Unfolded protein response; Cellular adaptation; Agonist; Cell; Endoplasmic reticulum; Receptor; Biochemistry","score_opus":0.1653698153679367,"score_gpt":0.4525010081469142,"score_spread":0.2871311927789775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2905488135","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0049775275,0.9835675,0.000038241455,0.00078099914,0.0001439085,0.009196712,0.0004617352,0.0000623229,0.00077110645],"genre_scores_gemma":[0.0040048184,0.99043864,0.00043871658,0.00044971786,0.00055261946,0.0017027535,0.0014315268,0.00024437282,0.000736843],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9941113,0.0011179623,0.0010140684,0.0012473089,0.001523528,0.0009858244],"domain_scores_gemma":[0.99487555,0.00043251037,0.0006752505,0.0025974293,0.0009605557,0.0004586795],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001612828,0.0007593505,0.0020243407,0.0003694884,0.0003309593,0.00012813121,0.001315849,0.00056589633,0.00009361739],"category_scores_gemma":[0.00014660101,0.0004989489,0.0016640231,0.0012931667,0.00073562335,0.00009116389,0.0003065363,0.0012472433,0.00007962483],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006715939,0.006579849,2.0915327e-7,0.3493619,0.0024719753,0.00011086227,0.00051033066,5.9722176e-8,0.09723214,0.0002732014,0.018351825,0.52443606],"study_design_scores_gemma":[0.0009069923,0.0021098787,0.0000038365088,0.024977604,0.0034355856,0.000013402537,0.000056061468,0.0000187834,0.36238462,0.00012743176,0.6054007,0.0005651305],"about_ca_topic_score_codex":0.00006355764,"about_ca_topic_score_gemma":0.0000011799743,"teacher_disagreement_score":0.5870489,"about_ca_system_score_codex":0.00016143193,"about_ca_system_score_gemma":0.0018748178,"threshold_uncertainty_score":0.9997462},"labels":[],"label_agreement":null},{"id":"W2906273639","doi":"10.1016/j.fsi.2018.12.041","title":"Glutamine starvation inhibits snakehead vesiculovirus replication via inducing autophagy associated with the disturbance of endogenous glutathione pool","year":2018,"lang":"en","type":"article","venue":"Fish & Shellfish Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Guangdong Science and Technology Department; National Natural Science Foundation of China; Department of Education of Guangdong Province; Pakistan Science Foundation","keywords":"Glutathione; Autophagy; Biology; Glutamine; Reactive oxygen species; Buthionine sulfoximine; Biochemistry; Cell biology; Oxidative stress; Intracellular; Apoptosis; Amino acid; Enzyme","score_opus":0.022208900710191333,"score_gpt":0.24733680625207097,"score_spread":0.22512790554187964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2906273639","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99380314,0.00088811794,0.0010169541,0.0019836004,0.00019489406,0.0007713319,0.000051500927,0.00015362845,0.0011368557],"genre_scores_gemma":[0.9969037,0.00010837162,0.0001021604,0.0017633821,0.0002195565,0.00008696619,0.00033777417,0.000049517355,0.0004285753],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99799156,0.00017306233,0.0005398062,0.00052757224,0.00033404556,0.00043392208],"domain_scores_gemma":[0.99758154,0.00019453948,0.0005541345,0.0010618024,0.0005357467,0.00007221333],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042161916,0.0002679604,0.0005023911,0.000122000914,0.0002585315,0.000017684748,0.00025982835,0.00025105377,0.00022887938],"category_scores_gemma":[0.00036334965,0.000194025,0.00009725626,0.00064260623,0.00059090974,0.00016320795,0.00006810258,0.00036019797,0.00003908587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017075373,0.0009785574,0.0039598173,0.000048194375,0.0011395388,0.000065405904,0.0026510358,0.000010186333,0.9618916,0.00035434138,0.0023019938,0.024891775],"study_design_scores_gemma":[0.003194677,0.0022694876,0.35263035,0.00017885331,0.00026631035,0.00017914061,0.00015756002,0.00024195168,0.6372317,0.00030096315,0.0030870778,0.00026192213],"about_ca_topic_score_codex":0.00012999798,"about_ca_topic_score_gemma":0.000078633915,"teacher_disagreement_score":0.34867054,"about_ca_system_score_codex":0.00018610677,"about_ca_system_score_gemma":0.00020826867,"threshold_uncertainty_score":0.79121095},"labels":[],"label_agreement":null},{"id":"W2910114186","doi":"10.4049/jimmunol.1801053","title":"<i>Leishmania donovani</i> Induces Autophagy in Human Blood–Derived Neutrophils","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Autophagy; Lipophosphoglycan; Leishmania donovani; Biology; Cell biology; Innate immune system; Leishmania; CD47; ULK1; Macrophage; Phagocytosis; Kinase; Immune system; Immunology; Protein kinase A; Parasite hosting; Leishmaniasis; Biochemistry; Visceral leishmaniasis; Apoptosis","score_opus":0.01130551354407627,"score_gpt":0.2620889821513316,"score_spread":0.2507834686072553,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2910114186","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99062663,0.006551226,0.0000043603914,0.0011269902,0.00042131316,0.00019992547,9.297667e-7,0.000014680818,0.0010539468],"genre_scores_gemma":[0.9972435,0.0010149291,0.000036885456,0.0011671617,0.00018395041,0.0000016704015,0.0000016010079,0.000021108715,0.0003291737],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99874663,0.00018940057,0.0005325023,0.00009950443,0.00016658593,0.00026535572],"domain_scores_gemma":[0.9989987,0.000102890546,0.00037791074,0.00035931435,0.000109405366,0.00005176276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044749162,0.00014794906,0.00048006265,0.00020468888,0.00005535071,0.000009093174,0.0003497806,0.00012961475,0.00047330375],"category_scores_gemma":[0.00002556311,0.000093347386,0.00012938854,0.00018029768,0.00013820495,0.00011486872,0.000055771772,0.00064545945,0.000066994646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007496779,0.0003064979,0.0016986168,0.000013088026,0.00041188614,0.00021603038,0.00056889636,0.000013251248,0.9943984,0.0006125638,0.0000898347,0.0009212244],"study_design_scores_gemma":[0.0106472485,0.0034540517,0.4436588,0.00020828132,0.0003565436,0.0029032836,0.00065968983,0.000006532612,0.5334422,0.002636516,0.0018274568,0.00019942025],"about_ca_topic_score_codex":0.000040637584,"about_ca_topic_score_gemma":0.0000033203073,"teacher_disagreement_score":0.46095625,"about_ca_system_score_codex":0.000044636432,"about_ca_system_score_gemma":0.0001339896,"threshold_uncertainty_score":0.51823443},"labels":[],"label_agreement":null},{"id":"W2911686738","doi":"10.1083/jcb.201804172","title":"Deubiquitinating enzyme USP30 maintains basal peroxisome abundance by regulating pexophagy","year":2019,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Peroxisome; Deubiquitinating enzyme; Mitophagy; Ubiquitin ligase; Cell biology; Ubiquitin; Organelle; Autophagy; Regulator; Biology; Biochemistry; Receptor; Gene","score_opus":0.007727802545191152,"score_gpt":0.2621763403682735,"score_spread":0.2544485378230823,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911686738","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914852,0.0034805883,0.0004087022,0.0006689871,0.0002966263,0.00015867455,0.0000056894955,0.000014481587,0.0034810554],"genre_scores_gemma":[0.9954658,0.00027527064,0.00040927864,0.0017919817,0.00042580906,0.000001083603,0.0000059117497,0.000024060017,0.0016007647],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986818,0.00023710655,0.00047512096,0.00011884119,0.0001691396,0.0003179908],"domain_scores_gemma":[0.9986233,0.0003412666,0.0005157328,0.00024743908,0.00015308523,0.000119150085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00081927725,0.0001517539,0.00038796422,0.0000726453,0.0000907271,0.000009146664,0.00025332754,0.00011139183,0.0006905545],"category_scores_gemma":[0.00007222111,0.00009285337,0.00015040717,0.000103266735,0.00012385866,0.00007238144,0.000046551035,0.0004057548,0.00006513255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004951229,0.00010781331,0.0020562946,0.00003237039,0.000087836874,0.000019721852,0.00047893325,0.00003384342,0.99404216,0.00037897268,0.0006319263,0.0016349872],"study_design_scores_gemma":[0.0036090966,0.002628323,0.005266922,0.00014001953,0.00015033918,0.00038948448,0.0009671776,0.0005719279,0.9785623,0.002350163,0.0051629385,0.00020132086],"about_ca_topic_score_codex":0.000009413402,"about_ca_topic_score_gemma":7.0197393e-7,"teacher_disagreement_score":0.01547989,"about_ca_system_score_codex":0.00007190523,"about_ca_system_score_gemma":0.00014031483,"threshold_uncertainty_score":0.75610876},"labels":[],"label_agreement":null},{"id":"W2911788128","doi":"10.1113/jp277157","title":"Parkin overexpression protects from ageing‐related loss of muscle mass and strength","year":2019,"lang":"en","type":"article","venue":"The Journal of Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Institut Universitaire de Gériatrie de Montréal; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Parkin; Mitophagy; Ageing; Sarcopenia; Mitochondrion; Skeletal muscle; PINK1; Endocrinology; Internal medicine; Biology; Cell biology; Autophagy; Chemistry; Medicine; Apoptosis; Biochemistry; Parkinson's disease","score_opus":0.007392048258940284,"score_gpt":0.247080589534867,"score_spread":0.2396885412759267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911788128","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983865,0.001076715,0.000008861156,0.00014352678,0.00009037404,0.00014484061,0.0000050587373,0.000004441803,0.0001396646],"genre_scores_gemma":[0.99936175,0.00028200133,0.000066340006,0.0001117165,0.00010071314,6.181883e-7,0.0000024861968,0.000008771036,0.00006559573],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99934,0.0001410885,0.00023998959,0.00006654968,0.00011449532,0.00009787618],"domain_scores_gemma":[0.99923354,0.00014860871,0.00033516667,0.00017650721,0.000054099793,0.000052057036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014388589,0.00007625527,0.0002867581,0.000034618053,0.000021279535,0.0000014892693,0.00009349615,0.0000696007,0.0004484208],"category_scores_gemma":[0.000026414313,0.000041362917,0.00006524214,0.000045730103,0.00008202136,0.00004277295,0.000026140593,0.0002234441,0.000008393373],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009175043,0.00007972605,0.0005728438,0.00003046294,0.00016516935,0.000013550573,0.0003978478,0.00002987517,0.9966065,0.000033879267,0.00007733255,0.0010752828],"study_design_scores_gemma":[0.004198147,0.0013122605,0.59576243,0.00053961686,0.00016269069,0.000039144532,0.00023788298,0.00030770007,0.38200733,0.014961522,0.000386256,0.00008499805],"about_ca_topic_score_codex":0.000021889635,"about_ca_topic_score_gemma":1.8714722e-7,"teacher_disagreement_score":0.6145992,"about_ca_system_score_codex":0.000009104636,"about_ca_system_score_gemma":0.00004017852,"threshold_uncertainty_score":0.49098933},"labels":[],"label_agreement":null},{"id":"W2912925337","doi":"10.1172/jci125980","title":"Ulk1/Rab9-mediated alternative mitophagy confers cardioprotection during energy stress","year":2019,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Cardioprotection; ULK1; Stress (linguistics); Autophagy; Medicine; Biology; Cell biology; Internal medicine; Ischemia; Biochemistry; Kinase","score_opus":0.05551144062152267,"score_gpt":0.3493674525936576,"score_spread":0.2938560119721349,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2912925337","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82672316,0.0012020622,0.00044413077,0.16344035,0.0069042603,0.0005480367,0.00007929452,0.00006186478,0.0005968353],"genre_scores_gemma":[0.4416433,0.002555779,0.00037386565,0.49166757,0.058444038,0.000026262562,0.0006929969,0.00018695531,0.0044092387],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99535066,0.00061220984,0.0022402413,0.0003850183,0.0011074552,0.00030439714],"domain_scores_gemma":[0.994682,0.00077310216,0.0029687502,0.00040387537,0.000874638,0.00029762092],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00078133115,0.00036602304,0.0014847819,0.00039810396,0.000065486274,0.000048485606,0.00024482887,0.0013199856,0.00014624611],"category_scores_gemma":[0.0013788705,0.00029887332,0.0009778157,0.0002081903,0.00027910358,0.0002579785,0.00003399128,0.0033005197,0.000050067858],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0041095517,0.00058042357,0.044892285,0.0020886227,0.010266103,0.009746664,0.00047818065,0.0005773894,0.008500891,0.00008855547,0.9106687,0.008002666],"study_design_scores_gemma":[0.032246273,0.0070034927,0.12872803,0.009475681,0.004122848,0.0020411448,0.00018742794,0.0020871924,0.10693148,0.007137917,0.69801474,0.0020237823],"about_ca_topic_score_codex":0.000066095,"about_ca_topic_score_gemma":0.0000015662507,"teacher_disagreement_score":0.3850799,"about_ca_system_score_codex":0.00017868688,"about_ca_system_score_gemma":0.0008204524,"threshold_uncertainty_score":0.9999765},"labels":[],"label_agreement":null},{"id":"W2914047283","doi":"10.1152/ajpcell.00483.2018","title":"STF-62247 accumulates in lysosomes and blocks late stages of autophagy to selectively target von Hippel-Lindau-inactivated cells","year":2019,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Atlantic Cancer Research Institute; Université de Moncton","funders":"Canadian Institutes of Health Research; New Brunswick Innovation Foundation; Government of Canada; Cancer Research Institute","keywords":"Autophagy; Lysosome; Cell biology; Programmed cell death; Cancer cell; Cytosol; Autophagosome; Biology; Cell; Flux (metallurgy); Cancer research; Chemistry; Cancer; Apoptosis; Biochemistry; Genetics","score_opus":0.005656018418773446,"score_gpt":0.25817613824626723,"score_spread":0.2525201198274938,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2914047283","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998543,0.0005118927,0.000009482924,0.0002041034,0.00020433648,0.00039306018,0.000022330993,0.000021664002,0.00009013131],"genre_scores_gemma":[0.9977089,0.00035144482,0.0006608961,0.0008498082,0.00014497207,0.000006753949,0.000012129642,0.000045797016,0.00021928744],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976489,0.00034513837,0.0007786571,0.00047730235,0.0001995536,0.0005504613],"domain_scores_gemma":[0.9975258,0.00039662427,0.0011873104,0.00035147805,0.00027420736,0.00026455888],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023078661,0.0003724631,0.0016889881,0.00048686753,0.000039726267,0.000005700684,0.00027864953,0.00015345201,0.00032437316],"category_scores_gemma":[0.000053775624,0.0002976541,0.00023176483,0.0005870313,0.00045147946,0.00013184035,0.00010467162,0.0005693409,0.000028549477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0038198715,0.0006649364,0.0057695266,0.000089636036,0.00035451568,0.000021573855,0.0009270709,0.0019384753,0.9853741,0.00001801969,0.00014024117,0.0008820687],"study_design_scores_gemma":[0.002999827,0.006318221,0.32914478,0.00009896587,0.00007519389,0.000019004672,0.0005394678,0.00025718374,0.6590787,0.0010647883,0.00016882316,0.0002350228],"about_ca_topic_score_codex":0.000097673284,"about_ca_topic_score_gemma":0.0000012955413,"teacher_disagreement_score":0.32629535,"about_ca_system_score_codex":0.000084593084,"about_ca_system_score_gemma":0.00026043563,"threshold_uncertainty_score":0.99994755},"labels":[],"label_agreement":null},{"id":"W2914397812","doi":"10.1101/gad.320481.118","title":"Autophagy modulates lipid metabolism to maintain metabolic flexibility for <i>Lkb1</i>-deficient <i>Kras</i>-driven lung tumorigenesis","year":2019,"lang":"en","type":"article","venue":"Genes & Development","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"New Jersey Commission on Cancer Research; National Institutes of Health; National Cancer Institute; American Cancer Society; Cancer Research Society; Lung Cancer Research Foundation","keywords":"Autophagy; Biology; Carcinogenesis; Cell biology; Cancer research; Lipid metabolism; Lung cancer; Cancer; Apoptosis; Biochemistry; Internal medicine; Genetics","score_opus":0.013647647899825654,"score_gpt":0.2790134547988662,"score_spread":0.26536580689904055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2914397812","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97989917,0.0087864045,0.005390816,0.0006127296,0.001331259,0.003266011,0.00005143405,0.0003663195,0.0002958445],"genre_scores_gemma":[0.95194155,0.00046303132,0.039708946,0.0040675136,0.0005102763,0.00097504037,0.00013965499,0.00014909236,0.0020448745],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99643177,0.00007995041,0.0008343347,0.0010398692,0.0006591871,0.00095487665],"domain_scores_gemma":[0.99792266,0.00010487338,0.00015932343,0.00092269195,0.0003170892,0.00057338725],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006481418,0.0005410621,0.0009827025,0.00027640865,0.00023957745,0.000058019006,0.0003653029,0.00015574912,0.0005413373],"category_scores_gemma":[0.00005835718,0.00046912025,0.00035493934,0.00047002686,0.000047949776,0.00011074897,0.0001951666,0.000134017,0.0006066037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004515535,0.003922943,0.051188134,0.0019232233,0.004734377,0.00013776342,0.00920903,0.00979939,0.51940244,0.023878096,0.0073127677,0.3639763],"study_design_scores_gemma":[0.002771053,0.0001392932,0.13936223,0.00008571021,0.00032857092,0.000022583437,0.00019517048,0.0013286485,0.4505101,0.00048005278,0.4040691,0.00070747023],"about_ca_topic_score_codex":0.000031267704,"about_ca_topic_score_gemma":0.000008537936,"teacher_disagreement_score":0.39675632,"about_ca_system_score_codex":0.0002502796,"about_ca_system_score_gemma":0.0007372846,"threshold_uncertainty_score":0.99977607},"labels":[],"label_agreement":null},{"id":"W2914436528","doi":"10.1038/s41419-019-1311-0","title":"SVIP alleviates CCl4-induced liver fibrosis via activating autophagy and protecting hepatocytes","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Science Foundation of Anhui Province; Natural Science Foundation of Liaoning Province; National Natural Science Foundation of China","keywords":"Autophagy; TFEB; Fibrosis; Cell biology; In vivo; Hepatic fibrosis; Hepatic stellate cell; Programmed cell death; Transcription factor; Cancer research; Intracellular; Biology; Chemistry; Medicine; Biochemistry; Pathology; Endocrinology; Apoptosis","score_opus":0.01463967132921521,"score_gpt":0.24091121547378638,"score_spread":0.22627154414457118,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2914436528","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913095,0.0062696734,0.000069730646,0.000088849134,0.0000551634,0.0008147799,0.000008781118,0.00010857336,0.0012749224],"genre_scores_gemma":[0.9977703,0.00024461883,0.00036062527,0.00060705334,0.00012462221,0.000054755947,0.000015297785,0.000033183667,0.0007895605],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989001,0.000049369304,0.00017729471,0.00040547524,0.00016802407,0.00029972917],"domain_scores_gemma":[0.9987626,0.00011523492,0.000082103346,0.00025891056,0.0000437278,0.00073739025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009741876,0.00022293239,0.00026738775,0.00006582477,0.0001833669,0.00005081465,0.00005083926,0.000077221164,0.00040490896],"category_scores_gemma":[0.000095334355,0.00018682546,0.00008624926,0.00007308561,0.000031550375,0.00015610464,0.000062647654,0.0001720231,0.00007042289],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035442766,0.0010675011,0.4902809,0.0041077617,0.00029277545,0.0006435824,0.0019219064,0.000005665321,0.40783814,0.00035440375,0.00019065026,0.08975246],"study_design_scores_gemma":[0.007355936,0.00085341965,0.78214186,0.0006006261,0.00040505867,0.000036932248,0.0003862557,0.016543185,0.18847178,0.0013265017,0.0010709537,0.0008074825],"about_ca_topic_score_codex":0.000052100964,"about_ca_topic_score_gemma":3.0425653e-7,"teacher_disagreement_score":0.29186097,"about_ca_system_score_codex":0.000023651257,"about_ca_system_score_gemma":0.00010932386,"threshold_uncertainty_score":0.76185215},"labels":[],"label_agreement":null},{"id":"W2914831074","doi":"10.3390/ijms20030461","title":"Current Outlook on Autophagy in Human Leukemia: Foe in Cancer Stem Cells and Drug Resistance, Friend in New Therapeutic Interventions","year":2019,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Mitacs; Canadian Cancer Society; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Autophagy; Biology; Cancer stem cell; Cancer cell; Stem cell; Cancer research; Leukemia; Cellular adaptation; Cancer; Pharmacology; Immunology; Cell biology; Apoptosis","score_opus":0.08685606186331239,"score_gpt":0.4340862792872545,"score_spread":0.3472302174239421,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2914831074","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.028482147,0.96970826,0.00004445677,0.00023297177,0.000841794,0.00034700113,0.000010722007,0.0000034053355,0.00032921263],"genre_scores_gemma":[0.054737784,0.94426894,0.00004719346,0.00013319672,0.000107338914,0.000013628219,0.0000032701282,0.000017136426,0.00067152584],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975441,0.00018944641,0.0009932775,0.0003154652,0.00075535674,0.00020234603],"domain_scores_gemma":[0.9989546,0.000090240486,0.0006368412,0.00013329636,0.000083786894,0.00010122888],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068341574,0.00023246728,0.0008431956,0.001313629,0.000023141254,0.00007107592,0.00057498604,0.00009057845,0.00005878252],"category_scores_gemma":[0.000013587863,0.00017547073,0.00039422346,0.0003967602,0.00014361244,0.00014641405,0.000060083294,0.00063197233,0.0000048852753],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012411953,0.0006340375,0.00062487664,0.0025688098,0.00034737022,0.00138994,0.00063019485,0.00025896032,0.00013193404,0.0054524974,0.0002630837,0.98757416],"study_design_scores_gemma":[0.009079016,0.00082301465,0.003699679,0.30393982,0.00083010364,0.00021917377,0.0003886183,0.00012204214,0.0013196504,0.006366017,0.67219174,0.0010211477],"about_ca_topic_score_codex":0.00006972582,"about_ca_topic_score_gemma":0.0002384842,"teacher_disagreement_score":0.986553,"about_ca_system_score_codex":0.0006809809,"about_ca_system_score_gemma":0.0016837729,"threshold_uncertainty_score":0.7155489},"labels":[],"label_agreement":null},{"id":"W2916104137","doi":"10.1111/jfd.12959","title":"Autophagy‐related genes in rainbow trout <i>Oncorhynchus mykiss </i>(Walbaum) gill epithelial cells and their role in nutrient restriction","year":2019,"lang":"en","type":"article","venue":"Journal of Fish Diseases","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Ontario Veterinary College, University of Guelph; Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Agriculture, Food and Rural Affairs","keywords":"Rainbow trout; Biology; Autophagy; ATG12; Gene; BECN1; Nutrient; Trout; Cell biology; Gene expression; Genetics; Zoology; Fishery; Ecology; Apoptosis","score_opus":0.0052924271060069295,"score_gpt":0.22533360230933955,"score_spread":0.2200411752033326,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2916104137","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909319,0.0074172695,0.0000057398174,0.0005828234,0.0002872691,0.0003790706,0.000082750936,0.00002032274,0.00029284926],"genre_scores_gemma":[0.99480224,0.003966002,0.000023630964,0.00070105493,0.00024490742,0.0000071326963,0.000013090528,0.000026371335,0.00021558044],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9983866,0.00013031154,0.0006761694,0.00022499522,0.00029688218,0.0002849958],"domain_scores_gemma":[0.9988983,0.00014329003,0.00033937485,0.00021069843,0.00009778576,0.0003105047],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021182116,0.0002181768,0.0005576918,0.00041392233,0.00003542869,0.000030266383,0.00011984676,0.0001289185,0.00017360636],"category_scores_gemma":[0.00006282629,0.00016516862,0.00021972694,0.00033197057,0.0000558623,0.00025553437,0.000028345568,0.00031416453,0.00001204777],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011635137,0.006461357,0.567176,0.0005162643,0.0007237974,0.0029832157,0.0035151858,0.0009540485,0.3491244,0.0003189347,0.004085555,0.052506123],"study_design_scores_gemma":[0.014161766,0.001249585,0.902312,0.000633241,0.00018937458,0.00017999014,0.001124747,0.0008498864,0.06845828,0.003463559,0.0070605623,0.00031705445],"about_ca_topic_score_codex":0.000035969126,"about_ca_topic_score_gemma":0.0000065791482,"teacher_disagreement_score":0.33513597,"about_ca_system_score_codex":0.00014144334,"about_ca_system_score_gemma":0.00024096719,"threshold_uncertainty_score":0.6735381},"labels":[],"label_agreement":null},{"id":"W2916867214","doi":"10.1080/15548627.2019.1586261","title":"An autophagy-independent role for ATG16L1: promoting lysosome-mediated plasma membrane repair","year":2019,"lang":"en","type":"letter","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; ATG16L1; Lysosome; Biology; Cell biology; Exocytosis; TFEB; Membrane; Homeostasis; Biochemistry; Enzyme; Apoptosis","score_opus":0.013217935345339007,"score_gpt":0.2726881417090961,"score_spread":0.2594702063637571,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2916867214","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.77246547,0.0072054863,0.00027756524,0.17141855,0.008406181,0.019719815,0.0024850804,0.008732496,0.009289329],"genre_scores_gemma":[0.19985688,0.0002926704,0.0026276389,0.7101651,0.020230878,0.0019055041,0.016867086,0.0013993656,0.0466549],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9929767,0.00028302617,0.0013789535,0.002129486,0.0014544191,0.0017773738],"domain_scores_gemma":[0.9950734,0.0006741397,0.00080245396,0.0025489833,0.00042393708,0.00047712078],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"category_scores_codex":[0.0006915136,0.0013362474,0.0021299862,0.0006220823,0.00030253234,0.00014156915,0.00086774764,0.0026669812,0.0015829112],"category_scores_gemma":[0.00028534856,0.0012355665,0.0013999455,0.00041906344,0.0001720627,0.00040215222,0.00013868582,0.002590835,0.0011788434],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020212582,0.0022314026,0.00055458216,0.007175837,0.0054516797,0.008873109,0.0023304503,0.000065806526,0.06386947,0.00027422866,0.89667165,0.010480531],"study_design_scores_gemma":[0.010540201,0.0027317924,0.0019084315,0.00076354924,0.001629105,0.0005062346,0.00010171596,0.023630507,0.07442683,0.00044583358,0.88146216,0.0018536635],"about_ca_topic_score_codex":0.00007360779,"about_ca_topic_score_gemma":0.000005520735,"teacher_disagreement_score":0.5726086,"about_ca_system_score_codex":0.00044506765,"about_ca_system_score_gemma":0.001137577,"threshold_uncertainty_score":0.99993885},"labels":[],"label_agreement":null},{"id":"W2917451824","doi":"10.1186/s12929-019-0512-2","title":"Autophagy: roles in intestinal mucosal homeostasis and inflammation","year":2019,"lang":"en","type":"review","venue":"Journal of Biomedical Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":150,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University Medical Centre; McMaster University; Population Health Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Immune system; Inflammation; Homeostasis; Biology; Intestinal epithelium; Intestinal mucosa; Immunology; Cell biology; Gut flora; Mucosal immunology; Epithelium; Immunity; Medicine; Genetics; Internal medicine; Apoptosis","score_opus":0.03838081149224294,"score_gpt":0.3771875860166791,"score_spread":0.3388067745244362,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2917451824","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007406784,0.9915963,0.00006444488,0.00026519503,0.0003256727,0.00023721057,0.000004883706,0.000007894734,0.00009162516],"genre_scores_gemma":[0.0018760269,0.9969062,0.00070319144,0.00006203437,0.00040535943,0.0000028848006,0.0000046296655,0.000011477987,0.000028148823],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99749476,0.0000674431,0.00089067925,0.00023335524,0.0010351727,0.00027862174],"domain_scores_gemma":[0.99840915,0.00018132242,0.00064701587,0.00016977116,0.00013709487,0.0004556406],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015755586,0.00019778173,0.0011519423,0.001003207,0.000045537796,0.00004906845,0.00033876483,0.0001713149,0.000081973456],"category_scores_gemma":[0.0007049766,0.00012086323,0.00020483212,0.0011741442,0.00079275377,0.00024206715,0.00009159471,0.00058089086,0.000022519911],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022748625,0.00007667082,0.000027110087,0.0021487216,0.000026827169,0.00030140695,0.000049918577,4.550292e-8,0.000058639933,0.00004650893,0.00007085278,0.99717057],"study_design_scores_gemma":[0.001475397,0.001066168,0.002803272,0.032512434,0.000676351,0.004152979,0.000052107844,0.00013063979,0.00007359778,0.0002651398,0.9565197,0.0002722134],"about_ca_topic_score_codex":0.000003303729,"about_ca_topic_score_gemma":4.3979202e-7,"teacher_disagreement_score":0.99689835,"about_ca_system_score_codex":0.00022416255,"about_ca_system_score_gemma":0.0023989724,"threshold_uncertainty_score":0.49286595},"labels":[],"label_agreement":null},{"id":"W2917771798","doi":"10.1016/j.celrep.2019.01.062","title":"AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Autophagy; AMPK; Vesicle; Cell biology; Kinase; Priming (agriculture); Membrane; Chemistry; AMP-activated protein kinase; Protein kinase A; Biology; Biochemistry; Apoptosis; Botany","score_opus":0.012696861764715406,"score_gpt":0.24908916769968656,"score_spread":0.23639230593497115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2917771798","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995433,0.0009237228,0.00005847837,0.000016233695,0.00070551626,0.00057054235,0.0000032078783,0.000057552374,0.002231769],"genre_scores_gemma":[0.9986128,0.00006802513,0.00028408153,0.000035584042,0.00020523512,0.000011029273,0.000029201648,0.000032339736,0.00072171196],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985826,0.000036552123,0.00059845205,0.00030653758,0.00028375495,0.00019208198],"domain_scores_gemma":[0.9987138,0.000046437446,0.0005428642,0.0005188096,0.0001116227,0.00006650067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016260953,0.00016744409,0.00045862142,0.00007430192,0.000028053868,0.0000077992045,0.000052540363,0.00011531084,0.0005780003],"category_scores_gemma":[0.000046851757,0.00014179076,0.0001676404,0.00012000096,0.000057423866,0.0001388316,0.00003161665,0.00008971443,0.0000131911775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029653276,0.0002676162,0.0012462428,0.0006222549,0.00006959755,0.00032561057,0.00054184,0.0000063111293,0.9931025,0.000009837611,0.000011557551,0.0035001133],"study_design_scores_gemma":[0.00085695455,0.00049049035,0.010229137,0.00018705793,0.00013863944,0.00016565432,0.00006305543,0.000031137097,0.98640615,0.0002824293,0.0010324414,0.0001168758],"about_ca_topic_score_codex":0.000061051105,"about_ca_topic_score_gemma":0.000001353628,"teacher_disagreement_score":0.008982894,"about_ca_system_score_codex":0.000030329586,"about_ca_system_score_gemma":0.00013423109,"threshold_uncertainty_score":0.63286984},"labels":[],"label_agreement":null},{"id":"W2918939288","doi":"10.1096/fasebj.31.1_supplement.629.12","title":"Lysosome enlargement in PIKfyve inhibited cells proceeds through homotypic lysosome fusion rather than growth of individual lysosomes","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Toronto Metropolitan University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Lysosome; Cell biology; Chemistry; Biology; Biochemistry; Enzyme","score_opus":0.02431014537800635,"score_gpt":0.2830365468609302,"score_spread":0.25872640148292386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2918939288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99420017,0.0013534615,0.00005087442,0.0015728569,0.00034200842,0.00055359676,0.000023704779,0.000027796928,0.0018755032],"genre_scores_gemma":[0.9968513,0.0010193296,0.00021592187,0.0006855553,0.0005169275,0.000016763493,0.000014767857,0.000046653266,0.00063276105],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975613,0.00014211438,0.000657293,0.00026580456,0.0008684958,0.0005050358],"domain_scores_gemma":[0.99814934,0.000065606895,0.0007114704,0.00067723985,0.00020194158,0.00019440221],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009335253,0.0003097517,0.0005602056,0.00024683724,0.0005371633,0.00014621815,0.0007786156,0.00015112887,0.0005347139],"category_scores_gemma":[0.000096101074,0.0001944047,0.00028373286,0.00023177413,0.00031558936,0.00043818651,0.00021232788,0.0006500682,0.000055140175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002421154,0.0026631516,0.18918623,0.00029891316,0.0013720419,0.00083512213,0.016790431,0.000016644046,0.7766424,0.0024198685,0.0020815304,0.005272521],"study_design_scores_gemma":[0.0077531114,0.00073267514,0.30752283,0.0006493102,0.00040885733,0.0002792338,0.0013530893,0.000052113617,0.67183524,0.008867479,0.00022565131,0.0003203847],"about_ca_topic_score_codex":0.0000475772,"about_ca_topic_score_gemma":0.000007789306,"teacher_disagreement_score":0.11833661,"about_ca_system_score_codex":0.000090726135,"about_ca_system_score_gemma":0.00022167813,"threshold_uncertainty_score":0.7927593},"labels":[],"label_agreement":null},{"id":"W2921309569","doi":"10.15252/embr.201847407","title":"Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart","year":2019,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Deutsche Forschungsgemeinschaft; National Institute of Environmental Health Sciences; Else Kröner-Fresenius-Stiftung; Stem Cell Network; Universität zu Köln; Deutsches Zentrum für Herz-Kreislaufforschung; Bayer","keywords":"Ageing; Personal Integrity; Biology; Structural integrity; Genetics; Psychology; Social psychology","score_opus":0.012432229392865942,"score_gpt":0.28152571453859515,"score_spread":0.2690934851457292,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921309569","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99532473,0.00063049607,0.000005208101,0.00052012847,0.00022330396,0.00036580424,0.0000016761402,0.000022815473,0.0029058228],"genre_scores_gemma":[0.9986156,0.00003490198,0.000038866638,0.0009051768,0.00008563485,0.000011585124,0.000012452091,0.00001335185,0.00028242654],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99896723,0.00005172258,0.0003620833,0.00022240846,0.00022535406,0.00017122239],"domain_scores_gemma":[0.9991524,0.000051642968,0.00017458724,0.00053945277,0.00003381135,0.00004806966],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004391342,0.000106827145,0.00029761376,0.00004199063,0.000022708671,0.000009001818,0.000082678045,0.00007318658,0.00015906556],"category_scores_gemma":[0.0000556135,0.00007389488,0.000094226125,0.000116953895,0.000038712726,0.000057629142,0.000025994927,0.00027779452,0.000019854493],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000072719835,0.0002550883,0.69059134,0.00008340626,0.0000558386,0.0007688214,0.001877327,0.0000035437488,0.30430886,0.00010116694,0.0013903971,0.00049146655],"study_design_scores_gemma":[0.00048029365,0.000111063986,0.9718991,0.00011502864,0.000020594423,0.00029235927,0.00021268147,0.00002584107,0.02240285,0.0006118371,0.003730515,0.0000978128],"about_ca_topic_score_codex":0.0001936057,"about_ca_topic_score_gemma":0.000005052887,"teacher_disagreement_score":0.281906,"about_ca_system_score_codex":0.000034813063,"about_ca_system_score_gemma":0.00009915354,"threshold_uncertainty_score":0.3013346},"labels":[],"label_agreement":null},{"id":"W2921528384","doi":"10.1111/tra.12640","title":"TRAPPC11 functions in autophagy by recruiting ATG2B‐WIPI4/WDR45 to preautophagosomal membranes","year":2019,"lang":"en","type":"article","venue":"Traffic","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Institute for Research in Immunology and Cancer; Université de Montréal; Concordia University","funders":"European Regional Development Fund; Instituto de Salud Carlos III; Christian-Albrechts-Universität zu Kiel; Canadian Institutes of Health Research; Institute of Genetics; Concordia University; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Biology; Cell biology; Membrane; Autophagy; Autophagosome; Phenocopy; Membrane protein; Mutant; Biochemistry","score_opus":0.010561831530931138,"score_gpt":0.2661866377336898,"score_spread":0.2556248062027586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921528384","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98925865,0.0016156116,0.000016924623,0.000638798,0.00041431907,0.0010672907,0.00002565208,0.00034262333,0.0066201543],"genre_scores_gemma":[0.9861623,0.000046969166,0.000117504926,0.0011818378,0.0001943301,0.000109549066,0.000077365185,0.000057958365,0.012052156],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9982178,0.000060374994,0.0003952822,0.0004982583,0.00031790783,0.0005103333],"domain_scores_gemma":[0.99903065,0.000115050476,0.00006216351,0.00045182966,0.000043758762,0.0002965239],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00016902189,0.0002626159,0.00044534705,0.00022311251,0.00007046058,0.000028396948,0.0001551239,0.00015750273,0.0020235036],"category_scores_gemma":[0.00004275252,0.00024581022,0.00016112541,0.00049987616,0.000038674494,0.00013798798,0.000023456352,0.00027809627,0.0014297409],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0055698305,0.0072708074,0.01963259,0.0020207793,0.0011478923,0.0010926025,0.024311073,0.012656872,0.51850784,0.0011136611,0.043907512,0.36276856],"study_design_scores_gemma":[0.049352724,0.0072962516,0.35517564,0.0023762465,0.00093613303,0.00076819473,0.009294952,0.027487256,0.19631548,0.0002753266,0.3463524,0.0043693706],"about_ca_topic_score_codex":0.00003479444,"about_ca_topic_score_gemma":0.000018519382,"teacher_disagreement_score":0.35839918,"about_ca_system_score_codex":0.00009920831,"about_ca_system_score_gemma":0.00012845066,"threshold_uncertainty_score":0.9999994},"labels":[],"label_agreement":null},{"id":"W2921720200","doi":"10.1080/15548627.2019.1586321","title":"Regulation of the proline regulatory axis and autophagy modulates stemness in TP73/p73 deficient cancer stem-like cells","year":2019,"lang":"en","type":"letter","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Cancer stem cell; Cell biology; Cancer research; Cancer cell; Cancer; PI3K/AKT/mTOR pathway; Population; Stem cell; Signal transduction; Genetics; Apoptosis","score_opus":0.012928235027076755,"score_gpt":0.24500047449380546,"score_spread":0.2320722394667287,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921720200","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9500928,0.014002362,0.000019161484,0.030202454,0.0021804722,0.0027861677,0.00018904412,0.000108205066,0.00041935086],"genre_scores_gemma":[0.8797504,0.00046266118,0.000054413522,0.08971491,0.0010709171,0.00021144109,0.00020457162,0.00017942772,0.02835129],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.99627405,0.0002623062,0.0009922296,0.000914624,0.00093420537,0.0006225923],"domain_scores_gemma":[0.99732256,0.00016340466,0.00070542103,0.0014952072,0.00022291749,0.00009050577],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003587816,0.000630072,0.0012384265,0.00036380262,0.00009379352,0.000031258496,0.0003993647,0.0010386861,0.00034960228],"category_scores_gemma":[0.0000164244,0.00046037324,0.00033235527,0.0004889642,0.0003758407,0.00012650543,0.00018468151,0.0011415789,0.000027208864],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020078218,0.0021058633,0.021260634,0.0239871,0.003013838,0.0012785876,0.005749655,0.0065403255,0.27049053,0.0012123096,0.62232554,0.040027816],"study_design_scores_gemma":[0.007809235,0.000488877,0.5151336,0.0042254934,0.0010816102,0.00012930292,0.00009400325,0.008614157,0.22158432,0.0009815285,0.23836648,0.0014913549],"about_ca_topic_score_codex":0.0002699094,"about_ca_topic_score_gemma":0.00001878495,"teacher_disagreement_score":0.493873,"about_ca_system_score_codex":0.00031486017,"about_ca_system_score_gemma":0.0006132884,"threshold_uncertainty_score":0.9997848},"labels":[],"label_agreement":null},{"id":"W2922113267","doi":"10.1158/1078-0432.ccr-18-3791","title":"HERC3-Mediated SMAD7 Ubiquitination Degradation Promotes Autophagy-Induced EMT and Chemoresistance in Glioblastoma","year":2019,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":150,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation","funders":"National Natural Science Foundation of China","keywords":"Autophagy; Cancer research; Downregulation and upregulation; U87; Biology; Temozolomide; Glioma; Epithelial–mesenchymal transition; Brain tumor; Pathology; Medicine; Apoptosis; Gene","score_opus":0.12349272573939302,"score_gpt":0.4866531611964809,"score_spread":0.36316043545708787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922113267","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944245,0.0012669653,0.0000033395563,0.002197109,0.00015585046,0.0010449536,0.000008340591,0.00005771884,0.0008411856],"genre_scores_gemma":[0.99674094,0.0007062427,0.000045224948,0.0003817608,0.00023495522,0.00015327713,0.000021897347,0.0000304515,0.0016852367],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9975367,0.0003312957,0.00051561295,0.0005295098,0.00065582985,0.00043100351],"domain_scores_gemma":[0.99822974,0.00074989034,0.00008806069,0.00035689003,0.0003271169,0.00024829485],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0020785672,0.00013657217,0.00038032007,0.00021859474,0.00006673844,0.000037248366,0.00013890002,0.00022974808,0.0006055223],"category_scores_gemma":[0.0009920334,0.00011912439,0.0000710422,0.00056281657,0.00018037147,0.0001468668,0.000071038776,0.0007744388,0.00014986703],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013690856,0.0027211034,0.59683317,0.001478748,0.00027387842,0.00039848013,0.0010405027,0.0000036885376,0.16015819,0.0020094602,0.0028836958,0.21850823],"study_design_scores_gemma":[0.006406931,0.0015850225,0.9266144,0.0004907203,0.000019873884,0.0000053866934,0.00015331236,0.0018554004,0.060146566,0.0012282161,0.001292988,0.000201185],"about_ca_topic_score_codex":0.00014813326,"about_ca_topic_score_gemma":0.00019125173,"teacher_disagreement_score":0.32978123,"about_ca_system_score_codex":0.00020127925,"about_ca_system_score_gemma":0.0005162485,"threshold_uncertainty_score":0.66300446},"labels":[],"label_agreement":null},{"id":"W2922171655","doi":"10.1016/j.redox.2019.101181","title":"Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress","year":2019,"lang":"en","type":"article","venue":"Redox Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Deutsche Forschungsgemeinschaft; Foundation Fighting Blindness","keywords":"Autophagy; Proteostasis; BAG3; Cell biology; Downregulation and upregulation; Biology; Unfolded protein response; Oxidative stress; Lysosome; Chemistry; Endoplasmic reticulum; Biochemistry; Apoptosis","score_opus":0.0068011448189922,"score_gpt":0.26986451786590526,"score_spread":0.2630633730469131,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922171655","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969402,0.00042958243,0.0001719408,0.00014703734,0.00016986254,0.0011070211,0.00030649372,0.000078657045,0.0006492125],"genre_scores_gemma":[0.9985337,0.00010497261,0.00015438374,0.00046442947,0.000099160265,0.00005502704,0.00005917376,0.000034999903,0.0004941272],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976058,0.00075101905,0.00030361582,0.0006717563,0.00019867317,0.00046915788],"domain_scores_gemma":[0.99795514,0.00093291205,0.00021600752,0.0003891669,0.00019902473,0.00030772845],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003180296,0.00031859643,0.00072281767,0.00023378147,0.000056625984,0.0000074171357,0.00016432423,0.00027792642,0.00054211216],"category_scores_gemma":[0.0002620807,0.00027733785,0.00012041582,0.0003569723,0.00025685446,0.000083153645,0.00012523572,0.00031206422,0.00018665833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02038212,0.00031675003,0.0010111369,0.000041861476,0.0003211924,0.000041049374,0.00041806215,0.00000939985,0.9747817,0.00027270083,0.000031796626,0.0023722292],"study_design_scores_gemma":[0.0030201704,0.0059682233,0.17879705,0.00006244816,0.00006442542,0.0000175958,0.000064924105,0.00030259954,0.81124216,0.00011555851,0.00014757703,0.0001972849],"about_ca_topic_score_codex":0.00021188594,"about_ca_topic_score_gemma":0.000012967356,"teacher_disagreement_score":0.1777859,"about_ca_system_score_codex":0.00019161015,"about_ca_system_score_gemma":0.0007097983,"threshold_uncertainty_score":0.9999679},"labels":[],"label_agreement":null},{"id":"W2922255565","doi":"10.1038/s41598-019-41111-6","title":"Iron induces insulin resistance in cardiomyocytes via regulation of oxidative stress","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; York University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Protein kinase B; Reactive oxygen species; Chemistry; Oxidative stress; Insulin resistance; Mitochondrial ROS; Internal medicine; NADPH oxidase; Cell biology; Endocrinology; Insulin; Phosphorylation; Biology; Biochemistry; Apoptosis; Medicine","score_opus":0.009795102844573121,"score_gpt":0.2584693807673571,"score_spread":0.24867427792278396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922255565","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99277824,0.0010921127,0.000023048091,0.000050381062,0.0011332015,0.00040895116,0.0000030238555,0.000020144967,0.004490887],"genre_scores_gemma":[0.9956155,0.0000083277955,0.00030541472,0.00001177704,0.000031751115,0.000009335794,0.00006754584,0.000008712885,0.003941637],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859804,0.000038781087,0.0003937762,0.00040044994,0.00042742302,0.00014152405],"domain_scores_gemma":[0.99887955,0.000023750386,0.0002756159,0.0006284852,0.0001373532,0.00005521849],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055139547,0.000086663866,0.00024014895,0.00018928977,0.000035013767,0.000019446985,0.00005089414,0.00006029393,0.00018968247],"category_scores_gemma":[0.000060129907,0.00007482387,0.00006562864,0.0004557342,0.00012588836,0.00013965233,0.000021604492,0.00007481155,0.000015313115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026176998,0.00029733355,0.13860993,0.00027560128,0.00005218295,0.00028299182,0.0018982972,0.00015995612,0.85415137,0.00026788964,0.00080230006,0.0029403626],"study_design_scores_gemma":[0.00046301924,0.00004001399,0.3918811,0.00028629316,0.000021198515,0.000014080176,0.00015854072,0.000037181773,0.5989964,0.0066844365,0.0013217193,0.0000960128],"about_ca_topic_score_codex":0.000028936805,"about_ca_topic_score_gemma":0.000022785049,"teacher_disagreement_score":0.255155,"about_ca_system_score_codex":0.000052726635,"about_ca_system_score_gemma":0.00013795136,"threshold_uncertainty_score":0.30512288},"labels":[],"label_agreement":null},{"id":"W2922391060","doi":"10.2174/1389203720666190305165203","title":"Role of Autophagy in Chronic Liver Inflammation and Fibrosis","year":2019,"lang":"en","type":"review","venue":"Current Protein and Peptide Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Autophagy; Hepatology; Inflammation; Fibrosis; Glycogenolysis; Biology; Liver fibrosis; Medicine; Metabolism; Internal medicine; Biochemistry","score_opus":0.041519398853958556,"score_gpt":0.34954831439989453,"score_spread":0.308028915545936,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922391060","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.020385487,0.97782874,0.0000036544652,0.000004407119,0.000054141226,0.0015021858,0.000011364838,0.000011955367,0.0001980732],"genre_scores_gemma":[0.005820403,0.9937731,0.0000720493,0.0000021112255,0.00008972024,0.00008876996,0.000013788369,0.000010531951,0.0001295213],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99873155,0.000042232194,0.00035194147,0.00038712585,0.00027475032,0.000212426],"domain_scores_gemma":[0.9993266,0.000029498224,0.00021741878,0.0002629523,0.000048552276,0.000114962284],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000345001,0.00019532983,0.0006782286,0.00029877992,0.000047268124,0.000029433759,0.00014139639,0.00008733013,0.000050603925],"category_scores_gemma":[0.00004842172,0.00014742158,0.00008576213,0.00042155356,0.0003826821,0.00019258678,0.00009874793,0.00021526348,0.00001792461],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006707002,0.000019611492,0.00001863229,0.017998712,0.000007200102,0.0000014266458,0.00009630789,1.622531e-7,0.00143218,0.00046261543,0.0000030728158,0.97995335],"study_design_scores_gemma":[0.001086074,0.00050182815,0.0031330371,0.07990644,0.0003316836,0.00003667772,0.000023828123,0.0007119131,0.0039764256,0.00041102734,0.9093944,0.00048670988],"about_ca_topic_score_codex":0.000014672688,"about_ca_topic_score_gemma":0.0000022716827,"teacher_disagreement_score":0.9794667,"about_ca_system_score_codex":0.00012199852,"about_ca_system_score_gemma":0.0009809985,"threshold_uncertainty_score":0.6011678},"labels":[],"label_agreement":null},{"id":"W2923997129","doi":"10.1093/ibd/izz039","title":"The Inflammatory Bowel Disease Drug Azathioprine Induces Autophagy via mTORC1 and the Unfolded Protein Response Sensor PERK","year":2019,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Crohn's and Colitis UK; Hospital for Sick Children; Hebrew University of Jerusalem; Edinburgh Napier University","keywords":"Autophagy; ATG16L1; Azathioprine; mTORC1; PI3K/AKT/mTOR pathway; ATG5; Biology; Cancer research; Medicine; Signal transduction; Cell biology; Apoptosis; Disease; Pathology","score_opus":0.005359494841335297,"score_gpt":0.23047199102573906,"score_spread":0.22511249618440377,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2923997129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9810831,0.010659365,0.000008524689,0.003168921,0.00039946777,0.003805905,0.000084405954,0.00045070288,0.00033963347],"genre_scores_gemma":[0.99028414,0.0004167907,0.000023705035,0.0014389447,0.0005424814,0.00074337196,0.000032076878,0.00013238442,0.006386117],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9953291,0.0010551834,0.00089079473,0.000818788,0.0010717524,0.00083438103],"domain_scores_gemma":[0.9953333,0.0010497787,0.00042131604,0.0018672139,0.00025722277,0.0010711702],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011624965,0.0007097236,0.00061074406,0.0001874687,0.0008755705,0.00026234158,0.0005998266,0.00016956613,0.00036645838],"category_scores_gemma":[0.00065831695,0.0004227107,0.0005102131,0.00021723873,0.0013459015,0.0004172022,0.00030645047,0.00055442954,0.00046764422],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.34576756,0.0024459609,0.49182692,0.0047462517,0.0044686846,0.009318836,0.008295734,0.0004049117,0.07173143,0.03680277,0.007668472,0.01652248],"study_design_scores_gemma":[0.011038346,0.00014669122,0.9598208,0.00048967847,0.0005771327,0.000046519683,0.00077527214,0.0010217923,0.0024638346,0.0031042797,0.019770741,0.00074489013],"about_ca_topic_score_codex":0.000020036377,"about_ca_topic_score_gemma":0.000005995709,"teacher_disagreement_score":0.4679939,"about_ca_system_score_codex":0.0001484607,"about_ca_system_score_gemma":0.0010186348,"threshold_uncertainty_score":0.9998225},"labels":[],"label_agreement":null},{"id":"W2924078657","doi":"10.1113/jp277821","title":"The role of autophagy and lipid catabolism in enhancing cold stress resistance in zebrafish","year":2019,"lang":"en","type":"letter","venue":"The Journal of Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Autophagy; Zebrafish; Catabolism; Cell biology; Cold stress; Stress (linguistics); Lipid metabolism; Chemistry; Biology; Biochemistry; Metabolism; Gene","score_opus":0.00522591692092635,"score_gpt":0.2392801211523551,"score_spread":0.23405420423142875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2924078657","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.929582,0.029355794,0.0000015215871,0.040067337,0.00043152226,0.0002880283,0.000022228121,0.0000034455857,0.00024811274],"genre_scores_gemma":[0.9350688,0.004630623,0.000018729803,0.05695116,0.002644696,0.0000058518126,0.000012724988,0.000037242222,0.00063015916],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983481,0.00039700518,0.00062762806,0.00012890217,0.0002178756,0.0002804926],"domain_scores_gemma":[0.9979352,0.00085026515,0.00070872187,0.00037920265,0.00009784753,0.000028789142],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051231415,0.00017913687,0.0007459224,0.00013952404,0.000038293416,0.000005601041,0.00035067397,0.00028066186,0.000025135809],"category_scores_gemma":[0.000079953206,0.00009774805,0.00010245117,0.000121005345,0.00021597759,0.00004700689,0.000057122306,0.0015266323,0.0000026927537],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029212348,0.0001910663,0.00055231206,0.0006604551,0.00042468176,0.00022318508,0.002915836,0.00003670579,0.91467094,0.0003938106,0.07637293,0.0006368208],"study_design_scores_gemma":[0.007540914,0.0010016768,0.20609486,0.0038875334,0.0004910431,0.00015625126,0.0011244299,0.00005774389,0.20869432,0.014648833,0.55578685,0.0005155391],"about_ca_topic_score_codex":0.00006328275,"about_ca_topic_score_gemma":0.0001216143,"teacher_disagreement_score":0.70597667,"about_ca_system_score_codex":0.000050945942,"about_ca_system_score_gemma":0.00023466014,"threshold_uncertainty_score":0.66325426},"labels":[],"label_agreement":null},{"id":"W2934039904","doi":"10.3390/cells8040290","title":"Hepatitis C Virus Non-Structural Protein 5A (NS5A) Disrupts Mitochondrial Dynamics and Induces Mitophagy","year":2019,"lang":"en","type":"article","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"Ministry of Science and Technology, Taiwan","keywords":"Mitophagy; NS5A; Autophagy; Cell biology; Parkin; Mitochondrion; Biology; Hepatitis C virus; Biochemistry; Virology; Virus; Hepacivirus; Apoptosis","score_opus":0.0045506274831241915,"score_gpt":0.2387214493133327,"score_spread":0.23417082183020851,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2934039904","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99607956,0.0004438017,0.000029624678,0.00011268395,0.0010035178,0.0009418243,0.000051601965,0.00004915782,0.0012882516],"genre_scores_gemma":[0.99406165,0.0001457702,0.00050924596,0.0002868595,0.00047067192,0.000029095236,0.000056954348,0.00003386887,0.0044058696],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895674,0.000027268332,0.00020334488,0.00032317464,0.00022142589,0.000268048],"domain_scores_gemma":[0.99933594,0.000028387016,0.00007998641,0.0003262091,0.000042646734,0.00018681213],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000033100863,0.00019864463,0.00031127606,0.000063206375,0.00006173835,0.00003694154,0.00009819677,0.00014751247,0.00070268667],"category_scores_gemma":[0.000010149963,0.0001656856,0.00008798507,0.00009585893,0.00008333607,0.00011227359,0.000047189358,0.00018923031,0.00023035068],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040722845,0.00009313208,0.017162172,0.00020523768,0.00013686651,0.00016409147,0.00047442855,0.0000024235028,0.9689963,0.00032664367,0.00051279407,0.011518711],"study_design_scores_gemma":[0.0043984368,0.00065780606,0.12770341,0.00019804187,0.00009334508,0.000047219382,0.00009390027,0.0031831686,0.8613665,0.00088521803,0.00093139673,0.00044155313],"about_ca_topic_score_codex":0.00029952123,"about_ca_topic_score_gemma":0.000055860968,"teacher_disagreement_score":0.11054124,"about_ca_system_score_codex":0.00005556069,"about_ca_system_score_gemma":0.000072730356,"threshold_uncertainty_score":0.7693926},"labels":[],"label_agreement":null},{"id":"W2935205376","doi":"10.1634/theoncologist.2018-0621","title":"Pantoprazole Affecting Docetaxel Resistance Pathways via Autophagy (PANDORA): Phase II Trial of High Dose Pantoprazole (Autophagy Inhibitor) with Docetaxel in Metastatic Castration-Resistant Prostate Cancer (mCRPC)","year":2019,"lang":"en","type":"article","venue":"The Oncologist","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Docetaxel; Pantoprazole; Autophagy; Medicine; Prostate cancer; Oncology; Internal medicine; Cancer; Pharmacology; Cancer research; Chemistry; Apoptosis","score_opus":0.024193007141688032,"score_gpt":0.3156571043337689,"score_spread":0.2914640971920809,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2935205376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901659,0.0026062867,0.000049688446,0.0007808649,0.0005720719,0.004199252,0.00020183736,0.00014120451,0.0012828872],"genre_scores_gemma":[0.99564296,0.00035958373,0.00056819204,0.0003483596,0.0002975969,0.0005307232,0.000079379126,0.00007712468,0.002096091],"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9960555,0.00039367224,0.0011693753,0.0007471235,0.00083277794,0.0008015483],"domain_scores_gemma":[0.9971144,0.0004658606,0.0009784586,0.0009870416,0.0002369857,0.00021720449],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013021872,0.00056214613,0.0013523499,0.00021350116,0.00031993224,0.000058639078,0.00038401873,0.00017229731,0.00038177488],"category_scores_gemma":[0.00013898268,0.00036150182,0.00023213937,0.0007834602,0.00051117304,0.00031439724,0.00011435623,0.0006156666,0.000030340774],"study_design_candidate":"randomized_trial","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.4204403,0.014523632,0.0014752959,0.0015656832,0.0014889009,0.0021496785,0.0082465345,0.0015228054,0.5131842,0.0034384218,0.00071413256,0.031250425],"study_design_scores_gemma":[0.5406058,0.028547399,0.031209037,0.0018432039,0.001757711,0.00015735482,0.003141411,0.0014305593,0.38243693,0.0031609656,0.00409922,0.0016104083],"about_ca_topic_score_codex":0.0016713061,"about_ca_topic_score_gemma":0.0018828522,"teacher_disagreement_score":0.13074727,"about_ca_system_score_codex":0.00043904668,"about_ca_system_score_gemma":0.0011713081,"threshold_uncertainty_score":0.9998837},"labels":[],"label_agreement":null},{"id":"W2937057550","doi":"10.1016/j.celrep.2019.03.037","title":"Autophagy Regulation of Metabolism Is Required for CD8+ T Cell Anti-tumor Immunity","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":182,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; University of Victoria","funders":"Genentech; National Cancer Institute; BC Cancer Foundation; Canadian Cancer Society; Howard Hughes Medical Institute","keywords":"Autophagy; Immunity; Cell metabolism; Cell biology; Metabolism; CD8; Biology; Immune system; Immunology; Biochemistry; Apoptosis","score_opus":0.01292071057011717,"score_gpt":0.26374953341700974,"score_spread":0.25082882284689256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2937057550","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98491126,0.0018991511,0.00021041479,0.00005292439,0.0006000641,0.00094416377,0.0000109741895,0.00006089622,0.011310132],"genre_scores_gemma":[0.9885642,0.00004452912,0.00059919746,0.00032378125,0.000121606594,0.000024263465,0.00007591485,0.00003819879,0.010208337],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985968,0.00002978683,0.0005705022,0.00030669093,0.00027053404,0.0002257061],"domain_scores_gemma":[0.9982074,0.00004669291,0.00053702027,0.0008926021,0.00020309967,0.00011319281],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031775772,0.00016353157,0.00047848836,0.00009481742,0.000050811675,0.000008601888,0.00006719603,0.00010007438,0.00082436024],"category_scores_gemma":[0.00003586856,0.00014559607,0.0002598964,0.00013961465,0.00004612137,0.00010518667,0.00002925948,0.000092055874,0.00003277107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017603268,0.00039503898,0.0036873715,0.0004570501,0.0000644451,0.00010848529,0.0003446327,0.000017044009,0.9919498,0.000121644334,0.0021012814,0.0005771565],"study_design_scores_gemma":[0.0013453243,0.0001331358,0.0662544,0.000048257752,0.00018303333,0.00006145587,0.000055786513,0.00028127414,0.91734636,0.0014535597,0.01270107,0.00013632188],"about_ca_topic_score_codex":0.000033863005,"about_ca_topic_score_gemma":1.7461248e-7,"teacher_disagreement_score":0.07460344,"about_ca_system_score_codex":0.000027349895,"about_ca_system_score_gemma":0.00019244799,"threshold_uncertainty_score":0.9026167},"labels":[],"label_agreement":null},{"id":"W2937494202","doi":"10.1101/604884","title":"Neutrophils use selective autophagy receptor p62/SQSTM1 to target <i>Staphylococcus aureus</i> for degradation <i>in vivo</i> in zebrafish","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council","keywords":"Staphylococcus aureus; Autophagy; Intracellular; Intracellular parasite; Phagosome; Phagocytosis; Microbiology; Biology; Zebrafish; In vivo; Pathogen; Cell biology; Bacteria; Apoptosis; Biochemistry","score_opus":0.013809651391396997,"score_gpt":0.24194201250966152,"score_spread":0.22813236111826452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2937494202","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98680246,0.0011382136,0.0017371776,0.00066767953,0.0015601744,0.0064207027,0.001278143,0.0003750258,0.00002043268],"genre_scores_gemma":[0.9835236,0.00023488908,0.009791608,0.003415391,0.0007663962,0.001862357,0.000009056483,0.0003214817,0.00007523281],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9952608,0.00021527514,0.0010572831,0.0018075182,0.0005540452,0.0011050852],"domain_scores_gemma":[0.9964166,0.0002355428,0.00047839683,0.0016330105,0.00068232376,0.0005541118],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006784919,0.00093738147,0.0014301446,0.0009823394,0.000098580305,0.00018556407,0.00054583995,0.000948611,0.00010783755],"category_scores_gemma":[0.00047030614,0.0010293161,0.0003751598,0.001255438,0.000077480174,0.00036162822,0.00026125798,0.0011163253,0.00009215393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013049681,0.00089944823,0.017792204,0.00080279715,0.00029061473,0.00015555647,0.000057514062,0.00087144517,0.9706095,0.0004428077,0.006769671,0.0000034891104],"study_design_scores_gemma":[0.0046786834,0.00044353367,0.14393215,0.0010991704,0.00017870056,3.8248714e-8,0.0000067692754,0.00077852036,0.81994104,0.000018223329,0.027650522,0.0012726281],"about_ca_topic_score_codex":0.00016942322,"about_ca_topic_score_gemma":0.00001849825,"teacher_disagreement_score":0.15066841,"about_ca_system_score_codex":0.0011325858,"about_ca_system_score_gemma":0.0015812891,"threshold_uncertainty_score":0.9992157},"labels":[],"label_agreement":null},{"id":"W2938010226","doi":"10.1080/23723556.2019.1600350","title":"USP30: protector of peroxisomes and mitochondria","year":2019,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Mitophagy; Peroxisome; Deubiquitinating enzyme; Ubiquitin ligase; Ubiquitin; Mitochondrion; Autophagy; Cell biology; Biology; Biochemistry; Microbody; Chemistry; Gene; Apoptosis","score_opus":0.004853397485460807,"score_gpt":0.2586196387858667,"score_spread":0.25376624130040587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2938010226","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910867,0.0036584828,0.0006518045,0.00040163193,0.00016433187,0.0008163942,0.000003434756,0.000030272518,0.0031869214],"genre_scores_gemma":[0.9965808,0.00005582504,0.0015128053,0.0005877743,0.000048079288,0.000034292818,0.000015692114,0.000027494732,0.001137269],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990787,0.00008122508,0.00021457973,0.00026276064,0.0001603257,0.00020242525],"domain_scores_gemma":[0.9993496,0.000029893135,0.00009078766,0.0003467988,0.00006180248,0.000121127734],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009251637,0.00013526135,0.00040927602,0.00008779584,0.000019997593,0.0000043792334,0.00007694958,0.00017404814,0.00061552884],"category_scores_gemma":[0.000026694803,0.000118233314,0.000116978656,0.00009759913,0.000109707325,0.000025395584,0.00004636854,0.00014880025,0.00009035599],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019688926,0.00020392278,0.0029927487,0.000121849196,0.00013406042,0.00029703067,0.00017530206,0.000001930209,0.9924412,0.0007123398,0.00007262649,0.002650117],"study_design_scores_gemma":[0.00280993,0.0013148285,0.003966179,0.00003971953,0.00011554181,0.00006724565,0.00008098078,0.00009775943,0.9725835,0.0004521566,0.01834571,0.00012648528],"about_ca_topic_score_codex":0.000015244976,"about_ca_topic_score_gemma":8.243004e-7,"teacher_disagreement_score":0.01985772,"about_ca_system_score_codex":0.00003911744,"about_ca_system_score_gemma":0.00015259767,"threshold_uncertainty_score":0.6739609},"labels":[],"label_agreement":null},{"id":"W2939482774","doi":"10.1080/21505594.2019.1605803","title":"The roles of apoptosis, autophagy and unfolded protein response in arbovirus, influenza virus, and HIV infections","year":2019,"lang":"en","type":"review","venue":"Virulence","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":245,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Assiniboine Community College; CancerCare Manitoba; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"","keywords":"Unfolded protein response; Biology; Autophagy; Cell biology; Virology; Endoplasmic reticulum; Apoptosis","score_opus":0.03357225005789052,"score_gpt":0.3463665985697709,"score_spread":0.3127943485118804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2939482774","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13973191,0.8584112,0.000004062558,0.00003539968,0.000053362073,0.0015877491,0.00006848516,0.000034127126,0.000073688185],"genre_scores_gemma":[0.0048198695,0.99432766,0.000034626017,0.00012271009,0.00004423456,0.00030529016,0.000008231617,0.00004273736,0.00029464514],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979717,0.00041779407,0.0006732456,0.00041867077,0.00023924025,0.0002793626],"domain_scores_gemma":[0.9982348,0.00059695105,0.00036063226,0.0006344754,0.000048319933,0.00012479787],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000663681,0.00036457393,0.0011678737,0.0002863492,0.00010682548,0.000036074878,0.00018097459,0.0002898879,0.00002108985],"category_scores_gemma":[0.00033609953,0.00024078405,0.00016900858,0.00040389807,0.0003175916,0.00009782807,0.00011612136,0.00045273767,0.000036350477],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017666543,0.00041466978,0.0003891686,0.017130924,0.0004828398,0.00003335314,0.0004421288,0.0000013859801,0.0021429928,0.001502899,0.000112782145,0.9755802],"study_design_scores_gemma":[0.0014471442,0.0005811418,0.0020391326,0.023227885,0.00072971726,0.00005617726,0.000046622805,0.000026082067,0.0015110434,0.00039404823,0.96950126,0.00043972526],"about_ca_topic_score_codex":0.00004158546,"about_ca_topic_score_gemma":0.000016091128,"teacher_disagreement_score":0.97514045,"about_ca_system_score_codex":0.00006593342,"about_ca_system_score_gemma":0.0005228663,"threshold_uncertainty_score":0.9818889},"labels":[],"label_agreement":null},{"id":"W2939742915","doi":"10.1007/s00018-019-03074-9","title":"NEAT1 regulates neuroglial cell mediating Aβ clearance via the epigenetic regulation of endocytosis-related genes expression","year":2019,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":138,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre","funders":"Shenzhen Municipal Science and Technology Innovation Council; Postdoctoral Research Foundation of China; National Natural Science Foundation of China","keywords":"Endocytosis; Cell biology; Epigenetics; Cell; Gene expression; Gene; Regulation of gene expression; Biology; Intracellular; Chemistry; Genetics","score_opus":0.0070433536978143285,"score_gpt":0.22670468462112595,"score_spread":0.2196613309233116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2939742915","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9825415,0.015354951,0.00057550153,0.00021470462,0.00023487181,0.00038568405,0.0000015362031,0.000024265903,0.00066695595],"genre_scores_gemma":[0.99883395,0.0003445065,0.00030954322,0.00025595227,0.00005227173,0.0000064321375,0.0000073797146,0.000013645429,0.00017629117],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99866027,0.00011601632,0.00027633348,0.00032734426,0.00040937177,0.00021065284],"domain_scores_gemma":[0.99931866,0.00006432574,0.00016709945,0.00028435988,0.0000518454,0.0001137213],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028963396,0.000136653,0.00021471383,0.000067621586,0.00017552996,0.000020624055,0.00016494308,0.00007221158,0.0000789021],"category_scores_gemma":[0.00003749774,0.00008992661,0.00009810032,0.00025804408,0.00034786924,0.00007742377,0.00005523616,0.00009225704,0.000011427098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044102057,0.000035725992,0.0022969707,0.000049152986,0.000013098426,0.0000063082657,0.00030385144,0.0005070332,0.9949046,0.00009057942,0.000010236427,0.0017383649],"study_design_scores_gemma":[0.00066124793,0.00022587438,0.009514313,0.000057616,0.000053927834,0.0000066186317,0.0001412757,0.008512023,0.9800877,0.00044665273,0.00019407258,0.00009867948],"about_ca_topic_score_codex":0.000012416636,"about_ca_topic_score_gemma":1.5305714e-7,"teacher_disagreement_score":0.01629245,"about_ca_system_score_codex":0.0000053936105,"about_ca_system_score_gemma":0.000081743754,"threshold_uncertainty_score":0.36671007},"labels":[],"label_agreement":null},{"id":"W2940348995","doi":"10.1080/15548627.2019.1606638","title":"Autophagy and cancer research in Iran","year":2019,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"CancerCare Manitoba; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Manitoba Health Research Council","keywords":"Autophagy; Biology; Cancer; Cell biology; Cancer research; Apoptosis; Biochemistry; Genetics","score_opus":0.06790869119880921,"score_gpt":0.41054777993752223,"score_spread":0.342639088738713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2940348995","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9787355,0.008608937,0.000002328922,0.00086793135,0.0002549066,0.000573453,0.0000061651285,0.00007630511,0.010874481],"genre_scores_gemma":[0.9903473,0.0010081847,0.00007982182,0.00097175915,0.0001648948,0.000076892284,0.000007708351,0.00003530979,0.0073080948],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99833703,0.000101530066,0.00023845602,0.00042717057,0.0003981755,0.000497663],"domain_scores_gemma":[0.99916977,0.00012284998,0.000034148477,0.00042280316,0.000057070312,0.0001933536],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00045792788,0.00015400266,0.000336217,0.00031447143,0.000058415208,0.000024734809,0.00011720178,0.00014058706,0.0019100363],"category_scores_gemma":[0.000023499026,0.00013496961,0.00005892986,0.00046691066,0.00012284346,0.00011576826,0.000072802715,0.00041278466,0.00045227495],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022765547,0.0016827664,0.36733067,0.0012987009,0.00048529648,0.002538007,0.005528432,0.000055150533,0.28709295,0.03015843,0.005061745,0.29649132],"study_design_scores_gemma":[0.0055940384,0.00047108793,0.9064672,0.00032194264,0.00002987161,0.00006433139,0.00024636087,0.00094785227,0.053398024,0.003642293,0.028539613,0.00027739667],"about_ca_topic_score_codex":0.0004552815,"about_ca_topic_score_gemma":0.000025393034,"teacher_disagreement_score":0.5391365,"about_ca_system_score_codex":0.00011098524,"about_ca_system_score_gemma":0.00016186746,"threshold_uncertainty_score":0.99900234},"labels":[],"label_agreement":null},{"id":"W2940436565","doi":"10.1016/j.jcjd.2019.04.005","title":"Effect of Acute Aerobic Exercise and Rapamycin Treatment on Autophagy in Peripheral Blood Mononuclear Cells of Adults With Prediabetes","year":2019,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"College of Education, University of New Mexico; Canadian Diabetes Association","keywords":"Prediabetes; Medicine; Peripheral blood mononuclear cell; Autophagy; Internal medicine; Aerobic exercise; Endocrinology; Immunology; Diabetes mellitus; Type 2 diabetes; Apoptosis; Biology","score_opus":0.0023761924231947046,"score_gpt":0.19619857156789725,"score_spread":0.19382237914470254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2940436565","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959367,0.0033209845,7.6536566e-8,0.000037625614,0.000077975674,0.00047107248,0.000037795082,0.0000035205692,0.00011428164],"genre_scores_gemma":[0.99956733,0.00015295141,0.00007669848,0.00004692257,0.00003515327,0.0000063706693,0.0000043933887,0.000027833621,0.000082334234],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900734,0.00006682463,0.00034034022,0.00014776482,0.00014947876,0.00028824655],"domain_scores_gemma":[0.99896395,0.0001002477,0.00023280311,0.00019867384,0.00007464177,0.00042965697],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015242875,0.00019800548,0.0007342798,0.0003289458,0.000018929235,0.0000094194775,0.00009061587,0.00008082356,0.00015501084],"category_scores_gemma":[0.000010139354,0.00013445197,0.00012790159,0.00014448626,0.0001077369,0.000082896266,0.0000042029897,0.00012872274,0.0000025039535],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022471598,0.00051804486,0.8681141,0.0010890644,0.0019744844,0.0003248224,0.0035503353,0.00023186063,0.09596842,0.000020214331,0.00009377479,0.025867691],"study_design_scores_gemma":[0.014084436,0.027261702,0.1546753,0.0024502035,0.00094525906,0.000008164518,0.00011028481,0.00014441846,0.8001253,0.000016663158,0.00002317572,0.00015506367],"about_ca_topic_score_codex":0.00019678973,"about_ca_topic_score_gemma":0.0001339654,"teacher_disagreement_score":0.7134388,"about_ca_system_score_codex":0.00007866306,"about_ca_system_score_gemma":0.00037784275,"threshold_uncertainty_score":0.5482792},"labels":[],"label_agreement":null},{"id":"W2940740131","doi":"10.1016/j.isci.2019.04.023","title":"Identification of Kinases Responsible for p53-Dependent Autophagy","year":2019,"lang":"en","type":"article","venue":"iScience","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Gilead Sciences (Canada)","funders":"National Cancer Institute; Merck","keywords":"Autophagy; Cell biology; Kinase; Biology; Proteasome; Ubiquitin; DNA damage; Effector; BAG3; Cancer research; Biochemistry; Apoptosis; DNA","score_opus":0.01797804686385308,"score_gpt":0.32040812666983454,"score_spread":0.30243007980598147,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2940740131","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964175,0.0005816616,0.0011777995,0.0002440727,0.00024084437,0.0004242039,0.000013293246,0.000027118947,0.00087347947],"genre_scores_gemma":[0.9919009,0.000021256019,0.00027947707,0.00017831626,0.000029297289,0.000021441898,0.0000033965318,0.0000057177494,0.007560156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992702,0.000012656725,0.00017576113,0.00018854298,0.00022927333,0.00012357719],"domain_scores_gemma":[0.999395,0.00006906828,0.0000869799,0.00030485576,0.00009338281,0.000050673432],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003029329,0.00005175387,0.00011504841,0.00007602542,0.000036757625,0.000010015406,0.00012077273,0.000027435175,0.00015223183],"category_scores_gemma":[0.00010306303,0.000042707277,0.00005583287,0.00016269543,0.00006935309,0.00010261841,0.000016782215,0.00002787993,0.000087042245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018874246,0.00010556136,0.0015806061,0.000056073342,0.000007997101,0.0000026012783,0.00015757537,0.000022106384,0.9887219,0.004420031,0.00019257907,0.0045442455],"study_design_scores_gemma":[0.0006489903,0.00022653972,0.05467387,0.00003232803,0.000018066106,0.0000065547088,0.00008456328,0.0011400556,0.94023633,0.0017533287,0.0011277052,0.00005165176],"about_ca_topic_score_codex":0.0000060747902,"about_ca_topic_score_gemma":7.1412546e-7,"teacher_disagreement_score":0.053093262,"about_ca_system_score_codex":0.000020832846,"about_ca_system_score_gemma":0.00017886137,"threshold_uncertainty_score":0.17415522},"labels":[],"label_agreement":null},{"id":"W2940996285","doi":"10.1016/j.neulet.2019.04.053","title":"EDTP/MTMR14: A novel target for improved survivorship to prolonged anoxia and cellular protein aggregates","year":2019,"lang":"en","type":"article","venue":"Neuroscience Letters","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Fundamental Research Funds for the Central Universities; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China","keywords":"Downregulation and upregulation; Biology; Cell biology; Hippocampal formation; Phosphatase; Endocrinology; Gene; Genetics; Phosphorylation","score_opus":0.013988047856730693,"score_gpt":0.24725520742398965,"score_spread":0.23326715956725896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2940996285","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9799389,0.00007423694,0.00258228,0.014176321,0.00033992185,0.0027601551,0.000021024018,0.00007645731,0.000030689418],"genre_scores_gemma":[0.9674172,0.0000019775391,0.0018948539,0.029767195,0.000107176405,0.00019455356,0.0000061210417,0.000029710953,0.0005812178],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985425,0.000025334655,0.00016944735,0.00061146263,0.00021054913,0.0004406976],"domain_scores_gemma":[0.99924165,0.000042010794,0.00007121583,0.00036831293,0.000038119597,0.00023867704],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023919501,0.00018272361,0.00023642158,0.000107484484,0.000099858895,0.00005800626,0.00018467748,0.00005302339,0.000017385957],"category_scores_gemma":[0.0001334431,0.00015272573,0.00007029925,0.00025253993,0.00012084849,0.00014338705,0.00004673656,0.00013068832,0.000015056916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002690019,0.000081721315,0.0043523423,0.000069966154,0.0000042472657,0.000009978798,0.00012158755,0.000006364653,0.9944319,0.000049104703,0.00011175404,0.0004920073],"study_design_scores_gemma":[0.0028362076,0.0016237051,0.025867956,0.00009888987,0.000028094624,0.000019498166,0.0000256468,0.0031260364,0.9524189,0.00008782011,0.013510337,0.0003568828],"about_ca_topic_score_codex":0.000020132717,"about_ca_topic_score_gemma":0.0000016027757,"teacher_disagreement_score":0.042012997,"about_ca_system_score_codex":0.000020362295,"about_ca_system_score_gemma":0.00005342609,"threshold_uncertainty_score":0.6227975},"labels":[],"label_agreement":null},{"id":"W2941642916","doi":"10.1186/s12885-019-5288-y","title":"The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma","year":2019,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Cancer Institute; University of Toledo Foundation; McMaster University","keywords":"Glioblastoma; Surgical oncology; Apoptosis; Key (lock); Cancer research; Signal transduction; Programmed cell death; Medicine; Cell biology; Oncology; Biology; Genetics","score_opus":0.012525110356160187,"score_gpt":0.26747465647590657,"score_spread":0.2549495461197464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2941642916","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933969,0.004032649,0.00001948234,0.00012875172,0.00017440219,0.0006286672,0.00001610105,0.000028229659,0.0015748336],"genre_scores_gemma":[0.99794585,0.00015162688,0.00005744848,0.0004972081,0.000112866815,0.00020952632,0.0000046949144,0.000041132946,0.0009796275],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99863714,0.00008232217,0.00030772045,0.0003163161,0.00025767097,0.00039882265],"domain_scores_gemma":[0.9992224,0.00019028994,0.00009488979,0.00034418906,0.000034022334,0.0001142108],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027914948,0.0001928172,0.0003357807,0.000113863745,0.000050333885,0.000024551598,0.00016648335,0.00013272125,0.0003597409],"category_scores_gemma":[0.000023479555,0.00014270576,0.00010440673,0.00031926317,0.000022079445,0.00007512175,0.00003754398,0.00029098397,0.00010671414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017877319,0.00037348992,0.093719944,0.00015500234,0.00008697576,0.000028301774,0.0027163269,0.00069802866,0.8958896,0.000093101124,0.0004491888,0.0040023243],"study_design_scores_gemma":[0.0075656376,0.00045228266,0.055991948,0.000496562,0.00007760931,0.00000328782,0.0010981878,0.0053417855,0.92553264,0.00040502523,0.0026184125,0.00041660047],"about_ca_topic_score_codex":0.001077241,"about_ca_topic_score_gemma":0.0006259244,"teacher_disagreement_score":0.037727993,"about_ca_system_score_codex":0.00024652603,"about_ca_system_score_gemma":0.00038799093,"threshold_uncertainty_score":0.5819372},"labels":[],"label_agreement":null},{"id":"W2942083769","doi":"10.1152/ajpcell.00261.2018","title":"Autophagy, apoptosis, and mitochondria: molecular integration and physiological relevance in skeletal muscle","year":2019,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Autophagy; Biology; Apoptosis; Cell biology; Effector; Mitochondrion; Cellular stress response; Programmed cell death; Skeletal muscle; Model organism; Organism; Neuroscience; Gene; Genetics; Fight-or-flight response; Anatomy","score_opus":0.006145543227234003,"score_gpt":0.25154876227577183,"score_spread":0.24540321904853782,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2942083769","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975148,0.0015634946,0.000033225668,0.0003045293,0.0002075702,0.00025928265,0.0000038800945,0.000017807935,0.0000954389],"genre_scores_gemma":[0.99597913,0.0013770169,0.001101919,0.0012788015,0.00017710998,0.000010374184,0.000013531706,0.000025518195,0.000036607147],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9982569,0.00028022693,0.0005169927,0.00044512955,0.00013813171,0.0003625966],"domain_scores_gemma":[0.99868184,0.00023117488,0.00050929555,0.00028646545,0.000113517686,0.00017773022],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013715039,0.00028286496,0.0010253645,0.00017704374,0.00003763334,0.0000072867883,0.00015192424,0.00013786071,0.00008629347],"category_scores_gemma":[0.00007756839,0.00021201876,0.00017527625,0.00024098354,0.00071222626,0.00013607007,0.00007818367,0.00058260985,0.000018860857],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047944827,0.00031707174,0.00013122743,0.000044888202,0.00007523668,0.000013078363,0.00015334859,0.00006702541,0.99134105,0.00018717031,0.000099608515,0.0070908605],"study_design_scores_gemma":[0.0064167078,0.010650309,0.66634494,0.00021003425,0.00015598655,0.0001500803,0.0010364838,0.0007324212,0.30534348,0.007599605,0.0008390037,0.00052093837],"about_ca_topic_score_codex":0.000024405696,"about_ca_topic_score_gemma":5.6083184e-7,"teacher_disagreement_score":0.68599755,"about_ca_system_score_codex":0.00004310159,"about_ca_system_score_gemma":0.0000870378,"threshold_uncertainty_score":0.8645874},"labels":[],"label_agreement":null},{"id":"W2943874997","doi":"10.1186/s13046-019-1164-5","title":"Glucose-6-phosphate dehydrogenase blockade potentiates tyrosine kinase inhibitor effect on breast cancer cells through autophagy perturbation","year":2019,"lang":"en","type":"article","venue":"Journal of Experimental & Clinical Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":117,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Trent University; Nottingham Trent University","keywords":"Autophagy; Lapatinib; Tyrosine-kinase inhibitor; Cancer cell; Annexin; Cancer research; Endoplasmic reticulum; Pharmacology; Chemistry; Apoptosis; Biology; Cell biology; Cancer; Internal medicine; Medicine; Breast cancer; Biochemistry; Trastuzumab","score_opus":0.05592489900165123,"score_gpt":0.46154276138968087,"score_spread":0.40561786238802966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943874997","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9616409,0.03392019,0.0000024016636,0.0013883845,0.0017770692,0.00088298845,0.000060888513,0.000027105143,0.00030007458],"genre_scores_gemma":[0.99078584,0.0043215593,0.000064668326,0.0012736013,0.0023745017,0.00007662107,0.000009982483,0.000076944416,0.0010162746],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99533087,0.0005920704,0.0011531757,0.00052620773,0.0017273836,0.0006702846],"domain_scores_gemma":[0.99729633,0.0006350131,0.0004419878,0.00046557168,0.00053837063,0.0006226973],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0016713672,0.00033547118,0.0008887175,0.0002037597,0.00017847304,0.00007339035,0.000342012,0.0002588016,0.0042948048],"category_scores_gemma":[0.00009907639,0.00023790295,0.00066625094,0.00042240118,0.000364458,0.00032758317,0.000119358214,0.0013706293,0.00023468806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01889784,0.0030088027,0.009651627,0.00012581846,0.0005933254,0.00058436696,0.0003420115,0.00006849973,0.957433,0.00006637888,0.0033626487,0.00586569],"study_design_scores_gemma":[0.009751884,0.0077878525,0.010374133,0.0009116841,0.00011687335,0.000088503635,0.00019669757,0.00019457577,0.96795416,0.00006888479,0.002332087,0.00022264686],"about_ca_topic_score_codex":0.00024382537,"about_ca_topic_score_gemma":0.0000029564458,"teacher_disagreement_score":0.029598631,"about_ca_system_score_codex":0.0006995794,"about_ca_system_score_gemma":0.00069807284,"threshold_uncertainty_score":0.9966154},"labels":[],"label_agreement":null},{"id":"W2944528098","doi":"10.1126/sciadv.aau8857","title":"Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains","year":2019,"lang":"en","type":"article","venue":"Science Advances","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; H2020 Marie Skłodowska-Curie Actions; Regione Lazio; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Fondazione Telethon; Associazione Italiana per la Ricerca sul Cancro; ZonMw","keywords":"Autophagy; ULK1; Muscular dystrophy; Muscle atrophy; Atrophy; Cell biology; Mutation; Medicine; Biology; Chemistry; Genetics; Kinase; Gene; Protein kinase A","score_opus":0.013792080257172544,"score_gpt":0.30171919179784773,"score_spread":0.2879271115406752,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944528098","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99480253,0.001654975,0.00023190783,0.00066557876,0.0006951541,0.00056845875,0.000007417858,0.0000942237,0.0012797209],"genre_scores_gemma":[0.997084,0.00039131538,0.0005900106,0.0007232042,0.00016886203,0.000029432902,0.00001746885,0.000017117973,0.0009785822],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980277,0.000042319072,0.00031327078,0.00057365996,0.00057934097,0.000463732],"domain_scores_gemma":[0.99919254,0.0000499134,0.00017594834,0.0003857878,0.000085609936,0.00011021979],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034253133,0.00017982507,0.0002726913,0.00020786384,0.00015936351,0.000039392744,0.00024569014,0.000088686626,0.00016931495],"category_scores_gemma":[0.00007321358,0.00015323944,0.00006334844,0.0011474543,0.0004261533,0.0018229819,0.000035356315,0.00020412494,0.00007446127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012904465,0.00015261385,0.00050456886,0.000030926218,0.0000049793684,0.0000051810857,0.000674177,0.0000917276,0.97263825,0.0005073828,0.00006494823,0.025196183],"study_design_scores_gemma":[0.0019168376,0.00043660135,0.042266198,0.0001744793,0.000011931311,0.0000036448937,0.00089391216,0.0002904727,0.9452792,0.0020188366,0.006473367,0.00023452428],"about_ca_topic_score_codex":0.00009114086,"about_ca_topic_score_gemma":0.0000056512167,"teacher_disagreement_score":0.04176163,"about_ca_system_score_codex":0.00020979863,"about_ca_system_score_gemma":0.00032646747,"threshold_uncertainty_score":0.6248923},"labels":[],"label_agreement":null},{"id":"W2945342735","doi":"10.1080/15548627.2019.1618640","title":"Bacterial outer membrane vesicles trigger pre-activation of a xenophagic response via AMPK","year":2019,"lang":"en","type":"letter","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; AMPK; Cell biology; mTORC1; ULK1; Biology; Protein kinase A; AMP-activated protein kinase; PI3K/AKT/mTOR pathway; Kinase; Signal transduction; ATG16L1; BAG3; Biochemistry; Apoptosis","score_opus":0.01529152818537629,"score_gpt":0.268393816084576,"score_spread":0.25310228789919975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2945342735","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87261254,0.0006589637,0.00015884954,0.1214662,0.0019754942,0.0018542358,0.00015820247,0.00024621206,0.00086933235],"genre_scores_gemma":[0.47346914,0.00011016776,0.00031800926,0.4724238,0.011788102,0.00018270983,0.0018996791,0.00037921555,0.039429206],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9968259,0.00032635132,0.0008290767,0.00071922765,0.0007556392,0.0005438404],"domain_scores_gemma":[0.9973416,0.0005051719,0.00061552436,0.0012441284,0.00020730952,0.00008627199],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00035969992,0.0005983673,0.001268338,0.0004680828,0.00005700768,0.00004014671,0.0003305975,0.001188373,0.0034033335],"category_scores_gemma":[0.00014626437,0.00052111223,0.00051538105,0.0002736454,0.00016443843,0.00023192578,0.000076074226,0.0010478992,0.00049112906],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015531721,0.00030626197,0.000023712435,0.0012796702,0.0010039705,0.0013594694,0.0005102394,0.0000038658,0.57433957,0.000019648576,0.4016248,0.0039970656],"study_design_scores_gemma":[0.0046282546,0.00078579853,0.0066716243,0.00040416067,0.0004340117,0.00011652636,0.000004959495,0.00006881632,0.34008867,0.00020537963,0.64610344,0.0004883598],"about_ca_topic_score_codex":0.00006895703,"about_ca_topic_score_gemma":3.142163e-7,"teacher_disagreement_score":0.39914337,"about_ca_system_score_codex":0.00016236928,"about_ca_system_score_gemma":0.00051431276,"threshold_uncertainty_score":0.99972403},"labels":[],"label_agreement":null},{"id":"W2945978665","doi":"10.1038/s41531-019-0080-x","title":"Mitochondria function associated genes contribute to Parkinson’s Disease risk and later age at onset","year":2019,"lang":"en","type":"article","venue":"npj Parkinson s Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":161,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre; McGill Genome Centre; Montreal Neurological Institute and Hospital","funders":"National Institute on Aging; Rosetrees Trust; Parkinson's UK; U.S. Department of Health and Human Services; National Institutes of Health; Medical Research Council; Barts Charity","keywords":"Mendelian randomization; Mitophagy; Biology; Mitochondrion; Proteostasis; Genetics; Disease; Parkinson's disease; Mitochondrial disease; LRRK2; Mitochondrial DNA; Genome-wide association study; Mitochondrial Encephalomyopathies; Bioinformatics; Gene; Mutation; Medicine; Internal medicine; Mitochondrial myopathy; Single-nucleotide polymorphism; Autophagy","score_opus":0.009482790294262867,"score_gpt":0.24737351533190133,"score_spread":0.23789072503763847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2945978665","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.988533,0.0060835583,0.00006320848,0.00082376343,0.00071535725,0.0016778286,0.0015806283,0.00026766208,0.0002549981],"genre_scores_gemma":[0.9867485,0.0008665641,0.00004659168,0.004768813,0.00029570848,0.00021544656,0.00091484527,0.00008798427,0.0060555143],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99711293,0.00024559637,0.00042312682,0.0009314269,0.0006233636,0.0006635827],"domain_scores_gemma":[0.99635637,0.00013676539,0.00020111575,0.00085189595,0.00014271759,0.002311153],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00024014634,0.00046196164,0.00058220717,0.00019131292,0.000250648,0.000089325265,0.00014550425,0.00016188138,0.0015402971],"category_scores_gemma":[0.00028051957,0.0004096556,0.00031695492,0.00027853774,0.000088714114,0.00017098807,0.00013313846,0.00023030893,0.0012663858],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01147574,0.0005735906,0.96893543,0.000108071574,0.0003928159,0.00067023106,0.00011689941,0.000033786968,0.0012473555,0.000030589108,0.013646339,0.0027691259],"study_design_scores_gemma":[0.0039729574,0.00021415735,0.7081953,0.000117102885,0.00080978917,0.0000029465332,0.000015379217,0.00031022183,0.00023840478,0.00032889534,0.28544408,0.00035076542],"about_ca_topic_score_codex":0.00004704447,"about_ca_topic_score_gemma":0.00003408648,"teacher_disagreement_score":0.27179775,"about_ca_system_score_codex":0.00026526858,"about_ca_system_score_gemma":0.000189909,"threshold_uncertainty_score":0.99983555},"labels":[],"label_agreement":null},{"id":"W2946097255","doi":"10.1158/1535-7163.mct-18-1241","title":"17-Hydroxy Wortmannin Restores TRAIL's Response by Ameliorating Increased Beclin 1 Level and Autophagy Function in TRAIL-Resistant Colon Cancer Cells","year":2019,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Center for Advancing Translational Sciences; National Cancer Institute; National Institutes of Health","keywords":"Autophagy; Wortmannin; Cancer; Colorectal cancer; Cancer research; Function (biology); Biology; Medicine; Pharmacology; Internal medicine; Cell biology; PI3K/AKT/mTOR pathway; Apoptosis; Biochemistry; Signal transduction","score_opus":0.026037454798142574,"score_gpt":0.3021730784373269,"score_spread":0.2761356236391843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2946097255","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97159994,0.025662087,0.00026345332,0.0009823861,0.0002461898,0.00085839815,0.00016826202,0.00007897604,0.00014029158],"genre_scores_gemma":[0.98936,0.0010013381,0.00018097955,0.0074285525,0.000072655595,0.0001959282,0.00004204887,0.000093745315,0.0016247507],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977199,0.00031365402,0.00046500078,0.0005774987,0.0004495529,0.00047440222],"domain_scores_gemma":[0.9989695,0.0001190585,0.00019093986,0.0004386493,0.00008996327,0.00019186581],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043963222,0.00036277133,0.00051994435,0.00019672285,0.000089549256,0.000047866877,0.00013659762,0.00025494272,0.00036886925],"category_scores_gemma":[0.000011800409,0.00034697755,0.00012604141,0.0004110837,0.00012364924,0.000097468095,0.00002989242,0.00038968984,0.000011056578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009563038,0.00020917642,0.003670995,0.00007842351,0.0002991466,0.00012972413,0.0007064066,0.00021271221,0.97498345,0.00003833792,0.00054400513,0.009564573],"study_design_scores_gemma":[0.010886227,0.0013449368,0.11535483,0.00062650524,0.0006027762,0.000009308526,0.0003941158,0.0034082578,0.8106629,0.000227899,0.055659708,0.0008225056],"about_ca_topic_score_codex":0.0011030071,"about_ca_topic_score_gemma":0.00029925696,"teacher_disagreement_score":0.16432053,"about_ca_system_score_codex":0.00034201276,"about_ca_system_score_gemma":0.00047893784,"threshold_uncertainty_score":0.9998982},"labels":[],"label_agreement":null},{"id":"W2946460667","doi":"10.3390/cells8050475","title":"ER-Targeted Beclin 1 Supports Autophagosome Biogenesis in the Absence of ULK1 and ULK2 Kinases","year":2019,"lang":"en","type":"article","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Biotechnology and Biological Sciences Research Council; Sigrid Juséliuksen Säätiö; Magnus Ehrnroothin Säätiö; Academy of Finland; Cancer Research UK; Helsingin Yliopisto","keywords":"Autophagy; Autophagosome; Cell biology; ULK1; Endoplasmic reticulum; Kinase; Biogenesis; Biology; BECN1; Autophagy-related protein 13; Chemistry; Biochemistry; Protein kinase A; Apoptosis; Protein phosphorylation","score_opus":0.009109832611255723,"score_gpt":0.25277872903665743,"score_spread":0.2436688964254017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2946460667","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99572897,0.0025855456,0.0000022572754,0.00018257441,0.00012484734,0.00035631083,0.000022668284,0.000016447913,0.0009803869],"genre_scores_gemma":[0.99810874,0.00035983796,0.00005690004,0.00069843425,0.00004167395,0.000008090488,0.000017653338,0.000011593798,0.00069705053],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99923867,0.00004090899,0.00020479978,0.00018173162,0.00017115627,0.0001627604],"domain_scores_gemma":[0.9994031,0.000114814866,0.00006855595,0.0003277307,0.000027162612,0.000058622598],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016699832,0.00010410915,0.0002257641,0.000075856486,0.000017717579,0.0000066422276,0.00009633355,0.00006187194,0.00075706484],"category_scores_gemma":[0.00001362511,0.00006990864,0.00006196891,0.00016698608,0.00007127724,0.000041795345,0.000019375979,0.00006963228,0.0000769953],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029887923,0.000733229,0.21473993,0.00041571492,0.00010430164,0.00041384954,0.0025410098,0.000015287316,0.771853,0.00043967617,0.0017917719,0.0066533186],"study_design_scores_gemma":[0.0012159499,0.00024757287,0.49862278,0.000090812275,0.000039222246,0.000018423236,0.00037156662,0.000108094384,0.4967993,0.00033198393,0.0020348015,0.00011949628],"about_ca_topic_score_codex":0.00006650912,"about_ca_topic_score_gemma":0.000003167042,"teacher_disagreement_score":0.28388286,"about_ca_system_score_codex":0.000009557056,"about_ca_system_score_gemma":0.000058639587,"threshold_uncertainty_score":0.82893294},"labels":[],"label_agreement":null},{"id":"W2947575755","doi":"10.1038/s41419-019-1648-4","title":"Elevated VMP1 expression in acute myeloid leukemia amplifies autophagy and is protective against venetoclax-induced apoptosis","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Cancer Center, University of Colorado; Universitair Medisch Centrum Groningen; ZonMw; University of Alberta","keywords":"Autophagy; Myeloid leukemia; Haematopoiesis; Chemistry; Cell biology; CD34; Apoptosis; Myeloid; Progenitor cell; Leukemia; Cancer research; Stem cell; Biology; Molecular biology; Immunology; Biochemistry","score_opus":0.010982707006233796,"score_gpt":0.2504490690227823,"score_spread":0.2394663620165485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2947575755","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995949,0.0017380548,0.000026504553,0.00006815629,0.00006691875,0.0011197051,0.000040635507,0.00007025996,0.00092081213],"genre_scores_gemma":[0.9971676,0.00057058205,0.000070012364,0.0011747043,0.000050666982,0.00011893602,0.000057953566,0.000031384232,0.00075819116],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987545,0.000048094254,0.00020792498,0.00048533065,0.00018991843,0.00031421217],"domain_scores_gemma":[0.9988354,0.000030143143,0.0000719173,0.00033500692,0.000043392516,0.00068417017],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006398309,0.00024901834,0.00031870237,0.00012628568,0.00008566335,0.0000348516,0.00006747184,0.00012257125,0.00009772982],"category_scores_gemma":[0.000027129789,0.00020778345,0.00007457834,0.00013724057,0.000047037265,0.00013198647,0.000063457876,0.00018226299,0.000037957714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030942739,0.00022130404,0.07305313,0.00048432645,0.000091759815,0.00016793185,0.0012833962,0.000010259663,0.91770035,0.00006569608,0.00023545492,0.0035921142],"study_design_scores_gemma":[0.0058874916,0.000310272,0.44321257,0.0003259434,0.00017787448,0.0000041033236,0.0002716347,0.0015463646,0.54634356,0.0012765859,0.00027429906,0.00036930447],"about_ca_topic_score_codex":0.000038506772,"about_ca_topic_score_gemma":5.076365e-7,"teacher_disagreement_score":0.37135682,"about_ca_system_score_codex":0.00014741065,"about_ca_system_score_gemma":0.0003997057,"threshold_uncertainty_score":0.8473163},"labels":[],"label_agreement":null},{"id":"W2948057470","doi":"10.1172/jci127307","title":"Autophagy is required for lung development and morphogenesis","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Bronchopulmonary dysplasia; Autophagy; Lung; BECN1; Biology; Cell biology; Morphogenesis; AMPK; Respiratory distress; Pathology; Immunology; Medicine; Internal medicine; Apoptosis; Gestational age; Genetics; Pregnancy","score_opus":0.08649733445057324,"score_gpt":0.40042435844838065,"score_spread":0.3139270239978074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2948057470","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995979,0.0007655484,0.0006931904,0.0018137754,0.00039387037,0.00025685434,0.0000017360304,0.000008607044,0.0000874066],"genre_scores_gemma":[0.97329223,0.00014538583,0.020717759,0.0045534507,0.000444797,0.0000046738546,0.0000062656795,0.00001448605,0.000820957],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9985521,0.000043538254,0.0009634956,0.000121039986,0.00022107539,0.00009875229],"domain_scores_gemma":[0.9986043,0.00027131938,0.0005330701,0.00010764688,0.00022968597,0.00025400706],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009785021,0.00008084974,0.0003796246,0.000065454755,0.000032452714,0.000012881965,0.00005063762,0.00011342846,0.00008711081],"category_scores_gemma":[0.0003766257,0.00006151733,0.00015364315,0.0000640378,0.00006122483,0.00013115346,0.000011037442,0.0001198997,0.000009841354],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040179077,0.0006435458,0.7460363,0.0009201669,0.0018161793,0.00008355283,0.0021348428,0.000029975876,0.053251933,0.0021782408,0.022928106,0.16595924],"study_design_scores_gemma":[0.00926351,0.0013230967,0.803623,0.0005209908,0.00040353325,0.00009550655,0.00008901133,0.0045563583,0.151605,0.004291837,0.024026763,0.00020136009],"about_ca_topic_score_codex":6.8423833e-7,"about_ca_topic_score_gemma":1.216003e-7,"teacher_disagreement_score":0.16575788,"about_ca_system_score_codex":0.000026325646,"about_ca_system_score_gemma":0.00041938174,"threshold_uncertainty_score":0.2508604},"labels":[],"label_agreement":null},{"id":"W2948421871","doi":"10.1007/s40263-019-00643-1","title":"Endolysosome and Autolysosome Dysfunction in Alzheimer’s Disease: Where Intracellular and Extracellular Meet","year":2019,"lang":"en","type":"review","venue":"CNS Drugs","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Alzheimer Nederland; ZonMw; EU Joint Programme – Neurodegenerative Disease Research; Weston Brain Institute; Alzheimer's Association","keywords":"Proteostasis; Intracellular; Lysosome; Endosome; Autophagy; Extracellular; Cell biology; Neuroscience; Disease; Biology; Secretion; Medicine; Pathology; Genetics; Biochemistry","score_opus":0.037134919561475375,"score_gpt":0.3097020473000599,"score_spread":0.27256712773858455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2948421871","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0024268215,0.994448,0.000012127631,0.00016494858,0.00038053712,0.0019920927,0.00007636422,0.00011179766,0.0003872854],"genre_scores_gemma":[0.0019462688,0.99478424,0.000051292645,0.00009057022,0.00036555482,0.00017719435,0.00030053602,0.0001428567,0.0021414794],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972195,0.00020139663,0.00074786786,0.00094240526,0.00038267442,0.0005061696],"domain_scores_gemma":[0.9981218,0.00017270853,0.0002987199,0.0008058509,0.000041270196,0.00055965706],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031866017,0.00071172655,0.0021318907,0.00043363584,0.000079214406,0.000068723246,0.00015769576,0.0004844538,0.0003277826],"category_scores_gemma":[0.000036073485,0.000594845,0.00036831727,0.00033463872,0.00018456773,0.00018576822,0.0001148114,0.0005897317,0.00014732778],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001196306,0.0002504617,0.00022816588,0.020973623,0.0007964628,0.00071029353,0.0002691356,5.7780966e-7,0.000025953454,0.0012171369,0.00060585234,0.97480273],"study_design_scores_gemma":[0.0017263887,0.000111800524,0.00029331542,0.012387502,0.0056858067,0.0001326287,0.000051184874,0.00009892493,0.00001110828,0.000253106,0.97861737,0.0006308375],"about_ca_topic_score_codex":0.000020100382,"about_ca_topic_score_gemma":0.0000023198304,"teacher_disagreement_score":0.97801155,"about_ca_system_score_codex":0.00011171699,"about_ca_system_score_gemma":0.0004469259,"threshold_uncertainty_score":0.9996503},"labels":[],"label_agreement":null},{"id":"W2948557789","doi":"10.3389/fcell.2019.00113","title":"The Lysosome Signaling Platform: Adapting With the Times","year":2019,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":165,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Ryerson University","keywords":"Lysosome; Autophagy; Cell biology; mTORC1; ATG16L1; Endocytosis; Cellular adaptation; Biology; TFEB; Organelle; Signal transduction; Cell; Biochemistry; PI3K/AKT/mTOR pathway","score_opus":0.028268701731088527,"score_gpt":0.27661443639933736,"score_spread":0.24834573466824883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2948557789","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007649949,0.99413365,0.00007683099,0.000048885435,0.00034076624,0.0007025177,0.000008669273,0.000016991375,0.003906712],"genre_scores_gemma":[0.00046922753,0.9946304,0.0016515269,0.00023796134,0.0000841632,0.00007114,0.000103984305,0.000028514485,0.0027231153],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99886703,0.00007503946,0.0003250376,0.00031255258,0.0000895686,0.0003307859],"domain_scores_gemma":[0.9993615,0.00023656945,0.00016669052,0.00016135426,0.000013612783,0.000060283735],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026509265,0.00029879322,0.000857332,0.0000876843,0.00020309459,0.000022635042,0.00018999353,0.0002264843,0.00003254455],"category_scores_gemma":[0.000008731086,0.00012364419,0.00010723955,0.00015696119,0.0002357749,0.000027122012,0.0000838779,0.00037730066,0.00003519943],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012478695,0.000027676642,0.00064176007,0.0015238943,0.0004154031,0.000032274085,0.00024821507,2.0135342e-7,0.0000068339905,0.00007631792,0.004644323,0.9922583],"study_design_scores_gemma":[0.00053494604,0.00011384163,0.000027615153,0.0012827043,0.00022530412,0.00007982752,0.0008348185,0.0000064328487,0.000037604073,0.0001210268,0.99652505,0.00021083203],"about_ca_topic_score_codex":0.0000055253527,"about_ca_topic_score_gemma":0.0000016423337,"teacher_disagreement_score":0.9920475,"about_ca_system_score_codex":0.000093949006,"about_ca_system_score_gemma":0.00039662624,"threshold_uncertainty_score":0.50420636},"labels":[],"label_agreement":null},{"id":"W2949137984","doi":"10.15252/embr.201846885","title":"ULK1‐mediated phosphorylation of ATG16L1 promotes xenophagy, but destabilizes the ATG16L1 Crohn's mutant","year":2019,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Cambridge Institute for Medical Research, University of Cambridge; Canadian Institutes of Health Research; UK Dementia Research Institute; Alzheimer’s Research UK; Alzheimer's Society; Medical Research Council; Fondation Roger de Spoelberch; Wellcome; University of Ottawa; Government of Canada; Wellcome Trust","keywords":"ATG16L1; Mutant; ULK1; Phosphorylation; Cell biology; Biology; Chemistry; Autophagy; Genetics; Gene; Protein kinase A; AMPK","score_opus":0.00950908441063975,"score_gpt":0.25079073861492496,"score_spread":0.2412816542042852,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949137984","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99170405,0.0018898005,0.000028764842,0.00032674754,0.00048726634,0.0012770637,0.00001015388,0.00011957895,0.0041565862],"genre_scores_gemma":[0.9976127,0.00010230261,0.00009768455,0.00025105174,0.00012551439,0.00004319766,0.000076426244,0.000044555945,0.0016465385],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980221,0.000062810745,0.0006820339,0.0003986111,0.00053413335,0.0003003056],"domain_scores_gemma":[0.9980234,0.00017231583,0.0004959763,0.000943475,0.00022390831,0.00014094604],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004995036,0.00022698533,0.0004518428,0.000074438205,0.00008046345,0.00001966547,0.00010314317,0.00014388589,0.0015909235],"category_scores_gemma":[0.00029827753,0.00014764734,0.00019787507,0.00028165293,0.00015646958,0.00011632136,0.00004691044,0.0002031394,0.00008453615],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001521007,0.0017523674,0.44045922,0.0007121825,0.0009687687,0.0056629865,0.0037990431,0.000084853804,0.5334397,0.00069399085,0.0017919767,0.0091138715],"study_design_scores_gemma":[0.0013122184,0.00049870746,0.5330637,0.00023133424,0.00023523248,0.0007075925,0.00034611337,0.00039683637,0.45713004,0.0019470592,0.0038435413,0.00028761],"about_ca_topic_score_codex":0.00010968313,"about_ca_topic_score_gemma":0.00000484801,"teacher_disagreement_score":0.09260449,"about_ca_system_score_codex":0.00006079326,"about_ca_system_score_gemma":0.00030540433,"threshold_uncertainty_score":0.99932176},"labels":[],"label_agreement":null},{"id":"W2949519145","doi":"10.1371/journal.pone.0202458","title":"Melatonin: The smart molecule that differentially modulates autophagy in tumor and normal placental cells","year":2019,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Melatonin; Cell biology; Biology; Endocrinology; Internal medicine; Apoptosis; Chemistry; Biochemistry; Medicine","score_opus":0.015204993929211447,"score_gpt":0.20710332837242348,"score_spread":0.19189833444321203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949519145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962763,0.0012548026,0.0000032287585,0.00029413422,0.00005880253,0.0005680219,0.000009995863,0.00004423462,0.001490436],"genre_scores_gemma":[0.99759537,0.0001166522,0.00008507449,0.0006806495,0.000051891897,0.000021932172,0.00001617591,0.000025884548,0.0014063797],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990423,0.000039953542,0.00015182619,0.00022238758,0.00029413315,0.0002494362],"domain_scores_gemma":[0.9995074,0.00004949504,0.000049094135,0.00027451557,0.00001851455,0.00010097472],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007550333,0.00014912931,0.00028009844,0.000055634355,0.000042925156,0.000023405471,0.00009579343,0.00005413958,0.0007105666],"category_scores_gemma":[0.0000067306587,0.00010379239,0.000053899214,0.00007412789,0.000059696533,0.00007375148,0.000063028274,0.00019595909,0.00014368563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00090449787,0.0033993018,0.22086696,0.00030584054,0.0008155146,0.00021986582,0.0010963761,0.000010815343,0.7713212,0.00044313335,0.0000976411,0.00051888626],"study_design_scores_gemma":[0.002400841,0.0001995736,0.26797435,0.00016401355,0.00014802683,0.000010828561,0.00007560639,0.0037329628,0.72504646,0.000093985596,0.000025094512,0.0001282795],"about_ca_topic_score_codex":0.000031167092,"about_ca_topic_score_gemma":0.000006865657,"teacher_disagreement_score":0.047107372,"about_ca_system_score_codex":0.000028373614,"about_ca_system_score_gemma":0.00003903997,"threshold_uncertainty_score":0.77802056},"labels":[],"label_agreement":null},{"id":"W2950001762","doi":"10.1016/j.jmb.2019.04.048","title":"Exocyst Subcomplex Functions in Autophagosome Biogenesis by Regulating Atg9 Trafficking","year":2019,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"The Wellcome Trust DBT India Alliance; Tokyo Institute of Technology; Georg-August-Universität Göttingen; Jawaharlal Nehru Centre for Advanced Scientific Research; University of Alberta; Wellcome Trust","keywords":"Exocyst; Autophagy; Cell biology; Autophagosome; Biogenesis; Biology; Vesicle; Exocytosis; Vacuole; Golgi apparatus; Vesicular Transport Proteins; Chemistry; Endosome; Intracellular; Membrane; Biochemistry; Vacuolar protein sorting; Cytoplasm; Endoplasmic reticulum; Apoptosis","score_opus":0.010913849344283362,"score_gpt":0.28553577173957384,"score_spread":0.2746219223952905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950001762","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935154,0.0040480345,0.0011823842,0.0004845579,0.00028471567,0.00013840586,0.000007925096,0.0000141502005,0.00032442613],"genre_scores_gemma":[0.99840605,0.000050108636,0.00065891683,0.00058466103,0.00011001362,0.0000021503076,0.00001815513,0.000019725117,0.00015020599],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989135,0.00011291614,0.0004647615,0.00015548755,0.0001286777,0.00022460792],"domain_scores_gemma":[0.9993155,0.00005779733,0.00025554578,0.00018202474,0.0000839413,0.00010517443],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024914337,0.00012588248,0.00039921326,0.00024508208,0.000027504266,0.000007006738,0.00010633305,0.00013488997,0.00027130393],"category_scores_gemma":[0.000053923766,0.00010280883,0.0002153316,0.00021457562,0.00004728522,0.000042865515,0.000019785819,0.00019927172,0.00002861972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024223742,0.00015017293,0.024829926,0.000019507735,0.00015588259,0.0001587721,0.00006043103,0.000093424525,0.96972,0.0002351516,0.0002268389,0.004107669],"study_design_scores_gemma":[0.020606298,0.005298195,0.26667416,0.0006372446,0.0005188056,0.003472208,0.0007681717,0.0014876879,0.6760252,0.0032052654,0.020429801,0.0008769472],"about_ca_topic_score_codex":0.000010477528,"about_ca_topic_score_gemma":0.000001143291,"teacher_disagreement_score":0.29369476,"about_ca_system_score_codex":0.00006815713,"about_ca_system_score_gemma":0.000104394654,"threshold_uncertainty_score":0.41924223},"labels":[],"label_agreement":null},{"id":"W2950938257","doi":"10.1128/jvi.01757-18","title":"HIV-1 Antisense Protein of Different Clades Induces Autophagy and Associates with the Autophagy Factor p62","year":2018,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Government of Canada","keywords":"Autophagy; Biology; Immune system; Cell biology; Antigen presentation; Viral replication; Pathogenesis; Mechanism (biology); Human immunodeficiency virus (HIV); Virology; Virus; Immunology; Genetics; T cell; Apoptosis","score_opus":0.01111791244699532,"score_gpt":0.2667455196417986,"score_spread":0.25562760719480326,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950938257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953576,0.0013058982,0.00006359446,0.0028120147,0.00012109224,0.0002122053,0.000009832293,0.000011181293,0.000106632535],"genre_scores_gemma":[0.99850017,0.00012654322,0.00013381419,0.000573474,0.00040280243,0.0000037297873,0.0000010630923,0.000017682516,0.00024070073],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99887174,0.00015493223,0.0003693901,0.00012682381,0.0002598064,0.00021732172],"domain_scores_gemma":[0.9987985,0.00013990079,0.0005793098,0.00016860418,0.0001920407,0.000121631696],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017903736,0.00016124448,0.000531488,0.000117540025,0.00007954306,0.000012284386,0.0001265925,0.00013974281,0.000193827],"category_scores_gemma":[0.00007152107,0.00007991459,0.000101379,0.00008574153,0.0005090518,0.000074039606,0.000032925924,0.00031113677,0.0000047881804],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023939626,0.00056244526,0.016337203,0.00006131838,0.0010654018,0.00028175238,0.0017263648,7.5680214e-7,0.9722598,0.000512087,0.0006807922,0.0041180686],"study_design_scores_gemma":[0.0026286684,0.0047842846,0.5970131,0.00009184507,0.00020771976,0.00040756064,0.00014894934,0.000031977223,0.39340234,0.00061564794,0.00058105396,0.00008682684],"about_ca_topic_score_codex":0.0000055140295,"about_ca_topic_score_gemma":0.000004228687,"teacher_disagreement_score":0.58067596,"about_ca_system_score_codex":0.000026952903,"about_ca_system_score_gemma":0.00011071136,"threshold_uncertainty_score":0.32588223},"labels":[],"label_agreement":null},{"id":"W2951777278","doi":"10.3389/fphar.2019.00779","title":"RETRACTED: Exploration of Multiple Signaling Pathways Through Which Sodium Tanshinone IIA Sulfonate Attenuates Pathologic Remodeling Experimental Infarction","year":2019,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":16,"is_retracted":true,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"National Science Foundation","keywords":"Autophagy; Medicine; Myocardial infarction; Ligation; Ventricular remodeling; Apoptosis; Pharmacology; Adenosine; Cardiac function curve; Internal medicine; Kinase; Cardiology; Endocrinology; Heart failure; Chemistry; Biochemistry","score_opus":0.03638449786288803,"score_gpt":0.3034114297796123,"score_spread":0.2670269319167242,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951777278","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987804,0.0023065014,0.0058488767,0.00026884399,0.0025542183,0.00075618614,0.000015596404,0.00007973566,0.0003660609],"genre_scores_gemma":[0.9917761,0.0003869132,0.006643575,0.0006788805,0.00021307314,0.000070138776,0.00013497846,0.000033013403,0.00006333163],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99834955,0.00017399016,0.0005120592,0.00039339034,0.00023614959,0.00033487222],"domain_scores_gemma":[0.9992997,0.00006158555,0.00023209838,0.00019118318,0.0001475912,0.00006785045],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032996392,0.00020761343,0.0004782004,0.00019778669,0.000059523474,0.000007534775,0.00012298857,0.00026975997,0.0002773444],"category_scores_gemma":[0.00003863613,0.00020252494,0.00009230932,0.00034124946,0.00007578316,0.0005042734,0.000043266566,0.00043343272,0.000020222473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017719609,0.00048151673,0.035578363,0.000071674986,0.00009813299,0.000051589086,0.0026285513,0.0020155618,0.9555342,0.000029849092,0.00085184694,0.0008867092],"study_design_scores_gemma":[0.007284316,0.00061427586,0.0040840376,0.00006984498,0.0001169761,0.000022792237,0.0030210437,0.041104972,0.9412461,0.0016826352,0.00049153896,0.00026150138],"about_ca_topic_score_codex":0.000031341086,"about_ca_topic_score_gemma":0.0000013278645,"teacher_disagreement_score":0.03908941,"about_ca_system_score_codex":0.00016950075,"about_ca_system_score_gemma":0.00009956792,"threshold_uncertainty_score":0.8258727},"labels":[],"label_agreement":null},{"id":"W2953106546","doi":"10.1080/15548627.2019.1628545","title":"Autophagy metabolically suppresses CD8<sup>+</sup> T cell antitumor immunity","year":2019,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Spinal Cord Injury BC; University of Victoria","funders":"BC Cancer Foundation; Canadian Cancer Society","keywords":"Autophagy; ATG5; Biology; Immune system; Cell biology; CD8; T cell; Immunity; Cytotoxic T cell; Cancer research; Immunology; Apoptosis; Biochemistry","score_opus":0.008985984937015806,"score_gpt":0.2572148577439833,"score_spread":0.24822887280696748,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953106546","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9633051,0.0049943826,0.000092446324,0.00043041966,0.0005138609,0.000936407,0.000064855405,0.0005326123,0.029129874],"genre_scores_gemma":[0.972087,0.00034357543,0.0009025906,0.003276836,0.00040067,0.000061851366,0.00015071988,0.000115211864,0.022661539],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968585,0.00018784465,0.00065520377,0.0007459977,0.00067568093,0.00087680237],"domain_scores_gemma":[0.9972785,0.00020626458,0.00019394695,0.0016158109,0.0002177407,0.00048770208],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00033564432,0.0005417121,0.0010040427,0.0002543446,0.00018787505,0.00008175147,0.00054884685,0.0002885333,0.01047777],"category_scores_gemma":[0.00009308198,0.00047118572,0.00048416507,0.00049228343,0.00017994673,0.0003402256,0.0002028041,0.00062586827,0.004360003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037845192,0.009900918,0.026877005,0.0025497584,0.0027390432,0.0033342903,0.0048890356,0.0015156801,0.85571444,0.023543304,0.038301002,0.026850995],"study_design_scores_gemma":[0.008525552,0.0009508552,0.13506202,0.00014443092,0.00057495903,0.0002384855,0.00029587833,0.004246365,0.69330317,0.0012278329,0.15446807,0.0009623941],"about_ca_topic_score_codex":0.00016494376,"about_ca_topic_score_gemma":0.0000014956142,"teacher_disagreement_score":0.1624113,"about_ca_system_score_codex":0.000080674465,"about_ca_system_score_gemma":0.0004397467,"threshold_uncertainty_score":0.999774},"labels":[],"label_agreement":null},{"id":"W2954965931","doi":"10.1080/15548627.2019.1639300","title":"Subnanometer resolution cryo-EM structure of <i>Arabidopsis thaliana</i> ATG9","year":2019,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"National Natural Science Foundation of China","keywords":"Autophagy; Cell biology; Biology; Autophagosome; Transmembrane protein; Vacuole; Arabidopsis; Membrane protein; Cytoplasm; Membrane; Biochemistry; Receptor; Mutant; Gene","score_opus":0.0074376011416428045,"score_gpt":0.24372995697074995,"score_spread":0.23629235582910715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2954965931","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936674,0.0016069723,0.000044311462,0.00014900409,0.0004123093,0.00037756245,0.000056863253,0.00007922361,0.0036063073],"genre_scores_gemma":[0.9938173,0.00005677215,0.0004454929,0.00096410274,0.00015307528,0.0000049628857,0.00006514373,0.000034611057,0.004458512],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99871683,0.000043941498,0.0003127174,0.00030944392,0.0003293028,0.00028773447],"domain_scores_gemma":[0.99898046,0.000041410647,0.00013757072,0.00062009407,0.00009225458,0.00012820773],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007702499,0.0001869702,0.00040683165,0.00012676271,0.000035366185,0.000010454859,0.0001406391,0.00016277365,0.0035491968],"category_scores_gemma":[0.000023498866,0.00015464552,0.00020151895,0.00027043547,0.00005915212,0.00011277234,0.000038389244,0.00015844677,0.00024944762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012035345,0.0005450359,0.041770536,0.00061654474,0.0007536373,0.00014055523,0.0014114497,0.00007470336,0.9230421,0.0060429196,0.008239538,0.016159415],"study_design_scores_gemma":[0.00392096,0.0007303832,0.42674327,0.00016351696,0.00025071634,0.00008046379,0.00017377497,0.00045189937,0.5483417,0.0022389623,0.016544934,0.00035945643],"about_ca_topic_score_codex":0.00003746106,"about_ca_topic_score_gemma":0.0000043975188,"teacher_disagreement_score":0.38497272,"about_ca_system_score_codex":0.000051268984,"about_ca_system_score_gemma":0.000094394716,"threshold_uncertainty_score":0.9973617},"labels":[],"label_agreement":null},{"id":"W2955017401","doi":"10.1158/1538-7445.am2019-2619","title":"Abstract 2619: DNA damage agents promote TFEB function and induce pro-survival autophagy signals","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"TFEB; Autophagy; DNA damage; Cancer research; Biology; Cell biology; mTORC1; DNA; PI3K/AKT/mTOR pathway; Biochemistry; Signal transduction","score_opus":0.10367447670212596,"score_gpt":0.42256633888226797,"score_spread":0.318891862180142,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2955017401","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890193,0.0013600657,0.0000054271304,0.0005593844,0.00031533604,0.0013113534,0.000019542784,0.000066680004,0.007342935],"genre_scores_gemma":[0.99247485,0.00029400544,0.000011900902,0.0002572725,0.00040124208,0.00015662382,0.000024489393,0.000043547905,0.006336046],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99784356,0.0001118821,0.00021234852,0.00046407568,0.0008467517,0.0005213519],"domain_scores_gemma":[0.9988784,0.000077370205,0.000053988282,0.00043097496,0.00024201843,0.00031720815],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00085549185,0.00015856855,0.0002728256,0.00018376156,0.00013785392,0.0000613677,0.00014380304,0.00014441504,0.0048387214],"category_scores_gemma":[0.000060961498,0.00013293815,0.00006213154,0.0003383112,0.00013028989,0.00014836216,0.0000869708,0.0005826908,0.0004567409],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013954659,0.0003067649,0.011855132,0.00062688196,0.00027594855,0.00013198983,0.00057735987,0.0000070753,0.953309,0.00032418032,0.0025987718,0.028591458],"study_design_scores_gemma":[0.003918468,0.0008751329,0.8002854,0.0004239173,0.00005264082,0.000006915821,0.0002723611,0.00018756662,0.18013991,0.0014137409,0.012166424,0.00025749294],"about_ca_topic_score_codex":0.00015512377,"about_ca_topic_score_gemma":0.0000075648195,"teacher_disagreement_score":0.7884303,"about_ca_system_score_codex":0.00015520207,"about_ca_system_score_gemma":0.00047902783,"threshold_uncertainty_score":0.996071},"labels":[],"label_agreement":null},{"id":"W2955538712","doi":"10.4049/jimmunol.1900117","title":"Tim-4 Inhibits NLRP3 Inflammasome via the LKB1/AMPKα Pathway in Macrophages","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Peking University; Chinese Academy of Medical Sciences; Chinese Academy of Sciences; Academy of Medical Sciences; York University","keywords":"Inflammasome; AMPK; Inflammation; Autophagy; Steatosis; Cell biology; Chemistry; Nonalcoholic fatty liver disease; Gene knockdown; Downregulation and upregulation; Fatty liver; Cancer research; Immunology; Phosphorylation; Biology; Protein kinase A; Apoptosis; Medicine; Endocrinology; Internal medicine; Biochemistry","score_opus":0.006793905239658298,"score_gpt":0.23947780622347936,"score_spread":0.23268390098382105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2955538712","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98079014,0.013818366,0.000020702775,0.0036108098,0.00045801327,0.00023520942,0.0000013089981,0.000008517465,0.0010569073],"genre_scores_gemma":[0.9963651,0.0013467622,0.000020961557,0.0011494774,0.0001910535,0.0000023166544,0.0000015851289,0.00001826888,0.00090452784],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987128,0.00027649032,0.0004706378,0.00007899683,0.00020032283,0.00026076369],"domain_scores_gemma":[0.9988596,0.00026266943,0.0003265819,0.00040410037,0.000105451094,0.00004159943],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00078073476,0.00013781279,0.00036075915,0.00013458611,0.000057804446,0.000008523564,0.0003558382,0.00010957377,0.0009642418],"category_scores_gemma":[0.0000625183,0.000065869994,0.0001301803,0.00019486941,0.00017662927,0.00009247879,0.00007141041,0.00069566,0.00024660054],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036818904,0.00033960436,0.0076657855,0.00003427837,0.0007533291,0.00039116212,0.0039068772,0.0000930819,0.958036,0.00075536704,0.00061786344,0.023724778],"study_design_scores_gemma":[0.013374029,0.0038767534,0.48643106,0.00046171492,0.00025350152,0.006550818,0.0022465826,0.000126161,0.45175532,0.007746312,0.026813082,0.0003646446],"about_ca_topic_score_codex":0.000019616706,"about_ca_topic_score_gemma":0.0000043555483,"teacher_disagreement_score":0.50628066,"about_ca_system_score_codex":0.000058475813,"about_ca_system_score_gemma":0.00015073585,"threshold_uncertainty_score":0.99994904},"labels":[],"label_agreement":null},{"id":"W2955656412","doi":"10.12688/f1000research.17196.1","title":"mTOR as a central regulator of lifespan and aging","year":2019,"lang":"en","type":"preprint","venue":"F1000Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":437,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Occupational Cancer Research Centre; Université de Montréal; Hôpital Maisonneuve-Rosemont; McGill University; Jewish General Hospital","funders":"Lady Davis Institute for Medical Research; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Terry Fox Research Institute; Azrieli Foundation; Israel Science Foundation; International Development Research Centre","keywords":"Proteostasis; Autophagy; PI3K/AKT/mTOR pathway; Regulator; Cell biology; Biology; Mechanistic target of rapamycin; Nutrient sensing; mTORC2; Senescence; Neuroscience; Cellular senescence; Longevity; Cell metabolism; Cell; mTORC1; Signal transduction; Phenotype; Apoptosis; Genetics","score_opus":0.031597320651984354,"score_gpt":0.3683454684601126,"score_spread":0.3367481478081283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2955656412","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9860143,0.0070223855,0.000026004329,0.0013670702,0.00025840127,0.001076811,0.000060724626,0.000058126232,0.0041161515],"genre_scores_gemma":[0.98652506,0.0015096569,0.00021607096,0.00020313423,0.0004675851,0.000035468423,0.000076800134,0.000058159898,0.010908048],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99798995,0.00010077631,0.00028116134,0.00044811284,0.0007083544,0.00047161712],"domain_scores_gemma":[0.99842787,0.00010554108,0.0000934304,0.00080035895,0.00018263458,0.00039016598],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00036442664,0.00020128343,0.00051071483,0.00019208694,0.000040296072,0.000033169737,0.00023826706,0.00026016266,0.000941462],"category_scores_gemma":[0.00015644584,0.0001763927,0.00015949243,0.0001145574,0.0002017992,0.00003403098,0.00062559743,0.0007412338,0.00009484758],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009337301,0.0028879878,0.6625859,0.029521702,0.005926617,0.0020034153,0.010436512,0.00023320975,0.10363028,0.012602107,0.058924083,0.10191086],"study_design_scores_gemma":[0.00541765,0.0010291514,0.86956453,0.0035640737,0.00036232648,0.00010018337,0.00049786514,0.0031139904,0.07825754,0.007345924,0.030041816,0.00070496026],"about_ca_topic_score_codex":0.00021748981,"about_ca_topic_score_gemma":0.0000016155143,"teacher_disagreement_score":0.20697859,"about_ca_system_score_codex":0.00008054445,"about_ca_system_score_gemma":0.0009557609,"threshold_uncertainty_score":0.9999718},"labels":[],"label_agreement":null},{"id":"W2964384918","doi":"10.1007/s10549-019-05381-y","title":"A randomized, double-blind, window of opportunity trial evaluating the effects of chloroquine in breast cancer patients","year":2019,"lang":"en","type":"article","venue":"Breast Cancer Research and Treatment","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Regional Cancer Foundation; University of Ottawa; McMaster University; Health Sciences North; Ottawa Hospital","funders":"Canadian Cancer Society","keywords":"Chloroquine; Placebo; Medicine; Breast cancer; Adverse effect; Randomized controlled trial; Internal medicine; Oncology; Toxicity; Clinical trial; Cancer; Pharmacology; Surgery; Pathology; Malaria","score_opus":0.0904509321332827,"score_gpt":0.43191195704074076,"score_spread":0.34146102490745806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2964384918","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989574,0.0025072505,1.9138555e-7,0.0009388852,0.000141093,0.006446743,0.00017006687,0.0000071538448,0.00021458477],"genre_scores_gemma":[0.9944117,0.0030043432,0.0000032018413,0.00004208457,0.00014199865,0.0019381179,0.000030661457,0.000019682595,0.00040818437],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99778724,0.0003574503,0.00040719294,0.00029549442,0.00078229595,0.00037033763],"domain_scores_gemma":[0.9983309,0.0005449486,0.00016873702,0.0003403826,0.0003880107,0.00022705873],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00088427885,0.00018833461,0.00076077314,0.00018549284,0.000066488596,0.00001232296,0.000103657905,0.00006953024,0.00048093344],"category_scores_gemma":[0.000044151508,0.00010280313,0.00015780845,0.00032284853,0.0002986304,0.00006994848,0.000057279507,0.00017765534,0.0000034954571],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.89929396,0.0022674564,0.05528811,0.000282484,0.0006993585,0.000012333512,0.00044477315,0.000003582481,0.00071169063,0.00006327712,0.000016546932,0.04091641],"study_design_scores_gemma":[0.87331516,0.0036350254,0.118649654,0.0006158945,0.00020384078,0.000008867927,0.00006541246,0.000070676084,0.0032517163,0.000096659955,0.000008744615,0.00007837482],"about_ca_topic_score_codex":0.010977313,"about_ca_topic_score_gemma":0.00017958954,"teacher_disagreement_score":0.06336154,"about_ca_system_score_codex":0.0002748775,"about_ca_system_score_gemma":0.0009445342,"threshold_uncertainty_score":0.9956087},"labels":[],"label_agreement":null},{"id":"W2964892149","doi":"10.1074/jbc.ra119.008923","title":"Inhibition of the ULK1 protein complex suppresses Staphylococcus-induced autophagy and cell death","year":2019,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Ministry of Higher Education and Scientific Research; Engineering and Physical Sciences Research Council; Tenovus; Natural Sciences and Engineering Research Council of Canada; Cancer Research UK; Government of Canada","keywords":"Autophagy; Biology; Autophagy-related protein 13; Cell biology; Microbiology; Intracellular parasite; Lysosome; Intracellular; Programmed cell death; Staphylococcus aureus; Protein kinase A; Cytosol; Salmonella; Kinase; Bacteria; Protein phosphorylation; Biochemistry; Apoptosis; Enzyme; Genetics","score_opus":0.029399102905880495,"score_gpt":0.2676921134613693,"score_spread":0.2382930105554888,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2964892149","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977978,0.00042930612,0.000005084524,0.00018325023,0.000027713428,0.00017980792,0.0000102053855,0.0000065755644,0.0013602843],"genre_scores_gemma":[0.9993815,0.00004588302,0.00014185921,0.00015884197,0.00011791657,0.000002056251,0.000003950991,0.0000052016167,0.0001427788],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928284,0.000032769774,0.00030302352,0.00010230816,0.00016675996,0.00011232516],"domain_scores_gemma":[0.99930394,0.000044077482,0.00030994974,0.0001454634,0.000106312546,0.00009026758],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012344381,0.00010053346,0.00028293332,0.0000129271075,0.000025044374,0.000006483954,0.000089172216,0.00013147567,0.00053425995],"category_scores_gemma":[0.000053201496,0.000051495506,0.00014247045,0.00005671323,0.00007188315,0.000029171317,0.000041666415,0.00023390709,0.0000019798433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024736975,0.00019410245,0.008843637,0.00014830189,0.00003187342,0.00001622637,0.000023818828,6.374135e-7,0.9902721,0.000013273768,0.000061878694,0.0001467921],"study_design_scores_gemma":[0.0012329667,0.00032738107,0.08878175,0.00012322752,0.000024606508,0.000049743074,0.0000668228,0.000009067449,0.9086897,0.00041502577,0.00022587828,0.000053855812],"about_ca_topic_score_codex":0.0000014015345,"about_ca_topic_score_gemma":2.1207507e-8,"teacher_disagreement_score":0.08158241,"about_ca_system_score_codex":0.000020044094,"about_ca_system_score_gemma":0.00006860847,"threshold_uncertainty_score":0.5849772},"labels":[],"label_agreement":null},{"id":"W2965452705","doi":"10.1016/j.biopsych.2019.07.018","title":"Neuronal Autophagy in Synaptic Functions and Psychiatric Disorders","year":2019,"lang":"en","type":"review","venue":"Biological Psychiatry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institutes of Health; Stanley Foundation; National Center for Research Resources; National Institute of Mental Health; National Alliance for Research on Schizophrenia and Depression; U.S. Department of Defense","keywords":"Autophagy; Neuroscience; Synaptic plasticity; Biology; Homeostasis; Synapse; Homeostatic plasticity; Synaptic scaling; Organelle; Metaplasticity; Cell biology; Receptor; Biochemistry","score_opus":0.049164892220271636,"score_gpt":0.3396567615266631,"score_spread":0.2904918693063914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2965452705","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.003815073,0.99025065,0.000010481174,0.00030086684,0.0021294449,0.0011944528,0.00005313883,0.000112969836,0.0021329478],"genre_scores_gemma":[0.000990468,0.99690986,0.00016892282,0.0005471657,0.00052116,0.000118405536,0.00019965987,0.000046960304,0.00049740105],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978407,0.0001808531,0.0006353399,0.0007860563,0.00014898874,0.0004080484],"domain_scores_gemma":[0.99898237,0.00014410426,0.00019778813,0.00045744894,0.0000125505985,0.00020573584],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013338256,0.0005028437,0.0015697564,0.00032354443,0.000070097805,0.000017003806,0.00017660164,0.00071398995,0.00040632524],"category_scores_gemma":[0.00003854247,0.00032632245,0.000613367,0.0005081471,0.00014478521,0.00003255664,0.00007036994,0.00078283035,0.00041332247],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016701131,0.0012572408,0.011583235,0.0103672845,0.0005158933,0.00001852585,0.0000069661914,4.7387698e-7,3.7592133e-7,0.0028893768,0.0026486632,0.97054493],"study_design_scores_gemma":[0.0012240021,0.000985194,0.02871147,0.0018227361,0.0009101123,0.000105583604,0.000017569135,0.000008285316,8.9898e-9,0.0015021444,0.96424043,0.00047248285],"about_ca_topic_score_codex":0.0000066469615,"about_ca_topic_score_gemma":0.000005917057,"teacher_disagreement_score":0.97007245,"about_ca_system_score_codex":0.000049305756,"about_ca_system_score_gemma":0.0004028152,"threshold_uncertainty_score":0.9999189},"labels":[],"label_agreement":null},{"id":"W2965938893","doi":"10.1038/s41598-019-47659-7","title":"Colorectal cancer cells respond differentially to autophagy inhibition in vivo","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Université de Sherbrooke; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Autophagy; ATG5; PI3K/AKT/mTOR pathway; Cell biology; Biology; Autophagosome; Lysosome; Protein kinase B; Cell growth; Cell culture; Cancer research; Cancer cell; ULK1; Programmed cell death; Gene knockdown; Cancer; Signal transduction; Apoptosis; Kinase; Biochemistry; Genetics; AMPK","score_opus":0.008137094949828798,"score_gpt":0.2706139905573479,"score_spread":0.26247689560751913,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2965938893","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9897804,0.00012255851,0.0000142395,0.00018585678,0.00655661,0.00088589697,0.00000804674,0.00006435306,0.0023820256],"genre_scores_gemma":[0.9793445,0.0000054994857,0.00006257967,0.00024392242,0.000094542826,0.000064222215,0.000023286291,0.000019852083,0.020141598],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980639,0.000036410533,0.0004043915,0.0006672389,0.0005079931,0.000320053],"domain_scores_gemma":[0.9990366,0.00001829138,0.00012531436,0.00050380785,0.00010434642,0.00021160877],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00048489458,0.00014049652,0.0002621922,0.00033256612,0.00006906749,0.00008237935,0.000044118588,0.00008231594,0.004274164],"category_scores_gemma":[0.000030386858,0.00012235032,0.00009686725,0.0005726261,0.00006794988,0.00010656967,0.000048634236,0.00011292211,0.0002004225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022868672,0.00017179994,0.00710975,0.000033386616,0.00001636817,0.0013220581,0.00046713455,0.00005554699,0.9826947,0.000028520533,0.007318669,0.00055340497],"study_design_scores_gemma":[0.00057683047,0.000113285576,0.051971097,0.00015209387,0.000019639381,0.000080264566,0.000038636263,0.000084216845,0.93517554,0.00067201257,0.010973755,0.00014263506],"about_ca_topic_score_codex":0.00007234463,"about_ca_topic_score_gemma":0.0000775832,"teacher_disagreement_score":0.047519144,"about_ca_system_score_codex":0.0001472045,"about_ca_system_score_gemma":0.00034550967,"threshold_uncertainty_score":0.9966361},"labels":[],"label_agreement":null},{"id":"W2966086076","doi":"10.3892/etm.2019.7845","title":"GSK343 induces autophagy and downregulates the AKT/mTOR signaling pathway in pancreatic cancer cells","year":2019,"lang":"en","type":"article","venue":"Experimental and Therapeutic Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China; Public Health Agency of Canada","keywords":"PI3K/AKT/mTOR pathway; Pancreatic cancer; Cell cycle; Protein kinase B; Autophagy; Viability assay; Cancer research; Apoptosis; Cell growth; Oncogene; Cancer; Biology; Cell; Cancer cell; Signal transduction; Chemistry; Cell biology; Biochemistry","score_opus":0.019330726959646098,"score_gpt":0.29337748367570554,"score_spread":0.27404675671605944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2966086076","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91213936,0.084987246,0.0000020550012,0.0013598489,0.00023882005,0.00057656737,0.000002849268,0.000031156273,0.0006621346],"genre_scores_gemma":[0.9955347,0.00056754396,0.000018937024,0.002812774,0.00023633921,0.00007604417,0.0000058274277,0.000025304915,0.0007225284],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988243,0.00007015755,0.0002760512,0.00031758467,0.00024802997,0.00026388932],"domain_scores_gemma":[0.99937797,0.0001358824,0.00007579959,0.00025184653,0.000018283543,0.00014020904],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020725037,0.00023593816,0.00042814272,0.00007943509,0.000085437096,0.000015171455,0.000097487726,0.00007983647,0.0014957894],"category_scores_gemma":[0.000005233646,0.00012985013,0.000039460538,0.00013723508,0.00027358934,0.00005276606,0.00004953386,0.00017347668,0.000013720905],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026416936,0.00012073739,0.0048816376,0.00005673504,0.00013923555,0.000024840845,0.004840036,0.0000014677345,0.9820937,0.0005216787,0.000022124845,0.007033661],"study_design_scores_gemma":[0.004952926,0.00088146987,0.03497653,0.0005049817,0.00008266882,0.0000468624,0.0056562475,0.0003212929,0.9505477,0.000713118,0.0011001488,0.0002160541],"about_ca_topic_score_codex":0.00025779515,"about_ca_topic_score_gemma":0.0000026996265,"teacher_disagreement_score":0.0844197,"about_ca_system_score_codex":0.00004101214,"about_ca_system_score_gemma":0.000047386406,"threshold_uncertainty_score":0.999417},"labels":[],"label_agreement":null},{"id":"W2966577796","doi":"10.1042/cs20190672","title":"Mitochondrial ROS-induced lysosomal dysfunction impairs autophagic flux and contributes to M1 macrophage polarization in a diabetic condition","year":2019,"lang":"en","type":"article","venue":"Clinical Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":154,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"China Postdoctoral Science Foundation; National Natural Science Foundation of China; Arizona State University","keywords":"Autophagy; Mitochondrion; Macrophage polarization; Lysosome; Cell biology; Macrophage; Medicine; Biology; Apoptosis; Genetics; Biochemistry; Enzyme","score_opus":0.015980126673216688,"score_gpt":0.3380195875338373,"score_spread":0.32203946086062063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2966577796","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99638945,0.0001068843,0.00033928643,0.0007009235,0.0012580832,0.00087338546,0.000007744681,0.000056887726,0.00026735727],"genre_scores_gemma":[0.99760824,0.0000087014005,0.00016058577,0.0016050239,0.00018395662,0.000021809186,0.000021522497,0.000009978854,0.00038016363],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99821234,0.00008841712,0.00046759527,0.000549011,0.00033300705,0.00034963863],"domain_scores_gemma":[0.9989597,0.00022069232,0.000094913376,0.00028103415,0.00010853497,0.0003351343],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007326077,0.0001299841,0.0003296518,0.00018947857,0.00010614414,0.00006517213,0.00013520698,0.0001463365,0.00022147517],"category_scores_gemma":[0.0008994586,0.00010945193,0.00007116184,0.00074675144,0.0002790658,0.00026680916,0.000069091315,0.00022516871,0.00023505445],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005147881,0.00033892525,0.2770936,0.000025316496,0.000017101189,0.000027511116,0.00008684575,0.0000118506,0.71340036,0.00072421186,0.00010099478,0.0076585114],"study_design_scores_gemma":[0.004238259,0.0010033374,0.96930945,0.00009374079,0.000033809203,0.00000646449,0.00003987675,0.0036739295,0.020466251,0.0008410688,0.00016725861,0.00012654487],"about_ca_topic_score_codex":0.00003399882,"about_ca_topic_score_gemma":0.000004892061,"teacher_disagreement_score":0.6929341,"about_ca_system_score_codex":0.00011311379,"about_ca_system_score_gemma":0.0003087424,"threshold_uncertainty_score":0.44633204},"labels":[],"label_agreement":null},{"id":"W2967952828","doi":"10.1038/s41598-019-48047-x","title":"Functional Transcriptome Analysis in ARSACS KO Cell Model Reveals a Role of Sacsin in Autophagy","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Università degli Studi di Verona; Ministero della Salute; E-Rare","keywords":"Autophagy; Neurodegeneration; Cell biology; Transcriptome; Mitophagy; Biology; Autophagosome; Mitochondrion; ATG8; Spinocerebellar ataxia; Biochemistry; Gene expression; Gene; Apoptosis; Disease; Medicine","score_opus":0.010218084517450706,"score_gpt":0.24449307598724138,"score_spread":0.23427499146979067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2967952828","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942056,0.00090248085,0.00015153094,0.000042752312,0.0006128669,0.00038640565,0.0000063143375,0.000022867365,0.0036691793],"genre_scores_gemma":[0.98902386,0.000007863976,0.00023407911,0.00006591619,0.00001537275,0.000017182689,0.000086711385,0.000012788745,0.010536229],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99771565,0.00004028705,0.0007476981,0.0006176861,0.00060385175,0.00027480154],"domain_scores_gemma":[0.9987714,0.0000196375,0.000225954,0.00076434395,0.00010603539,0.000112586255],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010598801,0.00013591089,0.0004954173,0.000962367,0.000028435892,0.000024158133,0.000074040756,0.00009572778,0.0008865715],"category_scores_gemma":[0.00002262797,0.00012351309,0.00026437643,0.0018489284,0.000091697446,0.00013453046,0.000016295602,0.00014105157,0.000027722639],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015079965,0.0007499487,0.2185214,0.00009261135,0.00012675495,0.0003269501,0.0010159103,0.019098848,0.75888723,0.00008953935,0.00050979725,0.0004302005],"study_design_scores_gemma":[0.002710563,0.00012510538,0.62666607,0.00018903882,0.0005815461,0.000074798474,0.0004617752,0.08934083,0.2510975,0.02727427,0.001058609,0.00041991306],"about_ca_topic_score_codex":0.00006199113,"about_ca_topic_score_gemma":0.00003072066,"teacher_disagreement_score":0.50778973,"about_ca_system_score_codex":0.000081863756,"about_ca_system_score_gemma":0.0003077948,"threshold_uncertainty_score":0.9707336},"labels":[],"label_agreement":null},{"id":"W2969305581","doi":"10.1002/prot.25805","title":"Target highlights in CASP13: Experimental target structures through the eyes of their authors","year":2019,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto; University of Windsor","funders":"Eshelman Institute for Innovation, University of North Carolina at Chapel Hill; National Institute of General Medical Sciences; National Institutes of Health; ETH Zürich Foundation; Innovative Medicines Initiative; Canada Foundation for Innovation; Wellcome Trust; AbbVie; European Federation of Pharmaceutical Industries and Associations; Eidgenössische Technische Hochschule Zürich; Genome Canada; Biotechnology and Biological Sciences Research Council; Boehringer Ingelheim; U.S. Department of Energy","keywords":"Computational biology; Computer science; Chemistry; Biology","score_opus":0.008935375033442439,"score_gpt":0.24337251902744392,"score_spread":0.23443714399400148,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969305581","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944092,0.001209163,0.00045109147,0.00036770612,0.00035772292,0.0012079416,0.000064599786,0.000043047723,0.0018894947],"genre_scores_gemma":[0.99356645,0.000061215884,0.0054128547,0.0006048777,0.00008603008,0.000015767338,0.00007458099,0.000013666698,0.000164568],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990121,0.000031303112,0.0003865222,0.00013462726,0.00024107829,0.00019437987],"domain_scores_gemma":[0.99944127,0.000020783056,0.00015699654,0.00027973313,0.00003849919,0.00006273676],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006464287,0.0002099068,0.00030042994,0.00008256604,0.00008441189,0.000024916664,0.00008797971,0.00014661445,0.00125318],"category_scores_gemma":[0.000008286524,0.000109401524,0.00007649985,0.00017830313,0.00011280435,0.00022255744,0.000032588152,0.00020794588,0.0000071916043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.020394303,0.0017771494,0.08101845,0.007714672,0.0033509054,0.00005301483,0.18866201,0.0021453358,0.38516018,0.25172114,0.0070661935,0.05093664],"study_design_scores_gemma":[0.008654007,0.0026859653,0.09900791,0.00031248637,0.00013420262,0.00016509416,0.015495851,0.009785487,0.7556563,0.053434692,0.053849958,0.0008180152],"about_ca_topic_score_codex":0.000029418567,"about_ca_topic_score_gemma":0.0000031136851,"teacher_disagreement_score":0.37049615,"about_ca_system_score_codex":0.000025742787,"about_ca_system_score_gemma":0.000057016343,"threshold_uncertainty_score":0.99965984},"labels":[],"label_agreement":null},{"id":"W2969307721","doi":"10.1016/j.ejphar.2019.172616","title":"Mechanisms of simvastatin myotoxicity: The role of autophagy flux inhibition","year":2019,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; University of Victoria; Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Children's Hospital Research Institute of Manitoba; University of Manitoba; Research Manitoba","keywords":"Simvastatin; Autophagy; C2C12; Cell biology; Myotoxin; Programmed cell death; Farnesyl pyrophosphate; Statin; Apoptosis; Cell culture; Geranylgeranyl pyrophosphate; Chemistry; Viability assay; Biology; Pharmacology; Myocyte; Biochemistry; Myogenesis; Prenylation; Venom","score_opus":0.008886323504841472,"score_gpt":0.2710620427369335,"score_spread":0.26217571923209204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969307721","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932033,0.000685229,0.0006011795,0.00040071772,0.0004113319,0.00020986167,0.000008228862,0.000008138278,0.0044720373],"genre_scores_gemma":[0.9979267,0.00006568665,0.00031083255,0.0012128592,0.00018308291,6.8617356e-7,0.0000027398994,0.000023607066,0.00027382126],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984485,0.0005070252,0.00057451235,0.00008832534,0.00023916879,0.0001425049],"domain_scores_gemma":[0.9988021,0.000107162305,0.00067779736,0.000118582015,0.00021507661,0.000079238314],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008355878,0.000103503015,0.00034040507,0.00012470267,0.000023430066,0.000002814609,0.00015127708,0.00002358515,0.0025445782],"category_scores_gemma":[0.000025379828,0.000068555346,0.00018311766,0.00012148435,0.00009065118,0.0000628058,0.00004078149,0.00025876754,0.00006829595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00070416764,0.00026188273,0.00008969717,0.000040257633,0.00025685245,0.00019090356,0.0004798697,0.000061205064,0.99079704,0.0009404437,0.0011743405,0.0050033275],"study_design_scores_gemma":[0.0034976962,0.0017394761,0.0042433264,0.0000685191,0.000232599,0.00019193416,0.00024381556,0.00021801075,0.98429406,0.0014647988,0.0037506167,0.000055143126],"about_ca_topic_score_codex":9.4676955e-7,"about_ca_topic_score_gemma":4.9564882e-8,"teacher_disagreement_score":0.0065029883,"about_ca_system_score_codex":0.000019631872,"about_ca_system_score_gemma":0.00010325337,"threshold_uncertainty_score":0.99836725},"labels":[],"label_agreement":null},{"id":"W2969695551","doi":"10.1002/1878-0261.12567","title":"Emerging roles of HECT‐type E3 ubiquitin ligases in autophagy regulation","year":2019,"lang":"en","type":"review","venue":"Molecular Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research","funders":"Medical Research Council; Associazione Italiana per la Ricerca sul Cancro","keywords":"Autophagy; Ubiquitin; Cell biology; Biology; Neurodegeneration; Mitophagy; Lysosome; ATG16L1; Biochemistry; Medicine; Gene","score_opus":0.043175383031743474,"score_gpt":0.40648420080499803,"score_spread":0.3633088177732546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969695551","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0057709133,0.9901593,0.000043117918,0.00006992111,0.00028298335,0.0010094921,0.0000100533025,0.0000426578,0.0026115607],"genre_scores_gemma":[0.0045899237,0.99388254,0.00019296455,0.00028206347,0.00012741098,0.000068123154,0.00027906906,0.00008061595,0.0004972758],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99785477,0.00035637425,0.00081332854,0.00043114965,0.00022967158,0.00031469454],"domain_scores_gemma":[0.9986287,0.0001481085,0.0004894255,0.0005477549,0.00009490523,0.00009114508],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000269134,0.00034047477,0.00226591,0.00048472374,0.000018844295,0.000004805129,0.00017954658,0.0006036167,0.00034807526],"category_scores_gemma":[0.00012991644,0.00030301616,0.00047265034,0.0004771202,0.00007795027,0.000029963925,0.00007527612,0.0003661528,0.000104535255],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000103228216,0.00030459234,0.000013407079,0.008530756,0.0003291237,0.0007474062,0.00013338694,0.000012214664,0.0010770494,0.000786756,0.0002022826,0.98775977],"study_design_scores_gemma":[0.0010848976,0.00083649106,0.00012046213,0.006642927,0.0012336156,0.00015058105,0.000021383961,0.000053823405,0.0024868418,0.00024863548,0.9868565,0.00026382072],"about_ca_topic_score_codex":0.000017606302,"about_ca_topic_score_gemma":0.000008493539,"teacher_disagreement_score":0.98749596,"about_ca_system_score_codex":0.00027406623,"about_ca_system_score_gemma":0.0011330629,"threshold_uncertainty_score":0.9999422},"labels":[],"label_agreement":null},{"id":"W2970684247","doi":"10.3389/fcell.2019.00192","title":"Pleiotropic Effects of mTOR and Autophagy During Development and Aging","year":2019,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":120,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Autophagy; PI3K/AKT/mTOR pathway; TFEB; Biology; Neurodegeneration; Longevity; Organism; Mechanistic target of rapamycin; Cell biology; Pleiotropy; Nutrient sensing; Model organism; Genetics; Disease; Phenotype; Signal transduction; Gene; Medicine","score_opus":0.01285685497351122,"score_gpt":0.2674638671638235,"score_spread":0.25460701219031223,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2970684247","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.18482044,0.8139903,0.000021855001,0.0000029498492,0.00036106657,0.0005843041,0.000004983418,0.000013482891,0.00020060234],"genre_scores_gemma":[0.0039620087,0.9875493,0.007601683,0.000045091612,0.000034214667,0.000050453604,0.00006929687,0.000028254099,0.0006597091],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99862075,0.00006814243,0.00048125483,0.00047105877,0.00006990886,0.00028887545],"domain_scores_gemma":[0.99951327,0.00008627913,0.00016185502,0.00010430461,0.000010627067,0.00012363686],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008504967,0.00035116152,0.0015088075,0.00032846848,0.000055251898,0.000007761624,0.00006755577,0.0003101981,0.000010624478],"category_scores_gemma":[0.0000140979255,0.0002763905,0.00006105073,0.00010983909,0.00015850415,0.00003053151,0.00015959088,0.00021807612,0.000004421322],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004979899,0.000074536845,0.01353229,0.051782373,0.00033938617,0.000098776276,0.00062160275,1.0036318e-8,0.00019610662,0.000015798794,0.00009673427,0.9331926],"study_design_scores_gemma":[0.0068373713,0.00034039628,0.03941886,0.018367006,0.00078896765,0.00038443672,0.00034990103,0.0000056381828,0.0101452125,0.00011784728,0.9220186,0.0012257925],"about_ca_topic_score_codex":0.000005490744,"about_ca_topic_score_gemma":7.00413e-7,"teacher_disagreement_score":0.9319668,"about_ca_system_score_codex":0.00011478899,"about_ca_system_score_gemma":0.0002844448,"threshold_uncertainty_score":0.9999688},"labels":[],"label_agreement":null},{"id":"W2970727600","doi":"10.3389/fpls.2019.01198","title":"The Function of Autophagy in Lace Plant Programmed Cell Death","year":2019,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Prince Edward Island; Dalhousie University","funders":"Killam Trusts; Dalhousie University; Natural Sciences and Engineering Research Council of Canada; University College Dublin","keywords":"Autophagy; Programmed cell death; Autophagosome; Cell biology; Wortmannin; Vacuole; Acridine orange; Biology; Plant cell; Cell; Organelle; Apoptosis; Cytoplasm; PI3K/AKT/mTOR pathway; Biochemistry; Signal transduction","score_opus":0.007785011022207274,"score_gpt":0.2306854521785913,"score_spread":0.22290044115638402,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2970727600","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99474114,0.001064756,0.00025996345,0.00008037366,0.0010425844,0.00050212117,0.00001529374,0.000019507752,0.0022742823],"genre_scores_gemma":[0.99820507,0.00017508349,0.0007842137,0.00011449994,0.000019850106,0.00001763094,0.0000114768145,0.000005517345,0.0006666884],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9988033,0.000028056389,0.00021388214,0.00024486036,0.00038002201,0.00032985132],"domain_scores_gemma":[0.99950093,0.000045934386,0.00008054363,0.00027067485,0.000025420679,0.000076513],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006476147,0.00008939842,0.00018693788,0.0001905872,0.00005768689,0.000016611732,0.00023926691,0.000045801546,0.000012925791],"category_scores_gemma":[0.00003195454,0.000058656085,0.000033385953,0.00051956077,0.00020031257,0.00011123604,0.000030470565,0.00014605175,0.000011325259],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018462336,0.0004689855,0.9558475,0.000114990704,0.00002142311,0.00010260622,0.0009611361,0.00012965094,0.020441266,0.0017444689,0.0035154787,0.014806274],"study_design_scores_gemma":[0.003547756,0.0006699606,0.9043182,0.0002396917,0.000028168173,0.00002526514,0.0012947919,0.023796534,0.052553415,0.0014376192,0.011863551,0.00022500711],"about_ca_topic_score_codex":0.000043978365,"about_ca_topic_score_gemma":0.000010856259,"teacher_disagreement_score":0.051529247,"about_ca_system_score_codex":0.00009451834,"about_ca_system_score_gemma":0.0002749288,"threshold_uncertainty_score":0.23919258},"labels":[],"label_agreement":null},{"id":"W2971778440","doi":"10.1104/pp.19.00647","title":"Chemical Screening Pipeline for Identification of Specific Plant Autophagy Modulators","year":2019,"lang":"en","type":"article","venue":"PLANT PHYSIOLOGY","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Knut och Alice Wallenbergs Stiftelse; Stiftelsen för Strategisk Forskning","keywords":"Autophagy; Arabidopsis; Arabidopsis thaliana; Biology; Cell biology; Computational biology; Programmed cell death; Biochemistry; Gene; Mutant","score_opus":0.01889501022334751,"score_gpt":0.26477727436818466,"score_spread":0.24588226414483716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2971778440","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966205,0.00029397107,0.0018360788,0.000066730056,0.0002525453,0.00044495193,0.00034441266,0.000043895783,0.00009693994],"genre_scores_gemma":[0.9974413,0.000062335246,0.00036696988,0.00014141665,0.00024973875,0.00002368434,0.0014811599,0.000016984055,0.00021641295],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990857,0.000017861652,0.00033179967,0.0002660797,0.00010496308,0.00019356848],"domain_scores_gemma":[0.9993392,0.0001100812,0.00015164832,0.00028603256,0.000050393788,0.00006260924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009268039,0.00011579186,0.00035471408,0.00006881599,0.00002019951,0.0000026833432,0.000094520576,0.00010161842,0.00015396989],"category_scores_gemma":[0.000017903527,0.00009744878,0.00011762661,0.00006360715,0.000047695816,0.000034449688,0.00002694898,0.000083035695,0.000051496223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001163683,0.00013866072,0.0002467786,0.00010599461,0.000068106165,0.0000027363758,0.000055239118,0.000057838934,0.9936466,0.0017835962,0.0012651808,0.0014655658],"study_design_scores_gemma":[0.0025318763,0.00015490802,0.03285691,0.0000687312,0.000060659902,0.000032384247,0.00004457517,0.029663837,0.92939484,0.0015239648,0.003510566,0.00015674478],"about_ca_topic_score_codex":0.000004186665,"about_ca_topic_score_gemma":9.887635e-8,"teacher_disagreement_score":0.06425178,"about_ca_system_score_codex":0.000014631005,"about_ca_system_score_gemma":0.00002762914,"threshold_uncertainty_score":0.39738458},"labels":[],"label_agreement":null},{"id":"W2972395829","doi":"10.1074/jbc.ra119.009110","title":"Deficiency of the autophagy gene ATG16L1 induces insulin resistance through KLHL9/KLHL13/CUL3-mediated IRS1 degradation","year":2019,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Guelph; SickKids Foundation; University of Toronto; University Health Network; Princess Margaret Cancer Centre","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada; Canadian Institutes of Health Research; Hospital for Sick Children; Ontario Innovation Trust","keywords":"Autophagy; Insulin resistance; IRS1; Degradation (telecommunications); ATG16L1; Cell biology; Gene; Chemistry; Biology; Insulin; Endocrinology; Insulin receptor; Biochemistry","score_opus":0.024804855958329312,"score_gpt":0.2700310094781199,"score_spread":0.2452261535197906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972395829","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916857,0.0057162554,0.00002484695,0.0004949437,0.00015839536,0.00013032342,0.000020561678,0.000014187894,0.001754813],"genre_scores_gemma":[0.9978034,0.00076549075,0.00037063792,0.0003590686,0.00021186747,0.0000021609465,0.000020627444,0.0000061054616,0.00046062414],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99865615,0.00005359076,0.000585198,0.00016916788,0.0003520553,0.00018383817],"domain_scores_gemma":[0.9986462,0.00015276289,0.0006556888,0.00023844559,0.00021660309,0.00009027295],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002500844,0.00014995867,0.0003926085,0.000014250269,0.000045645873,0.000008224356,0.00029338177,0.0002474877,0.0005291588],"category_scores_gemma":[0.00034148054,0.00007304103,0.0002532877,0.00025532304,0.00013536467,0.00007082407,0.0000464734,0.0003766362,0.000009956802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043759847,0.000298779,0.0075652413,0.00008053553,0.000062010724,0.00002452569,0.00005707139,0.0000048729516,0.9907621,0.000031708154,0.00022295481,0.0004525915],"study_design_scores_gemma":[0.0012737971,0.00019624992,0.09703599,0.00016050148,0.000049228824,0.000079965,0.00011394234,0.000008924314,0.89882135,0.0006099648,0.0015500595,0.00010000749],"about_ca_topic_score_codex":0.0000023416349,"about_ca_topic_score_gemma":2.0562787e-7,"teacher_disagreement_score":0.09194074,"about_ca_system_score_codex":0.00006778157,"about_ca_system_score_gemma":0.00017546007,"threshold_uncertainty_score":0.5793918},"labels":[],"label_agreement":null},{"id":"W2975216494","doi":"10.1093/carcin/bgz161","title":"Targeting lysosome function causes selective cytotoxicity in VHL-inactivated renal cell carcinomas","year":2019,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Atlantic Cancer Research Institute; Université de Moncton","funders":"Canadian Institutes of Health Research; New Brunswick Innovation Foundation","keywords":"Lysosome; Biology; Cytotoxic T cell; Cancer research; Autophagy; Cytotoxicity; Cell biology; In vitro; Genetics; Biochemistry","score_opus":0.010918182777606221,"score_gpt":0.23335815150108785,"score_spread":0.22243996872348162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2975216494","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950137,0.001612635,0.00006331669,0.000054362707,0.00020463308,0.00071279035,0.000014041532,0.00011946,0.002205074],"genre_scores_gemma":[0.9982472,0.00006877736,0.000054696542,0.00042241093,0.0002233419,0.00005609139,0.000070404254,0.00005459685,0.000802479],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99828476,0.00011712573,0.00032555615,0.0005166454,0.00030366058,0.00045227254],"domain_scores_gemma":[0.99910736,0.00008156803,0.00011861652,0.0003561244,0.00015861291,0.00017773501],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017279571,0.00026888755,0.0004586363,0.00026944268,0.00008233123,0.000014768219,0.00009644254,0.00018205236,0.00054075517],"category_scores_gemma":[0.000039122067,0.0002482848,0.00015839793,0.0006161061,0.00004012134,0.00014686499,0.000039029263,0.00024115357,0.00018544309],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006192981,0.00015395084,0.40647689,0.00007253804,0.000059445996,0.00006178777,0.00020604307,0.00010139102,0.59191686,0.00001774253,0.00020146623,0.000112583904],"study_design_scores_gemma":[0.0014653945,0.00025324925,0.50390875,0.000035259494,0.00008231989,0.000008535139,0.00019615373,0.0002058783,0.49352008,0.00004025207,0.000116907344,0.00016721668],"about_ca_topic_score_codex":0.0003260911,"about_ca_topic_score_gemma":0.000010562572,"teacher_disagreement_score":0.09839679,"about_ca_system_score_codex":0.00034897326,"about_ca_system_score_gemma":0.00022930962,"threshold_uncertainty_score":0.99999696},"labels":[],"label_agreement":null},{"id":"W2976218487","doi":"10.1007/s00383-019-04566-2","title":"The role of autophagy in intestinal epithelial injury","year":2019,"lang":"en","type":"article","venue":"Pediatric Surgery International","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"","keywords":"Autophagy; Wortmannin; Vacuole; Bafilomycin; Hypoxia (environmental); Cell biology; Apoptosis; Programmed cell death; Biology; Lipopolysaccharide; PI3K/AKT/mTOR pathway; Chemistry; Immunology; Signal transduction; Biochemistry; Cytoplasm","score_opus":0.006266448762620069,"score_gpt":0.2548506543598151,"score_spread":0.24858420559719502,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2976218487","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99285823,0.0009129282,0.000008527573,0.00024229527,0.0011248512,0.0001345118,0.000017729128,0.000023395967,0.004677511],"genre_scores_gemma":[0.99793816,0.0004917248,0.000033444463,0.00013199841,0.0007678794,0.000016743572,0.000020786556,0.00001216784,0.0005871055],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998912,0.00003585696,0.0003757617,0.00015071509,0.00036122807,0.00016445067],"domain_scores_gemma":[0.99878335,0.0007278502,0.0001436376,0.00017777021,0.000114012015,0.0000533711],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035965166,0.000092942195,0.00019027614,0.00023622836,0.000020642054,0.00001062932,0.00014678492,0.000047157104,0.0007948422],"category_scores_gemma":[0.000280241,0.000068229936,0.00014643467,0.00021640208,0.000035642734,0.000068650355,0.000039086535,0.00014336547,0.00015342241],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053537276,0.00018168187,0.9758692,0.000013186086,0.000045042252,0.000017148299,0.00005866872,0.000005956448,0.0022145398,0.0015969487,0.00064639986,0.018815883],"study_design_scores_gemma":[0.0010899976,0.000121233184,0.9437234,0.00005250675,0.000051345076,0.000048462694,0.00013146523,0.0016017201,0.024518529,0.0052019805,0.023254238,0.00020515635],"about_ca_topic_score_codex":0.000040120456,"about_ca_topic_score_gemma":0.000001570846,"teacher_disagreement_score":0.03214581,"about_ca_system_score_codex":0.00005126682,"about_ca_system_score_gemma":0.0002348447,"threshold_uncertainty_score":0.8702964},"labels":[],"label_agreement":null},{"id":"W2977534155","doi":"10.1002/adtp.201900113","title":"A Drug‐Eluting 3D‐Printed Mesh (GlioMesh) for Management of Glioblastoma","year":2019,"lang":"en","type":"article","venue":"Advanced Therapeutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Queen's University; Research Institute in Oncology and Hematology; University of Manitoba; University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Temozolomide; Autophagy; PLGA; Drug; Glioblastoma; Drug delivery; Radiation therapy; Cancer research; Pharmacology; Chemotherapy; Medicine; In vitro; Chemistry; Materials science; Apoptosis; Surgery; Nanotechnology","score_opus":0.01322472512599167,"score_gpt":0.3055359233246362,"score_spread":0.29231119819864454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2977534155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98739547,0.0017719236,0.0037672827,0.0002477061,0.000314071,0.001486123,0.00001800054,0.00012952178,0.004869878],"genre_scores_gemma":[0.9847372,0.00046138675,0.010895745,0.0009176257,0.000045584176,0.00006102448,0.00001453023,0.000055284872,0.0028116293],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988291,0.000017294471,0.00032363614,0.00027583193,0.00023859859,0.00031551468],"domain_scores_gemma":[0.99905515,0.000082264574,0.00015999824,0.0004946991,0.00013272818,0.00007518907],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012134163,0.00018846054,0.00034980767,0.00011635611,0.000042623884,0.000006130543,0.00014415584,0.00005827291,0.00013116679],"category_scores_gemma":[0.0000036676943,0.00016750903,0.00017701996,0.00029300695,0.00004949933,0.00006984725,0.000041222567,0.00009880883,0.000042802916],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008207226,0.0012893609,0.0035535237,0.002214991,0.00383377,0.000063724074,0.0015026453,0.00043090965,0.20726584,0.042435355,0.000049028473,0.72915363],"study_design_scores_gemma":[0.028346848,0.0028992074,0.011784195,0.0016300133,0.0014132723,0.000042421685,0.0033483505,0.009075537,0.67573214,0.009115858,0.25560465,0.0010074794],"about_ca_topic_score_codex":9.176426e-7,"about_ca_topic_score_gemma":5.451615e-7,"teacher_disagreement_score":0.72814614,"about_ca_system_score_codex":0.00003656876,"about_ca_system_score_gemma":0.00003239892,"threshold_uncertainty_score":0.68308204},"labels":[],"label_agreement":null},{"id":"W2977710785","doi":"10.1158/0008-5472.can-19-1982","title":"MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"National Cancer Institute; National Institutes of Health; National Research Foundation of Korea; Ulsan National Institute of Science and Technology","keywords":"Cancer; Programmed cell death; Cancer research; Apoptosis; Biology; Medicine; Genetics","score_opus":0.07206351326378002,"score_gpt":0.42257754021877475,"score_spread":0.35051402695499473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2977710785","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882822,0.007082875,0.000014168913,0.00069545425,0.000221513,0.0007775318,0.000024293253,0.000011526942,0.0028904607],"genre_scores_gemma":[0.99090624,0.0008861984,0.000080484584,0.0002991566,0.0002741648,0.00017147073,0.000008955903,0.000024488245,0.0073488387],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985748,0.00009433303,0.00019012703,0.00025513023,0.00056331145,0.00032229218],"domain_scores_gemma":[0.9992562,0.00006401634,0.000043871307,0.00034088173,0.00020413364,0.000090880145],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022201666,0.000088724126,0.00022957579,0.00020819386,0.000028416189,0.000008285978,0.00012364378,0.00009378327,0.008122135],"category_scores_gemma":[0.000009576572,0.00007412954,0.00006715038,0.0004065651,0.00006433955,0.00006183369,0.000028557532,0.00027888184,0.00007499021],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017651326,0.0002526697,0.10564936,0.00031609164,0.000073699935,0.0000087028275,0.0013376086,0.00008537853,0.8834768,0.0003066424,0.002996689,0.003731242],"study_design_scores_gemma":[0.005046577,0.00040812677,0.17270577,0.00035848728,0.000025328989,9.971567e-7,0.00016142958,0.00089108135,0.8041747,0.002680159,0.01340454,0.00014279723],"about_ca_topic_score_codex":0.0012725178,"about_ca_topic_score_gemma":0.000041484313,"teacher_disagreement_score":0.07930208,"about_ca_system_score_codex":0.0002407295,"about_ca_system_score_gemma":0.0006607893,"threshold_uncertainty_score":0.99278456},"labels":[],"label_agreement":null},{"id":"W2978261599","doi":"10.1161/circ.128.suppl_22.a19154","title":"Abstract 19154: Maladaptive Autophagy and Necrotic Death of Ventricular Myocytes Induced by p53 is Contingent Upon Mitochondrial Death Gene Bnip3","year":2013,"lang":"en","type":"article","venue":"Circulation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autophagy; Medicine; Programmed cell death; Myocyte; Mitochondrion; Cell biology; Apoptosis; Gene; Cancer research; Internal medicine; Genetics; Biology","score_opus":0.02078647097976585,"score_gpt":0.25891593397029206,"score_spread":0.2381294629905262,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2978261599","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958692,0.0021719832,0.0004882,0.000118127115,0.00015791715,0.0009229427,0.000014771886,0.000044329183,0.00021250904],"genre_scores_gemma":[0.99908555,0.00004593566,0.0002673128,0.00020628484,0.00018826798,0.000046590732,0.00009858589,0.000025653055,0.00003582258],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988207,0.00003280873,0.00034824427,0.00029577082,0.00028298944,0.0002194719],"domain_scores_gemma":[0.9991795,0.00005100429,0.00021244299,0.00023872328,0.00016084909,0.00015746996],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007014161,0.00018134208,0.00031597746,0.000090406225,0.00007032913,0.000027442065,0.000055210003,0.0001543634,0.00043561315],"category_scores_gemma":[0.000049878337,0.00016636311,0.00010930651,0.000100104364,0.000025805268,0.0001603409,0.00001831213,0.00011533767,0.000037612313],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016221275,0.00034708064,0.09756775,0.00011531202,0.0003694682,0.00004153508,0.0005503456,0.0000406837,0.8945619,0.00047033187,0.00023186833,0.0055414964],"study_design_scores_gemma":[0.0019154224,0.00008676051,0.79856014,0.00007034234,0.00014794839,0.000016227132,0.00003576181,0.0018827677,0.19649003,0.0005917352,0.00006818891,0.00013468132],"about_ca_topic_score_codex":0.00026951227,"about_ca_topic_score_gemma":4.481269e-7,"teacher_disagreement_score":0.70099235,"about_ca_system_score_codex":0.00007815324,"about_ca_system_score_gemma":0.000065831744,"threshold_uncertainty_score":0.67840904},"labels":[],"label_agreement":null},{"id":"W2979601009","doi":"10.1038/s41564-019-0583-6","title":"Evasion of autophagy mediated by Rickettsia surface protein OmpB is critical for virulence","year":2019,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; NIH Office of the Director; U.S. Department of Health and Human Services; National Institutes of Health; Fonds de recherche du Québec – Nature et technologies; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Howard Hughes Medical Institute","keywords":"Autophagy; Cell biology; Biology; Microbiology; Intracellular parasite; Cytosol; Bacterial outer membrane; Intracellular; Gene; Apoptosis; Biochemistry; Escherichia coli","score_opus":0.005336277062289684,"score_gpt":0.2928231302015011,"score_spread":0.2874868531392114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2979601009","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9870234,0.008690845,0.00013379226,0.0018947896,0.00028033197,0.0011320838,0.00055085454,0.000055353827,0.00023851554],"genre_scores_gemma":[0.9937557,0.000048335678,0.001257223,0.003313275,0.00006142573,0.000020373527,0.00038151254,0.000026506572,0.0011356393],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988589,0.00006776667,0.00027839246,0.00038879327,0.00007902812,0.00032710953],"domain_scores_gemma":[0.9990154,0.0002603821,0.00009060275,0.00032571185,0.00021554639,0.00009236485],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017068652,0.00018444256,0.0004667153,0.000053701046,0.00003374875,0.0000034867364,0.00016301044,0.0007866655,0.0007955403],"category_scores_gemma":[0.00020282979,0.00014502849,0.00014900418,0.00013875135,0.00016584239,0.00003877238,0.000034962995,0.00043962777,0.00013235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065543473,0.00020185,0.0005911073,0.00020247011,0.0000774066,0.000005492822,0.000051710307,2.2450442e-7,0.98091054,0.00065866375,0.01644369,0.00020141681],"study_design_scores_gemma":[0.002367458,0.0007335004,0.0010137754,0.00011106666,0.000057183595,0.00003653498,0.000020449073,0.00007197338,0.9508997,0.0002970129,0.04423839,0.00015292587],"about_ca_topic_score_codex":0.000006615364,"about_ca_topic_score_gemma":4.5328056e-7,"teacher_disagreement_score":0.0300108,"about_ca_system_score_codex":0.0000378209,"about_ca_system_score_gemma":0.00011787663,"threshold_uncertainty_score":0.87106085},"labels":[],"label_agreement":null},{"id":"W2979792120","doi":"10.1002/1873-3468.13637","title":"Hijacking intracellular membranes to feed autophagosomal growth","year":2019,"lang":"en","type":"review","venue":"FEBS Letters","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Autophagosome; Autophagy; Endoplasmic reticulum; Cell biology; Golgi apparatus; Biogenesis; ATG16L1; Endosome; Intracellular; Lysosome; Biology; Cytosol; Organelle; Chemistry; Biochemistry; Apoptosis; Enzyme","score_opus":0.04049374497329315,"score_gpt":0.31825053030165074,"score_spread":0.27775678532835757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2979792120","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012923499,0.9931967,0.00010450722,0.0016778306,0.0010604416,0.0018664362,0.000032559536,0.00023294402,0.0005361906],"genre_scores_gemma":[0.00015525825,0.9845326,0.00033269764,0.011574832,0.0014935426,0.0001440549,0.00028673964,0.00019737522,0.0012828802],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99743205,0.00013072879,0.00063379353,0.0007325686,0.00047124343,0.00059959997],"domain_scores_gemma":[0.99839056,0.0001310554,0.00024947088,0.00082474767,0.000050267518,0.0003539047],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00017697603,0.00066908443,0.002229125,0.0004088989,0.00007947829,0.00006242478,0.00039920994,0.00034470847,0.00055150205],"category_scores_gemma":[0.000062740655,0.0005394117,0.0009391009,0.00043191054,0.000057294266,0.000086808446,0.000097575845,0.00058801536,0.0027886091],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012101927,0.00020782273,0.00002427305,0.072472155,0.0019243429,0.0022758215,0.00029488342,0.000003388161,0.0013859626,0.00031453813,0.016634407,0.9043414],"study_design_scores_gemma":[0.00061056,0.00009602147,0.000042437292,0.009156172,0.0021238215,0.00016230707,0.0000060866223,0.000003969214,0.00029293768,0.000007656194,0.98695725,0.0005407697],"about_ca_topic_score_codex":0.000023586454,"about_ca_topic_score_gemma":3.5439461e-7,"teacher_disagreement_score":0.97032285,"about_ca_system_score_codex":0.00020721665,"about_ca_system_score_gemma":0.00024197633,"threshold_uncertainty_score":0.99970573},"labels":[],"label_agreement":null},{"id":"W2980115594","doi":"10.1016/j.bbrc.2019.10.069","title":"Rab18 regulates lipolysis via Arf/GBF1 and adipose triglyceride lipase","year":2019,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Adipose triglyceride lipase; Lipid droplet; Brefeldin A; Lipolysis; Cell biology; Chemistry; GTPase; Lipase; Triolein; Adipose tissue; Lipid metabolism; Small GTPase; Golgi apparatus; Biochemistry; Enzyme; Biology; Endoplasmic reticulum; Signal transduction","score_opus":0.04518006851258779,"score_gpt":0.36935323062927083,"score_spread":0.32417316211668307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980115594","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9850041,0.0068534147,0.000006695003,0.006536382,0.000016289106,0.00041929475,0.00002027691,0.00005130411,0.0010922243],"genre_scores_gemma":[0.9937499,0.0039625354,0.0005689261,0.00025661997,0.00013913412,0.000058620386,0.00009349114,0.000018005852,0.0011527669],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859107,0.00014611374,0.00020970535,0.00033732297,0.00037551447,0.0003402655],"domain_scores_gemma":[0.99742675,0.0005917583,0.0000342756,0.001304281,0.00018959634,0.00045331407],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026828886,0.00014443157,0.00028935767,0.00011477413,0.00021375564,0.00004410442,0.00033289287,0.00012865927,0.000114585106],"category_scores_gemma":[0.00018575568,0.000110635076,0.00010075023,0.00044596798,0.00097594573,0.00007380481,0.00043260647,0.0005109984,0.0001378231],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003496868,0.00061835814,0.00044799296,0.00007301432,0.000109039865,0.0000029888358,0.00007950416,2.0518538e-8,0.97954273,0.0024102172,0.0010411665,0.015325302],"study_design_scores_gemma":[0.004004603,0.0012253083,0.046682198,0.00036572048,0.00024796618,0.00005409294,0.00022960898,0.005344667,0.89848596,0.011589844,0.03122994,0.00054011185],"about_ca_topic_score_codex":0.00008478735,"about_ca_topic_score_gemma":0.0000014611326,"teacher_disagreement_score":0.081056766,"about_ca_system_score_codex":0.000036028385,"about_ca_system_score_gemma":0.00007889344,"threshold_uncertainty_score":0.45115674},"labels":[],"label_agreement":null},{"id":"W2981654654","doi":"10.33594/000000172","title":"Autophagy: A Novel Mechanism Involved in the Anti-Inflammatory Abilities of Probiotics","year":2019,"lang":"en","type":"article","venue":"Cellular Physiology and Biochemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Agence Universitaire de la Francophonie; Agence Nationale de la Recherche; Université de Lille","keywords":"Autophagy; ATG16L1; Cytokine; Immune system; Inflammatory bowel disease; Inflammation; Proinflammatory cytokine; Biology; Colitis; Gut flora; Immunology; Interleukin 10; Secretion; Cell biology; Medicine; Disease; Apoptosis; Biochemistry; Pathology","score_opus":0.007219118645944368,"score_gpt":0.21465807229254863,"score_spread":0.20743895364660425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2981654654","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986404,0.0007710176,0.0000070952483,0.00007550677,0.000051500945,0.00024071903,0.0000076090105,0.000014034436,0.00019210172],"genre_scores_gemma":[0.99931204,0.000055949156,0.000059444323,0.0002526083,0.00006147332,0.000008155491,0.000042692383,0.000007827146,0.00019977981],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99938256,0.000023938925,0.00017423819,0.00019963022,0.00007605462,0.0001435777],"domain_scores_gemma":[0.9995088,0.00004769094,0.00006700964,0.000314752,0.000029807146,0.000031921758],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013215694,0.00011597147,0.00024284434,0.000022702221,0.000023219663,0.000002833843,0.000101404956,0.00016743163,0.00006614941],"category_scores_gemma":[0.00001411945,0.00007833624,0.00006789863,0.00006208037,0.00019255183,0.000017637336,0.000033457603,0.0001577518,0.0000055861224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008663848,0.00019795966,0.0019352034,0.00059788214,0.00004001456,0.000008439871,0.0002593511,9.16316e-7,0.99550813,0.0013356154,0.0000106638645,0.000019200324],"study_design_scores_gemma":[0.00096551504,0.000105203624,0.01515794,0.00006365562,0.000027986476,0.000009952064,0.00055172725,0.0001202904,0.98122084,0.0016565917,0.000038546594,0.000081765735],"about_ca_topic_score_codex":0.0000024475844,"about_ca_topic_score_gemma":1.2482015e-7,"teacher_disagreement_score":0.014287289,"about_ca_system_score_codex":0.000009605168,"about_ca_system_score_gemma":0.00007620457,"threshold_uncertainty_score":0.31944594},"labels":[],"label_agreement":null},{"id":"W2982338995","doi":"10.1038/s41419-019-2107-y","title":"The fungal metabolite chaetocin is a sensitizer for pro-apoptotic therapies in glioblastoma","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Novartis Pharma; Ministero dello Sviluppo Economico; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; Cancer Research UK; Ontario Ministry of Economic Development and Innovation; Wellcome Trust; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; National Institute for Health and Care Research; Massachusetts General Hospital; Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi; European Commission; Pfizer","keywords":"Apoptosis; Chemistry; Cancer research; DNA damage; Pharmacology; In vivo; Biochemistry; Biology; DNA","score_opus":0.009506125954275782,"score_gpt":0.25400206728736624,"score_spread":0.24449594133309047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2982338995","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9756023,0.02142028,0.00001722302,0.0010373757,0.000102227816,0.0012508006,0.00005075052,0.000034165954,0.00048487418],"genre_scores_gemma":[0.9916023,0.00078310625,0.000044466997,0.0036460392,0.00012089407,0.00012009015,0.000011105825,0.000024996078,0.0036470203],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990806,0.000033121487,0.00016172013,0.00026683786,0.0001490963,0.0003086083],"domain_scores_gemma":[0.9991037,0.00010312845,0.000042148433,0.0003056832,0.0000497399,0.00039554838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012479594,0.00016409175,0.00022205533,0.000055830445,0.00009825818,0.00003803851,0.000056867306,0.00004506735,0.00007008827],"category_scores_gemma":[0.000029536845,0.000103731516,0.00013311005,0.00008422508,0.000054650398,0.00005865889,0.000021413387,0.00008065204,0.00004314553],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.09187636,0.004502349,0.6937151,0.005436895,0.0015761202,0.0014259926,0.01315867,0.000026649392,0.047959264,0.036029875,0.017571678,0.08672105],"study_design_scores_gemma":[0.02903458,0.0016018874,0.7814234,0.00031947988,0.0011428343,0.00003560108,0.0018962228,0.008452826,0.038771655,0.0255605,0.110659845,0.0011011554],"about_ca_topic_score_codex":0.000005794347,"about_ca_topic_score_gemma":0.0000013072287,"teacher_disagreement_score":0.093088165,"about_ca_system_score_codex":0.000015346941,"about_ca_system_score_gemma":0.00014656405,"threshold_uncertainty_score":0.42300487},"labels":[],"label_agreement":null},{"id":"W2983011423","doi":"10.1080/15548627.2019.1687212","title":"STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I","year":2019,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Wuhan Science and Technology Project; National Natural Science Foundation of China","keywords":"Autophagy; Cell biology; Biology; BECN1; Kinase; BAG3; Phosphatidylinositol; Phosphorylation; Mechanistic target of rapamycin; PI3K/AKT/mTOR pathway; Biochemistry; Signal transduction","score_opus":0.02239960838647612,"score_gpt":0.2852133658614648,"score_spread":0.26281375747498864,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2983011423","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9718492,0.008070689,0.00078987435,0.0008732799,0.0011881852,0.0024174347,0.00005405863,0.00045637094,0.014300876],"genre_scores_gemma":[0.99004126,0.0004153608,0.0014144646,0.0022619613,0.00053558557,0.00012641831,0.00012461148,0.00015359478,0.004926731],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99500304,0.000256929,0.0014317661,0.0010495564,0.0011880511,0.0010706256],"domain_scores_gemma":[0.9960213,0.0005669857,0.0006972116,0.002013308,0.0003883835,0.0003128503],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00063996925,0.00076402654,0.0014328357,0.00018930456,0.00034602484,0.00009346492,0.0008196945,0.00038772682,0.0036345245],"category_scores_gemma":[0.00007572994,0.0005670278,0.0006715367,0.00073480664,0.00042272802,0.00046874446,0.00023995616,0.00070215965,0.0008756916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011262266,0.0018497508,0.0007585627,0.0006420739,0.00103648,0.00046764434,0.0042261733,0.00008406786,0.9253191,0.044762716,0.0064176433,0.013309579],"study_design_scores_gemma":[0.005794139,0.0009963377,0.049436815,0.00033841585,0.00025994197,0.00013944299,0.00052278285,0.001833173,0.8992005,0.0013256335,0.03955157,0.0006012307],"about_ca_topic_score_codex":0.00016118094,"about_ca_topic_score_gemma":0.000008572724,"teacher_disagreement_score":0.048678253,"about_ca_system_score_codex":0.00021778206,"about_ca_system_score_gemma":0.00052881136,"threshold_uncertainty_score":0.99990225},"labels":[],"label_agreement":null},{"id":"W2983133471","doi":"10.1101/825828","title":"Nix induced mitochondrial fission, mitophagy, and myocyte insulin resistance are abrogated by PKA phosphorylation","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Athabasca University; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"","keywords":"Mitophagy; Lipotoxicity; Mitochondrial fission; Autophagy; Biology; Cell biology; Insulin resistance; Myocyte; Mitochondrion; Phosphatidic acid; Internal medicine; Endocrinology; Insulin; Biochemistry; Phospholipid; Apoptosis","score_opus":0.010702052257566808,"score_gpt":0.23251328129095963,"score_spread":0.22181122903339281,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2983133471","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97890973,0.015881613,0.0001826178,0.0005021682,0.0019176559,0.001719774,0.0004269204,0.00043831597,0.000021201966],"genre_scores_gemma":[0.99515545,0.0016657148,0.0011515089,0.0006645258,0.00084171566,0.00018174574,0.0000070989195,0.00019381713,0.0001384137],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99651784,0.00015790679,0.00074221246,0.0013755794,0.0006324447,0.00057401607],"domain_scores_gemma":[0.9964962,0.00008392324,0.00075060123,0.0015367259,0.00058358145,0.00054894487],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025037548,0.0007573369,0.0010065973,0.00025137892,0.00019370072,0.00015841033,0.00033850296,0.0011192821,0.00012807382],"category_scores_gemma":[0.00029381117,0.0007676591,0.00020166983,0.00046432682,0.00012712917,0.00017287792,0.00026551422,0.0011163673,0.0001041906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012707625,0.0003578734,0.008011993,0.0009182758,0.00044781977,0.00014562778,0.000029745233,0.0000057482002,0.97871035,0.000056733767,0.010037276,0.000007820897],"study_design_scores_gemma":[0.004774573,0.00013500237,0.24650347,0.0017351526,0.00033904103,4.3855618e-8,0.000008007602,0.00018135991,0.7295576,0.000007774109,0.015778124,0.0009799036],"about_ca_topic_score_codex":0.000039742285,"about_ca_topic_score_gemma":0.0000019230354,"teacher_disagreement_score":0.24915276,"about_ca_system_score_codex":0.0003347653,"about_ca_system_score_gemma":0.00076128513,"threshold_uncertainty_score":0.99947745},"labels":[],"label_agreement":null},{"id":"W2983388081","doi":"10.3390/nu11112824","title":"Exercise Mitigates the Loss of Muscle Mass by Attenuating the Activation of Autophagy during Severe Energy Deficit","year":2019,"lang":"en","type":"article","venue":"Nutrients","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Agencia Canaria de Investigación, Innovación y Sociedad de la Información; Universidad de Las Palmas de Gran Canaria; Ministerio de Economía y Competitividad","keywords":"Autophagy; Endocrinology; Internal medicine; AMPK; ULK1; Skeletal muscle; Anabolism; Sarcopenia; mTORC1; Catabolism; Protein degradation; Lysosome; Proteasome; Protein catabolism; Medicine; Chemistry; Biology; PI3K/AKT/mTOR pathway; Signal transduction; Cell biology; Phosphorylation; Protein kinase A; Metabolism; Biochemistry; Apoptosis","score_opus":0.005767153080048047,"score_gpt":0.22401994981173554,"score_spread":0.2182527967316875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2983388081","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99811685,0.0006990856,0.00003480679,0.00020222753,0.00007835717,0.00027710816,0.000018230034,0.000018302402,0.00055501703],"genre_scores_gemma":[0.9987125,0.00016206359,0.00002468744,0.00013894458,0.00003730578,0.00001988084,0.000023399682,0.000017946082,0.00086329004],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908745,0.000038089802,0.00024006341,0.00014723369,0.0003140251,0.00017315423],"domain_scores_gemma":[0.99920726,0.00009899392,0.00020156642,0.0003617658,0.000092302434,0.000038107715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001089028,0.000104628234,0.0002024674,0.000033372075,0.00007561391,0.0000060436364,0.00015193678,0.00006004627,0.00013721909],"category_scores_gemma":[0.000028083796,0.00006192401,0.000092588416,0.0001798836,0.00006903859,0.0000705177,0.000034448098,0.00008815102,0.0000112178195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00088035356,0.00062192726,0.1044848,0.00048691273,0.00026250092,0.00000664964,0.0018307907,0.0001295237,0.87939405,0.0011001141,0.0007835154,0.010018866],"study_design_scores_gemma":[0.0022214674,0.00008063731,0.10392574,0.00043659308,0.000067979505,0.0000027561932,0.00052530394,0.00028996487,0.8912943,0.0004946404,0.00057618174,0.00008444711],"about_ca_topic_score_codex":0.000056689296,"about_ca_topic_score_gemma":2.4345294e-7,"teacher_disagreement_score":0.011900229,"about_ca_system_score_codex":0.000026752014,"about_ca_system_score_gemma":0.00003226641,"threshold_uncertainty_score":0.2525188},"labels":[],"label_agreement":null},{"id":"W2987056530","doi":"10.1101/260257","title":"Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Society of Nephrology; University of Toronto; Jewish General Hospital; McGill University; Toronto Metropolitan University","funders":"Uppsala Multidisciplinary Center for Advanced Computational Science; Vetenskapsrådet; National Institutes of Health; Science for Life Laboratory; Hospital for Sick Children; Knut och Alice Wallenbergs Stiftelse","keywords":"TFEB; Phagocytosis; Phagocyte; Antigen presentation; Lysosome; Translation (biology); Endosome; Organelle; Biogenesis; Antigen processing","score_opus":0.016345888833795563,"score_gpt":0.2570724797266408,"score_spread":0.24072659089284526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2987056530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945507,0.0012999739,0.0013244345,0.00046694605,0.00033198606,0.0016789902,0.00004310963,0.0002870619,0.00001679444],"genre_scores_gemma":[0.99661493,0.00091745914,0.0009578606,0.00014474397,0.00096216437,0.0002898726,0.0000016607181,0.00009562234,0.000015676915],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979368,0.00012844338,0.00043329754,0.00071967556,0.00042682703,0.00035494915],"domain_scores_gemma":[0.99822813,0.00012737919,0.00036286382,0.0007867064,0.00031922714,0.00017566305],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000298063,0.0004192476,0.0004293877,0.00014414378,0.00027706145,0.00014129787,0.00018875586,0.00034916046,0.00009117173],"category_scores_gemma":[0.00016324769,0.00034802628,0.00012869047,0.00028658847,0.00015568215,0.00026804302,0.000096957425,0.00043534732,0.000015861939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003245529,0.00011927701,0.0022955448,0.00049404573,0.00028995328,0.0000111038335,0.0001432835,0.0000051446104,0.9962618,0.00002467728,0.000012116592,0.000018537537],"study_design_scores_gemma":[0.0011902336,0.000063837775,0.31969747,0.00033677637,0.00014512241,3.3668847e-8,0.000005631002,0.00019672628,0.6780395,0.000007291432,0.0000803632,0.00023702957],"about_ca_topic_score_codex":0.000020045984,"about_ca_topic_score_gemma":6.9261193e-7,"teacher_disagreement_score":0.31822225,"about_ca_system_score_codex":0.00014927382,"about_ca_system_score_gemma":0.00028994633,"threshold_uncertainty_score":0.9998972},"labels":[],"label_agreement":null},{"id":"W2987089172","doi":"10.7554/elife.14810.026","title":"Author response: Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain","year":2016,"lang":"en","type":"peer-review","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"","keywords":"Autophagy; Forebrain; Neuroscience; Biology; Axon; Axon guidance; Microglia; Cell biology; Central nervous system; Genetics; Inflammation; Immunology; Apoptosis","score_opus":0.07175284944836359,"score_gpt":0.38497353472619705,"score_spread":0.3132206852778335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2987089172","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.013918525,0.018511297,0.0010837681,0.9492683,0.0028711776,0.006539912,0.002454806,0.00029018655,0.00506203],"genre_scores_gemma":[0.010780898,0.000905982,0.0005225164,0.16825595,0.0024472564,0.0012908857,0.0010054385,0.00023411517,0.81455696],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9941574,0.0013749922,0.0011081571,0.0012519171,0.0011318341,0.00097572984],"domain_scores_gemma":[0.9914528,0.0055007255,0.0005267455,0.0017804417,0.00039383429,0.00034544955],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0056913127,0.00081923517,0.0016533786,0.00038568766,0.00024488606,0.00011811559,0.00086578896,0.0008033587,0.0037554954],"category_scores_gemma":[0.0061843526,0.00049701054,0.00088481506,0.0005303397,0.00021664701,0.0002985587,0.00014240072,0.0010607726,0.00013589216],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027810892,0.00027137098,0.000022352384,0.0018401325,0.00021440687,0.00025685373,0.0003964276,9.818234e-8,0.00077926356,0.0012040064,0.97801065,0.014223334],"study_design_scores_gemma":[0.0038212796,0.00074322737,0.00431287,0.004205603,0.00051317934,0.000092602284,0.00006331845,0.000061956795,0.00058821624,0.0013527632,0.9836646,0.0005804201],"about_ca_topic_score_codex":0.00020734292,"about_ca_topic_score_gemma":0.0001127392,"teacher_disagreement_score":0.8094949,"about_ca_system_score_codex":0.00029742112,"about_ca_system_score_gemma":0.0015619625,"threshold_uncertainty_score":0.9997482},"labels":[],"label_agreement":null},{"id":"W2987106274","doi":"10.1007/s12576-019-00720-6","title":"Cross talk between 26S proteasome and mitochondria in human mesenchymal stem cells’ ability to survive under hypoxia stress","year":2019,"lang":"en","type":"article","venue":"The Journal of Physiological Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Yarmouk University","keywords":"Mesenchymal stem cell; Proteasome; Hypoxia (environmental); Cell biology; Stem cell; Mitochondrion; Biology; Transplantation; Immunology; Medicine; Chemistry; Internal medicine","score_opus":0.047272803231987064,"score_gpt":0.34278015211526675,"score_spread":0.2955073488832797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2987106274","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987315,0.00018387467,0.000010981925,0.0004303348,0.000097692566,0.00041888416,0.0000065109466,0.0000063749812,0.000113848706],"genre_scores_gemma":[0.99946225,0.000017386003,0.00006299329,0.00018754687,0.00017041063,0.0000025326399,3.3833513e-7,0.000003183688,0.00009335562],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985658,0.00026293323,0.00032844915,0.00019063072,0.00040262484,0.00024957227],"domain_scores_gemma":[0.99915934,0.0002624293,0.00017768495,0.00015265332,0.0000735564,0.00017431365],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010617215,0.000117938034,0.00035803372,0.00005270349,0.00014060838,0.000035251214,0.00035794376,0.00006199547,0.00017599392],"category_scores_gemma":[0.000028877179,0.000053814016,0.00007708735,0.0002629293,0.0005335381,0.00014390309,0.000095288065,0.0002574854,0.0000092321425],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033440758,0.00023656759,0.14612414,0.00003476807,0.000032841843,0.000011813096,0.00051177386,0.00076725445,0.8508312,0.00018904467,0.000024262952,0.000901932],"study_design_scores_gemma":[0.00059950264,0.0016954561,0.96823335,0.00007206231,0.000017323044,0.000007132472,0.0005334599,0.000025674499,0.02467511,0.004048048,0.000012926825,0.00007995478],"about_ca_topic_score_codex":0.00005612033,"about_ca_topic_score_gemma":0.0000054203265,"teacher_disagreement_score":0.8261561,"about_ca_system_score_codex":0.000035200734,"about_ca_system_score_gemma":0.000061924184,"threshold_uncertainty_score":0.21944718},"labels":[],"label_agreement":null},{"id":"W2988576576","doi":"10.3390/cancers11111775","title":"Molecular Mechanisms Underlying Autophagy-Mediated Treatment Resistance in Cancer","year":2019,"lang":"en","type":"review","venue":"Cancers","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Simon Fraser University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; PI3K/AKT/mTOR pathway; Context (archaeology); Signal transduction; Protein kinase B; Cancer; Mechanism (biology); Biology; Cancer research; Bioinformatics; Medicine; Cell biology; Apoptosis; Genetics","score_opus":0.09693929159505704,"score_gpt":0.39845491922881754,"score_spread":0.3015156276337605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2988576576","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00020246184,0.9950638,0.000049743896,0.00003845635,0.00059442787,0.0018531585,0.0001471787,0.00008995178,0.0019608669],"genre_scores_gemma":[0.00038488998,0.99443483,0.000110236026,0.00040910486,0.00006769451,0.0010320966,0.00024655112,0.00012894091,0.0031856324],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99796,0.00009286043,0.0005134103,0.0006581712,0.00029477463,0.00048081917],"domain_scores_gemma":[0.9987558,0.00008064705,0.00027614846,0.00064270134,0.000038853577,0.00020582962],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008084069,0.00055565184,0.0020179015,0.00026619728,0.00003762311,0.000017557986,0.00017865808,0.00037036475,0.0004105161],"category_scores_gemma":[0.000016780346,0.00044307485,0.0005505593,0.00051205984,0.00005022592,0.000043761425,0.000020659694,0.00030669748,0.00013392228],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":true,"study_design_scores_codex":[0.00019110648,0.00016516964,0.000004538156,0.03037614,0.002354346,0.002045852,0.00032600862,0.00009958139,0.0001025364,0.00246317,0.00064321543,0.9612283],"study_design_scores_gemma":[0.001813198,0.00016869116,0.000017329117,0.02179431,0.0016777706,0.0000077992545,0.00002582806,0.000034312907,0.00008825422,0.00024087996,0.97366256,0.0004690751],"about_ca_topic_score_codex":0.00034992487,"about_ca_topic_score_gemma":0.00018026317,"teacher_disagreement_score":0.97301936,"about_ca_system_score_codex":0.009693263,"about_ca_system_score_gemma":0.0059173787,"threshold_uncertainty_score":0.9998021},"labels":[],"label_agreement":null},{"id":"W2988924633","doi":"10.1007/s42978-019-00041-5","title":"Mitophagy Regulation in Skeletal Muscle: Effect of Endurance Exercise and Age","year":2019,"lang":"en","type":"article","venue":"Journal of Science in Sport and Exercise","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mitophagy; Mitochondrion; Skeletal muscle; Cell biology; Mitochondrial biogenesis; Organelle; Organelle biogenesis; Biology; Biogenesis; Endocrinology; Internal medicine; Medicine; Autophagy; Biochemistry; Gene","score_opus":0.00519819438332918,"score_gpt":0.2610381106252957,"score_spread":0.2558399162419665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2988924633","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965557,0.0028116372,0.0000013307035,0.000032872547,0.00018741928,0.00024443454,4.2949188e-7,0.0000024279325,0.00016373614],"genre_scores_gemma":[0.99760306,0.002094258,0.00014548683,0.000015465923,0.00003161054,0.00000184725,5.3533745e-7,0.0000051755387,0.00010258915],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99892706,0.0000056121976,0.00038809172,0.0001504607,0.0003663641,0.00016243916],"domain_scores_gemma":[0.99946976,0.000019812722,0.00020373822,0.0001237451,0.000059339865,0.0001236257],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00096259214,0.00009385212,0.0004666137,0.0003947818,0.000023852806,0.000011291283,0.00008858009,0.000043212814,0.000039323855],"category_scores_gemma":[0.000018091847,0.00006794446,0.000050351355,0.00044835176,0.00035329864,0.00040671247,0.00002192973,0.0001439706,0.0000012855481],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00077774766,0.00011967213,0.8787259,0.00021393367,0.0000030592453,0.00034191442,0.0010502249,0.00002526455,0.04023759,0.000024460813,0.00001388306,0.078466386],"study_design_scores_gemma":[0.002079463,0.00025346887,0.9811368,0.0012584045,0.00002317525,0.000058522663,0.00015935814,0.00016794237,0.014605096,0.00014257341,0.0000521694,0.00006305208],"about_ca_topic_score_codex":0.000024617952,"about_ca_topic_score_gemma":0.0000022159963,"teacher_disagreement_score":0.102410905,"about_ca_system_score_codex":0.000030211595,"about_ca_system_score_gemma":0.00008869543,"threshold_uncertainty_score":0.27706945},"labels":[],"label_agreement":null},{"id":"W2989574239","doi":"10.1165/rcmb.2019-0157le","title":"Altered Calcium in Ciliary Dysfunction: Potential Role of Endoplasmic Reticulum Stress and Ciliophagy","year":2019,"lang":"en","type":"letter","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Endoplasmic reticulum; Calcium; Cell biology; Medicine; Calcium signaling; Biology; Internal medicine; Endocrinology","score_opus":0.005325161080071501,"score_gpt":0.24261147984712414,"score_spread":0.23728631876705264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2989574239","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97587055,0.0186159,0.00017156161,0.0046216436,0.0003184048,0.00019920102,0.00004429416,0.0000047917633,0.00015364509],"genre_scores_gemma":[0.877829,0.00095755776,0.00011935163,0.12016521,0.0007955615,0.0000045560496,0.000033994533,0.000039417395,0.000055341236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982341,0.00036647214,0.0006086723,0.00031484402,0.00019319064,0.00028274732],"domain_scores_gemma":[0.99865425,0.00006950813,0.000750719,0.00026532504,0.0001450023,0.00011518454],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017718454,0.00027509357,0.0009782888,0.00041452513,0.000020303782,0.0000072261078,0.00012642915,0.00029700494,0.000039189697],"category_scores_gemma":[0.000023354703,0.00022538811,0.00020035518,0.00013517767,0.00058131636,0.000028999842,0.00005492134,0.00096994237,0.00000181422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021088936,0.0002680338,0.01599164,0.0006823564,0.0008289668,0.0059459414,0.00019090477,0.000018679913,0.94448686,0.000014584468,0.010776644,0.018686509],"study_design_scores_gemma":[0.0116607165,0.020601163,0.009249625,0.0008910675,0.0012813372,0.0020068337,0.0008766399,0.000048036756,0.6246848,0.00052249414,0.32720518,0.0009721182],"about_ca_topic_score_codex":0.000036320547,"about_ca_topic_score_gemma":7.909825e-7,"teacher_disagreement_score":0.31980208,"about_ca_system_score_codex":0.000026318714,"about_ca_system_score_gemma":0.00029098344,"threshold_uncertainty_score":0.91910607},"labels":[],"label_agreement":null},{"id":"W2989984439","doi":"10.1080/15548627.2019.1689770","title":"Restriction of intracellular <i>Salmonella</i> replication by restoring TFEB-mediated xenophagy","year":2019,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Wellcome Trust","keywords":"TFEB; Biology; Autophagy; Vacuole; Cell biology; LAMP1; Wortmannin; Endosome; Lysosome; Biochemistry; Intracellular parasite; PI3K/AKT/mTOR pathway; Intracellular; Signal transduction; Cytoplasm","score_opus":0.007168102781741063,"score_gpt":0.24639475709732903,"score_spread":0.23922665431558796,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2989984439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98998666,0.004152395,0.0001969969,0.0002831713,0.00037694495,0.00057106314,0.000019675952,0.0001944495,0.004218663],"genre_scores_gemma":[0.9944947,0.00079939334,0.00020745335,0.00042602234,0.00014035989,0.000030130599,0.0002439166,0.000047886813,0.0036101572],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983053,0.0000569252,0.00047414194,0.00048692655,0.00039552743,0.00028118162],"domain_scores_gemma":[0.9982285,0.000100314646,0.00025645192,0.0010791996,0.00012803044,0.00020750183],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026652258,0.00019009887,0.00037903403,0.0001377879,0.000047421334,0.000010188209,0.00014484013,0.00018726589,0.00039329688],"category_scores_gemma":[0.00017548783,0.00018463448,0.00012082139,0.00042469005,0.00005391069,0.00013439689,0.000032487875,0.00020957529,0.00037764123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027727665,0.00030669456,0.0053654206,0.0001090018,0.000100444675,0.00002662354,0.000113758986,0.000016108504,0.9839111,0.0007488497,0.005678879,0.0033458387],"study_design_scores_gemma":[0.002233275,0.0005344447,0.025950024,0.00009075668,0.00009752367,0.00002348858,0.00004869411,0.0007325116,0.9372883,0.00035019437,0.032441843,0.0002089422],"about_ca_topic_score_codex":0.00008869306,"about_ca_topic_score_gemma":3.059703e-7,"teacher_disagreement_score":0.0466228,"about_ca_system_score_codex":0.00010162177,"about_ca_system_score_gemma":0.00013717181,"threshold_uncertainty_score":0.7529176},"labels":[],"label_agreement":null},{"id":"W2990412002","doi":"10.1186/s13024-019-0342-4","title":"Autophagy protein NRBF2 has reduced expression in Alzheimer’s brains and modulates memory and amyloid-beta homeostasis in mice","year":2019,"lang":"en","type":"article","venue":"Molecular Neurodegeneration","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health; Fundo para o Desenvolvimento das Ciências e da Tecnologia","keywords":"Autophagy; BECN1; Hippocampus; Downregulation and upregulation; Amyloid beta; Neuroscience; ULK1; Long-term potentiation; Cell biology; Biology; Amyloid precursor protein; Alzheimer's disease; Medicine; Kinase; Protein kinase A; Gene; Disease; Internal medicine; Genetics","score_opus":0.018063553249972192,"score_gpt":0.25341418921701003,"score_spread":0.23535063596703784,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2990412002","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922765,0.0053920313,0.00008573338,0.00092700275,0.000065765176,0.0011046304,0.000004323036,0.000038634276,0.000105386156],"genre_scores_gemma":[0.99840665,0.00011953494,0.00046437507,0.00073606573,0.000033984394,0.00006299304,0.00005163497,0.000038395694,0.00008638338],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986612,0.0001584608,0.00027575777,0.0004894978,0.00020051483,0.00021453617],"domain_scores_gemma":[0.9995073,0.000017243632,0.00006835866,0.00027352618,0.000030884035,0.00010269991],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014343573,0.00019527013,0.00026938625,0.00022573044,0.00004742172,0.000051392926,0.000053295338,0.00011845924,0.000030464967],"category_scores_gemma":[0.000029105668,0.00018951035,0.000037710295,0.00019109667,0.000047207883,0.0001595277,0.00004607306,0.00017240703,0.0000072566686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015382846,0.00011059089,0.00059009943,0.000042531003,0.000018624336,0.00011590396,0.0003414662,0.0002839863,0.99254036,0.00008137273,0.000019612948,0.00570162],"study_design_scores_gemma":[0.0021956547,0.00017391914,0.034924768,0.000107971566,0.000030410287,0.00001921805,0.00002895493,0.006922188,0.9552605,0.000114156544,0.00005545553,0.00016681351],"about_ca_topic_score_codex":0.000063007545,"about_ca_topic_score_gemma":0.000019903471,"teacher_disagreement_score":0.037279874,"about_ca_system_score_codex":0.00002531619,"about_ca_system_score_gemma":0.000064641616,"threshold_uncertainty_score":0.7728008},"labels":[],"label_agreement":null},{"id":"W2990730777","doi":"10.1038/s41592-019-0661-y","title":"An antibody for analysis of autophagy induction","year":2019,"lang":"en","type":"article","venue":"Nature Methods","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; Institute of Infection and Immunity; Université Laval; University of Ottawa","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Autophagy; ATG16L1; Cell biology; Biology; ULK1; Western blot; BAG3; Phosphorylation; Monoclonal antibody; Autophagy-related protein 13; Antibody; Protein phosphorylation; Immunology; Biochemistry; Protein kinase A; Gene; Apoptosis","score_opus":0.023597616612049704,"score_gpt":0.4989560977898662,"score_spread":0.47535848117781654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2990730777","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.938977,0.0014709735,0.05771599,0.00008364352,0.0004797186,0.00038680364,0.000021221802,0.000048424314,0.0008162004],"genre_scores_gemma":[0.83445317,0.000022427424,0.1642864,0.0004448058,0.0001376046,0.000008951319,0.00018916864,0.000014854632,0.00044261967],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917406,0.00013623571,0.00018290152,0.00023158656,0.0001496888,0.00012553389],"domain_scores_gemma":[0.99908304,0.0001372159,0.000102713486,0.0004481246,0.00015397022,0.00007493308],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067186635,0.00009723092,0.0004398285,0.0003462282,0.000021554431,0.0000049847245,0.00008197467,0.0003245266,0.00036862292],"category_scores_gemma":[0.000099467376,0.00007655491,0.00028135584,0.0007489133,0.000022878776,0.00007166795,0.000007030096,0.00024087973,0.0000026326134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000492259,0.0002827385,0.01048602,0.00009915636,0.0022313674,0.0000022749787,0.0002072231,0.00006342413,0.90531725,0.0039198315,0.000079384285,0.0768191],"study_design_scores_gemma":[0.0015294842,0.00065324455,0.44338876,0.000022409502,0.0033777093,0.0000042277866,0.00009352241,0.011659702,0.5291542,0.0014682172,0.008499887,0.00014863687],"about_ca_topic_score_codex":0.000006216856,"about_ca_topic_score_gemma":4.768368e-7,"teacher_disagreement_score":0.43290272,"about_ca_system_score_codex":0.00002086426,"about_ca_system_score_gemma":0.000052576124,"threshold_uncertainty_score":0.40361625},"labels":[],"label_agreement":null},{"id":"W2990870824","doi":"10.1038/s41419-019-2132-x","title":"Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Occupational Cancer Research Centre; McGill University; University Health Network; University of Toronto; Montreal Neurological Institute and Hospital; Toronto Western Hospital; Canada Research Chairs","funders":"Canadian Institutes of Health Research; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Mitophagy; Parkin; Cell biology; Programmed cell death; Apoptosis; Cancer research; Autophagy; Biology; Chemistry; Genetics; Medicine","score_opus":0.009167255125084981,"score_gpt":0.22878723335323706,"score_spread":0.21961997822815207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2990870824","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9616383,0.032935448,0.000008772954,0.0001240281,0.00018128294,0.0006044962,0.00007569226,0.000099480116,0.0043325396],"genre_scores_gemma":[0.9830471,0.0023472838,0.00005994345,0.00117283,0.00013571272,0.000027852202,0.00015369503,0.00004820882,0.013007357],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99835247,0.00006228939,0.00026100595,0.0005683015,0.0003052529,0.00045069543],"domain_scores_gemma":[0.9979349,0.000068714304,0.00010562852,0.00045211008,0.00006719922,0.001371465],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011634211,0.0003170029,0.00040093687,0.00009464088,0.00012659728,0.00005579119,0.000091799775,0.00013823954,0.00048155343],"category_scores_gemma":[0.000035894034,0.0002699434,0.00014817192,0.000091094145,0.00005258055,0.00009938799,0.00007682824,0.00013787489,0.00014284815],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018085884,0.0016268794,0.9491867,0.00074649137,0.00022982848,0.0010080239,0.00026644967,0.000008532674,0.041502386,0.00031112813,0.0016400021,0.0016650009],"study_design_scores_gemma":[0.011009631,0.0005255345,0.93219006,0.00018211418,0.00094038015,0.000017995588,0.00011495258,0.00085391186,0.047102615,0.0029141179,0.003483262,0.0006654361],"about_ca_topic_score_codex":0.000029531016,"about_ca_topic_score_gemma":0.000001110667,"teacher_disagreement_score":0.030588167,"about_ca_system_score_codex":0.000045502464,"about_ca_system_score_gemma":0.00019205973,"threshold_uncertainty_score":0.99997526},"labels":[],"label_agreement":null},{"id":"W2991037919","doi":"10.1128/jvi.01936-19","title":"Hepatitis Delta Virus Alters the Autophagy Process To Promote Its Genome Replication","year":2019,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Biology; Virology; Hepatitis B virus; Coinfection; HBsAg; Virus; Hepatitis D virus; Viral replication; Hepatitis D; Viral life cycle; Autophagy; Genetics; Apoptosis","score_opus":0.012890921562906716,"score_gpt":0.30874573344781664,"score_spread":0.2958548118849099,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2991037919","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992055,0.0009417203,0.0002454811,0.0057353103,0.0002444275,0.0004253604,0.0000057294756,0.000013125625,0.00033384992],"genre_scores_gemma":[0.99191016,0.0003344199,0.00013810188,0.006840126,0.00032395704,0.000011726549,0.0000038141247,0.000017502738,0.0004201756],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99901354,0.000057641802,0.00036386494,0.0001647471,0.00021556171,0.00018464107],"domain_scores_gemma":[0.9989519,0.00003546505,0.00029360273,0.00037613258,0.00019946512,0.00014345028],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036685728,0.00009944921,0.00027599747,0.00010551289,0.000045439276,0.000009529625,0.00021705592,0.00007770122,0.0004187643],"category_scores_gemma":[0.00009347391,0.00006271069,0.0001015329,0.00013958804,0.000031310028,0.00008688836,0.000022686076,0.0002261747,0.00018950865],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002187268,0.00047031316,0.009576293,0.0000993413,0.0005120252,0.00028673018,0.0023521131,0.00047210325,0.9668608,0.00021816992,0.0015613034,0.01540354],"study_design_scores_gemma":[0.004080103,0.007020414,0.744523,0.000110580884,0.00035574887,0.0025436163,0.000097806085,0.001268751,0.18566327,0.0019218716,0.052142598,0.00027221988],"about_ca_topic_score_codex":0.000008782813,"about_ca_topic_score_gemma":0.000002240365,"teacher_disagreement_score":0.78119755,"about_ca_system_score_codex":0.00005150866,"about_ca_system_score_gemma":0.00013744456,"threshold_uncertainty_score":0.45851755},"labels":[],"label_agreement":null},{"id":"W2992428617","doi":"","title":"Dysregulated autophagy contributes to pathological angiogenesis in a mice model of retinal angiomatous proliferation. Heckel E, Pundir S, Patel G, Kim JS, Lacombe MJ, Saba N, Fredrick T, Sun Y, Smith LEH, Joyal JS","year":2016,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Autophagy; Retinal; Pathological; Angiogenesis; Anatomy; Biology; Medicine; Pathology; Ophthalmology; Cancer research; Genetics; Apoptosis","score_opus":0.0369823111468198,"score_gpt":0.3271176169649182,"score_spread":0.2901353058180984,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2992428617","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958537,0.0006515205,0.00033889536,0.0015080253,0.00013634525,0.00109552,0.00011152411,0.00009881711,0.00020560929],"genre_scores_gemma":[0.9958781,0.000015633866,0.00263178,0.0007902038,0.000056001234,0.00017088595,0.00001607648,0.00003162683,0.00040970554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9961272,0.00037546668,0.0008324548,0.0010636674,0.0006761515,0.000925054],"domain_scores_gemma":[0.99774915,0.00028473826,0.00031524844,0.0004206498,0.0006047865,0.00062541134],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0011414824,0.00043468815,0.0008610923,0.0005689829,0.00024399848,0.000033478493,0.0005501747,0.00032062264,0.00010276426],"category_scores_gemma":[0.0012294737,0.0002995965,0.00017762622,0.0017216994,0.0041465177,0.00032344705,0.00025735967,0.00020329002,0.00004776603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005031444,0.0006230279,0.15915051,0.00002250591,0.00006194741,0.00064760767,0.0005558992,0.00010699468,0.8374078,0.0005647066,0.000099039455,0.0002568019],"study_design_scores_gemma":[0.0016814277,0.0010328945,0.46019325,0.00019039251,0.00004478322,0.00033140203,0.00006274143,0.002079422,0.5300317,0.004110782,0.0000035774274,0.00023767444],"about_ca_topic_score_codex":0.00011768376,"about_ca_topic_score_gemma":0.000004807278,"teacher_disagreement_score":0.30737615,"about_ca_system_score_codex":0.00029578686,"about_ca_system_score_gemma":0.0011976023,"threshold_uncertainty_score":0.99994564},"labels":[],"label_agreement":null},{"id":"W2992507057","doi":"10.1139/bcb-2019-0333","title":"Active vitamin D activates chondrocyte autophagy to reduce osteoarthritis via mediating the AMPK–mTOR signaling pathway","year":2019,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":58,"is_retracted":true,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autophagy; AMPK; PI3K/AKT/mTOR pathway; Chondrocyte; Chemistry; Osteoarthritis; Endocrinology; Inflammation; Internal medicine; Signal transduction; Pharmacology; Cartilage; Cancer research; Medicine; Protein kinase A; Kinase; Apoptosis; Biochemistry; Pathology; Anatomy","score_opus":0.006155038650211813,"score_gpt":0.23533418992243896,"score_spread":0.22917915127222716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2992507057","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948794,0.0017364934,0.000022716464,0.00037505463,0.00023956508,0.00036508706,0.000042170646,0.00004816644,0.0022912945],"genre_scores_gemma":[0.99670523,0.00007330684,0.00013430648,0.00080887676,0.00041032096,0.000052015723,0.00009612579,0.000019023695,0.0017007838],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989363,0.000049010127,0.0001987498,0.00041570864,0.00008820198,0.0003120591],"domain_scores_gemma":[0.999175,0.0001519664,0.00010033824,0.00034252653,0.00004851308,0.00018166586],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010985303,0.00020223309,0.00027677222,0.00002725439,0.00011533212,0.000013812379,0.00015536549,0.00022063014,0.00030449335],"category_scores_gemma":[0.000065005646,0.00014498169,0.00008102713,0.00010966268,0.00010559746,0.000031760614,0.00009792328,0.00021996305,0.000065083965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003278126,0.000052506763,0.0002471524,0.000059906677,0.000041060528,0.000012644049,0.00028460682,6.150768e-7,0.9668658,0.000009416319,0.000058591282,0.032039892],"study_design_scores_gemma":[0.0012276142,0.00037289655,0.00049208873,0.000049743634,0.000027464741,0.00003165218,0.0004902833,0.000017620596,0.99339914,0.00007614192,0.0036443314,0.0001710409],"about_ca_topic_score_codex":0.0000113549495,"about_ca_topic_score_gemma":2.6450178e-7,"teacher_disagreement_score":0.031868853,"about_ca_system_score_codex":0.000035773333,"about_ca_system_score_gemma":0.00009404891,"threshold_uncertainty_score":0.5912182},"labels":[],"label_agreement":null},{"id":"W2995327781","doi":"10.21769/bioprotoc.3455","title":"Lysosome Targeting RedGreen-assay: Selective Autophagy Sensing Assay for Mammalian Cells","year":2019,"lang":"en","type":"article","venue":"BIO-PROTOCOL","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Autophagosome; Cell biology; Organelle; Lysosome; Green fluorescent protein; mCherry; Biology; ATG8; Chemistry; Biochemistry","score_opus":0.015477134458172266,"score_gpt":0.3118249865332434,"score_spread":0.29634785207507114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2995327781","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.02635119,0.000018282948,0.0017846351,0.00044121224,0.0003823884,0.9624693,0.00005128618,0.00041949833,0.008082221],"genre_scores_gemma":[0.16002804,6.5925775e-7,0.010202572,0.0017346423,0.0014600485,0.8171347,0.00006879224,0.00018851673,0.009182078],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99764967,0.0001638092,0.00049919484,0.00064000837,0.00037712028,0.00067020056],"domain_scores_gemma":[0.9984373,0.0001846818,0.00027365607,0.0005490538,0.00027236354,0.0002829783],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00076236855,0.00036461535,0.0005412066,0.00015656154,0.00018008093,0.000051577117,0.00016144903,0.00027578176,0.0006442454],"category_scores_gemma":[0.00010618964,0.00031255765,0.00030449787,0.00029194826,0.00006815283,0.00013870573,0.000056343226,0.00026281475,0.00047020023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0046474244,0.0006715257,0.00429978,0.001791955,0.0004962231,0.00018901352,0.00060267624,0.000020290685,0.90855336,0.0007251071,0.037065595,0.04093706],"study_design_scores_gemma":[0.010105777,0.0011723066,0.00428575,0.00025445488,0.00009402942,0.000028203021,0.00013160586,0.003170699,0.7351638,0.00088312966,0.24417189,0.0005383359],"about_ca_topic_score_codex":0.000045695197,"about_ca_topic_score_gemma":0.0000024136373,"teacher_disagreement_score":0.20710629,"about_ca_system_score_codex":0.0002067117,"about_ca_system_score_gemma":0.00031272444,"threshold_uncertainty_score":0.99993265},"labels":[],"label_agreement":null},{"id":"W2995692792","doi":"10.1016/j.celrep.2019.11.063","title":"LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; U.S. Department of Defense","keywords":"Autophagy; Cell biology; Hepatocyte growth factor; ATG8; Receptor tyrosine kinase; Biology; Signal transduction; Internalization; Cancer cell; Receptor; Cancer research; Cancer; Genetics; Apoptosis","score_opus":0.007408805941251326,"score_gpt":0.22963776287013926,"score_spread":0.22222895692888794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2995692792","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947185,0.0030372168,0.0000074130867,0.00021911274,0.0001298346,0.0006209267,0.0000017068301,0.000082699815,0.0011825935],"genre_scores_gemma":[0.99629307,0.00035526702,0.00007126261,0.00037715439,0.00004938523,0.00001181391,0.000068446374,0.000022079224,0.0027515353],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989782,0.00004834984,0.00027536054,0.00033575643,0.00019409705,0.00016820927],"domain_scores_gemma":[0.99918395,0.000117534786,0.00017368257,0.00031546748,0.000089288624,0.00012007596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025411305,0.00015091806,0.00023316612,0.000064026244,0.000090117275,0.000029758665,0.000027189955,0.00011272286,0.0001468645],"category_scores_gemma":[0.0000846959,0.00009820226,0.000043172782,0.00016458699,0.00006860175,0.00009065008,0.000030410221,0.00013167247,0.000017813714],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036756173,0.00023491154,0.18423541,0.00018558471,0.00020431537,0.0008956417,0.0016195789,0.000042093816,0.8055605,0.000054870838,0.0017149253,0.0048845885],"study_design_scores_gemma":[0.0015047387,0.00047987956,0.6298765,0.00009587082,0.0001968893,0.00069553195,0.00012214779,0.0032325133,0.35612628,0.0010777526,0.0063744546,0.0002174786],"about_ca_topic_score_codex":0.000065401124,"about_ca_topic_score_gemma":0.000005540658,"teacher_disagreement_score":0.44943425,"about_ca_system_score_codex":0.000024451558,"about_ca_system_score_gemma":0.00008659522,"threshold_uncertainty_score":0.4004572},"labels":[],"label_agreement":null},{"id":"W2995774252","doi":"10.1111/acel.13080","title":"Measuring biological aging in humans: A quest","year":2019,"lang":"en","type":"review","venue":"Aging Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":777,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"National Institute on Aging; National Institutes of Health","keywords":"Healthy aging; Gerontology; Disease; Successful aging; Psychological resilience; Psychological intervention; Population ageing; Mechanism (biology); Quality of life (healthcare); Population; Biology; Senescence; Psychology; Medicine; Environmental health; Genetics; Psychiatry","score_opus":0.17826560608760764,"score_gpt":0.37458736228778794,"score_spread":0.1963217562001803,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2995774252","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009113874,0.9902914,0.000009792561,0.00001819555,0.00024539125,0.0006437343,0.000004270933,0.00010354801,0.007772254],"genre_scores_gemma":[0.0027090027,0.995179,0.000066160785,0.00024109664,0.00034821397,0.00004413688,0.00008528565,0.00006186507,0.0012652382],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99834085,0.00013768094,0.00045983176,0.0005024256,0.00018103574,0.00037815125],"domain_scores_gemma":[0.9990914,0.0001246539,0.00016802858,0.00049147074,0.000021429467,0.000103020066],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033251135,0.0003566713,0.0014430733,0.00025496693,0.00003752015,0.000023150227,0.00020606938,0.0002519442,0.00015138052],"category_scores_gemma":[0.000024730323,0.00026239792,0.00041633524,0.00021911012,0.00003750809,0.00003821954,0.000072485804,0.000616791,0.00058928394],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012399902,0.0003738829,0.0016245928,0.0458154,0.00022349213,0.0011164234,0.00033765953,0.0000011476169,0.000029001501,0.0001469981,0.00030295286,0.950016],"study_design_scores_gemma":[0.00053958764,0.00005048511,0.00017252714,0.027163383,0.00037915588,0.00002388457,0.000018576908,0.000003151894,0.000023867851,0.000042790893,0.97126085,0.00032174357],"about_ca_topic_score_codex":0.000036607194,"about_ca_topic_score_gemma":0.0000019731478,"teacher_disagreement_score":0.9709579,"about_ca_system_score_codex":0.00015851052,"about_ca_system_score_gemma":0.00020921587,"threshold_uncertainty_score":0.99998283},"labels":[],"label_agreement":null},{"id":"W2996589204","doi":"10.1042/bcj20190596","title":"A lysosome independent role for TFEB in activating DNA repair and inhibiting apoptosis in breast cancer cells","year":2019,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"TFEB; Autophagy; Biology; Cancer research; Lysosome; Cell biology; Programmed cell death; DNA damage; Apoptosis; DNA; Biochemistry","score_opus":0.007643768811457551,"score_gpt":0.2640127471541178,"score_spread":0.25636897834266026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2996589204","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981324,0.0007982832,0.0000054486036,0.0006312476,0.000067676345,0.00025333656,0.000011547337,0.000016074191,0.00008397333],"genre_scores_gemma":[0.998765,0.00015043853,0.0002940975,0.00042997193,0.00028623387,0.000020478297,0.000003026086,0.000018403709,0.000032339623],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902123,0.000021852753,0.00030540908,0.00020144413,0.00017932475,0.00027076082],"domain_scores_gemma":[0.99955106,0.00006143037,0.000106491796,0.00008207911,0.000043699478,0.00015522876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022524215,0.00011609693,0.00024378148,0.00011997399,0.00002941075,0.00002011084,0.000050881314,0.00011584586,0.00009819388],"category_scores_gemma":[0.00002778097,0.00009874226,0.00009606047,0.00012236778,0.000021540369,0.00008433722,0.00003389748,0.00033750528,0.0000024394888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043457493,0.00012775435,0.073484205,0.000069259106,0.000035267483,0.000011337157,0.0002116375,0.0000030016508,0.9227279,0.0000074245827,0.00011830834,0.00276935],"study_design_scores_gemma":[0.0042408304,0.000069589405,0.063689314,0.00079835474,0.000021233725,0.00014539057,0.00052471756,0.00058893824,0.92947125,0.00024643334,0.00005555743,0.00014838293],"about_ca_topic_score_codex":0.000035696514,"about_ca_topic_score_gemma":0.0000014436393,"teacher_disagreement_score":0.009794896,"about_ca_system_score_codex":0.00016264271,"about_ca_system_score_gemma":0.000110169916,"threshold_uncertainty_score":0.40265927},"labels":[],"label_agreement":null},{"id":"W2999603405","doi":"10.3390/ijms21020578","title":"Pexophagy: A Model for Selective Autophagy","year":2020,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":132,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Autophagy; Peroxisome; Organelle; Cell biology; Cytosol; Biology; Vacuole; Intracellular; Biochemistry; Enzyme; Gene; Cytoplasm","score_opus":0.062319365693089004,"score_gpt":0.417293203028546,"score_spread":0.354973837335457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2999603405","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006326339,0.9783747,0.019738114,0.00036331208,0.0005576262,0.00036576026,0.000040714203,0.000012953665,0.0004835316],"genre_scores_gemma":[0.0018411136,0.9898446,0.006817153,0.0007761321,0.00053391553,0.000022805372,0.000011021349,0.000028485023,0.0001247797],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978994,0.00005298102,0.00065581134,0.0002639197,0.00095180026,0.00017606247],"domain_scores_gemma":[0.99820846,0.000108436536,0.00078442815,0.00009343506,0.00062108086,0.00018413062],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036145982,0.00023531905,0.0009742974,0.00038403113,0.000053830783,0.000076705284,0.00079677673,0.00011864098,0.000021829848],"category_scores_gemma":[0.0002269661,0.00016570109,0.0011075352,0.00026180173,0.00014679026,0.00013165362,0.0000551494,0.00028483183,0.000009599109],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013789022,0.00017833826,7.080865e-7,0.000705233,0.0019205937,0.0012395408,0.00018618893,0.00015488465,0.00009996942,0.0025330202,0.0011518081,0.9916918],"study_design_scores_gemma":[0.0018028974,0.0012966226,0.0000029694409,0.0072594113,0.002230888,0.003180364,0.000036158293,0.013882093,0.0013425768,0.006516051,0.96203643,0.0004135374],"about_ca_topic_score_codex":8.411204e-7,"about_ca_topic_score_gemma":1.2308325e-7,"teacher_disagreement_score":0.9912783,"about_ca_system_score_codex":0.00016461113,"about_ca_system_score_gemma":0.0027249954,"threshold_uncertainty_score":0.6757094},"labels":[],"label_agreement":null},{"id":"W3001120918","doi":"10.1016/j.jmb.2020.01.015","title":"Autophagy and Protein Secretion","year":2020,"lang":"en","type":"review","venue":"Journal of Molecular Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Associazione Italiana per la Ricerca sul Cancro; Ministry of Health, British Columbia; Ministero della Salute; Fondazione Cariplo","keywords":"Autophagy; Secretion; Secretory protein; Cell biology; Chemistry; Biology; Biochemistry; Apoptosis","score_opus":0.02235956845474795,"score_gpt":0.36395812596464633,"score_spread":0.34159855750989837,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3001120918","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007030048,0.9974324,0.0010133451,0.00019487456,0.000111633555,0.00038000432,0.000007091299,0.000009140751,0.00014851565],"genre_scores_gemma":[0.00025277009,0.9982886,0.0007221433,0.00030269896,0.00032176956,0.000008443321,0.000024268817,0.00002908512,0.000050240335],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998868,0.00021146017,0.00053183694,0.00015888202,0.00010133369,0.00012850988],"domain_scores_gemma":[0.99900055,0.000024100604,0.0005788326,0.00013154557,0.00007446178,0.00019052051],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015995129,0.00020616851,0.0014176122,0.00015184686,0.000016879694,0.0000072377634,0.000098872595,0.0003266124,0.0000650846],"category_scores_gemma":[0.00010618902,0.00013708323,0.00047603133,0.00010721584,0.000070235175,0.000015899466,0.000034685945,0.00046818543,0.000012723872],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006649766,0.000045550136,9.991279e-7,0.0031121273,0.00075270986,0.0020111294,0.0000128733955,1.8269603e-8,0.002950377,0.00087343634,0.0000851245,0.9900892],"study_design_scores_gemma":[0.0005441819,0.0010180204,0.0000043785367,0.0035378146,0.0010642176,0.0025821829,0.0000024063247,0.000001277726,0.0004407167,0.00075973786,0.98993564,0.000109409186],"about_ca_topic_score_codex":5.7561954e-7,"about_ca_topic_score_gemma":2.4147795e-8,"teacher_disagreement_score":0.98997974,"about_ca_system_score_codex":0.000041291587,"about_ca_system_score_gemma":0.00041740632,"threshold_uncertainty_score":0.5590092},"labels":[],"label_agreement":null},{"id":"W3002448802","doi":"10.1080/15548627.2020.1712812","title":"Loss of HSPA9 induces peroxisomal degradation by increasing pexophagy","year":2020,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Research Foundation of Korea; National Research Foundation","keywords":"Peroxisome; Biology; Cell biology; Autophagy; Gene knockdown; Biochemistry; Gene; Apoptosis","score_opus":0.020895598872458496,"score_gpt":0.2724723563480214,"score_spread":0.2515767574755629,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3002448802","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940353,0.0024868466,0.000312305,0.0012357901,0.00009111835,0.00024112646,0.000032178585,0.00013154683,0.0014338018],"genre_scores_gemma":[0.9965007,0.00011744213,0.00053891464,0.0022342876,0.00022005088,0.000011183574,0.000089908295,0.00003569833,0.0002518156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99866927,0.00008223815,0.00035682088,0.00030696997,0.000339485,0.00024520795],"domain_scores_gemma":[0.9991768,0.00007956054,0.0001556599,0.0002350969,0.000087282766,0.00026559716],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012400509,0.00018809448,0.0003831562,0.000060990646,0.00006536915,0.000014893908,0.00014074461,0.00012378277,0.0006226884],"category_scores_gemma":[0.00015376577,0.00017223113,0.00013425574,0.0002768499,0.00010999998,0.00016552288,0.00004253656,0.00017364044,0.00007651316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011524216,0.0005667443,0.0096604675,0.00027708785,0.00033598737,0.00022604551,0.0015192255,0.0000063181933,0.95863116,0.0016932841,0.0042520342,0.021679202],"study_design_scores_gemma":[0.0026085344,0.0006464301,0.06253469,0.00006990557,0.0001627771,0.00006675103,0.00020117388,0.00052007305,0.92934895,0.00021279788,0.003398622,0.00022930923],"about_ca_topic_score_codex":0.00009028167,"about_ca_topic_score_gemma":5.965401e-7,"teacher_disagreement_score":0.052874226,"about_ca_system_score_codex":0.00003330788,"about_ca_system_score_gemma":0.00013677565,"threshold_uncertainty_score":0.70233816},"labels":[],"label_agreement":null},{"id":"W3003103630","doi":"10.1016/j.celrep.2019.12.050","title":"Human Liver Memory CD8+ T Cells Use Autophagy for Tissue Residence","year":2020,"lang":"en","type":"article","venue":"Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute for Health and Care Research; Kennedy Trust for Rheumatology Research; Cancer Research UK; Wellcome Trust; Medical Research Foundation; Merck KGaA","keywords":"Autophagy; Cell biology; CD8; Biology; Hepatic stellate cell; Cytotoxic T cell; Cytokine; Immune system; Ex vivo; Immunology; Cancer research; Apoptosis; In vitro; Biochemistry; Endocrinology","score_opus":0.038907676748083174,"score_gpt":0.29589443217046874,"score_spread":0.2569867554223856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3003103630","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902309,0.0019669067,0.00052902626,0.00036105386,0.00037143394,0.0010962647,0.000008179425,0.00023081034,0.0052053886],"genre_scores_gemma":[0.97175395,0.00007263854,0.0010481089,0.0029502297,0.0005026917,0.0000442761,0.000034188397,0.000050200986,0.023543727],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985787,0.000023245993,0.00040131016,0.00046962436,0.0002568035,0.0002703044],"domain_scores_gemma":[0.99875927,0.00005591521,0.00020451532,0.000509476,0.00010491006,0.00036592837],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012521604,0.00017934176,0.00031040137,0.00003970056,0.00011052685,0.000031527452,0.00007611298,0.0001113669,0.00089599966],"category_scores_gemma":[0.000091303154,0.00016589176,0.00014442648,0.000100909594,0.00006279226,0.00012699197,0.000040709972,0.0001328336,0.00009063053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013307814,0.0002165921,0.00048828503,0.0004374524,0.000057834513,0.016542595,0.0009335003,0.000026813956,0.8898715,0.00005959933,0.08941699,0.0018157951],"study_design_scores_gemma":[0.00063305977,0.0003678988,0.0040372093,0.00005306571,0.00014506571,0.00012242484,0.00003977415,0.00009693248,0.93045247,0.00020631992,0.0636552,0.00019058354],"about_ca_topic_score_codex":0.00003934811,"about_ca_topic_score_gemma":0.0000013206436,"teacher_disagreement_score":0.040581,"about_ca_system_score_codex":0.000031779822,"about_ca_system_score_gemma":0.00013554124,"threshold_uncertainty_score":0.9810568},"labels":[],"label_agreement":null},{"id":"W3003816116","doi":"10.1038/s41418-020-0496-1","title":"NF-κB-p62-NRF2 survival signaling is associated with high ROR1 expression in chronic lymphocytic leukemia","year":2020,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Associazione Italiana per la Ricerca sul Cancro; Ministerio de Ciencia e Innovación; National Institute of Allergy and Infectious Diseases; European Commission; National Institute of Environmental Health Sciences; Instituto de Salud Carlos III; Cancer Research Society; Leukemia and Lymphoma Society","keywords":"Chronic lymphocytic leukemia; Venetoclax; B-cell activating factor; Cancer research; Autophagy; Signal transduction; NF-κB; Leukemia; Chemistry; Biology; Cell biology; Apoptosis; Immunology; B cell; Antibody; Biochemistry","score_opus":0.01661923606356103,"score_gpt":0.2312569632657009,"score_spread":0.21463772720213986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3003816116","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99728143,0.001038685,0.0009221428,0.00005964226,0.000057244448,0.00024794944,0.000009996235,0.00006894409,0.0003139868],"genre_scores_gemma":[0.99867314,0.00018381854,0.000036988058,0.00051313563,0.00013288744,0.000014567433,0.000258438,0.000023872915,0.00016314245],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900144,0.000055019857,0.00020190222,0.00028829896,0.00023518209,0.0002181288],"domain_scores_gemma":[0.99949604,0.000052231455,0.00010418697,0.0001163005,0.000039881685,0.00019134542],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000549716,0.00016918965,0.00027874124,0.000058189045,0.00007009351,0.000030104708,0.00004670924,0.00011537013,0.00022715295],"category_scores_gemma":[0.000023306795,0.00013307192,0.000045286874,0.00014080288,0.000018074064,0.00009085967,0.000021209948,0.00012289116,0.000012404725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023528414,0.0002637595,0.15090598,0.00071135315,0.00027937203,0.00021896338,0.0036759353,0.0011957923,0.8374886,0.00018236453,0.00036422902,0.0023608],"study_design_scores_gemma":[0.013948593,0.00069910084,0.38104546,0.00048514688,0.00030205512,0.0000023028088,0.00012713252,0.04398087,0.5587197,0.0002880812,0.00005356243,0.00034800242],"about_ca_topic_score_codex":0.0000671471,"about_ca_topic_score_gemma":0.00000795824,"teacher_disagreement_score":0.27876893,"about_ca_system_score_codex":0.00085279834,"about_ca_system_score_gemma":0.00043386707,"threshold_uncertainty_score":0.54265153},"labels":[],"label_agreement":null},{"id":"W3004473469","doi":"10.1016/j.bpj.2019.11.2536","title":"A Snake Uncoiled: Activation of Parkin, a Ubiquitin Ligase Involved in Parkinson'S Disease","year":2020,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Parkin; Mitophagy; PINK1; Ubiquitin ligase; Ubiquitin; Chemistry; Cell biology; Mitochondrion; Ubiquitin-Protein Ligases; Parkinson's disease; Cytosol; Biochemistry; Autophagy; Biophysics; Biology; Enzyme; Disease; Medicine","score_opus":0.02505013876894483,"score_gpt":0.27449239952275,"score_spread":0.24944226075380518,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3004473469","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945904,0.00008897679,0.00017128311,0.0047912356,0.00004937288,0.00017375126,0.000012239213,0.00002374012,0.000098978206],"genre_scores_gemma":[0.99639606,0.00009753496,0.00011429283,0.0025427316,0.00079290883,0.000009897759,0.000014081365,0.000018920551,0.000013584535],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988561,0.00007058212,0.00033414434,0.00018145179,0.00035281215,0.00020487528],"domain_scores_gemma":[0.99897003,0.000049784197,0.00016644306,0.00013317562,0.000082167215,0.00059837947],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000082608945,0.00014022794,0.0003183565,0.00007362799,0.000037711154,0.000017391718,0.00010087739,0.000052320353,0.00009551668],"category_scores_gemma":[0.00014843707,0.00011315637,0.00020278618,0.00031046188,0.00007073158,0.00011791727,0.000026820519,0.00031875313,0.000027104554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0076599154,0.0020376237,0.035368346,0.00024705395,0.00022027435,0.0012261574,0.00095096434,0.000050326536,0.93835723,0.00051124644,0.002039428,0.011331448],"study_design_scores_gemma":[0.009232269,0.0013724499,0.42415652,0.00079665583,0.00027651782,0.0000199904,0.00039928514,0.0043420577,0.54046637,0.0014761296,0.017054709,0.00040704443],"about_ca_topic_score_codex":0.0000066058424,"about_ca_topic_score_gemma":5.387673e-7,"teacher_disagreement_score":0.39789084,"about_ca_system_score_codex":0.00004952885,"about_ca_system_score_gemma":0.00023470013,"threshold_uncertainty_score":0.4614383},"labels":[],"label_agreement":null},{"id":"W3006436854","doi":"10.1139/cjpp-2019-0477","title":"Inhibition of autophagy improves resistance and enhances sensitivity of gastric cancer cells to cisplatin","year":2020,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Science and Technology Major Project","keywords":"Autophagy; Cisplatin; Apoptosis; Cancer cell; Cancer research; mTORC1; Cancer; PI3K/AKT/mTOR pathway; Chemistry; Protein kinase B; Pharmacology; Biology; Medicine; Chemotherapy; Internal medicine; Biochemistry","score_opus":0.012439902907596147,"score_gpt":0.2805759309204335,"score_spread":0.2681360280128373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3006436854","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954665,0.0027182258,0.00004143284,0.0013949359,0.00017706434,0.000107531734,0.00005507015,0.0000016316983,0.000037608697],"genre_scores_gemma":[0.99681836,0.00043669617,0.00012935098,0.0023831837,0.00020422215,0.0000019939914,0.0000015980486,0.00000531817,0.000019249086],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99935,0.00011373823,0.00024387012,0.00010894232,0.000041141884,0.00014229148],"domain_scores_gemma":[0.9991153,0.00009967701,0.00021222202,0.00003418184,0.00012479488,0.00041381756],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119211814,0.00008085132,0.000358524,0.00010347985,0.00003567215,0.000001225873,0.000027544413,0.00006514894,0.00028719637],"category_scores_gemma":[0.000023682505,0.000071318565,0.000041999243,0.00011563969,0.00021769648,0.000041394072,0.0000080559685,0.00014448237,5.327013e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006586394,0.000017587949,0.00033197328,0.00021704263,0.00012152979,0.000090584355,0.00066056254,0.000019260327,0.9955359,0.00003316972,0.0012165438,0.0010971931],"study_design_scores_gemma":[0.00097040535,0.0005880007,0.029100176,0.00004892345,0.00013182698,0.000022001095,0.00005405082,0.00005314912,0.9683874,0.00018446872,0.00040888682,0.00005068283],"about_ca_topic_score_codex":0.00023613116,"about_ca_topic_score_gemma":0.00035221298,"teacher_disagreement_score":0.028768202,"about_ca_system_score_codex":0.000016548614,"about_ca_system_score_gemma":0.0004449158,"threshold_uncertainty_score":0.31445986},"labels":[],"label_agreement":null},{"id":"W3006441058","doi":"10.1080/15548627.2020.1728099","title":"LC3C mediates selective autophagy of the MET RTK, inhibiting cancer cell invasion","year":2020,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Cell biology; Receptor tyrosine kinase; BAG3; Signal transduction; Cancer cell; Cell; Cancer; Cancer research; Biochemistry; Apoptosis; Genetics","score_opus":0.020982707127475016,"score_gpt":0.2695786176124028,"score_spread":0.2485959104849278,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3006441058","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9854925,0.007073146,0.00003713957,0.0014772117,0.00028741243,0.0005736024,0.000041827847,0.00014849818,0.004868606],"genre_scores_gemma":[0.99303466,0.00046667573,0.00022042869,0.0052462122,0.0004273882,0.000056372446,0.000014843038,0.00005192746,0.00048147008],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981977,0.00011816815,0.00044493238,0.0004091162,0.00046992552,0.0003602041],"domain_scores_gemma":[0.9988306,0.00014719156,0.00028074108,0.0003298483,0.00016375464,0.00024785948],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014791725,0.00026071264,0.0004929062,0.000041772342,0.00013145857,0.000013487859,0.00025932008,0.0001487351,0.0010126932],"category_scores_gemma":[0.00017576007,0.00018119127,0.00026991245,0.00051431666,0.00013607054,0.00014134734,0.00014272031,0.0003188369,0.000049442766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044224932,0.00044969658,0.00810731,0.00050253305,0.0004072115,0.00010181358,0.006562989,0.000111850655,0.9638283,0.0011003866,0.005302434,0.013083207],"study_design_scores_gemma":[0.0019307315,0.00032327237,0.028754486,0.00012377118,0.00021157588,0.000008678161,0.00028656243,0.00075053517,0.9654048,0.0003549357,0.0016739174,0.00017674034],"about_ca_topic_score_codex":0.0002917929,"about_ca_topic_score_gemma":0.000019438921,"teacher_disagreement_score":0.020647176,"about_ca_system_score_codex":0.00010724844,"about_ca_system_score_gemma":0.00043334044,"threshold_uncertainty_score":0.9999005},"labels":[],"label_agreement":null},{"id":"W3007125199","doi":"10.1039/c9nr10131d","title":"Autophagic stress; a new cellular response to nanoparticles. Could it be a new strategy for inhibition of liver cancer cell invasion and metastasis?","year":2020,"lang":"en","type":"article","venue":"Nanoscale","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Associated Medical Services","funders":"Faculty of Science, Chiang Mai University; National Research Council of Thailand","keywords":"Autophagy; Metastasis; Cancer cell; Cancer; Liver cancer; Cancer research; Cell; Cancer metastasis; Stress (linguistics); Cell biology; Materials science; Nanotechnology; Chemistry; Medicine; Biology; Apoptosis; Biochemistry; Internal medicine","score_opus":0.06158644813394486,"score_gpt":0.3078849104116874,"score_spread":0.24629846227774255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3007125199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98416275,0.0060380157,0.00059306243,0.00805091,0.000044275654,0.00084780005,0.00014954784,0.00004219196,0.00007145121],"genre_scores_gemma":[0.99245423,0.00034289458,0.00074974826,0.004538569,0.00014618291,0.000035270852,0.000024726558,0.000029105311,0.0016792589],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988755,0.000056644567,0.00027905655,0.00031990052,0.00024443987,0.00022448204],"domain_scores_gemma":[0.99899256,0.0000742712,0.00009153395,0.00018251166,0.0000745668,0.000584534],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011266549,0.00016437512,0.00032346894,0.000044196026,0.000046992838,0.000017185299,0.000059942355,0.00010221396,0.0006050018],"category_scores_gemma":[0.0000611939,0.00014680305,0.00009908943,0.00019290428,0.000037810823,0.000107402426,0.00003884697,0.00008145759,0.000011146134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0048819454,0.00016938022,0.00012578352,0.00020447191,0.000049982624,0.000043116703,0.0020322762,0.000034725992,0.96711636,0.00004083494,0.020815933,0.0044851834],"study_design_scores_gemma":[0.0040190523,0.0014825095,0.0016158198,0.00013396083,0.00020461075,0.0000019900244,0.0003191263,0.00038421046,0.9797831,0.00010266733,0.011812284,0.00014063145],"about_ca_topic_score_codex":0.00052201183,"about_ca_topic_score_gemma":0.00009263744,"teacher_disagreement_score":0.012666772,"about_ca_system_score_codex":0.000046260815,"about_ca_system_score_gemma":0.00046732265,"threshold_uncertainty_score":0.6624346},"labels":[],"label_agreement":null},{"id":"W3008311995","doi":"10.1111/tra.12723","title":"Ultrastructural insights into pathogen clearance by autophagy","year":2020,"lang":"en","type":"article","venue":"Traffic","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Directorate for Biological Sciences; Wellcome Trust; Astellas Pharma; Astellas Foundation for Research on Metabolic Disorders; Medical Research Council Canada","keywords":"Biology; Vacuole; Autophagy; Cell biology; Cytosol; Mitophagy; Ubiquitin; Endoplasmic reticulum; Bacterial outer membrane; Salmonella; Bacteria; Biochemistry; Apoptosis; Cytoplasm; Escherichia coli; Genetics","score_opus":0.009097372369761861,"score_gpt":0.24142955440791403,"score_spread":0.23233218203815217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3008311995","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993593,0.0040534213,0.00007125644,0.0012552765,0.00009836195,0.00020512583,0.000007988502,0.00027111376,0.00044445327],"genre_scores_gemma":[0.9946708,0.0001287937,0.00020941881,0.0044464986,0.0002674998,0.000008593635,0.00005891606,0.000028297443,0.00018118598],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.999151,0.000026167321,0.00017281607,0.00026613762,0.00019271167,0.00019114756],"domain_scores_gemma":[0.9994583,0.000016127839,0.000038886406,0.0001697056,0.00002616503,0.0002908259],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000018285094,0.00015042422,0.00023161704,0.000021866414,0.00006463575,0.000013103877,0.00010690095,0.00007348492,0.000424879],"category_scores_gemma":[0.000018244898,0.00012290149,0.00009679795,0.00016844504,0.00006685117,0.00006811831,0.000010679012,0.00016217795,0.00030235073],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020888874,0.0004286427,0.0006710278,0.0003793194,0.0004153639,0.0007573268,0.02174653,0.0004858706,0.7216177,0.00073761994,0.032294136,0.21837759],"study_design_scores_gemma":[0.020617377,0.0042333887,0.20616142,0.00026126183,0.0006284659,0.0001987726,0.0013459482,0.027482474,0.33935687,0.0009959266,0.39667755,0.0020405254],"about_ca_topic_score_codex":0.0000030687997,"about_ca_topic_score_gemma":6.489631e-7,"teacher_disagreement_score":0.3822608,"about_ca_system_score_codex":0.000022629603,"about_ca_system_score_gemma":0.00005525997,"threshold_uncertainty_score":0.5011777},"labels":[],"label_agreement":null},{"id":"W3008777148","doi":"10.1007/s10557-019-06927-4","title":"Hydrogen Sulfide Switch Phenomenon Regulating Autophagy in Cardiovascular Diseases","year":2020,"lang":"en","type":"review","venue":"Cardiovascular Drugs and Therapy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Natural Science Foundation of China","keywords":"Autophagy; Medicine; Cell biology; Mechanism (biology); Intracellular; Vasodilation; Disease; Programmed cell death; Neuroscience; Biology; Internal medicine; Biochemistry; Apoptosis","score_opus":0.02377304949383676,"score_gpt":0.27898146413672664,"score_spread":0.2552084146428899,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3008777148","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013989265,0.99461883,0.00004803277,0.000033455966,0.0002144184,0.0026789913,0.00007652416,0.00022920565,0.00070163014],"genre_scores_gemma":[0.0020803895,0.9950661,0.00007334056,0.00022394059,0.0013434478,0.00047892096,0.00031115164,0.00031334435,0.0001093448],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99475914,0.00065695506,0.0010592293,0.0016266106,0.0011155489,0.0007825215],"domain_scores_gemma":[0.99680614,0.00013048356,0.00023241666,0.0020798421,0.000089322086,0.0006617769],"candidate_categories":["metaepi_narrow","metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.00082104735,0.0011760277,0.0073982985,0.00040565498,0.00017987289,0.000097496326,0.00037126624,0.00054457143,0.00007758942],"category_scores_gemma":[0.000053266565,0.00095657515,0.010829053,0.00092717895,0.00017745886,0.00014464141,0.00015150657,0.0007515452,0.000054155975],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000075901,0.0001239538,0.000019759253,0.004894712,0.027555974,0.00096615567,0.00029870053,0.000023797098,0.0000015381893,0.00009100029,0.000027357783,0.96592116],"study_design_scores_gemma":[0.0039017643,0.0001364481,0.00008934931,0.004299205,0.0085589,0.0002831688,0.00007559653,0.00003950792,0.00002340259,0.00020729657,0.9814904,0.000894986],"about_ca_topic_score_codex":0.00007343655,"about_ca_topic_score_gemma":2.7650242e-7,"teacher_disagreement_score":0.981463,"about_ca_system_score_codex":0.000250768,"about_ca_system_score_gemma":0.00060700375,"threshold_uncertainty_score":0.9992885},"labels":[],"label_agreement":null},{"id":"W3009732833","doi":"10.3389/fcell.2020.00138","title":"Autophagy and Stem Cells: Self-Eating for Self-Renewal","year":2020,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":176,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Autophagy; Stem cell; Cell biology; Biology; Neurodegeneration; Cellular differentiation; Cancer stem cell; Neuroscience; Disease; Medicine; Biochemistry; Pathology; Apoptosis","score_opus":0.020072041929541064,"score_gpt":0.2787861468084647,"score_spread":0.25871410487892366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3009732833","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011619206,0.99575096,0.0001587842,0.000013897315,0.0006804893,0.0012419374,0.000069620044,0.00010094378,0.00082143967],"genre_scores_gemma":[0.0001246922,0.95316935,0.045578312,0.00023565147,0.00014462853,0.000189144,0.00018338219,0.000047460115,0.00032739542],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982728,0.000088236375,0.00055375876,0.00064533565,0.00006710322,0.00037276576],"domain_scores_gemma":[0.9993613,0.00012250636,0.00017839977,0.000103659084,0.00001623415,0.0002179363],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014037747,0.00044077216,0.0016352418,0.00018616955,0.00009539545,0.00001727108,0.00011083229,0.0004726943,0.000014734901],"category_scores_gemma":[0.0000059860736,0.00035284073,0.00015556092,0.00015481397,0.00007896105,0.000029309122,0.00011576399,0.00025773203,0.000010055382],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007199672,0.00012705204,0.00077935256,0.012547846,0.0005371892,0.000082554645,0.0006351752,1.0777732e-8,0.000032948497,0.000031170304,0.0028116275,0.9823431],"study_design_scores_gemma":[0.0015292015,0.00027790785,0.000016183758,0.0010575275,0.00044637854,0.00007778981,0.00027091344,0.000028851236,0.00036631248,0.00016906529,0.9953667,0.00039316333],"about_ca_topic_score_codex":0.000003912718,"about_ca_topic_score_gemma":6.034281e-7,"teacher_disagreement_score":0.9925551,"about_ca_system_score_codex":0.00018445554,"about_ca_system_score_gemma":0.00048244957,"threshold_uncertainty_score":0.99989235},"labels":[],"label_agreement":null},{"id":"W3011664692","doi":"10.1007/s00432-020-03174-1","title":"Role of the autophagy-related marker LC3 expression in hepatocellular carcinoma: a meta-analysis","year":2020,"lang":"en","type":"review","venue":"Journal of Cancer Research and Clinical Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Shanghai Municipal Health Bureau; National Natural Science Foundation of China","keywords":"Hepatocellular carcinoma; Meta-analysis; Medicine; Internal medicine; Hazard ratio; Oncology; Cochrane Library; Cirrhosis; Stage (stratigraphy); Confidence interval; Biology","score_opus":0.2801490935420373,"score_gpt":0.5478840458248665,"score_spread":0.2677349522828292,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3011664692","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011655528,0.98589426,0.0000012655037,0.0012751586,0.00012503593,0.0006868102,0.000027866176,0.000002764464,0.00033129635],"genre_scores_gemma":[0.029541112,0.96951336,0.000045313926,0.00014043278,0.00026259304,0.000053522068,0.0000042065926,0.000026833734,0.00041260783],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9922906,0.0032191987,0.0028184138,0.00036804748,0.0009486503,0.00035506542],"domain_scores_gemma":[0.99464333,0.0022469703,0.0016818484,0.0004380526,0.00048547718,0.000504301],"candidate_categories":["research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004614422,0.00025895966,0.006639983,0.000511121,0.000056721496,0.000011917621,0.0005080853,0.00072361296,0.0012389078],"category_scores_gemma":[0.0007673371,0.00012591273,0.0047103856,0.0014654844,0.000543081,0.000049962866,0.0002441969,0.0032810115,0.000004785746],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029172099,0.0023287346,0.015226056,0.0032421635,0.2159101,0.0023142372,0.00017896315,0.0000018973445,0.00006296618,0.00007938553,0.001440647,0.75629765],"study_design_scores_gemma":[0.002229422,0.0023406115,0.005755652,0.0010387261,0.16736023,0.00007631912,0.000058430218,0.0000689934,0.000045075914,0.00062327494,0.8202776,0.00012569512],"about_ca_topic_score_codex":0.00008667065,"about_ca_topic_score_gemma":0.000040753734,"teacher_disagreement_score":0.8188369,"about_ca_system_score_codex":0.00027142698,"about_ca_system_score_gemma":0.0045313016,"threshold_uncertainty_score":0.9996741},"labels":[],"label_agreement":null},{"id":"W3012116707","doi":"10.1007/s00294-020-01062-2","title":"N-degron-mediated degradation and regulation of mitochondrial PINK1 kinase","year":2020,"lang":"en","type":"review","venue":"Current Genetics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"PINK1; Parkin; Mitophagy; Biology; Mitochondrion; Cell biology; Ubiquitin ligase; Degron; Autophagy; Ubiquitin; Genetics; Parkinson's disease; Gene; Medicine; Apoptosis; Internal medicine; Disease","score_opus":0.06342400532519474,"score_gpt":0.3593242464296933,"score_spread":0.29590024110449853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012116707","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00048067872,0.9974897,0.00022545466,0.000015560478,0.0007206111,0.0008982542,0.000106900814,0.000030967974,0.00003190248],"genre_scores_gemma":[0.000044345594,0.9969768,0.000578983,0.000011389817,0.00054466975,0.000030727104,0.0017273135,0.000040258736,0.00004550547],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987415,0.00007998577,0.0005111837,0.0002918081,0.00024735654,0.00012813856],"domain_scores_gemma":[0.9990576,0.0000761986,0.0003404856,0.00027637012,0.000077614146,0.00017175043],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000044089244,0.00025979962,0.00091547257,0.00011600047,0.000030541225,0.000010112764,0.00007723956,0.00018855347,0.000057147765],"category_scores_gemma":[0.00008772293,0.00021842307,0.00026986023,0.00021989271,0.00007028926,0.000019347857,0.000038813134,0.00024954288,0.000027109741],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025907948,0.000083556275,0.000013752624,0.009386132,0.00012685267,0.0000038365774,0.000023436227,1.8143793e-7,0.000061142746,0.00006551738,0.0005945285,0.98961514],"study_design_scores_gemma":[0.00071351655,0.00015386325,0.000120990735,0.0049914676,0.001924138,0.000009609785,0.0000030100516,0.00009396359,0.000080892176,0.00011693573,0.99161476,0.00017683033],"about_ca_topic_score_codex":7.0095905e-7,"about_ca_topic_score_gemma":2.9082753e-7,"teacher_disagreement_score":0.99102026,"about_ca_system_score_codex":0.00003790284,"about_ca_system_score_gemma":0.00036248632,"threshold_uncertainty_score":0.89070344},"labels":[],"label_agreement":null},{"id":"W3012718994","doi":"10.1155/2020/8475840","title":"The Prognostic Value of Autophagy‐Related Markers Bclin‐1 and LC‐3 in Colorectal Cancers: A Systematic Review and Meta‐analysis","year":2020,"lang":"en","type":"review","venue":"Evidence-based Complementary and Alternative Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Meta-analysis; Colorectal cancer; Hazard ratio; Medicine; Confidence interval; Oncology; Internal medicine; Autophagy; Cochrane Library; Subgroup analysis; Gastroenterology; Cancer; Apoptosis; Biology","score_opus":0.0978811205418449,"score_gpt":0.39479098806955804,"score_spread":0.29690986752771314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012718994","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00043420834,0.9898818,0.000024548277,0.0034042143,0.000058124035,0.0060230102,0.00013629573,0.00002089165,0.000016869215],"genre_scores_gemma":[0.007959066,0.9893474,0.000057429737,0.0015689835,0.00005713939,0.0007948885,0.00015210036,0.000031032076,0.000031979303],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99519897,0.0014054192,0.0018134638,0.0006915763,0.00058114476,0.00030942223],"domain_scores_gemma":[0.9938628,0.004244715,0.0011322706,0.00035980312,0.000111104375,0.00028929432],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0017696646,0.0006318695,0.0068259547,0.000354665,0.00013296687,0.000019463067,0.00027204846,0.00007448408,0.00034551456],"category_scores_gemma":[0.00067228056,0.0003347094,0.00059305463,0.001079309,0.0007399735,0.00010714661,0.00011597382,0.00046735234,0.0000013586446],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023239231,0.000075319695,0.00032489683,0.8311548,0.15813111,0.0003941963,0.00033929275,0.0000025358183,0.0000014500521,0.0003407675,0.00010230448,0.008900922],"study_design_scores_gemma":[0.001449838,0.0013318167,0.00030774696,0.29358375,0.6995105,0.00006140775,0.00018152865,0.00080218975,0.00000423992,0.00011951226,0.0023534857,0.00029398064],"about_ca_topic_score_codex":0.000604095,"about_ca_topic_score_gemma":0.000059698115,"teacher_disagreement_score":0.5413794,"about_ca_system_score_codex":0.00015488721,"about_ca_system_score_gemma":0.0003590906,"threshold_uncertainty_score":0.9999105},"labels":[],"label_agreement":null},{"id":"W3012996909","doi":"10.3390/cells9040805","title":"Autophagy Modulators Profoundly Alter the Astrocyte Cellular Proteome","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Children's Hospital Research Institute of Manitoba","keywords":"Autophagy; Cell biology; Biology; Proteome; BAG3; ATG8; ATG5; Sequestosome 1; TFEB; Biochemistry; Apoptosis","score_opus":0.016624624723870822,"score_gpt":0.23831809559700895,"score_spread":0.22169347087313812,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012996909","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905046,0.00076818175,0.00143828,0.0034685067,0.0002335188,0.0011564263,0.000007098062,0.00015907387,0.0022643027],"genre_scores_gemma":[0.99040675,0.000019920113,0.00031951218,0.0061272285,0.0006979608,0.000060768096,0.00001189473,0.000038093145,0.0023178565],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989239,0.000043442407,0.0002010991,0.00027897334,0.0002711276,0.00028143753],"domain_scores_gemma":[0.99925315,0.00001969548,0.00006487748,0.0003672272,0.000042540763,0.0002525294],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008455529,0.00017012807,0.00022198398,0.000023140848,0.00009624042,0.000028052646,0.00017504761,0.00006918303,0.00085102604],"category_scores_gemma":[0.000013964324,0.00010813395,0.00014945828,0.0001630369,0.00008707083,0.000059714468,0.00004622401,0.00022828366,0.0009698611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033184767,0.00016509448,0.00030675915,0.00016121133,0.0001993027,0.0002489262,0.0013251742,0.00007267636,0.9877575,0.00039525251,0.006668551,0.002367713],"study_design_scores_gemma":[0.0011166885,0.000295744,0.0017015998,0.000024107965,0.00008722467,0.000006437378,0.00006611863,0.00220931,0.94801694,0.00019179047,0.04614421,0.0001398031],"about_ca_topic_score_codex":0.000004755197,"about_ca_topic_score_gemma":1.1231183e-7,"teacher_disagreement_score":0.039740525,"about_ca_system_score_codex":0.000028952176,"about_ca_system_score_gemma":0.00010011495,"threshold_uncertainty_score":0.999808},"labels":[],"label_agreement":null},{"id":"W3014137344","doi":"10.1080/15548627.2020.1752471","title":"Acetylation of STX17 (syntaxin 17) controls autophagosome maturation","year":2020,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":134,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Genetics","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Cell biology; Autophagosome; Biology; Acetylation; Autophagy; SAP30; Lysosome; Biochemistry; Histone methyltransferase","score_opus":0.022007785858285594,"score_gpt":0.2738649786335808,"score_spread":0.25185719277529517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3014137344","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9863362,0.0013193114,0.00198704,0.0040863175,0.00017683225,0.0006806984,0.00003586332,0.00021492445,0.005162854],"genre_scores_gemma":[0.9939662,0.000046160516,0.0007290138,0.0038050278,0.00036221172,0.000023982102,0.00009752037,0.000030890093,0.0009389972],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984673,0.00006892718,0.00053816044,0.00030768604,0.00039781415,0.00022006454],"domain_scores_gemma":[0.9989821,0.00007588662,0.00025401622,0.0003340349,0.00013344143,0.0002205308],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014163784,0.00019102411,0.00050361454,0.000071249306,0.00005281835,0.000017892078,0.00012360672,0.00013681057,0.0016416013],"category_scores_gemma":[0.00014807889,0.00016627045,0.00020561305,0.00025814204,0.00006821346,0.00018572182,0.000029030885,0.00016835135,0.00020909945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028306313,0.00044223026,0.0017772837,0.00028985526,0.0004933126,0.00017145117,0.0020142968,0.00017346685,0.95379055,0.010176188,0.0072013964,0.020639313],"study_design_scores_gemma":[0.009015388,0.0013612612,0.2687025,0.00010484002,0.00033173503,0.000044179422,0.00016859146,0.016047813,0.6845064,0.0016124357,0.01770108,0.00040374312],"about_ca_topic_score_codex":0.000010365121,"about_ca_topic_score_gemma":5.151238e-7,"teacher_disagreement_score":0.26928416,"about_ca_system_score_codex":0.000038040467,"about_ca_system_score_gemma":0.00012794042,"threshold_uncertainty_score":0.99927104},"labels":[],"label_agreement":null},{"id":"W3014471310","doi":"10.3389/fcell.2020.00208","title":"Disrupting the LC3 Interaction Region (LIR) Binding of Selective Autophagy Receptors Sensitizes AML Cell Lines to Cytarabine","year":2020,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Toronto; Deutsche Forschungsgemeinschaft; European Molecular Biology Laboratory","keywords":"Autophagy; Cell biology; Receptor; Biology; Plasma protein binding; Chemistry; Genetics","score_opus":0.01601028953637695,"score_gpt":0.2563704316905022,"score_spread":0.24036014215412527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3014471310","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99550205,0.0007225112,0.000973947,0.000759507,0.0005445829,0.00030838104,0.000005679579,0.000028695997,0.0011546637],"genre_scores_gemma":[0.9922237,0.0005552483,0.0057718246,0.0010959582,0.000107791224,0.000013821007,0.000046251113,0.000013398787,0.00017201649],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990763,0.00007420638,0.00028339715,0.00028530593,0.00006250707,0.00021826345],"domain_scores_gemma":[0.99963117,0.00006814284,0.00009985882,0.00006129378,0.000033746895,0.00010581641],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000100422105,0.00015115617,0.00030237468,0.00011721046,0.00008161744,0.0000063870893,0.00006237381,0.00009709909,0.000019845682],"category_scores_gemma":[0.00004516944,0.00010837081,0.000046444573,0.0002841062,0.000087613786,0.000045258523,0.00006872001,0.00017306948,0.0000105508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0039878804,0.00029281047,0.2790397,0.00035842805,0.00021947808,0.00011087017,0.021949764,0.00003510958,0.6187899,0.00003460039,0.019516004,0.05566544],"study_design_scores_gemma":[0.0019601923,0.00072112697,0.01534296,0.000116905234,0.000048610946,0.000041860258,0.011289756,0.0005521533,0.9626128,0.000097587756,0.00694614,0.00026988066],"about_ca_topic_score_codex":0.000023481103,"about_ca_topic_score_gemma":0.0000028318213,"teacher_disagreement_score":0.3438229,"about_ca_system_score_codex":0.00007930637,"about_ca_system_score_gemma":0.000060649323,"threshold_uncertainty_score":0.44192335},"labels":[],"label_agreement":null},{"id":"W3014943606","doi":"10.1101/2020.04.02.022228","title":"The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration <i>in vivo</i>","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; AMPK; Cell migration; Biology; Bioenergetics; Cell; Chemistry; Mitochondrion; Biochemistry; Phosphorylation; Protein kinase A","score_opus":0.013477291853835748,"score_gpt":0.2657220779500371,"score_spread":0.2522447860962014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3014943606","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99069804,0.0025215147,0.00065395393,0.0039490657,0.0004816011,0.001096365,0.00032207268,0.0002652022,0.0000121775975],"genre_scores_gemma":[0.9972729,0.0005426433,0.00036177778,0.0010731894,0.00044729642,0.00014587419,0.0000012679903,0.00012925167,0.000025787891],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9972132,0.00019444677,0.0006578161,0.0009471293,0.00043150975,0.00055590185],"domain_scores_gemma":[0.99799865,0.00021209479,0.00031490982,0.00088777905,0.00019815592,0.0003884179],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00046612628,0.00056071463,0.0006980327,0.00018884613,0.0001902287,0.00019682139,0.00038842516,0.00043139575,0.0000414267],"category_scores_gemma":[0.00022086254,0.0004807538,0.00017834092,0.00036841945,0.00021358453,0.000115783005,0.00038714425,0.001092796,0.00002277686],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009276526,0.00036921405,0.058124073,0.0016918986,0.0010946161,0.0010202134,0.00025297917,0.000038118047,0.9332112,0.0018878739,0.0012852808,0.00009689342],"study_design_scores_gemma":[0.0016637155,0.0002037976,0.87799025,0.00046777053,0.00031671094,8.275225e-8,0.000014941379,0.0024989129,0.10512987,0.000037307735,0.011016076,0.00066059624],"about_ca_topic_score_codex":0.000047361267,"about_ca_topic_score_gemma":0.000010763429,"teacher_disagreement_score":0.8280813,"about_ca_system_score_codex":0.00029978104,"about_ca_system_score_gemma":0.0007839297,"threshold_uncertainty_score":0.99976444},"labels":[],"label_agreement":null},{"id":"W3015324258","doi":"10.1016/j.jaci.2020.03.013","title":"The regulatory activity of autophagy in conjunctival fibroblasts and its possible role in vernal keratoconjunctivitis","year":2020,"lang":"en","type":"letter","venue":"Journal of Allergy and Clinical Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Ministero dell’Istruzione, dell’Università e della Ricerca","keywords":"Vernal keratoconjunctivitis; Autophagy; Keratoconjunctivitis; Cell biology; Conjunctiva; Biology; Medicine; Immunology; Dermatology; Genetics; Apoptosis","score_opus":0.018071902303459172,"score_gpt":0.2977386162006138,"score_spread":0.27966671389715464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3015324258","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8859223,0.016974613,0.0000032994567,0.09620816,0.0005072022,0.00021717555,0.0000070373785,0.0000058702526,0.00015432421],"genre_scores_gemma":[0.93703,0.021149049,0.000028230661,0.040035367,0.0012546199,0.000008390176,0.000005374155,0.000042291766,0.0004466697],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9972483,0.0006245538,0.0012460647,0.00029864686,0.00027067514,0.0003117616],"domain_scores_gemma":[0.99733776,0.0012466904,0.00095755944,0.00021307665,0.00013619797,0.00010872896],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005574458,0.0002687514,0.0012937293,0.00017561142,0.000059904174,0.000017119319,0.0002061611,0.00087893626,0.00006916095],"category_scores_gemma":[0.0003719366,0.00018782966,0.00029159355,0.00013535573,0.000553946,0.00013158424,0.00012204859,0.0034699014,0.0000025657887],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.16889602,0.007337149,0.0569523,0.001482162,0.05379022,0.05551675,0.0024876164,0.00004516288,0.06886758,0.003011123,0.20211835,0.37949556],"study_design_scores_gemma":[0.015465253,0.007417674,0.89124995,0.0011481969,0.00026162498,0.0011431922,0.00012314605,0.00029351734,0.0037264659,0.0036897045,0.07509597,0.00038527945],"about_ca_topic_score_codex":0.000025664343,"about_ca_topic_score_gemma":0.000035831912,"teacher_disagreement_score":0.83429766,"about_ca_system_score_codex":0.000054999757,"about_ca_system_score_gemma":0.00056541903,"threshold_uncertainty_score":0.9988291},"labels":[],"label_agreement":null},{"id":"W3015578999","doi":"10.5812/semj.102967","title":"The Role of Autophagy in Respiratory Complications of COVID-19","year":2020,"lang":"en","type":"article","venue":"Shiraz E-Medical Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autophagy; Chloroquine; Pneumonia; Medicine; Coronavirus disease 2019 (COVID-19); Respiratory system; Intensive care medicine; Virus; Acute respiratory distress; Immunology; Virology; Disease; Internal medicine; Lung; Biology; Infectious disease (medical specialty); Apoptosis; Malaria","score_opus":0.03429976856796279,"score_gpt":0.3484588032012379,"score_spread":0.3141590346332751,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3015578999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90407854,0.019488841,0.0018054177,0.0651314,0.00019499856,0.0004454613,0.000027933165,0.000049620034,0.008777779],"genre_scores_gemma":[0.988407,0.00038345784,0.00007004125,0.010844681,0.00025490162,0.000006057578,0.0000024988553,0.000010438977,0.000020904996],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983082,0.00013788253,0.00059467036,0.000112652495,0.0006653263,0.00018128786],"domain_scores_gemma":[0.9983869,0.0002814848,0.00021320168,0.00019354565,0.0000866204,0.00083822774],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006396873,0.000083423314,0.0002625203,0.00006280891,0.00009787197,0.0000073105566,0.00029947117,0.000096427575,0.00069777394],"category_scores_gemma":[0.0014709177,0.000054452652,0.000134386,0.00025832694,0.00034197982,0.000036047295,0.000043206564,0.00051256455,0.000015677417],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0057549286,0.003811016,0.26152804,0.0008568804,0.0014348949,0.002198,0.013912412,0.00018492302,0.09397032,0.103849955,0.05169775,0.46080086],"study_design_scores_gemma":[0.010786365,0.0015864137,0.32654354,0.00041301316,0.00016403482,0.00039390332,0.0032671157,0.0030282189,0.018300595,0.02748396,0.6077428,0.00029002613],"about_ca_topic_score_codex":0.000009766428,"about_ca_topic_score_gemma":0.00000556881,"teacher_disagreement_score":0.55604506,"about_ca_system_score_codex":0.000048820282,"about_ca_system_score_gemma":0.0015066318,"threshold_uncertainty_score":0.7640135},"labels":[],"label_agreement":null},{"id":"W3015644670","doi":"10.3390/cells9040908","title":"Targeting Autophagy Augments Berberine-Mediated Cell Death in Human Hepatoma Cells Harboring Hepatitis C Virus RNA","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute; Izaak Walton Killam Health Centre; Dalhousie University","funders":"Taipei Medical University Hospital; Ministry of Science and Technology, Taiwan","keywords":"Autophagy; Programmed cell death; Hepatitis C virus; Apoptosis; Berberine; Cell; Biology; RNA; Cell culture; Virus; Virology; RNA virus; Cancer research; Chemistry; Pharmacology; Biochemistry; Gene","score_opus":0.01672747128647442,"score_gpt":0.25924465518686285,"score_spread":0.24251718390038843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3015644670","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99558973,0.00095784053,0.00010463392,0.000117835225,0.0003369704,0.0005535225,0.000048905957,0.0004551095,0.0018354468],"genre_scores_gemma":[0.99547505,0.0007958167,0.0005381214,0.00207055,0.00039528994,0.00003888636,0.000086823486,0.00014050523,0.00045895853],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978593,0.00007605171,0.0005647373,0.00054573116,0.00037374446,0.0005804539],"domain_scores_gemma":[0.9989104,0.00006108695,0.00016268998,0.00031255683,0.00005178966,0.0005014713],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013299022,0.00034107338,0.00052238116,0.0001227052,0.00010962109,0.000035992252,0.00021825336,0.00015803547,0.0006862449],"category_scores_gemma":[0.000023011216,0.0003495435,0.00015308392,0.00033958198,0.000045518413,0.00013106251,0.00010198788,0.0003817308,0.0006968589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008947157,0.00032543298,0.019384438,0.00019827465,0.000056092773,0.0012556749,0.00073645095,0.000107649816,0.97605133,0.000016704178,0.0015308086,0.00024766938],"study_design_scores_gemma":[0.0028584367,0.00026758877,0.015687864,0.000095384035,0.00006498848,0.0000016974669,0.00003495803,0.004507356,0.97152567,0.00003281316,0.004588761,0.0003345087],"about_ca_topic_score_codex":0.00065068336,"about_ca_topic_score_gemma":0.000011501182,"teacher_disagreement_score":0.004525688,"about_ca_system_score_codex":0.00013576733,"about_ca_system_score_gemma":0.0001003524,"threshold_uncertainty_score":0.99989563},"labels":[],"label_agreement":null},{"id":"W3016415509","doi":"10.1096/fasebj.2020.34.s1.04070","title":"Nix induced mitochondrial fission and mitophagy inhibits myocyte insulin signaling through mTOR and p70S6 kinase","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Mitophagy; Lipotoxicity; Autophagy; Biology; Mitochondrial fission; Insulin resistance; Cell biology; Phosphatidic acid; Myocyte; PI3K/AKT/mTOR pathway; Insulin receptor; Mitochondrion; Internal medicine; Endocrinology; Insulin; Signal transduction; Biochemistry; Apoptosis; Phospholipid; Medicine","score_opus":0.0336324457764007,"score_gpt":0.2766040136645448,"score_spread":0.24297156788814409,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016415509","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890353,0.005329892,0.00021263647,0.004641361,0.00030822025,0.00026183136,0.000008770787,0.000037373447,0.00016459971],"genre_scores_gemma":[0.9912877,0.00067912607,0.0004925742,0.0051371995,0.002305661,0.000004053249,0.0000047046597,0.000028691791,0.00006026466],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987392,0.00013785303,0.0003245438,0.00022552395,0.00031706018,0.0002558438],"domain_scores_gemma":[0.9991193,0.00010456425,0.00015795266,0.00014794715,0.000067042725,0.000403235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015586361,0.00020128248,0.00030736436,0.00004259643,0.00034374258,0.000087418535,0.000106475774,0.00010943967,0.00022440124],"category_scores_gemma":[0.00015145425,0.00012715298,0.0000949557,0.0001480735,0.000097028635,0.00018629874,0.00007106247,0.00060369,0.000022425125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014938049,0.00006337387,0.00039455283,0.000035368786,0.000116160794,0.0003310456,0.0033814844,0.0000038050393,0.98746794,0.000048247675,0.00082233886,0.0058418447],"study_design_scores_gemma":[0.0066170082,0.0007567795,0.0019822456,0.00025594054,0.00018678432,0.00065933797,0.0008045929,0.00030820613,0.9852564,0.000728979,0.0022388194,0.00020493078],"about_ca_topic_score_codex":0.000011054775,"about_ca_topic_score_gemma":5.3265836e-7,"teacher_disagreement_score":0.0056369137,"about_ca_system_score_codex":0.000026713316,"about_ca_system_score_gemma":0.00013176039,"threshold_uncertainty_score":0.5185148},"labels":[],"label_agreement":null},{"id":"W3017004323","doi":"10.1096/fasebj.2020.34.s1.04594","title":"The absence of Lamp2 triggers autophagy and mitochondrial biogenesis in skeletal muscle","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Mitophagy; Autophagy; Cell biology; Lysosome; Mitochondrion; Autophagosome; Chemistry; LAMP1; Biogenesis; Biology; Intracellular; Endosome; Biochemistry; Enzyme; Apoptosis","score_opus":0.01687400860179479,"score_gpt":0.2591746542831091,"score_spread":0.24230064568131432,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3017004323","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918339,0.0039653764,0.00006533682,0.003596231,0.00019408578,0.00015596328,0.000007124865,0.0000097334405,0.00017223245],"genre_scores_gemma":[0.9974236,0.0013236165,0.00008371111,0.00063236034,0.00044427434,0.0000031341892,0.0000010091622,0.00001060927,0.00007766736],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991267,0.00009892933,0.00026431834,0.00009931737,0.0002330513,0.00017773452],"domain_scores_gemma":[0.99939585,0.00015323242,0.00011956441,0.00014208697,0.000037104466,0.00015216073],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022836842,0.00009315461,0.00018199543,0.00003435477,0.00015504601,0.000024888453,0.00016003384,0.00003934437,0.00009964957],"category_scores_gemma":[0.00010678078,0.000047896036,0.00011020686,0.00017587707,0.00019241299,0.000048909485,0.000027487144,0.00023189912,0.000008155055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011229817,0.00014767252,0.0036886693,0.000043016473,0.00026090504,0.000348763,0.0032685546,0.00003863145,0.9166764,0.0005463541,0.0014038493,0.07245418],"study_design_scores_gemma":[0.018791102,0.0021620889,0.36016047,0.00034023976,0.00042757447,0.0010222044,0.0048104976,0.0043409457,0.5824043,0.0033932242,0.021590507,0.00055681524],"about_ca_topic_score_codex":0.000016244903,"about_ca_topic_score_gemma":0.0000036333356,"teacher_disagreement_score":0.3564718,"about_ca_system_score_codex":0.000016936116,"about_ca_system_score_gemma":0.000121217025,"threshold_uncertainty_score":0.19531436},"labels":[],"label_agreement":null},{"id":"W3017115462","doi":"10.1096/fasebj.2020.34.s1.09352","title":"Autophagy and Heat Shock Protein 70 Expression During Acute Heat Stress in Isosmotic and Hyperosmotic Conditions in Peripheral Blood Mononuclear Cells from Young Adults: Preliminary Data","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Hsp70; Autophagy; Heat shock protein; Osmotic concentration; Peripheral blood mononuclear cell; Osmotic shock; Extracellular; Heat shock; Chemistry; Shock (circulatory); Cell biology; Andrology; Biology; Biochemistry; Internal medicine; Medicine; Apoptosis; In vitro","score_opus":0.014635813198145492,"score_gpt":0.24465617338861795,"score_spread":0.23002036019047245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3017115462","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947408,0.0032321564,0.00002285505,0.0010514604,0.00005873048,0.00057677174,0.00026844346,0.000029684568,0.000019138579],"genre_scores_gemma":[0.99816024,0.0008823585,0.00024341959,0.0003110866,0.00024114811,0.000013676392,0.00007831599,0.000036158686,0.000033585475],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998529,0.00017409482,0.00037915958,0.00036782314,0.00024174109,0.00030819236],"domain_scores_gemma":[0.99918467,0.00005139962,0.000060411716,0.00037640746,0.000022410473,0.00030471393],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012255982,0.00021976662,0.00034718373,0.00007922248,0.00021809456,0.00008447493,0.0002601342,0.00009012778,0.00020457417],"category_scores_gemma":[0.000029978903,0.00016059224,0.00004377968,0.00012610736,0.00011878413,0.0003637592,0.00022775875,0.0006485834,0.0000044865437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021180816,0.00036055563,0.016901622,0.000116457835,0.0001439687,0.0020769688,0.004736831,0.00024070468,0.97307533,0.0000022113836,0.00005711203,0.00017018085],"study_design_scores_gemma":[0.018002665,0.0014089275,0.3209914,0.0034336778,0.0005419173,0.0012892538,0.004601023,0.03319553,0.6158359,0.00025249558,0.0000063585912,0.00044086724],"about_ca_topic_score_codex":0.00011876897,"about_ca_topic_score_gemma":0.000014838655,"teacher_disagreement_score":0.3572394,"about_ca_system_score_codex":0.00004180489,"about_ca_system_score_gemma":0.000067079345,"threshold_uncertainty_score":0.6548762},"labels":[],"label_agreement":null},{"id":"W3017126457","doi":"10.1096/fasebj.2020.34.s1.04597","title":"Lysosomal Alterations in Skeletal Muscle Plasticity – An Investigation of Age, Exercise and Disuse","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Skeletal muscle; Lysosome; Autophagy; Internal medicine; Endocrinology; Intracellular; LAMP1; Denervation; Cathepsin; Biology; Mitochondrion; Chemistry; Medicine; Cell biology; Biochemistry; Endosome; Apoptosis","score_opus":0.027687110295853308,"score_gpt":0.2734439947980908,"score_spread":0.24575688450223748,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3017126457","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998352,0.0002122706,0.00019964366,0.0010297319,0.000029194098,0.00011742185,0.000007714641,0.000009522629,0.000042515767],"genre_scores_gemma":[0.9990291,0.0001140156,0.00019498002,0.00045996593,0.00017061886,0.0000025446193,0.000008493925,0.000007376227,0.000012890569],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99943507,0.000063708336,0.00019186975,0.000076218246,0.0001404589,0.00009268036],"domain_scores_gemma":[0.9995865,0.000036548077,0.00007267921,0.000068236855,0.0000300789,0.00020592142],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010149249,0.000065804845,0.00013514543,0.000040206265,0.00008146175,0.00002131921,0.000058242927,0.000026525102,0.00007624426],"category_scores_gemma":[0.000040066177,0.00004418228,0.000036570385,0.00010660343,0.000117055424,0.00014156968,0.000014327162,0.00019090119,0.0000028679785],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006901391,0.00031489148,0.05254963,0.00010086657,0.000096860495,0.0004898581,0.022598172,0.00043166793,0.9092027,0.0007710683,0.00024368626,0.012510482],"study_design_scores_gemma":[0.0033455647,0.00066674274,0.88418835,0.00024251243,0.00019528734,0.00012457615,0.001332339,0.008067162,0.09941007,0.0022649993,0.000028598915,0.00013376561],"about_ca_topic_score_codex":0.000011835644,"about_ca_topic_score_gemma":0.0000066527373,"teacher_disagreement_score":0.83163875,"about_ca_system_score_codex":0.000010768428,"about_ca_system_score_gemma":0.00006695768,"threshold_uncertainty_score":0.18017012},"labels":[],"label_agreement":null},{"id":"W3017130233","doi":"10.1096/fasebj.2020.34.s1.04555","title":"Blunted Autophagy and Heat Shock Responses in Peripheral Blood Mononuclear Cells of Elderly Adults During Prolonged, Extreme‐Heat Exposure","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Heat shock; Heat shock protein; Autophagy; Peripheral blood mononuclear cell; Andrology; Shock (circulatory); Medicine; Extreme heat; Western blot; Internal medicine; Endocrinology; Immunology; Physiology; Biology; Gene; Apoptosis; Biochemistry; In vitro","score_opus":0.015923721566018338,"score_gpt":0.23491262597464962,"score_spread":0.21898890440863128,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3017130233","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99355,0.004505123,0.000011228744,0.001397162,0.000065558794,0.00033617642,0.000013021964,0.00003411228,0.000087590255],"genre_scores_gemma":[0.9981711,0.0007100512,0.00012605477,0.0004863136,0.00029248797,0.0000059030845,0.0000017263916,0.000034187076,0.00017218395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985321,0.00021981308,0.00042958316,0.00021380279,0.00030258074,0.00030208193],"domain_scores_gemma":[0.9992868,0.000063160085,0.0000816152,0.000215371,0.00007108258,0.00028197264],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023460947,0.00019713456,0.00037411967,0.000092627444,0.00014552008,0.000033516422,0.00016288688,0.0000918289,0.00033261147],"category_scores_gemma":[0.000058073245,0.00013592343,0.00012599105,0.00018437662,0.00011820514,0.00011882831,0.000045480745,0.0005412966,0.0000054585366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01254745,0.0002606245,0.014111973,0.00013826838,0.0002033688,0.0011451761,0.008001075,0.0001262042,0.9621822,0.0000054893294,0.000059210623,0.0012189614],"study_design_scores_gemma":[0.014192814,0.0033323593,0.14689669,0.0005607999,0.0002597692,0.0013901249,0.0023965177,0.0019248178,0.82869095,0.000053036594,0.00005992068,0.00024218197],"about_ca_topic_score_codex":0.000025178193,"about_ca_topic_score_gemma":0.000005900715,"teacher_disagreement_score":0.13349123,"about_ca_system_score_codex":0.000030778312,"about_ca_system_score_gemma":0.00011787557,"threshold_uncertainty_score":0.5542797},"labels":[],"label_agreement":null},{"id":"W3017206848","doi":"10.1016/j.tcb.2020.03.004","title":"Noncanonical Cell Fate Regulation by Bcl-2 Proteins","year":2020,"lang":"en","type":"review","venue":"Trends in Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Medical Research Council; Institut National Du Cancer; Institut Universitaire de France; Ligue Contre le Cancer; Fondation pour la Recherche Médicale; Institut Gustave-Roussy; Fondation Leducq; Ministry of Health, British Columbia; Association pour la Recherche sur le Cancer; Stand Up To Cancer; Ministry of Education; Leukemia and Lymphoma Society; U.S. Department of Defense","keywords":"Biology; Cell biology; Autophagy; Cell fate determination; Apoptosis; Programmed cell death; Mitochondrion; Bcl-2 family; Bioenergetics; Genetics; Transcription factor; Gene","score_opus":0.04489926768673344,"score_gpt":0.36438064207199183,"score_spread":0.31948137438525837,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3017206848","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00005249063,0.97300035,0.000023791868,0.00011996747,0.00018289823,0.00057335384,0.00013383535,0.000073153155,0.025840154],"genre_scores_gemma":[0.0010882664,0.9878592,0.00016860048,0.00019352327,0.00032913248,0.000184338,0.0028161833,0.000063800646,0.0072969524],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979251,0.00028859312,0.00067169825,0.0006390727,0.000105433515,0.00037012028],"domain_scores_gemma":[0.99895966,0.00009113173,0.0003021175,0.0004482657,0.000017667377,0.0001811387],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00012657889,0.00042417352,0.0017552909,0.00025740458,0.000029475003,0.0000069003245,0.00022126376,0.0007965697,0.0013740115],"category_scores_gemma":[0.000011987051,0.00031923177,0.00043670548,0.0004805097,0.00011248341,0.000018936373,0.000065769535,0.00063263834,0.00034504963],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005496643,0.00024184537,0.0000071244967,0.0024638502,0.00006157741,0.000075597694,0.000025653108,1.11654835e-7,0.00044031627,0.00005472303,0.0034550626,0.9931192],"study_design_scores_gemma":[0.0010148048,0.00044178386,0.000014585624,0.0007581929,0.00035753095,0.0000111715535,0.0000019922832,0.000013297265,0.00042603552,0.00004897518,0.99664366,0.00026798647],"about_ca_topic_score_codex":0.000019489216,"about_ca_topic_score_gemma":0.0000033476808,"teacher_disagreement_score":0.99318856,"about_ca_system_score_codex":0.00014645795,"about_ca_system_score_gemma":0.0002777142,"threshold_uncertainty_score":0.999926},"labels":[],"label_agreement":null},{"id":"W3017312796","doi":"10.1096/fasebj.2020.34.s1.04613","title":"Enhanced Mitochondrial Turnover in Aged Human Right Atrial Tissue","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"York University","funders":"","keywords":"Mitophagy; Mitochondrion; Autophagy; Medicine; Myocardial infarction; Dyslipidemia; Internal medicine; Ischemia; Coronary artery disease; Oxidative phosphorylation; Stroke (engine); Cardiology; Disease; Endocrinology; Physiology; Biology; Cell biology; Apoptosis; Biochemistry","score_opus":0.019353237326366873,"score_gpt":0.29383733133013556,"score_spread":0.2744840940037687,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3017312796","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945696,0.0005348643,0.00041525663,0.0021211735,0.0006365647,0.00027824825,0.0000051107745,0.000028595296,0.0014105897],"genre_scores_gemma":[0.9911834,0.000053943902,0.00007875743,0.001674639,0.0064252075,0.0000026728055,0.0000075659736,0.000020299864,0.0005535407],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988236,0.00013648873,0.0003252509,0.0001440167,0.00032418148,0.00024647545],"domain_scores_gemma":[0.99937415,0.000049163118,0.00012187927,0.00017306629,0.000033168108,0.00024857963],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016106787,0.00013720391,0.00026636285,0.000051290845,0.00017953492,0.000042047195,0.00019873478,0.00007305613,0.0028591985],"category_scores_gemma":[0.000057654568,0.00008407835,0.00019087194,0.00016587939,0.00006669486,0.00008394573,0.000019924848,0.00064811524,0.00013873629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016560083,0.00006466309,0.00019645305,0.000008880466,0.00011970533,0.00063100975,0.0024996721,0.000024370478,0.9905317,0.00011192306,0.003265392,0.0008902355],"study_design_scores_gemma":[0.01541107,0.00082009606,0.007120747,0.00010361141,0.0002109516,0.00023981731,0.00018956675,0.000050128307,0.9678012,0.0012515401,0.0065857503,0.00021550461],"about_ca_topic_score_codex":0.000008633613,"about_ca_topic_score_gemma":0.000009573005,"teacher_disagreement_score":0.02273047,"about_ca_system_score_codex":0.000051363535,"about_ca_system_score_gemma":0.00009941474,"threshold_uncertainty_score":0.9980523},"labels":[],"label_agreement":null},{"id":"W3019462745","doi":"10.1096/fasebj.2020.34.s1.07607","title":"Mechanism of Activation of the Ubiquitin E3 Ligase, Parkin","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University","funders":"","keywords":"Parkin; Mitophagy; PINK1; Ubiquitin ligase; Ubiquitin; Cell biology; Mitochondrion; Chemistry; Biochemistry; Biology; Autophagy; Parkinson's disease; Medicine; Apoptosis; Disease","score_opus":0.025560343181035988,"score_gpt":0.261017346504636,"score_spread":0.2354570033236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3019462745","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99057955,0.00014349598,0.0008600999,0.0073141893,0.000065698914,0.00012770404,0.000007316511,0.0000071161794,0.0008948467],"genre_scores_gemma":[0.9975222,0.000060153532,0.00005168403,0.0019831078,0.0002666142,0.0000013390871,0.0000013096849,0.000008788357,0.0001048177],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992994,0.00007820562,0.00021492716,0.000051517214,0.0002672446,0.000088716195],"domain_scores_gemma":[0.9994229,0.000047372574,0.00023309188,0.0001515951,0.0000704472,0.00007459959],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020256528,0.00006213282,0.00014282698,0.000018761099,0.000072507755,0.000005158134,0.00015917575,0.000030526386,0.00032812238],"category_scores_gemma":[0.000079304016,0.000030603034,0.00013426975,0.00012830905,0.00005499208,0.000036597947,0.000026656346,0.00021709273,0.000006020054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035176356,0.00006750426,0.0003914557,0.000027855984,0.00013972225,0.000008024742,0.0012971684,0.000020499645,0.9913589,0.0032372342,0.0009954688,0.0021044533],"study_design_scores_gemma":[0.00079804315,0.00014813732,0.004086828,0.000102433856,0.00009696507,0.000043249394,0.00037723867,0.00022029616,0.99103284,0.002840077,0.00022451387,0.000029385],"about_ca_topic_score_codex":0.0000028674708,"about_ca_topic_score_gemma":1.05760776e-7,"teacher_disagreement_score":0.006942653,"about_ca_system_score_codex":0.000012655604,"about_ca_system_score_gemma":0.00010856735,"threshold_uncertainty_score":0.359271},"labels":[],"label_agreement":null},{"id":"W3022096158","doi":"10.1016/s0022-3182(00)70551-6","title":"","year":2000,"lang":"en","type":"article","venue":"Journal of Nutrition Education","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"CD80; Autophagy; Calcitriol receptor; CD86; Immune system; Endocrinology; Vitamin; Vitamin D and neurology; Lipopolysaccharide; Bone marrow; Stimulation; Dendritic cell; Internal medicine; Biology; Calcitriol; Receptor; Chemistry; Cell biology; In vitro; T cell; CD40; Immunology; Biochemistry; Medicine; Cytotoxic T cell","score_opus":0.008519983852255974,"score_gpt":0.3100154685671736,"score_spread":0.3014954847149176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3022096158","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98418856,0.0038836892,0.00006799527,0.010771161,0.00036697945,0.0003018664,0.0000013339321,0.000014462969,0.00040397816],"genre_scores_gemma":[0.98802847,0.0034311712,0.002718382,0.003248113,0.0021687432,0.000029517454,0.000016360584,0.0000120035465,0.00034725477],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9988216,0.000056802353,0.00056477205,0.00008850331,0.0003402623,0.00012804953],"domain_scores_gemma":[0.9987173,0.000035300473,0.00028033828,0.00015079805,0.0005474379,0.00026879727],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021120801,0.00009716837,0.00024974832,0.00024171344,0.00007158051,0.000022680479,0.00007100565,0.00006645435,0.00090608525],"category_scores_gemma":[0.00004209459,0.00008317174,0.00022227486,0.00025431585,0.000035022997,0.00048980425,0.000001500302,0.00018989466,0.000012326419],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0060310382,0.055032168,0.0136983525,0.00038000158,0.00032418812,0.00011004341,0.001823689,0.000026150332,0.050660837,0.00042955982,0.019298151,0.85218585],"study_design_scores_gemma":[0.013672095,0.0034921814,0.7673412,0.0018436058,0.0005356664,0.007522676,0.0033399991,0.00003294676,0.0471795,0.014923739,0.13987261,0.00024379506],"about_ca_topic_score_codex":0.000004140041,"about_ca_topic_score_gemma":2.3274086e-7,"teacher_disagreement_score":0.851942,"about_ca_system_score_codex":0.00012926631,"about_ca_system_score_gemma":0.0005449696,"threshold_uncertainty_score":0.9920998},"labels":[],"label_agreement":null},{"id":"W3023571997","doi":"10.3390/ijms21093162","title":"Investigating Programmed Cell Death and Tumor Invasion in a Three-Dimensional (3D) Microfluidic Model of Glioblastoma","year":2020,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba; Queen's University; University of Victoria","funders":"British Columbia Knowledge Development Fund; Natural Sciences and Engineering Research Council of Canada; BC Cancer Foundation; Research Manitoba; National Institute for Medical Research Development; University of Victoria","keywords":"Autophagy; Temozolomide; Apoptosis; Programmed cell death; Gene knockdown; Cancer research; Glioma; U87; Cell culture; Cell; Chemistry; Biology; Biochemistry","score_opus":0.0303671146137061,"score_gpt":0.28501170433764456,"score_spread":0.25464458972393844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3023571997","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99409086,0.0022030282,0.0014017732,0.0020983806,0.000050861414,0.000087378154,0.0000024467474,0.0000041313842,0.00006114489],"genre_scores_gemma":[0.9877949,0.000045262426,0.010112445,0.0020005852,0.000038043658,0.0000012846613,6.225652e-7,0.0000053038248,0.0000015608509],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986978,0.000026786594,0.00035654535,0.00013425875,0.0006829812,0.00010158682],"domain_scores_gemma":[0.99931604,0.000032890013,0.00025679503,0.000038799448,0.00020969348,0.00014577755],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002872181,0.00007950456,0.00017257417,0.00017251185,0.000023172712,0.000022067123,0.0002120105,0.000024356603,0.000010152538],"category_scores_gemma":[0.0001269576,0.00006146241,0.00006821425,0.00016977171,0.00018444295,0.000127619,0.000060951483,0.0001255406,7.158255e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022092315,0.00016050784,0.025398994,0.000027550434,0.000047299025,0.00039886995,0.0004107285,0.0018501012,0.9687534,0.00029200735,0.000032518332,0.0024070796],"study_design_scores_gemma":[0.00303104,0.0014423471,0.0077383695,0.0005235587,0.0000466619,0.0003655313,0.00014202889,0.1482797,0.83386254,0.0044117807,0.000025922183,0.0001305549],"about_ca_topic_score_codex":0.000012964503,"about_ca_topic_score_gemma":0.0000015923316,"teacher_disagreement_score":0.14642958,"about_ca_system_score_codex":0.000021216376,"about_ca_system_score_gemma":0.00037451138,"threshold_uncertainty_score":0.25063643},"labels":[],"label_agreement":null},{"id":"W3024379713","doi":"10.1101/2020.05.12.092072","title":"The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; University of Ottawa","keywords":"Aggresome; Proteotoxicity; Protein aggregation; Cell biology; Stress granule; Proteasome; Cytosol; TFEB; Autophagy; Ubiquitin; Chemistry; Biology; Translation (biology); Apoptosis; Biochemistry; Messenger RNA","score_opus":0.015639532948190243,"score_gpt":0.23959816706648748,"score_spread":0.22395863411829725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3024379713","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9606367,0.02928727,0.000096806376,0.0060625705,0.00060136523,0.0027553504,0.00013567637,0.00038989913,0.000034371176],"genre_scores_gemma":[0.99556994,0.0016946082,0.0003652033,0.0010098252,0.00066220533,0.00051200285,3.970105e-7,0.00015444982,0.000031337004],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968292,0.00026817402,0.00076403,0.00083771726,0.00069225486,0.0006086128],"domain_scores_gemma":[0.9961615,0.00016055431,0.0007626256,0.0021250583,0.0004329466,0.00035729085],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006363325,0.0006207623,0.0008400534,0.00010898732,0.00036224045,0.00013536379,0.0009707109,0.00041051273,0.00006440805],"category_scores_gemma":[0.000472159,0.00039780294,0.00046300038,0.00065790926,0.00057019875,0.000077215205,0.00035935544,0.001247417,0.00010059315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018346241,0.000778803,0.0011548649,0.0023936378,0.0020551768,0.00060445315,0.0001234074,0.00003551396,0.9816511,0.008114502,0.0011308622,0.00012305271],"study_design_scores_gemma":[0.0021881668,0.00030942392,0.061999973,0.0015335775,0.0005789177,8.9671204e-8,0.000017867742,0.0007624049,0.9060386,0.000055102093,0.025786962,0.00072893756],"about_ca_topic_score_codex":0.000035585646,"about_ca_topic_score_gemma":8.94919e-7,"teacher_disagreement_score":0.07561252,"about_ca_system_score_codex":0.00014832454,"about_ca_system_score_gemma":0.001196923,"threshold_uncertainty_score":0.9998474},"labels":[],"label_agreement":null},{"id":"W3025245999","doi":"10.21037/atm-20-2930","title":"Treatment response in triple-negative breast cancer: a role for eEF2 kinase-mediated autophagy?","year":2020,"lang":"en","type":"letter","venue":"Annals of Translational Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; Canada's Michael Smith Genome Sciences Centre","funders":"Canadian Institutes of Health Research; Simon Fraser University","keywords":"Autophagy; Triple-negative breast cancer; Breast cancer; Kinase; Triple negative; Cancer research; Cancer; Medicine; Biology; Bioinformatics; Internal medicine; Genetics; Apoptosis","score_opus":0.06107162801425565,"score_gpt":0.3617464298317567,"score_spread":0.30067480181750106,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3025245999","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.014187249,0.007848683,0.000054940785,0.96994597,0.00024579384,0.0022366636,0.00521773,0.00006607194,0.0001968877],"genre_scores_gemma":[0.23870276,0.003365496,0.00035017432,0.74210423,0.0061845225,0.0012224908,0.0064825434,0.00017803746,0.0014097573],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9970163,0.0002266713,0.0009426115,0.000594245,0.0007605673,0.00045956898],"domain_scores_gemma":[0.99697155,0.0017086776,0.00036446366,0.00031853723,0.0004055216,0.00023122516],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00025660126,0.0005342239,0.0014434723,0.00052135217,0.000056550114,0.0000048992183,0.00017653835,0.0004763455,0.0009170844],"category_scores_gemma":[0.00026512123,0.00041297637,0.0004312504,0.00048438084,0.0002943015,0.00008083808,0.0000070618553,0.00058515166,0.000011925943],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.124903746,0.0012908068,0.0012451637,0.0018170297,0.004218406,0.0029691479,0.006831352,0.000069665126,0.009224094,0.00014026706,0.8174112,0.029879145],"study_design_scores_gemma":[0.06433119,0.014081138,0.11955124,0.005244529,0.0022052417,0.00016925548,0.00030258714,0.0037982115,0.013880017,0.009072851,0.7660022,0.0013615642],"about_ca_topic_score_codex":0.0004002718,"about_ca_topic_score_gemma":0.00001713076,"teacher_disagreement_score":0.22784176,"about_ca_system_score_codex":0.000092197,"about_ca_system_score_gemma":0.0010250628,"threshold_uncertainty_score":0.9999962},"labels":[],"label_agreement":null},{"id":"W3025992023","doi":"10.4103/0972-4052.244604","title":"OSC15: Tas1r1/Tas1r3 umami receptor expression levels are decreased in a serum starved muscle fiber model of atrophy","year":2018,"lang":"en","type":"article","venue":"The Journal of Indian Prosthodontic Society","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Shriners Hospitals for Children - Canada","funders":"","keywords":"Skeletal muscle; Myocyte; C2C12; Internal medicine; Endocrinology; Myogenesis; Biology; Cell biology; Chemistry; Medicine","score_opus":0.03477602304545514,"score_gpt":0.2919282518647997,"score_spread":0.2571522288193446,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3025992023","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99721056,0.0006502201,0.0007517961,0.00065971114,0.00012538247,0.0004484078,0.00005993996,0.0000152060775,0.00007876936],"genre_scores_gemma":[0.9881022,0.00018137372,0.0101298895,0.0009161261,0.00031663466,0.000006086902,0.0000038343805,0.000041722848,0.00030212864],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99792206,0.000280583,0.0007348976,0.00016589342,0.0005443509,0.0003521851],"domain_scores_gemma":[0.9979836,0.00017948031,0.00078566646,0.00042378393,0.00038597113,0.00024153331],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014505697,0.00022187717,0.0005571191,0.0000875707,0.00013390371,0.000015614207,0.00030391655,0.00018762398,0.00049429527],"category_scores_gemma":[0.0001723123,0.00014239465,0.00043419743,0.00031043866,0.00032095134,0.00018851069,0.000043945023,0.00048552,0.000016036578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0059454553,0.0017725694,0.018170554,0.0006664985,0.0008726417,0.00011795088,0.06287955,0.0003453113,0.87948704,0.000020167932,0.018134318,0.011587953],"study_design_scores_gemma":[0.019271579,0.0031760582,0.2705644,0.004556911,0.00072947645,0.00024749213,0.011440345,0.003400367,0.68232214,0.0024141073,0.001133505,0.0007436054],"about_ca_topic_score_codex":0.000019116253,"about_ca_topic_score_gemma":0.0000049316077,"teacher_disagreement_score":0.25239384,"about_ca_system_score_codex":0.00013869768,"about_ca_system_score_gemma":0.00043846038,"threshold_uncertainty_score":0.58066857},"labels":[],"label_agreement":null},{"id":"W3026814869","doi":"10.1186/s13048-020-00660-5","title":"Activated CAMKKβ-AMPK signaling promotes autophagy in a spheroid model of ovarian tumour metastasis","year":2020,"lang":"en","type":"article","venue":"Journal of Ovarian Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"China Scholarship Council; Ovarian Cancer Canada; Cancer Research Society","keywords":"Autophagy; Spheroid; AMPK; Cell biology; Viability assay; Chemistry; Cancer research; Protein kinase A; Cell; Apoptosis; Biology; Kinase; In vitro; Biochemistry","score_opus":0.15474933862416496,"score_gpt":0.39074737227010337,"score_spread":0.2359980336459384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3026814869","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99035823,0.0007485822,0.0022355146,0.00539508,0.000045887566,0.00047676943,0.0000180504,0.000018192974,0.00070367765],"genre_scores_gemma":[0.9914793,0.00008701812,0.0077141095,0.0002639171,0.00028431436,0.000007914454,0.0000041027456,0.000047891997,0.000111435664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99631196,0.0004724022,0.0009717493,0.0002768492,0.0014298196,0.0005372281],"domain_scores_gemma":[0.9977504,0.00025948047,0.00036792926,0.00026963803,0.0007741721,0.0005783989],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002357471,0.00020187553,0.00079855893,0.0005459847,0.00008654651,0.000044514378,0.00040668098,0.00015177013,0.0006923787],"category_scores_gemma":[0.0009598083,0.00016308436,0.00028092673,0.0011359215,0.00013214994,0.00026822006,0.000097191994,0.0013603008,0.0000131844845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040182457,0.0007501384,0.00060551876,0.00026250907,0.00053774647,0.0014052491,0.0023874994,0.0017826917,0.9842929,0.0007938508,0.0004261345,0.0027375156],"study_design_scores_gemma":[0.00783657,0.002051498,0.0060560005,0.0006150034,0.00016527183,0.00018848009,0.0010332394,0.03270104,0.9445698,0.0043853843,0.00017607634,0.000221582],"about_ca_topic_score_codex":0.00008586816,"about_ca_topic_score_gemma":0.000002729187,"teacher_disagreement_score":0.039723046,"about_ca_system_score_codex":0.00015769867,"about_ca_system_score_gemma":0.0015976032,"threshold_uncertainty_score":0.75810605},"labels":[],"label_agreement":null},{"id":"W3028965142","doi":"10.1080/15548627.2020.1761659","title":"Using Reactome to build an autophagy mechanism knowledgebase","year":2020,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"National Human Genome Research Institute; European Bioinformatics Institute; Foundation for the National Institutes of Health","keywords":"Autophagy; Biology; Computational biology; PI3K/AKT/mTOR pathway; Cell biology; Sequestosome 1; Signal transduction; Genetics","score_opus":0.09045085359650998,"score_gpt":0.3660516334232336,"score_spread":0.2756007798267236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3028965142","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98708874,0.00064384675,0.006181094,0.0015735275,0.0004442901,0.00075176446,0.000032670283,0.0006927837,0.0025912712],"genre_scores_gemma":[0.97316504,0.000021980915,0.0075284974,0.017352927,0.0010727566,0.000035092322,0.000043216798,0.00011380465,0.00066668575],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99767053,0.00009569545,0.00044502714,0.00075033976,0.000436421,0.0006019653],"domain_scores_gemma":[0.99754494,0.000043071108,0.00010225633,0.0007043685,0.00015265284,0.0014527352],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00017631381,0.00038321482,0.00059522,0.0001775641,0.00015577649,0.000051735162,0.0003055925,0.00019754817,0.0017213258],"category_scores_gemma":[0.00014581208,0.00036461573,0.00021557312,0.00061787106,0.00005317588,0.00026424043,0.0001232888,0.00031205744,0.0010576714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00096388004,0.0009224829,0.00022794712,0.0001829464,0.00031635063,0.0020456123,0.0033842518,0.000086158965,0.9511945,0.020661676,0.0018914844,0.018122658],"study_design_scores_gemma":[0.0051989695,0.0028648826,0.008529132,0.00016082446,0.00046879437,0.00025686747,0.0002948112,0.02677745,0.9125937,0.0039660726,0.037846047,0.0010424387],"about_ca_topic_score_codex":0.000058004352,"about_ca_topic_score_gemma":0.000002865251,"teacher_disagreement_score":0.03860084,"about_ca_system_score_codex":0.00012617247,"about_ca_system_score_gemma":0.00033154452,"threshold_uncertainty_score":0.99988055},"labels":[],"label_agreement":null},{"id":"W3030162121","doi":"10.1002/cncr.32985","title":"Elimination of dormant, autophagic ovarian cancer cells and xenografts through enhanced sensitivity to anaplastic lymphoma kinase inhibition","year":2020,"lang":"en","type":"article","venue":"Cancer","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Foundation for Pharmacy; National Center for Advancing Translational Sciences; National Cancer Institute; Anne and Harry Zarrow Foundation; National Foundation for Cancer Research","keywords":"Autophagy; Crizotinib; Cancer research; Small interfering RNA; Cancer cell; Medicine; Ovarian cancer; Programmed cell death; Anaplastic lymphoma kinase; Apoptosis; Cancer; Gene knockdown; Biology; Cell culture; Pathology; Lung cancer; Transfection; Internal medicine","score_opus":0.01872992460281537,"score_gpt":0.28832708350949227,"score_spread":0.2695971589066769,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3030162121","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926571,0.0012612856,0.0029584148,0.0020103029,0.00023731397,0.00040278153,0.00011756354,0.00005551575,0.0002996982],"genre_scores_gemma":[0.9944959,0.0006268778,0.00022781442,0.004127104,0.0003604209,0.00006340262,0.000020075766,0.000021045316,0.00005736018],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991114,0.00003717745,0.00019595245,0.00028081768,0.00019127832,0.00018335148],"domain_scores_gemma":[0.99942976,0.000035640558,0.000093309274,0.00012811295,0.00011872779,0.00019445737],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005250142,0.0001486262,0.00027367653,0.00004656488,0.000051392002,0.000009967347,0.000024309564,0.00007140682,0.00024436237],"category_scores_gemma":[0.000026119236,0.0001383925,0.000053144307,0.00027725226,0.00006291351,0.00012774876,0.000026965792,0.000059903414,0.000014023506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011402741,0.00012670894,0.00022952714,0.0003750347,0.000120715726,0.00009792409,0.0034736653,0.0002640335,0.9498301,0.00020518168,0.0010595571,0.04307725],"study_design_scores_gemma":[0.0023214594,0.00033431296,0.047427364,0.00026575846,0.00017006307,0.000004049628,0.000097446195,0.0013451609,0.94664174,0.000056730598,0.0011794703,0.00015645863],"about_ca_topic_score_codex":0.0002160772,"about_ca_topic_score_gemma":0.000049837672,"teacher_disagreement_score":0.047197837,"about_ca_system_score_codex":0.00010196165,"about_ca_system_score_gemma":0.00015486311,"threshold_uncertainty_score":0.5643482},"labels":[],"label_agreement":null},{"id":"W3033397665","doi":"","title":"Inhibiting ULK1 kinase decreases autophagy and cell viability in high-grade serous ovarian cancer spheroids.","year":2020,"lang":"en","type":"article","venue":"PubMed","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ovarian Cancer Canada; Western University","funders":"","keywords":"Autophagy; Cancer research; ULK1; Ovarian cancer; Gene knockdown; Spheroid; Viability assay; Chemistry; Cancer cell; Biology; Kinase; Cell biology; Protein kinase A; Cell; Cancer; Medicine; Cell culture; Internal medicine; Apoptosis; AMPK; Biochemistry","score_opus":0.020757409339102258,"score_gpt":0.2401637605744529,"score_spread":0.21940635123535066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033397665","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99241734,0.003147227,0.00002412918,0.0026195562,0.00009204444,0.0010479251,0.000024880574,0.00013088854,0.0004960068],"genre_scores_gemma":[0.9945143,0.000269216,0.00018278898,0.0037910538,0.00032577748,0.0007619359,0.000017800452,0.000032627413,0.000104490704],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99854684,0.0000764952,0.00029504858,0.00043729527,0.0002020736,0.0004422606],"domain_scores_gemma":[0.99904,0.000080806516,0.00007633043,0.00019666356,0.000032511613,0.0005736673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016965419,0.00019634455,0.00035604977,0.00004560549,0.000054426004,0.000027505967,0.00007708142,0.00009835675,0.00017183521],"category_scores_gemma":[0.00014019833,0.00018077172,0.00006669826,0.00028084288,0.00008331097,0.000104055245,0.00004362834,0.00021860245,0.0000070231295],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024573866,0.0028314588,0.54419416,0.0015993188,0.0002719992,0.0021614,0.0034827508,0.000101396596,0.015919998,0.0005312906,0.0013340638,0.42511478],"study_design_scores_gemma":[0.0045875665,0.00007773495,0.9066319,0.000032641306,0.000090190006,0.0000070891265,0.00012696387,0.0002734009,0.08632895,0.00041461183,0.0012139241,0.00021506322],"about_ca_topic_score_codex":0.0009878519,"about_ca_topic_score_gemma":0.000080079546,"teacher_disagreement_score":0.42489973,"about_ca_system_score_codex":0.00010128707,"about_ca_system_score_gemma":0.00009207405,"threshold_uncertainty_score":0.7371657},"labels":[],"label_agreement":null},{"id":"W3033409553","doi":"10.1016/j.mehy.2020.109952","title":"How does autophagy fine-tune immune-evasion of pancreatic ductal adenocarcinoma cells?","year":2020,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Autophagy; Pancreatic ductal adenocarcinoma; Immune system; Evasion (ethics); Pancreatic carcinoma; Adenocarcinoma; Biology; Cancer research; Cell biology; Medicine; Internal medicine; Pancreatic cancer; Immunology; Apoptosis; Cancer; Biochemistry","score_opus":0.023945157136974732,"score_gpt":0.24563302325251354,"score_spread":0.2216878661155388,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033409553","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9784789,0.0076683643,0.00025991676,0.012269355,0.0002415377,0.00032869237,0.000023165592,0.00013812212,0.0005919436],"genre_scores_gemma":[0.99555,0.00054571254,0.00038487275,0.0017542279,0.00063744327,0.00002104753,0.00001936257,0.00004469009,0.0010426897],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99784046,0.000095822725,0.0004050838,0.00036297977,0.0009597083,0.00033591836],"domain_scores_gemma":[0.9984704,0.0003021225,0.00013960955,0.00037934058,0.00007377713,0.0006347399],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016587846,0.00024770256,0.0006879229,0.000067881134,0.000059782476,0.000019646473,0.00027454126,0.00019668616,0.002889533],"category_scores_gemma":[0.0011345817,0.00015500102,0.00027128783,0.00023897405,0.0003368425,0.00009125147,0.00009138012,0.00030072662,0.00007885192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004105358,0.0029306356,0.061827444,0.0038035347,0.002020358,0.007882208,0.0047576753,0.0000033733174,0.8447495,0.002570678,0.008644424,0.05670481],"study_design_scores_gemma":[0.0048188195,0.0015589849,0.11975004,0.00063381495,0.0005588108,0.00013914639,0.00078398973,0.0009889507,0.8621582,0.0008838707,0.0073096254,0.0004157476],"about_ca_topic_score_codex":0.000028873203,"about_ca_topic_score_gemma":0.0000016301892,"teacher_disagreement_score":0.05792259,"about_ca_system_score_codex":0.000023133329,"about_ca_system_score_gemma":0.0002340836,"threshold_uncertainty_score":0.99802196},"labels":[],"label_agreement":null},{"id":"W3033491714","doi":"10.1080/15548627.2020.1775394","title":"Puncta intended: connecting the dots between autophagy and cell stress networks","year":2020,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Terry Fox Research Institute; University of British Columbia; Canada's Michael Smith Genome Sciences Centre; Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canada's Michael Smith Genome Sciences Centre","keywords":"Autophagy; Biology; Cell biology; Stress (linguistics); Cell; Genetics; Apoptosis","score_opus":0.02126525292493286,"score_gpt":0.2564329243416526,"score_spread":0.23516767141671974,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3033491714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9822003,0.006446039,0.0020875956,0.0036774294,0.00027774708,0.0005973743,0.000030742664,0.00035591604,0.004326851],"genre_scores_gemma":[0.9918782,0.00019965443,0.00017025015,0.006076668,0.0011426561,0.000020979434,0.000051919036,0.00006039268,0.00039928048],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.998276,0.00010125647,0.0003800645,0.0004930488,0.00027852287,0.00047108313],"domain_scores_gemma":[0.9986132,0.00031701836,0.00015107689,0.00041622322,0.000072618735,0.00042987824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001924071,0.0003074815,0.00048698703,0.00004502225,0.00026447285,0.00007609498,0.00025544062,0.00017339563,0.0006607893],"category_scores_gemma":[0.00011323927,0.00021219478,0.00015328736,0.00027279282,0.00014901288,0.00011645127,0.00017664213,0.00053716754,0.0000721661],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030078671,0.0017216371,0.12126963,0.0024604856,0.005067709,0.0049500526,0.030549793,0.0019978064,0.044255696,0.01612297,0.034635786,0.73396057],"study_design_scores_gemma":[0.017072003,0.0030265371,0.5285484,0.00051142165,0.0023045843,0.00028891346,0.0043707835,0.07182548,0.30154252,0.0026392152,0.06576176,0.0021083378],"about_ca_topic_score_codex":0.000042923028,"about_ca_topic_score_gemma":0.0000023962978,"teacher_disagreement_score":0.73185223,"about_ca_system_score_codex":0.00003050224,"about_ca_system_score_gemma":0.00007858594,"threshold_uncertainty_score":0.8653052},"labels":[],"label_agreement":null},{"id":"W3034767506","doi":"10.3390/cells9061454","title":"Parkin Overexpression Attenuates Sepsis-Induced Muscle Wasting","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre; Institut Universitaire de Gériatrie de Montréal; Université du Québec à Montréal","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Parkin; Atrophy; Muscle atrophy; Sepsis; Mitophagy; Mitochondrion; Autophagy; PINK1; Endocrinology; Internal medicine; Biology; Medicine; Cell biology; Apoptosis; Parkinson's disease; Biochemistry; Disease","score_opus":0.03874390186540658,"score_gpt":0.27809634700129887,"score_spread":0.2393524451358923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3034767506","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932742,0.0003399539,0.00004732683,0.001511473,0.00009625001,0.00016396068,0.0000049043533,0.000113504255,0.00444841],"genre_scores_gemma":[0.9949643,0.0000317665,0.00022526617,0.0040748916,0.0003938824,0.000006317244,0.000013031094,0.000022670882,0.00026785364],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930024,0.000023013134,0.0001377348,0.00020862701,0.000153482,0.00017690785],"domain_scores_gemma":[0.99949616,0.000042599004,0.00004904571,0.00016669567,0.00002589043,0.00021959406],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000040453822,0.000105491745,0.00016498835,0.000017521246,0.000054375836,0.000011979517,0.00006781545,0.00005927386,0.0007641265],"category_scores_gemma":[0.000036051402,0.00008646371,0.00008100689,0.00009659731,0.00001560947,0.000045609515,0.000036180212,0.00012371404,0.00040296876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004644988,0.00005315797,0.0008715551,0.0000673034,0.000027570008,0.00005354018,0.0004353114,0.000005897328,0.98508495,0.000009831533,0.006217337,0.0071271053],"study_design_scores_gemma":[0.0010534949,0.00012271522,0.008412859,0.00019019788,0.000047786158,0.00000163172,0.00012962865,0.0013045166,0.97575676,0.00005236842,0.012807704,0.000120313205],"about_ca_topic_score_codex":0.0000039480497,"about_ca_topic_score_gemma":5.6666067e-8,"teacher_disagreement_score":0.009328157,"about_ca_system_score_codex":0.000013491241,"about_ca_system_score_gemma":0.000034403427,"threshold_uncertainty_score":0.8366649},"labels":[],"label_agreement":null},{"id":"W3035840506","doi":"10.1021/acsomega.0c01618","title":"Regulation of Autophagy Progress via Lysosomal Depletion by Fluvastatin Nanoparticle Treatment in Breast Cancer Cells","year":2020,"lang":"en","type":"article","venue":"ACS Omega","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Proinflammatory cytokine; PI3K/AKT/mTOR pathway; MAPK/ERK pathway; Protein kinase B; Cancer research; Cell biology; Biology; Viability assay; Cytokine; Protein kinase A; Kinase; Signal transduction; Cell; Inflammation; Immunology; Apoptosis; Biochemistry","score_opus":0.01148707979114794,"score_gpt":0.26853223294692397,"score_spread":0.25704515315577603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3035840506","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958474,0.00088512275,0.00003727707,0.0026538584,0.000042039806,0.00039041956,0.000059250076,0.00004463386,0.000039977993],"genre_scores_gemma":[0.99910396,0.00007697451,0.00011578682,0.0003934897,0.000075166994,0.00008186131,0.00004294079,0.00001875293,0.00009109245],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916655,0.00004076378,0.00024179074,0.00019841365,0.00017965234,0.00017281003],"domain_scores_gemma":[0.999591,0.000017472608,0.00008862538,0.00013671386,0.000043989687,0.00012220314],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003723004,0.00011557843,0.00022279,0.000037290156,0.000023263312,0.0000065267773,0.000043997974,0.0000512477,0.00013014411],"category_scores_gemma":[0.000003451173,0.000097965945,0.000049310784,0.00023132339,0.000050504594,0.0000834415,0.000011299248,0.000045036788,0.000018807401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006485895,0.0005015442,0.04122673,0.000058526206,0.0000662516,0.000022528251,0.0008508219,0.000052128227,0.93154037,0.00003194428,0.0006447803,0.024355803],"study_design_scores_gemma":[0.0025641469,0.00033671258,0.22038022,0.000037944723,0.00005657999,0.0000043664445,0.000046680387,0.0022896254,0.773837,0.000041271764,0.00032471755,0.000080753845],"about_ca_topic_score_codex":0.00017941328,"about_ca_topic_score_gemma":0.000009002973,"teacher_disagreement_score":0.17915349,"about_ca_system_score_codex":0.00007730521,"about_ca_system_score_gemma":0.00007364331,"threshold_uncertainty_score":0.39949355},"labels":[],"label_agreement":null},{"id":"W3036124869","doi":"10.1080/21505594.2020.1780088","title":"Autophagy and SARS-CoV-2 infection: A possible smart targeting of the autophagy pathway","year":2020,"lang":"en","type":"editorial","venue":"Virulence","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"National Institute of General Medical Sciences; NIH Office of the Director; National Institutes of Health","keywords":"Autophagy; Biology; Apoptosis; Coronavirus; Programmed cell death; Virology; Virus; Viral life cycle; Viral replication; Cell biology; Coronavirus disease 2019 (COVID-19); Medicine; Genetics; Disease","score_opus":0.014691028835287398,"score_gpt":0.28324042792163495,"score_spread":0.26854939908634756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3036124869","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2637511,0.010440493,0.00009559953,0.0004844416,0.720136,0.0012439223,0.0003946316,0.00035711544,0.0030967097],"genre_scores_gemma":[0.34437397,0.0030527643,0.00044424055,0.0016902004,0.6479933,0.00013842889,0.00019219737,0.00020932728,0.0019055534],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975522,0.00013320905,0.0005506789,0.0006047888,0.0008185937,0.00034049925],"domain_scores_gemma":[0.9983603,0.0002629656,0.00043148638,0.00058995467,0.0002284463,0.00012686735],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027337015,0.00040728835,0.00072928023,0.00009672247,0.0001824933,0.000042272237,0.0002893656,0.0005044291,0.00008069841],"category_scores_gemma":[0.0008597729,0.00029696192,0.00029474948,0.00041177776,0.00028393028,0.00011613869,0.00022552091,0.00097133726,0.00004548436],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034198022,0.00021939422,0.00088565843,0.0013816928,0.0003402564,0.00018313061,0.00060377014,0.0000014759839,0.091077246,0.00019126221,0.9010778,0.0036963231],"study_design_scores_gemma":[0.0013675307,0.0003528339,0.003948022,0.00081912987,0.0002514098,0.000018965333,0.000013088181,0.00015401383,0.27065217,0.00042992606,0.7216569,0.0003359664],"about_ca_topic_score_codex":0.0003213948,"about_ca_topic_score_gemma":0.000010958513,"teacher_disagreement_score":0.17957494,"about_ca_system_score_codex":0.000080561214,"about_ca_system_score_gemma":0.00096372823,"threshold_uncertainty_score":0.99994826},"labels":[],"label_agreement":null},{"id":"W3036498197","doi":"10.1016/j.jtherbio.2020.102643","title":"Regulation of autophagy following ex vivo heating in peripheral blood mononuclear cells from young adults","year":2020,"lang":"en","type":"article","venue":"Journal of Thermal Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; University of Ottawa","keywords":"Autophagy; Peripheral blood mononuclear cell; Inflammation; Ex vivo; Apoptosis; Heat shock protein; Heat stress; In vivo; Heat shock; Programmed cell death; Immunology; Cell biology; Medicine; Biology; In vitro; Biochemistry; Biotechnology","score_opus":0.010709198663163751,"score_gpt":0.25234747792109724,"score_spread":0.2416382792579335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3036498197","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976415,0.0013112691,0.00007248035,0.00032984745,0.00023346263,0.00010200617,0.000007634705,0.000010323111,0.00029147876],"genre_scores_gemma":[0.9977773,0.0000527762,0.0011867824,0.0004810991,0.00046202843,6.5831927e-7,0.0000045784686,0.000016656613,0.000018147803],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989169,0.00011557341,0.0005606662,0.00012850664,0.00012062039,0.0001576802],"domain_scores_gemma":[0.9993237,0.000058437596,0.00035346454,0.00009890399,0.00005493803,0.000110505796],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015141776,0.00011281782,0.00045245697,0.00006706982,0.000021046688,0.000004799467,0.00011498422,0.00012462884,0.0004432949],"category_scores_gemma":[0.000054255568,0.000089582645,0.00023907919,0.00010166732,0.00003565759,0.000087757864,0.000024926832,0.00022011028,0.000003945199],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015046888,0.00012574955,0.024416016,0.000018723107,0.00024326885,0.00013044532,0.0019747082,0.00024529372,0.9685636,0.000017496599,0.000021108384,0.002738857],"study_design_scores_gemma":[0.009519108,0.0024545917,0.28403547,0.00036388892,0.00027892765,0.000049986687,0.0006579096,0.0050356765,0.6969221,0.00035128577,0.0001487698,0.00018225858],"about_ca_topic_score_codex":0.000097616285,"about_ca_topic_score_gemma":0.000002679939,"teacher_disagreement_score":0.27164152,"about_ca_system_score_codex":0.000028012937,"about_ca_system_score_gemma":0.00006387089,"threshold_uncertainty_score":0.48537683},"labels":[],"label_agreement":null},{"id":"W3041009008","doi":"10.3389/fcell.2020.00591","title":"Organelle Cooperation in Stem Cell Fate: Lysosomes as Emerging Regulators of Cell Identity","year":2020,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Ottawa Hospital; Simon Fraser University","funders":"","keywords":"Cell fate determination; Stem cell; Biology; Cell biology; Reprogramming; Organelle; Cell; Mitochondrion; Lysosome; Signal transduction; Genetics; Transcription factor; Gene; Biochemistry","score_opus":0.01530990430600247,"score_gpt":0.27954459235663087,"score_spread":0.2642346880506284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3041009008","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03496113,0.9613523,0.00009698003,0.0000130509725,0.00055677973,0.0006926199,0.00002548873,0.000019945961,0.0022817142],"genre_scores_gemma":[0.013125533,0.9837343,0.0015264809,0.00009798319,0.00004357387,0.000033860306,0.0003416216,0.000036047444,0.0010606155],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981349,0.00015468668,0.0008014986,0.00051371637,0.00011398763,0.0002811965],"domain_scores_gemma":[0.99941003,0.00003949668,0.0002572279,0.00013979439,0.000025083806,0.0001283793],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016820605,0.00036462364,0.0015790462,0.0003815686,0.00004635187,0.000010243803,0.00016021833,0.00041743822,0.00013363696],"category_scores_gemma":[0.000007740624,0.00030878527,0.00013086849,0.0005147479,0.000116794756,0.00007931766,0.00012666007,0.00031272814,0.000040288676],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004340141,0.000973474,0.024744293,0.03684235,0.0004308229,0.000612574,0.004171655,0.0000014533781,0.0035668744,0.00013654496,0.007697216,0.92038876],"study_design_scores_gemma":[0.003630565,0.00038590023,0.00041415603,0.002865192,0.00039609033,0.000054564647,0.0025508055,0.000024448153,0.023037268,0.00029135548,0.9654271,0.0009225368],"about_ca_topic_score_codex":0.000031618347,"about_ca_topic_score_gemma":0.0000052586033,"teacher_disagreement_score":0.9577299,"about_ca_system_score_codex":0.00020757472,"about_ca_system_score_gemma":0.0005525962,"threshold_uncertainty_score":0.9999364},"labels":[],"label_agreement":null},{"id":"W3041921794","doi":"10.1093/database/baaa052","title":"Autophagy and Tumor Database: ATdb, a novel database connecting autophagy and tumor","year":2020,"lang":"en","type":"article","venue":"Database","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Fundamental Research Funds for the Central Universities; Zhejiang University; Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China","keywords":"Autophagy; Carcinogenesis; Biology; Database; Context (archaeology); microRNA; Computational biology; Bioinformatics; Cancer; Computer science; Cancer research; Gene; Genetics; Apoptosis","score_opus":0.035899491770201165,"score_gpt":0.29222322821871366,"score_spread":0.2563237364485125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3041921794","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9733106,0.006836503,0.004023331,0.0017962744,0.00024743166,0.0009947083,0.011945271,0.00045801385,0.00038787653],"genre_scores_gemma":[0.95633966,0.00049349567,0.014167353,0.020268975,0.0009889712,0.00008058918,0.0073437733,0.00016486719,0.00015231698],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99691707,0.000086324464,0.00059059035,0.0012294928,0.000497521,0.00067900127],"domain_scores_gemma":[0.9970586,0.00029822745,0.00023096352,0.0010776792,0.000096277894,0.0012382966],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004206109,0.0005396983,0.0007494765,0.00015688445,0.00032695627,0.00010525445,0.00026386863,0.00006866395,0.0009409346],"category_scores_gemma":[0.0009074366,0.0005026904,0.00009849488,0.00040359204,0.0002541157,0.0007517575,0.00066605816,0.00056951464,0.00012960933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003255374,0.0015776375,0.0039774952,0.0034799366,0.0007735343,0.0139510175,0.0018024239,0.0000056286103,0.9285197,0.008417358,0.025103372,0.009136499],"study_design_scores_gemma":[0.054126874,0.002550032,0.028606629,0.0029106853,0.0028835656,0.008590375,0.003923628,0.07335541,0.45853004,0.00017441643,0.3600496,0.004298762],"about_ca_topic_score_codex":0.00023626476,"about_ca_topic_score_gemma":0.000018281118,"teacher_disagreement_score":0.4699897,"about_ca_system_score_codex":0.000043693108,"about_ca_system_score_gemma":0.00025913367,"threshold_uncertainty_score":0.99997234},"labels":[],"label_agreement":null},{"id":"W3041988148","doi":"10.1101/2020.07.12.198424","title":"Friendly regulates membrane depolarization induced mitophagy in Arabidopsis","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Mitophagy; Cell biology; ATG8; Autophagy; Mitochondrion; Biology; Arabidopsis; Biogenesis; Biochemistry; Mutant; Gene; Apoptosis","score_opus":0.016634695481818722,"score_gpt":0.24132514210687783,"score_spread":0.2246904466250591,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3041988148","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939848,0.0021067453,0.00047934303,0.0008748065,0.0008166168,0.0011267763,0.000084815605,0.00049979484,0.000026274016],"genre_scores_gemma":[0.99521816,0.00042576093,0.0024191798,0.0008132837,0.0007449289,0.00018227208,0.000003008651,0.00018785767,0.000005579411],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968426,0.00015129797,0.00075145066,0.0011720463,0.00052763574,0.0005549748],"domain_scores_gemma":[0.99754053,0.00005678325,0.00038521457,0.0012461109,0.00028585052,0.00048550646],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026726426,0.00063657487,0.0009638103,0.00043052074,0.00009101096,0.00010915924,0.00038170067,0.00085542543,0.00013511494],"category_scores_gemma":[0.00026896838,0.00068279787,0.00024873696,0.000916657,0.000104522056,0.00015611286,0.00026600712,0.0011153026,0.00010341222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022181703,0.000311673,0.013266913,0.00072955166,0.00029828143,0.00050462695,0.000026438876,0.00002427984,0.98403364,0.00046752888,0.0001087711,0.0000064955047],"study_design_scores_gemma":[0.001492283,0.000115686744,0.28458822,0.0005328352,0.00019927238,5.20964e-8,0.0000034072398,0.00052013993,0.7115359,0.000010632953,0.00044773772,0.00055388117],"about_ca_topic_score_codex":0.00007946967,"about_ca_topic_score_gemma":0.0000024228102,"teacher_disagreement_score":0.27249777,"about_ca_system_score_codex":0.00029789392,"about_ca_system_score_gemma":0.0009232782,"threshold_uncertainty_score":0.9995623},"labels":[],"label_agreement":null},{"id":"W3041995657","doi":"10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2377","title":"The Influence of Autophagy Inhibition on Sepsis-Induced Skeletal Muscle Wasting, Metabolic Derangements and Mortality","year":2020,"lang":"en","type":"article","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal; McGill University","funders":"","keywords":"Wasting; Autophagy; Sepsis; Skeletal muscle; Medicine; Intensive care medicine; Internal medicine; Chemistry; Biochemistry","score_opus":0.0294221555979862,"score_gpt":0.30393561495124327,"score_spread":0.27451345935325705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3041995657","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99721295,0.00042501246,0.000018053792,0.0008168958,0.000028836945,0.00028738627,0.0000052857695,0.000055086723,0.0011505096],"genre_scores_gemma":[0.9965075,0.00019443754,0.00004348732,0.0031078912,0.000072088034,0.000015330304,0.000005665879,0.000010556313,0.000042991625],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99915874,0.000041015715,0.00021959787,0.00018718108,0.00024959474,0.0001438937],"domain_scores_gemma":[0.99948716,0.000059430044,0.000081360486,0.00018067562,0.000056138557,0.0001352346],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011064143,0.00010972114,0.00018768858,0.000021548567,0.00009538628,0.000012828869,0.000047595473,0.00004052167,0.00007871608],"category_scores_gemma":[0.00012051635,0.000070787624,0.00006354866,0.00012585132,0.000066427834,0.00007133861,0.00003320538,0.000097817705,0.000014636899],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037017828,0.0007270007,0.037530717,0.00051358424,0.0010336782,0.00015264763,0.0022018373,0.000120715646,0.8800829,0.012957721,0.0007301217,0.06357888],"study_design_scores_gemma":[0.0012001912,0.0002328389,0.8881631,0.000045364075,0.00010049618,0.0000014924957,0.0000853048,0.0003228284,0.10891612,0.00021641258,0.0006420362,0.00007380168],"about_ca_topic_score_codex":0.000031029245,"about_ca_topic_score_gemma":0.000004528637,"teacher_disagreement_score":0.8506324,"about_ca_system_score_codex":0.000007058674,"about_ca_system_score_gemma":0.000043172677,"threshold_uncertainty_score":0.28866357},"labels":[],"label_agreement":null},{"id":"W3042443953","doi":"10.1126/science.abb7041","title":"Nailing a Fe-rocious form of cancer","year":2020,"lang":"en","type":"letter","venue":"Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; McGill University; McGill University Health Centre","funders":"","keywords":"Cancer; Cancer cell; Brain cancer; Chemistry; Cancer research; Medicine; Internal medicine","score_opus":0.024372200513286042,"score_gpt":0.3329280079865374,"score_spread":0.30855580747325134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3042443953","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.117340356,0.00695844,0.00007248189,0.8700931,0.0010572302,0.00054790505,0.00007738268,0.00011160907,0.0037414988],"genre_scores_gemma":[0.11134621,0.0002777231,0.0002273983,0.88388795,0.0018336873,0.000023019493,0.0000126753885,0.000021753018,0.0023695927],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986012,0.0000058388723,0.00016460185,0.00032035398,0.00063753064,0.0002704703],"domain_scores_gemma":[0.9993743,0.000022389606,0.00011644476,0.00027984637,0.00011381321,0.00009322365],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000081460144,0.00012309746,0.00027306494,0.00010049276,0.00008212026,0.000012131113,0.00031385059,0.00011065145,0.00025053998],"category_scores_gemma":[0.000055039265,0.00009604527,0.00009895513,0.00043305545,0.0005342387,0.0000652866,0.000054699398,0.00048989576,0.000034524077],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000093877155,0.00005518804,0.001482537,0.0013277127,0.0001475213,0.001636672,0.0026381002,0.0000019112713,0.037271287,0.00004756957,0.92989784,0.025399791],"study_design_scores_gemma":[0.0006232723,0.00019875089,0.0016276449,0.00050480675,0.00014214404,0.000020991152,0.000051473464,0.00027713337,0.037450977,0.0016818682,0.9571677,0.00025326113],"about_ca_topic_score_codex":0.000047768324,"about_ca_topic_score_gemma":0.000001808744,"teacher_disagreement_score":0.027269844,"about_ca_system_score_codex":0.00008671108,"about_ca_system_score_gemma":0.0010380023,"threshold_uncertainty_score":0.39166123},"labels":[],"label_agreement":null},{"id":"W3042911950","doi":"10.1038/s42003-020-1090-2","title":"Ribosome profiling reveals a functional role for autophagy in mRNA translational control","year":2020,"lang":"en","type":"article","venue":"Communications Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; Cancer Research Society; National Cancer Institute; National Institutes of Health; National Science Foundation; U.S. Department of Health and Human Services; Government of Canada; U.S. Department of Defense","keywords":"Autophagy; Ribosome profiling; Cell biology; Biology; Protein biosynthesis; Translational regulation; DNA repair; Translation (biology); DNA damage; Ribosome; BAG3; Protein degradation; Messenger RNA; DNA; Genetics; RNA; Gene; Apoptosis","score_opus":0.06611091558144015,"score_gpt":0.33933815299175174,"score_spread":0.2732272374103116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3042911950","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7662086,0.03290215,0.05136357,0.1348763,0.00026495484,0.0051226667,0.0009460948,0.00043542514,0.007880232],"genre_scores_gemma":[0.98832434,0.00012407431,0.0059687495,0.004231563,0.0001294262,0.00038076585,0.0007806163,0.000012491754,0.00004795689],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"observational","domain_scores_codex":[0.9992263,0.00010888855,0.00029047177,0.00017244581,0.000047285932,0.00015462791],"domain_scores_gemma":[0.9989819,0.0003443027,0.000064291926,0.0004329752,0.000088371606,0.000088177265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014826517,0.0000903296,0.00023252136,0.00006769338,0.00010036636,0.0000046362516,0.00022194888,0.00010492804,0.00012823073],"category_scores_gemma":[0.00013195476,0.00008446823,0.000099777375,0.00015536963,0.00010139086,0.000040533276,0.000028627119,0.00016985108,0.000028550488],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024734135,0.0010206938,0.17343913,0.000116487245,0.000494254,0.0000039561564,0.0010978369,0.00015845094,0.37712958,0.42841804,0.00076267053,0.014885481],"study_design_scores_gemma":[0.03113598,0.0015299533,0.602689,0.0001200847,0.00037170624,0.000048124886,0.00045373355,0.12663208,0.011848206,0.12789878,0.09655062,0.0007217171],"about_ca_topic_score_codex":0.0000039586525,"about_ca_topic_score_gemma":0.0000041869953,"teacher_disagreement_score":0.42924988,"about_ca_system_score_codex":0.000023187213,"about_ca_system_score_gemma":0.00014251364,"threshold_uncertainty_score":0.34445143},"labels":[],"label_agreement":null},{"id":"W3043063836","doi":"10.1016/j.joca.2020.07.001","title":"TAT-Beclin-1 induces severe synovial hyperplasia and does not protect from injury-induced osteoarthritis in mice","year":2020,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Health Research","keywords":"Osteoarthritis; Cartilage; Fibrosis; Hyperplasia; Autophagy; Synovitis; Histopathology; Chemistry; Pathology; Medicine; Endocrinology; Internal medicine; Apoptosis; Arthritis; Anatomy","score_opus":0.012567624285240485,"score_gpt":0.2415683276053061,"score_spread":0.2290007033200656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3043063836","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914112,0.004098865,0.0000014289807,0.0021179316,0.00017251798,0.00093615754,0.00040308008,0.000100748824,0.0007580759],"genre_scores_gemma":[0.9956446,0.0005564706,0.00012744653,0.0029054806,0.00045649958,0.000116159244,0.000052483192,0.000050608698,0.00009022216],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980204,0.00012352403,0.00045078027,0.0006892342,0.00031044835,0.00040560158],"domain_scores_gemma":[0.99908555,0.00008185515,0.00010313903,0.00022666306,0.000051624986,0.00045115245],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013083806,0.00033932613,0.0006361953,0.000082751074,0.00012311625,0.0001052435,0.00009892065,0.0002521215,0.00024162306],"category_scores_gemma":[0.00010019089,0.00029397354,0.0000980809,0.00019676168,0.00014505198,0.00025499085,0.00010212658,0.00042025847,0.00003556933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012511602,0.00006567862,0.004365558,0.0000763436,0.000013210292,0.00074453274,0.0017801824,8.8909786e-8,0.8540368,0.00004797896,0.00006352641,0.13755493],"study_design_scores_gemma":[0.01136224,0.0036547557,0.007813587,0.00062070956,0.000117962816,0.00020868535,0.0019522641,0.000009442136,0.9694762,0.00030293418,0.0038238245,0.0006573579],"about_ca_topic_score_codex":0.00010343644,"about_ca_topic_score_gemma":0.00028163916,"teacher_disagreement_score":0.13689756,"about_ca_system_score_codex":0.000022166909,"about_ca_system_score_gemma":0.00009801314,"threshold_uncertainty_score":0.99995124},"labels":[],"label_agreement":null},{"id":"W3044249165","doi":"10.1007/s10549-020-05795-z","title":"Differential expression and prognostic relevance of autophagy-related markers ATG4B, GABARAP, and LC3B in breast cancer","year":2020,"lang":"en","type":"article","venue":"Breast Cancer Research and Treatment","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; University of British Columbia; University of British Columbia Hospital; Canada's Michael Smith Genome Sciences Centre","funders":"Canadian Institutes of Health Research","keywords":"Breast cancer; Tissue microarray; Oncology; Immunohistochemistry; Internal medicine; Clinical significance; Autophagy; Cancer; Proportional hazards model; Medicine; Biology; Biomarker; Genetics; Apoptosis","score_opus":0.030517490483007243,"score_gpt":0.3410157086576971,"score_spread":0.31049821817468987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3044249165","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9817226,0.012860689,0.0000020516798,0.004116434,0.000029177423,0.0008307911,0.0003388521,0.000025310557,0.000074112104],"genre_scores_gemma":[0.9794145,0.019909583,0.00002562609,0.00006184992,0.00008494602,0.00029740564,0.000018588662,0.000025173304,0.00016231475],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984434,0.000095476964,0.0002420342,0.00047438304,0.0003546736,0.0003900055],"domain_scores_gemma":[0.99912447,0.00010504738,0.000056393576,0.00015288824,0.00009614377,0.0004650694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000071950206,0.00021048138,0.00038958006,0.00011839795,0.00009725415,0.000024603667,0.000050416103,0.000088509136,0.00043133437],"category_scores_gemma":[0.000014023032,0.00015056005,0.000042188818,0.00025186047,0.0003212437,0.00008820767,0.00007354856,0.00019483035,0.0000018276044],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.014562747,0.0011050948,0.697817,0.0006232727,0.0005814923,0.00043171475,0.0015819191,0.0000054356824,0.04345562,0.000097843316,0.00026586908,0.23947197],"study_design_scores_gemma":[0.00819656,0.00079286454,0.98206145,0.0008112366,0.00008819479,0.00010817433,0.00015005209,0.00068860105,0.0067427857,0.00012776005,0.000096685944,0.0001356453],"about_ca_topic_score_codex":0.0014303112,"about_ca_topic_score_gemma":0.00006857244,"teacher_disagreement_score":0.28424442,"about_ca_system_score_codex":0.00013665068,"about_ca_system_score_gemma":0.00022700257,"threshold_uncertainty_score":0.6139661},"labels":[],"label_agreement":null},{"id":"W3045653589","doi":"","title":"Modulation of autophagic activity by chemotactic GPCRs controls the invasive potential of glioblastoma cells","year":2016,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Autophagy; Chemotaxis; Glioblastoma; Modulation (music); G protein-coupled receptor; Cell biology; Chemistry; Cancer research; Biology; Signal transduction; Receptor; Biochemistry; Apoptosis; Physics","score_opus":0.007828637615008701,"score_gpt":0.22902864748260615,"score_spread":0.22120000986759744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3045653589","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96108127,0.00091989624,0.02871646,0.004244736,0.00019161396,0.0009480358,0.00021683257,0.0000737736,0.0036073586],"genre_scores_gemma":[0.9963197,0.00052229664,0.0005859455,0.00007723621,0.000032156295,0.000048389935,0.00010627145,0.000040262275,0.002267719],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99593014,0.0022198746,0.00055208063,0.0004890293,0.00055706664,0.00025182572],"domain_scores_gemma":[0.9939556,0.0012325576,0.0011398013,0.0018646853,0.0016645925,0.00014273821],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018103138,0.00029857355,0.0006095374,0.00013195402,0.00013121874,0.000044558485,0.0006163509,0.0002944679,0.00023575721],"category_scores_gemma":[0.0006687811,0.00022305801,0.00038480337,0.00020185493,0.0004403818,0.00010073638,0.00042482364,0.0004216119,0.000012617215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042808833,0.0011136938,0.00043429757,0.00039271158,0.00044317145,0.000005588603,0.0015999553,0.000047230555,0.97419906,0.002194163,0.0006021218,0.018539907],"study_design_scores_gemma":[0.001738853,0.00000296246,0.0140191335,0.0014001797,0.00022519719,0.0000069124467,0.000033779765,0.00548189,0.9742211,0.0024020767,0.00027469252,0.0001931905],"about_ca_topic_score_codex":0.00029297854,"about_ca_topic_score_gemma":0.000041634787,"teacher_disagreement_score":0.03523843,"about_ca_system_score_codex":0.00010207921,"about_ca_system_score_gemma":0.00047356973,"threshold_uncertainty_score":0.9096042},"labels":[],"label_agreement":null},{"id":"W3045797839","doi":"10.1007/s11010-020-03848-x","title":"Dynamic regulation of histone H3 lysine (K) acetylation and deacetylation during prolonged oxygen deprivation in a champion anaerobe","year":2020,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Acetylation; Histone Acetyltransferases; Histone; Histone H3; Chromatin; Epigenetics; Biology; Biochemistry; Lysine; Cell biology; Gene; Amino acid","score_opus":0.0048290405115122585,"score_gpt":0.23512811238102602,"score_spread":0.23029907186951376,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3045797839","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932853,0.002470537,0.003233402,0.00066916953,0.000007186271,0.0002541028,0.0000026436953,0.00002441799,0.00005323727],"genre_scores_gemma":[0.99910706,0.00004422277,0.00044238273,0.00008565607,0.00001834744,0.000009574223,0.00025463416,0.000015523454,0.000022575186],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992366,0.000023720888,0.00022261581,0.0002590641,0.00014602249,0.000111987465],"domain_scores_gemma":[0.9996191,0.0000049532646,0.00010424763,0.0001379479,0.00004125052,0.00009248171],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000750687,0.00011472701,0.00017553086,0.000049697614,0.00003092057,0.000006802123,0.00002588287,0.000120640536,0.00001199837],"category_scores_gemma":[0.000039389568,0.0001238746,0.000038376966,0.00017186886,0.0000436779,0.000045664103,0.00002406913,0.00008573325,4.7588026e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027030543,0.000044288372,0.0041334974,0.00033624007,0.000026922835,0.000014513815,0.00020991279,0.00003980575,0.9939172,0.000027141732,0.000001026318,0.0009791262],"study_design_scores_gemma":[0.001567421,0.000057080153,0.06189963,0.00006910416,0.00005019046,0.0000081414,0.000051000214,0.007129323,0.9289685,0.000098291006,0.000004218322,0.0000970874],"about_ca_topic_score_codex":0.000006781621,"about_ca_topic_score_gemma":5.8834326e-7,"teacher_disagreement_score":0.0649487,"about_ca_system_score_codex":0.00004807249,"about_ca_system_score_gemma":0.000026943471,"threshold_uncertainty_score":0.505146},"labels":[],"label_agreement":null},{"id":"W3046040523","doi":"10.1152/ajpcell.00241.2020","title":"More than just a garbage can: emerging roles of the lysosome as an anabolic organelle in skeletal muscle","year":2020,"lang":"en","type":"review","venue":"American Journal of Physiology-Cell Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; Government of Canada","keywords":"Lysosome; TFEB; mTORC1; Autophagy; Cell biology; Anabolism; Biology; Skeletal muscle; Catabolism; Biogenesis; Organelle biogenesis; Signal transduction; Biochemistry; Endocrinology; PI3K/AKT/mTOR pathway; Metabolism","score_opus":0.014967438369770183,"score_gpt":0.31340588056483665,"score_spread":0.2984384421950665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3046040523","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.49375916,0.5052283,5.363584e-7,0.00026013824,0.00023801078,0.00038935765,0.000042865486,0.000015810683,0.0000658177],"genre_scores_gemma":[0.4116207,0.5868243,0.000036557998,0.0006658216,0.0006793989,0.00001438182,0.000044791777,0.00008348861,0.000030586056],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99606025,0.0010226672,0.0014006419,0.00060687953,0.00031032678,0.0005992086],"domain_scores_gemma":[0.99573296,0.00020873918,0.0026923108,0.0008528693,0.00017094129,0.00034215415],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019127692,0.0006785556,0.0044994797,0.00037455148,0.00008662587,0.0000058405876,0.0010262423,0.00026804514,0.00021926574],"category_scores_gemma":[0.00008379439,0.00043285437,0.0013878124,0.0010886071,0.0012396118,0.00008063552,0.00022378842,0.0014315258,0.000021784994],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00072400126,0.002619811,0.00006308431,0.007169235,0.0023730001,0.0004327909,0.0048146346,0.00014041418,0.3206079,0.00012264757,0.00057097187,0.66036147],"study_design_scores_gemma":[0.009109125,0.019104611,0.047888886,0.013938652,0.008448349,0.0015504855,0.014530745,0.00013868569,0.00473082,0.0023442898,0.87529206,0.0029233086],"about_ca_topic_score_codex":0.00015146856,"about_ca_topic_score_gemma":0.000011525915,"teacher_disagreement_score":0.87472105,"about_ca_system_score_codex":0.00012463277,"about_ca_system_score_gemma":0.0013020014,"threshold_uncertainty_score":0.9998123},"labels":[],"label_agreement":null},{"id":"W3048659704","doi":"10.1101/2020.08.13.244640","title":"Foam cell induction activates AMPK but uncouples its regulation of autophagy and lysosomal homeostasis","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"National Health and Medical Research Council; Medical Research Council; Canadian Institutes of Health Research; Ontario Ministry of Research, Innovation and Science; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"AMPK; Cell biology; Autophagy; Foam cell; AMP-activated protein kinase; CD36; Signal transduction; Protein kinase A; Chemistry; Transcription factor; Lipid metabolism; Cell signaling; Regulator; Phosphorylation; Macrophage; Biology; Biochemistry; Receptor; Apoptosis","score_opus":0.020044663983346183,"score_gpt":0.23507012342706007,"score_spread":0.2150254594437139,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3048659704","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921748,0.0053267507,0.00024200235,0.00038278353,0.0005058927,0.0008392892,0.00021643683,0.0002985264,0.000013507991],"genre_scores_gemma":[0.9963695,0.001360564,0.0013118675,0.00015270551,0.0005907896,0.00008176218,0.0000027585988,0.00011865492,0.000011435117],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99769545,0.000090895424,0.000570133,0.00084863947,0.00045861813,0.0003362977],"domain_scores_gemma":[0.9978039,0.00006194951,0.0005883595,0.0007426278,0.00044952793,0.00035360135],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002003407,0.0005001967,0.00080033916,0.00028784762,0.00010584846,0.000062829626,0.00019001319,0.00058830646,0.000105683335],"category_scores_gemma":[0.00014840906,0.0005137626,0.00018231104,0.00042365285,0.00013866942,0.00018680177,0.0002337916,0.0005790754,0.000019951136],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000272314,0.00022561406,0.0025010568,0.0015005528,0.0003039969,0.000036835958,0.000028460194,0.000021693228,0.9947115,0.00026871415,0.00010717723,0.0000220577],"study_design_scores_gemma":[0.0008904786,0.00013280733,0.2734282,0.0002954369,0.00031914958,4.2531017e-8,0.000008743517,0.0003887681,0.7238925,0.0000115367075,0.00031761272,0.00031469422],"about_ca_topic_score_codex":0.000034470577,"about_ca_topic_score_gemma":3.52964e-7,"teacher_disagreement_score":0.27092713,"about_ca_system_score_codex":0.00016105176,"about_ca_system_score_gemma":0.0005957015,"threshold_uncertainty_score":0.9997314},"labels":[],"label_agreement":null},{"id":"W3048958888","doi":"10.7150/jca.46697","title":"Moxidectin induces Cytostatic Autophagic Cell Death of Glioma Cells through inhibiting the AKT/mTOR Signalling Pathway","year":2020,"lang":"en","type":"article","venue":"Journal of Cancer","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Natural Science Foundation of China; University of Ottawa","keywords":"Autophagy; PI3K/AKT/mTOR pathway; Glioma; Apoptosis; TUNEL assay; Protein kinase B; Cancer research; Viability assay; Chemistry; Cell biology; Biology; Biochemistry","score_opus":0.0370391582514437,"score_gpt":0.3046050307144856,"score_spread":0.26756587246304187,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3048958888","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9861492,0.010690706,0.00046855764,0.0016300154,0.0002187177,0.0001735339,0.000010900126,0.000013330772,0.00064503175],"genre_scores_gemma":[0.99574846,0.00042500423,0.00071241264,0.0021771865,0.00085019117,0.0000044713147,6.1243134e-7,0.000028935672,0.00005270305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984429,0.00007719658,0.00064443686,0.00012869867,0.00050151016,0.00020527253],"domain_scores_gemma":[0.99852973,0.00018044404,0.00078607176,0.00010489193,0.00023820775,0.00016065336],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024494485,0.00015787748,0.00043429903,0.000054865155,0.00007211157,0.000020930893,0.00017015352,0.00006509322,0.00035278313],"category_scores_gemma":[0.000059590096,0.00009760937,0.00024378808,0.00025229348,0.000052932777,0.00015690662,0.000025463856,0.00039648477,0.000006546949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004191493,0.00011045201,0.00063755346,0.00020114676,0.00024810748,0.00034478994,0.004442968,0.0006021745,0.99091285,0.00007326915,0.00030428206,0.0017032612],"study_design_scores_gemma":[0.0017035301,0.00054044405,0.00084646844,0.00038697757,0.00026183005,0.000039774553,0.0010701801,0.00026169725,0.9935879,0.0004651869,0.0007376931,0.000098287455],"about_ca_topic_score_codex":0.000034364955,"about_ca_topic_score_gemma":9.472536e-7,"teacher_disagreement_score":0.010265701,"about_ca_system_score_codex":0.00006547578,"about_ca_system_score_gemma":0.00048751975,"threshold_uncertainty_score":0.39803946},"labels":[],"label_agreement":null},{"id":"W3075109078","doi":"10.2144/btn-2020-0071","title":"An Optimized Procedure For Quantitative Analysis of Mitophagy With the Mtkeima System Using Flow Cytometry","year":2020,"lang":"en","type":"article","venue":"BioTechniques","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Flow cytometry; Biology; Quantitative analysis (chemistry); Cytometry; Computational biology; Cell biology; Computer science; Autophagy; Chemistry; Molecular biology; Genetics; Apoptosis; Chromatography","score_opus":0.043018013272157915,"score_gpt":0.3494206290553855,"score_spread":0.3064026157832276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3075109078","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5007985,0.0009551749,0.49588948,0.00071224966,0.000011356354,0.0011749319,0.00011375041,0.00029139293,0.000053143027],"genre_scores_gemma":[0.8361083,0.000020360505,0.1632867,0.0004055043,0.000056736633,0.000057339126,0.000037841757,0.000022334796,0.000004874288],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917346,0.000054139833,0.00020659935,0.00024113571,0.000189864,0.00013478643],"domain_scores_gemma":[0.9992253,0.000066551744,0.00015783182,0.00026779732,0.00018347151,0.000099041004],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015501493,0.00014259735,0.00048727062,0.00017921794,0.000070361704,0.000014664292,0.00013324285,0.000110643916,0.000014386097],"category_scores_gemma":[0.000034965524,0.00008279392,0.0001964595,0.0010191504,0.00009108143,0.0000673328,0.000012111399,0.00008959594,3.7323588e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.014660855,0.0006294396,0.0023081175,0.0022075663,0.011356264,0.000082449544,0.0048439964,0.002411479,0.9541997,0.00435702,0.0007958198,0.0021473474],"study_design_scores_gemma":[0.0010996519,0.0018759504,0.001226518,0.0001710003,0.0032297259,0.0000071501036,0.0016814776,0.31869328,0.67171896,0.000009899942,0.000120566154,0.00016584642],"about_ca_topic_score_codex":0.000021144737,"about_ca_topic_score_gemma":0.0000012264944,"teacher_disagreement_score":0.3353098,"about_ca_system_score_codex":0.000036470785,"about_ca_system_score_gemma":0.000104517676,"threshold_uncertainty_score":0.33762383},"labels":[],"label_agreement":null},{"id":"W3079382483","doi":"10.1002/ana.25879","title":"Loss‐of‐Function Variants in <scp>HOPS</scp> Complex Genes <scp><i>VPS16</i></scp> and <scp><i>VPS41</i></scp> Cause Early Onset Dystonia Associated with Lysosomal Abnormalities","year":2020,"lang":"en","type":"article","venue":"Annals of Neurology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":110,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; Universität Innsbruck; Ministry of Education – Kingdom of Saudi Arabi; Medizinische Universität Innsbruck; Vedecká Grantová Agentúra MŠVVaŠ SR a SAV; Medical Research Council Canada; Technische Universität München; Agentúra na Podporu Výskumu a Vývoja; Helmholtz Zentrum München; National Institute for Health and Care Research; Fonds Psychische Gezondheid; Dystonia Medical Research Foundation; ZonMw; Department of Health and Aged Care, Australian Government; Rosetrees Trust; European Commission; National Health and Medical Research Council; Academy of Medical Sciences; Cancer Research UK; Else Kröner-Fresenius-Stiftung; European Social Fund; Univerzita Karlova v Praze; Wellcome Trust","keywords":"Dystonia; Loss function; Phenotype; Exome sequencing; Gene; Compound heterozygosity; Medicine; Biology; Genetics; Neuroscience","score_opus":0.04941958616020292,"score_gpt":0.2791824880370186,"score_spread":0.2297629018768157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3079382483","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99389786,0.0021700198,0.000037751626,0.0015198918,0.00019377761,0.0006310897,0.00031627505,0.0001512332,0.0010821051],"genre_scores_gemma":[0.9861161,0.0011465835,0.000041995143,0.01183722,0.00020947309,0.00004523843,0.00020161706,0.0001011022,0.00030066623],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9960182,0.00060624856,0.0009683426,0.0008259289,0.00060838624,0.0009729187],"domain_scores_gemma":[0.9957384,0.0020515525,0.0007183903,0.0005287644,0.00045187547,0.0005110086],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041983154,0.00057815405,0.0013365198,0.00038062708,0.00014281971,0.000034957156,0.00032650895,0.00048304928,0.000030481497],"category_scores_gemma":[0.0014228253,0.0005376521,0.00021255201,0.00074181176,0.00073867745,0.00031491456,0.00016095617,0.0006454547,0.000026488486],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00092392095,0.0014013981,0.9492283,0.00047885688,0.0019556885,0.0029456709,0.005599714,0.00020892902,0.021954179,0.0009910832,0.0138495425,0.00046273714],"study_design_scores_gemma":[0.004568787,0.0065699597,0.9703812,0.000085972766,0.00036140453,0.00028497292,0.00039441485,0.00039192452,0.010702316,0.0009690877,0.005211807,0.000078170735],"about_ca_topic_score_codex":0.00026421703,"about_ca_topic_score_gemma":0.00013161536,"teacher_disagreement_score":0.021152902,"about_ca_system_score_codex":0.0000144730475,"about_ca_system_score_gemma":0.00026714304,"threshold_uncertainty_score":0.9997075},"labels":[],"label_agreement":null},{"id":"W3080290327","doi":"10.3390/cancers12092371","title":"Dual Inhibition of Autophagy and PI3K/AKT/MTOR Pathway as a Therapeutic Strategy in Head and Neck Squamous Cell Carcinoma","year":2020,"lang":"en","type":"article","venue":"Cancers","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Université de Montréal","keywords":"PI3K/AKT/mTOR pathway; Autophagy; Head and neck squamous-cell carcinoma; Cancer research; Protein kinase B; Biology; Chemistry; Medicine; Cell biology; Cancer; Signal transduction; Apoptosis; Head and neck cancer; Internal medicine; Biochemistry","score_opus":0.02303442218408386,"score_gpt":0.26818967363794405,"score_spread":0.2451552514538602,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3080290327","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989113,0.00881453,0.0000058968835,0.00028844154,0.000036185727,0.00028872187,0.000021120646,0.00002379759,0.0014083401],"genre_scores_gemma":[0.9980369,0.00013977112,0.0000140387665,0.0015848038,0.000094756084,0.000018189141,0.0000121906305,0.000018476147,0.00008087408],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99926317,0.000030440082,0.00018640983,0.00023122625,0.0001224133,0.00016632622],"domain_scores_gemma":[0.99960685,0.000025924375,0.00006037917,0.00010210079,0.000026538604,0.0001781819],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000402333,0.0001279263,0.00024884287,0.000048654692,0.0000248101,0.000008623054,0.00002314806,0.00007453072,0.000116411145],"category_scores_gemma":[0.000008941818,0.000117247844,0.000035247387,0.00013388666,0.000098220466,0.000060117145,0.0000143776515,0.00012352786,0.000003922834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006917501,0.00041582357,0.070168726,0.0027767573,0.00015514262,0.002170717,0.020937385,0.0004318358,0.83662957,0.002754421,0.0008420853,0.055800024],"study_design_scores_gemma":[0.021528244,0.007069627,0.36410895,0.00021090385,0.00017849533,0.00007438303,0.0033149743,0.0040187687,0.5962941,0.0012240204,0.0014466711,0.0005308393],"about_ca_topic_score_codex":0.00038197613,"about_ca_topic_score_gemma":0.000025440355,"teacher_disagreement_score":0.29394022,"about_ca_system_score_codex":0.00011777707,"about_ca_system_score_gemma":0.00047179,"threshold_uncertainty_score":0.47812286},"labels":[],"label_agreement":null},{"id":"W3081645843","doi":"10.1158/1538-7445.am2020-3401","title":"Abstract 3401: Targeting lysosomal homeostasis in ovarian cancer through drug repurposing","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"","keywords":"Autophagy; Drug repositioning; Ovarian cancer; Pharmacology; Biology; Drug; PI3K/AKT/mTOR pathway; Cancer; Cancer research; Cell biology; Signal transduction; Apoptosis; Biochemistry; Genetics","score_opus":0.10644783419795278,"score_gpt":0.42873847055609354,"score_spread":0.32229063635814076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3081645843","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94806343,0.030221757,0.000014275507,0.01751921,0.00014903847,0.00062199304,0.000041867548,0.00006597984,0.0033024664],"genre_scores_gemma":[0.98995036,0.006149542,0.00018317,0.0020327095,0.0011038476,0.00024561275,0.000020270427,0.000056081986,0.0002584313],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99751717,0.00012309579,0.0003408594,0.0005323299,0.0007612163,0.0007253213],"domain_scores_gemma":[0.9990021,0.00012276703,0.00006022905,0.000285693,0.00020030627,0.0003288816],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005250243,0.00016892733,0.00034327037,0.00012363757,0.0001863952,0.000055600434,0.00022634746,0.00009733562,0.003219048],"category_scores_gemma":[0.00019231132,0.00015320437,0.00010145352,0.0009316517,0.00015401408,0.00021021292,0.000099853554,0.0008941486,0.000076647135],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006272232,0.0007408216,0.10276567,0.0023326029,0.0007468876,0.0040077846,0.035422098,0.00051762804,0.6502449,0.0011131819,0.082403705,0.11343251],"study_design_scores_gemma":[0.009840273,0.0003541002,0.17921524,0.0023271625,0.00010573721,0.000012332324,0.0054763933,0.0005687245,0.6560482,0.0015328716,0.14361233,0.00090669293],"about_ca_topic_score_codex":0.0043978654,"about_ca_topic_score_gemma":0.00011681507,"teacher_disagreement_score":0.11252582,"about_ca_system_score_codex":0.00040131315,"about_ca_system_score_gemma":0.0008540508,"threshold_uncertainty_score":0.99769217},"labels":[],"label_agreement":null},{"id":"W3083569853","doi":"10.1158/1538-7445.am2020-276","title":"Abstract 276: Mir-139 regulates autophagy in prostate cancer cells through Beclin-1 and mTOR signaling proteins","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"LNCaP; DU145; Prostate cancer; Cancer research; Autophagy; PI3K/AKT/mTOR pathway; Downregulation and upregulation; microRNA; Cancer cell; Cancer; Biology; Medicine; Cell biology; Signal transduction; Internal medicine; Apoptosis; Biochemistry; Gene","score_opus":0.0925193703593268,"score_gpt":0.41202558521414895,"score_spread":0.31950621485482217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3083569853","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97126746,0.018034484,0.0000037432555,0.008518724,0.00008468406,0.0016045707,0.0000739882,0.00006600219,0.00034631434],"genre_scores_gemma":[0.9923476,0.0043075294,0.00019201796,0.0010658882,0.000543278,0.0006516889,0.000012227485,0.000058161422,0.0008216102],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99770415,0.00009880554,0.0003362065,0.00057465484,0.0006271861,0.00065900903],"domain_scores_gemma":[0.9989664,0.000117315925,0.00006580878,0.00029528138,0.00020034278,0.00035483626],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00041004305,0.00020105613,0.0003771274,0.00010697418,0.00014004803,0.00006015376,0.00020442877,0.00011186217,0.0014873147],"category_scores_gemma":[0.00009447423,0.00017059267,0.00006777625,0.0005332888,0.00026037148,0.00017746544,0.00012480163,0.00071817904,0.000047119996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015766176,0.00015955922,0.003632491,0.0009468988,0.000126075,0.0005054268,0.0051468625,0.000106380045,0.9767048,0.00006779759,0.003319583,0.007707515],"study_design_scores_gemma":[0.0027216654,0.00031429404,0.017732808,0.0006604062,0.000024265259,0.0000027030358,0.00045868923,0.00029034715,0.9666583,0.0007458933,0.010168945,0.00022170898],"about_ca_topic_score_codex":0.0021303555,"about_ca_topic_score_gemma":0.00009885737,"teacher_disagreement_score":0.021080108,"about_ca_system_score_codex":0.00021852838,"about_ca_system_score_gemma":0.00078263244,"threshold_uncertainty_score":0.9994255},"labels":[],"label_agreement":null},{"id":"W3083912737","doi":"10.1007/s11626-020-00490-1","title":"Pharmacological and nutritional modulation of autophagy in a rainbow trout (Oncorhynchus mykiss) gill cell line, RTgill-W1","year":2020,"lang":"en","type":"article","venue":"In Vitro Cellular & Developmental Biology - Animal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Huntsman Marine Science Centre; Mowi (Canada); University of Guelph","funders":"Ontario Veterinary College, University of Guelph; Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Agriculture, Food and Rural Affairs","keywords":"Autophagy; BECN1; Rainbow trout; Western blot; Biology; Cell biology; Downregulation and upregulation; Immunoglobulin light chain; Autophagy-related protein 13; Immunofluorescence; Microtubule; Blot; Molecular biology; Gene; Signal transduction; Biochemistry; Immunology; Antibody; Fishery","score_opus":0.025153848600510585,"score_gpt":0.27677119391872834,"score_spread":0.2516173453182178,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3083912737","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971374,0.0010692704,0.000097409145,0.0005786578,0.000042372205,0.0004967554,0.00005722361,0.000040580464,0.00048028713],"genre_scores_gemma":[0.9944157,0.00011188225,0.0033957853,0.0014984175,0.0001308124,0.00004712207,0.0003601077,0.000018550212,0.000021618214],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99837327,0.00010490361,0.0005648115,0.00046889583,0.00015008131,0.000338059],"domain_scores_gemma":[0.9995372,0.000080481135,0.00011896894,0.00006418701,0.000037391266,0.00016175995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016869442,0.0002430782,0.0005139246,0.00017875782,0.000042683947,0.0000058905707,0.000109861794,0.00025739535,0.00026411432],"category_scores_gemma":[0.000036881094,0.0002258086,0.000089818896,0.00028633265,0.00020975809,0.00007574225,0.00008882963,0.00030534147,0.000018522393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028118042,0.00055763335,0.027973581,0.00006621616,0.00005068498,0.0003073062,0.00034424945,0.00000728767,0.96630967,0.00012958949,0.000026917984,0.0014150749],"study_design_scores_gemma":[0.0066513987,0.0006310105,0.15174277,0.000026139283,0.00003056975,0.000029735513,0.00013837928,0.0039398014,0.8358609,0.00029327703,0.0004337219,0.00022229675],"about_ca_topic_score_codex":0.000024807368,"about_ca_topic_score_gemma":0.0000017046631,"teacher_disagreement_score":0.13044876,"about_ca_system_score_codex":0.00011454138,"about_ca_system_score_gemma":0.00015575357,"threshold_uncertainty_score":0.9208208},"labels":[],"label_agreement":null},{"id":"W3084787013","doi":"10.21203/rs.3.rs-62994/v1","title":"Inhibition of Ref(2)P, the Drosophila homologue of p62/SQSTM1, increases lifespan and leads to motor function decline","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Memorial University of Newfoundland","keywords":"Motor function; Drosophila (subgenus); Function (biology); Chemistry; Cell biology; Biology; Internal medicine; Genetics; Physical medicine and rehabilitation; Medicine; Gene","score_opus":0.06998656023433725,"score_gpt":0.39100906930843243,"score_spread":0.3210225090740952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3084787013","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98734295,0.0030258067,0.00012137753,0.006780701,0.00007543918,0.0018009748,0.00040359425,0.00004642099,0.00040273563],"genre_scores_gemma":[0.99665004,0.0013060721,0.0001110379,0.00050529314,0.00060610834,0.00020615336,0.00039379523,0.00004131501,0.00018019867],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9971809,0.00048453608,0.0004832287,0.0004928615,0.0010507496,0.00030774597],"domain_scores_gemma":[0.9975539,0.00045928275,0.00017010699,0.0007495633,0.0007266442,0.0003404913],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011007912,0.00022040922,0.00057814026,0.00036888776,0.00011333247,0.000024291738,0.00019769068,0.0002950581,0.00015558605],"category_scores_gemma":[0.0012372409,0.00015917294,0.00019532845,0.00044590057,0.0004062029,0.00004227402,0.00087705365,0.00094635674,0.000021302825],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.050642714,0.0058732964,0.10724068,0.034551956,0.0025616046,0.0012128089,0.006203445,0.00024469564,0.7118708,0.011011653,0.027802508,0.040783864],"study_design_scores_gemma":[0.0042821895,0.010501409,0.8307659,0.006720255,0.00053185964,0.000046175388,0.0014706437,0.0005052417,0.11081648,0.0299216,0.0038915207,0.0005467007],"about_ca_topic_score_codex":0.000611337,"about_ca_topic_score_gemma":0.000031400443,"teacher_disagreement_score":0.7235252,"about_ca_system_score_codex":0.00008201397,"about_ca_system_score_gemma":0.0004962925,"threshold_uncertainty_score":0.6490884},"labels":[],"label_agreement":null},{"id":"W3085949880","doi":"10.1083/jcb.202004029","title":"Mitophagy pathways in health and disease","year":2020,"lang":"en","type":"review","venue":"The Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":235,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Disease; Medicine; Computational biology; Autophagy; Biology; Genetics; Pathology","score_opus":0.047243700654988674,"score_gpt":0.3477829329134671,"score_spread":0.30053923225847845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3085949880","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00078280625,0.9979375,0.00001144574,0.00065139274,0.0001707591,0.00030456364,0.000017553597,0.0000046549567,0.00011931961],"genre_scores_gemma":[0.0008884024,0.99705297,0.00003239237,0.0015313592,0.00040900856,0.0000026393438,0.000014338609,0.000020215366,0.000048679707],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983223,0.00057752634,0.00072279456,0.00011080158,0.00008213505,0.00018445248],"domain_scores_gemma":[0.9982927,0.0002448042,0.0007112089,0.0001744112,0.000029506831,0.0005474008],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000423993,0.00019574443,0.0014650449,0.00012525822,0.000029452744,0.0000036215558,0.00017617096,0.00011538141,0.0000478675],"category_scores_gemma":[0.00010775155,0.00009798754,0.00026260456,0.00012636422,0.00009923631,0.00001497975,0.000042126736,0.0005729581,0.000014161517],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043228743,0.00013314425,0.000020240386,0.00904181,0.00016869491,0.00047281623,0.00024652568,1.388987e-7,0.000043161122,0.00014584305,0.00047293396,0.9888224],"study_design_scores_gemma":[0.0006956306,0.0007721558,0.000027071079,0.0032608854,0.00032654664,0.00024991806,0.000029970728,0.0000018520735,0.000008995747,0.00082103023,0.99372435,0.00008159192],"about_ca_topic_score_codex":0.0000035178437,"about_ca_topic_score_gemma":2.879276e-7,"teacher_disagreement_score":0.99325144,"about_ca_system_score_codex":0.00006410568,"about_ca_system_score_gemma":0.0017383827,"threshold_uncertainty_score":0.39958158},"labels":[],"label_agreement":null},{"id":"W3086048611","doi":"10.1101/2020.09.10.291344","title":"Proteomics of autophagy deficient macrophages reveals enhanced antimicrobial immunity via the oxidative stress response","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Genentech; AXA Research Fund","keywords":"ATG16L1; Autophagy; Innate immune system; Oxidative stress; Intracellular parasite; Shigella flexneri; Biology; Intracellular; Immunity; Microbiology; Cell biology; Immune system; Immunology; Apoptosis; Biochemistry; Escherichia coli; Gene","score_opus":0.014700784999186901,"score_gpt":0.25133610370699805,"score_spread":0.23663531870781115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3086048611","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893662,0.0013583003,0.0040453556,0.0007228828,0.0005727881,0.00268932,0.00097260985,0.00026656364,0.000005999859],"genre_scores_gemma":[0.99405575,0.00036493028,0.0041615097,0.0006833015,0.00030696992,0.0002620244,0.0000023365594,0.00015238137,0.000010819639],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9961866,0.00079569855,0.00093131326,0.00094104616,0.0005692412,0.0005760686],"domain_scores_gemma":[0.99557096,0.00023665649,0.00097391004,0.00211151,0.0007831129,0.00032384988],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001014611,0.000705696,0.0011463817,0.0002151159,0.00024847462,0.0000874539,0.0008622193,0.0005400749,0.000097675955],"category_scores_gemma":[0.00054945244,0.00058240787,0.00041537997,0.00062982994,0.00047449142,0.00008515815,0.00072327926,0.0013686995,0.00004971874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030236486,0.0005662573,0.00036438496,0.0009469288,0.0005952674,0.00013693931,0.00013769869,0.000044619002,0.9939336,0.000112965994,0.00013461697,0.000003041081],"study_design_scores_gemma":[0.0012521148,0.0002547377,0.095890984,0.0007931416,0.00037724595,6.874655e-8,0.000012047526,0.00013082055,0.90074474,0.000008666663,0.00008443439,0.0004510008],"about_ca_topic_score_codex":0.000045814908,"about_ca_topic_score_gemma":4.9277935e-7,"teacher_disagreement_score":0.0955266,"about_ca_system_score_codex":0.00028488104,"about_ca_system_score_gemma":0.0013489572,"threshold_uncertainty_score":0.99966276},"labels":[],"label_agreement":null},{"id":"W3086571449","doi":"10.1523/jneurosci.1759-19.2020","title":"The GTPase Arl8B Plays a Principle Role in the Positioning of Interstitial Axon Branches by Spatially Controlling Autophagosome and Lysosome Location","year":2020,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Krembil Foundation","funders":"Biotechnology and Biological Sciences Research Council; Royal Society","keywords":"Lysosome; Autophagosome; Cell biology; Autophagy; GTPase; Biology; Neuroscience; Biochemistry","score_opus":0.015193342700446274,"score_gpt":0.27134571904221216,"score_spread":0.2561523763417659,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3086571449","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99130124,0.0011061486,0.0026973255,0.0046120863,0.00009567728,0.00014383267,0.0000026295086,0.0000038605067,0.000037193506],"genre_scores_gemma":[0.99709225,0.00016861604,0.000039023107,0.002582731,0.00010566282,0.0000015109397,3.70761e-7,0.0000043964264,0.00000542319],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99907297,0.000077483346,0.00031718425,0.000098538316,0.00032143676,0.00011236327],"domain_scores_gemma":[0.99934363,0.00015478725,0.00026820268,0.00008086449,0.00007169337,0.00008082411],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034387026,0.000066987544,0.00015491707,0.000040126302,0.00010922188,0.000049123195,0.00018256523,0.000020525657,0.0000017665333],"category_scores_gemma":[0.00035264387,0.00003837783,0.000048272348,0.00020698256,0.00015988658,0.00018109467,0.00001903075,0.00018999931,2.9316232e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009607538,0.00013660413,0.0029813603,0.000033055887,0.000011679911,0.00013641293,0.0027375652,0.0007284859,0.99006003,0.00040321337,0.000029393617,0.0017814476],"study_design_scores_gemma":[0.016932879,0.01097818,0.46574593,0.0011305813,0.00036642616,0.0018806249,0.0032912828,0.21854842,0.27364862,0.0016927382,0.005293559,0.000490778],"about_ca_topic_score_codex":0.000004473207,"about_ca_topic_score_gemma":0.0000010613801,"teacher_disagreement_score":0.7164114,"about_ca_system_score_codex":0.000015826214,"about_ca_system_score_gemma":0.000106588486,"threshold_uncertainty_score":0.15650027},"labels":[],"label_agreement":null},{"id":"W3087085162","doi":"10.1152/ajpheart.00580.2020","title":"Tissue-specific small heat shock protein 20 activation is not associated with traditional autophagy markers in Ossabaw swine with cardiometabolic heart failure","year":2020,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"National Center for Advancing Translational Sciences; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; American Heart Association; U.S. Department of Veterans Affairs","keywords":"Autophagy; Intracellular; Heart failure; Heat shock protein; Medicine; Shock (circulatory); Cell biology; Internal medicine; Biology; Genetics; Gene; Apoptosis","score_opus":0.019528895564812146,"score_gpt":0.23228233705468668,"score_spread":0.21275344148987452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3087085162","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995402,0.0003321066,0.000011700137,0.0037299863,0.00004248354,0.0004015539,0.000025845691,0.000031287003,0.000023074646],"genre_scores_gemma":[0.9934973,0.000031339405,0.00034778376,0.0054874355,0.0004985771,0.000026744676,0.00005533122,0.000045440254,0.0000100404],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99799925,0.0003078065,0.00047031327,0.0005117211,0.0002919457,0.00041897834],"domain_scores_gemma":[0.9988035,0.00010897972,0.00031373577,0.00023605298,0.00019655087,0.00034117885],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016078466,0.00034245086,0.0012981576,0.00021057844,0.00010185833,0.00001123822,0.00012134848,0.00013327399,0.00019885525],"category_scores_gemma":[0.000024731966,0.0002581343,0.00018004978,0.00060674496,0.00073805236,0.00016825713,0.000021439131,0.0006331582,0.000006617768],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0031217823,0.00026244138,0.0019471042,0.000036386784,0.0005519669,0.000008221376,0.0003245698,0.00018105489,0.9926147,0.00004598205,0.000594883,0.00031089262],"study_design_scores_gemma":[0.0038426192,0.0049627395,0.9516264,0.00015786613,0.00011149649,0.00015350535,0.00043414632,0.000084496336,0.035599813,0.0001380236,0.0026045179,0.00028433505],"about_ca_topic_score_codex":0.0000206293,"about_ca_topic_score_gemma":0.0000023811547,"teacher_disagreement_score":0.9570149,"about_ca_system_score_codex":0.00008467725,"about_ca_system_score_gemma":0.00029980164,"threshold_uncertainty_score":0.99998707},"labels":[],"label_agreement":null},{"id":"W3087450283","doi":"10.1139/cjpp-2019-0684","title":"BW373U86 upregulates autophagy by inhibiting the PI3K/Akt pathway and regulating the mTOR pathway to protect cardiomyocytes from hypoxia–reoxygenation injury","year":2020,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"PI3K/AKT/mTOR pathway; Autophagy; Protein kinase B; Viability assay; Chemistry; LY294002; Cell biology; Myocyte; Downregulation and upregulation; Pharmacology; Molecular biology; Signal transduction; Biology; Apoptosis; Biochemistry","score_opus":0.013070524110736836,"score_gpt":0.2489847847171505,"score_spread":0.23591426060641366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3087450283","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.981582,0.005043392,0.00003630604,0.012470771,0.00029525236,0.00042231477,0.00008681316,0.000011172152,0.00005200333],"genre_scores_gemma":[0.98679924,0.00006861677,0.000073050796,0.011786954,0.0011835595,0.000021246307,0.000012662469,0.000019003199,0.000035643632],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870205,0.00033484586,0.00033944074,0.00022497456,0.00009290232,0.00030576103],"domain_scores_gemma":[0.99872774,0.0002753213,0.00022548849,0.00009380511,0.00011935427,0.00055827136],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028712506,0.00017928681,0.00037962061,0.00007025625,0.00038717067,0.000022401702,0.00015615112,0.00012547278,0.0003524088],"category_scores_gemma":[0.000109084474,0.00011083803,0.00009133241,0.00015591893,0.00029633258,0.00008298976,0.000036363424,0.00045531587,0.0000042670567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031282334,0.000010028262,0.00024165431,0.000030750325,0.00029854404,0.000047848152,0.0020277135,0.000033682012,0.9831147,0.000088502995,0.0038731971,0.009920534],"study_design_scores_gemma":[0.0014361915,0.00083059253,0.0154733,0.000050342267,0.00019819384,0.00010190852,0.00036605995,0.00044597022,0.96113443,0.0016987545,0.018094262,0.00017001538],"about_ca_topic_score_codex":0.00034814383,"about_ca_topic_score_gemma":0.000047974743,"teacher_disagreement_score":0.021980312,"about_ca_system_score_codex":0.000043340395,"about_ca_system_score_gemma":0.00046938894,"threshold_uncertainty_score":0.45198438},"labels":[],"label_agreement":null},{"id":"W3088966482","doi":"10.7554/elife.56006","title":"The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo","year":2020,"lang":"en","type":"article","venue":"eLife","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; Biology; Bioenergetics; Bafilomycin; Mitophagy; Cell migration; BAG3; Cell; Neuroscience; Mitochondrion; Biochemistry","score_opus":0.01638383032376608,"score_gpt":0.31178824234742786,"score_spread":0.2954044120236618,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3088966482","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9859018,0.00075429614,0.00026104384,0.012510979,0.000054647506,0.00022891999,0.000019805559,0.000047210116,0.00022131583],"genre_scores_gemma":[0.9954814,0.00009891993,0.000039466522,0.0037388715,0.00017971866,0.000010991271,0.000011297411,0.000015940997,0.0004234173],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99920607,0.000053499,0.00019907876,0.0001819129,0.00018545882,0.00017400864],"domain_scores_gemma":[0.9995466,0.00011868679,0.000042711043,0.00012471757,0.000028304714,0.00013899228],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012133641,0.00010428058,0.00016061551,0.000032493153,0.00006852302,0.000024959083,0.0000764228,0.000050333045,0.00007927074],"category_scores_gemma":[0.00010666493,0.000074699194,0.00004221175,0.00011753204,0.000060249204,0.000058474183,0.000037617116,0.00016725148,0.000019031102],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0052038236,0.0006490984,0.5796074,0.00069352787,0.0011106457,0.0014659036,0.042492494,0.00013703464,0.14153773,0.0061109844,0.032483608,0.1885077],"study_design_scores_gemma":[0.0018228801,0.00036033487,0.9420573,0.000043400123,0.000048097572,0.0000076577435,0.0004375139,0.0073240665,0.013332819,0.00022588638,0.034193337,0.00014671175],"about_ca_topic_score_codex":0.000020719679,"about_ca_topic_score_gemma":0.000028305505,"teacher_disagreement_score":0.36244985,"about_ca_system_score_codex":0.000034278008,"about_ca_system_score_gemma":0.00008151951,"threshold_uncertainty_score":0.30461448},"labels":[],"label_agreement":null},{"id":"W3091803308","doi":"10.4103/1673-5374.295330","title":"Regulation of Parkin-dependent mitophagy by Bcl-2-associated athanogene (BAG) family members","year":2020,"lang":"en","type":"article","venue":"Neural Regeneration Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Toronto Western Hospital; University of Toronto; University Health Network","funders":"","keywords":"Mitophagy; Parkin; Mitochondrion; Cell biology; Autophagy; Biology; PINK1; Neurodegeneration; Neuroscience; Genetics; Apoptosis; Medicine","score_opus":0.09661393761882985,"score_gpt":0.3652324548079951,"score_spread":0.26861851718916524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3091803308","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909654,0.0024899417,0.00009334206,0.004646093,0.00010357124,0.0006117348,0.000043189473,0.00006617885,0.0009805436],"genre_scores_gemma":[0.9951746,0.00038798072,0.00007575165,0.0008362694,0.00029453117,0.000046172645,0.0003485975,0.000033265504,0.0028028656],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99712527,0.00039050885,0.0004061755,0.00039487338,0.0013395806,0.00034362226],"domain_scores_gemma":[0.9986565,0.00010882155,0.000115272225,0.000291012,0.0005180671,0.00031032224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047294557,0.00014821811,0.0002896648,0.00012428264,0.00015394438,0.000033238815,0.00014806096,0.00015626427,0.00046190366],"category_scores_gemma":[0.00033147482,0.00013288268,0.00012125954,0.0005778543,0.00010830183,0.000118069715,0.000050894552,0.00029935708,0.000045337227],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043382408,0.00016446473,0.00088285597,0.00004092406,0.00008977974,0.000023087552,0.00021293419,0.00031324336,0.9735499,0.00015411137,0.019754926,0.004379966],"study_design_scores_gemma":[0.0019482457,0.0007007881,0.010840432,0.000025543673,0.000033514993,0.0000038492317,0.00006434621,0.023270361,0.9595604,0.00008127207,0.0033525075,0.000118765325],"about_ca_topic_score_codex":0.000067120905,"about_ca_topic_score_gemma":0.000008155749,"teacher_disagreement_score":0.022957116,"about_ca_system_score_codex":0.00011016755,"about_ca_system_score_gemma":0.00015686615,"threshold_uncertainty_score":0.54187983},"labels":[],"label_agreement":null},{"id":"W3091859943","doi":"10.1038/s41388-020-01491-w","title":"Targeted degradation of immune checkpoint proteins: emerging strategies for cancer immunotherapy","year":2020,"lang":"en","type":"review","venue":"Oncogene","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"National Natural Science Foundation of China-Yunnan Joint Fund; National Natural Science Foundation of China","keywords":"Endosome; Immunotherapy; Biology; Immune checkpoint; Cancer immunotherapy; Proteasome; Cancer research; Immune system; Autophagy; Cancer; Protein degradation; Cell biology; Immunology; Intracellular; Apoptosis; Biochemistry","score_opus":0.05104745267605933,"score_gpt":0.3744129128980245,"score_spread":0.32336546022196516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3091859943","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00017629116,0.9945353,0.0013366854,0.00012586055,0.00021273189,0.00320621,0.00015960411,0.00011409116,0.0001332241],"genre_scores_gemma":[0.00008103538,0.9950982,0.0017699718,0.00006597025,0.00040873018,0.0015608785,0.000524744,0.00016822923,0.00032225277],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981416,0.00006207567,0.0009537601,0.00035749847,0.00024019304,0.0002448692],"domain_scores_gemma":[0.99856824,0.000039917126,0.00075277133,0.00039726452,0.0001524642,0.00008934511],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016730226,0.00040296107,0.0019322656,0.00012986566,0.000049344104,0.000017572434,0.00018319853,0.00023383269,0.00025426183],"category_scores_gemma":[0.00002790373,0.0003142861,0.001003013,0.00032292138,0.000041076753,0.00007692041,0.000022458144,0.00020081438,0.000007338792],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017850302,0.00011892039,4.648557e-7,0.015579976,0.0014128753,0.000011669317,0.00012495264,0.0000010977182,0.017051931,0.00015316869,0.00006045524,0.965306],"study_design_scores_gemma":[0.0012387405,0.00034549364,0.0000033075544,0.008284103,0.001170635,0.000010108572,0.00008328457,0.000024099352,0.01350881,0.00013990943,0.97490907,0.00028244255],"about_ca_topic_score_codex":0.00009645997,"about_ca_topic_score_gemma":0.0000042171646,"teacher_disagreement_score":0.9748486,"about_ca_system_score_codex":0.00015864735,"about_ca_system_score_gemma":0.001792431,"threshold_uncertainty_score":0.9999309},"labels":[],"label_agreement":null},{"id":"W3091922136","doi":"10.1016/j.mad.2020.111382","title":"Autophagy and heat-shock response impair stress granule assembly during cellular senescence","year":2020,"lang":"en","type":"article","venue":"Mechanisms of Ageing and Development","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; McGill University","keywords":"Autophagy; Senescence; Heat shock; Cell biology; Cellular Aging; Granule (geology); Heat stress; Ageing; Biology; Heat shock protein; Cellular senescence; Fight-or-flight response; Shock (circulatory); Chemistry; Biochemistry; Telomere; Medicine; Genetics; Internal medicine; Phenotype; Apoptosis","score_opus":0.012991654889579056,"score_gpt":0.23172904453430215,"score_spread":0.21873738964472308,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3091922136","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9877478,0.00092337537,0.010562868,0.00038697218,0.000047250178,0.00021303419,0.0000057168495,0.000086811364,0.000026154723],"genre_scores_gemma":[0.992548,0.000071969494,0.0068580606,0.00034681903,0.00003521423,0.000011263985,0.000008178692,0.00002091145,0.00009960689],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988877,0.00005315048,0.00027194427,0.00031254694,0.00024783282,0.00022680976],"domain_scores_gemma":[0.999442,0.000040719486,0.00005447948,0.00013476527,0.000043633067,0.00028444728],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021045307,0.00017846367,0.00030076577,0.000068667905,0.0001461745,0.000019609066,0.00006059625,0.00007121337,0.00003152295],"category_scores_gemma":[0.000038729435,0.00016029566,0.000036428355,0.0000956466,0.000033742435,0.000058984402,0.000087222914,0.00010249002,0.0000050108647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013238636,0.00008480143,0.0007058251,0.0004452503,0.000088942244,0.0009300441,0.0029226013,0.000007662594,0.99114275,0.000108000604,0.000012075079,0.002228186],"study_design_scores_gemma":[0.0014413039,0.00025274686,0.08584156,0.00021587864,0.00002847645,0.000032262284,0.00046341433,0.00026450693,0.9110465,0.00011874539,0.00013013289,0.00016444454],"about_ca_topic_score_codex":0.0000144703445,"about_ca_topic_score_gemma":7.8791027e-7,"teacher_disagreement_score":0.08513573,"about_ca_system_score_codex":0.00002652647,"about_ca_system_score_gemma":0.00013685721,"threshold_uncertainty_score":0.65366673},"labels":[],"label_agreement":null},{"id":"W3091950766","doi":"10.1101/2020.10.09.333435","title":"Autophagy is required for midbrain dopaminergic axon development and their responsiveness to guidance cues","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Université Laval","keywords":"Autophagy; ATG5; Neuroscience; Axon; Biology; Cell biology; Dopaminergic; Midbrain; Axon guidance; Growth cone; Dopamine; Central nervous system; Biochemistry; Apoptosis","score_opus":0.028702175586455665,"score_gpt":0.26649599767041915,"score_spread":0.2377938220839635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3091950766","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9832714,0.005977195,0.0041841194,0.0027395776,0.00072801503,0.002281918,0.00036840205,0.00043994532,0.000009385207],"genre_scores_gemma":[0.9735895,0.0002119289,0.01918519,0.0050043557,0.0006373892,0.0011018893,0.000002139435,0.00019713267,0.00007052267],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968773,0.000109040535,0.0006953424,0.0013837537,0.00033270125,0.00060184643],"domain_scores_gemma":[0.99717915,0.00014735336,0.0003085952,0.0011137136,0.00053845753,0.0007127209],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005360735,0.0007392469,0.0010213024,0.00028443048,0.00019688577,0.00012052367,0.00039847736,0.0004485816,0.00003499811],"category_scores_gemma":[0.00040708433,0.00068849855,0.00020409361,0.00041384902,0.00010569672,0.000088932145,0.0004381968,0.00037441918,0.000038754966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016481625,0.00022073105,0.0014677119,0.0020224447,0.00071349606,0.00021096879,0.00032242245,0.000005364919,0.98997205,0.0006328413,0.0027163164,0.00006745808],"study_design_scores_gemma":[0.0014692036,0.00023397664,0.07282348,0.0009846666,0.00013031458,6.579614e-8,0.0000128571,0.0002168924,0.8442383,0.000013021916,0.07914096,0.0007362881],"about_ca_topic_score_codex":0.000007809652,"about_ca_topic_score_gemma":9.520553e-7,"teacher_disagreement_score":0.1457338,"about_ca_system_score_codex":0.00029797133,"about_ca_system_score_gemma":0.0015027925,"threshold_uncertainty_score":0.9995566},"labels":[],"label_agreement":null},{"id":"W3092101056","doi":"10.1080/15548627.2020.1821548","title":"BNIP3L/Nix-induced mitochondrial fission, mitophagy, and impaired myocyte glucose uptake are abrogated by PRKA/PKA phosphorylation","year":2020,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":121,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada; Athabasca University; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Children's Hospital Research Institute of Manitoba; Canadian Institutes of Health Research; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Mitophagy; Lipotoxicity; Biology; Mitochondrial fission; Cell biology; Mitochondrion; FIS1; Autophagy; MFN2; Internal medicine; Endocrinology; mitochondrial fusion; Insulin resistance; Biochemistry; Insulin; Apoptosis; Mitochondrial DNA","score_opus":0.018639125852316505,"score_gpt":0.25978543202888194,"score_spread":0.24114630617656543,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092101056","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9870367,0.007118204,0.00014201134,0.0030662422,0.0006146033,0.0010512554,0.00008679036,0.00053731474,0.0003468779],"genre_scores_gemma":[0.9921232,0.0004107189,0.00042593182,0.0047079837,0.0008475772,0.00007126042,0.00028848945,0.00010011337,0.0010247612],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99732864,0.00010464642,0.00063959655,0.00083099026,0.00053592195,0.00056017685],"domain_scores_gemma":[0.99806947,0.00008498332,0.00030211086,0.0004990875,0.00016421844,0.000880157],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000101422986,0.00048757816,0.000707814,0.00009435728,0.00024064854,0.0000783585,0.00020468784,0.00037004892,0.00089734624],"category_scores_gemma":[0.00024755285,0.00044155988,0.00022841216,0.00046435287,0.00010690546,0.0002668279,0.00009152069,0.00040469723,0.00020442616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028013682,0.00054106594,0.0014286666,0.00019020798,0.00044818406,0.00054387224,0.002043906,0.000005216474,0.91661143,0.000098298704,0.046311617,0.028976193],"study_design_scores_gemma":[0.011833937,0.0012022903,0.0825983,0.00018099419,0.0003100043,0.0000689684,0.00032699067,0.003156927,0.8547302,0.00025158146,0.044680472,0.00065935677],"about_ca_topic_score_codex":0.00007288506,"about_ca_topic_score_gemma":0.0000033327085,"teacher_disagreement_score":0.081169635,"about_ca_system_score_codex":0.0000949243,"about_ca_system_score_gemma":0.00021058934,"threshold_uncertainty_score":0.9998036},"labels":[],"label_agreement":null},{"id":"W3092243963","doi":"10.1139/cjpp-2020-0341","title":"Cyanidin-3-O-glucoside attenuates high glucose–induced podocyte dysfunction by inhibiting apoptosis and promoting autophagy via activation of SIRT1/AMPK pathway","year":2020,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"AMPK; Downregulation and upregulation; Autophagy; Podocyte; Apoptosis; Cell biology; Chemistry; Flow cytometry; Cancer research; Biology; Endocrinology; Molecular biology; Protein kinase A; Kidney; Biochemistry; Kinase","score_opus":0.01523074082580999,"score_gpt":0.24700272077164645,"score_spread":0.23177197994583645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092243963","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99572724,0.0010467367,0.00007040932,0.0026478623,0.00026562897,0.00019418244,0.000018692499,0.000009928313,0.000019300027],"genre_scores_gemma":[0.99622995,0.00014850932,0.00005312532,0.00308616,0.00042591087,0.0000049279824,0.000025417521,0.000018735322,0.0000072391563],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885494,0.0001672663,0.0004160194,0.00020925677,0.00007554686,0.0002770016],"domain_scores_gemma":[0.99866503,0.00014014832,0.00041498162,0.00004345852,0.00016458966,0.00057181495],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017212702,0.00016814146,0.00046810627,0.00013782365,0.0001487921,0.000006743204,0.00006289976,0.00016355645,0.00031631472],"category_scores_gemma":[0.00007149259,0.00015203863,0.00006947946,0.00014626884,0.00015999231,0.00015192758,0.000016260978,0.00038268176,0.0000019679658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043403485,0.00003786148,0.0006287746,0.0001732819,0.00026088854,0.0000294746,0.00069757504,0.000008037427,0.9911365,0.000030245532,0.0004142915,0.0061490205],"study_design_scores_gemma":[0.0024430845,0.0012167027,0.005822874,0.000060479026,0.00017927987,0.0000768038,0.00011402812,0.00042201983,0.9889874,0.00031900627,0.00024372501,0.00011460838],"about_ca_topic_score_codex":0.00035937323,"about_ca_topic_score_gemma":0.000014253298,"teacher_disagreement_score":0.006034412,"about_ca_system_score_codex":0.00005305401,"about_ca_system_score_gemma":0.00037986552,"threshold_uncertainty_score":0.61999553},"labels":[],"label_agreement":null},{"id":"W3092543824","doi":"10.1002/jcp.30079","title":"Autophagy displays divergent roles during intermittent amino acid starvation and toxic stress‐induced senescence in cultured skeletal muscle cells","year":2020,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Senescence; Cell biology; Programmed cell death; Biology; Context (archaeology); Staurosporine; Myocyte; Apoptosis; Biochemistry; Phosphorylation; Protein kinase A","score_opus":0.012557058189821611,"score_gpt":0.2368628553469516,"score_spread":0.22430579715712998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092543824","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99801683,0.0010811486,0.00017278481,0.00038492563,0.00017260721,0.00014383855,0.0000068547993,0.000010438454,0.000010590924],"genre_scores_gemma":[0.9988038,0.0003780316,0.00009842573,0.00030164167,0.00037116325,0.0000024639571,0.000012003344,0.000014204203,0.000018275854],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888355,0.00009545032,0.0004292728,0.00019819335,0.00018789594,0.00020565563],"domain_scores_gemma":[0.9993097,0.000018120196,0.00028370964,0.0001132446,0.0000743077,0.00020086947],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006932903,0.00016195947,0.00041026805,0.00008091647,0.000043926717,0.000010076019,0.00011128413,0.00009578145,0.000081629805],"category_scores_gemma":[0.000026501073,0.00012667177,0.00013440802,0.00010708161,0.000052064475,0.00013149329,0.00006264773,0.00029045585,0.0000066574994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003270177,0.00020423502,0.00084575266,0.00012379336,0.00008228704,0.0003614637,0.0011395818,0.000060034126,0.9958909,0.000014320639,0.00002428783,0.0009262986],"study_design_scores_gemma":[0.0016609296,0.00047395416,0.27033725,0.00009380749,0.00005212994,0.000017319522,0.00031211408,0.0005452017,0.7263193,0.000052096744,0.00004327001,0.0000926101],"about_ca_topic_score_codex":0.000004130432,"about_ca_topic_score_gemma":0.0000016897072,"teacher_disagreement_score":0.2695716,"about_ca_system_score_codex":0.000049395294,"about_ca_system_score_gemma":0.00005100156,"threshold_uncertainty_score":0.5165525},"labels":[],"label_agreement":null},{"id":"W3092614728","doi":"10.2337/db19-0762","title":"Cardiac Autophagy Deficiency Attenuates ANP Production and Disrupts Myocardial-Adipose Cross Talk, Leading to Increased Fat Accumulation and Metabolic Dysfunction","year":2020,"lang":"en","type":"article","venue":"Diabetes","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto; York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Internal medicine; Endocrinology; Autophagy; Adipose tissue; Insulin resistance; Atrial natriuretic peptide; Respiratory exchange ratio; Insulin; Medicine; Biology; Biochemistry; Heart rate","score_opus":0.024623251490921046,"score_gpt":0.29653706135259866,"score_spread":0.2719138098616776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092614728","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98970675,0.008112776,0.0000345268,0.0008573902,0.00034947906,0.00064230367,0.000027625625,0.00016321258,0.00010596101],"genre_scores_gemma":[0.9976307,0.00020614147,0.0000962942,0.0010555931,0.00078740425,0.00006112855,0.000071437215,0.000033649467,0.0000576438],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986705,0.000076639684,0.0002279724,0.0005026828,0.00022619513,0.000295975],"domain_scores_gemma":[0.99923515,0.00006451499,0.00007183578,0.00019680486,0.00009725369,0.0003344245],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019168855,0.00021365455,0.0004119923,0.000107180895,0.00019304146,0.000092366485,0.000042986816,0.000085762746,0.000019194773],"category_scores_gemma":[0.0004879766,0.00019360438,0.0000858175,0.00033714194,0.0000906008,0.00031868127,0.00004863671,0.0001137926,0.000030702027],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019226072,0.00007042447,0.5504957,0.00018950524,0.00020453014,0.0000073956085,0.0012824641,0.00012328761,0.42759663,0.00012548945,0.00034964984,0.01936269],"study_design_scores_gemma":[0.0007109716,0.00023930713,0.7508629,0.000057699646,0.00034727494,0.000002677519,0.00009516441,0.00087299466,0.24506372,0.00012573085,0.0013895289,0.0002320472],"about_ca_topic_score_codex":0.000031333384,"about_ca_topic_score_gemma":7.8693915e-7,"teacher_disagreement_score":0.20036723,"about_ca_system_score_codex":0.000026044889,"about_ca_system_score_gemma":0.000027601329,"threshold_uncertainty_score":0.78949577},"labels":[],"label_agreement":null},{"id":"W3092629941","doi":"10.1039/d0fo00949k","title":"Apigenin induced autophagy and stimulated autophagic lipid degradation","year":2020,"lang":"en","type":"article","venue":"Food & Function","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nutrasource","funders":"Jilin University","keywords":"Autophagy; Apigenin; Degradation (telecommunications); Cell biology; Chemistry; Flux (metallurgy); Lipid droplet; Biochemistry; Biology; Flavonoid; Apoptosis; Telecommunications","score_opus":0.039235896518101346,"score_gpt":0.25506572145990564,"score_spread":0.2158298249418043,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092629941","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950675,0.0010182582,0.0014315718,0.0009431466,0.0003171043,0.0003720083,0.000006223383,0.00033622637,0.00050796015],"genre_scores_gemma":[0.997118,0.00003594662,0.00012791617,0.0019812488,0.0004873121,0.000019093068,0.00009750653,0.000028875593,0.00010412342],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990459,0.00004388027,0.00021337249,0.00031353516,0.00020526002,0.00017803074],"domain_scores_gemma":[0.999432,0.000025954523,0.00007423978,0.00015972716,0.00006611841,0.00024195031],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006865716,0.00016188364,0.00021309979,0.000070913586,0.00009595386,0.000024763065,0.000038077706,0.00012856114,0.00046079318],"category_scores_gemma":[0.00006047821,0.00014787311,0.00006703318,0.00027227306,0.000024903542,0.00015046004,0.00002122556,0.00018018742,0.00013138367],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.03244786,0.0007964784,0.008022773,0.00042016362,0.0016185732,0.00010798477,0.0027094516,0.00015530808,0.6608771,0.0029623173,0.0020139257,0.28786805],"study_design_scores_gemma":[0.018310666,0.09261686,0.63633513,0.00016291387,0.00152055,0.000109542816,0.00048738322,0.03716271,0.18398854,0.0015295641,0.026683474,0.0010926746],"about_ca_topic_score_codex":0.000008910552,"about_ca_topic_score_gemma":0.0000011697252,"teacher_disagreement_score":0.62831235,"about_ca_system_score_codex":0.0000341788,"about_ca_system_score_gemma":0.00007177335,"threshold_uncertainty_score":0.60300905},"labels":[],"label_agreement":null},{"id":"W3092692652","doi":"10.1007/s13311-020-00952-0","title":"Withaferin-A Treatment Alleviates TAR DNA-Binding Protein-43 Pathology and Improves Cognitive Function in a Mouse Model of FTLD","year":2020,"lang":"en","type":"article","venue":"Neurotherapeutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Fondation Brain Canada; ALS Society of Canada","keywords":"Withaferin A; Withania somnifera; Frontotemporal lobar degeneration; Autophagy; Biology; Neuroinflammation; Neuroscience; Frontotemporal dementia; Cell biology; Pathology; Dementia; Medicine; Biochemistry; Immunology; Inflammation","score_opus":0.043840850680287896,"score_gpt":0.2771291745486622,"score_spread":0.2332883238683743,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092692652","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976151,0.00034467425,0.00036704415,0.0005282359,0.00001667746,0.0009315557,0.000036003705,0.000047534308,0.00011317494],"genre_scores_gemma":[0.9970641,0.00033859373,0.00018113025,0.0019826535,0.00003724968,0.000085528525,0.0000108424065,0.000038785856,0.0002610857],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919194,0.00004778963,0.00021653168,0.00026401234,0.00010897106,0.00017077486],"domain_scores_gemma":[0.99963516,0.00003355341,0.00008315394,0.000112695685,0.000038425547,0.00009700001],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003496906,0.00017302363,0.00030455782,0.00006610399,0.00002785337,0.000006844337,0.000034011493,0.00008270858,0.000017737799],"category_scores_gemma":[0.000014718035,0.00014448329,0.00005542043,0.000091034795,0.00008025047,0.000049174294,0.000012644586,0.00011500173,0.0000040244645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020147972,0.00033066538,0.0022487463,0.000088103516,0.00014064767,0.00005237381,0.0017477989,0.000020147132,0.983977,0.00011830208,9.812911e-7,0.009260391],"study_design_scores_gemma":[0.0091383075,0.0075190472,0.0036656084,0.00009078867,0.00034993066,0.000019539491,0.00048372702,0.018850286,0.95907533,0.0003697573,0.00018593822,0.0002517482],"about_ca_topic_score_codex":0.0000063061593,"about_ca_topic_score_gemma":0.000003945374,"teacher_disagreement_score":0.024901723,"about_ca_system_score_codex":0.000022526572,"about_ca_system_score_gemma":0.00006634485,"threshold_uncertainty_score":0.5891858},"labels":[],"label_agreement":null},{"id":"W3092730512","doi":"10.1371/journal.pgen.1009070","title":"PE homeostasis rebalanced through mitochondria-ER lipid exchange prevents retinal degeneration in Drosophila","year":2020,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Directorate for Biological Sciences; Institute of Genetics; National Natural Science Foundation of China","keywords":"Biology; Cell biology; Mitochondrion; Endoplasmic reticulum; Retinal degeneration; Visual phototransduction; Phosphatidylethanolamine; Biochemistry; Retinal; Phospholipid; Phosphatidylcholine","score_opus":0.046118344647339965,"score_gpt":0.2868480142777621,"score_spread":0.2407296696304221,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092730512","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990782,0.004432942,0.00016092364,0.0028908385,0.00016677717,0.0006393736,0.00003036067,0.00006837337,0.0008284131],"genre_scores_gemma":[0.98758817,0.0026457312,0.0035495013,0.004528508,0.0012582999,0.00007448302,0.00012536978,0.000049348368,0.00018060383],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986807,0.0000681051,0.00030265158,0.00034537347,0.0003399938,0.0002631492],"domain_scores_gemma":[0.9993735,0.000019768204,0.00008441817,0.00029101616,0.00006207844,0.00016922633],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000040907667,0.000182867,0.0002917813,0.000041066483,0.000047241454,0.000017469461,0.00011467203,0.00012346967,0.0003369295],"category_scores_gemma":[0.00005652588,0.00017774335,0.00008245459,0.0002600513,0.000038399987,0.000057911857,0.000045105524,0.00017583858,0.00008764966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016671492,0.0015291716,0.044672906,0.00087199104,0.0002997896,0.00031636195,0.009845304,0.00013844986,0.92377293,0.00014713607,0.009263493,0.007475303],"study_design_scores_gemma":[0.0054606996,0.0012020442,0.015544175,0.00027515963,0.00028691188,0.000014442941,0.00014633307,0.0044708196,0.9571448,0.00091419765,0.01406521,0.0004752084],"about_ca_topic_score_codex":0.0000021402134,"about_ca_topic_score_gemma":0.0000042758024,"teacher_disagreement_score":0.033371855,"about_ca_system_score_codex":0.000049994975,"about_ca_system_score_gemma":0.00007603232,"threshold_uncertainty_score":0.7248163},"labels":[],"label_agreement":null},{"id":"W3092854192","doi":"10.1155/2020/8345246","title":"Upregulation of CFTR Protects against Palmitate-Induced Endothelial Dysfunction by Enhancing Autophagic Flux","year":2020,"lang":"en","type":"article","venue":"Oxidative Medicine and Cellular Longevity","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China; Guangzhou Medical University","keywords":"Downregulation and upregulation; Autophagy; Endothelial dysfunction; Cell biology; Endothelial stem cell; ATG5; Endocrinology; Chemistry; Internal medicine; Biology; Apoptosis; Medicine; Biochemistry","score_opus":0.029084232362828085,"score_gpt":0.26163021965290256,"score_spread":0.23254598729007447,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092854192","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9856516,0.002072534,0.008148315,0.0014481941,0.00011468749,0.00086509564,0.000018499311,0.00007814918,0.0016029184],"genre_scores_gemma":[0.99769765,0.0001209449,0.00012850986,0.0010489475,0.00041298356,0.000031086034,0.00022406928,0.000029450906,0.00030637017],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983419,0.0001522087,0.0004302497,0.00042555647,0.00041809055,0.00023198735],"domain_scores_gemma":[0.9989922,0.00008509484,0.00025099484,0.0002321856,0.00013632659,0.00030322245],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029533682,0.00026121765,0.00057947874,0.00007533044,0.00009829662,0.000007025446,0.000071187154,0.00012343109,0.0004001432],"category_scores_gemma":[0.00026235968,0.00020397977,0.00009083848,0.0002579275,0.00018583308,0.00013607994,0.000035659275,0.00025472057,0.000019210664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042840294,0.00011007019,0.000655635,0.0003016193,0.0001312413,0.000042699132,0.0016918572,0.0000016559401,0.9790434,0.000071515344,0.00049909373,0.017022766],"study_design_scores_gemma":[0.0035093643,0.0013905677,0.004004235,0.00025583865,0.00017471329,0.0000051802904,0.00059932173,0.00079190795,0.9874826,0.00013578488,0.0014755814,0.00017489195],"about_ca_topic_score_codex":0.000039200713,"about_ca_topic_score_gemma":0.0000020126088,"teacher_disagreement_score":0.016847875,"about_ca_system_score_codex":0.00003933316,"about_ca_system_score_gemma":0.00007662016,"threshold_uncertainty_score":0.83180535},"labels":[],"label_agreement":null},{"id":"W3093616181","doi":"10.1101/2020.10.23.353219","title":"The papain-like protease of coronaviruses cleaves ULK1 to disrupt host autophagy","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Biology; Coronavirus; Autophagy; Proteases; Virology; ULK1; Protein kinase domain; Betacoronavirus; Viral replication; Mouse hepatitis virus; Cell biology; Protein kinase A; Virus; Kinase; Genetics; Mutant; Medicine; Coronavirus disease 2019 (COVID-19); Gene; Biochemistry; Enzyme","score_opus":0.02152508867820203,"score_gpt":0.2663964630954918,"score_spread":0.2448713744172898,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3093616181","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883231,0.0041864426,0.00037544992,0.0019622364,0.0011353851,0.003054979,0.0004469467,0.000491661,0.00002381331],"genre_scores_gemma":[0.9941948,0.0005215225,0.0012341657,0.002497998,0.00072040467,0.0006011337,7.3383626e-7,0.00020010081,0.000029148447],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99655175,0.00019670624,0.00082631933,0.0010384246,0.00073400384,0.00065277016],"domain_scores_gemma":[0.995928,0.00017322676,0.0005206589,0.0020230834,0.0005127475,0.0008423037],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004799171,0.00069046434,0.0009623425,0.00016054024,0.0002564834,0.00013028934,0.0007694416,0.0004187474,0.000095875504],"category_scores_gemma":[0.00056614063,0.00055184506,0.00039180892,0.00054296723,0.00031005777,0.000082566236,0.0006072169,0.00086213916,0.00017270856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001484557,0.0007037622,0.010314502,0.0016185499,0.0011854743,0.0005487716,0.00010585767,0.000017237942,0.97979504,0.0018223762,0.0023630937,0.000040787927],"study_design_scores_gemma":[0.0013072923,0.00043524927,0.40824616,0.0008671993,0.00047891197,5.6618966e-8,0.00001794058,0.00011987982,0.56073546,0.000011143368,0.02703954,0.00074119226],"about_ca_topic_score_codex":0.00006547616,"about_ca_topic_score_gemma":0.0000018359156,"teacher_disagreement_score":0.41905957,"about_ca_system_score_codex":0.00020486387,"about_ca_system_score_gemma":0.0013144902,"threshold_uncertainty_score":0.99969333},"labels":[],"label_agreement":null},{"id":"W3094492339","doi":"10.1242/jcs.252015","title":"<i>Vibrio cholerae</i> cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy","year":2020,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Kempestiftelserna; European Research Council; Knut och Alice Wallenbergs Stiftelse; Cancerfonden","keywords":"Autophagy; Biology; Lipid-anchored protein; Cell biology; Vibrio cholerae; ATG5; BAG3; Innate immune system; Microbiology; Immune system; Bacteria; Biochemistry; Immunology; Apoptosis","score_opus":0.024794123537024527,"score_gpt":0.29152206126955343,"score_spread":0.2667279377325289,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3094492339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929763,0.00040321468,0.00021497573,0.0035367615,0.00016154753,0.00019978573,0.000004026213,0.000008824898,0.0024945734],"genre_scores_gemma":[0.9960178,0.00006657637,0.00068607053,0.002727473,0.00046818232,0.0000022835904,9.715428e-7,0.000009694965,0.000020962098],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972617,0.00013784575,0.0008489486,0.000238007,0.0011891421,0.00032435966],"domain_scores_gemma":[0.9985583,0.00017344924,0.00056572794,0.00020733623,0.0002038572,0.00029133965],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016535819,0.00014111598,0.00040071164,0.00015298942,0.00010121111,0.00004892045,0.00046561463,0.00008699603,0.000078820936],"category_scores_gemma":[0.00042558697,0.00009234159,0.00016727748,0.00089233235,0.00048152107,0.00032042258,0.000070441056,0.0006269519,0.0000074462587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044358204,0.00030700752,0.00056742586,0.000039404265,0.000009165159,0.00043988603,0.0023237113,0.00011359249,0.99337256,0.00010200541,0.00019841638,0.0020832208],"study_design_scores_gemma":[0.0032940486,0.00123107,0.056873206,0.00019534679,0.00004761653,0.00021761928,0.0004178499,0.001304698,0.93537325,0.00010541324,0.00081672595,0.00012314005],"about_ca_topic_score_codex":0.000058184953,"about_ca_topic_score_gemma":0.000007954965,"teacher_disagreement_score":0.057999317,"about_ca_system_score_codex":0.00010279401,"about_ca_system_score_gemma":0.0018245033,"threshold_uncertainty_score":0.37655807},"labels":[],"label_agreement":null},{"id":"W3094721542","doi":"10.1038/s41598-020-76227-7","title":"Coxsackievirus infection induces a non-canonical autophagy independent of the ULK and PI3K complexes","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; St. Paul's Hospital; University of British Columbia","funders":"University of British Columbia; Canadian Institutes of Health Research; Mitacs; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada; ALS Society of Canada; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Coxsackievirus; PI3K/AKT/mTOR pathway; Virology; Computer science; Biology; Non canonical; Cell biology; Computational biology; Genetics; Enterovirus; Signal transduction; Virus; Apoptosis","score_opus":0.026621267656030886,"score_gpt":0.28407353947533626,"score_spread":0.25745227181930536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3094721542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99607635,0.00042641055,0.000040040544,0.00053499773,0.0014189302,0.000395684,0.0000026100759,0.00003603812,0.0010689711],"genre_scores_gemma":[0.9990102,0.00001794803,0.00003596565,0.00037756396,0.00009153175,0.000010092968,0.000007315708,0.000010188594,0.00043920954],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9984958,0.000039877596,0.0003913598,0.00041674142,0.000498124,0.00015807991],"domain_scores_gemma":[0.9989956,0.000021827054,0.00025124266,0.00044583192,0.000103267266,0.0001822401],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038247244,0.00011033143,0.00025438936,0.000051575873,0.0001733486,0.000056680747,0.000068315945,0.00006971772,0.0001985041],"category_scores_gemma":[0.00013116066,0.00007294478,0.00011399557,0.00036618905,0.00039686952,0.00008295149,0.00009853811,0.0001596589,0.0000087469425],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020847001,0.0004183351,0.12099901,0.00027628551,0.00020340935,0.0005421771,0.0021170985,0.000026964653,0.8617636,0.00028622666,0.0074911485,0.005667284],"study_design_scores_gemma":[0.0007036048,0.00022731778,0.5095333,0.000112999456,0.00012789077,0.00039000396,0.00006787933,0.0002459885,0.47157317,0.0016056004,0.015272068,0.00014018528],"about_ca_topic_score_codex":0.00006780549,"about_ca_topic_score_gemma":0.00000973436,"teacher_disagreement_score":0.3901904,"about_ca_system_score_codex":0.00002236635,"about_ca_system_score_gemma":0.00030774352,"threshold_uncertainty_score":0.29746017},"labels":[],"label_agreement":null},{"id":"W3094819482","doi":"10.1007/s00109-020-01999-4","title":"Toll-interacting protein impacts on inflammation, autophagy, and vacuole trafficking in human disease","year":2020,"lang":"en","type":"review","venue":"Journal of Molecular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Autophagy; Vacuole; Cell biology; Biology; Intracellular; Inflammation; Signal transduction; Disease; Immunology; Cytoplasm; Medicine; Pathology; Apoptosis; Genetics","score_opus":0.02818448365311056,"score_gpt":0.3671786962916577,"score_spread":0.3389942126385472,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3094819482","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.041155197,0.9560166,0.00004326327,0.0014843957,0.00015003285,0.000946039,0.0000032861283,0.00002076162,0.00018040864],"genre_scores_gemma":[0.06427321,0.93341506,0.000096980395,0.0006490851,0.0013585078,0.00002283844,0.00003765051,0.000100873884,0.000045779783],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969963,0.00026039704,0.0014820703,0.00029076068,0.0007019861,0.00026848307],"domain_scores_gemma":[0.9974485,0.00013450651,0.0013065231,0.00027417493,0.00012654642,0.0007097541],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00060999114,0.0004506017,0.0021924113,0.00066445046,0.00005387915,0.000024764287,0.00018265059,0.00016704884,0.000098612836],"category_scores_gemma":[0.0010852307,0.00030612774,0.00041059963,0.0003344726,0.0000778718,0.000104035935,0.000037608137,0.0011221446,0.0000049978385],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00057019625,0.00029784592,0.000019095334,0.020656908,0.0010099732,0.035774164,0.00095091783,0.000012394804,0.0069371685,0.00023996207,0.00035684495,0.93317455],"study_design_scores_gemma":[0.008641349,0.003495538,0.0006873827,0.3459119,0.0046052737,0.0017618051,0.00022964434,0.000086933906,0.0011626172,0.0003117255,0.6324341,0.0006717207],"about_ca_topic_score_codex":0.000004055939,"about_ca_topic_score_gemma":5.5160706e-7,"teacher_disagreement_score":0.9325028,"about_ca_system_score_codex":0.00022065072,"about_ca_system_score_gemma":0.00056258147,"threshold_uncertainty_score":0.9999391},"labels":[],"label_agreement":null},{"id":"W3094844018","doi":"10.1016/j.redox.2020.101776","title":"Mono-2-ethylhexyl phthalate drives progression of PINK1-parkin-mediated mitophagy via increasing mitochondrial ROS to exacerbate cytotoxicity","year":2020,"lang":"en","type":"article","venue":"Redox Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":108,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China; Hangzhou Municipal Health and Family Planning Commission","keywords":"Mitophagy; Parkin; PINK1; Reactive oxygen species; Mitochondrion; Cell biology; Programmed cell death; Mitochondrial ROS; Oxidative stress; Chemistry; Phthalate; Autophagy; Biology; Biochemistry; Apoptosis; Internal medicine; Medicine","score_opus":0.015708756382263378,"score_gpt":0.30484211171821246,"score_spread":0.2891333553359491,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3094844018","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942697,0.0012273036,0.0011079131,0.0014461443,0.0003593283,0.001053047,0.00005528274,0.00017028734,0.0003109377],"genre_scores_gemma":[0.99469525,0.00013756308,0.0027224422,0.0013183544,0.0008350894,0.00006206316,0.00015057277,0.000044683322,0.000034003464],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978456,0.00031515272,0.0005727785,0.0005899129,0.00020570014,0.00047088764],"domain_scores_gemma":[0.9985126,0.00019441504,0.00025566958,0.0003761742,0.0001264563,0.00053467887],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015627984,0.00030778474,0.0007710801,0.00013404228,0.000080751466,0.000009631893,0.00022498323,0.0003482908,0.00025066553],"category_scores_gemma":[0.00045801967,0.00024848038,0.00020321259,0.00039937982,0.00020884337,0.00006211241,0.0001405226,0.00027850573,0.00011575036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003468345,0.00022722459,0.012563302,0.000086778164,0.0002121086,0.000097082884,0.000565567,0.0000064809024,0.97612274,0.000036749483,0.00023625318,0.006377363],"study_design_scores_gemma":[0.0043123476,0.0031571446,0.054983728,0.00022873396,0.00014318588,0.00007146735,0.000058746256,0.0008520508,0.9322711,0.0005075311,0.0030317197,0.00038222995],"about_ca_topic_score_codex":0.00006121696,"about_ca_topic_score_gemma":0.0000018021622,"teacher_disagreement_score":0.04385163,"about_ca_system_score_codex":0.000049987364,"about_ca_system_score_gemma":0.00014199638,"threshold_uncertainty_score":0.9999967},"labels":[],"label_agreement":null},{"id":"W3095213530","doi":"10.1182/blood-2020-142671","title":"Dichotomous Regulation of Lysosomes By MYC and Tfeb Controls Hematopoietic Stem Cell Fate","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto; University Health Network","funders":"","keywords":"Cell biology; Stem cell; Haematopoiesis; Biology; Hematopoietic stem cell; Progenitor cell; Cell fate determination; Endocytosis; Cell; Biochemistry; Transcription factor","score_opus":0.008574327165201163,"score_gpt":0.2188745827493976,"score_spread":0.21030025558419646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3095213530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99198985,0.00597307,0.000074950665,0.00057997665,0.000014875742,0.00028985238,0.00002151006,0.0000457097,0.0010102033],"genre_scores_gemma":[0.9987549,0.00014987114,0.000044038305,0.0006253266,0.00005302214,0.0000098838245,0.000015336656,0.000014774653,0.00033284893],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994035,0.000022186414,0.00017898786,0.00014812326,0.00014474493,0.000102481215],"domain_scores_gemma":[0.999592,0.00003260342,0.00008088399,0.00013109602,0.000028836579,0.00013457926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000036108828,0.00008911052,0.00024919794,0.000019076673,0.000021713053,0.000006754621,0.00003732608,0.000050632727,0.00007429377],"category_scores_gemma":[0.000005929387,0.000075094315,0.000050568287,0.0000689157,0.000039240946,0.000034156892,0.00001259788,0.00005159504,0.000011433349],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031222892,0.0006649055,0.011207143,0.00054486695,0.00024081655,0.000044956436,0.0016315453,0.0000017089782,0.98228323,0.0002724461,0.0011046916,0.0016914853],"study_design_scores_gemma":[0.010638473,0.00055107824,0.013328855,0.00007087144,0.00048614433,0.000019631658,0.00019112491,0.00021366175,0.9730571,0.0002860972,0.0010284939,0.00012849933],"about_ca_topic_score_codex":0.0000029801759,"about_ca_topic_score_gemma":9.6067794e-8,"teacher_disagreement_score":0.010326244,"about_ca_system_score_codex":0.0000031482355,"about_ca_system_score_gemma":0.00002187262,"threshold_uncertainty_score":0.30622572},"labels":[],"label_agreement":null},{"id":"W3096137085","doi":"10.18632/aging.103786","title":"LncRNA-modulated autophagy in plaque cells: a new paradigm of gene regulation in atherosclerosis?","year":2020,"lang":"en","type":"review","venue":"Aging","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"","keywords":"Autophagy; Cell biology; Gene; Biology; Cancer research; Genetics; Apoptosis","score_opus":0.048898598003960084,"score_gpt":0.32918108480032277,"score_spread":0.2802824867963627,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3096137085","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0036660507,0.99489456,0.00012219632,0.000112581656,0.00012812528,0.00086569705,0.000010942253,0.00005738931,0.00014244518],"genre_scores_gemma":[0.010498643,0.9884451,0.00031764404,0.0001297624,0.00019595449,0.00003394837,0.00012850881,0.00007734769,0.00017309518],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981174,0.00012830796,0.0008372837,0.00043102438,0.00021834862,0.000267677],"domain_scores_gemma":[0.9990166,0.00008165564,0.00035048745,0.00038985597,0.000013548994,0.00014788064],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016389193,0.00033148826,0.0016418697,0.00033054955,0.000015464542,0.000011166018,0.00015971804,0.00026790888,0.00011684916],"category_scores_gemma":[0.000022335078,0.00030140334,0.00029766755,0.00074450485,0.000028984683,0.00006754431,0.000031930962,0.00038095925,0.000038183825],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058248635,0.00021264183,0.00016404106,0.008583525,0.00028015787,0.00028685716,0.0011339238,0.000074239906,0.0014973222,0.00021114491,0.00019422779,0.9873037],"study_design_scores_gemma":[0.0072039105,0.00027488428,0.010587427,0.09426601,0.0014912062,0.00008417994,0.000042113155,0.0022322594,0.007245863,0.0011022092,0.87426776,0.0012021682],"about_ca_topic_score_codex":0.00024685793,"about_ca_topic_score_gemma":0.000012998855,"teacher_disagreement_score":0.9861015,"about_ca_system_score_codex":0.00021108454,"about_ca_system_score_gemma":0.0005163155,"threshold_uncertainty_score":0.9999438},"labels":[],"label_agreement":null},{"id":"W3096636232","doi":"10.1152/japplphysiol.00542.2020","title":"Autophagy and heat: a potential role for heat therapy to improve autophagic function in health and disease","year":2020,"lang":"en","type":"review","venue":"Journal of Applied Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; Novo Nordisk Fonden; Government of Canada","keywords":"Autophagy; Mechanism (biology); Cell biology; Function (biology); Disease; Biology; Medicine; Neuroscience; Bioinformatics; Apoptosis; Pathology; Biochemistry","score_opus":0.016456976026479053,"score_gpt":0.31348225726003187,"score_spread":0.2970252812335528,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3096636232","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007517769,0.98943573,0.000116870455,0.00061330106,0.00028470033,0.0019452256,0.000055270513,0.000017229444,0.000013907556],"genre_scores_gemma":[0.00858579,0.98598343,0.0002246439,0.003805176,0.0010998861,0.00015731301,0.00006672145,0.00006185019,0.000015187474],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99806637,0.000093155366,0.0009027122,0.00044053682,0.0001588597,0.00033835042],"domain_scores_gemma":[0.99833053,0.00009880148,0.00033928422,0.00020125302,0.000054155174,0.0009759642],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021537402,0.00039278652,0.0023238282,0.0002822019,0.00006925288,0.00001803802,0.000108720924,0.00020325072,0.000025894431],"category_scores_gemma":[0.00002598848,0.00028507152,0.00036400353,0.00017752103,0.00006558594,0.000043533983,0.00004804888,0.00047071153,0.0000034866143],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010124644,0.00031651554,9.90042e-7,0.0069713704,0.0005804213,0.00005901992,0.00020790537,0.00001314966,0.002796021,0.00045869866,0.00039228814,0.97807896],"study_design_scores_gemma":[0.007492742,0.005113637,0.0009791217,0.0022935262,0.0006914502,0.00013848777,0.00006716914,0.0002207121,0.000041010488,0.007512815,0.9750558,0.00039354383],"about_ca_topic_score_codex":0.000005443983,"about_ca_topic_score_gemma":2.3653546e-7,"teacher_disagreement_score":0.97768545,"about_ca_system_score_codex":0.00011278518,"about_ca_system_score_gemma":0.0011832061,"threshold_uncertainty_score":0.9999601},"labels":[],"label_agreement":null},{"id":"W3096897243","doi":"10.3390/ijms21218051","title":"Recent Advances in Single-Particle Electron Microscopic Analysis of Autophagy Degradation Machinery","year":2020,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Vacuole; Autophagosome; Cell biology; Cytoplasm; Lysosome; Organelle; Biology; BAG3; Chemistry; Biochemistry","score_opus":0.029159553794686602,"score_gpt":0.38354035420072413,"score_spread":0.35438080040603753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3096897243","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.033181798,0.9657294,0.00037263962,0.0002368615,0.00024803638,0.00010670075,0.0000090447475,0.000003959996,0.00011154705],"genre_scores_gemma":[0.01579963,0.9834411,0.00050953706,0.00014579964,0.00006452121,0.0000025976954,0.000018630042,0.000008005965,0.000010174068],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979492,0.00012257123,0.0008274766,0.00018935234,0.0007827473,0.00012867159],"domain_scores_gemma":[0.9986366,0.000073505435,0.000890539,0.0000882728,0.00023132078,0.00007975901],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035142718,0.00014736754,0.0009060842,0.0007650127,0.000016331207,0.000032890537,0.00044118823,0.000059534632,0.00006647811],"category_scores_gemma":[0.00014548353,0.000107833555,0.0004925336,0.0012975773,0.00011024289,0.00017986345,0.00003156911,0.00019447383,0.0000020221064],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000529016,0.00022846644,0.00019884545,0.00017079113,0.0012454885,0.00033042292,0.00004528086,0.00016248842,0.002687247,0.00021740417,0.000004727882,0.9946559],"study_design_scores_gemma":[0.0015711391,0.0016263622,0.0008667219,0.0075419256,0.007348389,0.0004002753,0.00006395785,0.0010970003,0.039428562,0.0004976999,0.93915427,0.0004036855],"about_ca_topic_score_codex":0.0000034053069,"about_ca_topic_score_gemma":0.000004908884,"teacher_disagreement_score":0.99425226,"about_ca_system_score_codex":0.00016986964,"about_ca_system_score_gemma":0.0005643778,"threshold_uncertainty_score":0.4397325},"labels":[],"label_agreement":null},{"id":"W3098005452","doi":"10.1074/jbc.ra120.014415","title":"The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates","year":2020,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; University of Ottawa","keywords":"Cytosol; Cell biology; Autophagy; Chemistry; eIF2; Protein kinase A; Kinase; Biochemistry; Biology; Enzyme; Apoptosis; Translation (biology)","score_opus":0.02834064470669798,"score_gpt":0.2697052672104932,"score_spread":0.24136462250379523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3098005452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9743474,0.0142361885,0.000012232926,0.010682819,0.00002990942,0.00014657622,0.000004688919,0.000014067347,0.000526109],"genre_scores_gemma":[0.99729383,0.00096834294,0.000055389388,0.0010895786,0.00044852388,0.0000049674086,0.0000013034888,0.0000073222213,0.00013074628],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989709,0.000057473397,0.00044691912,0.00011372443,0.00023470339,0.00017625885],"domain_scores_gemma":[0.99892133,0.00015351047,0.00044935624,0.00017699231,0.00012134435,0.00017748529],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027339888,0.00012583862,0.0003222527,0.000006202331,0.000090188165,0.000013886934,0.00032317083,0.00011663979,0.00018195627],"category_scores_gemma":[0.0005550687,0.00005089164,0.0002975692,0.00014702653,0.00033313248,0.000025586342,0.000035127418,0.00044355102,0.000006589961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002888047,0.0002553656,0.0006104615,0.000121381745,0.00025704454,0.000262398,0.0001481069,0.0000058982073,0.9843391,0.000084966916,0.0006168233,0.010410397],"study_design_scores_gemma":[0.0014555943,0.00064845657,0.004068123,0.00014588668,0.00005923375,0.00013573721,0.0002521902,0.00007617347,0.97880244,0.0004777126,0.013792416,0.00008602458],"about_ca_topic_score_codex":6.4777015e-7,"about_ca_topic_score_gemma":1.9901496e-8,"teacher_disagreement_score":0.022946417,"about_ca_system_score_codex":0.000019989136,"about_ca_system_score_gemma":0.00010932256,"threshold_uncertainty_score":0.20753007},"labels":[],"label_agreement":null},{"id":"W3098934217","doi":"10.1080/15548627.2020.1848120","title":"AMPK-induced autophagy as a key regulator of cell migration","year":2020,"lang":"en","type":"letter","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Cell biology; AMPK; Cell migration; Regulator; BAG3; Cell; Focal adhesion; Signal transduction; Genetics; Gene; Phosphorylation; Protein kinase A","score_opus":0.017825699715311404,"score_gpt":0.2633998977220905,"score_spread":0.2455741980067791,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3098934217","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.49399275,0.0038108062,0.00008984922,0.4813899,0.0019778928,0.0024103054,0.00021957408,0.0008710567,0.0152378725],"genre_scores_gemma":[0.349589,0.00022483978,0.00061508303,0.6258218,0.005036018,0.000121852645,0.0012389211,0.0002717367,0.017080722],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99609923,0.00017899684,0.0010002659,0.0009807186,0.0010818957,0.00065891683],"domain_scores_gemma":[0.99728143,0.00015480546,0.0007140068,0.0012734905,0.00025614645,0.00032014376],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00011802219,0.00076406804,0.0014786286,0.0003413856,0.00010258617,0.000041839074,0.00045695496,0.0012931407,0.0020869814],"category_scores_gemma":[0.000113411166,0.0007170895,0.00078172743,0.00048997684,0.00015103132,0.00013588395,0.000103827864,0.0017117145,0.00104441],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003002549,0.00027992253,0.000028118102,0.0012469833,0.00054447935,0.004469876,0.0008010782,0.000001119511,0.14166802,0.00020687014,0.84878534,0.0016679618],"study_design_scores_gemma":[0.0023132516,0.0010359335,0.0011037801,0.00026642796,0.0006819315,0.00010924256,0.000029055669,0.00019604067,0.4875627,0.0012354325,0.50489426,0.00057198707],"about_ca_topic_score_codex":0.00019497405,"about_ca_topic_score_gemma":0.0000030088383,"teacher_disagreement_score":0.34589466,"about_ca_system_score_codex":0.00015911255,"about_ca_system_score_gemma":0.0009662989,"threshold_uncertainty_score":0.9997334},"labels":[],"label_agreement":null},{"id":"W3101257218","doi":"10.1242/bio.055103","title":"Assessing methods to quantitatively validate TGFβ-dependent autophagy","year":2020,"lang":"en","type":"article","venue":"Biology Open","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; ATG5; Autophagosome; Biology; Cell biology; Lysosome; Chloroquine; MG132; Transforming growth factor; Carcinogenesis; Cancer research; Proteasome inhibitor; Apoptosis; Proteasome; Cancer; Immunology; Biochemistry","score_opus":0.2499443056542117,"score_gpt":0.5435088391989015,"score_spread":0.2935645335446898,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3101257218","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85765547,0.0012224938,0.09611325,0.018628405,0.0005398736,0.001784093,0.00004327426,0.00022674726,0.0237864],"genre_scores_gemma":[0.8407862,0.000028820863,0.13246867,0.025551692,0.0002170914,0.00007128474,0.000051604744,0.000031735213,0.000792903],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986289,0.0003674019,0.0002470979,0.00042437905,0.000075004944,0.00025720146],"domain_scores_gemma":[0.9991627,0.0001260595,0.000077661316,0.00024177329,0.000062746236,0.00032907343],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004865526,0.00015401425,0.00042696088,0.000048409467,0.00009168185,0.00008340172,0.00038744195,0.000108307846,0.0008993694],"category_scores_gemma":[0.00027189712,0.00012219975,0.00007354201,0.00018940015,0.000059402246,0.00016528711,0.0003192258,0.00014729716,0.0004997318],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011552783,0.0002929144,0.006285591,0.000061963394,0.00067306607,0.0002820835,0.0019366484,0.0000100564075,0.831385,0.019440034,0.0049681393,0.13350923],"study_design_scores_gemma":[0.005997264,0.002713952,0.10907195,0.00011398065,0.00031685136,0.000059639744,0.0011634843,0.00064881006,0.586044,0.004379172,0.28874692,0.0007439382],"about_ca_topic_score_codex":0.00006509659,"about_ca_topic_score_gemma":0.0000012458198,"teacher_disagreement_score":0.2837788,"about_ca_system_score_codex":0.000025605927,"about_ca_system_score_gemma":0.00019857049,"threshold_uncertainty_score":0.9847464},"labels":[],"label_agreement":null},{"id":"W3101621601","doi":"10.1002/bies.202000212","title":"Fine‐tuning ER‐phagy by post‐translational modifications","year":2020,"lang":"en","type":"article","venue":"BioEssays","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Endoplasmic reticulum; Autophagy; Cell biology; Organelle; Homeostasis; Function (biology); Unfolded protein response; Biology; Chemistry; Biochemistry","score_opus":0.032872144411148115,"score_gpt":0.28312719873921427,"score_spread":0.25025505432806616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3101621601","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.80923104,0.0076465807,0.028718919,0.11287308,0.00027928432,0.0009264113,0.00081329927,0.0007086412,0.038802736],"genre_scores_gemma":[0.9944539,0.000031470376,0.0005909993,0.0037727938,0.00022704338,0.000017446708,0.00035934823,0.000018930015,0.00052804017],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99932116,0.000016617212,0.00015291903,0.00019135005,0.00017891862,0.00013904237],"domain_scores_gemma":[0.9995105,0.000033128046,0.000036413283,0.00015164808,0.000066413144,0.00020187469],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00003131335,0.00009861839,0.00012880252,0.000028151433,0.00008111728,0.000012632204,0.00007971563,0.000060962946,0.0010757413],"category_scores_gemma":[0.000031504787,0.000088765315,0.000078260906,0.0001426024,0.000046469788,0.00006142073,0.000009711231,0.00009845495,0.00023455336],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007402417,0.000766267,0.01151616,0.00017547217,0.0004571067,0.00009250514,0.0025468539,0.000049654514,0.75734586,0.035683304,0.16864271,0.021983892],"study_design_scores_gemma":[0.015354147,0.001527858,0.16169412,0.00021140811,0.0008256341,0.00005637085,0.0007907434,0.031528696,0.16097869,0.0047033,0.6207138,0.0016152603],"about_ca_topic_score_codex":0.00001436596,"about_ca_topic_score_gemma":0.0000012145017,"teacher_disagreement_score":0.5963671,"about_ca_system_score_codex":0.000010117309,"about_ca_system_score_gemma":0.00008408359,"threshold_uncertainty_score":0.9998374},"labels":[],"label_agreement":null},{"id":"W3103239306","doi":"10.21203/rs.3.rs-100397/v1","title":"ORF3a mediated-incomplete autophagy facilitates SARS-CoV-2 replication","year":2020,"lang":"en","type":"preprint","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"School of Medicine, Shanghai Jiao Tong University; Program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning; Science and Technology Commission of Shanghai Municipality; Fudan University; National Natural Science Foundation of China; Shanghai Municipal Health Commission; Shanghai Jiao Tong University; Shandong University","keywords":"Replication (statistics); Autophagy; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Virology; Viral replication; Cell biology; Coronavirus disease 2019 (COVID-19); Computer science; Biology; Computational biology; Genetics; Medicine; Virus","score_opus":0.08465523447946215,"score_gpt":0.3550859498088766,"score_spread":0.27043071532941443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3103239306","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9177939,0.003879107,0.0057653007,0.022293126,0.0009522794,0.0030213892,0.0006235113,0.0029754145,0.042695913],"genre_scores_gemma":[0.97945064,0.00055107474,0.0025431851,0.012502477,0.0005610299,0.00027605201,0.00238062,0.000093909424,0.0016410056],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971336,0.00008663171,0.000668612,0.0012481188,0.00050275575,0.00036028144],"domain_scores_gemma":[0.9972736,0.00012586707,0.00024719024,0.0019159414,0.00019406572,0.00024332471],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022089045,0.00048453355,0.00084317033,0.00015001983,0.00007349639,0.00004939341,0.00037713704,0.00044443493,0.0006439173],"category_scores_gemma":[0.00034448694,0.00041473316,0.0004121223,0.00019358388,0.00011660916,0.000057575206,0.00041458372,0.0007636218,0.0016833211],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015602737,0.0010864603,0.002202295,0.0033396685,0.0032811759,0.0008942711,0.0026411205,0.000027050339,0.7912151,0.008797839,0.15822013,0.026734626],"study_design_scores_gemma":[0.0041297697,0.00066883804,0.03541387,0.00057955313,0.0008517648,0.00007837678,0.00017211381,0.014437112,0.6873059,0.03966231,0.21517548,0.0015249011],"about_ca_topic_score_codex":0.00020605241,"about_ca_topic_score_gemma":0.0000065918557,"teacher_disagreement_score":0.10390918,"about_ca_system_score_codex":0.00014270387,"about_ca_system_score_gemma":0.00041899562,"threshold_uncertainty_score":0.9998304},"labels":[],"label_agreement":null},{"id":"W3104399624","doi":"10.1038/s41598-020-77347-w","title":"Single-cell analysis of autophagy activity in normal and de novo transformed human mammary cells","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Terry Fox Research Institute; BC Cancer Agency","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Autophagy; Autophagosome; Cell biology; Clonogenic assay; Biology; Cell; Cell culture; Carcinogenesis; Flux (metallurgy); Chemistry; Biochemistry; Gene; Apoptosis; Genetics","score_opus":0.019977226057644452,"score_gpt":0.2639248562245857,"score_spread":0.24394763016694127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3104399624","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970958,0.00018319197,0.0003300052,0.00015756377,0.00022605826,0.0002077138,0.0000037173022,0.000032372478,0.0017635786],"genre_scores_gemma":[0.9990993,0.000008054042,0.00019486867,0.00012002121,0.00002002575,0.000005300584,0.000028107304,0.000008804315,0.0005154965],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986252,0.00003566829,0.0003676671,0.00044200645,0.00030231386,0.00022712597],"domain_scores_gemma":[0.9991864,0.000019994906,0.00015668989,0.00036197912,0.00004765836,0.00022727092],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044926358,0.000110659865,0.00037062936,0.0003010309,0.00006825098,0.000036885285,0.00006140199,0.000067447276,0.00015544865],"category_scores_gemma":[0.000018697066,0.00010241551,0.0001603675,0.0010873477,0.00015644032,0.00013637771,0.000024921304,0.00010746804,0.0000012104267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000625686,0.000370454,0.017369732,0.00011476171,0.00014156917,0.0015105731,0.001368807,0.000042877786,0.97715086,0.000011119992,0.00012469623,0.0017319693],"study_design_scores_gemma":[0.00058060687,0.000115491086,0.06522988,0.000017451957,0.00039898686,0.00003243125,0.00004851401,0.0011453184,0.93156594,0.0001802143,0.00058351824,0.00010164175],"about_ca_topic_score_codex":0.000035927147,"about_ca_topic_score_gemma":0.000026614542,"teacher_disagreement_score":0.047860146,"about_ca_system_score_codex":0.00003739097,"about_ca_system_score_gemma":0.00016618418,"threshold_uncertainty_score":0.41763836},"labels":[],"label_agreement":null},{"id":"W3106260045","doi":"10.1158/1538-7445.panca20-po-044","title":"Abstract PO-044: ATG4B loss reduces pancreatic cancer cell viability and enhances the utilization of survival-promoting GABARAP-L2","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver General Hospital; BC Cancer Agency","funders":"","keywords":"Gene knockdown; Viability assay; Autophagy; Pancreatic cancer; Cell culture; Cancer research; Cancer cell; Cell growth; Cancer; Chemistry; Biology; Apoptosis; Medicine; Internal medicine; Biochemistry","score_opus":0.1335718949243083,"score_gpt":0.43370964650820965,"score_spread":0.3001377515839013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3106260045","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97655356,0.017713206,0.000011407434,0.00354995,0.00008017041,0.0006560627,0.000048063055,0.000027761535,0.0013598228],"genre_scores_gemma":[0.988738,0.010425104,0.000013038282,0.00013030785,0.00033404282,0.00013710867,0.000008865569,0.000023307943,0.00019024739],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998165,0.00021188772,0.00028227127,0.0003664617,0.0006360921,0.00033827944],"domain_scores_gemma":[0.99874866,0.00033564557,0.00009749704,0.00027537718,0.00033582223,0.00020702125],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00085948,0.00013156711,0.0003047574,0.000034270943,0.00018080173,0.000029704815,0.00018904786,0.00006985726,0.0013517227],"category_scores_gemma":[0.00021080973,0.00008842582,0.00006436798,0.00038955314,0.00045417016,0.00011433662,0.0000701175,0.00030684337,0.0000088317465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009989758,0.00021030116,0.0338148,0.0020083503,0.0001829806,0.000016716933,0.007347346,0.000016322205,0.9303869,0.00008168085,0.00065209024,0.02428354],"study_design_scores_gemma":[0.0007698384,0.00019860023,0.107315026,0.00027773314,0.00005196893,7.389428e-7,0.0014596715,0.00022050492,0.8884393,0.00020427938,0.0009566904,0.0001056281],"about_ca_topic_score_codex":0.0015003018,"about_ca_topic_score_gemma":0.00007969922,"teacher_disagreement_score":0.07350022,"about_ca_system_score_codex":0.00010258538,"about_ca_system_score_gemma":0.00047058394,"threshold_uncertainty_score":0.9995612},"labels":[],"label_agreement":null},{"id":"W3107348352","doi":"10.1371/journal.pone.0242695","title":"Enhanced mitophagy in bronchial fibroblasts from severe asthmatic patients","year":2020,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Christie (Canada)","funders":"University of Sharjah","keywords":"Mitophagy; Biology; PINK1; Mitochondrion; Parkin; Fibroblast; Fibrosis; Cell biology; Immunology; Medicine; Autophagy; Pathology; Cell culture; Apoptosis","score_opus":0.0252570164921236,"score_gpt":0.22055132332986144,"score_spread":0.19529430683773785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3107348352","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99759907,0.00022475893,0.000033491342,0.0005248025,0.000033805794,0.00041477737,0.000037340447,0.000070167705,0.001061772],"genre_scores_gemma":[0.9963956,0.000039672123,0.00091980054,0.002001673,0.00031442684,0.000026133164,0.0001588947,0.000025820682,0.00011801328],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989464,0.000034643435,0.00023921931,0.00024795946,0.0003366473,0.0001950848],"domain_scores_gemma":[0.9994677,0.000047113826,0.000058961155,0.00018340899,0.000040130762,0.00020273331],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000016763352,0.00013337047,0.00033754154,0.000035183828,0.000021433425,0.00000880923,0.00008331057,0.00007312457,0.0011110798],"category_scores_gemma":[0.00010079996,0.0001267485,0.000057730267,0.00014470323,0.000022283812,0.00008962973,0.000033233442,0.00016001542,0.00037751417],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007327147,0.024647076,0.18929982,0.0019970287,0.0025791593,0.00033444894,0.013843494,0.00003984255,0.740254,0.000100631,0.0023593784,0.017217964],"study_design_scores_gemma":[0.012871567,0.001446124,0.503764,0.0013052414,0.0002176082,4.651144e-7,0.00010023964,0.0013751048,0.47792882,0.00051146315,0.00008891527,0.0003905067],"about_ca_topic_score_codex":0.000020475924,"about_ca_topic_score_gemma":0.0000049947384,"teacher_disagreement_score":0.31446412,"about_ca_system_score_codex":0.000039802093,"about_ca_system_score_gemma":0.000050782746,"threshold_uncertainty_score":0.99980205},"labels":[],"label_agreement":null},{"id":"W3107656713","doi":"10.1139/cjpp-2020-0448","title":"FoxO3 transcription factor promotes autophagy after oxidative stress injury in HT22 cells","year":2020,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autophagy; FOXO3; Oxidative stress; Cell biology; Reactive oxygen species; Programmed cell death; Chemistry; Transcription factor; Gene knockdown; Downregulation and upregulation; Apoptosis; Biology; Signal transduction; Biochemistry; Protein kinase B","score_opus":0.01627124594798261,"score_gpt":0.28048530898432106,"score_spread":0.26421406303633843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3107656713","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99585944,0.0014902971,0.000011724158,0.0018960523,0.00041871963,0.00018495305,0.00010108936,0.000004790792,0.00003293334],"genre_scores_gemma":[0.99377096,0.00018820616,0.000033897373,0.0055711116,0.0003872579,0.000007865944,0.000007067489,0.000011196752,0.000022451371],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913627,0.00014922187,0.00026267927,0.0001514898,0.000045811837,0.00025450275],"domain_scores_gemma":[0.999143,0.000036622503,0.00010422886,0.00004352508,0.00006785938,0.00060478406],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000054787215,0.0001291838,0.00034954195,0.00015466164,0.000040643634,0.0000042734864,0.0000789779,0.00013297424,0.003889041],"category_scores_gemma":[0.0000099500485,0.00011110466,0.00007782912,0.00009438209,0.00017927377,0.00009830191,0.000005393284,0.00040222888,0.000009429947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011461006,0.000059351096,0.0020910338,0.00010453708,0.00015581358,0.0005456698,0.0024264539,0.000006633349,0.9917302,0.000020779808,0.0006367782,0.0010766118],"study_design_scores_gemma":[0.0021283831,0.0012949875,0.07731227,0.000034102643,0.00011454686,0.000033338445,0.00007962517,0.000079073,0.916095,0.00043228403,0.0022819252,0.00011443994],"about_ca_topic_score_codex":0.00011227178,"about_ca_topic_score_gemma":0.0001137728,"teacher_disagreement_score":0.07563521,"about_ca_system_score_codex":0.000044006898,"about_ca_system_score_gemma":0.0005288512,"threshold_uncertainty_score":0.99702156},"labels":[],"label_agreement":null},{"id":"W3108920207","doi":"10.1093/ibd/izaa305","title":"Salicylates Ameliorate Intestinal Inflammation by Activating Macrophage AMPK","year":2020,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa; McMaster University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Proinflammatory cytokine; Inflammation; AMPK; Tumor necrosis factor alpha; Autophagy; Myeloperoxidase; Medicine; Macrophage; Immunology; Inflammatory bowel disease; Protein kinase A; Kinase; Chemistry; Biology; Internal medicine; Cell biology; Biochemistry","score_opus":0.013353761043781045,"score_gpt":0.2576463380174055,"score_spread":0.24429257697362444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3108920207","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99433345,0.0016175846,0.00027131094,0.0016843466,0.000089807865,0.0005189009,0.00009802269,0.0006213275,0.0007652728],"genre_scores_gemma":[0.9960838,0.000093311544,0.00017934236,0.0023393617,0.00075289834,0.00008049972,0.0002273236,0.00007287704,0.00017060495],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998148,0.000090213754,0.00050290715,0.00044174783,0.00042725593,0.00038982418],"domain_scores_gemma":[0.99841017,0.000107105574,0.00024569756,0.0003234137,0.00014739919,0.00076623866],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000073690586,0.00034239382,0.00034356542,0.000083629966,0.00017586,0.00008830814,0.00018530483,0.000104518964,0.00072421815],"category_scores_gemma":[0.00048001143,0.00031898828,0.00019763876,0.00026442995,0.0001540841,0.00040296698,0.00007670412,0.00026175537,0.00038816826],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0042807288,0.00049438915,0.31239143,0.0016758926,0.00066227093,0.0025866195,0.0021003268,0.00023384087,0.59551805,0.0008741962,0.031778477,0.047403753],"study_design_scores_gemma":[0.0070935856,0.00078034773,0.6379338,0.00077029,0.0005527094,0.00006123661,0.0008701895,0.006924418,0.3041259,0.001312784,0.03814063,0.0014341172],"about_ca_topic_score_codex":0.000008118501,"about_ca_topic_score_gemma":4.771194e-7,"teacher_disagreement_score":0.32554236,"about_ca_system_score_codex":0.000072419614,"about_ca_system_score_gemma":0.00021594063,"threshold_uncertainty_score":0.9999262},"labels":[],"label_agreement":null},{"id":"W3108936441","doi":"10.1080/15548627.2020.1797280","title":"Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>","year":2021,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2629,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; Université de Moncton; York University; University of Guelph; Concordia University; Libin Cardiovascular Institute of Alberta; University of Prince Edward Island; Ottawa Hospital; Université du Québec à Montréal; Université de Sherbrooke; University of Waterloo; University of Ottawa; Dalhousie University; Canada's Michael Smith Genome Sciences Centre; University of Alberta; Queen's University; Montreal Neurological Institute and Hospital; Sinai Health System; University of British Columbia; SickKids Foundation; Research Institute in Oncology and Hematology; University of Calgary; Spinal Cord Injury BC; University of Manitoba; CancerCare Manitoba; Lunenfeld-Tanenbaum Research Institute; McGill University; Université du Québec à Trois-Rivières; McGill University Health Centre; St. Boniface Hospital; Université de Montréal; Centre for Addiction and Mental Health; Institut National de la Recherche Scientifique; University of Victoria; Hospital for Sick Children; Western University; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Dental and Craniofacial Research; National Institute of Environmental Health Sciences; Francis Crick Institute; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; Cancer Research UK; Wellcome Trust; Biotechnology and Biological Sciences Research Council; National Institute on Alcohol Abuse and Alcoholism; National Eye Institute; National Institute on Aging; LEO Fondet; National Institute of Allergy and Infectious Diseases; Agence Nationale de la Recherche; Lundbeckfonden; Novo Nordisk Fonden; Rosetrees Trust; Medical Research Council; Kennedy Trust for Rheumatology Research; Psoriasis Association; National Cancer Institute; National Institute of Neurological Disorders and Stroke; British Heart Foundation; European Hematology Association; U.S. Department of Veterans Affairs","keywords":"Autophagy; Biology; Interpretation (philosophy); Computational biology; Biochemistry; Computer science; Apoptosis; Programming language","score_opus":0.08836721107916955,"score_gpt":0.36219591246702554,"score_spread":0.273828701387856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3108936441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8351784,0.012920422,0.14366768,0.0040859506,0.001428724,0.0020656227,0.0002986913,0.00019183864,0.00016272416],"genre_scores_gemma":[0.9784307,0.0005989814,0.015842939,0.0013843357,0.001309903,0.00034589873,0.00013108835,0.000050431554,0.0019057288],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987261,0.0000402544,0.00047077087,0.00030675047,0.00021682329,0.00023927145],"domain_scores_gemma":[0.9973943,0.0009808483,0.00014637891,0.0003743612,0.0010078746,0.00009619549],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000272239,0.00018149747,0.00034768262,0.00006853258,0.00015564731,0.000050782437,0.000095203104,0.00011142657,0.000062241146],"category_scores_gemma":[0.0013582923,0.00013653877,0.0002185914,0.00014028088,0.000085049986,0.0002292548,0.000040639174,0.00009389092,0.000002937205],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004749265,0.0016548478,0.007552385,0.0031176645,0.0047655418,0.00019287074,0.008453513,0.009187993,0.116783455,0.03041393,0.084788755,0.7283398],"study_design_scores_gemma":[0.008392184,0.0008295345,0.031876728,0.000675367,0.0012348101,0.00012934528,0.0013356636,0.40789506,0.48028708,0.006198349,0.060686007,0.00045986997],"about_ca_topic_score_codex":0.000020676543,"about_ca_topic_score_gemma":0.0000014367874,"teacher_disagreement_score":0.7278799,"about_ca_system_score_codex":0.000036745958,"about_ca_system_score_gemma":0.00017794894,"threshold_uncertainty_score":0.556789},"labels":[],"label_agreement":null},{"id":"W3109271117","doi":"10.20892/j.issn.2095-3941.2020.0005","title":"Adaptive response of resistant cancer cells to chemotherapy","year":2020,"lang":"en","type":"review","venue":"Cancer Biology and Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Autophagy; Context (archaeology); Cancer; Mechanism (biology); Cancer cell; Adaptive response; Chemotherapy; Cancer therapy; Endoplasmic reticulum; Biology; Cancer research; Medicine; Bioinformatics; Internal medicine; Apoptosis; Cell biology","score_opus":0.06049247437061154,"score_gpt":0.43054180148300675,"score_spread":0.3700493271123952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3109271117","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00049079646,0.99446714,0.00002943247,0.0030581444,0.00044015946,0.0010159807,0.00030361023,0.000028493654,0.00016626254],"genre_scores_gemma":[0.00039332948,0.99332047,0.00006133593,0.0042158575,0.0009002257,0.00029030655,0.00003748899,0.000045924593,0.0007350672],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983993,0.00020455931,0.00052663824,0.00050190696,0.00011309983,0.0002544959],"domain_scores_gemma":[0.99868125,0.00026107728,0.00028327722,0.00030632425,0.00009544226,0.00037263555],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026383725,0.0003775274,0.002491949,0.00017918134,0.000040974144,0.0000011062752,0.00013577644,0.0003577349,0.00081127865],"category_scores_gemma":[0.00007772895,0.0002342088,0.00017936288,0.00034462736,0.00043239573,0.0000102176755,0.000037081765,0.000307708,0.000008686132],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008010625,0.000039217448,0.000012543711,0.004178982,0.0010409799,0.00007079684,0.00049715437,5.6248176e-8,0.0031861062,0.0001584607,0.006742157,0.9760629],"study_design_scores_gemma":[0.0015037709,0.0019711268,0.000122074,0.01595425,0.001412355,0.000011361572,0.00005212792,7.4624796e-7,0.0006819991,0.000050714236,0.9780447,0.00019475479],"about_ca_topic_score_codex":0.00013835364,"about_ca_topic_score_gemma":0.000007522924,"teacher_disagreement_score":0.97586817,"about_ca_system_score_codex":0.00012265897,"about_ca_system_score_gemma":0.0009475448,"threshold_uncertainty_score":0.95507574},"labels":[],"label_agreement":null},{"id":"W3109443217","doi":"10.1152/ajplung.00122.2020","title":"The aryl hydrocarbon receptor reduces LC3II expression and controls endoplasmic reticulum stress","year":2020,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; McGill University Health Centre; Institute of Health Services and Policy Research; Government of Canada; McGill University","keywords":"Autophagy; Unfolded protein response; Aryl hydrocarbon receptor; ATG5; Endoplasmic reticulum; Cell biology; Downregulation and upregulation; Chemistry; Apoptosis; Transcription factor; Biology; Biochemistry","score_opus":0.003802307103396914,"score_gpt":0.22429930297836392,"score_spread":0.22049699587496702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3109443217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98802555,0.009319604,0.0000984983,0.0021068584,0.00014561736,0.00022575354,0.000008142824,0.000018350654,0.000051636085],"genre_scores_gemma":[0.9943746,0.002960724,0.00019439402,0.0020347594,0.0003664705,0.000009674802,0.000018328263,0.00003111184,0.0000099605495],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983821,0.00030054394,0.00043754556,0.00035766055,0.00017436974,0.00034780975],"domain_scores_gemma":[0.99861443,0.00018913987,0.00050653284,0.00023300342,0.00010695456,0.00034992286],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013351998,0.00026471054,0.0007755987,0.00005372157,0.00016095956,0.000016232083,0.00018744775,0.00008966949,0.000023367833],"category_scores_gemma":[0.00009486197,0.00016990805,0.00020954886,0.00012718009,0.0009894918,0.000057174362,0.0000911062,0.00043431536,0.0000032374517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018349217,0.00007799985,0.000092780814,0.00003997071,0.00036590104,0.000049662194,0.00030964278,0.000020679568,0.9952313,0.00011050094,0.0002542149,0.001612484],"study_design_scores_gemma":[0.0021765023,0.0029591168,0.004113161,0.000106677624,0.00025042958,0.00007827973,0.00075451675,0.0005708061,0.98711944,0.0004792806,0.0011900185,0.00020178946],"about_ca_topic_score_codex":0.000006928394,"about_ca_topic_score_gemma":1.08540114e-7,"teacher_disagreement_score":0.008111821,"about_ca_system_score_codex":0.00001358278,"about_ca_system_score_gemma":0.00008942932,"threshold_uncertainty_score":0.6928649},"labels":[],"label_agreement":null},{"id":"W3110102984","doi":"10.3390/ijms21239033","title":"Foam Cell Induction Activates AMPK But Uncouples Its Regulation of Autophagy and Lysosomal Homeostasis","year":2020,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Canadian Institutes of Health Research; National Health and Medical Research Council; Ontario Ministry of Research, Innovation and Science; Canada Research Chairs","keywords":"AMPK; Cell biology; Autophagy; AMP-activated protein kinase; Foam cell; CD36; Signal transduction; Protein kinase A; Lipid metabolism; Downregulation and upregulation; Transcription factor; Chemistry; Cell signaling; Biology; Phosphorylation; Macrophage; Biochemistry; Apoptosis","score_opus":0.024211398335905233,"score_gpt":0.289412932236547,"score_spread":0.2652015339006418,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3110102984","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932221,0.0023207148,0.001071766,0.0028626877,0.0002129789,0.00005848486,0.000005169918,0.000006654649,0.00023941502],"genre_scores_gemma":[0.9980137,0.0003173301,0.001058975,0.00041649875,0.0001697224,6.317033e-7,0.0000020380287,0.0000050995395,0.000016043581],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99879944,0.000030804982,0.00028696604,0.00012091717,0.0006847802,0.00007709447],"domain_scores_gemma":[0.9991181,0.00003579324,0.0003395239,0.000041228974,0.0003606063,0.00010475863],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017135515,0.000075461496,0.00015715181,0.00016102244,0.00003568647,0.000032420154,0.00017822118,0.000038582504,0.00007410297],"category_scores_gemma":[0.0001077856,0.0000593618,0.000086761975,0.00017135774,0.00013689548,0.00027738756,0.000031797805,0.00008841725,0.0000017141518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022704841,0.00008415861,0.0013782706,0.00001825162,0.00011258561,0.000071907896,0.00034783545,0.00034659024,0.98653245,0.0005584392,0.00004005462,0.010282408],"study_design_scores_gemma":[0.0008223669,0.0005093251,0.028253017,0.00006580366,0.00004525608,0.00012415778,0.00034271547,0.0011762144,0.9676667,0.0007718215,0.00016582967,0.00005682394],"about_ca_topic_score_codex":0.000006035154,"about_ca_topic_score_gemma":1.8691338e-7,"teacher_disagreement_score":0.026874747,"about_ca_system_score_codex":0.00002320961,"about_ca_system_score_gemma":0.0001609175,"threshold_uncertainty_score":0.24207039},"labels":[],"label_agreement":null},{"id":"W3110773542","doi":"10.1016/j.exger.2020.111190","title":"Purple Sweet Potato Extract extends lifespan by activating autophagy pathway in male Drosophila melanogaster","year":2020,"lang":"en","type":"article","venue":"Experimental Gerontology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"Tianjin Science and Technology Program; Natural Science Foundation of Tianjin City","keywords":"Drosophila melanogaster; Biology; Autophagy; Superoxide dismutase; Catalase; PI3K/AKT/mTOR pathway; Cell biology; Oxidative stress; Signal transduction; Biochemistry; Gene; Apoptosis","score_opus":0.036163909887405254,"score_gpt":0.31623687230866154,"score_spread":0.2800729624212563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3110773542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98274887,0.0062572807,0.00009609964,0.002310237,0.00020457372,0.0004039493,0.000021876956,0.00011937569,0.007837769],"genre_scores_gemma":[0.9931784,0.000018256153,0.00048054798,0.004821704,0.00028337314,0.00011719316,0.00008980781,0.00005408531,0.0009566173],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981656,0.000095179304,0.00042420585,0.0005595402,0.00023095697,0.0005245125],"domain_scores_gemma":[0.99917835,0.00004265437,0.00012154894,0.00027693552,0.00001760399,0.00036292427],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007483567,0.00030448768,0.0005420453,0.00007001656,0.000072557574,0.000018922574,0.00017121015,0.00019456753,0.0035327745],"category_scores_gemma":[0.00003300927,0.00029302674,0.00013434672,0.00014158341,0.00011347675,0.00018213848,0.0000832012,0.00030190565,0.00017434928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010309984,0.0010225032,0.0028781178,0.000029451128,0.0000977789,0.001071659,0.0047304872,0.0000023393231,0.97992027,0.00042074142,0.0048533706,0.0039422777],"study_design_scores_gemma":[0.0050092135,0.001592202,0.006280339,0.000040808365,0.000014105717,0.00031615447,0.0020069836,0.00045957486,0.965193,0.000051946565,0.018667253,0.00036843645],"about_ca_topic_score_codex":0.00006621427,"about_ca_topic_score_gemma":0.0000049576656,"teacher_disagreement_score":0.014727293,"about_ca_system_score_codex":0.000129741,"about_ca_system_score_gemma":0.00008100346,"threshold_uncertainty_score":0.9999522},"labels":[],"label_agreement":null},{"id":"W3111685565","doi":"10.1016/j.bbamcr.2020.118926","title":"Autophagy and the Wnt signaling pathway: A focus on Wnt/β-catenin signaling","year":2020,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":179,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; University of Manitoba; Research Institute in Oncology and Hematology","funders":"","keywords":"Autophagy; Wnt signaling pathway; Cell biology; Crosstalk; Dishevelled; Signal transduction; LRP6; ULK1; LRP5; Biology; Phosphorylation; Frizzled; Chemistry; Protein kinase A; Biochemistry; Apoptosis; AMPK","score_opus":0.06760125101746188,"score_gpt":0.37305884853974125,"score_spread":0.30545759752227936,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3111685565","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.034770418,0.95550185,0.000034972083,0.0026495866,0.00012375998,0.0042735008,0.00011032991,0.00019098519,0.0023445783],"genre_scores_gemma":[0.29976213,0.6976244,0.00012598558,0.0006243414,0.0005374637,0.00048493664,0.00021995824,0.000304313,0.00031647002],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99087876,0.002688098,0.00109403,0.0018290101,0.0021746294,0.001335494],"domain_scores_gemma":[0.99556786,0.0015632691,0.00049318554,0.0012374173,0.00030024577,0.00083803874],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0018318415,0.0011908828,0.0029243766,0.0006268844,0.0005097886,0.00037557338,0.0011483814,0.0006978106,0.00009627599],"category_scores_gemma":[0.00029416126,0.00078390667,0.0016552274,0.0015574133,0.00102423,0.00007736433,0.000701513,0.0033567634,0.00037554227],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022600912,0.0013126658,2.8625665e-8,0.014164854,0.0028352179,0.0035575,0.001152823,0.0000024441945,0.6921326,0.006590045,0.00066212734,0.27532962],"study_design_scores_gemma":[0.0035079657,0.0012674009,7.484713e-7,0.0074329376,0.0015421147,0.000058428664,0.00010125066,0.00011358192,0.88860214,0.0019887667,0.09440494,0.0009797468],"about_ca_topic_score_codex":0.000055513898,"about_ca_topic_score_gemma":3.646942e-7,"teacher_disagreement_score":0.2743499,"about_ca_system_score_codex":0.0002561573,"about_ca_system_score_gemma":0.0019255773,"threshold_uncertainty_score":0.9994612},"labels":[],"label_agreement":null},{"id":"W3112028947","doi":"10.1016/j.bbamcr.2020.118924","title":"Heat shock increases levels of reactive oxygen species, autophagy and apoptosis","year":2020,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Apoptosis; Cell biology; Reactive oxygen species; Heat shock protein; Heat shock; ATG5; Programmed cell death; Hsp70; Chemistry; Endoplasmic reticulum; Biology; Biochemistry","score_opus":0.060422169378256944,"score_gpt":0.3311421285382644,"score_spread":0.27071995916000746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112028947","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9879449,0.00093472056,0.000045053363,0.00431677,0.000029664163,0.0008510806,0.00020333215,0.000076154334,0.005598341],"genre_scores_gemma":[0.9968439,0.00071900885,0.0003925211,0.0013021255,0.00018325762,0.000042912412,0.000119013195,0.00008671236,0.00031057495],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99647254,0.0004604323,0.0004199481,0.00082315423,0.0011712116,0.000652715],"domain_scores_gemma":[0.9978683,0.0002751383,0.000077873876,0.00070835,0.00035185102,0.0007185105],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003555801,0.00036595436,0.00066739856,0.00026007462,0.00016206654,0.000066919005,0.00039484724,0.00020280194,0.00023316061],"category_scores_gemma":[0.00021713498,0.00033055365,0.0002824614,0.0008715378,0.000585687,0.00012500749,0.0003993429,0.0006487609,0.00004536052],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00095798145,0.00069114234,0.000010109436,0.00029662903,0.00030992087,0.00009399178,0.00064321235,7.794927e-7,0.9950311,0.00033181455,0.0012428549,0.0003904189],"study_design_scores_gemma":[0.0016349624,0.0011980764,0.006579456,0.000102659804,0.00013574697,0.000005864531,0.000325215,0.00021471249,0.98834074,0.00021294714,0.0009699472,0.00027966112],"about_ca_topic_score_codex":0.00014990583,"about_ca_topic_score_gemma":6.2635246e-7,"teacher_disagreement_score":0.00889899,"about_ca_system_score_codex":0.00008727927,"about_ca_system_score_gemma":0.00052569626,"threshold_uncertainty_score":0.99991465},"labels":[],"label_agreement":null},{"id":"W3112306981","doi":"10.1016/j.dnarep.2020.103032","title":"DNA damage response and breast cancer development: Possible therapeutic applications of ATR, ATM, PARP, BRCA1 inhibition","year":2020,"lang":"en","type":"review","venue":"DNA repair","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acadia University","funders":"Tabriz University of Medical Sciences","keywords":"DNA damage; Autophagy; Breast cancer; Biology; DNA repair; Cancer; Cancer research; Senescence; Poly ADP ribose polymerase; Cancer cell; Apoptosis; DNA; Cell biology; Genetics","score_opus":0.028432925671435905,"score_gpt":0.33254318362458696,"score_spread":0.30411025795315105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112306981","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004180523,0.9931889,0.000039238028,0.00030326852,0.000040572373,0.001526303,0.00027595373,0.00021307389,0.00023213493],"genre_scores_gemma":[0.0016240319,0.99545383,0.00025505526,0.00039791985,0.00016059086,0.0007861398,0.0003039474,0.00007827076,0.0009401925],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982087,0.00018822822,0.00062288606,0.00048959383,0.0002637411,0.00022682623],"domain_scores_gemma":[0.9986902,0.00015546744,0.0003455445,0.0004912146,0.00009464183,0.00022291981],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026835428,0.00035754842,0.0011319706,0.00016174278,0.00010817262,0.000014503336,0.00010111401,0.00024287138,0.00027646637],"category_scores_gemma":[0.00001876291,0.00028812874,0.0003590171,0.0004890062,0.0001251241,0.00005868653,0.000062984676,0.0002509848,0.00005240683],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046772143,0.00021318419,0.00011693869,0.011263064,0.0009800208,0.00007605809,0.00037954337,4.8662613e-8,0.00015368279,0.00012008055,0.0006570579,0.9855726],"study_design_scores_gemma":[0.00064951903,0.00007229391,0.0036186294,0.005719533,0.0011302587,0.00012242168,0.000037440015,0.0000057506545,0.000186244,0.00004483286,0.988146,0.00026709933],"about_ca_topic_score_codex":0.000014937024,"about_ca_topic_score_gemma":0.0000033516646,"teacher_disagreement_score":0.9874889,"about_ca_system_score_codex":0.0001668527,"about_ca_system_score_gemma":0.0013088768,"threshold_uncertainty_score":0.9999571},"labels":[],"label_agreement":null},{"id":"W3112438754","doi":"10.21873/anticanres.14689","title":"Mir-139 Regulates Autophagy in Prostate Cancer Cells Through Beclin-1 and mTOR Signaling Proteins","year":2020,"lang":"en","type":"article","venue":"Anticancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"DU145; Autophagy; LNCaP; PI3K/AKT/mTOR pathway; Prostate cancer; Cancer research; Cell biology; Downregulation and upregulation; Cancer cell; Transfection; Chemistry; Apoptosis; Biology; Cancer; Signal transduction; Cell culture; Biochemistry","score_opus":0.09802302110117059,"score_gpt":0.4163388469080242,"score_spread":0.3183158258068536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112438754","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97701573,0.0072107604,0.00001408032,0.013656951,0.000052727577,0.001454476,0.000027257784,0.00006116327,0.00050683983],"genre_scores_gemma":[0.99363536,0.0029348435,0.00056832994,0.0015370818,0.0003497464,0.0002606833,0.000007643985,0.000046877696,0.00065943337],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976992,0.00014887271,0.00030697408,0.00054608134,0.00065081497,0.0006480767],"domain_scores_gemma":[0.9990567,0.00013658681,0.000046202684,0.0002965343,0.00017781461,0.0002861887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043312524,0.00017562322,0.00037434755,0.000102041384,0.00013484132,0.00005394679,0.00018214277,0.00008574827,0.0006932172],"category_scores_gemma":[0.00012734551,0.00014694274,0.000060206068,0.000648751,0.0003458712,0.00016003444,0.00015431238,0.00056874496,0.000057853806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026933874,0.00039187187,0.018270882,0.0011680003,0.0002334364,0.0009632369,0.009533753,0.000049307546,0.95210344,0.00069146144,0.0033981309,0.010503068],"study_design_scores_gemma":[0.0031531255,0.00068857527,0.016683146,0.00054453197,0.000036274807,0.0000055845153,0.0005857293,0.0021011208,0.96545047,0.0017602962,0.008743921,0.00024722237],"about_ca_topic_score_codex":0.0012174665,"about_ca_topic_score_gemma":0.000045381035,"teacher_disagreement_score":0.016619615,"about_ca_system_score_codex":0.00010605844,"about_ca_system_score_gemma":0.0005183096,"threshold_uncertainty_score":0.75902426},"labels":[],"label_agreement":null},{"id":"W3115531663","doi":"10.3390/biology9120481","title":"Mitophagy: A New Player in Stem Cell Biology","year":2020,"lang":"en","type":"review","venue":"Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Mitophagy; Biology; Stem cell; Cell biology; Mitochondrion; Organelle; Cellular differentiation; Cell; Autophagy; Genetics; Apoptosis","score_opus":0.07242213483800103,"score_gpt":0.3784042369621227,"score_spread":0.3059821021241217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3115531663","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001471651,0.99612784,0.00001793948,0.00013009546,0.00055793364,0.000780833,0.000065903296,0.0000729193,0.0020993426],"genre_scores_gemma":[0.00019675371,0.9959736,0.00008871629,0.0008174465,0.0010060229,0.00007534511,0.0003668096,0.000055160228,0.0014201433],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99810684,0.0002583661,0.0005861677,0.00060651905,0.00004375245,0.00039837355],"domain_scores_gemma":[0.9989323,0.00016841797,0.00021663049,0.00040191493,0.000015060401,0.0002656915],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008002284,0.00042075076,0.002353588,0.00021944214,0.000018182414,0.0000043130512,0.00025388872,0.0009350502,0.00051872566],"category_scores_gemma":[0.000017584292,0.0002987643,0.00047080222,0.00029255683,0.00007871286,0.0000120141785,0.00008826544,0.00052078476,0.0010191874],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050104238,0.00007592569,0.000081994964,0.0021989183,0.00017645484,0.00024233221,0.000037614216,1.1229198e-8,0.000037428337,0.00033655798,0.0019019261,0.9948607],"study_design_scores_gemma":[0.00092451915,0.00039792518,0.000020543286,0.0010273685,0.00028888826,0.000052287432,0.0000055490714,8.6608446e-7,0.00004536637,0.0001926517,0.9968061,0.00023796986],"about_ca_topic_score_codex":0.00004659952,"about_ca_topic_score_gemma":0.0000038308126,"teacher_disagreement_score":0.99490416,"about_ca_system_score_codex":0.0000976956,"about_ca_system_score_gemma":0.0009775743,"threshold_uncertainty_score":0.9999465},"labels":[],"label_agreement":null},{"id":"W3118783857","doi":"10.1101/2021.01.06.425538","title":"A syntenin-deficient microenvironment educates AML for aggressiveness","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"Vlaamse regering; Université François-Rabelais; Institut National Du Cancer; Université de Liège; KU Leuven; Fonds Wetenschappelijk Onderzoek; Institut National de la Santé et de la Recherche Médicale; Fondation contre le Cancer; Agence Nationale de la Recherche","keywords":"Stromal cell; Autophagy; Crosstalk; Tumor microenvironment; Cancer research; Stroma; Biology; Myeloid leukemia; Cell biology; Immunology; Apoptosis; Tumor cells; Genetics","score_opus":0.013133632774599948,"score_gpt":0.24323704332575197,"score_spread":0.23010341055115202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3118783857","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97487634,0.018956337,0.0015452029,0.0006535145,0.0016630102,0.00174971,0.0003205197,0.00023063766,0.0000047373806],"genre_scores_gemma":[0.9906717,0.0015569327,0.004675802,0.0008989021,0.00074480945,0.0012056484,0.000004748263,0.00021143972,0.000030036928],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969157,0.00008332601,0.0005790912,0.001282289,0.00043594162,0.00070363836],"domain_scores_gemma":[0.99693966,0.00008551825,0.00045065876,0.0016501583,0.0004009315,0.00047305017],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029345084,0.0006770371,0.00094147236,0.00021366103,0.00018587855,0.0001669983,0.00037667,0.00049358804,0.00021578043],"category_scores_gemma":[0.00016796871,0.0006777591,0.0005259832,0.00023059217,0.00016492579,0.000069093476,0.00037339513,0.00055879285,0.000050554518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002793525,0.0014239656,0.007255124,0.002003675,0.0009131917,0.00039275238,0.00003332878,0.00005020872,0.98688954,0.00010779102,0.00063975266,0.00001129605],"study_design_scores_gemma":[0.0017008643,0.00015591066,0.122469455,0.0022833752,0.0008802269,1.6242315e-7,0.000025321608,0.0001681109,0.8626657,0.0000024325025,0.00880666,0.0008417681],"about_ca_topic_score_codex":0.00001715405,"about_ca_topic_score_gemma":3.8743167e-7,"teacher_disagreement_score":0.12422385,"about_ca_system_score_codex":0.00046909545,"about_ca_system_score_gemma":0.0012688722,"threshold_uncertainty_score":0.9995674},"labels":[],"label_agreement":null},{"id":"W3119003533","doi":"10.1016/j.bbrc.2020.12.091","title":"The papain-like protease of coronaviruses cleaves ULK1 to disrupt host autophagy","year":2021,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Mitacs; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada; ALS Society of Canada; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Biology; ULK1; Coronavirus; Proteases; Protein kinase domain; Virology; Cell biology; Betacoronavirus; Viral replication; Viral pathogenesis; Protein kinase A; Kinase; Virus; Genetics; Mutant; Medicine; Coronavirus disease 2019 (COVID-19); Gene; Biochemistry; Enzyme","score_opus":0.09408823627924245,"score_gpt":0.42627619234959846,"score_spread":0.332187956070356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3119003533","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97877026,0.004781115,0.000013627006,0.015017115,0.000018540348,0.0005010632,0.000051068524,0.000030256158,0.00081697246],"genre_scores_gemma":[0.9957818,0.0020394141,0.0006340203,0.00046246982,0.00007762699,0.00015490578,0.00004142938,0.000013477981,0.0007948897],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984924,0.00025279276,0.00023369236,0.00024230588,0.0004686098,0.00031018775],"domain_scores_gemma":[0.9966202,0.0010384537,0.00003345987,0.0014383319,0.0004886489,0.00038094772],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032146007,0.0001075792,0.00020455837,0.000039912273,0.00043162866,0.000045062072,0.0004733014,0.000071417875,0.000030418925],"category_scores_gemma":[0.0009233483,0.00007043763,0.00010679042,0.0005430758,0.0012246189,0.00003315598,0.00060318987,0.00039932263,0.000040022005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002448192,0.00093993015,0.0002367411,0.00005122826,0.00006781056,0.0000087492035,0.00013019251,1.9915955e-8,0.9783904,0.009420523,0.0019376929,0.008571886],"study_design_scores_gemma":[0.00059279165,0.00034299353,0.037115782,0.00016015748,0.000039621274,0.000009593488,0.0004357005,0.00012742983,0.9158313,0.0020180035,0.043197285,0.00012931056],"about_ca_topic_score_codex":0.000051811887,"about_ca_topic_score_gemma":0.000005118513,"teacher_disagreement_score":0.062559076,"about_ca_system_score_codex":0.000035125904,"about_ca_system_score_gemma":0.00026619824,"threshold_uncertainty_score":0.45121592},"labels":[],"label_agreement":null},{"id":"W3119997908","doi":"10.3390/cancers13020181","title":"Crizotinib Resistance Mediated by Autophagy Is Higher in the Stem-Like Cell Subset in ALK-Positive Anaplastic Large Cell Lymphoma, and This Effect Is MYC-Dependent","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Autophagy; Crizotinib; Cancer research; Chemistry; Stem cell; Biology; Cell biology; Medicine; Apoptosis; Internal medicine; Biochemistry","score_opus":0.006212101999868864,"score_gpt":0.2425711424450654,"score_spread":0.23635904044519654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3119997908","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.958393,0.031663395,0.000006576284,0.00062792824,0.00034711018,0.0005348996,0.0006059447,0.000033259737,0.007787892],"genre_scores_gemma":[0.9763326,0.0016713025,0.000009632003,0.008533884,0.00006176844,0.000097657,0.000106046245,0.000038866947,0.013148219],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979767,0.00028429058,0.00031164405,0.00054306036,0.0004097083,0.00047458778],"domain_scores_gemma":[0.9988499,0.00042364906,0.00010599367,0.00039962571,0.000058421698,0.00016238667],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00028979304,0.00028314555,0.00045070625,0.00009050423,0.00008089092,0.000034117747,0.00015645457,0.00016490465,0.0009628067],"category_scores_gemma":[0.000017586774,0.00022182541,0.00008838336,0.0004668336,0.00008870563,0.00008269691,0.000037792655,0.00023656088,0.00004275769],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010881698,0.0028776797,0.061482556,0.003214857,0.00087587023,0.014728745,0.043648925,0.00003073666,0.08758093,0.00027355095,0.7710586,0.003345827],"study_design_scores_gemma":[0.05570268,0.0012482689,0.087415636,0.0010577978,0.00056375365,0.00003533381,0.0027403056,0.0006810455,0.71098894,0.00010947418,0.13828163,0.0011751348],"about_ca_topic_score_codex":0.0002493183,"about_ca_topic_score_gemma":0.00040555937,"teacher_disagreement_score":0.632777,"about_ca_system_score_codex":0.0007062872,"about_ca_system_score_gemma":0.0005357822,"threshold_uncertainty_score":0.99995047},"labels":[],"label_agreement":null},{"id":"W3120767348","doi":"10.1111/obr.13164","title":"The lifecycle of skeletal muscle mitochondria in obesity","year":2021,"lang":"en","type":"review","venue":"Obesity Reviews","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Skeletal muscle; mitochondrial fusion; Mitochondrion; Cell biology; Mitochondrial biogenesis; Biology; Function (biology); Mitochondrial fission; Endocrinology; Internal medicine; Autophagy; Medicine; Biochemistry; Mitochondrial DNA; Gene","score_opus":0.047837465595717325,"score_gpt":0.3623186851525864,"score_spread":0.3144812195568691,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3120767348","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002482809,0.9956273,0.000006548042,0.00003558369,0.00034427352,0.002354179,0.000021246584,0.000021014588,0.0013416102],"genre_scores_gemma":[0.000010858181,0.997354,0.00015038952,0.000113760514,0.00030936435,0.00018381189,0.00011291159,0.00004530524,0.0017196372],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99663997,0.00083801645,0.0013606694,0.00048601552,0.0003161547,0.00035918914],"domain_scores_gemma":[0.9974444,0.00027524136,0.0006641247,0.0013654954,0.00007566641,0.00017505368],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009474073,0.00045904107,0.00388643,0.00009042014,0.00010525685,0.000023909332,0.0004134948,0.00031219207,0.0003471855],"category_scores_gemma":[0.00042080166,0.00027437293,0.001855367,0.00063591753,0.0001259135,0.00005053343,0.00014140565,0.0006407517,0.0003473452],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000247665,0.0004452658,0.00009009852,0.020422915,0.00012400202,0.00006991266,0.00002685422,1.3990494e-8,0.0000017338621,0.0001925788,0.0033040429,0.9753201],"study_design_scores_gemma":[0.00027390252,0.00004700328,0.00080340164,0.03202824,0.00095735566,0.000030469679,0.0000063387547,6.519302e-7,0.0000037379102,0.000038756934,0.96559703,0.000213082],"about_ca_topic_score_codex":0.000028167286,"about_ca_topic_score_gemma":0.000036407706,"teacher_disagreement_score":0.975107,"about_ca_system_score_codex":0.00012465286,"about_ca_system_score_gemma":0.00050285825,"threshold_uncertainty_score":0.99997085},"labels":[],"label_agreement":null},{"id":"W3120936954","doi":"10.1016/j.matbio.2021.01.003","title":"Autophagy, tissue repair, and fibrosis: a delicate balance","year":2021,"lang":"en","type":"review","venue":"Matrix Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Université de Montréal; Translational Research in Oncology","funders":"Canadian Institutes of Health Research; Institute of Nutrition, Metabolism and Diabetes; Université de Montréal; Fondation Jean-Louis Lévesque","keywords":"Autophagy; Myofibroblast; Cell biology; Extracellular matrix; Fibrosis; Intracellular; Biology; Inflammation; Extracellular; Pathology; Immunology; Medicine; Biochemistry","score_opus":0.03417624081086347,"score_gpt":0.4033937773148127,"score_spread":0.36921753650394923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3120936954","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009104928,0.9981827,0.000032073447,0.000085939646,0.00023138536,0.00060471304,0.00011425004,0.0002256846,0.00043220152],"genre_scores_gemma":[0.000026077467,0.99437267,0.0009101317,0.00031417503,0.0004169746,0.00015897022,0.0005721124,0.0000540056,0.003174894],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99826777,0.00019607328,0.00049514073,0.00063471537,0.000070817936,0.00033546097],"domain_scores_gemma":[0.9988311,0.00012446403,0.00019487347,0.0006218508,0.000050629507,0.00017711111],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014602688,0.00038039702,0.0020607344,0.00012067947,0.000056278262,0.000013661887,0.00012827589,0.0005930869,0.00053594116],"category_scores_gemma":[0.000070824266,0.0002810673,0.00043672931,0.00022381455,0.00013661098,0.000018395056,0.00012570446,0.0003193456,0.00022550308],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001993565,0.000081062484,0.000029724662,0.010242079,0.00064946775,0.00032763666,0.000018551726,1.13358425e-8,0.000042831136,0.0015333218,0.0051274276,0.98192793],"study_design_scores_gemma":[0.0003650277,0.00020379332,0.000031989985,0.003786081,0.0010691424,0.0006304859,0.0000033464946,0.0000042698302,0.000028828268,0.000108398526,0.99352854,0.00024008106],"about_ca_topic_score_codex":0.000019175166,"about_ca_topic_score_gemma":6.7451987e-7,"teacher_disagreement_score":0.9884011,"about_ca_system_score_codex":0.000049417566,"about_ca_system_score_gemma":0.0002916147,"threshold_uncertainty_score":0.9999642},"labels":[],"label_agreement":null},{"id":"W3121182123","doi":"10.1101/2021.01.27.428292","title":"AMPK-dependent phosphorylation is required for transcriptional activation of TFEB/TFE3","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Fonds de Recherche du Québec - Santé; Kidney Foundation of Canada; Cancer Research Society; Canadian Institutes of Health Research; Terry Fox Foundation; McGill University","keywords":"TFEB; AMPK; Autophagy; Folliculin; mTORC1; Cell biology; Phosphorylation; TFE3; Mechanistic target of rapamycin; Chemistry; Biology; Cancer research; Protein kinase A; Transcription factor; Biochemistry; Gene; Apoptosis","score_opus":0.023616065873245135,"score_gpt":0.2575957063832983,"score_spread":0.23397964051005318,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3121182123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9762414,0.0026224428,0.017669706,0.00056164194,0.0008063733,0.0014871956,0.00042976902,0.0001708773,0.000010570531],"genre_scores_gemma":[0.9934919,0.00041844964,0.0044872183,0.0006069374,0.00047823766,0.00036535188,0.000010964481,0.00011155313,0.0000293909],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975915,0.00006025543,0.0006641014,0.0007710613,0.0005878255,0.00032527882],"domain_scores_gemma":[0.9973409,0.00006129629,0.00048204334,0.0008896548,0.001020064,0.00020602724],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034999105,0.00040562265,0.0006737561,0.00021544263,0.00009949151,0.00006162038,0.00019632226,0.0005621996,0.000305337],"category_scores_gemma":[0.00012655472,0.00044680148,0.00040476388,0.00027402345,0.00008255483,0.00017988117,0.000064570035,0.00037738314,0.000008101048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005289779,0.0004673976,0.0015528731,0.0011829241,0.0005885516,0.000014096151,0.000054988017,0.000038002396,0.99443096,0.0009154935,0.00021166875,0.000014075675],"study_design_scores_gemma":[0.0019297266,0.00011530267,0.10321826,0.0007856609,0.000397791,1.8411232e-8,0.000010857764,0.0005433643,0.8914623,0.000015611931,0.0011514677,0.00036959985],"about_ca_topic_score_codex":0.000032594686,"about_ca_topic_score_gemma":4.956164e-7,"teacher_disagreement_score":0.10296861,"about_ca_system_score_codex":0.00028312788,"about_ca_system_score_gemma":0.001188511,"threshold_uncertainty_score":0.99979836},"labels":[],"label_agreement":null},{"id":"W3122876563","doi":"10.3389/fmicb.2020.613963","title":"Protein Kinase R Restricts the Intracellular Survival of Mycobacterium tuberculosis by Promoting Selective Autophagy","year":2021,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Canadian Institutes of Health Research; University of Ottawa; Pfizer Canada; Lung Health Foundation; National Sanitarium Association; Natural Sciences and Engineering Research Council of Canada; Pfizer","keywords":"Protein kinase R; Autophagy; Intracellular; Intracellular parasite; Mycobacterium tuberculosis; Biology; Microbiology; Protein kinase A; Cell biology; Kinase; Tuberculosis; Mitogen-activated protein kinase kinase; Medicine; Biochemistry; Apoptosis","score_opus":0.005814664412265568,"score_gpt":0.22427437743591266,"score_spread":0.21845971302364708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3122876563","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888871,0.008026554,0.00057771814,0.0010556914,0.00054175284,0.00063161674,0.000063855296,0.000029463537,0.00018625938],"genre_scores_gemma":[0.99710065,0.00019824888,0.001467484,0.00026903232,0.000090645335,0.00005733201,0.00021872253,0.00002703598,0.00057086133],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99822485,0.0005553666,0.0004023494,0.00037610793,0.00006928026,0.0003720688],"domain_scores_gemma":[0.99923795,0.000054714466,0.00014983345,0.0003517732,0.0001357332,0.00006998545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039916608,0.00018646246,0.0004901125,0.00009083007,0.000060457718,0.000008220391,0.00014717167,0.0002249977,0.000064914275],"category_scores_gemma":[0.00023340392,0.00014313706,0.00012127786,0.00044799593,0.00018678028,0.00003919837,0.00006533631,0.00038176303,0.0000056164736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022199671,0.00032755357,0.009652913,0.000094500974,0.00023389023,0.00015255241,0.00050732074,0.0000013034671,0.9812195,0.000048140122,0.0055152588,0.0020250846],"study_design_scores_gemma":[0.0013367801,0.00021359464,0.004744954,0.000100300786,0.00007625105,0.000066597495,0.00044211993,0.00009171305,0.9876033,0.0002706974,0.004913115,0.00014058303],"about_ca_topic_score_codex":0.000034048586,"about_ca_topic_score_gemma":0.000005543747,"teacher_disagreement_score":0.008213549,"about_ca_system_score_codex":0.00011574667,"about_ca_system_score_gemma":0.0002526887,"threshold_uncertainty_score":0.583696},"labels":[],"label_agreement":null},{"id":"W3123202219","doi":"10.1093/brain/awaa442","title":"Defective phosphatidylethanolamine biosynthesis leads to a broad ataxia-spasticity spectrum","year":2020,"lang":"en","type":"letter","venue":"Brain","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"UCLH Biomedical Research Centre; Medical Research Council; National Institute for Health and Care Research; Brain Research UK; Multiple System Atrophy Trust; Rosetrees Trust; Muscular Dystrophy UK; Wellcome Trust; Muscular Dystrophy Association","keywords":"Spasticity; Ataxia; Phosphatidylethanolamine; Neuroscience; Biosynthesis; Broad spectrum; Medicine; Chemistry; Physical medicine and rehabilitation; Biology; Biochemistry; Phospholipid","score_opus":0.01748763570432918,"score_gpt":0.26311659931365816,"score_spread":0.24562896360932898,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3123202219","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.017702663,0.0011303314,0.0012928956,0.97471464,0.00040702708,0.0013191748,0.00039305034,0.0003817371,0.0026584568],"genre_scores_gemma":[0.044975936,0.000048227124,0.00044165875,0.93944603,0.0064357272,0.00012495417,0.00041316985,0.00018038144,0.007933932],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971873,0.00015120543,0.0003935904,0.0009480076,0.00062024104,0.00069965655],"domain_scores_gemma":[0.99812376,0.0005259243,0.0001710515,0.00075615593,0.00006438818,0.00035873774],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001121354,0.0006220643,0.0010245191,0.00025905384,0.000101373764,0.000044289132,0.00034107757,0.00060383364,0.0017087932],"category_scores_gemma":[0.00080089725,0.0005692176,0.00046461454,0.0005269074,0.000120427154,0.00005227679,0.00012591953,0.0014024411,0.001967818],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033520287,0.000095382624,0.00027898359,0.00029190624,0.0004384717,0.003494304,0.00025433747,5.75727e-7,0.0024604783,0.000033811102,0.989992,0.0023245506],"study_design_scores_gemma":[0.0012193669,0.00076061755,0.0049436335,0.00047515956,0.00043437432,0.000076752774,0.00001508749,0.00002926423,0.039617747,0.00054508256,0.951206,0.000676913],"about_ca_topic_score_codex":0.00010562159,"about_ca_topic_score_gemma":0.000009702712,"teacher_disagreement_score":0.038785994,"about_ca_system_score_codex":0.00022140668,"about_ca_system_score_gemma":0.00027138623,"threshold_uncertainty_score":0.9996759},"labels":[],"label_agreement":null},{"id":"W3123385235","doi":"10.1155/2021/8880179","title":"Cardiac Shock Wave Therapy Alleviates Hypoxia/Reoxygenation‐Induced Myocardial Necroptosis by Modulating Autophagy","year":2021,"lang":"en","type":"article","venue":"BioMed Research International","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Capital Health","keywords":"Necroptosis; Autophagy; Viability assay; Autophagosome; Programmed cell death; Apoptosis; Cell biology; Cardioprotection; Reperfusion injury; Chemistry; Reactive oxygen species; Biology; Molecular biology; Ischemia; Medicine; Biochemistry; Internal medicine","score_opus":0.10143060432362501,"score_gpt":0.38263630405915333,"score_spread":0.28120569973552834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3123385235","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9781684,0.0037609225,0.00013179725,0.007190117,0.0018366622,0.0005277135,0.00020231502,0.00012641879,0.0080556525],"genre_scores_gemma":[0.9877184,0.0019696783,0.0007012026,0.00059425586,0.0017950201,0.00016913463,0.0010465315,0.00006018183,0.005945566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9960391,0.00036358574,0.00042408486,0.00061760796,0.0019473905,0.0006082629],"domain_scores_gemma":[0.99740344,0.0003194843,0.0000842527,0.00046945753,0.0013541754,0.00036916655],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008714624,0.00023643578,0.00036753697,0.00040918903,0.000283352,0.00016741076,0.00027795788,0.00020276512,0.0019957745],"category_scores_gemma":[0.0005465511,0.00021319577,0.00035129776,0.00066941406,0.00015296665,0.0001910448,0.00017937967,0.0004809788,0.00017555391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033306793,0.00060596684,0.0014080312,0.000020664866,0.0016091837,0.00019353357,0.00032949133,0.000004294208,0.912195,0.0008989294,0.036776602,0.04562518],"study_design_scores_gemma":[0.004334649,0.00036318315,0.07604726,0.00010364218,0.000036329035,0.000050381466,0.00041719805,0.0037858812,0.7529298,0.0015157515,0.16001028,0.0004056119],"about_ca_topic_score_codex":0.00008823851,"about_ca_topic_score_gemma":0.0000012662153,"teacher_disagreement_score":0.15926522,"about_ca_system_score_codex":0.00037912567,"about_ca_system_score_gemma":0.0005807372,"threshold_uncertainty_score":0.9989165},"labels":[],"label_agreement":null},{"id":"W3124252970","doi":"10.1139/bcb-2020-0445","title":"Role of SIRT2 in regulating the dexamethasone-activated autophagy pathway in skeletal muscle atrophy","year":2021,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China; Natural Science Foundation of Shanghai","keywords":"SIRT2; Myogenesis; Muscle atrophy; Skeletal muscle; Autophagy; Sirtuin; Chemistry; C2C12; Internal medicine; Endocrinology; Small hairpin RNA; Biology; Western blot; Gastrocnemius muscle; Cell biology; Biochemistry; Gene knockdown; Medicine; Apoptosis; Acetylation","score_opus":0.007582655832382081,"score_gpt":0.23727376432894812,"score_spread":0.22969110849656604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3124252970","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98947465,0.007340775,0.000001857578,0.000079176214,0.000022386117,0.00007190627,0.000008523769,0.000009676484,0.0029910358],"genre_scores_gemma":[0.9992823,0.00014308149,0.00009734009,0.00010794472,0.000052062987,0.000009380637,0.000048362544,0.000007150817,0.00025235894],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992938,0.00006685777,0.0002044908,0.00022584811,0.00004311001,0.00016590492],"domain_scores_gemma":[0.9995736,0.000083331746,0.00006643176,0.00020562917,0.000026505078,0.000044486613],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000102801394,0.00009949404,0.00021168403,0.000021321053,0.000023365246,0.0000029218338,0.000053473537,0.00016468012,0.00012108753],"category_scores_gemma":[0.000053416043,0.000075051124,0.000053513817,0.00015651436,0.00012553022,0.000010072089,0.000042636268,0.00015644236,0.0000011067768],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049113372,0.00014272814,0.0028556148,0.000055835444,0.000014050177,0.000029121993,0.0001234871,0.0000021539097,0.9812057,0.000064007225,0.000002902373,0.015455308],"study_design_scores_gemma":[0.000979644,0.0000629814,0.023510056,0.000034729535,0.000007674004,0.0000129796845,0.00045704344,0.00007596709,0.9732685,0.0003731757,0.0011458079,0.000071427414],"about_ca_topic_score_codex":0.000037787377,"about_ca_topic_score_gemma":0.0000034839384,"teacher_disagreement_score":0.020654442,"about_ca_system_score_codex":0.000017898747,"about_ca_system_score_gemma":0.0001029841,"threshold_uncertainty_score":0.30604962},"labels":[],"label_agreement":null},{"id":"W3125441627","doi":"10.2139/ssrn.3155894","title":"Enteroviral Infection Inhibits Autophagic Flux via Disruption of the SNARE Complex to Enhance Viral Replication","year":2018,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Replication (statistics); Virology; Viral replication; Autophagy; Cell biology; Viral infection; Biology; Virus; Genetics; Apoptosis","score_opus":0.010400689079438983,"score_gpt":0.3136998906156549,"score_spread":0.3032992015362159,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3125441627","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9824235,0.00025869487,0.015090953,0.0012363641,0.00022265634,0.00034398164,0.0000024768597,0.00003557826,0.00038580236],"genre_scores_gemma":[0.9971856,0.00015474964,0.00004355213,0.0007796963,0.0005710117,0.000011984597,0.000014260234,0.000020015801,0.0012191654],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832857,0.000089275774,0.00033112222,0.00022690865,0.00029411732,0.0007300332],"domain_scores_gemma":[0.9990637,0.000013081334,0.00022968602,0.00041825927,0.00018648883,0.00008883493],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054376054,0.0001338083,0.00017996746,0.00009616521,0.00021361277,0.000015344287,0.00013737363,0.000068038986,0.00013429413],"category_scores_gemma":[0.00006846769,0.00009577659,0.00015716138,0.00024495093,0.00008915237,0.00013741535,0.00003729924,0.00060062006,0.000069421054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013206438,0.00059905846,0.03556956,0.000047810332,0.0003827549,0.0000025273362,0.00093195244,0.000016254107,0.8078537,0.009060981,0.000878029,0.14333673],"study_design_scores_gemma":[0.0018874721,0.004567986,0.45550674,0.00021618571,0.00021342623,0.0007468011,0.00015913638,0.0005701649,0.48438355,0.04744979,0.0040194513,0.0002793003],"about_ca_topic_score_codex":0.000049447997,"about_ca_topic_score_gemma":0.00013616968,"teacher_disagreement_score":0.4199372,"about_ca_system_score_codex":0.00057892717,"about_ca_system_score_gemma":0.0004944783,"threshold_uncertainty_score":0.39056557},"labels":[],"label_agreement":null},{"id":"W3126298132","doi":"10.1186/s12885-021-08928-9","title":"Nomogram based on autophagy related genes for predicting the survival in melanoma","year":2021,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SKiN Health","funders":"Xiangya Hospital, Central South University; China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"Nomogram; Receiver operating characteristic; Oncology; Univariate; Medicine; Lasso (programming language); Melanoma; Cohort; Concordance; Survival analysis; Internal medicine; Multivariate analysis; Area under the curve; Multivariate statistics; Cancer research; Computer science; Machine learning","score_opus":0.029365666520066235,"score_gpt":0.31982956054068323,"score_spread":0.290463894020617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3126298132","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888211,0.005806277,0.00035631875,0.0012060209,0.0007288005,0.0005650236,0.000048749847,0.000077623976,0.0023900925],"genre_scores_gemma":[0.99600077,0.000104171166,0.00026367008,0.0011248669,0.0003272799,0.00030674375,0.000047156005,0.000028813738,0.0017965077],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99913085,0.0000651756,0.00019379443,0.00022997912,0.00017016733,0.00021003498],"domain_scores_gemma":[0.9992918,0.00024994742,0.000052540243,0.00028077874,0.000064690445,0.00006025712],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018856427,0.00010876773,0.00019020929,0.00004161721,0.00007016618,0.000013014469,0.000066197965,0.000077660465,0.0004898557],"category_scores_gemma":[0.00008973842,0.00007691939,0.00012683355,0.00021772839,0.00003250417,0.000021817066,0.000012324102,0.00012111736,0.0000068773466],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034920308,0.0012489756,0.87109673,0.00059225195,0.0005590875,0.00037613403,0.0012245951,0.009622003,0.009360205,0.0025007282,0.0024223211,0.09750492],"study_design_scores_gemma":[0.010741184,0.00040577984,0.7994006,0.0004915907,0.00028114195,0.000014450969,0.0003717713,0.11592262,0.04356162,0.0005061945,0.027996732,0.00030631488],"about_ca_topic_score_codex":0.000108054366,"about_ca_topic_score_gemma":0.00031663207,"teacher_disagreement_score":0.106300615,"about_ca_system_score_codex":0.00008700649,"about_ca_system_score_gemma":0.0005033641,"threshold_uncertainty_score":0.5363577},"labels":[],"label_agreement":null},{"id":"W3127725287","doi":"10.1016/j.tibs.2021.01.004","title":"Beyond Autophagy: The Expanding Roles of ATG8 Proteins","year":2021,"lang":"en","type":"review","venue":"Trends in Biochemical Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":130,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institute on Aging; National Cancer Institute; National Institutes of Health; Government of Canada; Cancer Research Society; Fundación Ramón Areces","keywords":"ATG8; Autophagy; Cell biology; Biogenesis; Autophagosome; Biology; Vesicle; Non canonical; Biochemistry; Membrane; Gene","score_opus":0.0688104214369031,"score_gpt":0.41366360691985704,"score_spread":0.34485318548295396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3127725287","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0031359296,0.99126565,0.000001653394,0.00015278385,0.00009754412,0.0002492103,0.000019448911,0.000023064567,0.0050547337],"genre_scores_gemma":[0.004260722,0.99448436,0.00026197365,0.00007233673,0.00019078847,0.00009479665,0.000055528955,0.000015169482,0.0005643098],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980695,0.000102253514,0.000533913,0.00047467975,0.0004980194,0.0003216],"domain_scores_gemma":[0.9991022,0.00016982602,0.00023248806,0.00036922333,0.000026202613,0.00010007915],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046770994,0.00026837474,0.0011572593,0.0002551487,0.00008534587,0.000027814765,0.00050223747,0.00022448334,0.00052780734],"category_scores_gemma":[0.00009788276,0.00013991313,0.0004752831,0.0017939145,0.0008148844,0.000040144958,0.00013010476,0.00032377223,0.000006507461],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000055831447,0.00016574659,0.00002279547,0.0010961932,0.000070183356,0.000030362044,0.00011188152,1.1851916e-7,0.0003150993,0.0008880659,0.0005795725,0.9967144],"study_design_scores_gemma":[0.0010866397,0.00047318437,0.0002133528,0.0380302,0.0013223503,0.00019524981,0.00038118902,0.000031835967,0.031989485,0.0012887785,0.9240747,0.00091304386],"about_ca_topic_score_codex":0.000012512988,"about_ca_topic_score_gemma":0.0000026006448,"teacher_disagreement_score":0.9958013,"about_ca_system_score_codex":0.000064157015,"about_ca_system_score_gemma":0.00033858488,"threshold_uncertainty_score":0.57791203},"labels":[],"label_agreement":null},{"id":"W3128283808","doi":"10.26443/mjm.v15i1.180","title":"2016 Nobel Prize Winner Yoshinori Ohsumi; Solving the Mystery of Autophagy","year":2017,"lang":"en","type":"article","venue":"McGill Journal of Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Physiology; Psychoanalysis; Gerontology; Psychology","score_opus":0.040846015797020394,"score_gpt":0.3264390398791315,"score_spread":0.28559302408211107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3128283808","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9192095,0.011542721,0.00034484544,0.046525814,0.0033244342,0.00047136514,0.000020501411,0.00003197885,0.018528884],"genre_scores_gemma":[0.9905949,0.0012519886,0.00019221536,0.003789038,0.0018247655,0.0000022629172,0.0000016920538,0.000030056983,0.0023130572],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9978608,0.00008081547,0.0008685772,0.00015071793,0.0007627854,0.0002763262],"domain_scores_gemma":[0.99690205,0.00019948192,0.0013764247,0.0008286471,0.00043220838,0.00026117737],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012527461,0.00020653036,0.0007596694,0.00014916886,0.00038563512,0.000012908419,0.00060365145,0.00010295111,0.000501098],"category_scores_gemma":[0.000792548,0.000103140424,0.00024637202,0.000071695715,0.0004966419,0.00022198918,0.000079286445,0.00044133593,0.00001919433],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0063605458,0.0017099085,0.017523283,0.0011776988,0.004758628,0.00513486,0.0038192116,0.000033742243,0.5207741,0.0054160655,0.22497757,0.20831436],"study_design_scores_gemma":[0.042032603,0.0066344365,0.48346525,0.010603779,0.0032306116,0.004954779,0.0014511197,0.0003361436,0.10677672,0.0047658994,0.33508638,0.00066226843],"about_ca_topic_score_codex":0.000054958928,"about_ca_topic_score_gemma":0.000002426577,"teacher_disagreement_score":0.46594197,"about_ca_system_score_codex":0.0000593083,"about_ca_system_score_gemma":0.00014494357,"threshold_uncertainty_score":0.5486672},"labels":[],"label_agreement":null},{"id":"W3128541985","doi":"10.1016/j.molmet.2021.101185","title":"Distinct roles of UVRAG and EGFR signaling in skeletal muscle homeostasis","year":2021,"lang":"en","type":"article","venue":"Molecular Metabolism","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Toronto Rehabilitation Institute; University of Toronto; Toronto General Hospital; University Health Network","funders":"Institute of Nutrition, Metabolism and Diabetes; Canadian Institutes of Health Research","keywords":"Skeletal muscle; Homeostasis; Cell biology; Signal transduction; Biology; Neuroscience; Endocrinology","score_opus":0.007792032584292605,"score_gpt":0.25389015474973764,"score_spread":0.24609812216544502,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3128541985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9422726,0.056710575,0.00027219485,0.00021252823,0.000053253603,0.0000998894,0.000020389629,0.000016734642,0.00034185505],"genre_scores_gemma":[0.9983825,0.00041116044,0.00067071733,0.00038194816,0.000046630063,0.0000092141445,0.000032765565,0.000021494312,0.000043563643],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991001,0.00007385293,0.00022136226,0.00022606544,0.00020354982,0.0001750969],"domain_scores_gemma":[0.9995176,0.000025441444,0.000051654173,0.00023885952,0.00006467664,0.00010175417],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010225411,0.0001222147,0.00035394143,0.00008652828,0.000021949307,0.000010229305,0.000047466092,0.000050697523,0.00014188544],"category_scores_gemma":[0.000077883065,0.00011445356,0.00011656904,0.00023675816,0.00006211162,0.00003695207,0.000033968376,0.000110090834,0.000003735384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039675917,0.0003135329,0.0021304626,0.00012086131,0.00017765975,0.0015045634,0.00052261684,0.000011728808,0.9189569,0.0029427765,0.000022275706,0.073256955],"study_design_scores_gemma":[0.0023465927,0.00003139609,0.34649202,0.00010185513,0.0002501404,0.000021672837,0.0002649109,0.00007500822,0.64020133,0.0015461979,0.008493891,0.00017495351],"about_ca_topic_score_codex":0.000027724533,"about_ca_topic_score_gemma":0.000009410646,"teacher_disagreement_score":0.34436157,"about_ca_system_score_codex":0.000008912568,"about_ca_system_score_gemma":0.000070171416,"threshold_uncertainty_score":0.4667281},"labels":[],"label_agreement":null},{"id":"W3128906107","doi":"10.1139/bcb-2020-0570","title":"Cetrimonium bromide promotes the clearance of lipids by activating the TFEB-mediated autophagosome–lysosome pathway in hepatic cells","year":2021,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Tianjin Municipal Education Commission; University of Manchester","keywords":"TFEB; Autophagy; Lysosome; Cell biology; mTORC1; Autophagosome; Mechanistic target of rapamycin; Chemistry; PI3K/AKT/mTOR pathway; Biogenesis; Biology; Biochemistry; Signal transduction; Gene","score_opus":0.006694418427370933,"score_gpt":0.2281784971677503,"score_spread":0.22148407874037937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3128906107","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98445326,0.013864868,0.0000041678595,0.0005083337,0.00006887252,0.00018073533,0.00003798597,0.000017242488,0.00086452346],"genre_scores_gemma":[0.99763453,0.0009819807,0.00003188163,0.00046284785,0.00010241325,0.000020890253,0.00008233738,0.000011642552,0.0006714785],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905896,0.00009034341,0.00026716085,0.00027329766,0.0000784508,0.00023178778],"domain_scores_gemma":[0.99917805,0.00025432394,0.00012341805,0.00032543216,0.000049585306,0.00006920308],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015374347,0.00014772659,0.00028318173,0.000016190043,0.00006850482,0.000008193337,0.000107398184,0.00019233287,0.00007606362],"category_scores_gemma":[0.000103908525,0.00008878779,0.000068704714,0.0002192861,0.00025450604,0.000016064165,0.000055129,0.00024971247,0.0000042829847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013748782,0.00025005802,0.0033911248,0.00021023603,0.00004448187,0.000016865137,0.00013060997,3.5353094e-7,0.99402344,0.000009266443,0.0000883928,0.001697704],"study_design_scores_gemma":[0.0010888124,0.00012782526,0.004361434,0.000071778326,0.000021764386,0.000014841474,0.00022756691,0.000088890316,0.9924032,0.00005872389,0.0014445852,0.000090546164],"about_ca_topic_score_codex":0.000018505916,"about_ca_topic_score_gemma":4.8205567e-7,"teacher_disagreement_score":0.013181258,"about_ca_system_score_codex":0.000019753184,"about_ca_system_score_gemma":0.00018669323,"threshold_uncertainty_score":0.36206612},"labels":[],"label_agreement":null},{"id":"W3129411218","doi":"10.4103/1673-5374.308091","title":"Regulating autophagy: a novel role for SETX (Senataxin)","year":2021,"lang":"en","type":"article","venue":"Neural Regeneration Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Autophagy; Computer science; Neuroscience; Computational biology; Medicine; Cognitive science; Biology; Psychology; Genetics","score_opus":0.12423847448736611,"score_gpt":0.4281555111067608,"score_spread":0.30391703661939473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3129411218","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98758876,0.0014487065,0.0017091038,0.006670725,0.00016420399,0.0006774313,0.00003433314,0.00008520634,0.0016215527],"genre_scores_gemma":[0.9784312,0.000037837377,0.0036853324,0.00078176433,0.000847933,0.00017550011,0.00030721247,0.000036344183,0.015696848],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982009,0.000110486864,0.00023715243,0.00039242159,0.0006508047,0.00040826734],"domain_scores_gemma":[0.9983215,0.00019226852,0.0000382316,0.0004111125,0.0008426912,0.00019425072],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004937885,0.00011315994,0.0001874519,0.00012346052,0.00035844865,0.00009157047,0.00008715775,0.0001059172,0.00025411526],"category_scores_gemma":[0.000596601,0.00010123622,0.00012259789,0.000418525,0.000064982734,0.00012224699,0.000055189925,0.0002688215,0.000029595802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021367511,0.00017307524,0.00014375849,0.0000633136,0.000042897467,0.00004824165,0.000107528154,0.000180832,0.96548754,0.010344155,0.0038220556,0.0193729],"study_design_scores_gemma":[0.0018455562,0.00021152594,0.002259612,0.000036076082,0.000016651744,0.00006971759,0.0001165816,0.086790085,0.8907196,0.0008679773,0.016967831,0.000098799785],"about_ca_topic_score_codex":0.000018138715,"about_ca_topic_score_gemma":0.000016260181,"teacher_disagreement_score":0.08660925,"about_ca_system_score_codex":0.000083461375,"about_ca_system_score_gemma":0.00042816577,"threshold_uncertainty_score":0.4128293},"labels":[],"label_agreement":null},{"id":"W3130068577","doi":"10.1101/2021.02.18.431643","title":"A genetic program boosts mitochondrial function to power macrophage tissue invasion","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Institute of Science and Technology Austria; National Institutes of Health; Austrian Science Fund; European Commission; Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Oxidative phosphorylation; Cell biology; Mitochondrion; Drosophila melanogaster; Phosphorylation; Bioenergetics; Gene; Genetics; Biochemistry","score_opus":0.011261814455148823,"score_gpt":0.25102969741448244,"score_spread":0.23976788295933363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3130068577","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98657584,0.00347178,0.0018899763,0.00032861263,0.0036268819,0.0032416065,0.00007732733,0.00076778576,0.000020207734],"genre_scores_gemma":[0.9801946,0.00019264907,0.015607267,0.0014585593,0.001562012,0.0006977491,0.0000023725631,0.00023207719,0.000052693744],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964239,0.00015466684,0.000624944,0.0014242196,0.00068872806,0.0006835649],"domain_scores_gemma":[0.9963622,0.000030455292,0.00026065938,0.001831931,0.0006696943,0.00084504124],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001771488,0.00069818366,0.0008197206,0.0003256285,0.00014838863,0.0002728387,0.00032734973,0.0007895677,0.00073974836],"category_scores_gemma":[0.00019803147,0.0007251779,0.00029217105,0.00063467905,0.000077389675,0.00009925175,0.0004505913,0.00084031525,0.00037157562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052460114,0.00090096385,0.0016890389,0.0005328261,0.0004332928,0.0013115086,0.000030870637,0.000023366812,0.9929566,0.000027915074,0.001478707,0.00009030318],"study_design_scores_gemma":[0.002477775,0.0011669956,0.35828188,0.0013252955,0.0007758983,2.454906e-7,0.000009411817,0.00007448937,0.6056045,0.0000021838766,0.0291018,0.0011795158],"about_ca_topic_score_codex":0.000035529443,"about_ca_topic_score_gemma":0.0000030511724,"teacher_disagreement_score":0.38735208,"about_ca_system_score_codex":0.00031982065,"about_ca_system_score_gemma":0.0010265616,"threshold_uncertainty_score":0.99951994},"labels":[],"label_agreement":null},{"id":"W3130764299","doi":"10.1139/cjpp-2020-0449","title":"Effect of casein kinase 1α inhibition on autophagy flux and the AKT/phospho-β-catenin (S552) axis in HCT116, a RAS-mutated colorectal cancer cell line","year":2021,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"","keywords":"Casein kinase 1; Protein kinase B; Wnt signaling pathway; Autophagy; Catenin; PI3K/AKT/mTOR pathway; Cancer research; Oncogene; Phosphorylation; Biology; Cell growth; Signal transduction; Cell biology; Apoptosis; Chemistry; Protein kinase A; Cell cycle; Biochemistry","score_opus":0.006439247404209809,"score_gpt":0.2810604257010295,"score_spread":0.2746211782968197,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3130764299","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9827803,0.014949862,9.1091016e-7,0.0013349699,0.0005330378,0.00026191532,0.00004881603,0.0000032953749,0.00008694407],"genre_scores_gemma":[0.99624,0.0014727295,0.0000059122617,0.0018544741,0.0002870635,0.000022260954,0.000024975052,0.000013511495,0.00007905081],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985025,0.0006222328,0.00035565413,0.00018305378,0.00006376725,0.00027278933],"domain_scores_gemma":[0.9988503,0.0004096752,0.00020572823,0.00006756862,0.00013213574,0.00033463366],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00038597974,0.00016925609,0.00059637567,0.00013791514,0.00008918304,0.0000043412815,0.000055819975,0.00016155884,0.0018570228],"category_scores_gemma":[0.00004138551,0.00011748633,0.00010228165,0.00017965838,0.00047524646,0.000047932182,0.00001371899,0.00042928694,0.000002316597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007612735,0.00010623259,0.00075150724,0.0001954267,0.00025141076,0.0027077252,0.00075684,0.00009584721,0.9833271,0.00007422672,0.0011224948,0.0029984508],"study_design_scores_gemma":[0.013654753,0.002018694,0.00969536,0.00007300886,0.00029641046,0.00037032616,0.00008001624,0.0002567832,0.97284395,0.00025232084,0.00036582825,0.00009254724],"about_ca_topic_score_codex":0.002100284,"about_ca_topic_score_gemma":0.001983255,"teacher_disagreement_score":0.013477133,"about_ca_system_score_codex":0.00010034294,"about_ca_system_score_gemma":0.00088114064,"threshold_uncertainty_score":0.9990554},"labels":[],"label_agreement":null},{"id":"W3130949183","doi":"10.1016/j.tibs.2021.01.006","title":"Regulation of Autophagy Enzymes by Nutrient Signaling","year":2021,"lang":"en","type":"review","venue":"Trends in Biochemical Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Enzyme; Cell biology; Signal transduction; Biology; Nutrient; Nutrient sensing; Biochemistry; Chemistry; Ecology; Apoptosis","score_opus":0.062240494511477576,"score_gpt":0.39838143729909414,"score_spread":0.3361409427876166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3130949183","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001967166,0.99660015,0.000007723928,0.000044104658,0.00008476069,0.00011793047,0.000025802929,0.000021772476,0.0011305895],"genre_scores_gemma":[0.0071244915,0.99148047,0.00034484724,0.000035423735,0.000101287485,0.000025711366,0.0002789322,0.000012486116,0.00059636566],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981794,0.00007441547,0.0005810349,0.00046973827,0.00044995127,0.00024545635],"domain_scores_gemma":[0.99926215,0.00013093471,0.00024399496,0.00022408394,0.000032434895,0.00010641809],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029409782,0.0002254413,0.0011100793,0.00028230692,0.000037097754,0.00001537097,0.00022757301,0.0002474049,0.00082605047],"category_scores_gemma":[0.000060282113,0.00015989777,0.00035432985,0.0015734677,0.00037705913,0.00003849824,0.00005260235,0.00018203266,0.0000042663505],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000101925,0.0003803929,0.000015143595,0.002001188,0.00007447266,0.0000149613425,0.000047717138,4.920859e-7,0.0041168826,0.0014256218,0.0052535,0.9866594],"study_design_scores_gemma":[0.0006539143,0.00023070046,0.00004470589,0.019495036,0.0005423988,0.000037718022,0.000040635063,0.000042041745,0.15923776,0.0003786674,0.81883764,0.00045877945],"about_ca_topic_score_codex":0.000010695968,"about_ca_topic_score_gemma":1.699163e-7,"teacher_disagreement_score":0.98620063,"about_ca_system_score_codex":0.000079188,"about_ca_system_score_gemma":0.0002196512,"threshold_uncertainty_score":0.9044673},"labels":[],"label_agreement":null},{"id":"W3132918862","doi":"10.1101/2021.02.22.432209","title":"GABARAP membrane conjugation sequesters the FLCN-FNIP tumor suppressor complex to activate TFEB and lysosomal biogenesis","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; Cancer Research UK","keywords":"TFEB; ATG8; Cell biology; Autophagy; Chemistry; Biogenesis; Mitophagy; Lysosome; ULK1; Sequestosome 1; Biology; Phosphorylation; Biochemistry; Protein kinase A","score_opus":0.022511790851601366,"score_gpt":0.25117440967708654,"score_spread":0.22866261882548516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3132918862","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932572,0.0015421059,0.00023378717,0.0020917978,0.0006186903,0.0015710215,0.00035842834,0.0003119049,0.000015017612],"genre_scores_gemma":[0.99369675,0.0003040715,0.0014963031,0.0034270266,0.000572954,0.0003281266,0.0000054695233,0.00015905245,0.000010243577],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99693257,0.00025661936,0.00056514627,0.0011133063,0.00054817734,0.0005841901],"domain_scores_gemma":[0.9969637,0.00012537996,0.0003248729,0.0015258908,0.0004920191,0.000568148],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039856977,0.0006623474,0.00086609455,0.00025389186,0.00026704252,0.00030383366,0.00039307243,0.00032682368,0.00022166036],"category_scores_gemma":[0.00016963194,0.0005604188,0.00024094331,0.0004941942,0.00022519247,0.00015354274,0.00044606818,0.00054375484,0.000039050836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029766755,0.00016693982,0.0040446064,0.00058899296,0.000600963,0.0002976637,0.0000562095,0.000026433923,0.9935589,0.00012907365,0.00022684084,0.0000057283105],"study_design_scores_gemma":[0.0010322542,0.00008833285,0.28316462,0.00043926755,0.00043670723,3.781513e-7,0.000021796517,0.0002360869,0.7124345,0.0000010585604,0.0016340985,0.00051094446],"about_ca_topic_score_codex":0.00009250893,"about_ca_topic_score_gemma":0.0000029862897,"teacher_disagreement_score":0.2811244,"about_ca_system_score_codex":0.0002007776,"about_ca_system_score_gemma":0.00063111715,"threshold_uncertainty_score":0.99968475},"labels":[],"label_agreement":null},{"id":"W3133295747","doi":"10.1139/bcb-2020-0636","title":"DUSP4 inhibits autophagic cell death in PTC by inhibiting JNK–BCL2–Beclin1 signaling","year":2021,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autophagy; Gene knockdown; Cell biology; Carcinogenesis; Programmed cell death; Phosphorylation; Cancer research; Chemistry; Gene silencing; Downregulation and upregulation; Biology; Biochemistry; Apoptosis","score_opus":0.011044780349335037,"score_gpt":0.25404381042423196,"score_spread":0.24299903007489693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133295747","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9719513,0.018356288,0.000022498987,0.0002192716,0.00006391683,0.00009706391,0.000033671153,0.000046112524,0.009209851],"genre_scores_gemma":[0.9946571,0.0006763051,0.00020655686,0.0011789768,0.00019345466,0.000013546606,0.00035869473,0.000019170904,0.0026961837],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998644,0.00006104395,0.00033365248,0.00051724137,0.0000777288,0.00036631007],"domain_scores_gemma":[0.99937576,0.00009181849,0.000096120864,0.000197541,0.000053692787,0.00018503655],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015477098,0.00022167966,0.00034127015,0.000034082583,0.00007430929,0.000015218798,0.00006512236,0.0003553609,0.00033649328],"category_scores_gemma":[0.000045480934,0.00021004699,0.000087890316,0.00015241685,0.00009016968,0.000025440335,0.00007179027,0.0002942819,0.000017647257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000069407324,0.00026995654,0.007328207,0.0002108189,0.000018008084,0.0002007665,0.0000793825,8.937751e-7,0.99061465,0.00002333753,0.00024707892,0.0009374839],"study_design_scores_gemma":[0.001906056,0.00008708523,0.00034089244,0.00007997455,0.000037936177,0.000041041094,0.0001939694,0.000048464804,0.9942582,0.00019676053,0.0025976342,0.00021193584],"about_ca_topic_score_codex":0.000016478132,"about_ca_topic_score_gemma":7.770505e-7,"teacher_disagreement_score":0.022705784,"about_ca_system_score_codex":0.000037339738,"about_ca_system_score_gemma":0.0001731791,"threshold_uncertainty_score":0.85654676},"labels":[],"label_agreement":null},{"id":"W3133656915","doi":"10.1016/j.cub.2021.02.034","title":"Friendly mediates membrane depolarization-induced mitophagy in Arabidopsis","year":2021,"lang":"en","type":"article","venue":"Current Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Chinese University of Hong Kong; Rural Development Administration; Research Grants Council, University Grants Committee; Austrian Science Fund; Österreichischen Akademie der Wissenschaften","keywords":"Biology; Depolarization; Arabidopsis; Mitophagy; Cell biology; Biophysics; Biochemistry; Gene; Autophagy; Mutant","score_opus":0.026058153708950125,"score_gpt":0.3264486595290847,"score_spread":0.30039050582013455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133656915","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98465055,0.012733537,0.000186942,0.00052278856,0.0011587853,0.00014729257,0.000015996948,0.000049472088,0.0005346241],"genre_scores_gemma":[0.9973952,0.0013189174,0.00011263957,0.00034146008,0.0003115782,0.000028327067,0.00042013024,0.0000137350935,0.000057971116],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989972,0.00009790002,0.0002595182,0.0003088048,0.00007947154,0.00025708156],"domain_scores_gemma":[0.9994126,0.000086429354,0.000054903416,0.00024962076,0.00007793463,0.00011851052],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000704272,0.000132245,0.00029692703,0.00010901478,0.00003399133,0.0000065874447,0.0000742301,0.00013523106,0.0005916512],"category_scores_gemma":[0.00016464919,0.00011473673,0.00008524639,0.00031871526,0.000066106775,0.00003748053,0.0000350044,0.00019465813,0.00009147192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001618226,0.0011188334,0.27389726,0.00015546408,0.00015871297,0.00026184254,0.0003787699,0.0000022313702,0.622726,0.005876826,0.0003444459,0.09491781],"study_design_scores_gemma":[0.0044895643,0.00028364934,0.21190333,0.00014386563,0.00009417482,0.00007663753,0.00013315932,0.00017189846,0.7600695,0.0025545256,0.01972949,0.0003502233],"about_ca_topic_score_codex":0.000012988747,"about_ca_topic_score_gemma":0.00001618173,"teacher_disagreement_score":0.13734348,"about_ca_system_score_codex":0.000033672382,"about_ca_system_score_gemma":0.00020683433,"threshold_uncertainty_score":0.64781654},"labels":[],"label_agreement":null},{"id":"W3133917005","doi":"10.3390/cancers13051038","title":"Erb-b2 Receptor Tyrosine Kinase 2 (ERBB2) Promotes ATG12-Dependent Autophagy Contributing to Treatment Resistance of Breast Cancer Cells","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"CancerCare Manitoba Foundation","keywords":"ATG12; Autophagy; Downregulation and upregulation; Cancer research; Lapatinib; Programmed cell death; Cancer; Breast cancer; Cancer cell; Epidermal growth factor receptor; Tyrosine kinase; Receptor tyrosine kinase; Biology; Medicine; Receptor; Apoptosis; Internal medicine; ATG5; Trastuzumab; Gene","score_opus":0.012813767236545563,"score_gpt":0.2836228541169782,"score_spread":0.27080908688043265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133917005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97900546,0.014800695,0.00012769966,0.0021588143,0.0008229778,0.00079635065,0.0013442602,0.00009360101,0.0008501279],"genre_scores_gemma":[0.9875204,0.001475463,0.00045546665,0.0008986343,0.00046162395,0.00019464195,0.000072235096,0.00004848837,0.0088730445],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981937,0.00005818486,0.00038368907,0.0004907654,0.00033602162,0.000537671],"domain_scores_gemma":[0.99856323,0.000055331348,0.00016529123,0.000492564,0.00036296007,0.0003606158],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011989025,0.00026531555,0.00056398497,0.000065206295,0.0001133569,0.000018737514,0.00010575594,0.00009718381,0.0019004092],"category_scores_gemma":[0.00004041581,0.00023301496,0.00017684935,0.00035726305,0.000078091405,0.000058378806,0.000044416505,0.00010735407,0.000037456237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020282888,0.0003435971,0.0020621817,0.00033441,0.0006706144,0.0004360201,0.0010453947,0.000396597,0.97313213,0.000259248,0.00449692,0.014794572],"study_design_scores_gemma":[0.0033955113,0.0002393988,0.0068997336,0.00064098515,0.00021246773,0.000012508894,0.00022311135,0.000052379157,0.9699904,0.000031126245,0.018074978,0.00022741534],"about_ca_topic_score_codex":0.00061968475,"about_ca_topic_score_gemma":0.00029640333,"teacher_disagreement_score":0.014567156,"about_ca_system_score_codex":0.0026339625,"about_ca_system_score_gemma":0.0019172851,"threshold_uncertainty_score":0.999012},"labels":[],"label_agreement":null},{"id":"W3135211510","doi":"10.1172/jci94229","title":"Macrophage SR-BI modulates autophagy via VPS34 complex and PPARα transcription of Tfeb in atherosclerosis","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Thrombosis and Atherosclerosis Research Institute","funders":"Vanderbilt University; National Eye Institute; National Institutes of Health; National Cancer Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Autophagy; TFEB; Cell biology; Basic helix-loop-helix leucine zipper transcription factors; Lysosome; Foam cell; Transcription factor; Biology; Inflammation; Macrophage; Downregulation and upregulation; Apoptosis; Chemistry; Immunology; Biochemistry; Gene; DNA-binding protein","score_opus":0.10494296268656822,"score_gpt":0.37810959072109723,"score_spread":0.273166628034529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135211510","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99634206,0.0013290088,0.00053089554,0.0013626253,0.00023714802,0.000111721274,0.0000055194896,0.000008806724,0.00007219881],"genre_scores_gemma":[0.99424744,0.0013477855,0.003002026,0.0010609251,0.00024184,0.0000015820276,0.000014500721,0.000015277616,0.00006863522],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9976034,0.0002669078,0.0015243256,0.0001641667,0.00031374034,0.00012746984],"domain_scores_gemma":[0.99846005,0.00023143961,0.00062688347,0.00015482854,0.000272435,0.00025437024],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009232342,0.000117890064,0.0006421413,0.00010356627,0.000027840231,0.000014050791,0.0000633247,0.00017586877,0.0002001114],"category_scores_gemma":[0.0004232001,0.00010072505,0.00023734388,0.00022596109,0.00023926863,0.00018830232,0.000013183658,0.00035724667,0.0000030707781],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051651115,0.000683604,0.16252518,0.00018449826,0.0001982352,0.00011061002,0.00058081915,0.000101181045,0.8118055,0.0003496106,0.0001978747,0.022746388],"study_design_scores_gemma":[0.0037777785,0.00053650374,0.87714106,0.00034642656,0.00014228075,0.00006470837,0.00005837492,0.0033385954,0.10800855,0.00633983,0.000167285,0.00007860535],"about_ca_topic_score_codex":0.000011661533,"about_ca_topic_score_gemma":0.000005391796,"teacher_disagreement_score":0.7146159,"about_ca_system_score_codex":0.000027868457,"about_ca_system_score_gemma":0.00020984715,"threshold_uncertainty_score":0.41074485},"labels":[],"label_agreement":null},{"id":"W3135313115","doi":"10.1111/jcmm.16411","title":"<i>Helicobacter</i><i>pylori</i> inhibits autophagic flux and promotes its intracellular survival and colonization by down‐regulating SIRT1","year":2021,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Natural Science Foundation of Shandong Province; National Natural Science Foundation of China","keywords":"Autophagy; Helicobacter pylori; Intracellular; Biology; Flux (metallurgy); Gastritis; Microbiology; Cancer research; Cell biology; Apoptosis; Chemistry; Biochemistry; Genetics","score_opus":0.008438802640562503,"score_gpt":0.24130803696228031,"score_spread":0.2328692343217178,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135313115","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89381194,0.09776327,0.003518143,0.0042210384,0.00020915532,0.00021245034,0.000004992789,0.000016447953,0.00024258779],"genre_scores_gemma":[0.99393034,0.0037435857,0.0004077502,0.0010912871,0.00033453584,0.0000022939462,0.00006545507,0.000038139886,0.00038663525],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998181,0.00014886662,0.0006093182,0.0002898268,0.0005176122,0.00025338714],"domain_scores_gemma":[0.99857956,0.000083062485,0.0003247889,0.00016889295,0.00039386537,0.0004498168],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054043264,0.00025930346,0.000659899,0.00012581781,0.000108558386,0.00003902036,0.000054719065,0.00015271628,0.00009884652],"category_scores_gemma":[0.00026072506,0.00020505699,0.00007397842,0.00021648605,0.00018021764,0.00014291244,0.000056631325,0.0003314791,0.0000010401848],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014174476,0.00012076644,0.00060427084,0.00025345586,0.00023051385,0.0013233721,0.00043653528,0.0000016902404,0.9921743,0.00031278923,0.00033736648,0.0040631406],"study_design_scores_gemma":[0.006086787,0.0010209467,0.0016322737,0.0006977879,0.0006760587,0.0021296367,0.0003536564,0.0005323418,0.97933674,0.0003911424,0.006919334,0.00022327423],"about_ca_topic_score_codex":0.0000054029333,"about_ca_topic_score_gemma":8.303994e-7,"teacher_disagreement_score":0.100118406,"about_ca_system_score_codex":0.000024748268,"about_ca_system_score_gemma":0.00013315781,"threshold_uncertainty_score":0.83619815},"labels":[],"label_agreement":null},{"id":"W3135372426","doi":"10.1080/15548627.2021.1896906","title":"Trehalose causes low-grade lysosomal stress to activate TFEB and the autophagy-lysosome biogenesis response","year":2021,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":135,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ted Rogers Centre for Heart Research; Toronto General Hospital; University of Toronto","funders":"National Center for Complementary and Integrative Health; American Diabetes Association; National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Foundation for Barnes-Jewish Hospital; U.S. Department of Veterans Affairs","keywords":"TFEB; Autophagy; Lysosome; Trehalose; Cell biology; Biology; ATG16L1; Autophagosome; Biochemistry; BAG3; Proteostasis","score_opus":0.012131919890956319,"score_gpt":0.2764280679661382,"score_spread":0.2642961480751819,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135372426","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9841571,0.00664236,0.000039362934,0.0073703853,0.00035717827,0.0006747673,0.00014011352,0.00024427933,0.00037449482],"genre_scores_gemma":[0.98763144,0.0005368987,0.0003003569,0.005828378,0.00036374715,0.00014379862,0.00004548949,0.00008570338,0.005064176],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969944,0.00055939436,0.00049442885,0.00076286413,0.00054496864,0.0006439387],"domain_scores_gemma":[0.99729156,0.00076913566,0.00012981966,0.0011009481,0.00016779626,0.0005407313],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042484695,0.00044462437,0.0007533433,0.00022271364,0.00032445038,0.000112585425,0.00025994412,0.0002041145,0.00063573377],"category_scores_gemma":[0.00047413635,0.00031836657,0.0003196493,0.0007337267,0.00034788984,0.0001666946,0.00021663007,0.00027367537,0.0001815247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.024333095,0.0021719665,0.005940775,0.00037109098,0.0021968957,0.008592896,0.005366807,0.000064982414,0.91478044,0.006659799,0.0023671086,0.027154151],"study_design_scores_gemma":[0.007299059,0.00026203567,0.24792615,0.00016503662,0.0003430154,0.00032369923,0.00037975333,0.00013818717,0.736594,0.0005177922,0.005686578,0.00036466852],"about_ca_topic_score_codex":0.00011262037,"about_ca_topic_score_gemma":0.000021656931,"teacher_disagreement_score":0.24198538,"about_ca_system_score_codex":0.00009857095,"about_ca_system_score_gemma":0.000441353,"threshold_uncertainty_score":0.99992687},"labels":[],"label_agreement":null},{"id":"W3135393464","doi":"10.1016/j.biocel.2021.105964","title":"Chitosan/PCL nanoparticles can improve anti-neoplastic activity of 5-fluorouracil in head and neck cancer through autophagy activation","year":2021,"lang":"en","type":"article","venue":"The International Journal of Biochemistry & Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Réseau de Recherche en Santé Buccodentaire et Osseuse","keywords":"Autophagy; Fluorouracil; Chitosan; Nanoparticle; Head and neck; Cancer research; Cancer; Head and neck cancer; Chemistry; Nanotechnology; Medicine; Materials science; Internal medicine; Biochemistry; Surgery; Apoptosis","score_opus":0.012369678446940495,"score_gpt":0.2985146092297749,"score_spread":0.28614493078283443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135393464","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99556714,0.0014569636,0.000024861578,0.0023480186,0.00026277197,0.000049845818,0.000034334706,0.000003834585,0.00025223312],"genre_scores_gemma":[0.9984009,0.0008226045,0.00010842744,0.00032249352,0.00026855676,0.0000030631418,0.000011396398,0.000007089948,0.000055463835],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992261,0.00004292285,0.00030529377,0.00013603708,0.00016652765,0.00012310583],"domain_scores_gemma":[0.999184,0.00012748124,0.0003321266,0.00011584469,0.00019156607,0.000048967908],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000894415,0.00010428627,0.00024556002,0.000032381748,0.000023288158,0.000009748758,0.00014639231,0.00008742491,0.000085103056],"category_scores_gemma":[0.00010726837,0.00007416685,0.00007921958,0.00008022335,0.00011931272,0.000054421656,0.00005436766,0.00021240395,3.9972699e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005299245,0.00025894775,0.0066963863,0.000037573736,0.00017440227,0.00005173793,0.00019064416,0.000025380807,0.98729205,0.000027606897,0.000019328736,0.0046960018],"study_design_scores_gemma":[0.0016200563,0.00012352469,0.028490864,0.00013058177,0.000042460204,0.00012422113,0.000103928985,0.00008517255,0.9688273,0.00028731753,0.000104704006,0.000059852082],"about_ca_topic_score_codex":0.00014987541,"about_ca_topic_score_gemma":0.000011184547,"teacher_disagreement_score":0.021794477,"about_ca_system_score_codex":0.000064099644,"about_ca_system_score_gemma":0.00040886976,"threshold_uncertainty_score":0.30244362},"labels":[],"label_agreement":null},{"id":"W3135399731","doi":"10.1080/15548627.2021.1896925","title":"Coxsackievirus B3 targets TFEB to disrupt lysosomal function","year":2021,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"TFEB; Biology; Autophagy; Cell biology; Lysosome; Basic helix-loop-helix leucine zipper transcription factors; BAG3; Transcription factor; Genetics; Biochemistry; DNA-binding protein; Gene","score_opus":0.013235170617749193,"score_gpt":0.28616159319732076,"score_spread":0.27292642257957156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135399731","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97756195,0.0048992764,0.0014623714,0.001580655,0.0010533633,0.00034331722,0.00002446091,0.00028434204,0.0127902785],"genre_scores_gemma":[0.97800404,0.00008682817,0.0005177377,0.0093900245,0.00058389426,0.00004836288,0.00010391733,0.00004630946,0.011218913],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99847716,0.00005573985,0.0002805117,0.00044917697,0.00034370035,0.000393698],"domain_scores_gemma":[0.9988092,0.00003646567,0.00005224688,0.0005528954,0.00015593495,0.00039322657],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00009262151,0.00021327575,0.0003509833,0.00008598736,0.000119040895,0.00003342364,0.00009010231,0.00012289458,0.0039137374],"category_scores_gemma":[0.00009723868,0.0001987643,0.0001964253,0.00033930282,0.000039284067,0.000108945744,0.00006682013,0.00017348878,0.0018750491],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027355542,0.0027888215,0.012029734,0.00033793543,0.0015566737,0.0088048065,0.0014514978,0.000084976156,0.5762115,0.014060243,0.03456224,0.34537598],"study_design_scores_gemma":[0.0030751745,0.0006955397,0.50409704,0.00009964025,0.00031525738,0.0002560035,0.00014646782,0.00025201694,0.3011087,0.0014019626,0.18812041,0.0004318092],"about_ca_topic_score_codex":0.000027759332,"about_ca_topic_score_gemma":0.000007274974,"teacher_disagreement_score":0.4920673,"about_ca_system_score_codex":0.00007705267,"about_ca_system_score_gemma":0.00022599477,"threshold_uncertainty_score":0.9989021},"labels":[],"label_agreement":null},{"id":"W3135521810","doi":"10.1172/jci146821","title":"YAP/TFEB pathway promotes autophagic cell death and hypertrophic cardiomyopathy in lysosomal storage diseases","year":2021,"lang":"en","type":"letter","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"TFEB; Autophagy; Lysosome; Cell biology; Basic helix-loop-helix leucine zipper transcription factors; Transcription factor; Biology; Programmed cell death; Biochemistry; Enzyme; Gene; Apoptosis","score_opus":0.05679981380302977,"score_gpt":0.3237844179697605,"score_spread":0.2669846041667307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135521810","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89413226,0.009714957,0.000020953848,0.09465659,0.00090432446,0.0003573769,0.000038381844,0.000025238247,0.0001498943],"genre_scores_gemma":[0.72943395,0.0022724583,0.0013286795,0.25141898,0.014130501,0.000019616153,0.00029881235,0.000104417035,0.0009925907],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99536085,0.0008619049,0.0021350516,0.00047064485,0.0008416699,0.00032987603],"domain_scores_gemma":[0.99645114,0.0007465403,0.0014477179,0.0004130808,0.00043354052,0.00050796085],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0009396906,0.00039744226,0.001742923,0.000333523,0.000058069465,0.0000756517,0.00018349681,0.00095668837,0.00008135472],"category_scores_gemma":[0.0014223106,0.00031509378,0.00074089784,0.00024818085,0.00028515956,0.00023882107,0.000060099665,0.0030563707,0.0000088808965],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014119823,0.0021584674,0.6413486,0.004159386,0.0017686744,0.101795785,0.0007113231,0.000101428646,0.0053432584,0.00009660182,0.2274856,0.013618894],"study_design_scores_gemma":[0.013158608,0.0040491996,0.84574085,0.00508025,0.003073381,0.0016977956,0.00008993986,0.0014108212,0.0032770971,0.010231724,0.111048594,0.0011417171],"about_ca_topic_score_codex":0.000010395902,"about_ca_topic_score_gemma":7.477389e-7,"teacher_disagreement_score":0.20439227,"about_ca_system_score_codex":0.000106447456,"about_ca_system_score_gemma":0.0016990246,"threshold_uncertainty_score":0.99993014},"labels":[],"label_agreement":null},{"id":"W3135524488","doi":"10.1038/s42003-021-01830-x","title":"Insights on autophagosome–lysosome tethering from structural and biochemical characterization of human autophagy factor EPG5","year":2021,"lang":"en","type":"article","venue":"Communications Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; National Health and Medical Research Council; Canadian Institutes of Health Research; Office of Science; National Institutes of Health; Government of Canada; University of California, San Francisco; U.S. Department of Energy","keywords":"Autophagy; Cell biology; Lysosome; Autophagosome; Mitophagy; ATG8; Endosome; Biology; Chemistry; Biochemistry; Apoptosis; Intracellular","score_opus":0.03740804128363708,"score_gpt":0.33419095209212873,"score_spread":0.2967829108084917,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135524488","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961523,0.0026657593,0.00003383312,0.00045058338,0.00007863461,0.00012918166,0.00010453013,0.00005272945,0.00033248233],"genre_scores_gemma":[0.9968317,0.00052962,0.00052278815,0.00034002282,0.00006145511,0.00001634052,0.001618696,0.000014697253,0.000064654945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992209,0.00012915357,0.00027237838,0.00021284293,0.000055810764,0.00010893473],"domain_scores_gemma":[0.99854857,0.00012107009,0.00011361697,0.0010481001,0.00009210793,0.00007652045],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00001918337,0.00012306987,0.00028803764,0.000076381126,0.00012490057,0.00000836875,0.00021377647,0.00015296038,0.00019880741],"category_scores_gemma":[0.00004866167,0.00010728202,0.000059811413,0.00013329694,0.00027164145,0.000042313328,0.00017728536,0.0001813823,0.000007865303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023596227,0.00010134214,0.0032694805,0.000011906371,0.000093933406,0.0000029368218,0.00038966892,5.5991148e-8,0.9832936,0.009477381,0.000002724559,0.0033334051],"study_design_scores_gemma":[0.0007369593,0.00012324426,0.39746436,0.000050398965,0.000038122827,0.000006646379,0.00004009556,0.0002059513,0.59709334,0.0034429296,0.0006989654,0.000098992154],"about_ca_topic_score_codex":0.000016694152,"about_ca_topic_score_gemma":0.00000301678,"teacher_disagreement_score":0.3941949,"about_ca_system_score_codex":0.000029096906,"about_ca_system_score_gemma":0.000058817433,"threshold_uncertainty_score":0.43748337},"labels":[],"label_agreement":null},{"id":"W3136094005","doi":"10.1016/j.bbagen.2021.129894","title":"A mechanistic review of Parkin activation","year":2021,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - General Subjects","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Parkin; PINK1; Mitophagy; Ubiquitin ligase; Ubiquitin; Tensin; Cell biology; PTEN; Kinase; Biology; Autophagy; Chemistry; Genetics; Signal transduction; Parkinson's disease; PI3K/AKT/mTOR pathway; Medicine; Internal medicine; Apoptosis","score_opus":0.043773579591408714,"score_gpt":0.3650042025812661,"score_spread":0.3212306229898574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3136094005","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00483252,0.9917273,0.0000180099,0.00032887052,0.000302086,0.0018365801,0.00018924705,0.00010590908,0.00065950386],"genre_scores_gemma":[0.0017938585,0.9910904,0.00040385785,0.0019219242,0.0008289832,0.00026633125,0.00299176,0.00016665504,0.00053619576],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.99622583,0.0005181894,0.0011485273,0.00092710234,0.00068999565,0.0004903605],"domain_scores_gemma":[0.9969472,0.00018228644,0.0010835032,0.0012431929,0.00024948752,0.0002943193],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028568704,0.0008703581,0.0036549568,0.00024034567,0.00008150728,0.000034372457,0.00039637883,0.00045399784,0.00031812285],"category_scores_gemma":[0.00021114542,0.00068963366,0.0017480423,0.0010660014,0.00010678993,0.000091463415,0.00016267727,0.0005607214,0.00006637648],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016637902,0.002034513,8.40258e-8,0.43127778,0.0048550637,0.00020600212,0.00010803053,1.02718e-7,0.14789069,0.0028506694,0.016207865,0.39440283],"study_design_scores_gemma":[0.0008314421,0.000495712,0.000019235853,0.2912935,0.0077219894,0.000101683916,0.0000059973445,0.000007688849,0.21641682,0.0001625171,0.48184884,0.0010945778],"about_ca_topic_score_codex":0.000024367559,"about_ca_topic_score_gemma":6.1477937e-7,"teacher_disagreement_score":0.46564096,"about_ca_system_score_codex":0.00018415888,"about_ca_system_score_gemma":0.0015243776,"threshold_uncertainty_score":0.99955547},"labels":[],"label_agreement":null},{"id":"W3137603116","doi":"10.1016/j.isci.2021.102337","title":"The converging roles of Batten disease proteins in neurodegeneration and cancer","year":2021,"lang":"en","type":"review","venue":"iScience","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; Trent University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Nova Scotia Health Research Foundation","keywords":"Neurodegeneration; Batten disease; Disease; Neuroscience; Cancer; Computational biology; Medicine; Biology; Pathology; Internal medicine","score_opus":0.03454630868644935,"score_gpt":0.3524195952762164,"score_spread":0.31787328658976705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3137603116","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0028769644,0.99626344,0.0000118050175,0.00025541693,0.000085209555,0.00045207783,0.000013196048,0.000005218583,0.000036674763],"genre_scores_gemma":[0.0023345149,0.9971406,0.000012526068,0.00008409643,0.00005744915,0.00012725464,0.000006687252,0.000007874158,0.00022903498],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992237,0.000067495705,0.00019815515,0.00021821723,0.00017922359,0.00011322454],"domain_scores_gemma":[0.999519,0.000055210698,0.000102808975,0.00021493273,0.000032583554,0.000075482974],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014957612,0.000100146644,0.00035677187,0.00004559185,0.00006750913,0.000022059996,0.000098110984,0.000029625275,0.000016940288],"category_scores_gemma":[0.000075774,0.00005810147,0.000069874615,0.00023757402,0.00015213391,0.00004403684,0.000039913048,0.00009688036,9.325099e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004517776,0.00002158026,0.00018244363,0.0015011594,0.000010003126,0.00003130781,0.000056497443,0.0000024897024,0.000024932562,0.00027138615,0.000023393464,0.99787027],"study_design_scores_gemma":[0.00033648964,0.000042788502,0.0025339571,0.018699035,0.0003773762,0.000013932537,0.000052961106,0.00042266998,0.0001518873,0.000059025107,0.9771102,0.00019964468],"about_ca_topic_score_codex":0.00001841228,"about_ca_topic_score_gemma":0.000021672773,"teacher_disagreement_score":0.99767065,"about_ca_system_score_codex":0.000025079184,"about_ca_system_score_gemma":0.0006764981,"threshold_uncertainty_score":0.2369309},"labels":[],"label_agreement":null},{"id":"W3137966876","doi":"10.1080/15548627.2021.1898748","title":"AMPK-dependent phosphorylation is required for transcriptional activation of TFEB and TFE3","year":2021,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":231,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Terry Fox Research Institute; Kidney Foundation of Canada; Canadian Institutes of Health Research; Cancer Research Society","keywords":"TFEB; Biology; AMPK; Phosphorylation; Basic helix-loop-helix leucine zipper transcription factors; Cell biology; TFE3; Autophagy; Chromosomal translocation; Cancer research; Transcription factor; Protein kinase A; Biochemistry; Gene; DNA-binding protein; Apoptosis","score_opus":0.025355774617683905,"score_gpt":0.29316273861050834,"score_spread":0.26780696399282444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3137966876","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98934674,0.002224014,0.006116496,0.001191339,0.00014101129,0.000329044,0.000048255384,0.00003700917,0.0005660795],"genre_scores_gemma":[0.9950883,0.00016308116,0.0011135804,0.0010350428,0.000100229794,0.000035411573,0.00013428931,0.000016312364,0.0023137976],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992403,0.000017475615,0.00021852278,0.00020894661,0.00019699142,0.000117768206],"domain_scores_gemma":[0.99947834,0.000054383927,0.00007393165,0.00016162625,0.00016527412,0.00006641712],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008629447,0.000092566115,0.00019355648,0.000046022258,0.000051803727,0.000008813334,0.000027845002,0.00008409212,0.00048665903],"category_scores_gemma":[0.000039458864,0.00009110466,0.0000938289,0.000094091454,0.000039101375,0.00011056348,0.000007754972,0.00005174471,0.0000044648814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00068030827,0.00033568856,0.00077894964,0.00022269065,0.0002275791,0.000014814762,0.0010036055,0.000007460701,0.9533018,0.014157865,0.00066992355,0.0285993],"study_design_scores_gemma":[0.002729655,0.00016470006,0.07626169,0.00006141869,0.00009960589,0.00001790086,0.00010320194,0.0007435375,0.91051495,0.0051516155,0.004063007,0.000088738605],"about_ca_topic_score_codex":0.000012219922,"about_ca_topic_score_gemma":0.0000010285902,"teacher_disagreement_score":0.07548274,"about_ca_system_score_codex":0.000031034233,"about_ca_system_score_gemma":0.00014696458,"threshold_uncertainty_score":0.53285754},"labels":[],"label_agreement":null},{"id":"W3138648391","doi":"10.1038/s41436-021-01137-6","title":"Lysosomal cholesterol accumulation contributes to the movement phenotypes associated with NUS1 haploinsufficiency","year":2021,"lang":"en","type":"article","venue":"Genetics in Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"B.C. Women's Hospital & Health Centre","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences","keywords":"Haploinsufficiency; Phenotype; Cholesterol; Medicine; Biology; Genetics; Internal medicine; Bioinformatics; Cell biology; Gene","score_opus":0.03472479502700977,"score_gpt":0.3225504053463322,"score_spread":0.28782561031932247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3138648391","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97823906,0.0037060843,0.0025352987,0.013568407,0.0001965411,0.00053946645,0.0000072626235,0.000035215497,0.0011726867],"genre_scores_gemma":[0.9854557,0.00016808916,0.00017375899,0.013390975,0.0002172208,0.000038415114,0.0000756526,0.00002049776,0.0004596696],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99862725,0.00007613715,0.00030951024,0.00026906878,0.00044854087,0.00026950648],"domain_scores_gemma":[0.9990687,0.00012049909,0.00007321735,0.0003953218,0.00023114256,0.00011112553],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032050366,0.0001512985,0.0003024146,0.000090410846,0.000078540244,0.000013503481,0.00011934806,0.0000683021,0.00016946651],"category_scores_gemma":[0.00034559812,0.00009135587,0.000030914234,0.0005752002,0.00009654607,0.000018167593,0.000040992836,0.00016484928,0.000015720127],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016230984,0.0038617712,0.78353786,0.00017902374,0.0015199693,0.00092223764,0.011518944,0.015433241,0.11005148,0.0054116645,0.008111827,0.057828892],"study_design_scores_gemma":[0.00559569,0.0007896657,0.9703167,0.00053052325,0.0002034678,0.0000074337727,0.0006069562,0.002283251,0.015155014,0.0010509432,0.0033260107,0.0001343132],"about_ca_topic_score_codex":0.00002194674,"about_ca_topic_score_gemma":0.00018401416,"teacher_disagreement_score":0.18677889,"about_ca_system_score_codex":0.000101930054,"about_ca_system_score_gemma":0.00014503676,"threshold_uncertainty_score":0.37253842},"labels":[],"label_agreement":null},{"id":"W3138741565","doi":"10.1038/s41418-021-00766-3","title":"Characterization of a natural variant of human NDP52 and its functional consequences on mitophagy","year":2021,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Genentech; Deutsche Forschungsgemeinschaft; Wellcome Trust; Ontario Genomics Institute; Indian Council of Agricultural Research; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Ontario Genomics; Fundação de Amparo à Pesquisa do Estado de São Paulo; Genome Canada; Danish e-Infrastructure Cooperation; McGill University; Danmarks Grundforskningsfond; Bayer; Ministero della Salute; Pfizer","keywords":"Mitophagy; PINK1; Population; Mitochondrion; Biology; Genetics; Medicine; Autophagy; Apoptosis","score_opus":0.017687782705054018,"score_gpt":0.24553436829635641,"score_spread":0.2278465855913024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3138741565","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998475,0.00088391796,0.00011476089,0.000050325743,0.00010137541,0.00009162703,0.00001587399,0.000007039926,0.00026006385],"genre_scores_gemma":[0.99885124,0.0002483581,0.000012683642,0.000085525695,0.000047514284,0.0000035964306,0.00036332005,0.000004129444,0.00038365938],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99955684,0.000025006573,0.00014004405,0.000117078984,0.000106866544,0.00005418117],"domain_scores_gemma":[0.99970007,0.000020535848,0.00008986549,0.000058218837,0.000089668145,0.000041657702],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000023986397,0.00006304521,0.00013691325,0.00004620568,0.000038048045,0.0000065281383,0.0000104735855,0.000041164993,0.00011895494],"category_scores_gemma":[0.000012219049,0.000052354295,0.000028508395,0.00004436125,0.00002471492,0.000042527885,0.00000785682,0.000039923958,7.1519145e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011574723,0.00014575582,0.007532619,0.00014635241,0.00003161653,0.000008113747,0.0001013819,1.5560775e-7,0.98753965,0.0038785296,0.0000029854584,0.00049710803],"study_design_scores_gemma":[0.000686083,0.00009365436,0.47974023,0.000037941896,0.000042141142,0.0000065716868,0.000013322086,0.00018263402,0.5188537,0.00031098694,0.000004616302,0.000028088929],"about_ca_topic_score_codex":0.0000026142966,"about_ca_topic_score_gemma":6.0818286e-7,"teacher_disagreement_score":0.4722076,"about_ca_system_score_codex":0.0000056542385,"about_ca_system_score_gemma":0.00003402753,"threshold_uncertainty_score":0.21349463},"labels":[],"label_agreement":null},{"id":"W3144365585","doi":"10.1101/2021.04.08.439013","title":"Snazarus and its human ortholog SNX25 regulate autophagic flux by affecting VAMP8 endocytosis","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Université de Sherbrooke","keywords":"Sorting nexin; Autophagy; Cell biology; Endocytosis; Biology; Lysosome; Flux (metallurgy); Endosome; Chemistry; Cell; Intracellular; Apoptosis; Biochemistry","score_opus":0.01458831699132562,"score_gpt":0.25197083511051965,"score_spread":0.23738251811919403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3144365585","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97648907,0.020416046,0.00008118068,0.00023445356,0.0007149791,0.001122846,0.00017343089,0.0007185572,0.000049465434],"genre_scores_gemma":[0.9965309,0.0009937644,0.00067917054,0.0006904829,0.00056207256,0.00020436336,0.0000069758744,0.00023682657,0.000095473675],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99593747,0.0002602455,0.00073987147,0.0016537479,0.0005531293,0.00085555995],"domain_scores_gemma":[0.9967892,0.00009946659,0.00052240014,0.0015015651,0.0004380384,0.00064931676],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005774522,0.00089540635,0.0012859923,0.00030434423,0.00039253538,0.00026778004,0.0003527069,0.00086721283,0.0004432038],"category_scores_gemma":[0.00022326109,0.00095100654,0.00034737063,0.00044966792,0.00015485808,0.00018434053,0.0006042638,0.0012805216,0.00004713684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006283214,0.00032803076,0.008052448,0.0011172757,0.0007551804,0.0010320867,0.000033368706,0.0000052487144,0.98786414,0.00021592113,0.00052383775,0.000009626819],"study_design_scores_gemma":[0.001923475,0.00015802651,0.19269684,0.0009650723,0.00073239824,6.0452675e-7,0.00000976643,0.00015673657,0.80125237,0.0000037001141,0.001177396,0.0009236378],"about_ca_topic_score_codex":0.00003303349,"about_ca_topic_score_gemma":0.0000012415312,"teacher_disagreement_score":0.1866118,"about_ca_system_score_codex":0.00029064043,"about_ca_system_score_gemma":0.0005722693,"threshold_uncertainty_score":0.99929404},"labels":[],"label_agreement":null},{"id":"W3146301611","doi":"10.1016/j.pharmthera.2021.107848","title":"Targeting autophagy in ischemic stroke: From molecular mechanisms to clinical therapeutics","year":2021,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":322,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"Canada Research Chairs; National Institutes of Health; Bundesministerium für Bildung, Wissenschaft und Forschung; University of Wyoming; National Natural Science Foundation of China; Austrian Science Fund; Agence Nationale de la Recherche; National Key Research and Development Program of China; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Österreichischen Akademie der Wissenschaften; American Diabetes Association","keywords":"Autophagy; Autophagosome; Programmed cell death; Context (archaeology); Cell biology; Stroke (engine); Mechanism (biology); Biology; Cause of death; Neuroscience; Organelle; Medicine; Bioinformatics; Apoptosis; Disease; Pathology; Genetics","score_opus":0.10068779652878013,"score_gpt":0.46007897810654014,"score_spread":0.35939118157776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3146301611","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018577375,0.99028116,0.0019804426,0.0005753062,0.0025541754,0.0020753513,0.00020690067,0.00018616904,0.00028276347],"genre_scores_gemma":[0.00043735743,0.9570567,0.0035526005,0.036400057,0.001034853,0.00034543214,0.000575742,0.00028926512,0.0003079674],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99393046,0.0012436492,0.0019710155,0.0013387713,0.00051142933,0.0010046668],"domain_scores_gemma":[0.9971744,0.00078907696,0.0005543601,0.00083504943,0.0001741744,0.0004729655],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00076718716,0.0010437464,0.0039481674,0.00037839683,0.00009216878,0.00004459759,0.00072714954,0.0013512543,0.0013708534],"category_scores_gemma":[0.000015054956,0.00094362046,0.0013359247,0.0007023352,0.00016272035,0.000060201575,0.00029362028,0.0023741622,0.00026511512],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024799304,0.0020443755,0.00003327162,0.0013814634,0.011943363,0.0027104146,0.0002433857,0.00001338442,0.01879139,0.000083259074,0.0015964657,0.9609112],"study_design_scores_gemma":[0.002456144,0.00030715772,0.000008406744,0.0018427324,0.013865927,0.000050062044,0.000052216667,0.00021684045,0.0063071,0.000097460805,0.9740307,0.000765305],"about_ca_topic_score_codex":0.0000126032,"about_ca_topic_score_gemma":0.0000012993414,"teacher_disagreement_score":0.97243416,"about_ca_system_score_codex":0.00034551654,"about_ca_system_score_gemma":0.0014233731,"threshold_uncertainty_score":0.9999452},"labels":[],"label_agreement":null},{"id":"W3147413410","doi":"10.1139/bcb-2021-0028","title":"Induction of PDCD4 by albumin in proximal tubule epithelial cells potentiates proteinuria-induced dysfunctional autophagy by negatively targeting Atg5","year":2021,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"ATG5; Autophagy; Downregulation and upregulation; Blot; BECN1; Cell biology; Programmed cell death; Chemistry; Biology; Cancer research; Molecular biology; Apoptosis; Biochemistry; Gene","score_opus":0.006727668953058346,"score_gpt":0.22792471655027416,"score_spread":0.2211970475972158,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3147413410","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99539983,0.0034857017,0.000027019028,0.00016207117,0.00012568152,0.00020530305,0.00012519372,0.000019809753,0.00044939405],"genre_scores_gemma":[0.99737066,0.00014624426,0.00019849444,0.00010085938,0.00015875495,0.000036489895,0.00055480516,0.0000130483,0.00142062],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989133,0.00007210401,0.0003037852,0.00039327092,0.00008842133,0.00022912679],"domain_scores_gemma":[0.99953383,0.000033797936,0.0001366836,0.00012692221,0.00007440461,0.00009434825],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012228862,0.00017023786,0.0002810145,0.000026428708,0.000052023603,0.000006523742,0.00005272219,0.00030438465,0.0003131157],"category_scores_gemma":[0.0000415652,0.0001565032,0.00006692046,0.00012323174,0.00012749765,0.000032601638,0.000037612925,0.0002024695,0.000004187342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028346293,0.0004349005,0.00062515686,0.0001590934,0.000051178373,0.000016934124,0.000058039146,3.9030817e-7,0.99620557,0.000010385197,0.00079615734,0.0013587134],"study_design_scores_gemma":[0.00184774,0.00022149569,0.0005546807,0.000033042616,0.000031458614,0.000014307038,0.00018682255,0.00003581303,0.99525434,0.00013087876,0.0015464346,0.00014298409],"about_ca_topic_score_codex":0.00003925015,"about_ca_topic_score_gemma":3.3062304e-7,"teacher_disagreement_score":0.0033394576,"about_ca_system_score_codex":0.000031345684,"about_ca_system_score_gemma":0.00016705207,"threshold_uncertainty_score":0.63820153},"labels":[],"label_agreement":null},{"id":"W3148521881","doi":"10.3389/fonc.2021.555614","title":"Autophagic Heterogeneity in Gastric Adenocarcinoma","year":2021,"lang":"en","type":"article","venue":"Frontiers in Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Autophagy; Biology; Adenocarcinoma; Tissue microarray; Carcinogenesis; Immunohistochemistry; Pathology; Cancer research; Cancer; Apoptosis; Medicine; Immunology; Genetics","score_opus":0.018428727185692804,"score_gpt":0.3123363753729541,"score_spread":0.2939076481872613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3148521881","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9785425,0.014424658,0.00066748203,0.0009627538,0.0010600891,0.00020727157,0.0000042923293,0.0000341287,0.004096796],"genre_scores_gemma":[0.99019504,0.0005535398,0.0063909725,0.002101903,0.00013331593,0.000040619834,0.0000300143,0.000018156956,0.0005364397],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987156,0.00017315653,0.0002985635,0.00033418453,0.00012278033,0.00035575716],"domain_scores_gemma":[0.99945647,0.000038777765,0.00005148472,0.00029011993,0.000035841596,0.00012729611],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016382145,0.0001291984,0.00047408493,0.0002648233,0.000021565176,0.000004881241,0.000094314375,0.00020711092,0.00024826775],"category_scores_gemma":[0.000077471545,0.00013201978,0.000093017756,0.00050885585,0.000078954596,0.000043781707,0.000046632933,0.0003036588,0.000032054213],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033544897,0.00072621356,0.9560122,0.000032923956,0.00006401768,0.008187319,0.00030143053,0.000020761343,0.0009550553,0.00008297211,0.006278565,0.02700312],"study_design_scores_gemma":[0.0047268546,0.0003727465,0.97378206,0.00003477791,0.00003075821,0.0003780397,0.00040791382,0.00062188914,0.0038828473,0.0013148171,0.014315104,0.00013219597],"about_ca_topic_score_codex":0.000019013412,"about_ca_topic_score_gemma":0.00005351651,"teacher_disagreement_score":0.026870925,"about_ca_system_score_codex":0.0005074348,"about_ca_system_score_gemma":0.000566658,"threshold_uncertainty_score":0.5383611},"labels":[],"label_agreement":null},{"id":"W3150373925","doi":"10.1007/s10571-021-01082-7","title":"NIX Mediates Mitophagy in Spinal Cord Injury in Rats by Interacting with LC3","year":2021,"lang":"en","type":"article","venue":"Cellular and Molecular Neurobiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Natural Science Foundation of China","keywords":"Mitophagy; Autophagy; Downregulation and upregulation; Neuroprotection; Cell biology; Mitochondrion; Spinal cord injury; Autophagosome; Spinal cord; Neuroscience; Biology; Chemistry; Apoptosis; Gene; Biochemistry","score_opus":0.0073095152274196265,"score_gpt":0.269291487752173,"score_spread":0.26198197252475336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3150373925","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99387,0.005035653,0.00010802741,0.00040142954,0.00016379495,0.00016478078,0.000005089944,0.000017509903,0.00023372336],"genre_scores_gemma":[0.99731433,0.00034101095,0.000100688136,0.0019723854,0.000033191693,0.000015481826,0.000107662825,0.000023925,0.00009134345],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988955,0.00015593924,0.00022274302,0.00039023254,0.00006161034,0.00027397033],"domain_scores_gemma":[0.99957365,0.00004396909,0.000051416664,0.00019890822,0.00003261092,0.00009942919],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007271799,0.00016623356,0.00032278357,0.00010503543,0.000021972057,0.000010632461,0.000057285044,0.00010921289,0.0000563487],"category_scores_gemma":[0.0000617638,0.00014495723,0.00004599167,0.00019107119,0.000090322406,0.00003366065,0.000051902774,0.00029541113,0.000006340705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012890052,0.00017456339,0.0078937635,0.000041801093,0.00003165372,0.004967885,0.000048933358,0.0000013293255,0.98206407,0.000056542423,0.000090732894,0.0033397325],"study_design_scores_gemma":[0.0017411057,0.0014337723,0.0059219752,0.00012261077,0.000029326296,0.00023351323,0.000084241685,0.000034209763,0.9877135,0.00009323349,0.0024245442,0.00016796782],"about_ca_topic_score_codex":0.000021580841,"about_ca_topic_score_gemma":0.000009848012,"teacher_disagreement_score":0.005649442,"about_ca_system_score_codex":0.000017003389,"about_ca_system_score_gemma":0.000081423954,"threshold_uncertainty_score":0.59111845},"labels":[],"label_agreement":null},{"id":"W3152529170","doi":"10.15252/emmm.202013258","title":"Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1‐dependent TFEB/TFE3 regulation","year":2021,"lang":"en","type":"article","venue":"EMBO Molecular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; SickKids Foundation; Toronto Western Hospital; Hospital for Sick Children; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institutes of Health; Universitair Medisch Centrum Utrecht; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; ZonMw; Deutsche Forschungsgemeinschaft","keywords":"Library science; Gerontology; Medicine","score_opus":0.01075009396844923,"score_gpt":0.25605966455509965,"score_spread":0.24530957058665043,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3152529170","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9538348,0.008947645,0.023827635,0.005499059,0.00059151783,0.00042877655,0.0000067911915,0.00011286611,0.0067509445],"genre_scores_gemma":[0.9903745,0.00029699822,0.00020746005,0.006203505,0.0005592945,0.000022299648,0.00021494365,0.00004314995,0.0020778484],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99821985,0.00015467165,0.0003298715,0.00051149435,0.00054070074,0.00024342649],"domain_scores_gemma":[0.99891084,0.00003700428,0.00010247506,0.0004467275,0.00023003042,0.0002729204],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00021673,0.00023403479,0.00038973326,0.00012040288,0.000105815605,0.000017158389,0.000045875313,0.00012761149,0.0010179871],"category_scores_gemma":[0.00019862445,0.00019849434,0.00006954795,0.00030065735,0.00011708756,0.0000915921,0.000047158243,0.00022697839,0.000030459727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003379359,0.0001911046,0.0008243051,0.000079788064,0.0002581088,0.0013749042,0.0004470446,0.000037711,0.9785056,0.007916406,0.0015718143,0.008455239],"study_design_scores_gemma":[0.017389541,0.0022920556,0.3457056,0.0008878811,0.0016557691,0.001143338,0.00069584564,0.0018233862,0.60400593,0.016155703,0.0075270645,0.00071787514],"about_ca_topic_score_codex":0.000020267464,"about_ca_topic_score_gemma":0.0000040066034,"teacher_disagreement_score":0.3744997,"about_ca_system_score_codex":0.000050773877,"about_ca_system_score_gemma":0.0001390162,"threshold_uncertainty_score":0.9998952},"labels":[],"label_agreement":null},{"id":"W3156557484","doi":"10.1038/s41419-021-03660-5","title":"Mitochondrial quality control protects photoreceptors against oxidative stress in the H2O2-induced models of retinal degeneration diseases","year":2021,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China; University of Ottawa","keywords":"Mitophagy; Cell biology; Mitochondrion; Neuroprotection; Oxidative stress; PINK1; Proteostasis; Retinal degeneration; Biology; Programmed cell death; Autophagy; Chemistry; Biochemistry; Pharmacology; Apoptosis; Retinal","score_opus":0.025819591037290167,"score_gpt":0.2834026461643412,"score_spread":0.25758305512705104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3156557484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99509406,0.0024637615,0.0003688571,0.00022785684,0.00009678601,0.00091043994,0.00030058384,0.00001832031,0.0005193386],"genre_scores_gemma":[0.9980619,0.00012424217,0.000069674985,0.0010205688,0.00020311633,0.0001535817,0.00028882214,0.000012763536,0.00006534804],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985652,0.00033000548,0.0002880668,0.00031037958,0.00031403248,0.00019229764],"domain_scores_gemma":[0.99888146,0.00012256383,0.00010959513,0.00032157838,0.00016501115,0.00039981699],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000095440315,0.00016689916,0.00027985242,0.00004764404,0.000082626204,0.000027655913,0.00007397704,0.000058382695,0.000049486836],"category_scores_gemma":[0.00029778507,0.00012035535,0.00012923483,0.00013258186,0.00006023722,0.00010509122,0.000017657168,0.00011655495,0.000001626739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02044562,0.009246577,0.12801932,0.0020675792,0.00029823664,0.0014222554,0.0042570676,0.0008573689,0.8216255,0.0058374084,0.0009376923,0.004985419],"study_design_scores_gemma":[0.02585714,0.00064578484,0.260454,0.0005788081,0.0009420818,0.0000048999923,0.0026250728,0.0106808515,0.68810946,0.009257188,0.00009688643,0.0007478061],"about_ca_topic_score_codex":0.000030009982,"about_ca_topic_score_gemma":0.0000071790428,"teacher_disagreement_score":0.13351597,"about_ca_system_score_codex":0.000026175136,"about_ca_system_score_gemma":0.00048593793,"threshold_uncertainty_score":0.49079487},"labels":[],"label_agreement":null},{"id":"W3156833871","doi":"10.1016/j.bbamcr.2021.119041","title":"Interactions between reactive oxygen species and autophagy","year":2021,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":175,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Reactive oxygen species; Cell biology; Oxidative stress; Mitophagy; Mitochondrial ROS; Mitochondrion; Chemistry; Oxidative phosphorylation; Superoxide; Programmed cell death; Biochemistry; Biology; Apoptosis","score_opus":0.06174409104779925,"score_gpt":0.3782022329232635,"score_spread":0.3164581418754642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3156833871","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9683881,0.0007350047,0.000076565,0.004911966,0.00007941018,0.00046894987,0.00007443875,0.000083746425,0.025181813],"genre_scores_gemma":[0.9920874,0.0006806433,0.0005060451,0.0005495228,0.00032407022,0.000052558997,0.00033866192,0.000076485885,0.005384584],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99686986,0.00048403934,0.00032077628,0.00079730665,0.0008770062,0.0006509831],"domain_scores_gemma":[0.9977555,0.00035671267,0.0000884024,0.00085589563,0.00047457623,0.00046888614],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035105,0.00030204133,0.00046766378,0.00031086185,0.00028818322,0.00015562834,0.00024387882,0.0001618949,0.00028965765],"category_scores_gemma":[0.0001500336,0.00028638783,0.00025795394,0.0007953698,0.0004073185,0.00015592795,0.00036877833,0.0009533377,0.00013875088],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001744226,0.0005039284,0.00002071706,0.00009253967,0.0003492202,0.0005025118,0.0005031077,1.9270473e-7,0.99488604,0.0007098028,0.0013555251,0.00090197154],"study_design_scores_gemma":[0.0010013714,0.00029253733,0.021193303,0.00009445998,0.00013763802,0.000025419484,0.00044527533,0.00003483075,0.9666718,0.0010349546,0.008816837,0.000251551],"about_ca_topic_score_codex":0.000040333794,"about_ca_topic_score_gemma":0.0000022517004,"teacher_disagreement_score":0.02821424,"about_ca_system_score_codex":0.00013702996,"about_ca_system_score_gemma":0.0005873954,"threshold_uncertainty_score":0.9999588},"labels":[],"label_agreement":null},{"id":"W3156871550","doi":"10.1016/j.bj.2021.04.002","title":"epg5 knockout leads to the impairment of reproductive success and courtship behaviour in a zebrafish model of autophagy-related diseases","year":2021,"lang":"en","type":"article","venue":"Biomedical Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"School of Medicine, New York University; Westfälische Wilhelms-Universität Münster; Università degli Studi di Padova; Ministero della Salute; Associazione Italiana per la Ricerca sul Cancro; Fondazione Telethon; York University; CureSearch for Children's Cancer","keywords":"Zebrafish; Courtship; Autophagy; Biology; Knockout mouse; Zoology; Neuroscience; Genetics","score_opus":0.013801493282337512,"score_gpt":0.2966508598356455,"score_spread":0.28284936655330795,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3156871550","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894129,0.0041739326,0.00016072452,0.0057330336,0.00017796924,0.00022676477,0.00006204244,0.000011294729,0.00004134164],"genre_scores_gemma":[0.99868715,0.00024198578,0.00023413659,0.000412818,0.00018345725,0.00000983252,0.000014220352,0.00001519595,0.00020122564],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9981728,0.00012545963,0.0005991195,0.00025692722,0.0006043386,0.00024132499],"domain_scores_gemma":[0.99880344,0.00006564013,0.0001837279,0.00030092592,0.00020951136,0.00043677932],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048688485,0.00013550151,0.00041629057,0.00016265569,0.00005915605,0.000014269789,0.00014454135,0.00009843378,0.00022403857],"category_scores_gemma":[0.00028639304,0.00008825604,0.00014193742,0.00039219696,0.00027932634,0.00006460096,0.00008395561,0.0003251232,0.0000020433695],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006891429,0.021846782,0.6420181,0.0009806425,0.0023124567,0.0071712295,0.018508768,0.001063042,0.22335052,0.0018830121,0.023628786,0.050345264],"study_design_scores_gemma":[0.005526916,0.0009972081,0.9553103,0.0008012138,0.0005532062,0.0008763074,0.00082384044,0.002489244,0.030117542,0.0021099187,0.0001890686,0.00020523985],"about_ca_topic_score_codex":0.000016995962,"about_ca_topic_score_gemma":0.0000034754894,"teacher_disagreement_score":0.31329224,"about_ca_system_score_codex":0.00005727157,"about_ca_system_score_gemma":0.00062509556,"threshold_uncertainty_score":0.3598977},"labels":[],"label_agreement":null},{"id":"W3158743587","doi":"10.30476/mejc.2021.85836.1307","title":"Autophagy Flux Correlates with Upregulation of AKT-1 in RAS Mutated Colon Cancer Cells","year":2021,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Protein kinase B; Autophagy; Oncogene; Cancer research; PI3K/AKT/mTOR pathway; Downregulation and upregulation; Sequestosome 1; Biology; Cancer; Phosphorylation; Cell biology; Signal transduction; Cell cycle; Apoptosis; Biochemistry; Gene; Genetics","score_opus":0.13610471941489038,"score_gpt":0.5356980503065258,"score_spread":0.39959333089163546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3158743587","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96944326,0.027873598,0.00007301443,0.0001399195,0.00035381634,0.00054630346,0.00004217368,0.000027784079,0.0015001072],"genre_scores_gemma":[0.9922076,0.0058831754,0.0001225389,0.0003143649,0.00008668866,0.000045994202,0.00005757344,0.000052741638,0.0012293519],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976864,0.00020975353,0.0008109827,0.00038007082,0.00060403376,0.00030876359],"domain_scores_gemma":[0.9979272,0.00020856032,0.0007098355,0.00041273897,0.0005197117,0.0002219487],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004185685,0.00027169654,0.00092260353,0.00047797817,0.000081842634,0.00014424516,0.0005332325,0.00014869915,0.020085946],"category_scores_gemma":[0.00008438255,0.00022899722,0.00014864483,0.0012751112,0.00014720368,0.0007578209,0.00017517764,0.00034448583,0.000009713921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015408789,0.0006873978,0.33091527,0.00020631203,0.000500848,0.0004943073,0.0004066786,0.0021250043,0.65048933,0.00003570259,0.0045194565,0.008078829],"study_design_scores_gemma":[0.0018664547,0.000024701822,0.46779376,0.0008819452,0.00015888603,0.000019367371,0.0000660272,0.00036250424,0.52760077,0.00059316703,0.00047596236,0.00015646503],"about_ca_topic_score_codex":0.0008990115,"about_ca_topic_score_gemma":0.00013877399,"teacher_disagreement_score":0.1368785,"about_ca_system_score_codex":0.00014682657,"about_ca_system_score_gemma":0.0006560452,"threshold_uncertainty_score":0.9808098},"labels":[],"label_agreement":null},{"id":"W3159276241","doi":"10.1007/s13402-021-00607-y","title":"Differential regulation of autophagy by STAU1 in alveolar rhabdomyosarcoma and non‐transformed skeletal muscle cells","year":2021,"lang":"en","type":"article","venue":"Cellular Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Università degli Studi di Padova; Cancer Research Society","keywords":"Autophagy; Alveolar rhabdomyosarcoma; BECN1; Cell biology; ATG16L1; Downregulation and upregulation; Skeletal muscle; Biology; Gene silencing; Apoptosis; Cancer research; Endocrinology; Rhabdomyosarcoma; Biochemistry; Gene; Medicine; Pathology","score_opus":0.006762949337392718,"score_gpt":0.25380543624253327,"score_spread":0.24704248690514055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3159276241","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944306,0.0019663253,0.0017234326,0.00032234157,0.00021108228,0.0002956783,0.00001845003,0.00001988482,0.0010121767],"genre_scores_gemma":[0.998228,0.00031174198,0.00032233287,0.00019382173,0.00007709533,0.000015417541,0.00018523884,0.00002173463,0.0006446007],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988045,0.00011525184,0.00036952549,0.00028717128,0.00016726342,0.00025630576],"domain_scores_gemma":[0.99940044,0.000077327764,0.00009051202,0.00023378564,0.00006483275,0.00013312406],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00010534984,0.00014928008,0.00047242537,0.00009103296,0.000035526617,0.0000058051396,0.000059383558,0.0002333456,0.0011264604],"category_scores_gemma":[0.000015363748,0.00014620647,0.00010943776,0.00015775044,0.00015255583,0.000058197442,0.000031487554,0.0001864756,0.00001039737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014002385,0.0006779197,0.00084605755,0.00012225339,0.00006654013,0.00026037835,0.00044718536,0.0000022749368,0.9837191,0.00013334326,0.00033641775,0.013248516],"study_design_scores_gemma":[0.005156438,0.00051401975,0.08514727,0.000040523504,0.00010980903,0.000017093744,0.00014671976,0.0008648307,0.8966159,0.0003667551,0.010887748,0.00013285427],"about_ca_topic_score_codex":0.000029508526,"about_ca_topic_score_gemma":0.000016280752,"teacher_disagreement_score":0.08710315,"about_ca_system_score_codex":0.00007953037,"about_ca_system_score_gemma":0.00024808955,"threshold_uncertainty_score":0.9997867},"labels":[],"label_agreement":null},{"id":"W3159525369","doi":"10.3390/cells10051054","title":"Manifestations of Age on Autophagy, Mitophagy and Lysosomes in Skeletal Muscle","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mitophagy; Autophagy; Lysosome; Sarcopenia; Cell biology; Organelle; Biology; Mitochondrion; Biochemistry; Enzyme; Anatomy; Apoptosis","score_opus":0.03698617028895981,"score_gpt":0.3475333684877263,"score_spread":0.3105471981987665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3159525369","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0049383636,0.9916347,0.0000015380714,0.000011436083,0.00019514807,0.0005257171,0.00006258796,0.00002046573,0.002610036],"genre_scores_gemma":[0.001074209,0.9957999,0.00012080077,0.000090030655,0.00012137285,0.000044449924,0.0001915989,0.00004425673,0.0025133942],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99873847,0.00010173159,0.00045996948,0.00033467877,0.00017723456,0.000187897],"domain_scores_gemma":[0.9991189,0.0001968847,0.00016434857,0.00037958054,0.000027795193,0.00011247256],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008618299,0.00026386286,0.0012834996,0.00023265473,0.00002274404,0.000011268114,0.000087678614,0.00020745161,0.00035139173],"category_scores_gemma":[0.000024347937,0.00022112417,0.00033417696,0.00024575175,0.00008576945,0.000026447244,0.00003716414,0.00026158371,0.00004956589],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000036356657,0.00045285252,0.0000031693942,0.013550303,0.00020812539,0.0063112937,0.00015577128,5.596278e-7,0.000109426685,0.00038851393,0.00063359045,0.97818273],"study_design_scores_gemma":[0.0006831611,0.00016871006,0.0005900656,0.013112964,0.0006411866,0.00013204284,0.00004868448,0.0000026842226,0.0004832597,0.00009081714,0.983789,0.00025738677],"about_ca_topic_score_codex":0.000011774488,"about_ca_topic_score_gemma":0.0000026011317,"teacher_disagreement_score":0.9831554,"about_ca_system_score_codex":0.000048713526,"about_ca_system_score_gemma":0.0002463747,"threshold_uncertainty_score":0.9017182},"labels":[],"label_agreement":null},{"id":"W3160296053","doi":"10.1101/2021.05.20.444917","title":"V-ATPase is a universal regulator of LC3 associated phagocytosis and non-canonical autophagy","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; Cancer Research UK","keywords":"Autophagy; ATG16L1; Cell biology; Regulator; Endocytosis; Phagocytosis; Chemistry; Biology; ATPase; Biochemistry; Gene; Receptor; Enzyme","score_opus":0.01101845142879681,"score_gpt":0.23273678260387154,"score_spread":0.22171833117507472,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3160296053","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941693,0.0036189877,0.00013950771,0.000305661,0.00045499275,0.00068559643,0.00038119822,0.00022081316,0.000023969784],"genre_scores_gemma":[0.9966998,0.00085228414,0.0012677099,0.0006895604,0.0002504368,0.00005642572,0.0000022665533,0.00014571994,0.00003580151],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99692404,0.0001450135,0.0006927575,0.0010884437,0.0006037762,0.00054598885],"domain_scores_gemma":[0.9966358,0.000091876354,0.0005605682,0.0013883654,0.0007205511,0.0006028607],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038095153,0.00061403617,0.0013183276,0.000287399,0.00011193176,0.000085745436,0.0003045842,0.00091654406,0.00036941026],"category_scores_gemma":[0.00022703882,0.0006608347,0.00039861875,0.0005651416,0.0002935182,0.00012872071,0.00046079696,0.00079446385,0.000013376196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004480235,0.001411124,0.024104882,0.0014284528,0.0029648861,0.0012028936,0.00010570817,0.000006538027,0.967117,0.00027086033,0.0009309165,0.000008709676],"study_design_scores_gemma":[0.003132829,0.00018812543,0.391403,0.0011016346,0.0010487202,9.3110216e-8,0.000014092672,0.00055094046,0.6014713,0.0000017696668,0.00049793185,0.0005895363],"about_ca_topic_score_codex":0.000100589255,"about_ca_topic_score_gemma":0.0000019550223,"teacher_disagreement_score":0.36729813,"about_ca_system_score_codex":0.00039039875,"about_ca_system_score_gemma":0.0023784821,"threshold_uncertainty_score":0.9995843},"labels":[],"label_agreement":null},{"id":"W3161047942","doi":"10.21203/rs.3.rs-42392/v1","title":"Autophagic Flux Impairment Exacerbates Myocardial Ischemia-Reperfusion Injury in Experimental Diabetes Through Atg5/LAMP2 Cleavage by Calpains","year":2020,"lang":"en","type":"preprint","venue":"Research Square (Research Square)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China; Lawson Health Research Institute","keywords":"Autophagy; Calpain; ATG5; Reperfusion injury; Ischemia; Flux (metallurgy); Internal medicine; Cleavage (geology); Cardiology; Medicine; Cell biology; Chemistry; Biology; Apoptosis; Biochemistry; Enzyme","score_opus":0.06922112503568068,"score_gpt":0.4265982760257318,"score_spread":0.35737715099005113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3161047942","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9547011,0.023102026,0.000023049264,0.0063386485,0.0005074078,0.008579382,0.00078621344,0.0004663632,0.0054957615],"genre_scores_gemma":[0.98282003,0.0050394624,0.00026137335,0.00063133164,0.0019503591,0.0035938013,0.0036455377,0.00042712537,0.001631004],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.97582084,0.004938492,0.0017627971,0.0036691895,0.009002056,0.004806628],"domain_scores_gemma":[0.9914096,0.0017601227,0.00026606245,0.0030416583,0.0012701198,0.0022524311],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"category_scores_codex":[0.008349208,0.001491667,0.0023927924,0.0016787468,0.0010256221,0.0006118665,0.002101095,0.001832144,0.0046349545],"category_scores_gemma":[0.0017574716,0.0013947912,0.001205575,0.002558641,0.0019174779,0.00052534585,0.0060011097,0.011588992,0.0011366393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0047569885,0.0071596475,0.014889952,0.004732519,0.00096072094,0.0022523995,0.010889381,0.000039954863,0.57434833,0.00035309084,0.3750665,0.004550522],"study_design_scores_gemma":[0.0061062276,0.006923313,0.005224266,0.0037634156,0.00006549239,0.000011928388,0.0058231032,0.002192973,0.9366303,0.0032467775,0.028517874,0.0014943352],"about_ca_topic_score_codex":0.0019337689,"about_ca_topic_score_gemma":0.0000191659,"teacher_disagreement_score":0.36228198,"about_ca_system_score_codex":0.0041717826,"about_ca_system_score_gemma":0.003883528,"threshold_uncertainty_score":0.9997833},"labels":[],"label_agreement":null},{"id":"W3163539696","doi":"10.1016/j.lfs.2021.119596","title":"Beclin-1, an autophagy-related protein, is associated with the disease severity of COVID-19","year":2021,"lang":"en","type":"article","venue":"Life Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Procalcitonin; Medicine; Ferritin; BECN1; Biomarker; Gastroenterology; Fibrinogen; Internal medicine; C-reactive protein; Disease; Severity of illness; D-dimer; Immunology; Inflammation; Autophagy; Sepsis; Biology","score_opus":0.032768454274318966,"score_gpt":0.3249037848847116,"score_spread":0.29213533061039265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3163539696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9827689,0.001452503,0.000034692213,0.014453517,0.000056726676,0.00035023745,0.000048186368,0.00007805117,0.0007571713],"genre_scores_gemma":[0.98837703,0.000029683091,0.00008902833,0.009707142,0.000040776387,0.000021667965,0.00002043208,0.000007996888,0.0017062596],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984128,0.00017909743,0.00020630393,0.00034356842,0.0006288635,0.00022939172],"domain_scores_gemma":[0.9986794,0.000103919636,0.00015454268,0.00035562576,0.00014785829,0.0005586591],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005555694,0.00012146924,0.0002273217,0.000042652136,0.00034068446,0.000027923192,0.00023023841,0.00005454142,0.00093896844],"category_scores_gemma":[0.0007795612,0.00006926292,0.000084621504,0.00083488435,0.00081561384,0.00015445352,0.00003859037,0.00012607481,0.00001000419],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005272021,0.015854169,0.7781657,0.0014701597,0.0044964384,0.0070310733,0.047223136,0.0014538796,0.05556492,0.03355326,0.03967245,0.0102428],"study_design_scores_gemma":[0.006492133,0.0016944886,0.9113686,0.00045392162,0.0007500425,0.000055677425,0.0049896,0.00766611,0.045667443,0.012630289,0.0075042304,0.0007274427],"about_ca_topic_score_codex":0.000056644723,"about_ca_topic_score_gemma":0.000022094582,"teacher_disagreement_score":0.13320293,"about_ca_system_score_codex":0.000033358014,"about_ca_system_score_gemma":0.0027166097,"threshold_uncertainty_score":0.9999743},"labels":[],"label_agreement":null},{"id":"W3163892036","doi":"10.1016/j.cellsig.2021.110040","title":"p62/Sequestosome 1 regulates transforming growth factor beta signaling and epithelial to mesenchymal transition in A549 cells","year":2021,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Sequestosome 1; A549 cell; Cell biology; Epithelial–mesenchymal transition; Gene silencing; Smad2 Protein; Small interfering RNA; Transforming growth factor; Signal transduction; Autophagy; Biology; Transforming growth factor beta; Chemistry; Cancer research; Cell; Cell culture; Downregulation and upregulation; Apoptosis; Transfection; Biochemistry","score_opus":0.014483080178488629,"score_gpt":0.2378514324613492,"score_spread":0.2233683522828606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3163892036","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97301936,0.00241071,0.023281312,0.0005627486,0.0001258273,0.00039622077,0.00002921812,0.000067924506,0.00010668009],"genre_scores_gemma":[0.99674046,0.00022165915,0.0019758386,0.00049464934,0.0002882048,0.000017173714,0.00006701683,0.00005161516,0.00014337299],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99825376,0.00008989297,0.00043103908,0.00049067044,0.0003137786,0.00042083766],"domain_scores_gemma":[0.9992766,0.00009430752,0.000049714403,0.00017365877,0.00010367978,0.00030206775],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022953373,0.00026145636,0.00044985264,0.00019814676,0.00011318905,0.000050715906,0.00007826518,0.00016397827,0.00029616256],"category_scores_gemma":[0.000015909936,0.00026322927,0.00016024556,0.0003303003,0.000048060876,0.00017000618,0.00001575154,0.00027063076,0.000020048277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016163442,0.00011733483,0.00020666295,0.00018732362,0.00006830799,0.00085011596,0.0034068483,0.0003667056,0.9926542,0.00024035244,0.000002105433,0.001738417],"study_design_scores_gemma":[0.0014392993,0.0001556505,0.00038380196,0.0004721426,0.00010413237,0.00003156986,0.00036218207,0.0013172769,0.9945117,0.00075346616,0.00018247316,0.0002862612],"about_ca_topic_score_codex":0.000030780946,"about_ca_topic_score_gemma":0.000005799061,"teacher_disagreement_score":0.02372111,"about_ca_system_score_codex":0.00006522258,"about_ca_system_score_gemma":0.00013257576,"threshold_uncertainty_score":0.999982},"labels":[],"label_agreement":null},{"id":"W3164416061","doi":"10.1139/bcb-2020-0283","title":"Synergistic effects of autophagy inhibitors combined with cisplatin against cisplatin-resistant nasopharyngeal cancer cells","year":2021,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autophagy; Cisplatin; Propidium iodide; Annexin; Apoptosis; Cancer research; ABCC1; Cancer cell; In vivo; Chemistry; Viability assay; Programmed cell death; Cell culture; MTT assay; Biology; Cancer; Biochemistry; Chemotherapy; ATP-binding cassette transporter","score_opus":0.004667194196193033,"score_gpt":0.2311961251097752,"score_spread":0.22652893091358217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3164416061","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9872912,0.010047743,0.000015004836,0.000060933424,0.00017482262,0.00017089961,0.000054448858,0.000031823332,0.0021530837],"genre_scores_gemma":[0.9972176,0.0006789916,0.00014113217,0.0002984568,0.00015022482,0.000032542186,0.00017452019,0.000020136422,0.001286381],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989281,0.00004570439,0.00027034013,0.0003949832,0.00010405905,0.0002568116],"domain_scores_gemma":[0.99914044,0.00015205957,0.00014813722,0.00027811548,0.00009758325,0.00018363813],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000489302,0.0002292635,0.00044801558,0.000028032113,0.00006342603,0.0000067027113,0.00006475402,0.00022504402,0.000121998695],"category_scores_gemma":[0.000027555885,0.00018039632,0.000071348506,0.00014425727,0.00024289239,0.000014679163,0.000044967717,0.00015415897,0.0000028309394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009490223,0.0003230906,0.00077189534,0.0011885584,0.00015357332,0.00038892496,0.000043703585,0.0000028210818,0.994465,0.00005851777,0.00021002357,0.0014448814],"study_design_scores_gemma":[0.0037380345,0.00060058973,0.0013173023,0.00025419256,0.00018686245,0.0000064098012,0.00004069614,0.00004871929,0.9931569,0.00003658801,0.00042759706,0.00018612204],"about_ca_topic_score_codex":0.000014379731,"about_ca_topic_score_gemma":0.0000015819057,"teacher_disagreement_score":0.009926374,"about_ca_system_score_codex":0.00002940524,"about_ca_system_score_gemma":0.00027770604,"threshold_uncertainty_score":0.73563486},"labels":[],"label_agreement":null},{"id":"W3164752133","doi":"10.1080/15548627.2021.1936932","title":"Silencing PEX26 as an unconventional mode to kill drug-resistant cancer cells and forestall drug resistance","year":2021,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke; Montreal Children's Hospital; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Cancer Society; Cancer Research Society; Canadian Institutes of Health Research; Réseau de cancérologie Rossy; Israel Cancer Research Fund","keywords":"Biology; Autophagy; Cancer research; Autophagosome; Cancer cell; ATG5; Gene silencing; Cell biology; Cancer; Apoptosis; Biochemistry","score_opus":0.00934465492255059,"score_gpt":0.3001645104642921,"score_spread":0.2908198555417415,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3164752133","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98910785,0.005750116,0.00010419266,0.0016551708,0.0003342982,0.00031153424,0.00009529535,0.000105917876,0.002535618],"genre_scores_gemma":[0.95714515,0.000396587,0.0012887766,0.0033821028,0.000268717,0.000078508485,0.000065458065,0.000049427148,0.037325248],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981766,0.000077878336,0.0003219627,0.0005953945,0.00043024519,0.0003979734],"domain_scores_gemma":[0.99868476,0.00007301492,0.00008222991,0.00047942772,0.00019855076,0.0004820029],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014669368,0.00024088628,0.0003565654,0.00008802426,0.000168225,0.000051992727,0.00012030446,0.000070916816,0.0011558178],"category_scores_gemma":[0.000039255185,0.00023334632,0.0001221049,0.00023733113,0.00007210192,0.00016749553,0.00007115584,0.00016705989,0.00006625551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002529767,0.0013001942,0.0017528746,0.0008823847,0.00067737227,0.004278858,0.0084402645,0.0004048457,0.91253406,0.03167422,0.028106026,0.007419147],"study_design_scores_gemma":[0.004006322,0.00017522146,0.039268862,0.0007681023,0.00030471035,0.00005300222,0.0012044895,0.0009145344,0.8919855,0.015457034,0.04512742,0.00073480373],"about_ca_topic_score_codex":0.00049052376,"about_ca_topic_score_gemma":0.0014490832,"teacher_disagreement_score":0.03751599,"about_ca_system_score_codex":0.00014412013,"about_ca_system_score_gemma":0.0005825402,"threshold_uncertainty_score":0.9997573},"labels":[],"label_agreement":null},{"id":"W3165430529","doi":"10.7554/elife.62320","title":"Multiplexed proteomics of autophagy-deficient murine macrophages reveals enhanced antimicrobial immunity via the oxidative stress response","year":2021,"lang":"en","type":"article","venue":"eLife","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"H2020 European Research Council; Genentech; AXA Research Fund","keywords":"Autophagy; Proteomics; Oxidative stress; Cell biology; Immunity; Antimicrobial; Biology; Immune system; Microbiology; Chemistry; Immunology; Biochemistry; Apoptosis","score_opus":0.012823222280251479,"score_gpt":0.2833408198156157,"score_spread":0.27051759753536425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3165430529","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99630284,0.00094628736,0.000698671,0.0006702925,0.00019151239,0.0008107046,0.00016242063,0.00006581265,0.00015148193],"genre_scores_gemma":[0.99448127,0.00020124367,0.002694448,0.0009524331,0.00012361883,0.000049360682,0.00007876543,0.00003418719,0.001384704],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980185,0.0005128253,0.00047282287,0.00030884572,0.00038156612,0.00030545765],"domain_scores_gemma":[0.99807274,0.00028273536,0.00024500917,0.0008411956,0.00043961802,0.00011868758],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056542986,0.00022315451,0.0004539027,0.000069209374,0.00017936167,0.000019468263,0.00021946049,0.000105438274,0.0003491021],"category_scores_gemma":[0.0005952854,0.00016247123,0.000204118,0.00034607406,0.00022825143,0.000057647485,0.0001505201,0.0003110304,0.00003936345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034333398,0.00077001774,0.00032122034,0.000099029465,0.0001941871,0.00012522943,0.0014410281,0.000039450544,0.9926333,0.00004038356,0.0002802781,0.00062257523],"study_design_scores_gemma":[0.0023894673,0.00020101966,0.06354654,0.00019146976,0.00008213598,0.000029912868,0.00032669332,0.00008815012,0.9327768,0.000032858967,0.00019496893,0.00013995943],"about_ca_topic_score_codex":0.000037620495,"about_ca_topic_score_gemma":0.0000046245596,"teacher_disagreement_score":0.06322532,"about_ca_system_score_codex":0.000066447465,"about_ca_system_score_gemma":0.00032749283,"threshold_uncertainty_score":0.66253847},"labels":[],"label_agreement":null},{"id":"W3166413205","doi":"10.3390/ijms22115992","title":"Autophagy, Unfolded Protein Response, and Neuropilin-1 Cross-Talk in SARS-CoV-2 Infection: What Can Be Learned from Other Coronaviruses","year":2021,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autophagy; PI3K/AKT/mTOR pathway; Biology; Cytokine storm; Coronavirus; Immune system; Immunology; Cellular stress response; Innate immune system; Cell biology; Unfolded protein response; Virology; Signal transduction; Apoptosis; Medicine; Coronavirus disease 2019 (COVID-19); Genetics","score_opus":0.11189262622613028,"score_gpt":0.4339144848557921,"score_spread":0.3220218586296618,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3166413205","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.43214217,0.56668824,0.00002041981,0.00042863336,0.00049189606,0.00017390786,0.000017936203,0.0000071159075,0.000029675695],"genre_scores_gemma":[0.0251365,0.972545,0.00029783603,0.0016251161,0.00024346991,0.000015651643,0.000012804036,0.000032740096,0.000090827765],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99714196,0.00047482195,0.0007929125,0.00038702722,0.0010149458,0.00018830707],"domain_scores_gemma":[0.99850637,0.00019324469,0.000685737,0.00018412295,0.00033255963,0.00009795887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007307595,0.00027805907,0.00086672266,0.0005196431,0.00006108563,0.0005019241,0.00045977312,0.00016351315,0.00011003679],"category_scores_gemma":[0.00039246716,0.0002152346,0.00039975697,0.0003624454,0.0003941868,0.0004013955,0.000107912616,0.00045702685,0.0000037281086],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009157578,0.0005886341,0.0006555765,0.00048316648,0.0012691083,0.017035406,0.00046137423,0.000028984758,0.019747704,0.000334787,0.000055255652,0.95842427],"study_design_scores_gemma":[0.003915188,0.0011865686,0.0035589954,0.041140042,0.00061089586,0.0041177156,0.00015817114,0.000044007604,0.045661144,0.001431999,0.8974218,0.00075348775],"about_ca_topic_score_codex":0.00021801148,"about_ca_topic_score_gemma":0.000033456618,"teacher_disagreement_score":0.95767075,"about_ca_system_score_codex":0.0001504238,"about_ca_system_score_gemma":0.0014770385,"threshold_uncertainty_score":0.8777012},"labels":[],"label_agreement":null},{"id":"W3166506374","doi":"10.2139/ssrn.3596603","title":"Protective Role of Mitophagy Associated Metabolic Reprogramming of Peripheral Macrophages During Tuberculosis","year":2020,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Mitophagy; Tuberculosis; Reprogramming; Peripheral; Medicine; Biology; Immunology; Genetics; Autophagy; Pathology; Cell; Internal medicine","score_opus":0.005758810515382784,"score_gpt":0.23895091728140036,"score_spread":0.23319210676601757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3166506374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97095746,0.02790692,0.0002053136,0.00041114204,0.000032090225,0.00033578448,0.0000060008347,0.000040560783,0.00010472966],"genre_scores_gemma":[0.9973685,0.0020907552,0.00008662826,0.00006690624,0.00023529974,0.000015314798,0.0000037700797,0.00003886939,0.00009391761],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99771243,0.00011993106,0.00047138604,0.00023146087,0.00037929212,0.0010854764],"domain_scores_gemma":[0.9990643,0.000016900825,0.00038190043,0.00016410598,0.00020806653,0.00016472257],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042715413,0.00018457633,0.0005570905,0.00009052563,0.00010981613,0.000011076871,0.00015302673,0.00010161945,0.00009084283],"category_scores_gemma":[0.00019012256,0.00015964589,0.00036518608,0.00038659194,0.00007393898,0.00010767755,0.00003253225,0.0011037046,0.0000029395912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026195522,0.00087334454,0.030926954,0.0001676759,0.0061539668,0.00006894379,0.0039687143,0.0000628421,0.90006363,0.004233424,0.000006703935,0.050854232],"study_design_scores_gemma":[0.007394461,0.002943485,0.10663543,0.00019802828,0.00089804904,0.0004776504,0.0072351983,0.0003092882,0.8515602,0.021827232,0.00014363638,0.0003773711],"about_ca_topic_score_codex":0.00007866281,"about_ca_topic_score_gemma":0.000018337809,"teacher_disagreement_score":0.07570847,"about_ca_system_score_codex":0.0002619307,"about_ca_system_score_gemma":0.0008954752,"threshold_uncertainty_score":0.651017},"labels":[],"label_agreement":null},{"id":"W3167351821","doi":"10.1096/fasebj.2021.35.s1.03058","title":"MicroRNA miR‐378‐3p is an Essential Regulator of Autophagy and Proliferation in Endothelial Cells","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Autophagy; Cell biology; Gene silencing; microRNA; Downregulation and upregulation; Lysosome; PI3K/AKT/mTOR pathway; Biology; Regulator; Chemistry; Signal transduction; Biochemistry; Apoptosis; Gene","score_opus":0.012439005062645055,"score_gpt":0.26658393748168413,"score_spread":0.25414493241903907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3167351821","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997613,0.0010975878,0.00009376339,0.0007003652,0.00020535721,0.00014141794,0.00002437824,0.000008343654,0.00011574563],"genre_scores_gemma":[0.99763393,0.00029058484,0.0003170321,0.0006937878,0.0005023649,0.000002497879,0.000007292099,0.000015016776,0.00053746544],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903995,0.00013328744,0.00030042388,0.00013477083,0.00022660964,0.00016496962],"domain_scores_gemma":[0.99940574,0.000026050193,0.00012862841,0.0002084943,0.000100469835,0.00013064254],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002638373,0.00010399623,0.00021717604,0.00006705959,0.00009064311,0.00003690873,0.00007657697,0.00006276378,0.0005265489],"category_scores_gemma":[0.000017720846,0.00007290466,0.0000807381,0.00010536179,0.00008409721,0.00010954648,0.000020860602,0.00023178245,0.000006368701],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039090533,0.00021165039,0.0014671403,0.00002545058,0.00006918011,0.0002265267,0.0015764948,0.0000068673116,0.9942123,0.000121135185,0.00021721006,0.001475106],"study_design_scores_gemma":[0.0024604385,0.00015533251,0.013368296,0.00007287546,0.000079712045,0.00075716025,0.00026146125,0.00039465184,0.98149717,0.00068245054,0.00020210828,0.000068373636],"about_ca_topic_score_codex":0.000009497107,"about_ca_topic_score_gemma":0.000005722475,"teacher_disagreement_score":0.012715193,"about_ca_system_score_codex":0.000027677323,"about_ca_system_score_gemma":0.00027679,"threshold_uncertainty_score":0.5765341},"labels":[],"label_agreement":null},{"id":"W3167975605","doi":"10.1016/j.archoralbio.2021.105200","title":"Effects of tetrahydrocannabinols on human oral cancer cell proliferation, apoptosis, autophagy, oxidative stress, and DNA damage","year":2021,"lang":"en","type":"review","venue":"Archives of Oral Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Viability assay; Oxidative stress; Apoptosis; Cancer cell; Cell growth; Cancer; Chemistry; Reactive oxygen species; Cell cycle checkpoint; Cell cycle; PI3K/AKT/mTOR pathway; Cancer research; Pharmacology; Cell biology; Biology; Biochemistry","score_opus":0.03084067583970099,"score_gpt":0.3689429304119068,"score_spread":0.3381022545722058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3167975605","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.058612783,0.9391702,0.000009597022,0.000031045536,0.00009847946,0.0011792687,0.00032258691,0.000022133216,0.00055392674],"genre_scores_gemma":[0.04018226,0.95800185,0.00019642278,0.00009291475,0.00009061973,0.00018446408,0.00092553376,0.000039723556,0.0002862101],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99816036,0.00042678035,0.00055668823,0.00048450293,0.00010561629,0.00026602758],"domain_scores_gemma":[0.9987332,0.00028705125,0.00045880632,0.00034656777,0.000046118337,0.00012824827],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00005912958,0.00039971518,0.0020481232,0.00017233811,0.000058104877,0.0000061993014,0.00018272502,0.0002383402,0.0000910801],"category_scores_gemma":[0.000050251307,0.00029093414,0.0003378999,0.00013236474,0.0005041169,0.000035966135,0.000102001075,0.0002852093,0.0000018232022],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023723331,0.0018926058,0.00067505543,0.064083174,0.0025799356,0.00005717766,0.0007411753,7.0802247e-7,0.031375684,0.004795058,0.00051504676,0.89304715],"study_design_scores_gemma":[0.005110069,0.006261912,0.003950178,0.040047072,0.004818231,0.00001438163,0.0000784814,0.000009515398,0.7440457,0.0014885063,0.19310553,0.0010704428],"about_ca_topic_score_codex":0.00016217987,"about_ca_topic_score_gemma":0.000022980556,"teacher_disagreement_score":0.8919767,"about_ca_system_score_codex":0.00002486923,"about_ca_system_score_gemma":0.0003447496,"threshold_uncertainty_score":0.9999543},"labels":[],"label_agreement":null},{"id":"W3170119068","doi":"10.3389/fphys.2021.703458","title":"Editorial: Autophagy and Mitophagy in Skeletal Muscle Health and Disease","year":2021,"lang":"en","type":"editorial","venue":"Frontiers in Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal; Institut Universitaire de Gériatrie de Montréal; Christie (Canada); McGill University Health Centre; McGill University","funders":"Fonds de Recherche du Québec - Santé","keywords":"Mitophagy; Autophagy; Skeletal muscle; Medicine; Muscle disease; Disease; Biology; Internal medicine; Genetics","score_opus":0.005183155486318144,"score_gpt":0.2711377056051925,"score_spread":0.26595455011887437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3170119068","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.021001521,0.06287135,0.000013390352,0.00027982364,0.9151292,0.00048888667,0.00013946393,0.000044026787,0.00003233763],"genre_scores_gemma":[0.003168584,0.013865647,0.00042651343,0.00073804427,0.9801628,0.00011075616,0.0011765665,0.000080940496,0.00027016952],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99712855,0.00032389484,0.0005518152,0.0009892088,0.0003895226,0.0006170167],"domain_scores_gemma":[0.9983507,0.00021734524,0.00020019615,0.0004878192,0.00008326652,0.0006606974],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002327906,0.00045041877,0.0014471619,0.00035475442,0.0000646114,0.000021840719,0.00014615347,0.00087006605,0.000026571053],"category_scores_gemma":[0.00073134655,0.00044916128,0.00013072311,0.00023672619,0.00032632993,0.000085520616,0.00015125073,0.0011683805,0.0000027385704],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004676206,0.00028053607,0.0005271857,0.00071473984,0.000098143,0.00020249432,0.00024916473,0.0000011821819,0.00015040782,0.000018681547,0.9918164,0.0054734163],"study_design_scores_gemma":[0.004411312,0.0004008738,0.014690867,0.0004453119,0.000052274874,0.0000017579857,0.00016814997,0.00008428197,0.000011149762,0.0035093005,0.97585285,0.00037189783],"about_ca_topic_score_codex":0.0001557482,"about_ca_topic_score_gemma":0.000017550541,"teacher_disagreement_score":0.06503358,"about_ca_system_score_codex":0.00024489348,"about_ca_system_score_gemma":0.0020993038,"threshold_uncertainty_score":0.99979603},"labels":[],"label_agreement":null},{"id":"W3170205587","doi":"10.3389/fmicb.2021.647410","title":"Autophagy Receptor Protein Tax1-Binding Protein 1/TRAF6-Binding Protein Is a Cellular Substrate of Enteroviral Proteinase","year":2021,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Optineurin; Cell biology; Mitophagy; Biology; Ubiquitin; Viral replication; Signal transducing adaptor protein; ATG16L1; Protein degradation; Biochemistry; Signal transduction; Virology; Virus; Apoptosis","score_opus":0.009759763803223647,"score_gpt":0.23292717766921545,"score_spread":0.2231674138659918,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3170205587","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.991166,0.001996002,0.0007466468,0.0006136533,0.00046672244,0.0044550854,0.00022553813,0.00010412512,0.00022622423],"genre_scores_gemma":[0.9634156,0.000031668733,0.021663701,0.0002053219,0.00014951712,0.00089859916,0.0005211287,0.00010537133,0.013009089],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963989,0.00039837614,0.0010344471,0.0009995686,0.00019716227,0.0009715498],"domain_scores_gemma":[0.99835396,0.000016966114,0.00047678023,0.00074475235,0.00018517984,0.0002223708],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050246116,0.00053840043,0.0011593883,0.00047084416,0.00012709896,0.000031512096,0.0003579422,0.00058144034,0.00088889565],"category_scores_gemma":[0.00013922367,0.00053060474,0.00036397838,0.00066897745,0.00040600114,0.00016598916,0.00013732242,0.0007508966,0.000095329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009978911,0.0006815622,0.00399449,0.00063684274,0.0003085708,0.0007118058,0.0005046156,7.27945e-7,0.98964334,0.00013269468,0.0014691872,0.00091829407],"study_design_scores_gemma":[0.0041399896,0.00069968466,0.00013025667,0.0011419915,0.000062868276,0.00005806701,0.00056414603,0.000025294537,0.9880137,0.00027701963,0.0044406145,0.0004463546],"about_ca_topic_score_codex":0.000034842935,"about_ca_topic_score_gemma":0.000006567714,"teacher_disagreement_score":0.027750399,"about_ca_system_score_codex":0.0003271328,"about_ca_system_score_gemma":0.0006287142,"threshold_uncertainty_score":0.99971455},"labels":[],"label_agreement":null},{"id":"W3170672239","doi":"10.1096/fasebj.2021.35.s1.04166","title":"Autophagy in Peripheral Blood Mononuclear Cells of Older Adults Following Day‐Long Exposure to Increasing Levels of Ambient Heat Stress: Preliminary Observations","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Peripheral blood mononuclear cell; Oxidative stress; Medicine; Heat stress; Stressor; Ageing; Ex vivo; Physiology; In vivo; Internal medicine; Chemistry; Biology; Animal science; In vitro; Biochemistry; Apoptosis; Genetics","score_opus":0.017901562727889727,"score_gpt":0.25831387016112545,"score_spread":0.24041230743323572,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3170672239","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965045,0.002315718,0.00021292694,0.00036703548,0.0002001608,0.0002782646,0.000038192855,0.00001290119,0.00007033515],"genre_scores_gemma":[0.99807745,0.0000900891,0.001151166,0.00034922292,0.0001389062,0.0000061777755,0.000008294633,0.000029072417,0.00014959232],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998302,0.0002796663,0.00057027023,0.00017824234,0.0004039504,0.00026590138],"domain_scores_gemma":[0.9990283,0.00013679988,0.00013781482,0.00034964512,0.00016819,0.0001792131],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004784539,0.00015796219,0.00038457423,0.000110277455,0.000123518,0.000023489252,0.00017681699,0.00007328256,0.00028487807],"category_scores_gemma":[0.000109029075,0.00012225876,0.0002542868,0.00033527907,0.0000429491,0.00013753996,0.00007397674,0.000317329,0.0000019496767],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00083332503,0.0010854765,0.04527799,0.00012264177,0.0003930002,0.0011396937,0.011760831,0.0025142953,0.9349457,0.000021311553,0.00004221534,0.0018635298],"study_design_scores_gemma":[0.0023580533,0.00039873295,0.49838933,0.0013917724,0.00017898157,0.00015915236,0.0022329798,0.0002983386,0.49448216,0.000026900536,0.0000027999909,0.000080784885],"about_ca_topic_score_codex":0.00007713871,"about_ca_topic_score_gemma":0.000014105217,"teacher_disagreement_score":0.45311135,"about_ca_system_score_codex":0.00005738417,"about_ca_system_score_gemma":0.00026227118,"threshold_uncertainty_score":0.49855676},"labels":[],"label_agreement":null},{"id":"W3172011433","doi":"10.22215/etd/2020-14320","title":"Frozen but alive: Molecular responses to autophagy, angiogenesis and energy metabolism in the stress-tolerant wood frog, Rana sylvatica","year":2020,"lang":"en","type":"dissertation","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Torpor; Angiogenesis; Dehydration; Internal medicine; Cell biology; Endocrinology; Biochemistry; Chemistry; Medicine; Thermoregulation; Genetics","score_opus":0.010583020232921386,"score_gpt":0.27797512297550286,"score_spread":0.26739210274258146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3172011433","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9685583,0.02436051,0.00013587977,0.0018736096,0.00019915699,0.00062687433,0.00016317765,0.00009385835,0.0039885957],"genre_scores_gemma":[0.9811524,0.0013102504,0.00059676403,0.009428667,0.00023458328,0.00030744652,0.0012100386,0.0001041602,0.005655647],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9975638,0.00030296392,0.0005153707,0.00064098905,0.00061141973,0.00036549725],"domain_scores_gemma":[0.9986888,0.0001989501,0.00012845382,0.00057748583,0.00010814861,0.0002981275],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018316631,0.0004890597,0.0008631917,0.00035407458,0.00009187409,0.00007068929,0.0003194492,0.00031397876,0.0004545158],"category_scores_gemma":[0.00014253936,0.00034299982,0.00028309633,0.00047921666,0.00004057444,0.000054920103,0.000035947847,0.00023171656,0.000026017919],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.062490184,0.0052946354,0.0030937938,0.0036721958,0.015750133,0.025912547,0.08318284,0.00009435591,0.52823704,0.09450091,0.020234585,0.15753677],"study_design_scores_gemma":[0.011217503,0.001074489,0.46859688,0.0013916561,0.0052948133,0.00009087985,0.020192977,0.0007587975,0.44806993,0.002687672,0.03836061,0.0022637933],"about_ca_topic_score_codex":0.000947185,"about_ca_topic_score_gemma":0.00018964696,"teacher_disagreement_score":0.4655031,"about_ca_system_score_codex":0.000028936647,"about_ca_system_score_gemma":0.00027431658,"threshold_uncertainty_score":0.9999022},"labels":[],"label_agreement":null},{"id":"W3173295290","doi":"10.1096/fasebj.2019.33.1_supplement.701.5","title":"Nix induced mitochondrial fission, mitophagy, and myocyte insulin resistance are abrogated by PKA phosphorylation","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Research Manitoba","keywords":"Mitophagy; Lipotoxicity; Insulin resistance; Autophagy; Endocrinology; Biology; Internal medicine; Cell biology; MFN2; Mitochondrial fission; Mitochondrion; Insulin; mitochondrial fusion; Biochemistry; Mitochondrial DNA; Apoptosis; Gene","score_opus":0.009558644270201947,"score_gpt":0.24759007600122387,"score_spread":0.23803143173102193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3173295290","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904455,0.0063827583,0.00004201822,0.0015641808,0.00064834807,0.00035071105,0.000018205872,0.0000366985,0.0005116024],"genre_scores_gemma":[0.9935558,0.0006727712,0.0001098972,0.00089809444,0.0005434876,0.0000052247433,0.000019465053,0.000026629321,0.0041686464],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987621,0.00011420757,0.0003118553,0.00019782405,0.000370186,0.00024384385],"domain_scores_gemma":[0.9990012,0.00007734019,0.00027120506,0.00029203782,0.00012270131,0.00023549459],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020757873,0.00017327776,0.00026222275,0.000061534694,0.0002479439,0.00006411993,0.00014081816,0.0001235397,0.00057670916],"category_scores_gemma":[0.00007336902,0.00011167148,0.000093654045,0.00016778357,0.00005807629,0.00014039586,0.00002694337,0.0005027562,0.000091962516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0031315102,0.00014241361,0.005550664,0.000032544678,0.00018680458,0.00009217665,0.0006777354,0.000004033911,0.96428704,0.000035743025,0.023017824,0.002841479],"study_design_scores_gemma":[0.011661953,0.00042970217,0.076143414,0.000584012,0.00018243324,0.0002836604,0.0007465182,0.00020944914,0.89627093,0.0011099265,0.012040564,0.00033742245],"about_ca_topic_score_codex":0.000009029158,"about_ca_topic_score_gemma":0.0000025242698,"teacher_disagreement_score":0.070592746,"about_ca_system_score_codex":0.000070337315,"about_ca_system_score_gemma":0.00011663158,"threshold_uncertainty_score":0.63145614},"labels":[],"label_agreement":null},{"id":"W3173824481","doi":"10.1096/fasebj.26.1_supplement.691.11","title":"Determining how 4‐phenylbutyrate inhibits tunicamycininduced acute kidney injury","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Tunicamycin; Phenylbutyrate; Acute kidney injury; Unfolded protein response; Nephrotoxicity; Pharmacology; Chemistry; Histone deacetylase inhibitor; Endoplasmic reticulum; Kidney; Vacuolization; Medicine; Internal medicine; Histone deacetylase; Endocrinology; Biochemistry; Histone","score_opus":0.027552557436392067,"score_gpt":0.2974196888216554,"score_spread":0.26986713138526336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3173824481","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99261487,0.00055137736,0.00013346843,0.0040694084,0.00070441846,0.00015883108,0.00002429859,0.000056955356,0.0016863953],"genre_scores_gemma":[0.9897499,0.00041334634,0.000285015,0.0059127985,0.0017935688,0.0000072155067,0.000010547922,0.00004041156,0.0017871732],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99856323,0.0001431597,0.0002517361,0.00012219918,0.000363834,0.0005558362],"domain_scores_gemma":[0.99838895,0.0000450564,0.00021067554,0.00038369792,0.0000850125,0.00088660565],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00063297234,0.00020365261,0.00027984238,0.00009718275,0.00035849249,0.000082062674,0.00022510544,0.000093218616,0.0004397909],"category_scores_gemma":[0.00011751794,0.00012247758,0.00020009372,0.00016504695,0.00009573565,0.00035654657,0.0000656463,0.00065578433,0.00013636444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004876286,0.00020172219,0.015502868,0.000018326384,0.00068828097,0.00020343662,0.0016951812,2.704102e-7,0.9512996,0.00012666233,0.013822914,0.015953088],"study_design_scores_gemma":[0.0029407244,0.00048094228,0.02124526,0.00026035085,0.00077559875,0.0040953676,0.0003959435,0.00008631376,0.9592063,0.0003033005,0.00989063,0.0003193026],"about_ca_topic_score_codex":8.995492e-7,"about_ca_topic_score_gemma":5.6158232e-8,"teacher_disagreement_score":0.015633786,"about_ca_system_score_codex":0.00006481102,"about_ca_system_score_gemma":0.00025456146,"threshold_uncertainty_score":0.49944904},"labels":[],"label_agreement":null},{"id":"W3173932728","doi":"10.1096/fasebj.2019.33.1_supplement.lb649","title":"Protective roles of autophagy in sepsis‐induced skeletal muscle dysfunction, metabolic derangements and mortality","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University; Christie (Canada); Université du Québec à Montréal","funders":"Canadian Institutes of Health Research","keywords":"Sepsis; Autophagy; Skeletal muscle; Endocrinology; Medicine; Internal medicine; Biology; Apoptosis; Biochemistry","score_opus":0.018058278405651475,"score_gpt":0.28417772753939724,"score_spread":0.26611944913374574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3173932728","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972127,0.0015475532,0.000067548506,0.00015172304,0.00015510201,0.00048321622,0.0000049548057,0.000011793335,0.00036542708],"genre_scores_gemma":[0.9993647,0.00014377538,0.000026094134,0.00022220632,0.000121795056,0.0000129088985,0.0000019170186,0.000012746091,0.00009387252],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99901354,0.00013453483,0.00026812253,0.00013112454,0.0002750586,0.00017759332],"domain_scores_gemma":[0.9994354,0.000035662455,0.00015582956,0.00020480958,0.000077884324,0.00009040847],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046587992,0.00011608028,0.00027631185,0.000102343045,0.00007354004,0.000015576066,0.00008277755,0.0000507332,0.00034702462],"category_scores_gemma":[0.00003665576,0.00007395712,0.000096313444,0.00014819134,0.00005309018,0.00011845658,0.000026980333,0.00029220522,0.000015264419],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004728205,0.00055342354,0.11764599,0.000108486034,0.00097094267,0.00010898398,0.0025228611,0.00004754317,0.8468316,0.00043568926,0.0000430323,0.030258635],"study_design_scores_gemma":[0.002784521,0.00021262019,0.90651065,0.00007670382,0.00013835101,0.0000654906,0.00047572603,0.00016507787,0.08791774,0.0015139201,0.0000670176,0.000072182076],"about_ca_topic_score_codex":0.00005354553,"about_ca_topic_score_gemma":0.000024547124,"teacher_disagreement_score":0.7888647,"about_ca_system_score_codex":0.000029417795,"about_ca_system_score_gemma":0.00011334726,"threshold_uncertainty_score":0.37996763},"labels":[],"label_agreement":null},{"id":"W3173971852","doi":"10.3390/ijms22126544","title":"Epigenetic Regulation of Autophagy in Cardiovascular Pathobiology","year":2021,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Epigenetics; microRNA; Histone; Biology; Cell biology; Regulation of gene expression; Bioinformatics; Computational biology; Gene; Genetics","score_opus":0.0360441974530998,"score_gpt":0.36660831776737357,"score_spread":0.3305641203142738,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3173971852","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004033046,0.9940575,0.0008455286,0.000041551273,0.0006490574,0.00013281514,0.000005964384,0.0000023792666,0.00023218765],"genre_scores_gemma":[0.018417573,0.98035204,0.00097356044,0.00005288539,0.0001564528,0.0000037427133,0.000013566477,0.000010730556,0.000019425164],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99769926,0.000269009,0.0008661958,0.00020568805,0.00083791785,0.00012193348],"domain_scores_gemma":[0.99861366,0.00007755432,0.0006512657,0.00017908635,0.00041747457,0.000060947703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008889934,0.00015182211,0.001247524,0.000608295,0.000013595328,0.000017465194,0.000464776,0.00014102897,0.00009082498],"category_scores_gemma":[0.0001673792,0.00011267571,0.0012047206,0.0003635898,0.00018427755,0.000058717746,0.00005485493,0.00020173959,0.000002647908],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013968214,0.00014173414,0.000043589793,0.00044240462,0.001432648,0.00185947,0.000050367747,0.00025561528,0.00037261922,0.00065850135,0.000011826615,0.99471724],"study_design_scores_gemma":[0.0029021166,0.0012264511,0.0028197751,0.04697623,0.0035538853,0.009686935,0.00013497856,0.0001243505,0.008758828,0.0026534968,0.92052096,0.0006419939],"about_ca_topic_score_codex":0.0000074027034,"about_ca_topic_score_gemma":4.65179e-7,"teacher_disagreement_score":0.99407524,"about_ca_system_score_codex":0.00009576381,"about_ca_system_score_gemma":0.0011355235,"threshold_uncertainty_score":0.45947823},"labels":[],"label_agreement":null},{"id":"W3174485528","doi":"10.1161/res.119.suppl_1.250","title":"Abstract 250: Differential Role of Autophagy in Idiopathic versus Ischemic Heart Failure in Humans","year":2016,"lang":"en","type":"article","venue":"Circulation Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; St. Michael's Hospital","funders":"","keywords":"Autophagy; ATG5; Heart failure; PI3K/AKT/mTOR pathway; Medicine; Internal medicine; Pathogenesis; Apoptosis; Pathological; Ischemia; Cardiology; Endocrinology; Biology; Biochemistry","score_opus":0.051639097093990984,"score_gpt":0.37257545247945056,"score_spread":0.32093635538545956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174485528","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997404,0.0005782717,0.000015095547,0.00055727945,0.000050650997,0.00033236702,0.0000046467626,0.000019986863,0.0010377318],"genre_scores_gemma":[0.99971414,0.000031743453,0.000010553081,0.000011636802,0.0001066308,0.000035160458,0.000010872663,0.000017180682,0.000062081344],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99842775,0.00011074586,0.0003217543,0.0002553439,0.00056197034,0.00032243846],"domain_scores_gemma":[0.9992627,0.00015102413,0.00004227386,0.00031826895,0.00012795719,0.000097808785],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005438187,0.000091907496,0.00023445798,0.00043778497,0.00003582037,0.000009760157,0.00010321214,0.00014433706,0.00095837517],"category_scores_gemma":[0.00018816267,0.00007211672,0.000073612755,0.00035927864,0.00012298985,0.000111760986,0.00003198354,0.000299778,0.00009079031],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065863214,0.00027857805,0.17594482,0.00007864363,0.000020597021,0.000023482628,0.0002836679,0.000018018998,0.8186939,0.00070986355,0.00011363527,0.0031761872],"study_design_scores_gemma":[0.0043667583,0.00008462636,0.9384219,0.0003033638,0.0000045847037,0.0000013005941,0.00013165374,0.00019919382,0.05550597,0.0006775641,0.00023212968,0.000070936214],"about_ca_topic_score_codex":0.00014566387,"about_ca_topic_score_gemma":0.00009796229,"teacher_disagreement_score":0.7631879,"about_ca_system_score_codex":0.00015803412,"about_ca_system_score_gemma":0.00020687758,"threshold_uncertainty_score":0.9999549},"labels":[],"label_agreement":null},{"id":"W3174838481","doi":"10.1096/fasebj.25.1_supplement.1107.5","title":"Importance of fiber type and contractile activity to autophagic protein expression in cardiac and skeletal muscle","year":2011,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Autophagy; Fiber type; Skeletal muscle; Cell biology; Cardiac muscle; Protein expression; Chemistry; Internal medicine; Fiber; Endocrinology; Biology; Medicine; Biochemistry; Gene","score_opus":0.019889257700445348,"score_gpt":0.26798978032991877,"score_spread":0.2481005226294734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174838481","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978907,0.0010263593,0.000009921949,0.00010333547,0.00005121216,0.00026477952,0.0000042459546,0.000006090288,0.0006433663],"genre_scores_gemma":[0.99931335,0.00009011982,0.00021986126,0.0000783057,0.00006570429,0.0000057465263,4.0633407e-7,0.000008488717,0.00021802798],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9994674,0.000068432135,0.00013010677,0.00009129801,0.0001193282,0.00012347719],"domain_scores_gemma":[0.9995873,0.00002745418,0.00008766277,0.00013165986,0.000042928914,0.00012301872],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027373456,0.00007503878,0.00018755329,0.000041752483,0.000049468894,0.000006968182,0.000042912307,0.000033914588,0.00023566892],"category_scores_gemma":[0.000045161218,0.00004660864,0.000032799544,0.00007848488,0.000055217555,0.00008766239,0.000023625644,0.00019717247,0.000004165222],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00060061034,0.00013380572,0.013475659,0.00002393232,0.000041883402,0.000087854096,0.0011455885,5.036254e-7,0.96675867,0.000018667935,0.000090576126,0.01762227],"study_design_scores_gemma":[0.00067780336,0.0002132049,0.6456363,0.00010229134,0.000026461104,0.000048041136,0.000091106056,0.000012759684,0.35275787,0.00022160672,0.00016221359,0.000050327682],"about_ca_topic_score_codex":0.000019510895,"about_ca_topic_score_gemma":0.0000020582859,"teacher_disagreement_score":0.63216066,"about_ca_system_score_codex":0.000014669972,"about_ca_system_score_gemma":0.000056511373,"threshold_uncertainty_score":0.25804093},"labels":[],"label_agreement":null},{"id":"W3174930272","doi":"10.1096/fasebj.22.1_supplement.1238.12","title":"Decreased anti‐apoptotic ARC and XIAP as well as elevated pro‐apoptotic Smac and procaspase‐8 protein in soleus muscle of hypertensive rats","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"XIAP; Apoptosis; Skeletal muscle; Endocrinology; Internal medicine; Soleus muscle; Western blot; Inhibitor of apoptosis; Caspase; Caspase 12; Chemistry; Myocyte; Medicine; Biochemistry; Gene; Programmed cell death","score_opus":0.018406815525036885,"score_gpt":0.2517274842251252,"score_spread":0.2333206687000883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174930272","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960574,0.0017340007,0.000012727769,0.0006639271,0.00004470502,0.0010265895,0.000004226723,0.000025438438,0.0004309839],"genre_scores_gemma":[0.99793196,0.00059153745,0.00018243058,0.00068019814,0.00010056727,0.000021352147,0.0000062063045,0.000034671764,0.0004510621],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983624,0.00017909547,0.00044466442,0.00024684452,0.00038898853,0.00037800215],"domain_scores_gemma":[0.99884707,0.00009062742,0.00024042801,0.0002640006,0.0002056272,0.00035225882],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003516221,0.00024371559,0.00050304,0.00018473933,0.00022524044,0.000025276444,0.00012569725,0.00009916031,0.0002143204],"category_scores_gemma":[0.00024251317,0.00015939755,0.000088120956,0.00024975603,0.00036513366,0.000119958495,0.000041209027,0.00047865152,0.0000379595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011750006,0.0005001376,0.0054935287,0.00011958521,0.00018558654,0.0015659805,0.0010156182,0.00000903241,0.98786354,0.000054995235,0.00010251332,0.0019144741],"study_design_scores_gemma":[0.0064036017,0.0012863475,0.07688285,0.000682109,0.00022779134,0.0055749356,0.0006519617,0.00064649514,0.9055867,0.0017151586,0.00009251346,0.00024950263],"about_ca_topic_score_codex":0.000094797906,"about_ca_topic_score_gemma":0.0000037401815,"teacher_disagreement_score":0.08227681,"about_ca_system_score_codex":0.000042026877,"about_ca_system_score_gemma":0.0004616594,"threshold_uncertainty_score":0.6500043},"labels":[],"label_agreement":null},{"id":"W3175076704","doi":"10.1096/fasebj.27.1_supplement.1129.14","title":"Autophagy in phenoconversion of differentiated and undifferentiated fibroblasts","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autophagy; ATG5; Myofibroblast; Fibroblast; Fibronectin; Cell biology; Chemistry; Western blot; Cancer research; Molecular biology; Biology; Pathology; Apoptosis; Fibrosis; Medicine; Extracellular matrix; In vitro; Biochemistry","score_opus":0.00938737707469041,"score_gpt":0.2323470065149682,"score_spread":0.22295962944027778,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175076704","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99851865,0.00061234785,0.00007476981,0.0002971685,0.00008556777,0.0002101648,0.0000020429604,0.000013435701,0.00018583208],"genre_scores_gemma":[0.99923015,0.00021053279,0.000036132118,0.00013703505,0.0000481649,0.0000032836156,0.000005529814,0.000011056033,0.0003181302],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99923736,0.00008151813,0.00024931238,0.00008782743,0.00016897389,0.00017499102],"domain_scores_gemma":[0.9995101,0.000047308364,0.000119136224,0.00014049304,0.00005858748,0.00012435004],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00010304831,0.00010334359,0.00021336884,0.00011361194,0.000064597996,0.000021813887,0.000085461725,0.00005172892,0.0016795971],"category_scores_gemma":[0.000016499493,0.000060024417,0.00006577544,0.00012206568,0.00008967392,0.00008726441,0.00003224261,0.00023351474,0.0000279186],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040537876,0.00035294078,0.0482575,0.000076166514,0.00025133084,0.0000563701,0.0010731395,0.0000074523637,0.9410057,0.0001496865,0.00059186155,0.007772489],"study_design_scores_gemma":[0.0033916638,0.00023292674,0.79817945,0.00020574807,0.00007603745,0.00016304594,0.00024042805,0.0015566044,0.1938462,0.00201874,0.000012191658,0.00007695258],"about_ca_topic_score_codex":0.000047650232,"about_ca_topic_score_gemma":0.0000018714982,"teacher_disagreement_score":0.749922,"about_ca_system_score_codex":0.000024847297,"about_ca_system_score_gemma":0.000041076073,"threshold_uncertainty_score":0.999233},"labels":[],"label_agreement":null},{"id":"W3175264841","doi":"10.1096/fasebj.2019.33.1_supplement.537.8","title":"Importance of TFEB and TFE3 in Mediating Lysosomal and Mitochondrial Adaptations","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"TFEB; Cell biology; Mitophagy; Proteostasis; Autophagy; Lysosome; Mitochondrion; Biogenesis; Proteotoxicity; Biology; Cytosol; Cathepsin; Cathepsin D; Chemistry; Biochemistry; Protein aggregation","score_opus":0.012437792801898011,"score_gpt":0.261550282951043,"score_spread":0.24911249014914497,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175264841","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99705046,0.0017852457,0.000022687294,0.0004988658,0.0001322385,0.0001282637,0.000004094018,0.000003869186,0.00037425486],"genre_scores_gemma":[0.99885005,0.00030720967,0.00033322637,0.00018440891,0.00020803534,0.0000016359093,0.0000017579924,0.000006508564,0.00010716255],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9994518,0.000036476922,0.00020094083,0.0000683288,0.0001404362,0.00010200718],"domain_scores_gemma":[0.9995957,0.000095229014,0.00011434065,0.00009266765,0.000028855216,0.000073229574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016200815,0.000057269004,0.00014419592,0.000051493298,0.00004649499,0.000009526698,0.000041475887,0.000025698568,0.00009653412],"category_scores_gemma":[0.00005314309,0.000036770907,0.00003027528,0.00006709554,0.00005637042,0.0000673219,0.000013655648,0.0001800489,0.0000025062664],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046998129,0.000078058096,0.53325707,0.000035491696,0.00009936467,0.00007712883,0.0027876329,0.000026215735,0.45638353,0.0006910746,0.000066321496,0.0060281493],"study_design_scores_gemma":[0.00546348,0.000334543,0.9603386,0.00018179754,0.000099609875,0.00059948774,0.0017188003,0.0014852728,0.027287869,0.0023181157,0.000066640234,0.00010578292],"about_ca_topic_score_codex":0.000008405433,"about_ca_topic_score_gemma":0.000008004247,"teacher_disagreement_score":0.42909566,"about_ca_system_score_codex":0.000010848844,"about_ca_system_score_gemma":0.00007808937,"threshold_uncertainty_score":0.14994742},"labels":[],"label_agreement":null},{"id":"W3175408709","doi":"10.1096/fasebj.2018.32.1_supplement.654.11","title":"Regulation of Mitophagy by the Parkin Ubiquitin Ligase and PINK1 Ubiquitin Kinase","year":2018,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Parkin; Mitophagy; PINK1; Ubiquitin ligase; Ubiquitin; Cell biology; Phosphorylation; Mitochondrion; Kinase; Biology; Autophagy; Chemistry; Biochemistry; Parkinson's disease; Medicine; Disease; Internal medicine","score_opus":0.013006841428567924,"score_gpt":0.26734845136183305,"score_spread":0.2543416099332651,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175408709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914564,0.0032549389,0.00019893258,0.0036778247,0.00015103916,0.00019854121,0.000016089069,0.000016377704,0.0010298763],"genre_scores_gemma":[0.99617153,0.00028596728,0.0000741015,0.0014572527,0.0010303212,0.0000047749663,0.0000070352444,0.00001786879,0.0009511434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988945,0.00016211622,0.00030899688,0.00011867431,0.00030075986,0.00021496549],"domain_scores_gemma":[0.99905795,0.0001205365,0.00023034854,0.00030582058,0.00013720329,0.00014812304],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006598385,0.00012735031,0.00019060254,0.000047901944,0.00032273892,0.0000360673,0.00015739388,0.000058585836,0.00058149546],"category_scores_gemma":[0.0000746292,0.00006642001,0.00009539691,0.00012401484,0.00043766655,0.000072870316,0.000036433445,0.00025330746,0.000020861917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009898964,0.00018167097,0.0016634486,0.000030611303,0.00022180032,0.000050364117,0.0016136164,0.0000019027162,0.94407374,0.0009173605,0.023101754,0.02715382],"study_design_scores_gemma":[0.001717133,0.0005453462,0.021205448,0.00013963542,0.00017482469,0.0007269585,0.00041267925,0.00023338861,0.96702814,0.003154435,0.0045703677,0.000091671995],"about_ca_topic_score_codex":0.000016253,"about_ca_topic_score_gemma":0.0000027891358,"teacher_disagreement_score":0.027062148,"about_ca_system_score_codex":0.000024964083,"about_ca_system_score_gemma":0.00008500896,"threshold_uncertainty_score":0.63669676},"labels":[],"label_agreement":null},{"id":"W3175805669","doi":"10.1096/fasebj.26.1_supplement.lb59","title":"Excessive autophagy contributes to neuron death in cerebral ischemia","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Michigan Institute for Clinical and Health Research; Manitoba Health Research Council","keywords":"Autophagy; Programmed cell death; Ischemia; Immunocytochemistry; Cell biology; Western blot; BECN1; Neuron; Hypoxia (environmental); Staining; Viability assay; In vivo; Chemistry; Cell; Biology; Apoptosis; Pathology; Neuroscience; Medicine; Internal medicine; Biochemistry; Oxygen; Gene","score_opus":0.01999122949920912,"score_gpt":0.29290870450773404,"score_spread":0.2729174750085249,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175805669","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923369,0.0026690932,0.00027526676,0.002339595,0.00041426282,0.00020916558,0.000005106435,0.000023459472,0.001727103],"genre_scores_gemma":[0.99371403,0.000058528934,0.0000916597,0.0045482516,0.0007906717,0.000010150998,0.0000034504064,0.000019230054,0.0007640105],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9988965,0.00009054972,0.00024356022,0.000098097655,0.0002179218,0.00045339996],"domain_scores_gemma":[0.9992382,0.000079792495,0.00008587678,0.0002109901,0.000053193944,0.00033197255],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040234195,0.00013560588,0.00022676628,0.000107861735,0.00012838714,0.00003335329,0.00016688183,0.00005811806,0.00046577558],"category_scores_gemma":[0.000101344136,0.00008284417,0.000103198305,0.00017560493,0.000037192363,0.0001471889,0.000041000716,0.00044556643,0.00013839966],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019690387,0.00089502876,0.5076062,0.00003828255,0.00040766518,0.00071912556,0.0033863287,0.00006394444,0.45828706,0.0039871843,0.013017104,0.009623043],"study_design_scores_gemma":[0.0028941163,0.0001742099,0.6075973,0.00011579211,0.00010925412,0.0006509138,0.00023111686,0.00006964856,0.38343284,0.00087128935,0.0037193156,0.00013423567],"about_ca_topic_score_codex":0.000012510672,"about_ca_topic_score_gemma":0.0000013250918,"teacher_disagreement_score":0.0999911,"about_ca_system_score_codex":0.000099113,"about_ca_system_score_gemma":0.00011045642,"threshold_uncertainty_score":0.5099916},"labels":[],"label_agreement":null},{"id":"W3176530220","doi":"10.1096/fasebj.2018.32.1_supplement.lb419","title":"Autophagy‐Related Protein 16L1 (Atg16L1) Depletion Induces Insulin Resistance Through Decreased IRS Expression","year":2018,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Autophagy; ATG5; IRS1; PI3K/AKT/mTOR pathway; Cell biology; Insulin-like growth factor 1 receptor; Protein kinase B; Insulin receptor substrate; Insulin receptor; Biology; Insulin; Growth factor; Insulin-like growth factor; Chemistry; Phosphorylation; Signal transduction; Receptor; Insulin resistance; Endocrinology; Biochemistry; Apoptosis","score_opus":0.01876677110859827,"score_gpt":0.280453662308599,"score_spread":0.26168689120000077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176530220","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98912185,0.0029852604,0.0009126463,0.0015952139,0.00033903067,0.00053253653,0.000007572058,0.00011812151,0.004387777],"genre_scores_gemma":[0.9942971,0.00022806515,0.001312955,0.00096742896,0.0009607917,0.00002713496,0.000015084069,0.000043330703,0.0021481125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99797714,0.00029759284,0.00049413834,0.0002579407,0.0005775387,0.00039565083],"domain_scores_gemma":[0.99860036,0.00007593792,0.00035546094,0.00047769627,0.00023057406,0.00025995608],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006088695,0.00024016226,0.0002923918,0.00008980527,0.00071144535,0.00007689715,0.0002964661,0.00018144096,0.0014948142],"category_scores_gemma":[0.00022685865,0.0001473271,0.00017698991,0.00032452212,0.00031178645,0.00029118525,0.000043030104,0.0006811239,0.00020981707],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022059297,0.00031381115,0.00024085656,0.0000287405,0.00017592568,0.00025445083,0.001846394,0.000003339485,0.98846126,0.00060817844,0.0033370978,0.0025240357],"study_design_scores_gemma":[0.0039150147,0.00042440483,0.010251911,0.0008603027,0.0001306689,0.00034022654,0.0003862219,0.000083644896,0.9689876,0.010402935,0.0039975024,0.00021956683],"about_ca_topic_score_codex":0.000014384573,"about_ca_topic_score_gemma":0.000004557378,"teacher_disagreement_score":0.019473638,"about_ca_system_score_codex":0.0001282095,"about_ca_system_score_gemma":0.0003227945,"threshold_uncertainty_score":0.99941796},"labels":[],"label_agreement":null},{"id":"W3176572327","doi":"10.1096/fasebj.2019.33.1_supplement.700.14","title":"Hindlimb Denervation Alters the Regulation of Autophagy and Mitophagy","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mitophagy; Denervation; Autophagy; Mitochondrion; Mitochondrial biogenesis; Cell biology; Muscle atrophy; Hindlimb; Endocrinology; Atrophy; Biology; Internal medicine; Context (archaeology); Skeletal muscle; Chemistry; Anatomy; Biochemistry; Medicine; Apoptosis","score_opus":0.012301394247696077,"score_gpt":0.25340440068107606,"score_spread":0.24110300643337998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176572327","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99604326,0.001311784,0.00016468648,0.0014384732,0.00024448594,0.00019594996,0.000001655022,0.000009947234,0.0005897304],"genre_scores_gemma":[0.99760175,0.00015092625,0.00008653595,0.00095286925,0.00026712054,0.000001962595,0.0000031832994,0.00001032078,0.00092531065],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99925995,0.000084584135,0.00021209389,0.00007715712,0.00024936267,0.00011685782],"domain_scores_gemma":[0.99937344,0.00009055217,0.00018108531,0.00022716617,0.00007344452,0.00005429462],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039783886,0.00007873688,0.00013658381,0.00004653964,0.00012254574,0.00002181318,0.000099605255,0.00003868486,0.0002754741],"category_scores_gemma":[0.00002373081,0.000038984104,0.00007814764,0.000091990536,0.00008342578,0.00009368341,0.000017748873,0.00017898642,0.00001905311],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052480435,0.00007943551,0.022180025,0.000038078586,0.00023998592,0.000010863316,0.001359265,0.00017559362,0.9553951,0.0023451068,0.0008078824,0.01684384],"study_design_scores_gemma":[0.0019169541,0.0002952973,0.58301586,0.00009271739,0.00013683432,0.0005070165,0.000352757,0.0024371229,0.40674606,0.0036585915,0.0007640835,0.0000767165],"about_ca_topic_score_codex":0.00000862895,"about_ca_topic_score_gemma":7.059025e-7,"teacher_disagreement_score":0.56083584,"about_ca_system_score_codex":0.000025049969,"about_ca_system_score_gemma":0.00006610275,"threshold_uncertainty_score":0.30162483},"labels":[],"label_agreement":null},{"id":"W3176623634","doi":"10.1096/fasebj.2018.32.1_supplement.857.6","title":"Autophagy and mitophagy flux in skeletal muscle during chronic‐contractile activity","year":2018,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"York University","funders":"","keywords":"Autophagy; Mitophagy; TFEB; Skeletal muscle; Chemistry; Internal medicine; Endocrinology; Colchicine; Mitochondrion; Downregulation and upregulation; Bafilomycin; Flux (metallurgy); Biology; Medicine; Biochemistry; Apoptosis","score_opus":0.010628715014747816,"score_gpt":0.2712406909648229,"score_spread":0.26061197595007507,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176623634","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99596834,0.0018674387,0.00004188132,0.00045711882,0.00031886177,0.00017849836,0.0000037921209,0.00003182439,0.0011322525],"genre_scores_gemma":[0.9969963,0.00018852405,0.000041315525,0.00027474886,0.0016953041,0.0000061063306,0.000001007159,0.0000225492,0.00077414117],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99890906,0.00010127267,0.00021009994,0.00017663621,0.00023350195,0.00036944472],"domain_scores_gemma":[0.9993288,0.000066186505,0.000115536655,0.0002502068,0.000052120806,0.00018714853],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00031012762,0.0001556094,0.00023997466,0.000102048,0.00031184527,0.000050993378,0.0001246965,0.00007766419,0.0009501153],"category_scores_gemma":[0.00004468093,0.00010523412,0.00010034821,0.0001316053,0.00022403782,0.00021463461,0.00004469165,0.0005292627,0.00006981432],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003016163,0.00021745512,0.0023382546,0.000029398298,0.00011788409,0.0005885412,0.00060854387,0.0000032501587,0.96012026,0.000045388333,0.00016872665,0.035460707],"study_design_scores_gemma":[0.0029007932,0.00029444383,0.5288121,0.00007779488,0.00004576104,0.001197722,0.000085512496,0.00037705293,0.4649772,0.00024781056,0.000875371,0.00010843278],"about_ca_topic_score_codex":0.0000287443,"about_ca_topic_score_gemma":0.000026047454,"teacher_disagreement_score":0.5264738,"about_ca_system_score_codex":0.00015094568,"about_ca_system_score_gemma":0.00018475085,"threshold_uncertainty_score":0.99996316},"labels":[],"label_agreement":null},{"id":"W3176700052","doi":"10.1096/fasebj.2018.32.1_supplement.542.6","title":"mTOR‐dependent selective translation rapidly expands lysosome biogenesis, volume and retention capacity during phagocyte activatio","year":2018,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University; Toronto Metropolitan University","funders":"Canadian Institutes of Health Research; Ryerson University","keywords":"Lysosome; TFEB; Cell biology; Autophagy; PI3K/AKT/mTOR pathway; Endocytosis; Biology; ATG16L1; mTORC1; Endosome; Protein kinase B; Signal transduction; Cell; Biochemistry; Intracellular; Apoptosis","score_opus":0.027283716632591007,"score_gpt":0.26127860753413357,"score_spread":0.23399489090154257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176700052","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966623,0.0009319019,0.0011508929,0.00042579224,0.00022359012,0.00022288645,0.00001124753,0.000038970626,0.00033242474],"genre_scores_gemma":[0.99772245,0.0003840906,0.00017504195,0.00015532236,0.0011154537,0.0000068137424,0.000006928312,0.000020310923,0.0004136118],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891293,0.00012101221,0.0002408738,0.00017153923,0.00031988486,0.00023374648],"domain_scores_gemma":[0.99933153,0.000025218344,0.00016117698,0.0001653622,0.00015817326,0.00015853782],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003776878,0.00014547035,0.0001848562,0.00011828205,0.0005652359,0.000054277793,0.00007950967,0.00007703286,0.00027010537],"category_scores_gemma":[0.000021762578,0.00010019202,0.00013091599,0.00016230553,0.00015932806,0.00025782746,0.000011392409,0.00025822554,0.000019450774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011426602,0.00008138041,0.009072921,0.000019554764,0.00034086235,0.000021111657,0.0019789964,0.0000028245925,0.97960013,0.000019115585,0.0000705784,0.0076498576],"study_design_scores_gemma":[0.002650746,0.00035090107,0.17914563,0.00006609479,0.00023219429,0.00068444636,0.0002262681,0.00023278256,0.81566375,0.0005169053,0.00011038169,0.00011987354],"about_ca_topic_score_codex":0.000017195345,"about_ca_topic_score_gemma":0.000004422838,"teacher_disagreement_score":0.17007272,"about_ca_system_score_codex":0.00011030851,"about_ca_system_score_gemma":0.00007811649,"threshold_uncertainty_score":0.43473947},"labels":[],"label_agreement":null},{"id":"W3176948496","doi":"10.1096/fasebj.26.1_supplement.565.5","title":"The role of Parkin in the maintenance of normal mitochondrial and cellular function in skeletal muscle","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal","funders":"","keywords":"Parkin; Mitophagy; Skeletal muscle; Mitochondrion; Ubiquitin ligase; Cell biology; Biology; PINK1; Autophagy; Ubiquitin; Endocrinology; Internal medicine; Apoptosis; Parkinson's disease; Biochemistry; Medicine; Gene","score_opus":0.007441759394749489,"score_gpt":0.22474046474606724,"score_spread":0.21729870535131773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176948496","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925958,0.0061402665,0.000059876937,0.00031463482,0.0002079623,0.00014510681,0.0000021419294,0.0000016581183,0.00053253974],"genre_scores_gemma":[0.9991505,0.00027199712,0.000015894006,0.00010533991,0.00040400945,0.000004521153,0.0000010008514,0.0000056702825,0.000041073796],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99914247,0.00017199384,0.00024036336,0.00004429741,0.00020741987,0.00019343352],"domain_scores_gemma":[0.9995181,0.00012311543,0.00013297725,0.00015500466,0.000027177823,0.000043605105],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00081045844,0.000065305896,0.00012099905,0.000037741236,0.000079853744,0.000008538705,0.00011697701,0.000033116074,0.000040736555],"category_scores_gemma":[0.000040248422,0.000028337146,0.00006643868,0.00010402238,0.00013216247,0.00007695374,0.00001623721,0.00028113413,0.0000019157715],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001877162,0.0005968042,0.07854903,0.000025120002,0.00014741809,0.000036025634,0.008026582,0.000035455792,0.8421713,0.0028672474,0.0003521907,0.06531568],"study_design_scores_gemma":[0.0052526337,0.0005944576,0.8197935,0.00018381521,0.00018575926,0.00024926156,0.009663224,0.00045153155,0.15006422,0.0041961884,0.009235498,0.00012992173],"about_ca_topic_score_codex":0.000031285843,"about_ca_topic_score_gemma":0.000013379979,"teacher_disagreement_score":0.7412445,"about_ca_system_score_codex":0.000014783354,"about_ca_system_score_gemma":0.00003817416,"threshold_uncertainty_score":0.122140355},"labels":[],"label_agreement":null},{"id":"W3177128354","doi":"10.1096/fasebj.2019.33.1_supplement.719.10","title":"Atg16L1 Knockout Induces Insulin Resistance through Proteasomal IRS1 Degradation, Mediated by the Induction of ER Stress","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"IRS1; Insulin resistance; Protein kinase B; Insulin receptor; Endocrinology; Insulin receptor substrate; Internal medicine; Insulin; Autophagy; Chemistry; Downregulation and upregulation; Phosphorylation; IRS2; PI3K/AKT/mTOR pathway; Cell biology; Biology; Signal transduction; Medicine; Biochemistry; Apoptosis","score_opus":0.017769432661471962,"score_gpt":0.26613103167489616,"score_spread":0.2483615990134242,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3177128354","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908456,0.0039155087,0.000082014856,0.0030994336,0.00029689906,0.0005283566,0.00004011864,0.000021147005,0.0011709003],"genre_scores_gemma":[0.99627244,0.00046618964,0.00007508984,0.0004460834,0.0003344867,0.000014186144,0.00003513077,0.000020012918,0.002336354],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985678,0.00020869977,0.00036845304,0.00013680698,0.0005151747,0.00020304693],"domain_scores_gemma":[0.9988704,0.000119169934,0.00038657806,0.00035114295,0.00019650398,0.00007625501],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043270935,0.00014251324,0.00021963842,0.000039981704,0.00021703032,0.000032801796,0.0002624079,0.00009294206,0.0004928621],"category_scores_gemma":[0.00011077897,0.00007165058,0.000100260106,0.00024957943,0.00015054819,0.00022239827,0.000024848998,0.00055333565,0.000049200855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032395523,0.00086003105,0.019731477,0.00015759969,0.0011034954,0.00003829308,0.007317513,0.000056313944,0.93708396,0.0012016256,0.01964958,0.009560568],"study_design_scores_gemma":[0.0044285925,0.00037644783,0.060737558,0.0005054054,0.00024546223,0.0002021591,0.0033442262,0.00004955356,0.9210519,0.0022701006,0.006561451,0.00022714591],"about_ca_topic_score_codex":0.000029186704,"about_ca_topic_score_gemma":0.000006602874,"teacher_disagreement_score":0.04100608,"about_ca_system_score_codex":0.000052625837,"about_ca_system_score_gemma":0.00020529887,"threshold_uncertainty_score":0.5396494},"labels":[],"label_agreement":null},{"id":"W3177611695","doi":"10.1136/jim-2021-002016","title":"Autophagy and Cancer Metastasis: A Trojan Horse","year":2021,"lang":"en","type":"editorial","venue":"Journal of Investigative Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"","keywords":"Metastasis; Cancer; Epithelial–mesenchymal transition; Extracellular matrix; Cancer cell; Cancer research; Medicine; Pathology; Biology; Cell biology; Internal medicine","score_opus":0.03813771147682973,"score_gpt":0.3485536708054125,"score_spread":0.3104159593285828,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3177611695","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.052419767,0.25345236,0.0000487749,0.0124167865,0.6803868,0.00045672178,0.00016933061,0.00003664428,0.0006128057],"genre_scores_gemma":[0.0049350504,0.028148247,0.0009476701,0.002093533,0.961131,0.00002499347,0.00012296581,0.00010502629,0.0024915154],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.996017,0.00029599215,0.0012136825,0.0003874705,0.0017478399,0.00033801355],"domain_scores_gemma":[0.99471617,0.0005917571,0.0015154678,0.0003430896,0.0018660396,0.00096746936],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000955794,0.00053888373,0.0022469617,0.00047117876,0.00008563645,0.000024200588,0.00021392059,0.00051504467,0.00086227903],"category_scores_gemma":[0.0046311524,0.00035156714,0.00031370865,0.0004187056,0.0016448367,0.00014800868,0.00006195516,0.0020260622,0.0000029888868],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037247717,0.000120245975,0.00006598949,0.00052462623,0.002493773,0.002472868,0.0013897544,9.67459e-7,0.0061111804,0.00007012216,0.9803067,0.006071321],"study_design_scores_gemma":[0.008774269,0.0029252658,0.001030967,0.009901081,0.0053537223,0.00032566764,0.001478356,0.000012171317,0.012802494,0.0020877959,0.95492715,0.00038106495],"about_ca_topic_score_codex":0.000100370446,"about_ca_topic_score_gemma":0.000011097685,"teacher_disagreement_score":0.2807442,"about_ca_system_score_codex":0.0002469602,"about_ca_system_score_gemma":0.0031072511,"threshold_uncertainty_score":0.9998936},"labels":[],"label_agreement":null},{"id":"W3179932294","doi":"10.1111/jocs.15807","title":"Human cardiac ischemia‐reperfusion injury: Blunted stress response with age","year":2021,"lang":"en","type":"article","venue":"Journal of Cardiac Surgery","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; University of Toronto; York University","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Ischemia; Mitophagy; Autophagy; Internal medicine; Cardiology; Reperfusion injury; Anesthesia; Apoptosis","score_opus":0.012971818500877544,"score_gpt":0.285777159291716,"score_spread":0.27280534079083846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3179932294","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914708,0.0061353706,0.0000066792127,0.00049599266,0.00080491556,0.000101044236,0.000051260085,0.00002718018,0.0009067357],"genre_scores_gemma":[0.9963433,0.0008934237,0.00010310502,0.0004096375,0.001010216,0.0000045087195,0.000033339307,0.00004667657,0.0011557507],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99772966,0.00048154788,0.0005639921,0.00019988517,0.00074414856,0.0002807686],"domain_scores_gemma":[0.9978466,0.00043558815,0.00035504103,0.00043499874,0.00057557074,0.0003521986],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012746562,0.00021049335,0.0010825935,0.0002294168,0.00010031571,0.000040942054,0.000068121895,0.00013336012,0.00021391881],"category_scores_gemma":[0.0003084173,0.0001576899,0.0010414276,0.00037317327,0.0000907306,0.00015796108,0.000036838468,0.0004209425,0.000009070326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012859043,0.00040066824,0.09231978,0.00011419558,0.001981725,0.008721003,0.00033793598,0.0000058727946,0.8229784,0.000017553031,0.054022603,0.0062412247],"study_design_scores_gemma":[0.0006072944,0.00032623427,0.123635925,0.00083124766,0.00066913775,0.00028489062,0.0004932772,7.838977e-7,0.8328775,0.000024485826,0.03999831,0.00025088902],"about_ca_topic_score_codex":0.0000044831027,"about_ca_topic_score_gemma":2.730876e-7,"teacher_disagreement_score":0.03131615,"about_ca_system_score_codex":0.000104493905,"about_ca_system_score_gemma":0.00084650394,"threshold_uncertainty_score":0.6430408},"labels":[],"label_agreement":null},{"id":"W3183638065","doi":"10.1177/17590914211028364","title":"Mitochondrial and Organellar Crosstalk in Parkinson’s Disease","year":2021,"lang":"en","type":"article","venue":"ASN NEURO","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Indian Council of Medical Research","keywords":"Mitophagy; Autophagy; Cell biology; Mitochondrion; Endoplasmic reticulum; Crosstalk; Biology; Peroxisome; Unfolded protein response; PINK1; Proteostasis; ATG16L1; Organelle; Biochemistry; Apoptosis; Receptor","score_opus":0.010752728826105678,"score_gpt":0.2600794082485291,"score_spread":0.24932667942242343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3183638065","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953177,0.0019305532,0.000008821697,0.0016973076,0.0002615127,0.00013311389,0.000012079257,0.00003444196,0.00060444244],"genre_scores_gemma":[0.9942649,0.00046089073,0.00006937568,0.0039005072,0.00023419686,0.000009249106,0.000021398217,0.000020320798,0.0010191707],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9992955,0.00003732892,0.000121675315,0.0002571173,0.00012937195,0.00015905082],"domain_scores_gemma":[0.99942607,0.000063667234,0.000019353094,0.00024531526,0.000027418828,0.00021816097],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000020453495,0.00009336228,0.00014628396,0.000034565237,0.000034577875,0.000024094956,0.00003337895,0.00003577389,0.00030933344],"category_scores_gemma":[0.00017799546,0.00008811279,0.000044418375,0.0001347848,0.000045460725,0.000042924792,0.000034319786,0.000108656146,0.000029825515],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035839844,0.0019895714,0.6415074,0.00032202105,0.00016409477,0.06667687,0.0010797923,0.000014932448,0.24362352,0.0010354392,0.019174526,0.02082784],"study_design_scores_gemma":[0.0034296592,0.000080661535,0.8029454,0.000048217382,0.00006128023,0.00008576614,0.00003858986,0.00008717943,0.019527119,0.0006733223,0.1728787,0.00014411146],"about_ca_topic_score_codex":0.0000072623247,"about_ca_topic_score_gemma":0.000006139307,"teacher_disagreement_score":0.2240964,"about_ca_system_score_codex":0.000011905368,"about_ca_system_score_gemma":0.00013801284,"threshold_uncertainty_score":0.35931355},"labels":[],"label_agreement":null},{"id":"W3184397773","doi":"10.2139/ssrn.3409291","title":"NIX Mediates Mitophagy in Spinal Cord Injury in Rats by Interacting with LC3","year":2019,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Mitophagy; Spinal cord injury; Spinal cord; Neuroscience; Medicine; Autophagy; Psychology; Biology; Genetics","score_opus":0.0051991267217652536,"score_gpt":0.28633974290436137,"score_spread":0.2811406161825961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3184397773","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924472,0.0060542217,0.0000411475,0.00052951765,0.00021553245,0.00024339609,0.0000014647957,0.000018474679,0.00044905397],"genre_scores_gemma":[0.9961874,0.002328348,0.00003512586,0.0003563481,0.00021035201,0.000008718083,0.000008573406,0.000034481545,0.0008306765],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9975371,0.00007902011,0.00036406968,0.00023685023,0.00029017136,0.0014928201],"domain_scores_gemma":[0.99944645,0.000054796117,0.00016624358,0.00016756554,0.000045849087,0.000119092125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068560103,0.00019355041,0.00034981864,0.00025075526,0.00003783442,0.000025173344,0.00015390021,0.00008640973,0.00018141413],"category_scores_gemma":[0.000047330028,0.00014970523,0.00007197589,0.000293412,0.000032565316,0.00022719153,0.000019907277,0.0022385337,0.0000673143],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.041782416,0.0014466615,0.6580242,0.000114001945,0.0007057012,0.00061749906,0.00071437727,0.000020046085,0.08442639,0.0035065517,0.0006402812,0.2080019],"study_design_scores_gemma":[0.08132735,0.11194396,0.4702106,0.008923317,0.00056457816,0.013570272,0.028683696,0.0013143147,0.16701293,0.09855309,0.013666969,0.004228918],"about_ca_topic_score_codex":0.00009567522,"about_ca_topic_score_gemma":0.0002629662,"teacher_disagreement_score":0.20377298,"about_ca_system_score_codex":0.00078455015,"about_ca_system_score_gemma":0.0014848794,"threshold_uncertainty_score":0.97254395},"labels":[],"label_agreement":null},{"id":"W3184716687","doi":"10.3389/fcell.2021.708431","title":"Communication Between Autophagy and Insulin Action: At the Crux of Insulin Action-Insulin Resistance?","year":2021,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Insulin resistance; Insulin; Anabolism; Crosstalk; Adipose tissue; Biology; Endocrinology; Internal medicine; Cell biology; Medicine; Apoptosis; Biochemistry","score_opus":0.047832135521336756,"score_gpt":0.3312101601287619,"score_spread":0.28337802460742517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3184716687","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010092637,0.9875636,0.000049300936,0.00010245007,0.00034753466,0.000607868,0.00009626084,0.000020215537,0.0011200988],"genre_scores_gemma":[0.0026764814,0.99110264,0.0032512497,0.00011956707,0.00008675282,0.000090200185,0.0011887082,0.000028096558,0.0014562904],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980652,0.00037516886,0.0007556874,0.00045150897,0.000115140414,0.00023729501],"domain_scores_gemma":[0.99885726,0.00026356074,0.00037544244,0.00035127476,0.00004758098,0.000104906925],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030843687,0.00034050934,0.0014420485,0.00019924821,0.00018679333,0.000012857586,0.00018394542,0.0005216044,0.00012889385],"category_scores_gemma":[0.000044215456,0.00024441964,0.00014398598,0.0003349532,0.00044140988,0.000047354304,0.00024322992,0.00047770646,0.00001102552],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012885168,0.00010228744,0.001741486,0.002745138,0.00035547125,0.000013682924,0.00030439507,3.171663e-8,0.000019067656,0.000027491173,0.0043080794,0.99025404],"study_design_scores_gemma":[0.00123642,0.00006397686,0.003792373,0.0018275029,0.00031028755,0.000038533784,0.00046693152,9.921074e-7,0.0006559878,0.00026301364,0.99108523,0.00025876786],"about_ca_topic_score_codex":0.000028630524,"about_ca_topic_score_gemma":0.000039503615,"teacher_disagreement_score":0.98999524,"about_ca_system_score_codex":0.00028500863,"about_ca_system_score_gemma":0.0004520895,"threshold_uncertainty_score":0.99671435},"labels":[],"label_agreement":null},{"id":"W3185089369","doi":"10.1101/2021.07.19.452535","title":"Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Autophagy; Cell biology; Organelle; Ubiquitin; Lysosome; Galectin; Biology; Autophagosome; Receptor; Proteomics; Flux (metallurgy); Cathepsin; Chemistry; Biochemistry; Enzyme; Gene; Apoptosis","score_opus":0.017775384801868414,"score_gpt":0.26381485254518955,"score_spread":0.24603946774332114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3185089369","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99231875,0.0042298497,0.0002412854,0.00039031284,0.0004249671,0.0020306022,0.00027820907,0.00006773379,0.000018270957],"genre_scores_gemma":[0.99692875,0.0005097785,0.0017060583,0.0002849216,0.00014497098,0.00030714355,0.000003428518,0.000101847654,0.000013106797],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99597305,0.00097210746,0.0009984059,0.0007927956,0.000753704,0.00050994003],"domain_scores_gemma":[0.9960983,0.0005808199,0.0011115719,0.0015420697,0.0005378461,0.00012942303],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0021104321,0.00056368596,0.0012212155,0.0002748407,0.00013681746,0.00007662113,0.00073697616,0.0004983934,0.00009089685],"category_scores_gemma":[0.00093565776,0.00040282524,0.00037090728,0.001235985,0.00040307874,0.00014797912,0.00027826792,0.0013266942,0.000004679645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002859369,0.0006875636,0.021478146,0.00087201013,0.000607248,0.000064288244,0.00040847034,0.000016425636,0.97440195,0.0007250176,0.00045037206,0.00000256045],"study_design_scores_gemma":[0.0010965434,0.00020802296,0.14721933,0.0009290311,0.00030914918,9.540507e-8,0.00014318865,0.00010311104,0.8495143,0.00001189312,0.000116150375,0.00034916238],"about_ca_topic_score_codex":0.00012736203,"about_ca_topic_score_gemma":0.0000076044157,"teacher_disagreement_score":0.12574118,"about_ca_system_score_codex":0.0002536389,"about_ca_system_score_gemma":0.0011609355,"threshold_uncertainty_score":0.99984235},"labels":[],"label_agreement":null},{"id":"W3186709926","doi":"10.3389/fcell.2021.716208","title":"ORF3a-Mediated Incomplete Autophagy Facilitates Severe Acute Respiratory Syndrome Coronavirus-2 Replication","year":2021,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"School of Medicine, Shanghai Jiao Tong University; Science and Technology Commission of Shanghai Municipality; Fudan University; National Natural Science Foundation of China; Shanghai Municipal Health Commission; Shanghai Jiao Tong University; Shandong University","keywords":"Autophagy; Autophagosome; ATG16L1; Cell biology; Biology; Viral replication; Coronavirus; Virology; Coronavirus disease 2019 (COVID-19); Virus; Medicine; Genetics; Disease; Apoptosis","score_opus":0.02153752106600834,"score_gpt":0.27432398054637547,"score_spread":0.25278645948036715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3186709926","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903027,0.0061857454,0.00021330021,0.00016103193,0.00035505308,0.00024767825,0.00011959329,0.000061917606,0.002353003],"genre_scores_gemma":[0.9825296,0.0011063439,0.010581998,0.0028934528,0.000025394698,0.000060217284,0.00091983826,0.000019623985,0.0018635449],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986363,0.00009103124,0.0003449727,0.00054643705,0.00009073803,0.00029049802],"domain_scores_gemma":[0.9994438,0.00005526002,0.00006629725,0.0002400048,0.00004630155,0.00014831545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015076087,0.00018787924,0.00038689893,0.00012725515,0.00008343927,0.000009511153,0.00008260606,0.000192081,0.00024964943],"category_scores_gemma":[0.000044544195,0.00017234373,0.00004891991,0.00023516302,0.00016884351,0.000064500746,0.00009143481,0.0001752368,0.00007674559],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009380646,0.0005027834,0.6501408,0.00019577818,0.0005829805,0.0023319337,0.0013807084,0.0000010169693,0.2824102,0.00012692007,0.015202601,0.04618621],"study_design_scores_gemma":[0.006176353,0.00053374184,0.7542439,0.000084360276,0.00008371601,0.00095449097,0.001429733,0.00009335651,0.10200584,0.0026828717,0.13108143,0.00063022005],"about_ca_topic_score_codex":0.00001394458,"about_ca_topic_score_gemma":0.000004280517,"teacher_disagreement_score":0.18040437,"about_ca_system_score_codex":0.00014418476,"about_ca_system_score_gemma":0.00028414826,"threshold_uncertainty_score":0.7027973},"labels":[],"label_agreement":null},{"id":"W3188700951","doi":"10.1038/s41386-021-01116-0","title":"BDNF controls GABAAR trafficking and related cognitive processes via autophagic regulation of p62","year":2021,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; Campbell Family Mental Health Research Institute; National Institutes of Health; National Alliance for Research on Schizophrenia and Depression; U.S. Department of Defense","keywords":"Brain-derived neurotrophic factor; Neuroscience; Neurotrophic factors; Prefrontal cortex; GABAA receptor; Autophagy; GABAergic; Psychology; gamma-Aminobutyric acid; Neurotransmission; Internal medicine; Cognition; Biology; Medicine; Receptor; Inhibitory postsynaptic potential","score_opus":0.011767194354751537,"score_gpt":0.30515049059270727,"score_spread":0.2933832962379557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3188700951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99105763,0.004220997,0.00010670113,0.00068742863,0.00041688466,0.00044064282,0.000011999318,0.00009565891,0.002962047],"genre_scores_gemma":[0.9963898,0.0007286684,0.000049377002,0.0020272534,0.00011390585,0.000027880262,0.000034186734,0.000032314947,0.00059661403],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99871886,0.00016811807,0.0003639814,0.00037430457,0.00015863887,0.00021607548],"domain_scores_gemma":[0.9989321,0.00027260577,0.00017634677,0.00012543773,0.00035985306,0.00013364207],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008765478,0.00016445263,0.00039686868,0.00010206933,0.000063801075,0.0000074756595,0.000046082238,0.00011957971,0.0011531481],"category_scores_gemma":[0.00014439596,0.00015915491,0.00007328524,0.0003819055,0.00017038037,0.00007652443,0.000020340205,0.00022386597,0.000020246014],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017354905,0.00057870446,0.0013521533,0.00027266098,0.00035638435,0.0007907951,0.0005623819,0.00001989392,0.9782181,0.000098938464,0.00021433126,0.015800163],"study_design_scores_gemma":[0.03346387,0.0015402691,0.47872075,0.0003025946,0.0016852039,0.0022036596,0.00020462736,0.0030696855,0.47501945,0.0015016515,0.0018459533,0.00044226457],"about_ca_topic_score_codex":0.0000011343442,"about_ca_topic_score_gemma":4.84539e-7,"teacher_disagreement_score":0.5031986,"about_ca_system_score_codex":0.000012868517,"about_ca_system_score_gemma":0.00017602918,"threshold_uncertainty_score":0.9997599},"labels":[],"label_agreement":null},{"id":"W3190313776","doi":"10.1101/2021.08.05.455081","title":"Role of autophagy in sepsis-induced skeletal muscle dysfunction, whole-body metabolism, and survival","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre; Christie (Canada); Université du Québec à Montréal","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Genome Canada; Canadian Institutes of Health Research; McGill University Health Centre; Génome Québec; McGill University","keywords":"Autophagy; Sepsis; Skeletal muscle; Wasting; Biology; Endocrinology; Internal medicine; Muscle atrophy; Medicine; Immunology; Apoptosis; Biochemistry","score_opus":0.011268117515232903,"score_gpt":0.23701270455671622,"score_spread":0.2257445870414833,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3190313776","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98841125,0.009469414,0.00006898691,0.00013924568,0.0009120476,0.0006728779,0.000113387476,0.00018474583,0.000028057955],"genre_scores_gemma":[0.99784535,0.00064569415,0.00059372437,0.00018368593,0.00045698448,0.00013138902,0.000002558278,0.00013149978,0.000009099659],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.996956,0.00021728953,0.0007574649,0.0010260824,0.0005367868,0.0005063855],"domain_scores_gemma":[0.9974469,0.00007765327,0.00038382557,0.0012207562,0.00050498976,0.00036585517],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005065323,0.0005744972,0.0012324976,0.00041694177,0.000075331554,0.000083362895,0.00024313414,0.0006321942,0.00015373589],"category_scores_gemma":[0.00021848416,0.00061070215,0.00026947734,0.0006246117,0.00013085271,0.00016924576,0.00033973347,0.00084136525,0.00001425216],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000076998636,0.0005298222,0.0058225365,0.00060591084,0.0004296503,0.00021466722,0.00004370728,0.000009857797,0.9918013,0.00042484057,0.000017420962,0.000023275405],"study_design_scores_gemma":[0.0017290422,0.00006171298,0.6943283,0.0003811633,0.00031922606,4.4766015e-8,0.00003215154,0.00020692883,0.3015058,0.0000046858872,0.0010350805,0.00039584536],"about_ca_topic_score_codex":0.00018074761,"about_ca_topic_score_gemma":0.000010285147,"teacher_disagreement_score":0.6902955,"about_ca_system_score_codex":0.00014294735,"about_ca_system_score_gemma":0.0011956719,"threshold_uncertainty_score":0.99963444},"labels":[],"label_agreement":null},{"id":"W3190953210","doi":"10.3390/genes12081196","title":"Adding Some “Splice” to Stress Eating: Autophagy, ESCRT and Alternative Splicing Orchestrate the Cellular Stress Response","year":2021,"lang":"en","type":"review","venue":"Genes","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; ESCRT; splice; Alternative splicing; Fight-or-flight response; Stress (linguistics); Biology; Cellular stress response; Cell biology; Computational biology; Bioinformatics; Genetics; Gene; Exon; Endosome","score_opus":0.05953974817117222,"score_gpt":0.3624524055486285,"score_spread":0.3029126573774563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3190953210","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.051440477,0.9464931,0.000035618938,0.00011464436,0.0002927152,0.0011830524,0.00025782478,0.00007445911,0.00010813519],"genre_scores_gemma":[0.0010675901,0.9950118,0.00026915083,0.00032990458,0.0011716689,0.00025360996,0.00018934054,0.000117592775,0.0015893407],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99721485,0.0005564694,0.0005835993,0.00076360983,0.00040229058,0.00047917195],"domain_scores_gemma":[0.9977933,0.0006304818,0.00030849737,0.0008412025,0.00010312436,0.0003234065],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005087136,0.0006128151,0.0015647417,0.00020197648,0.00025998955,0.000106533094,0.00035368043,0.0002447531,0.00010613109],"category_scores_gemma":[0.00014022022,0.00039805597,0.0004015058,0.00036287162,0.000102903905,0.00008064253,0.00025983766,0.0004718131,0.000039631886],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021302553,0.00014701528,0.000054003314,0.008242717,0.0013781071,0.0015312288,0.0014857088,0.00002725089,0.0010043505,0.0005292945,0.00017329375,0.985214],"study_design_scores_gemma":[0.0010007255,0.00043015502,0.00024257755,0.057571556,0.0030571392,0.00019361294,0.0014782421,0.00011394982,0.014677837,0.00008434021,0.92006516,0.0010846775],"about_ca_topic_score_codex":0.00006840023,"about_ca_topic_score_gemma":0.000004770547,"teacher_disagreement_score":0.9841293,"about_ca_system_score_codex":0.00011917025,"about_ca_system_score_gemma":0.0005300486,"threshold_uncertainty_score":0.9998471},"labels":[],"label_agreement":null},{"id":"W3191748276","doi":"10.1093/humrep/deab130.207","title":"P–208 Oleic acid rescues altered autophagy induced by palmitic acid during mouse preimplantation development","year":2021,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute; London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"","keywords":"Autophagy; Palmitic acid; Blastocyst; Biology; Oleic acid; Andrology; Embryogenesis; Lipid droplet; Fatty acid; Embryo; Reproductive technology; Cell biology; Biochemistry; Apoptosis; Medicine","score_opus":0.030222367839145194,"score_gpt":0.2973798170703624,"score_spread":0.2671574492312172,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3191748276","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996907,0.001448527,0.000066592904,0.00019532144,0.00038765505,0.00036459073,0.000004914826,0.00028845624,0.00033691796],"genre_scores_gemma":[0.9931626,0.00009900249,0.00040214605,0.00012719556,0.00071684766,0.00008448196,0.00054483255,0.000044772747,0.00481814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99811083,0.00008910564,0.00041185284,0.00076323585,0.0003396771,0.00028532345],"domain_scores_gemma":[0.99886036,0.0000058979363,0.00013399987,0.0007040633,0.00016681664,0.00012884807],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017747185,0.00020538259,0.00026520714,0.000115566545,0.0003279777,0.000043634514,0.00006719534,0.000107326145,0.00030191225],"category_scores_gemma":[0.00007691543,0.00021045037,0.00007641382,0.00018850405,0.000034190787,0.00015975631,0.00003713557,0.0002104868,0.000085028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014170315,0.0002685667,0.0004161501,0.00016134894,0.00013859975,0.00006463496,0.0010905325,0.0000024679025,0.98982036,0.000039355113,0.00040439592,0.0074518705],"study_design_scores_gemma":[0.0013541136,0.00008809577,0.087335296,0.00008192749,0.00006898425,0.0002181234,0.00017987266,0.000003939097,0.9095566,0.00015804525,0.0007634907,0.00019148651],"about_ca_topic_score_codex":0.000010594732,"about_ca_topic_score_gemma":0.000007920758,"teacher_disagreement_score":0.08691915,"about_ca_system_score_codex":0.00017730115,"about_ca_system_score_gemma":0.00014630366,"threshold_uncertainty_score":0.85819167},"labels":[],"label_agreement":null},{"id":"W3193593859","doi":"10.21203/rs.3.rs-659023/v1","title":"Autophagy promotes cell survival by maintaining NAD(H) levels","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; LifeArc; Surgical Reconstruction and Microbiology Research Centre; LEO Fondet; National Institute for Health and Care Research; National Institutes of Health; Japan Society for the Promotion of Science; National Health and Medical Research Council; Cancer Research UK; Fundação de Amparo à Pesquisa do Estado de São Paulo; Wellcome Trust; Emerald Foundation; UK-India Education and Research Initiative","keywords":"Autophagy; NAD+ kinase; Cell biology; Cell survival; Chemistry; Cell; Biology; Biochemistry; Apoptosis; Enzyme","score_opus":0.08983013065220195,"score_gpt":0.4198457689897349,"score_spread":0.33001563833753295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3193593859","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96236724,0.0161268,0.0004243393,0.001434082,0.0005468119,0.002088321,0.00044328102,0.00029031278,0.016278801],"genre_scores_gemma":[0.9851555,0.0008160864,0.0005038247,0.00016981355,0.00071597175,0.00029096578,0.001246144,0.00015202201,0.010949657],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9938243,0.00094424764,0.00051656103,0.0011947921,0.0022572323,0.0012628849],"domain_scores_gemma":[0.99617225,0.000485777,0.0001292468,0.0014885456,0.000992885,0.00073128974],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0020898841,0.00047834875,0.00089318707,0.00037507797,0.00031724895,0.00028583844,0.0005454236,0.000702974,0.0039404775],"category_scores_gemma":[0.00053423847,0.0004486194,0.00044320044,0.0005098499,0.00027269367,0.000088275476,0.0012307612,0.0032370023,0.00020612266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005023169,0.022542208,0.04537657,0.065412425,0.008346171,0.049458276,0.03257054,0.00040445288,0.48273763,0.0060420586,0.15657674,0.12550975],"study_design_scores_gemma":[0.012323996,0.003738863,0.09560458,0.013591996,0.0005380117,0.00017293966,0.016344346,0.0040342784,0.7872437,0.01027263,0.05270307,0.0034315665],"about_ca_topic_score_codex":0.00032610702,"about_ca_topic_score_gemma":0.000013912349,"teacher_disagreement_score":0.3045061,"about_ca_system_score_codex":0.00048168056,"about_ca_system_score_gemma":0.0026755864,"threshold_uncertainty_score":0.99979657},"labels":[],"label_agreement":null},{"id":"W3194259761","doi":"10.1016/j.neulet.2021.136177","title":"GSK-3 mediates nuclear translocation of p62/SQSTM1 in MPTP-induced mouse model of Parkinson’s disease","year":2021,"lang":"en","type":"article","venue":"Neuroscience Letters","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Institutes of Health Research; Sun Yat-sen University","keywords":"MPTP; Neurodegeneration; Dopaminergic; Biology; Cell biology; GSK-3; Knockout mouse; Parkinson's disease; Neuroscience; Kinase; Dopamine; Internal medicine; Medicine; Biochemistry; Disease; Receptor","score_opus":0.029167329645281855,"score_gpt":0.2663175213257326,"score_spread":0.23715019168045076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3194259761","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99437565,0.00007203114,0.0002847295,0.004946636,0.00010168003,0.00015276836,0.000018420398,0.000023953275,0.00002413461],"genre_scores_gemma":[0.9902237,0.00017922914,0.0002093219,0.009312885,0.000021939084,0.0000080857635,0.000005076811,0.000016526794,0.000023203065],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988012,0.000048663616,0.00027306733,0.00030189092,0.00038103512,0.00019417032],"domain_scores_gemma":[0.9993621,0.000028282531,0.0000913365,0.00032825468,0.000040725587,0.000149262],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000095451476,0.00010479502,0.00021526332,0.000115087365,0.000028562485,0.0000075832677,0.0001457206,0.00003396949,0.000018174056],"category_scores_gemma":[0.00009764255,0.000100147525,0.00008887019,0.0003477395,0.00015702508,0.00013875551,0.000017757353,0.00011442929,0.0000020745595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011236744,0.0002603915,0.0055905012,0.0000642198,0.0000027125288,0.000049931794,0.00043405552,0.0012586147,0.9914055,0.00022174876,0.000038049056,0.0005619133],"study_design_scores_gemma":[0.0013532556,0.000082362974,0.080931,0.00009112219,0.00003617859,0.0000031392794,0.00007520076,0.03927334,0.8777839,0.00017432822,0.00006299489,0.00013319212],"about_ca_topic_score_codex":0.000014289233,"about_ca_topic_score_gemma":0.0000026170583,"teacher_disagreement_score":0.11362161,"about_ca_system_score_codex":0.000023245517,"about_ca_system_score_gemma":0.00015977852,"threshold_uncertainty_score":0.40838975},"labels":[],"label_agreement":null},{"id":"W3195516882","doi":"10.1101/2021.08.25.457684","title":"Selective localization of Mfn2 near PINK1 enable its preferential ubiquitination by Parkin on mitochondria","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Parkin; Mitophagy; PINK1; Ubiquitin; Ubiquitin ligase; MFN2; Mitochondrion; Cell biology; Chemistry; Biochemistry; Biology; mitochondrial fusion; Autophagy; Parkinson's disease; Mitochondrial DNA; Medicine","score_opus":0.011588917539273243,"score_gpt":0.23672110288804815,"score_spread":0.2251321853487749,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3195516882","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989184,0.0027224307,0.0049602874,0.00010445867,0.0010093012,0.0014144747,0.00028192575,0.00025971973,0.00006335291],"genre_scores_gemma":[0.9978216,0.00047347188,0.0005592832,0.00033603125,0.00041954947,0.0002165804,0.000016699945,0.00012597641,0.000030772404],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99728847,0.00020530263,0.0005964376,0.0008857043,0.0006236612,0.00040045482],"domain_scores_gemma":[0.99715066,0.00004991098,0.0005327934,0.0008311261,0.0011876522,0.00024784918],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023013532,0.00047631416,0.0007137315,0.00019563806,0.00013545407,0.000114660346,0.00022145329,0.00063054153,0.00028757504],"category_scores_gemma":[0.00025628053,0.000511368,0.0002128599,0.0005396987,0.000086996864,0.00013538192,0.00014095179,0.000615205,0.000031278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004667082,0.0011727052,0.0019114398,0.0014214851,0.00080518174,0.000038363014,0.000055373905,0.00035903038,0.99070555,0.0003249194,0.0027325915,0.000006672729],"study_design_scores_gemma":[0.0014258287,0.00025034606,0.014782303,0.0010283976,0.00037265292,1.6124007e-8,0.000004738244,0.0024305272,0.9767026,0.0000033738038,0.0025674573,0.00043177203],"about_ca_topic_score_codex":0.000031619184,"about_ca_topic_score_gemma":0.0000010530666,"teacher_disagreement_score":0.014002942,"about_ca_system_score_codex":0.00032708008,"about_ca_system_score_gemma":0.0011493831,"threshold_uncertainty_score":0.9997338},"labels":[],"label_agreement":null},{"id":"W3195893495","doi":"10.1016/j.coph.2021.07.013","title":"Autophagy in neuronal physiology and disease","year":2021,"lang":"en","type":"review","venue":"Current Opinion in Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Congressionally Directed Medical Research Programs; Kyoto University; U.S. Department of Defense","keywords":"Neuroscience; Autophagy; Homeostatic plasticity; Biology; Synaptic plasticity; Homeostasis; Neuroplasticity; Neurotransmission; Synapse; Synaptic scaling; Metaplasticity; Cell biology; Receptor","score_opus":0.11117216194970185,"score_gpt":0.4703176714072416,"score_spread":0.35914550945753976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3195893495","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00084085995,0.9890943,0.0000019319266,0.0001498344,0.008825387,0.0009638981,0.00006287204,0.00003306459,0.000027850285],"genre_scores_gemma":[0.00017010051,0.99704325,0.0000069601183,0.00026035297,0.0012175519,0.0004815793,0.00073199515,0.00004533993,0.000042868014],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974778,0.00055938715,0.0006724546,0.0007329691,0.00013245504,0.00042488542],"domain_scores_gemma":[0.99893373,0.0002251191,0.00018050053,0.0002338891,0.000031199466,0.00039558698],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00013432208,0.000416695,0.0017496541,0.00045747106,0.000027756189,0.000007574211,0.00014970516,0.00022264206,0.0010224737],"category_scores_gemma":[0.00005678432,0.00037524456,0.0002846337,0.00039465714,0.0001617015,0.000046161957,0.00016838146,0.0009276012,0.000040809646],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001510219,0.0012655084,0.00016361986,0.03787972,0.00014641361,0.00022729828,0.000041033956,0.0000019771244,0.000014947565,0.00051299215,0.00924081,0.95035464],"study_design_scores_gemma":[0.0021085301,0.00006715507,0.0021202308,0.00702906,0.00032696465,0.000056353405,0.0000023648172,0.0000628079,0.000002489026,0.00014536118,0.9878125,0.00026614234],"about_ca_topic_score_codex":0.000001630463,"about_ca_topic_score_gemma":1.3090337e-7,"teacher_disagreement_score":0.9785717,"about_ca_system_score_codex":0.00013231095,"about_ca_system_score_gemma":0.0011370823,"threshold_uncertainty_score":0.99989074},"labels":[],"label_agreement":null},{"id":"W3196648159","doi":"10.1016/j.bbadis.2021.166265","title":"Three dimensions of autophagy in regulating tumor growth: cell survival/death, cell proliferation, and tumor dormancy","year":2021,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"CancerCare Manitoba Foundation","keywords":"Autophagy; Biology; Programmed cell death; Cell growth; Cell biology; Tumor progression; Cancer research; Cancer cell; Cell; Cancer; Dormancy; Apoptosis; Genetics; Botany","score_opus":0.02068483346788283,"score_gpt":0.2921345198187199,"score_spread":0.2714496863508371,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3196648159","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.45680395,0.5410502,0.00002051903,0.000107983185,0.00008554126,0.0014129339,0.00036410315,0.000045411176,0.000109350476],"genre_scores_gemma":[0.49120933,0.50654936,0.0006725979,0.00022820086,0.000113407434,0.00019844687,0.0008023918,0.00019089914,0.00003535555],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9955977,0.00043175826,0.0015243519,0.001128889,0.0007868519,0.00053041126],"domain_scores_gemma":[0.996336,0.00020495387,0.0011390864,0.0013663858,0.00033821247,0.00061535765],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002722156,0.00092056295,0.0028511973,0.00056725624,0.0000898659,0.000044932105,0.0003921804,0.00022532485,0.000043201268],"category_scores_gemma":[0.00020234779,0.00076128595,0.0012359795,0.000966719,0.0002378857,0.0001358336,0.00031730617,0.0004763131,0.000006909452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024666702,0.027767096,0.00052456977,0.3202759,0.0051028687,0.0045930604,0.001051137,0.00001699653,0.5997602,0.0054696,0.0011011426,0.031870786],"study_design_scores_gemma":[0.006321778,0.0009525027,0.0064424044,0.039880723,0.012572996,0.000039551305,0.000091490176,0.00028339005,0.92745364,0.0011910936,0.0022055872,0.0025648165],"about_ca_topic_score_codex":0.000039673887,"about_ca_topic_score_gemma":0.000002498307,"teacher_disagreement_score":0.3276935,"about_ca_system_score_codex":0.00008548839,"about_ca_system_score_gemma":0.0015916413,"threshold_uncertainty_score":0.9994838},"labels":[],"label_agreement":null},{"id":"W3196990137","doi":"10.2139/ssrn.3915007","title":"Cross-Talk between STYK1 and EGFR in Autophagy Regulation and EGFR-TKIs Sensitivity in Non-Small Cell Lung Cancer","year":2021,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Autophagy; Lung cancer; Sensitivity (control systems); Epidermal growth factor receptor; Medicine; Cancer research; Cancer; Oncology; Internal medicine; Biology; Apoptosis; Genetics; Engineering","score_opus":0.006788551225364665,"score_gpt":0.2829190032629983,"score_spread":0.27613045203763364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3196990137","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.979752,0.01886524,0.00039991122,0.0005330671,0.00006342506,0.00018590766,0.0000063757643,0.000012677643,0.00018138776],"genre_scores_gemma":[0.99136215,0.007059257,0.00004928681,0.00015745223,0.0002997699,0.000006392296,0.000013735188,0.000026166681,0.0010258142],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99807066,0.000113700204,0.00031391496,0.00029080812,0.00018668818,0.0010242494],"domain_scores_gemma":[0.99945116,0.00007316374,0.000115604875,0.00014211638,0.0000784581,0.00013946804],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00092930655,0.00017287095,0.0003481462,0.00015158206,0.00009650829,0.00005072331,0.000039041828,0.00013883103,0.000054007334],"category_scores_gemma":[0.000027802513,0.00016777632,0.000060482904,0.00023609452,0.00005905888,0.00016350519,0.000035095312,0.0011853711,0.0000013429403],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022425925,0.00013831338,0.95581734,0.000103858925,0.00015075093,0.00049477734,0.0006662161,0.00008491798,0.018219253,0.00049928814,0.000010213115,0.023590818],"study_design_scores_gemma":[0.004075467,0.00013124547,0.9767751,0.00016650608,0.00009174845,0.00046956382,0.00031727858,0.0012763434,0.011128647,0.005333262,0.00006516704,0.00016965145],"about_ca_topic_score_codex":0.00044879594,"about_ca_topic_score_gemma":0.003567841,"teacher_disagreement_score":0.023421166,"about_ca_system_score_codex":0.000811423,"about_ca_system_score_gemma":0.001645092,"threshold_uncertainty_score":0.684172},"labels":[],"label_agreement":null},{"id":"W3197125680","doi":"10.1073/pnas.2025932118","title":"Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy","year":2021,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":196,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; Canadian Institutes of Health Research; University of Virginia; Canadian HIV Trials Network, Canadian Institutes of Health Research; Wellcome Trust; National Institutes of Health; Diabetes Canada; National Center for Research Resources; American Heart Association","keywords":"Mitophagy; AMPK; Skeletal muscle; Cell biology; Mitochondrion; Endoplasmic reticulum; Biology; Endocrinology; Autophagy; Biochemistry; Apoptosis; Protein kinase A","score_opus":0.02483694488903446,"score_gpt":0.3150530335835485,"score_spread":0.29021608869451404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197125680","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98848855,0.001937487,0.0000148785675,0.008864991,0.00003436561,0.00024238937,0.000020307774,0.000010704931,0.00038634212],"genre_scores_gemma":[0.995778,0.00022575307,0.0017530961,0.0017515315,0.0000645057,0.00002176094,3.8283022e-7,0.000006198651,0.00039876398],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99843127,0.000009199856,0.00029854657,0.00031876584,0.00076603895,0.00017615435],"domain_scores_gemma":[0.99912435,0.0001308071,0.00012020207,0.000015807143,0.00044366842,0.00016514563],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040040808,0.00011728485,0.00028561958,0.00019334666,0.00013459311,0.000029092402,0.00022371103,0.00009664735,0.000015328325],"category_scores_gemma":[0.00074606616,0.000082402614,0.000055269593,0.0008395084,0.00042072695,0.00011527371,0.00016805725,0.0001055289,7.1374177e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032347103,0.000101261256,0.004106886,0.00010592935,0.000043888136,2.636008e-7,0.0002898132,0.00003404618,0.9750137,0.016039504,0.00090784894,0.0030333863],"study_design_scores_gemma":[0.0007062047,0.000115107534,0.04705596,0.0004019172,0.00005089837,0.000011071014,0.00036180322,0.00027496053,0.9394834,0.010832632,0.0006221616,0.000083894134],"about_ca_topic_score_codex":0.000005058747,"about_ca_topic_score_gemma":1.6459869e-7,"teacher_disagreement_score":0.042949073,"about_ca_system_score_codex":0.000026798503,"about_ca_system_score_gemma":0.00008813052,"threshold_uncertainty_score":0.3360281},"labels":[],"label_agreement":null},{"id":"W3197398211","doi":"10.1136/jim-2021-002015","title":"Correspondence on ‘Role of AMPK/mTOR-independent autophagy in clear cell renal cell carcinoma’ by Radovanovic <i>et al</i>","year":2021,"lang":"en","type":"letter","venue":"Journal of Investigative Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"","keywords":"Autophagy; AMPK; PI3K/AKT/mTOR pathway; Renal cell carcinoma; RPTOR; Cancer research; Cell; Chemistry; Clear cell renal cell carcinoma; Cell biology; Discovery and development of mTOR inhibitors; Internal medicine; Oncology; Medicine; Biology; Apoptosis; Signal transduction; Biochemistry; Phosphorylation; Protein kinase A","score_opus":0.022472280707321986,"score_gpt":0.26800995621454643,"score_spread":0.24553767550722444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197398211","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.60813653,0.022039467,0.000038855364,0.3640768,0.0010303213,0.0006186566,0.00010118639,0.00002078161,0.003937383],"genre_scores_gemma":[0.33993563,0.0009158932,0.0003072352,0.652251,0.0016603443,0.00001144472,0.00020260966,0.0001271175,0.004588727],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99348336,0.0008513993,0.0019862347,0.0006239117,0.002472186,0.0005828978],"domain_scores_gemma":[0.9948825,0.0006954393,0.0024544569,0.00068951043,0.000742254,0.00053583074],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001233644,0.0007419593,0.002262457,0.000920999,0.000052639152,0.000016562703,0.0005780253,0.0005841989,0.0012292091],"category_scores_gemma":[0.00051103,0.00055748934,0.00045314326,0.00068149145,0.001165242,0.00015122445,0.00008462709,0.005182049,0.000028157481],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00086184946,0.00035343235,0.0005798047,0.00030847618,0.00013238612,0.0071523585,0.0012678955,0.000010549654,0.29922757,0.000012863397,0.6899748,0.000118017706],"study_design_scores_gemma":[0.011150221,0.007474366,0.004276197,0.005089036,0.0005440468,0.0005140058,0.0010366153,0.000053071042,0.57164764,0.0008407776,0.3968528,0.0005212132],"about_ca_topic_score_codex":0.00013047193,"about_ca_topic_score_gemma":0.0000038009296,"teacher_disagreement_score":0.293122,"about_ca_system_score_codex":0.000426976,"about_ca_system_score_gemma":0.0018215476,"threshold_uncertainty_score":0.9996877},"labels":[],"label_agreement":null},{"id":"W3198256784","doi":"10.1152/ajpgi.00221.2021","title":"Autophagy is required during high MUC2 mucin biosynthesis in colonic goblet cells to contend metabolic stress","year":2021,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; University of Calgary","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Autophagy; Mucin; Cell biology; Mucin 2; Endoplasmic reticulum; Homeostasis; Unfolded protein response; Biology; Biosynthesis; Chemistry; Biochemistry; Enzyme; Gene; Gene expression; Apoptosis","score_opus":0.008126793828725144,"score_gpt":0.2396091835657422,"score_spread":0.23148238973701707,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198256784","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99752766,0.0011769752,0.000019461733,0.0008902816,0.00012914922,0.00016117921,0.000053463056,0.00002100489,0.000020808619],"genre_scores_gemma":[0.9938714,0.0006318192,0.0029803969,0.0020007242,0.00036178026,0.000010345594,0.00001057445,0.000033329125,0.000099663666],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9976163,0.00037837864,0.00068610645,0.00053012953,0.00018118597,0.00060790265],"domain_scores_gemma":[0.99809045,0.00030136592,0.0005361221,0.000336111,0.00033379102,0.0004021682],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014669563,0.00035265676,0.0014045336,0.00028579394,0.00008682183,0.0000122603105,0.00021956507,0.000060767616,0.00043476035],"category_scores_gemma":[0.00013097662,0.00029270982,0.00026219024,0.00046229208,0.00060848705,0.00011358878,0.00014519786,0.0004653101,0.000032354834],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002388169,0.0005290668,0.0016642294,0.00007229889,0.0002472673,0.0007176175,0.00040408515,0.000066512344,0.99190176,0.00015581165,0.00011258757,0.0017405915],"study_design_scores_gemma":[0.0020486163,0.002964003,0.66636634,0.00038139938,0.00015866464,0.0017582688,0.00076777785,0.000064215026,0.32477382,0.00037116362,0.00013144173,0.00021429789],"about_ca_topic_score_codex":0.00023925012,"about_ca_topic_score_gemma":0.0000135042965,"teacher_disagreement_score":0.6671279,"about_ca_system_score_codex":0.0000635186,"about_ca_system_score_gemma":0.00027074086,"threshold_uncertainty_score":0.9999525},"labels":[],"label_agreement":null},{"id":"W3198853168","doi":"10.15252/embj.2021108863","title":"Autophagy in major human diseases","year":2021,"lang":"en","type":"review","venue":"The EMBO Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1549,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; Kenneth Rainin Foundation; National Cancer Institute; Cancer Research UK; Biotechnology and Biological Sciences Research Council; National Institute of Allergy and Infectious Diseases; Kennedy Trust for Rheumatology Research; Wellcome Trust; Bristol-Myers Squibb; AstraZeneca; Pfizer; National Institute on Aging","keywords":"Biology; Autophagy; Virology; Computational biology; Genetics; Apoptosis","score_opus":0.054851577235619994,"score_gpt":0.402436607474861,"score_spread":0.347585030239241,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198853168","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007355665,0.9969312,0.000004195499,0.00014602373,0.00041911384,0.00039421016,0.000021461125,0.00002900268,0.001319248],"genre_scores_gemma":[0.00015679504,0.9945236,0.000016744134,0.00037653345,0.0018210236,0.000035313693,0.00006828637,0.00006994204,0.0029317942],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99787503,0.00041456436,0.00071783137,0.00023526691,0.0003932642,0.00036404544],"domain_scores_gemma":[0.9986363,0.00012945241,0.00034855047,0.0005436729,0.000060198527,0.00028183326],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00035969637,0.0003558022,0.0016752915,0.00021586152,0.00022597767,0.000088534056,0.00037835722,0.0001436282,0.0027692346],"category_scores_gemma":[0.00007127457,0.00019615807,0.0010398683,0.00033272646,0.000089523004,0.000055554163,0.000076583136,0.0012463789,0.00012514426],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024876907,0.00045455544,0.000031882744,0.0036198725,0.0010516036,0.0074842935,0.00012967284,4.5915712e-7,0.000001949217,0.00090456154,0.008082776,0.9782135],"study_design_scores_gemma":[0.00093352573,0.00007936764,0.00032556435,0.018404115,0.0025615334,0.0042466833,0.000042522406,0.0000010760463,0.000003099684,0.0009244285,0.9722524,0.00022565048],"about_ca_topic_score_codex":0.0000049227924,"about_ca_topic_score_gemma":0.0000017882381,"teacher_disagreement_score":0.9779878,"about_ca_system_score_codex":0.00018979778,"about_ca_system_score_gemma":0.00091889885,"threshold_uncertainty_score":0.99814236},"labels":[],"label_agreement":null},{"id":"W3199065741","doi":"10.3390/cells10102517","title":"The Dual Role of Autophagy in Crizotinib-Treated ALK+ ALCL: From the Lymphoma Cells Drug Resistance to Their Demise","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Autophagy; Crizotinib; Context (archaeology); Cancer research; Programmed cell death; Biology; Cell biology; Chemistry; Medicine; Lung cancer; Apoptosis; Oncology; Biochemistry","score_opus":0.017564617771627985,"score_gpt":0.2895706695321788,"score_spread":0.2720060517605508,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3199065741","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004962316,0.9899066,0.0000021538563,0.00018199629,0.00038514324,0.0014404728,0.00037436024,0.000050175364,0.0026967786],"genre_scores_gemma":[0.0013689313,0.9888726,0.00007439455,0.00051315234,0.00037716934,0.00017765506,0.0002078312,0.00011620932,0.008292054],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99674326,0.00062101905,0.0010270744,0.00067080435,0.00041908585,0.00051878294],"domain_scores_gemma":[0.9957338,0.0018002604,0.00044114195,0.0016545658,0.00013849804,0.00023170789],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004988516,0.0005995298,0.0019494769,0.000085915664,0.00014381202,0.000056499393,0.0006951542,0.00030700234,0.00028557578],"category_scores_gemma":[0.00009535881,0.0003161281,0.00078101753,0.0006685344,0.00017056921,0.000033423185,0.00018089193,0.0003776235,0.000178081],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026498668,0.0005906069,0.00001762538,0.0020729296,0.001099368,0.0004894579,0.0019943435,0.000002732411,0.002039569,0.0002359914,0.03748364,0.95370877],"study_design_scores_gemma":[0.0007666606,0.000026164873,0.000067220215,0.009508357,0.0006720262,0.0000054583343,0.00029306626,0.0000044903622,0.030036837,0.00015073532,0.9581895,0.00027947727],"about_ca_topic_score_codex":0.00015192774,"about_ca_topic_score_gemma":0.00009779165,"teacher_disagreement_score":0.9534293,"about_ca_system_score_codex":0.00016316106,"about_ca_system_score_gemma":0.00076895184,"threshold_uncertainty_score":0.9999291},"labels":[],"label_agreement":null},{"id":"W3199690095","doi":"10.1007/s00005-021-00629-2","title":"Casein Kinase-1-Alpha Inhibitor (D4476) Sensitizes Microsatellite Instable Colorectal Cancer Cells to 5-Fluorouracil via Authophagy Flux Inhibition","year":2021,"lang":"en","type":"article","venue":"Archivum Immunologiae et Therapiae Experimentalis","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"National Institute for Medical Research Development; Silesian University of Technology; Shiraz University; Shiraz University of Medical Sciences","keywords":"Autophagy; Cancer research; Colorectal cancer; Apoptosis; Chemotherapy; Biology; Cancer; Microsatellite instability; Fluorouracil; Chemistry; Molecular biology; Gene; Biochemistry; Genetics","score_opus":0.0146250155710259,"score_gpt":0.29859246586551846,"score_spread":0.28396745029449255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3199690095","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97005504,0.023223985,0.0002094007,0.002110345,0.0012817472,0.0010415623,0.00038838174,0.00038243431,0.0013071212],"genre_scores_gemma":[0.9842696,0.0024655077,0.0023110087,0.0069810837,0.0005097298,0.00043647853,0.0009854782,0.00014887154,0.0018921938],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963194,0.00053127727,0.00070552656,0.0009981071,0.00050786015,0.0009378139],"domain_scores_gemma":[0.9982944,0.00015399189,0.00019600758,0.00076090277,0.0001999959,0.00039469256],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00028220183,0.00067097397,0.00079752237,0.00026502335,0.00038596577,0.00013911827,0.0001997111,0.00026937,0.0024482624],"category_scores_gemma":[0.000028354723,0.0006363724,0.00042242208,0.00059481844,0.000302403,0.0003332281,0.00028474617,0.00054489117,0.00039809634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020944371,0.0010975032,0.00012754956,0.000047392936,0.0006271479,0.0015096581,0.007186006,0.000009232836,0.9616229,0.00025382792,0.0023443666,0.02307996],"study_design_scores_gemma":[0.0037951923,0.0010150484,0.002399956,0.00024237977,0.0000841696,0.00036206385,0.00221979,0.000029909814,0.9759956,0.00025915535,0.012944166,0.00065258757],"about_ca_topic_score_codex":0.0006118641,"about_ca_topic_score_gemma":0.00005412654,"teacher_disagreement_score":0.02242737,"about_ca_system_score_codex":0.00046111003,"about_ca_system_score_gemma":0.0004851704,"threshold_uncertainty_score":0.99960876},"labels":[],"label_agreement":null},{"id":"W3199770540","doi":"10.1038/s41420-021-00641-7","title":"Axonal degeneration induces distinct patterns of phosphatidylserine and phosphatidylethanolamine externalization","year":2021,"lang":"en","type":"article","venue":"Cell Death Discovery","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"CIHR Skin Research Training Centre; Canada Research Chairs; U.S. Department of Health and Human Services; Government of Canada; Northwestern University; National Eye Institute","keywords":"Wallerian degeneration; Cell biology; Axon; Biology; Intracellular; Calcium in biology; Phosphatidylserine; Chemistry; Neuroscience; Biochemistry; Phospholipid; Membrane","score_opus":0.0143218430237611,"score_gpt":0.2505966499408883,"score_spread":0.2362748069171272,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3199770540","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9860052,0.0061034453,0.0067022424,0.00007139593,0.0001573835,0.00015675144,0.000053942982,0.000021344302,0.00072828133],"genre_scores_gemma":[0.9945607,0.0014370844,0.00031979172,0.00028355327,0.00015790241,0.000014609649,0.00043608565,0.000022195212,0.0027680492],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990611,0.000031864758,0.00027149444,0.00026103423,0.00023006974,0.0001444494],"domain_scores_gemma":[0.9994312,0.000036812784,0.00012198796,0.0002238094,0.00009682917,0.00008934743],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006159923,0.00015022306,0.0002503881,0.000041749536,0.000048416783,0.00003864038,0.00004375429,0.000065764136,0.00027672082],"category_scores_gemma":[0.000029635865,0.00013363823,0.00007320659,0.00010485955,0.000030750147,0.00026871357,0.00004484657,0.00007064492,0.000003437978],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027500017,0.0007408309,0.60167545,0.00069540367,0.00012074564,0.00023680148,0.00029053816,0.000025129399,0.3868004,0.0029473938,0.00006886518,0.0061234133],"study_design_scores_gemma":[0.0009783362,0.000085083375,0.3696598,0.000112895184,0.000079270314,0.000021435482,0.000040897914,0.00014267075,0.6284329,0.00017045163,0.00018388056,0.00009231081],"about_ca_topic_score_codex":0.00003329933,"about_ca_topic_score_gemma":0.000007859907,"teacher_disagreement_score":0.24163254,"about_ca_system_score_codex":0.00002421825,"about_ca_system_score_gemma":0.00011918865,"threshold_uncertainty_score":0.54496086},"labels":[],"label_agreement":null},{"id":"W3199851388","doi":"10.1016/j.chembiol.2021.07.017","title":"Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1","year":2021,"lang":"en","type":"article","venue":"Cell chemical biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto; University of British Columbia","funders":"Canadian Institutes of Health Research; Ontario Ministry of Research and Innovation; RIKEN; Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Research, Innovation and Science; Ministry of Education, Culture, Sports, Science and Technology; Canada Foundation for Innovation","keywords":"Autophagy; Mycobacterium tuberculosis; Biology; Small interfering RNA; Innate immune system; Biotinylation; Cell biology; Yeast; Saccharomyces cerevisiae; Phagosome; Microbiology; Tuberculosis; Immune system; RNA; Biochemistry; Gene; Phagocytosis; Genetics","score_opus":0.010337749966656535,"score_gpt":0.2627608339610778,"score_spread":0.25242308399442126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3199851388","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99095035,0.0064691,0.000015230571,0.0005629154,0.0002156885,0.00013048803,0.000041430645,0.00005311377,0.0015616805],"genre_scores_gemma":[0.99675643,0.0007239924,0.00053380005,0.00090793194,0.0002110098,0.00001515406,0.00037012875,0.000023415227,0.00045812756],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987094,0.000078631594,0.00030608533,0.00047172335,0.00007951827,0.0003546904],"domain_scores_gemma":[0.99931014,0.00013503213,0.000045973,0.00024760189,0.00006587167,0.00019539501],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009372225,0.00020583582,0.0004573093,0.00006341421,0.000026859714,0.000010582334,0.00006617744,0.00028882612,0.0007060596],"category_scores_gemma":[0.00007771298,0.00017961377,0.00009329775,0.00020305905,0.00017633967,0.000033317836,0.00012397375,0.00025175142,0.000043863864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017918905,0.0002919846,0.02682144,0.000109019806,0.000042918873,0.00035967227,0.00005088102,7.714439e-7,0.9709677,0.00015496042,0.00012542974,0.0008960336],"study_design_scores_gemma":[0.0024509474,0.00009636611,0.032921366,0.00003337653,0.00004571403,0.00006201397,0.000026863934,0.00012857093,0.95960027,0.0013440461,0.0030875837,0.0002028578],"about_ca_topic_score_codex":0.00002009764,"about_ca_topic_score_gemma":0.0000015816818,"teacher_disagreement_score":0.011367404,"about_ca_system_score_codex":0.000042253752,"about_ca_system_score_gemma":0.00007762115,"threshold_uncertainty_score":0.7730858},"labels":[],"label_agreement":null},{"id":"W3199873428","doi":"10.1042/bcj20210314","title":"Molecular mechanisms of mammalian autophagy","year":2021,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Autophagy; Cell biology; Ubiquitin; Proteasome; Biology; BAG3; Protein degradation; Endosome; Biochemistry; Chemistry; Gene; Intracellular","score_opus":0.009271151436984992,"score_gpt":0.26912410891798844,"score_spread":0.25985295748100345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3199873428","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9897237,0.0025873228,0.005708138,0.0007306306,0.0001400019,0.000041031974,0.000004368109,0.000015679636,0.0010491295],"genre_scores_gemma":[0.9943683,0.00007101823,0.0041168355,0.001025267,0.00014581688,0.0000012230412,0.000009742027,0.000014099187,0.00024769898],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991838,0.000027207765,0.00023303223,0.00011934861,0.0002739077,0.00016273749],"domain_scores_gemma":[0.99934566,0.000010520474,0.00006132047,0.00017865603,0.00015805564,0.0002458081],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007926331,0.000086824395,0.00020219192,0.00003712354,0.000025474466,0.000010505086,0.00007370698,0.000091866386,0.0010147714],"category_scores_gemma":[0.00006768091,0.00007331417,0.00020800752,0.00011554947,0.00004037319,0.000021582513,0.000027417558,0.00019408893,0.000016872355],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000068823334,0.00022883537,0.000037079786,0.000024938105,0.000100202546,0.0015222888,0.000016871172,8.2415755e-7,0.99316746,0.0030493909,0.00079727755,0.0009859786],"study_design_scores_gemma":[0.0010324805,0.00009059627,0.0009356494,0.00006614919,0.0000804758,0.0017225705,0.000037203125,0.00002543003,0.9875313,0.007916472,0.00049336074,0.00006830592],"about_ca_topic_score_codex":7.0278367e-7,"about_ca_topic_score_gemma":2.212427e-8,"teacher_disagreement_score":0.005636183,"about_ca_system_score_codex":0.000027561018,"about_ca_system_score_gemma":0.00020908954,"threshold_uncertainty_score":0.99989843},"labels":[],"label_agreement":null},{"id":"W3200035595","doi":"10.1080/15548627.2021.1973338","title":"Autophagy inhibition by TSSC4 (tumor suppressing subtransferable candidate 4) contributes to sustainable cancer cell growth","year":2021,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"CancerCare Manitoba Foundation","keywords":"Autophagy; Biology; Cell biology; Cancer; Cancer research; Cell growth; Genetics; Apoptosis","score_opus":0.005023659574405521,"score_gpt":0.25389724684547954,"score_spread":0.24887358727107403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3200035595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9696991,0.019582061,0.0012968971,0.0027135997,0.0004036034,0.00079852325,0.00020768435,0.0002978819,0.005000636],"genre_scores_gemma":[0.9668405,0.00070647354,0.00019117561,0.008750733,0.00021221647,0.0002575116,0.0003532295,0.000089734116,0.022598416],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971902,0.00012166462,0.00050213234,0.00073163916,0.00041660483,0.0010377798],"domain_scores_gemma":[0.99820685,0.00009337188,0.00009213784,0.0005216884,0.0005955883,0.00049034395],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002220626,0.00039732814,0.00066344516,0.00012359025,0.00036398554,0.00015784887,0.00014329409,0.00017360259,0.0029201836],"category_scores_gemma":[0.000091537804,0.00039405335,0.00020765155,0.0006277534,0.000084309126,0.00038902854,0.00008609614,0.00029164384,0.00010009477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00067703176,0.0010856382,0.0019439964,0.00081142277,0.00035120494,0.0043911915,0.0007668953,0.000033867924,0.9123549,0.006120586,0.07037476,0.0010885192],"study_design_scores_gemma":[0.00414923,0.00019158295,0.004143455,0.00018607557,0.00023344437,0.0000597155,0.0003630194,0.00015406648,0.9507304,0.0015710841,0.03783913,0.00037881974],"about_ca_topic_score_codex":0.002535724,"about_ca_topic_score_gemma":0.00009574652,"teacher_disagreement_score":0.03837549,"about_ca_system_score_codex":0.0005277733,"about_ca_system_score_gemma":0.000940294,"threshold_uncertainty_score":0.9998511},"labels":[],"label_agreement":null},{"id":"W3200416367","doi":"10.1242/bio.058736","title":"GRASP55 restricts early-stage autophagy and regulates spatial organization of the early secretory network","year":2021,"lang":"en","type":"article","venue":"Biology Open","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institute on Aging; Cancer Research Society","keywords":"Autophagy; Endoplasmic reticulum; Golgi apparatus; Biology; Cell biology; Unfolded protein response; Interactome; Secretory pathway; ATG8; Autophagosome; Biochemistry; Gene","score_opus":0.015477773136376395,"score_gpt":0.27224906206929284,"score_spread":0.25677128893291645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3200416367","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972872,0.0008934506,0.00006095121,0.00032935906,0.00022975623,0.00031689354,0.000012467311,0.000018620492,0.0008512908],"genre_scores_gemma":[0.99648005,0.00015737579,0.00015079352,0.00047341935,0.0001763299,0.0000057847146,0.00005688529,0.000014858038,0.0024845244],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99927896,0.00014232553,0.00017059287,0.00020330852,0.000060672908,0.00014414419],"domain_scores_gemma":[0.99935466,0.00005233642,0.000100724166,0.00032240205,0.00011004426,0.00005985351],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000111376845,0.000088539804,0.00021885658,0.00001717646,0.00009819742,0.00001702807,0.00016480846,0.00013402248,0.00034802],"category_scores_gemma":[0.00010678767,0.00006127614,0.000031897158,0.0002458391,0.0001423319,0.00004660094,0.00024223729,0.00009191814,0.0000072595],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012837711,0.000075059615,0.9617016,0.00002410772,0.00017262968,0.00003950607,0.00028607875,0.000006115874,0.028943626,0.005678016,0.0007223527,0.002222542],"study_design_scores_gemma":[0.0008704016,0.00012452157,0.948992,0.000038900067,0.00005006345,0.000011619882,0.000019606112,0.000018485334,0.04646681,0.0008423913,0.0025022894,0.0000629209],"about_ca_topic_score_codex":0.00045513807,"about_ca_topic_score_gemma":0.00002688467,"teacher_disagreement_score":0.01752318,"about_ca_system_score_codex":0.000011836427,"about_ca_system_score_gemma":0.00021256469,"threshold_uncertainty_score":0.38105747},"labels":[],"label_agreement":null},{"id":"W3200728597","doi":"10.1016/j.pharmthera.2021.107988","title":"Gut dysbiosis, defective autophagy and altered immune responses in neurodegenerative diseases: Tales of a vicious cycle","year":2021,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":191,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Department of Biotechnology, Ministry of Science and Technology, India","keywords":"Dysbiosis; Neuroinflammation; Gut flora; Neurodegeneration; Biology; Immune system; Gut–brain axis; Immunology; Autophagy; Immune dysregulation; Enteric nervous system; Inflammation; Disease; Neuroscience; Medicine; Pathology","score_opus":0.05273484474548461,"score_gpt":0.41311546558070317,"score_spread":0.36038062083521855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3200728597","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.038868174,0.95828193,0.000009875014,0.00012141222,0.0005042246,0.0017748051,0.00033407303,0.00005824922,0.000047226276],"genre_scores_gemma":[0.02406273,0.972941,0.00006145588,0.0017804606,0.00024283337,0.00050464657,0.00017570236,0.00010890319,0.0001222591],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963409,0.0013865617,0.00090838375,0.0006940062,0.00022150493,0.00044864605],"domain_scores_gemma":[0.997912,0.00083210965,0.00049149455,0.0004285795,0.00015260366,0.00018325198],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020656869,0.00063301617,0.002757737,0.00041218754,0.000088928675,0.000016680948,0.00022712997,0.0003703083,0.00019512337],"category_scores_gemma":[0.00002412248,0.00053856877,0.00057487254,0.0004992597,0.00047655113,0.00006434067,0.00015660403,0.000667887,0.000009695062],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021114904,0.0037642878,0.00032994564,0.011663558,0.012716083,0.001864853,0.0016793257,0.0000086657465,0.013432346,0.0002214554,0.00017960543,0.9520284],"study_design_scores_gemma":[0.013454961,0.0024185667,0.006334076,0.011456173,0.0547636,0.0010024898,0.00036637264,0.0003654547,0.012560064,0.00041313155,0.8948792,0.0019858992],"about_ca_topic_score_codex":0.000012023992,"about_ca_topic_score_gemma":0.0000032717521,"teacher_disagreement_score":0.9500425,"about_ca_system_score_codex":0.00016080475,"about_ca_system_score_gemma":0.0009751303,"threshold_uncertainty_score":0.99970657},"labels":[],"label_agreement":null},{"id":"W3200815443","doi":"10.1016/j.devcel.2021.08.019","title":"Endosomal trafficking and DNA damage checkpoint kinases dictate survival to replication stress by regulating amino acid uptake and protein synthesis","year":2021,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Probe Development and Commercialization","funders":"National Institutes of Health; Fondazione Italiana per la Ricerca sul Cancro; Associazione Italiana per la Ricerca sul Cancro","keywords":"Biology; Endosome; Cell biology; Kinase; Dephosphorylation; Hyperphosphorylation; DNA replication; Phosphorylation; Phosphatase; Integrated stress response; Autophagy; Biochemistry; Translation (biology); Intracellular; DNA; Gene","score_opus":0.01497179884774715,"score_gpt":0.24173596853598148,"score_spread":0.22676416968823432,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3200815443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969684,0.0005420391,0.000039864324,0.00026009756,0.00003032577,0.00040617195,0.000035346708,0.000064020336,0.0016537213],"genre_scores_gemma":[0.99502224,0.000043241587,0.0036535335,0.00016577308,0.00003760852,0.00008656212,0.000110778805,0.000029303896,0.0008509325],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987711,0.000046285182,0.00026968252,0.0004736951,0.00021294966,0.00022630481],"domain_scores_gemma":[0.9994335,0.000044286488,0.000073262265,0.00020780107,0.000040815186,0.00020032047],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014064109,0.00017677849,0.00023076615,0.00004751787,0.00014182796,0.000049257767,0.000050304407,0.00005663079,0.00007851368],"category_scores_gemma":[0.00009236291,0.00017397085,0.000031987645,0.00013253631,0.000046228073,0.00008202755,0.00008411011,0.00008416397,0.0000063212706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000104698156,0.00014541554,0.006353422,0.00016299546,0.000044721408,0.00010070705,0.0011483759,3.1549962e-7,0.96546984,0.00001801547,0.00005579521,0.026395686],"study_design_scores_gemma":[0.0006202239,0.000041608793,0.14536807,0.00020068724,0.000029540697,0.000029475772,0.0011796277,0.000031522948,0.8515186,0.000009965154,0.00080931664,0.00016136779],"about_ca_topic_score_codex":0.0000134589145,"about_ca_topic_score_gemma":0.000009260638,"teacher_disagreement_score":0.13901465,"about_ca_system_score_codex":0.00006201161,"about_ca_system_score_gemma":0.000084596795,"threshold_uncertainty_score":0.70943254},"labels":[],"label_agreement":null},{"id":"W3201064440","doi":"10.1101/2021.09.17.460825","title":"Basal Gp78-dependent mitophagy promotes mitochondrial health and limits mitochondrial ROS","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; University of British Columbia","funders":"University of British Columbia; Canadian Institutes of Health Research; Western Canada Research Grid; Compute Canada; Faculty of Medicine, University of British Columbia","keywords":"Mitophagy; Cell biology; Mitochondrion; Autophagy; ATG5; Mitochondrial fission; Biology; Autophagosome; Endoplasmic reticulum; FIS1; mitochondrial fusion; Apoptosis; Biochemistry; Mitochondrial DNA","score_opus":0.0166658179841521,"score_gpt":0.25543839200390156,"score_spread":0.23877257401974947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3201064440","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9670769,0.02022995,0.00070075784,0.0015461829,0.006657839,0.0028654204,0.0003175022,0.00059271674,0.000012755593],"genre_scores_gemma":[0.97413194,0.0027954215,0.012591778,0.0028036793,0.0066532823,0.00057089445,0.000009169546,0.00038032388,0.000063501284],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99434835,0.00036324363,0.0011003761,0.00206892,0.0010225618,0.0010965553],"domain_scores_gemma":[0.99505115,0.000116097544,0.0006737345,0.0019845725,0.0006242653,0.0015502116],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030865194,0.0010731121,0.0016922537,0.0003730005,0.0003188853,0.00043176816,0.0004602998,0.0010258786,0.00020170416],"category_scores_gemma":[0.00047563142,0.0011057395,0.00044839887,0.00042552673,0.00023462862,0.00021466911,0.0005219301,0.0015740797,0.00005230066],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010677668,0.0014023709,0.00433532,0.0025026123,0.0013274931,0.0013204799,0.00014696452,0.000007414129,0.9852494,0.0001756925,0.002430445,0.0000340558],"study_design_scores_gemma":[0.011567696,0.001344587,0.06766286,0.0034754702,0.0008370418,0.0000012497744,0.000052261068,0.00032662562,0.9068714,0.000015573241,0.0053342744,0.0025109625],"about_ca_topic_score_codex":0.00011127245,"about_ca_topic_score_gemma":0.000007701616,"teacher_disagreement_score":0.078377984,"about_ca_system_score_codex":0.0004542861,"about_ca_system_score_gemma":0.004303349,"threshold_uncertainty_score":0.99913925},"labels":[],"label_agreement":null},{"id":"W3202373309","doi":"10.7554/elife.72328","title":"Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy","year":2021,"lang":"en","type":"article","venue":"eLife","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":167,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Jane Coffin Childs Memorial Fund for Medical Research","keywords":"Autophagy; Cell biology; Lysosome; Biology; Organelle; Ubiquitin; Autophagosome; Galectin; Proteomics; Receptor; Flux (metallurgy); Chemistry; Biochemistry; Gene","score_opus":0.021549527226344643,"score_gpt":0.30745897067464983,"score_spread":0.2859094434483052,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3202373309","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995145,0.0022148928,0.00008673298,0.0009716107,0.00011246416,0.0005926991,0.000056404166,0.000016717358,0.0008034595],"genre_scores_gemma":[0.99778235,0.00021163386,0.00049378665,0.0007570931,0.00006789849,0.000047109977,0.00004083651,0.000021517992,0.00057776005],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99808735,0.0005255476,0.0004410729,0.0002351625,0.0004781755,0.00023269281],"domain_scores_gemma":[0.99840236,0.00062475336,0.00027612344,0.00043577363,0.00021098187,0.000050032526],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010028235,0.00016014295,0.0004433052,0.00007115205,0.00007907864,0.000012197612,0.00020618885,0.00009218503,0.00020761901],"category_scores_gemma":[0.0007498279,0.00009780541,0.0001540256,0.00066915643,0.00018046625,0.000083164494,0.000046045476,0.0003188089,0.000007714492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006591616,0.0010399657,0.047238328,0.00025157048,0.00044085446,0.00007289289,0.00997937,0.00001637249,0.9249807,0.005259863,0.00930517,0.00075573276],"study_design_scores_gemma":[0.0013689937,0.00027686072,0.06088523,0.00016409281,0.000086620224,0.000016846883,0.0022426974,0.00007222249,0.93370116,0.00048550917,0.0005897384,0.00011001313],"about_ca_topic_score_codex":0.0000521277,"about_ca_topic_score_gemma":0.0000225027,"teacher_disagreement_score":0.0136469,"about_ca_system_score_codex":0.00005264915,"about_ca_system_score_gemma":0.0002731105,"threshold_uncertainty_score":0.39883888},"labels":[],"label_agreement":null},{"id":"W3203222542","doi":"10.1080/15548627.2021.1972403","title":"Autophagy-dependent glutaminolysis drives superior IL21 production in HIV-1-specific CD4 T cells","year":2021,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University; Institut National de la Recherche Scientifique","funders":"Fonds de Recherche du Québec - Santé; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Autophagy; Glutaminolysis; Cell biology; Human immunodeficiency virus (HIV); Production (economics); Virology; Genetics; Biochemistry; Metabolism; Apoptosis; Glycolysis","score_opus":0.01353097128226494,"score_gpt":0.252488907446616,"score_spread":0.23895793616435107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203222542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98586726,0.008696343,0.0001296819,0.0011692432,0.0013667587,0.00053035084,0.000028294868,0.00026727683,0.0019448003],"genre_scores_gemma":[0.9776521,0.0018492225,0.0011365685,0.00065827963,0.00068138103,0.00010085516,0.00013005613,0.00008107057,0.017710516],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969264,0.00017124494,0.0006529569,0.0010033876,0.00060017174,0.00064578943],"domain_scores_gemma":[0.9983221,0.0000612357,0.00012204941,0.0010367164,0.00018296097,0.00027491988],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00024616398,0.0003986141,0.00069165515,0.0003140709,0.0001393895,0.00006967396,0.00020130053,0.00023712948,0.0030103975],"category_scores_gemma":[0.00007002124,0.00039251693,0.0003030788,0.0007607866,0.00014637258,0.0002664552,0.00010203471,0.0004256929,0.00088875083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003364894,0.0019036109,0.003817008,0.00018146752,0.000318028,0.0052681635,0.0022637278,0.00015374129,0.9428549,0.00105419,0.0030447873,0.0388039],"study_design_scores_gemma":[0.0023891388,0.00012043496,0.09558449,0.00012739123,0.00011458758,0.0002665816,0.00055030274,0.00016286211,0.88361007,0.00033760458,0.01636207,0.00037448163],"about_ca_topic_score_codex":0.000025030826,"about_ca_topic_score_gemma":0.000017552346,"teacher_disagreement_score":0.09176748,"about_ca_system_score_codex":0.00027257248,"about_ca_system_score_gemma":0.0003593791,"threshold_uncertainty_score":0.9998892},"labels":[],"label_agreement":null},{"id":"W3203574804","doi":"10.1126/sciadv.abj2485","title":"GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis","year":2021,"lang":"en","type":"article","venue":"Science Advances","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":126,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; National Institutes of Health; Cancer Research UK","keywords":"Folliculin; Biogenesis; Autophagy; Suppressor; Cell biology; Chemistry; Transcription (linguistics); Transcription factor; Biology; Biochemistry; Gene","score_opus":0.022006186360971014,"score_gpt":0.31184737167393706,"score_spread":0.28984118531296604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203574804","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921688,0.0021310062,0.0004383747,0.0032971296,0.00023943435,0.0003360578,0.000031108873,0.00009054581,0.001267551],"genre_scores_gemma":[0.9913586,0.000030807692,0.0028011051,0.0050052544,0.00012691911,0.000050693423,0.000010723583,0.000016346621,0.00059954857],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998091,0.000033587323,0.00017991546,0.0005169282,0.00070030714,0.000478307],"domain_scores_gemma":[0.9987497,0.000071322786,0.00006618238,0.0005750246,0.00024192904,0.00029588107],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022452194,0.0001735831,0.00024107762,0.000092457754,0.00044268975,0.00009060804,0.00038971784,0.000018055118,0.00035064647],"category_scores_gemma":[0.00008363629,0.0001024891,0.000066646884,0.0012137119,0.0008796357,0.00039548348,0.00008400672,0.00008024086,0.00007520401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035627017,0.00021371452,0.00972389,0.000055367444,0.000056582285,0.00065044424,0.0007472035,0.00061528076,0.9778298,0.0006779189,0.00048564584,0.00858785],"study_design_scores_gemma":[0.0008361837,0.00039501966,0.09559341,0.00008709968,0.000060707294,0.0002953535,0.0010610363,0.0002927279,0.87900573,0.00023293914,0.021905929,0.00023387774],"about_ca_topic_score_codex":0.000023171466,"about_ca_topic_score_gemma":0.000038342918,"teacher_disagreement_score":0.09882411,"about_ca_system_score_codex":0.000059303617,"about_ca_system_score_gemma":0.00060213153,"threshold_uncertainty_score":0.41793844},"labels":[],"label_agreement":null},{"id":"W3203743124","doi":"10.1101/2021.10.05.463117","title":"Ubr1-induced selective endo-phagy/autophagy protects against the endosomal and Ca <sup>2+</sup> -induced proteostasis disease stress","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Pohang University of Science and Technology; Seoul National University; California Institute of Technology","keywords":"Endosome; Autophagy; Cell biology; Proteostasis; ESCRT; BAG3; Ubiquitin; Lysosome; Biology; Ubiquitin ligase; Scaffold protein; Chemistry; Intracellular; Biochemistry; Apoptosis; Enzyme; Signal transduction; Gene","score_opus":0.01570898582009803,"score_gpt":0.23912084546320517,"score_spread":0.22341185964310714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203743124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98648286,0.004411999,0.00010688942,0.0006987019,0.0004443357,0.0067118322,0.0005325687,0.00058496883,0.000025862078],"genre_scores_gemma":[0.9927621,0.0005200555,0.0007815281,0.0011825778,0.0010848376,0.003326704,0.000007978321,0.00032021975,0.000013980498],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.993966,0.00064327545,0.00090249954,0.0021663865,0.0010937838,0.0012280734],"domain_scores_gemma":[0.99435633,0.00018485039,0.0006229299,0.0025400515,0.001026871,0.0012689861],"candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0005484237,0.0013408128,0.0013641507,0.0003864927,0.0006134598,0.00048551013,0.00069131254,0.0008107655,0.000098094846],"category_scores_gemma":[0.00082565466,0.0011297347,0.0005137738,0.00095177605,0.00024533522,0.0002849138,0.0007910893,0.0022518474,0.0000381321],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016963371,0.0022766942,0.0056760767,0.0040652365,0.0043897703,0.0060470067,0.00053241337,0.00024135457,0.9743954,0.000279221,0.00017465002,0.0002258739],"study_design_scores_gemma":[0.0034405666,0.0002990951,0.12999228,0.001601802,0.0010417489,4.887943e-7,0.000068056084,0.0030584792,0.85892785,0.000006597654,0.00024387825,0.0013191926],"about_ca_topic_score_codex":0.00013620821,"about_ca_topic_score_gemma":0.0000026860093,"teacher_disagreement_score":0.1243162,"about_ca_system_score_codex":0.00050825655,"about_ca_system_score_gemma":0.0036604083,"threshold_uncertainty_score":0.9999343},"labels":[],"label_agreement":null},{"id":"W3204151227","doi":"10.34172/jnp.2022.01","title":"Autophagy and treatment of patients with COVID-19; which drugs target the autophagy pathway?","year":2021,"lang":"en","type":"article","venue":"Journal of Nephropathology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Systems, Applications & Products in Data Processing (Canada)","funders":"","keywords":"Autophagy; Medicine; Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Pharmacology; Virology; Intensive care medicine; Apoptosis; Internal medicine; Disease; Biology; Infectious disease (medical specialty); Biochemistry","score_opus":0.011957355766818873,"score_gpt":0.2725460736964211,"score_spread":0.2605887179296022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204151227","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912227,0.005698481,0.000350986,0.0019967265,0.00020770797,0.00021053712,0.000032173306,0.000012525519,0.00026816403],"genre_scores_gemma":[0.99480116,0.0007949954,0.0014455032,0.0024518797,0.0002067957,0.0000072324056,0.000017661689,0.000023730241,0.00025105313],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984995,0.00025239188,0.000503425,0.00019331845,0.0003236829,0.00022764338],"domain_scores_gemma":[0.99820185,0.00019455366,0.0004742526,0.00032006187,0.00051951536,0.00028977223],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022432467,0.00019195382,0.0006174159,0.000112843576,0.00010131168,0.0000117917625,0.00009414302,0.00010691432,0.00034307584],"category_scores_gemma":[0.00016543432,0.00010467113,0.00013947074,0.00023808924,0.00023074044,0.000077591554,0.000030493453,0.00017132812,0.0000033931333],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.033017665,0.02800142,0.5882771,0.001041978,0.007409144,0.05282121,0.05513238,0.00065391004,0.08411407,0.009801882,0.008301199,0.13142806],"study_design_scores_gemma":[0.018416554,0.009360453,0.8768862,0.00007478283,0.00068493414,0.0038948916,0.00092262443,0.000067035624,0.024427447,0.0014081782,0.06362384,0.00023306692],"about_ca_topic_score_codex":0.000006375518,"about_ca_topic_score_gemma":0.0000031569266,"teacher_disagreement_score":0.28860912,"about_ca_system_score_codex":0.00011779485,"about_ca_system_score_gemma":0.0010570218,"threshold_uncertainty_score":0.4268365},"labels":[],"label_agreement":null},{"id":"W3204629517","doi":"10.1016/j.mam.2021.101041","title":"Role of autophagy in muscle disease","year":2021,"lang":"en","type":"review","venue":"Molecular Aspects of Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Autophagy; Wasting; Lysosome; Sarcopenia; Cell biology; Biology; Myostatin; Disease; Skeletal muscle; Insulin resistance; Medicine; Endocrinology; Obesity; Internal medicine; Apoptosis; Biochemistry","score_opus":0.017058239093209644,"score_gpt":0.3320442682659204,"score_spread":0.31498602917271074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204629517","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00068816665,0.9919542,0.000020304888,0.00016301079,0.00011239786,0.0008184694,0.00002887482,0.000026193728,0.0061883647],"genre_scores_gemma":[0.017186735,0.9818683,0.000068311805,0.00017822275,0.00016867054,0.00004992453,0.00029360663,0.00008329593,0.00010289654],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972644,0.00019310694,0.001072117,0.00048337632,0.000693512,0.00029353],"domain_scores_gemma":[0.9979279,0.000105093015,0.00047057137,0.0010047527,0.0001444529,0.00034719624],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002703689,0.000427789,0.0033164239,0.00051736913,0.000012029316,0.0000021383864,0.0002513125,0.00022624503,0.0007497646],"category_scores_gemma":[0.00045405238,0.0003295314,0.00068295165,0.00076903385,0.000290569,0.000024192661,0.00008221519,0.00038276386,0.0000091424945],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000067863075,0.0008728783,0.000008958081,0.030400952,0.0007128386,0.0073214155,0.00012902323,0.0000021086817,0.0016518434,0.010963271,0.00019227015,0.9476766],"study_design_scores_gemma":[0.005583506,0.000817,0.0010863353,0.15198821,0.006773085,0.00015405842,0.00014019193,0.000026307618,0.0024567686,0.0033458518,0.8270096,0.0006190852],"about_ca_topic_score_codex":0.000055816454,"about_ca_topic_score_gemma":0.0000021448916,"teacher_disagreement_score":0.9470575,"about_ca_system_score_codex":0.00008451985,"about_ca_system_score_gemma":0.0010237502,"threshold_uncertainty_score":0.99991566},"labels":[],"label_agreement":null},{"id":"W3204750817","doi":"10.1016/b978-0-12-822003-0.00005-x","title":"Regulation of autophagy—transcriptional, posttranscriptional, translational, and posttranslational mechanisms","year":2021,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Autophagy; Cell biology; TFEB; BAG3; PI3K/AKT/mTOR pathway; ATG16L1; Lysosome; AMPK; Biology; Post-translational regulation; ULK1; Ubiquitin; Translational regulation; Epigenetics; Phosphorylation; Autophagy-related protein 13; Chemistry; Signal transduction; Protein kinase A; Translation (biology); Biochemistry; Messenger RNA; Gene; Protein phosphorylation; Enzyme; Apoptosis","score_opus":0.021672833502071904,"score_gpt":0.25676138400237014,"score_spread":0.23508855050029823,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204750817","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0027439347,0.026327401,0.000894693,0.0013656908,0.00044389788,0.0015210874,0.0013520085,0.00014441337,0.96520686],"genre_scores_gemma":[0.07274091,0.0009876834,0.0049238224,0.0010012642,0.00036645093,0.00004373931,0.0025350368,0.00017363709,0.91722745],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971305,0.000040264258,0.0008980657,0.000654715,0.001024028,0.00025241674],"domain_scores_gemma":[0.9984493,0.00009008979,0.0002816951,0.00043006885,0.00050707697,0.00024172221],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002144393,0.00053994794,0.0008626586,0.0003277338,0.0001416674,0.000027689186,0.00011205896,0.00058435206,0.0041013123],"category_scores_gemma":[0.000008196173,0.00055949506,0.0005971925,0.000038018345,0.0003069838,0.00010784357,0.000015092173,0.000439518,0.000019228513],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046380828,0.0001150634,0.000015571353,0.0007008117,0.0010830171,0.00006365441,0.00032181095,0.000008020757,0.094475955,0.6916361,0.000060446608,0.21105577],"study_design_scores_gemma":[0.004900884,0.0005168292,0.017953046,0.002653789,0.002356432,0.0005784458,0.00002319414,0.00018778154,0.009335411,0.40196106,0.5583558,0.0011773384],"about_ca_topic_score_codex":5.5826075e-7,"about_ca_topic_score_gemma":0.0000035479338,"teacher_disagreement_score":0.5582953,"about_ca_system_score_codex":0.000052083407,"about_ca_system_score_gemma":0.00063922914,"threshold_uncertainty_score":0.99968565},"labels":[],"label_agreement":null},{"id":"W3204948040","doi":"10.1016/j.jcmgh.2021.09.017","title":"Rab9 Mediates Pancreatic Autophagy Switch From Canonical to Noncanonical, Aggravating Experimental Pancreatitis","year":2021,"lang":"en","type":"article","venue":"Cellular and Molecular Gastroenterology and Hepatology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; U.S. Department of Veterans Affairs","keywords":"Autophagy; ATG5; Cell biology; Autophagosome; Pancreatitis; Biology; Internal medicine; Medicine; Apoptosis; Biochemistry","score_opus":0.007786074046003461,"score_gpt":0.25280618821360185,"score_spread":0.2450201141675984,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204948040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9859934,0.009503221,0.0024820105,0.0013629533,0.00015812309,0.00021875788,0.00002349916,0.000045060046,0.0002129958],"genre_scores_gemma":[0.98837614,0.0005209521,0.0017748309,0.008894277,0.000090591886,0.00006133179,0.00018976923,0.000030523002,0.00006160362],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99822646,0.00021523915,0.00033942127,0.00061407074,0.00012450716,0.0004802688],"domain_scores_gemma":[0.9990403,0.000081535065,0.00006732718,0.00031257494,0.00005770883,0.000440574],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008457344,0.0002576227,0.00069319963,0.00007137231,0.000120643985,0.000020908627,0.00007414243,0.00022106891,0.00033668478],"category_scores_gemma":[0.00006587655,0.0002504168,0.00011067438,0.00007158115,0.00024739784,0.000029533467,0.00015322397,0.00024249678,0.000014432061],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000789944,0.00028587985,0.222222,0.000037700138,0.00047957394,0.0070673013,0.0003532705,9.028019e-7,0.7671222,0.0006575151,0.00019424858,0.00078946864],"study_design_scores_gemma":[0.0072465786,0.0023718753,0.06500243,0.00011642671,0.0007151412,0.0025021073,0.00035497328,0.00057847355,0.91786367,0.00064337865,0.0022408029,0.00036417312],"about_ca_topic_score_codex":0.00020711779,"about_ca_topic_score_gemma":0.00007637679,"teacher_disagreement_score":0.15721957,"about_ca_system_score_codex":0.000028251312,"about_ca_system_score_gemma":0.00014103542,"threshold_uncertainty_score":0.9999948},"labels":[],"label_agreement":null},{"id":"W3207994331","doi":"10.3389/fcell.2021.712124","title":"Canonical and Non-canonical TGFβ Signaling Activate Autophagy in an ULK1-Dependent Manner","year":2021,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; PI3K/AKT/mTOR pathway; mTORC2; Autophagy-related protein 13; Phosphorylation; Protein kinase A; ULK1; Mechanistic target of rapamycin; Autophagosome; p38 mitogen-activated protein kinases; Biology; AMPK; Cancer research; Signal transduction; Chemistry; mTORC1; Mitogen-activated protein kinase kinase; Biochemistry; Apoptosis","score_opus":0.010742207715784527,"score_gpt":0.2589579217403375,"score_spread":0.24821571402455297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3207994331","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99475133,0.0025589317,0.00019498721,0.00015283174,0.00031946477,0.00016993066,0.0000074141344,0.000016282878,0.0018288435],"genre_scores_gemma":[0.9898565,0.0006614097,0.007902029,0.0009099283,0.00005176343,0.000021920257,0.00008204959,0.00001555871,0.00049885805],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9986699,0.000091813614,0.0003114326,0.0004878555,0.00008409741,0.00035487206],"domain_scores_gemma":[0.9995821,0.00004291521,0.000039088416,0.00011119628,0.00001975795,0.00020495166],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016119685,0.00018384485,0.00041346616,0.0001298196,0.00005924271,0.000015484035,0.0000640844,0.00023135691,0.00012813376],"category_scores_gemma":[0.000015192958,0.00016280625,0.000031831572,0.0001317345,0.00015974375,0.000070609254,0.00010151376,0.00027247917,0.000005667738],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00080388767,0.0005474475,0.75056916,0.00008067796,0.000086099964,0.0015114269,0.0012038803,0.0000033973515,0.22507243,0.0000773999,0.000459923,0.019584294],"study_design_scores_gemma":[0.008398316,0.00043377842,0.57450235,0.00011924387,0.000040636507,0.00025192878,0.002922847,0.00034232784,0.40748394,0.001825074,0.0031247132,0.00055484666],"about_ca_topic_score_codex":0.000056737113,"about_ca_topic_score_gemma":0.00008583068,"teacher_disagreement_score":0.18241152,"about_ca_system_score_codex":0.00012879103,"about_ca_system_score_gemma":0.0004036569,"threshold_uncertainty_score":0.6639046},"labels":[],"label_agreement":null},{"id":"W3211706716","doi":"10.1111/acel.13514","title":"Adiponectin alleviated Alzheimer‐like pathologies via autophagy‐lysosomal activation","year":2021,"lang":"en","type":"article","venue":"Aging Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Natural Science Foundation of China","keywords":"Autophagy; Neuroinflammation; Adiponectin; AMPK; PI3K/AKT/mTOR pathway; Biology; Signal transduction; Cell biology; Endocrinology; Cancer research; Internal medicine; Medicine; Phosphorylation; Inflammation; Immunology; Protein kinase A; Apoptosis; Biochemistry","score_opus":0.02173107136571244,"score_gpt":0.27660592093681957,"score_spread":0.2548748495711071,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3211706716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98367494,0.004860583,0.0009768138,0.0010420558,0.00039938456,0.00019816803,0.0000034320733,0.00038800645,0.008456586],"genre_scores_gemma":[0.99415535,0.00016798274,0.0009930228,0.0023154274,0.00017796205,0.000015518568,0.00012134257,0.000034598626,0.0020187905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988815,0.00007708403,0.00020714177,0.00034115367,0.00020988748,0.00028319017],"domain_scores_gemma":[0.99922466,0.00008165081,0.00008423849,0.0003870892,0.000112363574,0.00010999714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010231625,0.00017306136,0.00024071902,0.00006721885,0.00010819664,0.00002556462,0.00007650244,0.00010827604,0.00061865326],"category_scores_gemma":[0.000038522976,0.00016221583,0.0001237277,0.00023693536,0.000040274084,0.00010986296,0.000049900747,0.00021211096,0.0001921769],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016457413,0.0007023684,0.0041447864,0.000088137895,0.0004734327,0.0017607113,0.0011569948,0.000051538416,0.9489725,0.00008875371,0.0036078624,0.0387883],"study_design_scores_gemma":[0.001602965,0.0001097799,0.04181653,0.00007752567,0.0002776907,0.00007612673,0.0002153539,0.0005583247,0.94746584,0.00036682357,0.0072103003,0.00022275036],"about_ca_topic_score_codex":0.00002780095,"about_ca_topic_score_gemma":0.00000141274,"teacher_disagreement_score":0.03856555,"about_ca_system_score_codex":0.000037279417,"about_ca_system_score_gemma":0.00013235476,"threshold_uncertainty_score":0.67738193},"labels":[],"label_agreement":null},{"id":"W3212080381","doi":"10.1186/s13062-021-00311-9","title":"Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins","year":2021,"lang":"en","type":"article","venue":"Biology Direct","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Autophagy; Effector; Biology; Cell biology; Endoplasmic reticulum; Rab; GTPase; Mitochondrion; Intracellular; Small GTPase; Lysosome; Organelle; Biochemistry; Signal transduction; Apoptosis","score_opus":0.02088707482926688,"score_gpt":0.2972582302576781,"score_spread":0.27637115542841123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3212080381","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99309325,0.0031892105,0.000048915503,0.00084193476,0.00045232996,0.0009473308,0.0000899988,0.0001392527,0.0011977671],"genre_scores_gemma":[0.9928417,0.00019566514,0.00029641925,0.00064330787,0.00014905665,0.00014063867,0.00036307666,0.000029120167,0.0053410153],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99845445,0.00036598282,0.00034165283,0.0003975553,0.00015340446,0.00028694744],"domain_scores_gemma":[0.9988674,0.00024562335,0.00014343848,0.00034079852,0.00024892425,0.00015384947],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020949231,0.00019958228,0.00060027675,0.00012106123,0.000057780126,0.0000074291725,0.00009353773,0.00025068293,0.0007013381],"category_scores_gemma":[0.0012535293,0.00015960069,0.00019597291,0.00043950343,0.00005872003,0.000039442704,0.000034214198,0.0001274254,0.0001244955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044065694,0.00048671657,0.0047314926,0.000097028074,0.00040407907,0.000073098716,0.00010439527,0.000002074421,0.9906992,0.00014751646,0.001069994,0.0017437764],"study_design_scores_gemma":[0.0022190271,0.0006424337,0.054800037,0.00017031918,0.00020171468,0.000012349676,0.000011524248,0.000037539216,0.9356783,0.000039864615,0.0060235863,0.00016332169],"about_ca_topic_score_codex":0.000040474417,"about_ca_topic_score_gemma":0.000018334997,"teacher_disagreement_score":0.055020887,"about_ca_system_score_codex":0.00007942697,"about_ca_system_score_gemma":0.00021986713,"threshold_uncertainty_score":0.7679161},"labels":[],"label_agreement":null},{"id":"W3214333524","doi":"10.1155/2021/7918693","title":"Identification of Autophagy‐Related Prognostic Signature and Analysis of Immune Cell Infiltration in Low‐Grade Gliomas","year":2021,"lang":"en","type":"article","venue":"BioMed Research International","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Autophagy; Glioma; Immune system; Oncology; Gene signature; Medicine; Gene; Internal medicine; Cancer research; Biology; Immunology; Apoptosis; Gene expression; Genetics","score_opus":0.022381735906452472,"score_gpt":0.36291566171295336,"score_spread":0.3405339258065009,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3214333524","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99611855,0.0023392898,0.000092966104,0.0005861991,0.00013445027,0.00024308926,0.00007057641,0.00000991703,0.00040499438],"genre_scores_gemma":[0.9982151,0.00031147944,0.00009335111,0.000010264013,0.000029865074,0.000022710823,0.00066416943,0.000007737163,0.00064534746],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99820817,0.00014687226,0.0005487478,0.00022207748,0.00073266943,0.00014147203],"domain_scores_gemma":[0.99869573,0.00019238799,0.00015353675,0.00020248412,0.0006896814,0.000066189816],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070175173,0.000071848866,0.00022611562,0.0014812758,0.00002575077,0.000018078206,0.00011469188,0.000114802366,0.000331285],"category_scores_gemma":[0.0004224394,0.000067048495,0.00010621954,0.002371289,0.00017248192,0.000090322545,0.00004813836,0.00020407814,0.0000036343954],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014166912,0.0008296893,0.026717179,0.00013015875,0.00078083907,0.00007714781,0.00042699004,0.00004912873,0.96853685,0.0012008304,0.000036969257,0.0010725232],"study_design_scores_gemma":[0.0009109003,0.00005765304,0.50658596,0.00007754165,0.00009809636,0.000004636554,0.00012543213,0.011751657,0.47979233,0.00051755353,0.00003888006,0.00003936021],"about_ca_topic_score_codex":0.00003402171,"about_ca_topic_score_gemma":0.000006900788,"teacher_disagreement_score":0.48874456,"about_ca_system_score_codex":0.000067300716,"about_ca_system_score_gemma":0.0002078351,"threshold_uncertainty_score":0.36273384},"labels":[],"label_agreement":null},{"id":"W3214721472","doi":"10.3390/cancers13225721","title":"Autophagy: The Potential Link between SARS-CoV-2 and Cancer","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"Silesian University of Technology","keywords":"Autophagy; Cancer; Coronavirus disease 2019 (COVID-19); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Colorectal cancer; Immune system; Immunology; Medicine; Biology; Disease; Apoptosis; Internal medicine; Genetics; Infectious disease (medical specialty)","score_opus":0.027228664389189774,"score_gpt":0.3251357881205182,"score_spread":0.29790712373132844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3214721472","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97261083,0.01895682,0.00008884169,0.0064012767,0.00038810325,0.00014850406,0.0000346382,0.000049185343,0.0013217872],"genre_scores_gemma":[0.98980755,0.0023351116,0.000050174902,0.0051601566,0.001528864,0.000031838055,0.000017026392,0.000019493427,0.0010497607],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993169,0.000026838758,0.00011484078,0.00020512164,0.00014974107,0.00018660046],"domain_scores_gemma":[0.9995647,0.000023691511,0.000036794943,0.00024233272,0.00006071217,0.00007175346],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005263609,0.00010287447,0.00018246491,0.000018978004,0.000104967214,0.000022036551,0.000060572394,0.00006400466,0.00021807863],"category_scores_gemma":[0.000014182185,0.00007248993,0.00007378341,0.0001268445,0.00011806123,0.000038617483,0.000030668874,0.00015473476,0.0000142435765],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035328112,0.000027710681,0.015654268,0.0002488399,0.0018603342,0.0011114565,0.0017925296,0.00011812551,0.24295022,0.00092502835,0.03106173,0.70389646],"study_design_scores_gemma":[0.0030725251,0.00010946833,0.13526471,0.00017410606,0.00069853984,0.00006280953,0.00028025516,0.0006603657,0.58087766,0.0012971559,0.27720982,0.00029255223],"about_ca_topic_score_codex":0.00026402433,"about_ca_topic_score_gemma":0.000021145072,"teacher_disagreement_score":0.7036039,"about_ca_system_score_codex":0.00021645548,"about_ca_system_score_gemma":0.0008569116,"threshold_uncertainty_score":0.29560533},"labels":[],"label_agreement":null},{"id":"W3215278354","doi":"10.1371/journal.pone.0260519","title":"Inhibition of histone deacetylation with vorinostat does not prevent tunicamycin-mediated acute kidney injury","year":2021,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McMaster University; St. Joseph’s Healthcare Hamilton","funders":"Kidney Foundation of Canada; McMaster University","keywords":"Vorinostat; Histone deacetylase; Unfolded protein response; Tunicamycin; Histone deacetylase inhibitor; Acute kidney injury; Cancer research; Pharmacology; Acetylation; Programmed cell death; Chemistry; Histone; Apoptosis; Medicine; Biochemistry; Internal medicine","score_opus":0.0186398456271817,"score_gpt":0.2745120392963631,"score_spread":0.2558721936691814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3215278354","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967813,0.00018037492,0.000060456656,0.0018236535,0.000033559863,0.0003560581,0.00020654153,0.000070644914,0.00048740653],"genre_scores_gemma":[0.99362636,0.00063462264,0.0017894926,0.0011782758,0.00009717765,0.00003436761,0.00076213985,0.000027253127,0.0018503438],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988715,0.000051246225,0.00026548048,0.00022580558,0.00043239063,0.00015358966],"domain_scores_gemma":[0.99902374,0.00003313067,0.0001379367,0.00034472064,0.00026301516,0.00019748072],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000072782765,0.00012643456,0.00032558767,0.00007151379,0.000036819634,0.000005799124,0.000035656307,0.000075593554,0.00043470258],"category_scores_gemma":[0.00010117101,0.00009393913,0.000058046673,0.00020682997,0.00006457821,0.00009773595,0.000027101025,0.00013351774,0.000029245342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010864695,0.0033668636,0.004520439,0.00027838306,0.0009588026,0.00011208595,0.00032678785,2.6166154e-7,0.988441,0.00012111779,0.00027222696,0.0005155813],"study_design_scores_gemma":[0.0018255223,0.00048683313,0.011521831,0.0007024209,0.0008252545,0.0000057236757,0.000028410012,0.000078746474,0.98417205,0.00011464322,0.000123124,0.00011545588],"about_ca_topic_score_codex":0.000010366239,"about_ca_topic_score_gemma":0.000002608665,"teacher_disagreement_score":0.0070013925,"about_ca_system_score_codex":0.00006823884,"about_ca_system_score_gemma":0.00028333464,"threshold_uncertainty_score":0.47596884},"labels":[],"label_agreement":null},{"id":"W3215638570","doi":"10.1242/jcs.258733","title":"Snazarus and its human ortholog SNX25 modulate autophagic flux","year":2021,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Autophagy; Flux (metallurgy); Cell biology; Computational biology; Genetics; Apoptosis","score_opus":0.017113544978374626,"score_gpt":0.3058496828771837,"score_spread":0.2887361378988091,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3215638570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989769,0.0038728246,0.000033627133,0.00045990033,0.00021085402,0.000045340454,8.1500826e-7,0.000008264608,0.005599376],"genre_scores_gemma":[0.99567115,0.00023095719,0.00041543646,0.00059877685,0.00013076732,3.5021014e-7,4.6297777e-7,0.000005757051,0.0029463118],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889475,0.000025457608,0.0002611024,0.00015827207,0.00045441135,0.00020602428],"domain_scores_gemma":[0.9990684,0.000020439085,0.00017357481,0.00014770229,0.0003082393,0.00028167156],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004843791,0.00008134581,0.0002100614,0.00011853902,0.00016303078,0.00004161696,0.0001425575,0.000036873484,0.00039249513],"category_scores_gemma":[0.00006583433,0.000060972994,0.00007524039,0.00032127276,0.0001720395,0.00023579242,0.000049466355,0.00018460996,0.000015516083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022761433,0.0001245376,0.0011349595,0.000019293713,0.000012453816,0.0014407884,0.00017639154,0.000014584291,0.9950563,0.0003779619,0.00014795472,0.0014720276],"study_design_scores_gemma":[0.0012583736,0.00032112724,0.14210224,0.0000697595,0.000061247185,0.0012883754,0.00007593938,0.0004038837,0.8518828,0.0011064115,0.0013383792,0.000091446105],"about_ca_topic_score_codex":5.9645936e-7,"about_ca_topic_score_gemma":2.914584e-7,"teacher_disagreement_score":0.14317347,"about_ca_system_score_codex":0.000037364098,"about_ca_system_score_gemma":0.0004386688,"threshold_uncertainty_score":0.42975464},"labels":[],"label_agreement":null},{"id":"W3216087103","doi":"10.1007/978-3-030-78799-8_6","title":"Cross Talk Between Apoptosis and Autophagy in Regulating the Progression of Heart Disease","year":2021,"lang":"en","type":"book-chapter","venue":"Advances in biochemistry in health and disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Autophagy; Cell biology; Programmed cell death; Apoptosis; Biology; Intracellular; Cardiac myocyte; Signal transduction; Myocyte; Genetics","score_opus":0.014661547189022376,"score_gpt":0.3522763176875381,"score_spread":0.33761477049851574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3216087103","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.69057995,0.30550846,0.0000015942411,0.0016777875,0.000053512733,0.00071965007,0.00019751911,0.000018233082,0.0012433007],"genre_scores_gemma":[0.9806521,0.014647694,0.00013819872,0.00095046125,0.00017661395,0.00008396465,0.00037212705,0.000038238133,0.0029406257],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9979531,0.00004579877,0.0007600358,0.00059025455,0.0003044862,0.00034631637],"domain_scores_gemma":[0.9980845,0.00018134383,0.00029139026,0.00045327962,0.00004567208,0.0009438014],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024038063,0.00031565683,0.00063856784,0.00010174878,0.00007596189,0.000017924322,0.000093792216,0.00016331823,0.000049877242],"category_scores_gemma":[0.000294047,0.00025714762,0.000087539374,0.00010473632,0.00040612597,0.00009108494,0.00010260086,0.0003886577,3.2110972e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004370632,0.0005540698,0.87677366,0.03264265,0.00005323031,0.0004835244,0.00035936738,0.00004530283,0.00033673874,0.0022125025,0.000083029765,0.082085274],"study_design_scores_gemma":[0.01984247,0.00092630705,0.77839094,0.08469739,0.00040826434,0.000048944927,0.0007676792,0.0006290157,0.01190152,0.0628584,0.036800753,0.002728334],"about_ca_topic_score_codex":0.000023063529,"about_ca_topic_score_gemma":0.0000030864383,"teacher_disagreement_score":0.29086077,"about_ca_system_score_codex":0.00008252453,"about_ca_system_score_gemma":0.00092679955,"threshold_uncertainty_score":0.9999881},"labels":[],"label_agreement":null},{"id":"W3217304570","doi":"10.21203/rs.3.rs-1104184/v1","title":"The Influence of Age, Sex and Exercise on Autophagy, Mitophagy and Lysosome Biogenesis in Skeletal Muscle","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"TFEB; Mitophagy; Autophagy; Lysosome; Sarcopenia; Skeletal muscle; Biology; Endocrinology; Biogenesis; Mitochondrion; Mitochondrial biogenesis; Internal medicine; Cell biology; Protein turnover; Medicine; Protein biosynthesis; Gene; Biochemistry; Enzyme; Apoptosis","score_opus":0.0323869892151831,"score_gpt":0.36788797263210066,"score_spread":0.3355009834169176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3217304570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96876454,0.02944878,7.3037205e-7,0.00036964653,0.000052225365,0.0010738919,0.00005575537,0.000025624462,0.00020881102],"genre_scores_gemma":[0.97043085,0.028607557,0.00005005834,0.00005129065,0.000088215646,0.00019811648,0.000049419763,0.00003845987,0.00048604675],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99710757,0.00038682876,0.0003992817,0.0006583439,0.00093511766,0.0005128456],"domain_scores_gemma":[0.99781555,0.0006178973,0.00008883282,0.00091193285,0.00029034854,0.00027544182],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010401026,0.00026525656,0.000589359,0.0004058217,0.00017794257,0.000106885964,0.0002596791,0.0003191747,0.000043287317],"category_scores_gemma":[0.00036132036,0.00019644253,0.0001365478,0.00043729963,0.0006508707,0.00005606346,0.0007388588,0.0009604988,0.00000533889],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028210313,0.0051546707,0.14557217,0.02652041,0.0015682627,0.015384707,0.01566877,0.0010617529,0.10473603,0.0020442912,0.0010596949,0.6784082],"study_design_scores_gemma":[0.0012426788,0.00038140026,0.97800803,0.0030723729,0.000039151302,0.0000117653335,0.001054083,0.00015646227,0.014062542,0.0011433732,0.0006214338,0.0002067159],"about_ca_topic_score_codex":0.00055798364,"about_ca_topic_score_gemma":0.00005532646,"teacher_disagreement_score":0.83243585,"about_ca_system_score_codex":0.0000924527,"about_ca_system_score_gemma":0.00045347644,"threshold_uncertainty_score":0.8010694},"labels":[],"label_agreement":null},{"id":"W348308627","doi":"10.1096/fasebj.26.1_supplement.1060.15","title":"Transfat‐mediated apoptosis is regulated by autophagy in primary cardiac myofibroblasts","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Data Fusion Corporation","keywords":"Autophagy; ATG5; Apoptosis; Programmed cell death; Chemistry; Autophagosome; Cell biology; Lysosome; Caspase; Caspase 8; Biochemistry; Biology","score_opus":0.009431474618940415,"score_gpt":0.2401661517698501,"score_spread":0.23073467715090967,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W348308627","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98940367,0.006486134,0.00006676663,0.0015881167,0.00042123173,0.00028590727,0.00004935302,0.00005564965,0.0016431947],"genre_scores_gemma":[0.9947205,0.0010511405,0.00006875995,0.0024792545,0.00049858243,0.000011717117,0.00005333663,0.0000428548,0.0010738529],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981689,0.00020530677,0.00041795787,0.00015003522,0.00045977984,0.0005980171],"domain_scores_gemma":[0.99898165,0.00009992196,0.00012173169,0.00031341796,0.000056152352,0.00042714467],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006299524,0.00022396744,0.0004139508,0.00013299631,0.00015715504,0.00002949505,0.00018151765,0.0001448941,0.00093877147],"category_scores_gemma":[0.000023027822,0.00014739088,0.00026338565,0.00034631795,0.00010832692,0.00022730818,0.000020098958,0.0005789665,0.00013332494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007659824,0.00049752597,0.01486556,0.000041615585,0.00049693167,0.000022922824,0.0028661648,0.0000047141743,0.94440573,0.000026728198,0.029035352,0.0069707683],"study_design_scores_gemma":[0.003981754,0.00024011264,0.1559708,0.00019454236,0.00029215458,0.00018043372,0.00024155303,0.00006443987,0.8319629,0.00013112808,0.006455486,0.00028469652],"about_ca_topic_score_codex":0.000017209988,"about_ca_topic_score_gemma":2.0490572e-7,"teacher_disagreement_score":0.14110523,"about_ca_system_score_codex":0.00017678436,"about_ca_system_score_gemma":0.00015431207,"threshold_uncertainty_score":0.9999745},"labels":[],"label_agreement":null},{"id":"W348749725","doi":"10.1007/978-1-4419-9530-8_7","title":"Caspase-Independent Stroke Targets","year":2012,"lang":"en","type":"book-chapter","venue":"Translational Stroke Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autophagy; Mitophagy; Cell biology; Programmed cell death; Caspase; PINK1; Apoptosis; Biology; Mitochondrion; Apoptosis-inducing factor; Effector; Neuroscience; Genetics","score_opus":0.10661971590884067,"score_gpt":0.3829441540083066,"score_spread":0.27632443809946594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W348749725","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002003215,0.036727235,0.00025159845,0.0015809198,0.00023222742,0.0014062067,0.0014834513,0.000112150396,0.956203],"genre_scores_gemma":[0.28564253,0.0020167716,0.00029249198,0.000113650174,0.0017887873,0.000053972624,0.00085883256,0.00013694535,0.709096],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99494076,0.00007420768,0.00046521926,0.00054405734,0.003166314,0.00080944196],"domain_scores_gemma":[0.9978869,0.00030827968,0.00008417162,0.00054845936,0.000510527,0.00066165806],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00087113475,0.00039917944,0.00056022976,0.0005694077,0.00026633206,0.000036413745,0.00025039646,0.0006147998,0.022744654],"category_scores_gemma":[0.000019766201,0.00036943774,0.00048402057,0.0000552154,0.0002975598,0.00011454103,0.00004442786,0.0018333525,0.0021391644],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005622717,0.0014691759,0.00409995,0.0012711568,0.005919071,0.002223216,0.0010077595,0.000036610858,0.011231123,0.76812756,0.022370992,0.17662066],"study_design_scores_gemma":[0.004019982,0.0005576211,0.013882014,0.000374775,0.000415218,0.00014466736,0.000028948098,0.00008187501,0.0027885514,0.020581735,0.9563925,0.00073208864],"about_ca_topic_score_codex":0.000035509493,"about_ca_topic_score_gemma":0.000019206378,"teacher_disagreement_score":0.93402153,"about_ca_system_score_codex":0.00020544825,"about_ca_system_score_gemma":0.0007634125,"threshold_uncertainty_score":0.9998758},"labels":[],"label_agreement":null},{"id":"W37685847","doi":"10.3390/ijms241713040","title":"Пензенский филиал Международного независимого эколого-политологического университета как фактор формирования экологической культуры в регионе","year":2005,"lang":"en","type":"article","venue":"Успехи современного естествознания","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Ecology; Environmental education; Subject (documents); Sociology; Comprehension; Environmental ethics; Pedagogy; Computer science","score_opus":0.009362156139172273,"score_gpt":0.29377749975492357,"score_spread":0.28441534361575127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W37685847","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8127992,0.013203755,0.0020378993,0.015049282,0.003565679,0.00394779,0.00031870385,0.0035126396,0.14556505],"genre_scores_gemma":[0.93675387,0.001627934,0.0044925027,0.012467697,0.0068781245,0.00042480446,0.00047167038,0.00061945774,0.036263965],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9884678,0.0004323181,0.0025407888,0.0027082753,0.0026177145,0.0032331054],"domain_scores_gemma":[0.9916449,0.00044015519,0.00087174657,0.003817838,0.0008196736,0.0024056726],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.0012314812,0.002097187,0.0025350358,0.0011933404,0.0009697517,0.00035478955,0.0016365905,0.0013055638,0.016056085],"category_scores_gemma":[0.00048196348,0.001963319,0.0017759107,0.0019931651,0.00087720586,0.0012032535,0.00060022017,0.0021849272,0.010298134],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00729836,0.013886707,0.02579174,0.0016941881,0.0051070726,0.0040016854,0.0048715333,0.0007503289,0.07790542,0.02253337,0.31573147,0.5204281],"study_design_scores_gemma":[0.019757096,0.002229226,0.0918886,0.0012661164,0.001967655,0.0019229229,0.0008953917,0.0036294905,0.06904209,0.0044881394,0.7981882,0.0047250707],"about_ca_topic_score_codex":0.00016086668,"about_ca_topic_score_gemma":0.00014794269,"teacher_disagreement_score":0.515703,"about_ca_system_score_codex":0.0009182167,"about_ca_system_score_gemma":0.0013353011,"threshold_uncertainty_score":0.99999094},"labels":[],"label_agreement":null},{"id":"W4200002977","doi":"10.3390/cancers13236124","title":"Induction of Apoptosis in Human Pancreatic Cancer Stem Cells by the Endoplasmic Reticulum-Targeted Alkylphospholipid Analog Edelfosine and Potentiation by Autophagy Inhibition","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministerio de Ciencia e Innovación; China Scholarship Council; CNIB","keywords":"Pancreatic cancer; Endoplasmic reticulum; Autophagy; Cancer research; Apoptosis; Cancer cell; Cancer stem cell; Biology; Cancer; Cell biology; Chemistry; Internal medicine; Stem cell; Medicine; Biochemistry","score_opus":0.009405966664418643,"score_gpt":0.2478416554842032,"score_spread":0.23843568881978455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200002977","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9884075,0.010146901,0.00004525659,0.00061859994,0.00021702332,0.00031236236,0.00009584557,0.000023341127,0.00013316238],"genre_scores_gemma":[0.9956731,0.002960396,0.000013640534,0.0004889291,0.00006785093,0.00008446476,0.00017907663,0.000019764686,0.00051278074],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99897,0.00006964167,0.00030374233,0.00026867018,0.00020249453,0.00018548855],"domain_scores_gemma":[0.999444,0.000022702698,0.00016611292,0.0001973735,0.00009552687,0.000074290256],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009892672,0.00014091305,0.00027668127,0.00006118218,0.000082197614,0.000013736872,0.000036741705,0.00009848472,0.00020358726],"category_scores_gemma":[0.000007563158,0.000118298914,0.000057473986,0.00034979172,0.00012653472,0.00009385208,0.0000151990225,0.00015227427,0.0000011030678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009204654,0.00005340413,0.0015040162,0.00010649296,0.000114657996,0.0000051341485,0.00038724183,0.00015311444,0.9875238,0.00006583277,0.0067529087,0.0032413842],"study_design_scores_gemma":[0.0016922333,0.00009701286,0.0047384584,0.00019370689,0.00017683108,0.000006778337,0.00041730618,0.00046083008,0.99133223,0.000073271,0.0007021653,0.00010916766],"about_ca_topic_score_codex":0.0012990637,"about_ca_topic_score_gemma":0.00007590881,"teacher_disagreement_score":0.0072655887,"about_ca_system_score_codex":0.00047847428,"about_ca_system_score_gemma":0.00025731674,"threshold_uncertainty_score":0.482409},"labels":[],"label_agreement":null},{"id":"W4200161338","doi":"10.1016/j.jare.2021.12.009","title":"Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux","year":2021,"lang":"en","type":"article","venue":"Journal of Advanced Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Natural Science Foundation of Hunan Province; National Natural Science Foundation of China","keywords":"Autophagy; Senescence; Metformin; Vascular smooth muscle; Autophagosome; Cell biology; Biology; Endocrinology; Internal medicine; Chemistry; Medicine; Apoptosis; Biochemistry; Diabetes mellitus","score_opus":0.02703982862964504,"score_gpt":0.35964290554540973,"score_spread":0.3326030769157647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200161338","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9622195,0.033356648,0.0007329977,0.0007157274,0.00017951423,0.0002707828,0.000007975774,0.000022314489,0.002494536],"genre_scores_gemma":[0.9877315,0.004138779,0.00404096,0.00015976917,0.00031836904,0.000008871628,0.000012947698,0.000044060078,0.00354471],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99694556,0.00036557196,0.0005189952,0.00025699643,0.0013777568,0.0005350899],"domain_scores_gemma":[0.9974274,0.00033072577,0.00019287225,0.00039375306,0.0012287417,0.00042651876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018381128,0.00014979129,0.00043147634,0.00020104136,0.00018226239,0.00005350149,0.0002493435,0.000094578565,0.0006294692],"category_scores_gemma":[0.0007799195,0.000117513744,0.00025772667,0.00058164936,0.0001207998,0.00034376438,0.00009281524,0.0009542923,0.00003160739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001497839,0.0006589195,0.00015136859,0.00026779255,0.000086660664,0.0016785435,0.00035516822,0.00003930379,0.9307822,0.000018414474,0.0039414335,0.061870422],"study_design_scores_gemma":[0.002569142,0.0006941144,0.002546631,0.00038399687,0.000054834043,0.00017990384,0.0010017974,0.00022388066,0.9090417,0.000570646,0.08260799,0.00012534953],"about_ca_topic_score_codex":0.0000038135588,"about_ca_topic_score_gemma":7.477757e-7,"teacher_disagreement_score":0.07866655,"about_ca_system_score_codex":0.00013049714,"about_ca_system_score_gemma":0.0007733216,"threshold_uncertainty_score":0.68922466},"labels":[],"label_agreement":null},{"id":"W4200191856","doi":"10.1016/j.neo.2021.12.003","title":"MLH1 mediates cytoprotective nucleophagy to resist 5-Fluorouracil-induced cell death in colorectal carcinoma","year":2021,"lang":"en","type":"article","venue":"Neoplasia","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"University of Sharjah","keywords":"MLH1; Biology; Cancer research; Microsatellite instability; Gene knockdown; DNA repair; Cell biology; DNA mismatch repair; Cell culture; Genetics; Gene","score_opus":0.014469053512801132,"score_gpt":0.26506680113932063,"score_spread":0.2505977476265195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200191856","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9875788,0.0006148609,0.000011143818,0.00065361714,0.00023799864,0.0005935583,0.000027016576,0.0000913505,0.010191636],"genre_scores_gemma":[0.99730915,0.000027376598,0.00053200393,0.0009571217,0.00025384955,0.0001242153,0.00003955454,0.000048015656,0.00070868933],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983073,0.00010548692,0.0002991103,0.0005131514,0.0003357338,0.000439255],"domain_scores_gemma":[0.99897164,0.00011868931,0.00006186782,0.0003533807,0.00014606974,0.0003483229],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000106121035,0.00024691122,0.0004564055,0.00016176872,0.00008716052,0.000028688284,0.00012344461,0.00018535399,0.00053792866],"category_scores_gemma":[0.00015616266,0.00023921866,0.00013078848,0.000510132,0.000025249989,0.00007943697,0.00007233754,0.00033150605,0.00036193398],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002391327,0.0011427283,0.20355304,0.00016523794,0.0001388809,0.008995821,0.00451964,0.000010528703,0.77009493,0.00045632134,0.0012170548,0.007314489],"study_design_scores_gemma":[0.0019582708,0.00039207115,0.52023923,0.000040754345,0.000043603464,0.0000824956,0.0003713175,0.00004368861,0.4760948,0.00020369353,0.00037169998,0.00015836136],"about_ca_topic_score_codex":0.00019292916,"about_ca_topic_score_gemma":0.00020980618,"teacher_disagreement_score":0.3166862,"about_ca_system_score_codex":0.00022900602,"about_ca_system_score_gemma":0.00046622538,"threshold_uncertainty_score":0.9755054},"labels":[],"label_agreement":null},{"id":"W4200271175","doi":"10.1016/j.semcdb.2021.11.026","title":"Emerging role of mitophagy in myoblast differentiation and skeletal muscle remodeling","year":2021,"lang":"en","type":"review","venue":"Seminars in Cell and Developmental Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mitophagy; Myogenesis; Skeletal muscle; Cell biology; Mitochondrion; Myocyte; Biology; Bioenergetics; Autophagy; Anatomy; Biochemistry","score_opus":0.013941692539871821,"score_gpt":0.29171103072125015,"score_spread":0.27776933818137833,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200271175","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23362893,0.76576966,0.000003546217,0.000003223693,0.00006118579,0.00019425029,0.000009105508,0.000005170012,0.00032490978],"genre_scores_gemma":[0.044114083,0.954738,0.0006898689,0.000022381528,0.000028113258,0.000022832171,0.00029101572,0.00001731505,0.00007635693],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99877733,0.00008141221,0.000517106,0.00036215922,0.000060783503,0.00020121822],"domain_scores_gemma":[0.9996131,0.00009597225,0.00013218384,0.00008565898,0.000014705299,0.000058367732],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012483397,0.00022803003,0.0009923292,0.00025020546,0.0000251483,0.000004478677,0.000049743423,0.00027343165,0.000051887633],"category_scores_gemma":[0.000019575386,0.00019490784,0.000082101666,0.00018031237,0.00007008425,0.00002436605,0.00011095655,0.00021690651,0.0000018361478],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009804048,0.000102628066,0.0019775615,0.0024117352,0.000035654164,0.000031191485,0.00046482732,1.0533885e-7,0.0015108051,0.000019955505,0.0000055820283,0.99343014],"study_design_scores_gemma":[0.007835346,0.0008320415,0.016886393,0.09348828,0.00088037224,0.0007868237,0.00882379,0.0004173756,0.009656932,0.0017115806,0.85611904,0.00256205],"about_ca_topic_score_codex":0.000021548076,"about_ca_topic_score_gemma":0.000011355093,"teacher_disagreement_score":0.9908681,"about_ca_system_score_codex":0.00007085775,"about_ca_system_score_gemma":0.00016772529,"threshold_uncertainty_score":0.7948111},"labels":[],"label_agreement":null},{"id":"W4200308570","doi":"10.1101/2021.12.13.472440","title":"PIKfyve inhibition reveals a novel role for Inpp4b in the regulation of PtdIns(3)P and lysosome dynamics","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network; Toronto Metropolitan University; Université de Montréal; Montreal Clinical Research Institute","funders":"Temerty Faculty of Medicine, University of Toronto; University of Toronto; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Lysosome; Cell biology; Endocytic cycle; Crosstalk; Autophagy; Endosome; Autophagosome; Biology; Mannose 6-phosphate receptor; Biochemistry; Cell; Endocytosis; Intracellular; Enzyme","score_opus":0.01355938349190728,"score_gpt":0.24007140635702887,"score_spread":0.2265120228651216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200308570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99407184,0.0017480144,0.0018070875,0.00045836475,0.0001610222,0.0014276893,0.00026408886,0.000053029933,0.000008887075],"genre_scores_gemma":[0.99579954,0.00025902624,0.0029556414,0.00040069644,0.00021486483,0.00029848499,0.000007639035,0.000060424027,0.000003690574],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99830174,0.00008041275,0.0005340104,0.0005287112,0.0003025833,0.00025251528],"domain_scores_gemma":[0.9982668,0.00010600278,0.0003745259,0.00076213025,0.0003937724,0.00009678172],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00063826947,0.0002932486,0.00055503135,0.00022859435,0.00006355756,0.0000624216,0.0001310615,0.00039664752,0.000011890042],"category_scores_gemma":[0.00020544099,0.00026185525,0.00014705448,0.0003737941,0.00009739267,0.00010661816,0.00011210448,0.00036159882,8.9934457e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018573937,0.0004395656,0.008668625,0.0012172408,0.0001480704,0.000017177117,0.00009977126,0.000029109959,0.98503643,0.004119963,0.000029821747,0.000008489206],"study_design_scores_gemma":[0.0027335198,0.00015603376,0.82463676,0.001662085,0.000357262,1.4716888e-7,0.00007449739,0.004453805,0.1652713,0.000108465276,0.00013178219,0.00041434946],"about_ca_topic_score_codex":0.000032896096,"about_ca_topic_score_gemma":0.00000702672,"teacher_disagreement_score":0.81976515,"about_ca_system_score_codex":0.00018811559,"about_ca_system_score_gemma":0.000367282,"threshold_uncertainty_score":0.9999834},"labels":[],"label_agreement":null},{"id":"W4200387780","doi":"10.1016/j.bbadis.2021.166326","title":"Targeted regulation of autophagy using nanoparticles: New insight into cancer therapy","year":2021,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"","keywords":"Autophagy; Nanocarriers; ATG5; Cancer cell; Cancer; Cell biology; Cancer research; Chemistry; Apoptosis; Biology; Nanotechnology; Materials science; Nanoparticle; Biochemistry","score_opus":0.041263390621707,"score_gpt":0.35351931674203624,"score_spread":0.31225592612032926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200387780","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.32796726,0.6704933,0.00003369397,0.00018872584,0.00012026336,0.0009462395,0.00018056856,0.000050300412,0.000019658293],"genre_scores_gemma":[0.17766212,0.8199523,0.0007379002,0.00035567573,0.000208041,0.00008353018,0.00076244003,0.0001798625,0.000058105376],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962045,0.00045374842,0.0012136485,0.0009062321,0.0008034889,0.000418389],"domain_scores_gemma":[0.9963196,0.00008169728,0.0011454135,0.0014410785,0.00031828726,0.0006939517],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001192479,0.000812559,0.002539478,0.00038748584,0.000075259086,0.00003738167,0.00041559097,0.0003432618,0.00026017387],"category_scores_gemma":[0.000100667196,0.00070012885,0.0019342278,0.0011345334,0.00025890878,0.00014402297,0.00014665475,0.0002849756,0.0000063552943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053843175,0.0014988895,0.0000015336149,0.008261327,0.0029231904,0.000079436824,0.00029899512,0.000010889111,0.8723996,0.00026488313,0.0002427465,0.113480054],"study_design_scores_gemma":[0.0018000741,0.00024336459,0.00043329282,0.013680809,0.005886523,0.000004164842,0.00001452285,0.00009023156,0.95874196,0.00020052379,0.01815968,0.00074486306],"about_ca_topic_score_codex":0.00013724998,"about_ca_topic_score_gemma":9.30102e-7,"teacher_disagreement_score":0.15030514,"about_ca_system_score_codex":0.00017099107,"about_ca_system_score_gemma":0.003979072,"threshold_uncertainty_score":0.999545},"labels":[],"label_agreement":null},{"id":"W4200466215","doi":"10.1016/j.jbc.2021.101540","title":"p53 regulates skeletal muscle mitophagy and mitochondrial quality control following denervation-induced muscle disuse","year":2021,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Mitophagy; Denervation; Skeletal muscle; Cell biology; Mitochondrion; Biology; Chemistry; Internal medicine; Endocrinology; Autophagy; Medicine; Biochemistry; Apoptosis","score_opus":0.02981351481527975,"score_gpt":0.3061825794061014,"score_spread":0.2763690645908216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200466215","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954028,0.003052814,0.00008019397,0.0009357299,0.00027160614,0.00006818256,0.000008663466,0.000019186517,0.00016078568],"genre_scores_gemma":[0.9976199,0.00017081894,0.0004872792,0.00047516383,0.0010798223,0.0000031660234,0.000018578346,0.0000099299505,0.00013533646],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986802,0.000088089124,0.0005543075,0.00021942247,0.0002542287,0.00020376036],"domain_scores_gemma":[0.998818,0.00026993206,0.00027968892,0.0001884756,0.0001847744,0.00025913896],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022991664,0.0001590262,0.0005049447,0.000016152868,0.00007831952,0.000022547427,0.00009221792,0.00024121272,0.00025008147],"category_scores_gemma":[0.0009108985,0.00011127293,0.00040654276,0.00010233823,0.00007629486,0.000079888276,0.00003277438,0.00029928237,0.00000198296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019193535,0.00025179237,0.00614469,0.000038412258,0.00020418057,0.00053605286,0.000029202878,0.0000010303349,0.98903173,0.000011176035,0.000111585796,0.0034481958],"study_design_scores_gemma":[0.0059160194,0.00020950328,0.3381942,0.00011339958,0.00014721057,0.00021795699,0.00019372808,0.000023490893,0.6528931,0.00073585316,0.001172183,0.0001833209],"about_ca_topic_score_codex":0.0000028556947,"about_ca_topic_score_gemma":3.11317e-7,"teacher_disagreement_score":0.3361386,"about_ca_system_score_codex":0.00004450959,"about_ca_system_score_gemma":0.00013623206,"threshold_uncertainty_score":0.45375785},"labels":[],"label_agreement":null},{"id":"W4205210641","doi":"10.1098/rsob.210255","title":"Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria","year":2022,"lang":"en","type":"article","venue":"Open Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"Institute of Neurosciences, Mental Health and Addiction; Canadian Institutes of Health Research; Canada Research Chairs; Canada Foundation for Innovation","keywords":"Parkin; Mitophagy; PINK1; Ubiquitin; Ubiquitin ligase; MFN2; Biology; Mitochondrion; Cell biology; Biochemistry; Autophagy; mitochondrial fusion; Mitochondrial DNA; Parkinson's disease","score_opus":0.021262265503017602,"score_gpt":0.3203782330783434,"score_spread":0.29911596757532577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205210641","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98394734,0.00076641585,0.0013347815,0.00061785267,0.00044186137,0.0015846592,0.00025898658,0.00004147758,0.011006621],"genre_scores_gemma":[0.99676996,0.000048406793,0.000050316223,0.00077950547,0.00005449238,0.00014817648,0.000981148,0.000012685552,0.001155297],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916387,0.00021273915,0.00017511798,0.00021955906,0.000095792595,0.00013294314],"domain_scores_gemma":[0.99958843,0.0000389836,0.00011947226,0.00013608031,0.00007646759,0.000040552524],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000116033865,0.00008435255,0.00020148404,0.00004577501,0.00014790359,0.000010116877,0.00015220529,0.00006387673,0.0020363124],"category_scores_gemma":[0.000042110507,0.00007528727,0.000036409325,0.00015884113,0.000043648597,0.00004294948,0.000102616475,0.00010544772,0.000017482724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0111130215,0.003996801,0.011436166,0.000165194,0.0011008062,0.000017869566,0.002285567,0.00071759487,0.77580243,0.03177116,0.13109334,0.03050006],"study_design_scores_gemma":[0.005659934,0.005477033,0.0062086256,0.00004863697,0.00013449808,0.000012124223,0.00023132259,0.0028588423,0.6799168,0.0033332887,0.29584175,0.0002771706],"about_ca_topic_score_codex":0.000073868694,"about_ca_topic_score_gemma":0.000004510048,"teacher_disagreement_score":0.1647484,"about_ca_system_score_codex":0.000060902184,"about_ca_system_score_gemma":0.000116976065,"threshold_uncertainty_score":0.998876},"labels":[],"label_agreement":null},{"id":"W4205461697","doi":"10.1016/j.bbadis.2022.166354","title":"Intersection of autophagy regulation and circadian rhythms in the heart","year":2022,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; Biology; Homeostasis; Circadian rhythm; Programmed cell death; Neuroscience; Mechanism (biology); ULK1; Biochemistry; Apoptosis; AMPK","score_opus":0.027005277356958315,"score_gpt":0.3184268076899745,"score_spread":0.2914215303330162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205461697","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.42551112,0.57201076,0.000007783705,0.00048953417,0.00010273965,0.0014600926,0.00022896587,0.000030558323,0.00015846886],"genre_scores_gemma":[0.5328416,0.4658863,0.00004098707,0.00037029502,0.00006711643,0.00017066438,0.0005458616,0.000062723375,0.0000144020305],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973068,0.00059193507,0.0007354921,0.0005671961,0.0005466494,0.00025188286],"domain_scores_gemma":[0.9981186,0.00014687532,0.0005322612,0.00093986484,0.000047179936,0.00021525951],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028710745,0.00043965506,0.0012617832,0.00045059875,0.00006196602,0.000022289012,0.00027420235,0.00016200273,0.000103513354],"category_scores_gemma":[0.00010006224,0.0003477961,0.00081799994,0.00069368276,0.00022505019,0.000080296115,0.00011448852,0.00038016858,0.000003482667],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005300305,0.015721865,0.000030375368,0.12053553,0.0071567125,0.0009993791,0.004317584,0.000015372736,0.16873743,0.010647161,0.002615102,0.6639232],"study_design_scores_gemma":[0.019356644,0.008496013,0.09104497,0.06626706,0.04851241,0.00053932506,0.0015316948,0.00062602863,0.24196626,0.0069205915,0.5075698,0.0071691996],"about_ca_topic_score_codex":0.000034172434,"about_ca_topic_score_gemma":9.111535e-7,"teacher_disagreement_score":0.65675396,"about_ca_system_score_codex":0.00010111672,"about_ca_system_score_gemma":0.00053621404,"threshold_uncertainty_score":0.9998974},"labels":[],"label_agreement":null},{"id":"W4205894217","doi":"10.1111/jfd.13578","title":"Autophagy modulation in rainbow trout <i>Oncorhynchus mykiss</i> L. and resistance to experimental infection with <i>Flavobacterium psychrophilum</i>","year":2022,"lang":"en","type":"article","venue":"Journal of Fish Diseases","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Ontario Veterinary College, University of Guelph; Ontario Ministry of Agriculture, Food and Rural Affairs","keywords":"Biology; Rainbow trout; BECN1; Autophagy; Spleen; ATG12; Microbiology; Western blot; Andrology; Animal science; Internal medicine; Fish <Actinopterygii>; Fishery; Immunology; Gene; Biochemistry; Apoptosis; ATG5","score_opus":0.008132559798732007,"score_gpt":0.2628422615824523,"score_spread":0.25470970178372027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205894217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966013,0.0012491458,0.000029501576,0.0014402418,0.00012341142,0.00029496217,0.00003956343,0.000021262542,0.0002006155],"genre_scores_gemma":[0.99601436,0.0000848215,0.00016830604,0.0032220772,0.0002609167,0.000040294115,0.000012542245,0.00002359883,0.00017308358],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998763,0.00010246164,0.00035147354,0.00018472198,0.00042397928,0.00017436077],"domain_scores_gemma":[0.99923664,0.000029391987,0.00022308482,0.00015395245,0.00007688156,0.0002800603],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012597874,0.00014559164,0.00030711677,0.00022650613,0.000118806965,0.000029334977,0.00006488686,0.00002603952,0.00016178649],"category_scores_gemma":[0.000026289052,0.00012743688,0.000095329626,0.0002979186,0.00004294776,0.00022854835,0.000030851737,0.00018474286,9.131173e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.049297765,0.008114597,0.70315325,0.0004098191,0.0006516416,0.004110781,0.0030045954,0.0024868448,0.17724977,0.00025884528,0.042981055,0.008281037],"study_design_scores_gemma":[0.005379232,0.0021028796,0.97493565,0.00018029283,0.0001183156,0.00030085683,0.00027650574,0.00006573092,0.008219118,0.00016611027,0.0080581745,0.00019711298],"about_ca_topic_score_codex":0.000014542159,"about_ca_topic_score_gemma":0.000012566384,"teacher_disagreement_score":0.27178243,"about_ca_system_score_codex":0.00022016646,"about_ca_system_score_gemma":0.0001412242,"threshold_uncertainty_score":0.5196725},"labels":[],"label_agreement":null},{"id":"W4206465892","doi":"10.1080/15548627.2021.2021494","title":"Caffeine prevents restenosis and inhibits vascular smooth muscle cell proliferation through the induction of autophagy","year":2022,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; EU-CARDIOPROTECTION; National Medical Research Council; National Research Foundation Singapore; Ministry of Education - Singapore; National Research Foundation; BC Children’s Hospital Foundation; BC Children's Hospital; Children's Hospital Foundation","keywords":"Autophagy; Vascular smooth muscle; Wnt signaling pathway; Cell biology; Biology; Caffeine; AXIN2; Cell growth; ATG5; LRP5; Signal transduction; Cancer research; Pharmacology; Endocrinology; Biochemistry; Apoptosis","score_opus":0.014475534386587415,"score_gpt":0.2539726069995411,"score_spread":0.2394970726129537,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206465892","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928426,0.004302008,0.00012286536,0.0005669895,0.00026410745,0.00092826213,0.000021079439,0.00007918315,0.00087291],"genre_scores_gemma":[0.9970949,0.00028388327,0.00020834849,0.00089776015,0.00015817427,0.00021492614,0.000052898427,0.000037830265,0.0010512205],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982727,0.00022425456,0.00037600743,0.00035099185,0.0005339927,0.00024205298],"domain_scores_gemma":[0.99910694,0.000051036164,0.00020411651,0.0004881841,0.00007143064,0.00007826136],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032161677,0.00018927382,0.00030834824,0.00009057734,0.00036153005,0.000016996966,0.000136384,0.000077624754,0.00044657683],"category_scores_gemma":[0.000031470747,0.00014712539,0.00013437243,0.00038102586,0.000106280015,0.00017191638,0.00014071113,0.00028604202,0.0000070950405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016338227,0.0075346106,0.0050868313,0.0015503673,0.001399351,0.00029647283,0.035943426,0.0020951396,0.8079495,0.00899847,0.009392887,0.11811912],"study_design_scores_gemma":[0.009318204,0.0027304492,0.37149316,0.000121576966,0.0008569348,0.000094875664,0.0018362325,0.0018271146,0.5520016,0.005281818,0.0538467,0.00059135555],"about_ca_topic_score_codex":0.00015019637,"about_ca_topic_score_gemma":0.0000028748195,"teacher_disagreement_score":0.36640632,"about_ca_system_score_codex":0.00008086588,"about_ca_system_score_gemma":0.00014667449,"threshold_uncertainty_score":0.5999599},"labels":[],"label_agreement":null},{"id":"W4206534262","doi":"10.1101/2022.01.13.476189","title":"Dissecting the interactions of PINK1 with the TOM complex in depolarized mitochondria","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Deutsche Forschungsgemeinschaft","keywords":"PINK1; Mitophagy; Mitochondrion; Cell biology; Organelle; Chemistry; Biology; Autophagy; Biochemistry","score_opus":0.0200878284001285,"score_gpt":0.26564836214802084,"score_spread":0.24556053374789236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206534262","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950787,0.0009430621,0.00026184946,0.0014530141,0.0006803564,0.001317938,0.000094489114,0.00012065157,0.00004997996],"genre_scores_gemma":[0.997809,0.00007199793,0.0007521613,0.00049332017,0.00032094162,0.00044110944,0.0000010437229,0.00008810078,0.000022303846],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980242,0.00021100728,0.00047408824,0.0005132439,0.0004404094,0.00033705117],"domain_scores_gemma":[0.9974927,0.0002556927,0.00046397804,0.0014058625,0.0002691409,0.00011268333],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035786716,0.00035752347,0.00054898206,0.0001826653,0.000270887,0.00006539607,0.0005288981,0.00012808884,0.00034765527],"category_scores_gemma":[0.00015540313,0.00022158115,0.00019217546,0.0006559429,0.00019250887,0.000065377506,0.00035361885,0.0014331596,0.000006319136],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010323189,0.0007530955,0.07489463,0.00051640073,0.0011572124,0.00020205637,0.00025871297,0.00025348598,0.919123,0.0011810815,0.0006238046,0.0000042006523],"study_design_scores_gemma":[0.002665934,0.00020551884,0.9109404,0.00072420854,0.0006531931,2.5954893e-7,0.00035627227,0.00087062485,0.07252624,0.000008036502,0.010449277,0.0006000224],"about_ca_topic_score_codex":0.00026733716,"about_ca_topic_score_gemma":0.00003544891,"teacher_disagreement_score":0.8465968,"about_ca_system_score_codex":0.00021112736,"about_ca_system_score_gemma":0.0005144674,"threshold_uncertainty_score":0.90358174},"labels":[],"label_agreement":null},{"id":"W4206672430","doi":"10.1007/s12640-021-00396-0","title":"Regulation of Neurodegeneration-associated Protein Fragments by the N-degron Pathways","year":2022,"lang":"en","type":"review","venue":"Neurotoxicity Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Montreal Neurological Institute and Hospital","funders":"","keywords":"Degron; Neurodegeneration; Proteasome; Cell biology; Ubiquitin; Aggresome; Biology; Protein degradation; Protein aggregation; Neuroscience; Ubiquitin ligase; Chemistry; Biochemistry; Disease; Medicine; Gene","score_opus":0.24590651021378876,"score_gpt":0.4300987806398659,"score_spread":0.18419227042607714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206672430","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.026873643,0.9607957,0.0000040993796,0.00015787157,0.00012647758,0.010116955,0.00032491752,0.00007758486,0.0015227592],"genre_scores_gemma":[0.0051184883,0.9874298,0.0000057767534,0.00011774169,0.00012567706,0.002727462,0.00085396296,0.00011652405,0.0035045743],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9932974,0.0028096775,0.00071576494,0.0005792561,0.0021150203,0.0004829012],"domain_scores_gemma":[0.997731,0.0005394754,0.00037732974,0.0009921279,0.00020600363,0.00015407924],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0017035253,0.00031843077,0.0010115402,0.00028528844,0.0005050905,0.000045232722,0.00055629853,0.0002567588,0.0014308753],"category_scores_gemma":[0.0008316105,0.00022078602,0.00044432984,0.0012355696,0.00020879638,0.00006260251,0.00025794472,0.0018033332,0.000043516793],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027980428,0.0025290044,0.000026685842,0.011769227,0.00056390464,0.00010053584,0.00018813438,0.0000041881767,0.02411077,0.0009515477,0.023421332,0.9360549],"study_design_scores_gemma":[0.0006732023,0.0009808894,0.00012426627,0.001716986,0.00019718031,0.000017078393,0.000011661231,0.00007218616,0.004304089,0.00023049761,0.9914712,0.00020079403],"about_ca_topic_score_codex":0.000048515554,"about_ca_topic_score_gemma":0.0000020817542,"teacher_disagreement_score":0.9680498,"about_ca_system_score_codex":0.0002798697,"about_ca_system_score_gemma":0.00083847967,"threshold_uncertainty_score":0.999482},"labels":[],"label_agreement":null},{"id":"W4206893461","doi":"","title":"AMPK activation stimultes autophagy and ameliorates muscular dystrophy in MDX mice","year":2012,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Autophagy; AMPK; Muscular dystrophy; mdx mouse; Duchenne muscular dystrophy; Medicine; Chemistry; Cell biology; Internal medicine; Protein kinase A; Dystrophin; Biology; Phosphorylation; Biochemistry","score_opus":0.012863408208356644,"score_gpt":0.25018827311537783,"score_spread":0.2373248649070212,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206893461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9738271,0.005957748,0.012452454,0.0033261285,0.00013323258,0.0007265813,0.000038960974,0.00017409823,0.0033636715],"genre_scores_gemma":[0.98532796,0.0015805844,0.010529021,0.00019241522,0.00005743082,0.000098142606,0.00052006985,0.00005306693,0.0016412912],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99649805,0.0017397645,0.00045546182,0.0006122086,0.00034451365,0.00035001818],"domain_scores_gemma":[0.9968308,0.0006494087,0.00034308623,0.0012038995,0.000725424,0.00024735142],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0018214214,0.0003442254,0.00049137924,0.00028019428,0.00014634502,0.00014206946,0.0003423357,0.0003415096,0.00016980605],"category_scores_gemma":[0.0006486934,0.00034459995,0.00015279472,0.00032237623,0.00020875613,0.00016679858,0.00046378598,0.00066157524,0.000025367328],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006530421,0.008659747,0.07204804,0.0033194365,0.0014251277,0.00013812497,0.06209022,0.00034847768,0.37158003,0.04582935,0.0010074312,0.43290097],"study_design_scores_gemma":[0.004416107,0.0000029628397,0.44274908,0.007815789,0.0003541049,0.000031995565,0.00041408732,0.01428341,0.5149411,0.00671279,0.0071546286,0.0011239487],"about_ca_topic_score_codex":0.0009925284,"about_ca_topic_score_gemma":0.0001015567,"teacher_disagreement_score":0.43177703,"about_ca_system_score_codex":0.00013651916,"about_ca_system_score_gemma":0.00022098579,"threshold_uncertainty_score":0.9999006},"labels":[],"label_agreement":null},{"id":"W4206964923","doi":"10.1113/jp282173","title":"Time‐dependent changes in autophagy, mitophagy and lysosomes in skeletal muscle during denervation‐induced disuse","year":2022,"lang":"en","type":"article","venue":"The Journal of Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Mitophagy; Autophagy; Lysosome; Denervation; Cell biology; Mitochondrion; Muscle atrophy; TFEB; Skeletal muscle; Biology; Flux (metallurgy); Endocrinology; Internal medicine; Vacuole; Atrophy; Chemistry; Biochemistry; Medicine; Cytoplasm; Enzyme; Apoptosis","score_opus":0.012954060251750946,"score_gpt":0.26268024154110803,"score_spread":0.24972618128935709,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206964923","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99692714,0.0015045437,4.928609e-7,0.0012637955,0.0001333411,0.00013727264,0.00000306367,0.0000065795284,0.000023772667],"genre_scores_gemma":[0.99885565,0.00033320877,0.000009685861,0.000400912,0.00020395685,0.000010449176,0.000002940258,0.000013155853,0.00017001145],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99894196,0.00029833106,0.00028192796,0.000103877646,0.00018359211,0.00019031606],"domain_scores_gemma":[0.99945766,0.00011743627,0.00019289588,0.00014902856,0.00002770099,0.00005528089],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003844339,0.00010275725,0.00031269089,0.0002099585,0.000086631946,0.0000033179163,0.0001503471,0.000036765654,0.00039493552],"category_scores_gemma":[0.000031295887,0.00007241903,0.000053003554,0.00017690903,0.00006706802,0.00006299906,0.00010734032,0.00036283094,0.00000383473],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004185132,0.00024350497,0.0008878208,0.000024199235,0.000057424037,0.00014501053,0.0013125123,0.00039287773,0.9953359,0.000023598273,0.00002926548,0.0011293868],"study_design_scores_gemma":[0.0036634188,0.0006887016,0.93660825,0.000034732544,0.00004566414,0.00031162778,0.000871916,0.00031229132,0.056293044,0.0009718928,0.000100827565,0.000097617216],"about_ca_topic_score_codex":0.00003488394,"about_ca_topic_score_gemma":0.00002200501,"teacher_disagreement_score":0.93904287,"about_ca_system_score_codex":0.00009501653,"about_ca_system_score_gemma":0.00006637206,"threshold_uncertainty_score":0.4324267},"labels":[],"label_agreement":null},{"id":"W4210676524","doi":"10.3410/f.13381960.14750137","title":"Faculty Opinions recommendation of MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner.","year":2011,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Heart and Stroke Foundation of Canada","keywords":"Autophagy; Apoptosis; Cell biology; Regulator; Programmed cell death; Downregulation and upregulation; Transgene; Cell fate determination; Biology; Chemistry; Gene; Transcription factor; Biochemistry","score_opus":0.04117983429677208,"score_gpt":0.34953243731063327,"score_spread":0.3083526030138612,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210676524","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000041433555,0.0022557534,0.000004574509,0.079421915,0.00055070536,0.0020619864,0.9155266,0.000057821806,0.000079200094],"genre_scores_gemma":[0.000067043446,0.0009930766,0.0008353521,0.006896223,0.00015517823,0.0002588209,0.98821473,0.00004904425,0.0025305115],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99479145,0.0004148092,0.0019335906,0.0008710676,0.0014964738,0.0004926255],"domain_scores_gemma":[0.99281955,0.00009802229,0.0016297414,0.0017349446,0.003306359,0.00041138675],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000949664,0.00071420695,0.0014642277,0.00065409526,0.00016050712,0.00006750887,0.0011587687,0.0010217272,0.0018661533],"category_scores_gemma":[0.0016128182,0.00047305,0.0007137024,0.0021044973,0.00041109303,0.0003093359,0.00038739518,0.0010671441,0.00005989714],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000984388,0.0010005492,0.00004613434,0.008561842,0.00041180066,0.0000034093885,0.00042731664,4.185827e-8,0.000007367579,0.00009835938,0.98754156,0.0018032029],"study_design_scores_gemma":[0.0018376283,0.00016407596,0.018453008,0.024961151,0.00030959092,0.00008666442,0.00006836022,0.000008448439,0.0008137808,0.000050224728,0.9528405,0.0004065567],"about_ca_topic_score_codex":0.00011543573,"about_ca_topic_score_gemma":0.000008482981,"teacher_disagreement_score":0.07268814,"about_ca_system_score_codex":0.00021037697,"about_ca_system_score_gemma":0.0009053405,"threshold_uncertainty_score":0.99977213},"labels":[],"label_agreement":null},{"id":"W4210847887","doi":"10.1155/2022/2549772","title":"<i>Streptococcus lutetiensis</i> Induces Autophagy via Oxidative Stress in Bovine Mammary Epithelial Cells","year":2022,"lang":"en","type":"article","venue":"Oxidative Medicine and Cellular Longevity","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Beijing Municipal Natural Science Foundation; National Natural Science Foundation of China","keywords":"Autophagy; Oxidative stress; Chemistry; Microbiology; Cell biology; Biology; Apoptosis; Biochemistry","score_opus":0.016736881725390167,"score_gpt":0.2603293023260282,"score_spread":0.24359242060063802,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210847887","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98836964,0.0050829216,0.0012098281,0.0016231713,0.0004002578,0.001085845,0.0001385829,0.00009179365,0.001997952],"genre_scores_gemma":[0.9957771,0.0004899819,0.00014426498,0.0015533961,0.0003641319,0.00019382448,0.00033373883,0.000046267513,0.0010973242],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967801,0.00051668525,0.0005965803,0.0008181663,0.00074568286,0.0005427733],"domain_scores_gemma":[0.9983965,0.00021494257,0.0002803631,0.00061783544,0.00011305072,0.00037730447],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007120683,0.0004639299,0.00090880867,0.00036771104,0.00029412674,0.000016481916,0.00028123768,0.00012233038,0.0018101282],"category_scores_gemma":[0.00007962022,0.00039098496,0.00013622794,0.00068723457,0.00044236393,0.0002188522,0.00035637154,0.0008438625,0.000019110303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008326642,0.0012493101,0.005275946,0.00019381043,0.00028083564,0.0023866186,0.003957052,0.000010776483,0.9646906,0.00048568426,0.001716001,0.018920679],"study_design_scores_gemma":[0.0064935465,0.0026355437,0.017713625,0.00016935104,0.00026420061,0.00006514397,0.0026545282,0.00032262417,0.95919967,0.0011494276,0.008786546,0.0005457796],"about_ca_topic_score_codex":0.00029706318,"about_ca_topic_score_gemma":0.000018915447,"teacher_disagreement_score":0.018374898,"about_ca_system_score_codex":0.00016577628,"about_ca_system_score_gemma":0.00018417496,"threshold_uncertainty_score":0.9998542},"labels":[],"label_agreement":null},{"id":"W4210850048","doi":"10.3389/fonc.2022.812598","title":"Blockade of Uttroside B-Induced Autophagic Pro-Survival Signals Augments Its Chemotherapeutic Efficacy Against Hepatocellular Carcinoma","year":2022,"lang":"en","type":"article","venue":"Frontiers in Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Science and Engineering Research Board; Department of Science and Technology, Ministry of Science and Technology, India","keywords":"Autophagy; Hepatocellular carcinoma; Apoptosis; Bafilomycin; Cancer research; Cancer cell; Medicine; Pharmacology; Blockade; Cancer; Liver cancer; Drug; Chemistry; Internal medicine; Receptor; Biochemistry","score_opus":0.03795122370374698,"score_gpt":0.3081777791002874,"score_spread":0.2702265553965404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210850048","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99044186,0.003705806,0.000145064,0.0006260304,0.0016666314,0.0013389366,0.000024915385,0.00006931385,0.001981422],"genre_scores_gemma":[0.9964975,0.00010175049,0.0006761489,0.0014022309,0.00015586692,0.00023861742,0.000057738667,0.00006164364,0.0008084967],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99738175,0.00042661012,0.00065077684,0.0004937878,0.0004998068,0.00054727856],"domain_scores_gemma":[0.99890435,0.000094197545,0.00029917242,0.00044795824,0.000066810506,0.0001875423],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005063044,0.00028275038,0.00095538615,0.00037494555,0.00013109387,0.0000053910107,0.00034918467,0.00019308063,0.00052740285],"category_scores_gemma":[0.000051993462,0.0002928514,0.00023141432,0.0005083189,0.00010956518,0.000048591537,0.00013820725,0.00055006146,0.000012628174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0051266886,0.0069832853,0.33613932,0.00030987267,0.0011850129,0.0021370624,0.0036064961,0.00045015648,0.5966536,0.00016421893,0.003566948,0.043677367],"study_design_scores_gemma":[0.04537427,0.008433628,0.20678106,0.0001420262,0.0007660163,0.00015405359,0.0028996915,0.031271737,0.6676574,0.0013412678,0.034013204,0.0011656987],"about_ca_topic_score_codex":0.000022288836,"about_ca_topic_score_gemma":0.0000010388727,"teacher_disagreement_score":0.12935828,"about_ca_system_score_codex":0.00077424274,"about_ca_system_score_gemma":0.00073634775,"threshold_uncertainty_score":0.9999524},"labels":[],"label_agreement":null},{"id":"W4213038282","doi":"10.21203/rs.3.rs-62994/v3","title":"Inhibition of Ref(2)P, the Drosophila homologue of the p62/SQSTM1 gene, increases lifespan and leads to a decline in motor function&amp;nbsp;","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Memorial University of Newfoundland","keywords":"Drosophila (subgenus); Motor function; Gene; Function (biology); Biology; Genetics; Cell biology; Chemistry; Medicine; Physical medicine and rehabilitation","score_opus":0.061926379676068864,"score_gpt":0.38382652124690503,"score_spread":0.3219001415708362,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213038282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98787665,0.005501104,0.00004105532,0.004213288,0.000100417914,0.0017855357,0.0002636807,0.000019106852,0.00019913846],"genre_scores_gemma":[0.99636906,0.0016077089,0.000121834375,0.0005584671,0.0003313339,0.00031931838,0.00024589736,0.00003762875,0.00040874578],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99656266,0.00091597013,0.00054916844,0.0005056954,0.0011010951,0.00036539912],"domain_scores_gemma":[0.9970903,0.00054048514,0.00016648928,0.0012512784,0.00075017294,0.00020129394],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015978127,0.00022834227,0.0005637052,0.000406676,0.00013489183,0.000036026577,0.00029228735,0.00031754264,0.00017399517],"category_scores_gemma":[0.0015359513,0.00014315503,0.00023885039,0.00077890605,0.00048290697,0.000042641255,0.0013039951,0.0011630389,0.0000067810506],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016178573,0.007801146,0.46381947,0.0147015825,0.00157058,0.000813131,0.009119307,0.00085132715,0.46096042,0.0027821087,0.0072499183,0.014152435],"study_design_scores_gemma":[0.0019240457,0.00089008064,0.9508422,0.0040933443,0.00013232237,0.000040299226,0.0010058826,0.000077613426,0.035781186,0.0036727854,0.0013192873,0.00022093346],"about_ca_topic_score_codex":0.0019636415,"about_ca_topic_score_gemma":0.00082375493,"teacher_disagreement_score":0.48702273,"about_ca_system_score_codex":0.00013322933,"about_ca_system_score_gemma":0.00091976515,"threshold_uncertainty_score":0.58376926},"labels":[],"label_agreement":null},{"id":"W4213160873","doi":"10.21203/rs.3.rs-62994/v4","title":"Inhibition of Ref(2)P, the Drosophila homologue of the p62/SQSTM1 gene, increases lifespan and leads to a decline in motor function&amp;nbsp;","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Memorial University of Newfoundland","keywords":"Drosophila (subgenus); Motor function; Function (biology); Gene; Genetics; Biology; Cell biology; Medicine; Physical medicine and rehabilitation","score_opus":0.061926379676068864,"score_gpt":0.38382652124690503,"score_spread":0.3219001415708362,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213160873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98787665,0.005501104,0.00004105532,0.004213288,0.000100417914,0.0017855357,0.0002636807,0.000019106852,0.00019913846],"genre_scores_gemma":[0.99636906,0.0016077089,0.000121834375,0.0005584671,0.0003313339,0.00031931838,0.00024589736,0.00003762875,0.00040874578],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99656266,0.00091597013,0.00054916844,0.0005056954,0.0011010951,0.00036539912],"domain_scores_gemma":[0.9970903,0.00054048514,0.00016648928,0.0012512784,0.00075017294,0.00020129394],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015978127,0.00022834227,0.0005637052,0.000406676,0.00013489183,0.000036026577,0.00029228735,0.00031754264,0.00017399517],"category_scores_gemma":[0.0015359513,0.00014315503,0.00023885039,0.00077890605,0.00048290697,0.000042641255,0.0013039951,0.0011630389,0.0000067810506],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016178573,0.007801146,0.46381947,0.0147015825,0.00157058,0.000813131,0.009119307,0.00085132715,0.46096042,0.0027821087,0.0072499183,0.014152435],"study_design_scores_gemma":[0.0019240457,0.00089008064,0.9508422,0.0040933443,0.00013232237,0.000040299226,0.0010058826,0.000077613426,0.035781186,0.0036727854,0.0013192873,0.00022093346],"about_ca_topic_score_codex":0.0019636415,"about_ca_topic_score_gemma":0.00082375493,"teacher_disagreement_score":0.48702273,"about_ca_system_score_codex":0.00013322933,"about_ca_system_score_gemma":0.00091976515,"threshold_uncertainty_score":0.58376926},"labels":[],"label_agreement":null},{"id":"W4213318106","doi":"10.3389/fcell.2022.812728","title":"Autophagy in the Neuronal Ceroid Lipofuscinoses (Batten Disease)","year":2022,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Institut National de la Recherche Scientifique; Université du Québec à Montréal; Trent University","funders":"National Institute of Neurological Disorders and Stroke; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Batten disease; Autophagy; Neuroscience; Lipofuscin; Disease; Neuronal ceroid lipofuscinosis; Biology; Medicine; Genetics; Pathology; Biochemistry","score_opus":0.03294085175948726,"score_gpt":0.2953251897097549,"score_spread":0.26238433795026767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213318106","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0026654513,0.9925308,0.0000069770285,0.00007241746,0.0008230225,0.00083839206,0.00007671813,0.000022732424,0.0029634861],"genre_scores_gemma":[0.0006061502,0.9958876,0.00047699778,0.0012118338,0.00010338184,0.0003210507,0.00081777683,0.000032616437,0.00054264185],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979797,0.0003582462,0.00052312855,0.0005770782,0.00015964903,0.00040222483],"domain_scores_gemma":[0.99933726,0.00018222858,0.00012458228,0.000215255,0.000005244927,0.00013541618],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025481157,0.00039093773,0.0011027238,0.00036327736,0.00009525896,0.0000150291235,0.00031646708,0.00019237914,0.0004993962],"category_scores_gemma":[0.000028955563,0.00025754923,0.00019123756,0.00036379258,0.00019336348,0.000032271306,0.00018016362,0.000608588,0.000021664175],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015597034,0.0003907726,0.007414524,0.002894588,0.000112273236,0.0006567188,0.00034585575,1.0520319e-7,0.0000024935175,0.000052036714,0.0120445145,0.97593015],"study_design_scores_gemma":[0.0007546433,0.00011036578,0.0053389654,0.00037810198,0.00014779592,0.00007011085,0.00026568407,0.0000025528348,0.0000035504377,0.00031183887,0.9923419,0.00027449528],"about_ca_topic_score_codex":0.000017513106,"about_ca_topic_score_gemma":0.0000029056152,"teacher_disagreement_score":0.9802974,"about_ca_system_score_codex":0.00020451748,"about_ca_system_score_gemma":0.0006364745,"threshold_uncertainty_score":0.99998766},"labels":[],"label_agreement":null},{"id":"W4213450731","doi":"10.3389/fpls.2022.817251","title":"ROOT HAIR DEFECTIVE3 Is a Receptor for Selective Autophagy of the Endoplasmic Reticulum in Arabidopsis","year":2022,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Endoplasmic reticulum; Cell biology; Arabidopsis; ATG8; Autophagy; Unfolded protein response; Mutant; Homomeric; Biology; Chemistry; Receptor; Biochemistry; Protein subunit; Gene","score_opus":0.007366316235349674,"score_gpt":0.23857300101505524,"score_spread":0.23120668477970557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213450731","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957642,0.00047427637,0.0003564063,0.0003090064,0.0010649855,0.0008984596,0.00022779877,0.00001673936,0.0008881588],"genre_scores_gemma":[0.99762166,0.000019201232,0.0013775635,0.00036997278,0.000021381715,0.00022020213,0.0000067016795,0.000009444868,0.00035388337],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99851376,0.00007604402,0.00023412133,0.00037724923,0.00045701815,0.0003418312],"domain_scores_gemma":[0.9994303,0.00007474688,0.00011436061,0.00026705334,0.00005021096,0.00006334262],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061051646,0.000111689435,0.00026733716,0.0003191135,0.00020533652,0.000007417868,0.0003834173,0.000033711458,0.000044785702],"category_scores_gemma":[0.00018255625,0.000087049346,0.00009791188,0.0014260203,0.0003621612,0.00008915745,0.00009753912,0.00024026327,0.0000010895689],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022747032,0.0009123144,0.8827163,0.000107648506,0.00009454572,0.000040630573,0.009760687,0.0007421368,0.038472787,0.0013474509,0.060906626,0.002624155],"study_design_scores_gemma":[0.0043602195,0.0008178238,0.40836307,0.00015745523,0.00005640742,0.00007108748,0.002253399,0.019613758,0.5509074,0.0053641843,0.007726017,0.00030918256],"about_ca_topic_score_codex":0.000054880875,"about_ca_topic_score_gemma":0.000018177463,"teacher_disagreement_score":0.5124346,"about_ca_system_score_codex":0.00039344718,"about_ca_system_score_gemma":0.0005797156,"threshold_uncertainty_score":0.35497692},"labels":[],"label_agreement":null},{"id":"W4213474666","doi":"","title":"Modulation of autophagic activity by chemotactic GPCRs controls the invasive potential of glioblastoma cells","year":2016,"lang":"en","type":"article","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Autophagy; Chemotaxis; Glioblastoma; Modulation (music); G protein-coupled receptor; Cell biology; Chemistry; Neuroscience; Biology; Cancer research; Signal transduction; Receptor; Physics; Biochemistry","score_opus":0.006174314274957367,"score_gpt":0.2154176309031774,"score_spread":0.20924331662822002,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213474666","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9711959,0.00029684338,0.021728322,0.0043790247,0.000059809303,0.00038770543,0.000047702553,0.000043927408,0.0018607602],"genre_scores_gemma":[0.9969663,0.00021954802,0.00042748696,0.00007453075,0.000012820575,0.000016014903,0.0000147014325,0.00001872014,0.0022498628],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99773896,0.001180706,0.00031216725,0.0002456284,0.00034389322,0.00017864368],"domain_scores_gemma":[0.9965751,0.0010841152,0.00043646403,0.0009039588,0.0009004853,0.00009983498],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011649131,0.00014092858,0.00028109038,0.000070909235,0.00010370866,0.000017753078,0.0002871663,0.00009020785,0.00023861113],"category_scores_gemma":[0.00055956625,0.00009244678,0.00016818261,0.00022385614,0.00031275288,0.0001361215,0.00008201147,0.00010618743,0.000013900362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021016481,0.000515812,0.00060459913,0.00004350321,0.00009943835,0.0000019030516,0.00062079064,0.0000042648508,0.9720796,0.0017918408,0.00026061336,0.023767475],"study_design_scores_gemma":[0.0018218281,0.000003343867,0.026972514,0.0003487369,0.00007353154,0.000006168883,0.000031020645,0.0017133984,0.9680805,0.0005268461,0.00033398884,0.0000880863],"about_ca_topic_score_codex":0.00015089392,"about_ca_topic_score_gemma":0.00003514666,"teacher_disagreement_score":0.026367916,"about_ca_system_score_codex":0.000049170943,"about_ca_system_score_gemma":0.00015826424,"threshold_uncertainty_score":0.37698704},"labels":[],"label_agreement":null},{"id":"W4214825026","doi":"10.1016/j.jconrel.2022.03.001","title":"Targeting autophagy, oxidative stress, and ER stress for neurodegenerative disease treatment","year":2022,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":174,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"National Institutes of Health","keywords":"Autophagy; Neurodegeneration; Crosstalk; Unfolded protein response; Oxidative stress; Endoplasmic reticulum; Neuroprotection; Cell biology; Neuroscience; Biology; Chemistry; Disease; Medicine; Biochemistry; Apoptosis","score_opus":0.03416087975541528,"score_gpt":0.34033356042980817,"score_spread":0.3061726806743929,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4214825026","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006843306,0.99392295,0.0001440813,0.00020357633,0.00047505074,0.0034792006,0.0010154041,0.000021464315,0.00005391429],"genre_scores_gemma":[0.0006754839,0.9954439,0.0001793965,0.00023358654,0.0013219714,0.00055063225,0.00029320482,0.00010641292,0.0011954407],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967054,0.0005816274,0.0014258631,0.0004215818,0.0005015844,0.00036395056],"domain_scores_gemma":[0.99548,0.0011500522,0.0020108286,0.00031949274,0.00026170834,0.0007779183],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033933014,0.0006639286,0.0039672684,0.00035220594,0.00026309476,0.00006239758,0.00018664048,0.00014819969,0.0004704083],"category_scores_gemma":[0.0007383259,0.00041047944,0.00199215,0.000157734,0.00009333803,0.00016432874,0.000048272963,0.0005617677,0.0000025394256],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.022981254,0.0035140468,0.000026708358,0.0118482085,0.012929626,0.005483312,0.00030413087,0.00018702645,0.000016644342,0.00040299434,0.0020469981,0.94025904],"study_design_scores_gemma":[0.034701668,0.0029203892,0.000013859877,0.0053200447,0.019803884,0.00012031403,0.00013445616,0.000496713,0.000036148514,0.00010119499,0.93590975,0.00044156268],"about_ca_topic_score_codex":0.000003209297,"about_ca_topic_score_gemma":3.7721958e-7,"teacher_disagreement_score":0.9398175,"about_ca_system_score_codex":0.00033642288,"about_ca_system_score_gemma":0.0019712797,"threshold_uncertainty_score":0.9998347},"labels":[],"label_agreement":null},{"id":"W4214852955","doi":"10.1152/japplphysiol.00661.2021","title":"Effect of extracellular hyperosmolality during normothermia and hyperthermia on the autophagic response in peripheral blood mononuclear cells from young men","year":2022,"lang":"en","type":"article","venue":"Journal of Applied Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Osmotic concentration; Hyperthermia; Peripheral blood mononuclear cell; Extracellular; Internal medicine; Heat shock protein; Autophagy; Dehydration; Chemistry; Hsp70; Endocrinology; Heat shock; Saline; Extracellular fluid; Andrology; Medicine; Apoptosis; Biochemistry; In vitro","score_opus":0.005077522457032008,"score_gpt":0.22209736003115002,"score_spread":0.21701983757411802,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4214852955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998593,0.00065732485,6.446295e-7,0.00012399307,0.00006886254,0.00029072812,0.000012257045,0.000007692526,0.00024551497],"genre_scores_gemma":[0.9995193,0.00006473082,0.00002861408,0.00018028826,0.00010682767,0.00001681229,0.0000018976218,0.000027538004,0.000053997876],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998446,0.0005416039,0.00040730753,0.00018551662,0.00023301312,0.00018657593],"domain_scores_gemma":[0.99888307,0.00043825252,0.0003202901,0.0002662931,0.000019612426,0.000072480376],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007899465,0.00016689968,0.0005429742,0.000089629444,0.00010855659,0.0000054500483,0.00017717555,0.00006812521,0.0005043807],"category_scores_gemma":[0.000018476352,0.00010908715,0.000135895,0.00010989058,0.00011265317,0.000025641595,0.00006618349,0.0005316244,0.0000025685044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.04911652,0.00028981804,0.00037346696,0.000028080725,0.00020544912,0.00014656353,0.001096463,0.00048141993,0.9477392,0.00005160208,0.000017819166,0.00045359987],"study_design_scores_gemma":[0.008610402,0.0036301094,0.34498253,0.000039660576,0.00020961759,0.00010852073,0.0005189085,0.00037548773,0.6404277,0.00084706105,0.00010027614,0.00014971815],"about_ca_topic_score_codex":0.000023098737,"about_ca_topic_score_gemma":2.7075515e-7,"teacher_disagreement_score":0.34460908,"about_ca_system_score_codex":0.00006906462,"about_ca_system_score_gemma":0.000062287094,"threshold_uncertainty_score":0.5522615},"labels":[],"label_agreement":null},{"id":"W4214901048","doi":"10.3389/fcell.2022.823251","title":"Tumor Suppressing Subtransferable Candidate 4 Expression Prevents Autophagy-Induced Cell Death Following Temozolomide Treatment in Glioblastoma Cells","year":2022,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; CancerCare Manitoba Foundation","keywords":"Autophagy; Temozolomide; Programmed cell death; Cancer research; Downregulation and upregulation; Biology; Cell; Cancer cell; Cell growth; Cancer; Chemistry; Apoptosis; Glioma; Gene; Genetics","score_opus":0.009531566111296024,"score_gpt":0.24138218474354123,"score_spread":0.2318506186322452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4214901048","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99565375,0.0018704989,0.00007721338,0.00002368634,0.0007509798,0.0006710901,0.000031594976,0.00003732709,0.0008838794],"genre_scores_gemma":[0.99456954,0.0002068848,0.003881871,0.00024636774,0.000022906175,0.00021118649,0.00008162347,0.000028724307,0.00075092306],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982178,0.00018786758,0.0004121798,0.00053453294,0.0001384337,0.00050917297],"domain_scores_gemma":[0.99958813,0.000040932344,0.000068369525,0.00014351067,0.0000057493867,0.00015328912],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018186515,0.0002857568,0.0005167841,0.00031113223,0.00022741173,0.000013868032,0.000121451594,0.0000991561,0.000167364],"category_scores_gemma":[0.0000033227238,0.00025368918,0.000095883624,0.00020609846,0.00003073695,0.000079405574,0.00010502313,0.00023840717,0.000004808201],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013421485,0.0008524984,0.20984097,0.000060015616,0.000054234202,0.00093449187,0.0018094247,0.000018356459,0.7809866,0.0000017658077,0.00041056288,0.0036889429],"study_design_scores_gemma":[0.0058969674,0.00083040906,0.010619319,0.000057540656,0.000032957447,0.000035098918,0.0014649106,0.00021827739,0.9789407,0.00026624047,0.0013393844,0.00029817683],"about_ca_topic_score_codex":0.00015559926,"about_ca_topic_score_gemma":0.000016626293,"teacher_disagreement_score":0.19922166,"about_ca_system_score_codex":0.0005895672,"about_ca_system_score_gemma":0.00028206926,"threshold_uncertainty_score":0.99999154},"labels":[],"label_agreement":null},{"id":"W4214923702","doi":"10.1101/2022.03.02.482658","title":"Critical role of PCYT2 in muscle health and aging","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Guelph","funders":"National Institutes of Health; Science for Life Laboratory; Agence Nationale de la Recherche; Austrian Science Fund; Karolinska Institutet; European Commission; Österreichische Forschungsförderungsgesellschaft; Österreichischen Akademie der Wissenschaften; Wellcome Trust","keywords":"Muscle weakness; Exercise intolerance; Skeletal muscle; Biology; Myocyte; Dysferlin; Failure to thrive; Weakness; Muscular dystrophy; Sarcopenia; Cell biology; Internal medicine; Medicine; Endocrinology; Heart failure; Genetics; Anatomy","score_opus":0.01337662183326463,"score_gpt":0.27470146649461247,"score_spread":0.26132484466134787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4214923702","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9769063,0.021215819,0.0000415652,0.00081100484,0.00027246165,0.0005050073,0.00011044775,0.00011485433,0.000022545295],"genre_scores_gemma":[0.9964653,0.0011404785,0.0011690833,0.000884225,0.00015701955,0.000108174965,4.7315754e-7,0.000072784525,0.0000024193293],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980336,0.0001427967,0.00049377297,0.000596433,0.00033601717,0.0003973888],"domain_scores_gemma":[0.9985001,0.000082735285,0.00018154745,0.00072376017,0.00012467371,0.00038714867],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004969691,0.00027912948,0.00066711294,0.00029627033,0.00008228411,0.000028255869,0.00017265555,0.00017912408,0.00018755111],"category_scores_gemma":[0.00021548521,0.00031174993,0.00010251422,0.00029788713,0.00013311801,0.00006249251,0.0003470726,0.0007464654,0.000003937364],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005025046,0.0025708682,0.239358,0.009138116,0.00052312884,0.0008175769,0.0005459522,0.000048879185,0.7327162,0.01324415,0.00036033036,0.00017427301],"study_design_scores_gemma":[0.002074294,0.000371907,0.9373716,0.001425444,0.00013421215,6.4815275e-8,0.00010987081,0.0005543642,0.049776953,0.000056659377,0.007460955,0.00066364254],"about_ca_topic_score_codex":0.00014395673,"about_ca_topic_score_gemma":0.0000012386282,"teacher_disagreement_score":0.69801366,"about_ca_system_score_codex":0.00022465162,"about_ca_system_score_gemma":0.0011113727,"threshold_uncertainty_score":0.9999335},"labels":[],"label_agreement":null},{"id":"W4220677850","doi":"10.1016/j.chembiol.2022.03.006","title":"A selective PPM1A inhibitor activates autophagy to restrict the survival of Mycobacterium tuberculosis","year":2022,"lang":"en","type":"article","venue":"Cell chemical biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Ottawa; Lung Health Foundation; Russian Science Foundation; National Sanitarium Association; Science and Technology Commission of Shanghai Municipality","keywords":"Autophagy; Mycobacterium tuberculosis; Biology; Druggability; Tuberculosis; Biochemistry; Medicine; Gene","score_opus":0.011119351007014347,"score_gpt":0.2606821534901134,"score_spread":0.2495628024830991,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220677850","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99601746,0.00040819918,0.000007967613,0.000962894,0.00025995602,0.00033044297,0.000059343674,0.000044769084,0.0019089963],"genre_scores_gemma":[0.99831563,0.000029076122,0.00005449169,0.00097069104,0.00024286837,0.000121577825,0.000067102425,0.00001873986,0.00017983456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988999,0.00014215575,0.00023701994,0.0003035,0.00013736078,0.000280092],"domain_scores_gemma":[0.9991489,0.0002807804,0.0000795884,0.00029885862,0.00006475397,0.00012709155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001368759,0.00014656907,0.00033004672,0.00006308499,0.000085193264,0.0000032334483,0.00019440909,0.00009636939,0.0005175142],"category_scores_gemma":[0.00009467872,0.000102031205,0.000143203,0.0004008111,0.000121822886,0.000014358632,0.00021105031,0.00032617277,0.0000194156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007551127,0.00029327453,0.002089422,0.00002406618,0.00009128086,0.000006696458,0.00027191834,0.0000016354851,0.9941165,0.00016529259,0.0015797307,0.0006050572],"study_design_scores_gemma":[0.0007430105,0.00057927234,0.0046791504,0.000005363353,0.000055046195,0.00001050524,0.0001612654,0.000010082939,0.9856186,0.00040409816,0.0076274187,0.000106177475],"about_ca_topic_score_codex":0.00003706586,"about_ca_topic_score_gemma":2.7592043e-7,"teacher_disagreement_score":0.008497904,"about_ca_system_score_codex":0.000106088904,"about_ca_system_score_gemma":0.00011535096,"threshold_uncertainty_score":0.56664175},"labels":[],"label_agreement":null},{"id":"W4220719430","doi":"10.3389/fonc.2022.808475","title":"Interplay Between Non-Coding RNAs and Programmed Cell Death Proteins","year":2022,"lang":"en","type":"review","venue":"Frontiers in Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; Centennial College; University of Ottawa","funders":"","keywords":"MALAT1; microRNA; MEG3; Biology; Disease; Context (archaeology); Programmed cell death; Computational biology; RNA; Long non-coding RNA; Bioinformatics; Apoptosis; Cancer research; Genetics; Medicine; Gene; Internal medicine","score_opus":0.04738024745196958,"score_gpt":0.3903103726536561,"score_spread":0.34293012520168653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220719430","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00010153318,0.9884583,0.0017404639,0.00006183661,0.0010088598,0.0033809936,0.000035404995,0.000058039554,0.0051546027],"genre_scores_gemma":[0.00012377187,0.98991334,0.0065105106,0.00016134883,0.00041154324,0.0014188787,0.000303369,0.000086458596,0.0010707506],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99775875,0.00030716677,0.00065900903,0.00058045675,0.00019470713,0.0004999157],"domain_scores_gemma":[0.9988605,0.00016887941,0.00035358386,0.0003692418,0.00001602481,0.00023180027],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00044172097,0.00041713958,0.0026467869,0.00051317894,0.00008847604,0.000015592606,0.00027344286,0.0005453753,0.00021621311],"category_scores_gemma":[0.000059763606,0.00035537776,0.0003221551,0.00032166968,0.00012728604,0.00004054938,0.00019804665,0.0011627198,0.00001124489],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006488281,0.0002451558,0.0011502128,0.0059110415,0.00032236078,0.00064701657,0.00025223038,2.6885926e-8,3.407908e-7,0.00001129215,0.0033583066,0.9880371],"study_design_scores_gemma":[0.0014577236,0.0011232342,0.000108373424,0.0019337932,0.0010845616,0.00007747764,0.00012960973,0.000009428361,0.000006907237,0.00011819263,0.993664,0.00028669136],"about_ca_topic_score_codex":0.000024555397,"about_ca_topic_score_gemma":0.0000026856137,"teacher_disagreement_score":0.9903057,"about_ca_system_score_codex":0.00095140876,"about_ca_system_score_gemma":0.00096027023,"threshold_uncertainty_score":0.9998898},"labels":[],"label_agreement":null},{"id":"W4220752430","doi":"10.1165/rcmb.2022-0064ed","title":"Muscle Wasting in Chronic Obstructive Pulmonary Disease: Not Enough Autophagy?","year":2022,"lang":"en","type":"letter","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Pulmonary disease; Wasting; Autophagy; Medicine; Chronic wasting disease; Muscle disease; Intensive care medicine; Disease; Internal medicine; Cardiology; Bioinformatics; Biology; Genetics","score_opus":0.010020306484121527,"score_gpt":0.2667721557461966,"score_spread":0.25675184926207506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220752430","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9311714,0.04233714,0.00012645533,0.024943715,0.0004532995,0.00039581652,0.000085453496,0.00002476276,0.00046196798],"genre_scores_gemma":[0.57278776,0.0013096253,0.0002729689,0.42327264,0.0019064673,0.000035166242,0.00007563082,0.00010548517,0.0002342691],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.997659,0.00054473086,0.0006268191,0.0004345607,0.00028060246,0.00045425742],"domain_scores_gemma":[0.998376,0.00015319645,0.0008252839,0.00032791455,0.000085446205,0.00023213823],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023980724,0.00035556353,0.0009172064,0.00043699102,0.000079870515,0.000010934903,0.0002524687,0.00020145341,0.00031315256],"category_scores_gemma":[0.00006180822,0.0002835735,0.00029766452,0.00028525465,0.0005339461,0.000041923693,0.000117472315,0.00188442,0.0000024335193],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006040857,0.00058176275,0.00421075,0.0014042697,0.0011496979,0.27426568,0.00052644045,0.00013186813,0.38153172,0.00007299986,0.019531587,0.3105524],"study_design_scores_gemma":[0.0015929906,0.0044901595,0.0082817795,0.00018513999,0.00035539828,0.0005364794,0.0001779076,0.0000187535,0.0051496187,0.00014080951,0.9786243,0.00044666222],"about_ca_topic_score_codex":0.000017067434,"about_ca_topic_score_gemma":4.3482714e-7,"teacher_disagreement_score":0.95909274,"about_ca_system_score_codex":0.00030724492,"about_ca_system_score_gemma":0.0013336501,"threshold_uncertainty_score":0.9999616},"labels":[],"label_agreement":null},{"id":"W4220784485","doi":"10.1186/s13046-022-02293-6","title":"Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response","year":2022,"lang":"en","type":"review","venue":"Journal of Experimental & Clinical Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":146,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Cancer Science Institute of Singapore, National University of Singapore; Ministry of Education, India; National Research Foundation; Terry Fox Foundation; Ministry of Education - Singapore; National Research Foundation Singapore; National Institutes of Health; National University of Singapore","keywords":"Autophagy; Prostate cancer; Cancer research; Cancer; Medicine; Prostate; Metastasis; Cancer cell; PI3K/AKT/mTOR pathway; Biology; Apoptosis; Internal medicine","score_opus":0.640619251587378,"score_gpt":0.6972159774264259,"score_spread":0.05659672583904796,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220784485","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.034844793,0.9595173,0.0000021134194,0.00084138924,0.0014851965,0.0032098864,0.0000688965,0.000015962047,0.0000144748055],"genre_scores_gemma":[0.0047733467,0.9904054,0.00021723393,0.00050451217,0.0022632822,0.0011989321,0.00001092189,0.00013825973,0.00048810677],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9840705,0.007023705,0.0053900364,0.0010127021,0.0016200092,0.0008830599],"domain_scores_gemma":[0.9698799,0.02666604,0.0016675066,0.0005518907,0.00040926773,0.00082538783],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.03136725,0.0005029984,0.004011589,0.00056055543,0.00025193676,0.00008809626,0.0007740701,0.0005404075,0.0014289322],"category_scores_gemma":[0.006554376,0.0003710487,0.001962701,0.00069302734,0.0009274709,0.00024051574,0.00047896875,0.005283197,0.0000069208672],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.047664117,0.0026805925,0.0037866065,0.0032594923,0.001399687,0.0008188193,0.00024765817,0.0000015601576,0.00006923758,0.000017076283,0.002624763,0.9374304],"study_design_scores_gemma":[0.0068657016,0.012084687,0.0017474837,0.019213175,0.0008534672,0.00013477397,0.0003429708,0.000054359152,0.00005445329,0.000081834194,0.95817584,0.00039124777],"about_ca_topic_score_codex":0.000078499834,"about_ca_topic_score_gemma":0.0000060242705,"teacher_disagreement_score":0.9555511,"about_ca_system_score_codex":0.00128576,"about_ca_system_score_gemma":0.008137738,"threshold_uncertainty_score":0.9998742},"labels":[],"label_agreement":null},{"id":"W4220788803","doi":"10.1007/s00018-022-04191-8","title":"Ubr1-induced selective endophagy/autophagy protects against the endosomal and Ca2+-induced proteostasis disease stress","year":2022,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Flinders University; Pohang University of Science and Technology; EMBL Australia; Seoul National University; California Institute of Technology","keywords":"Endosome; Proteostasis; Autophagy; Cell biology; ESCRT; Ubiquitin; BAG3; Ubiquitin ligase; Biology; Lysosome; Biochemistry; Intracellular; Enzyme; Apoptosis","score_opus":0.01766607230592466,"score_gpt":0.25754314640854115,"score_spread":0.2398770741026165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220788803","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9889344,0.0070322626,0.000097939126,0.0011396497,0.00014301651,0.0019293034,0.000031828524,0.00007166458,0.00061991665],"genre_scores_gemma":[0.99693656,0.0000951833,0.00009810191,0.0021058905,0.000092305134,0.00054960494,0.000018268047,0.000026673733,0.000077396566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975002,0.00032956878,0.00023991698,0.00069775764,0.00075523206,0.00047735788],"domain_scores_gemma":[0.9988796,0.00006164156,0.00012461354,0.0003532421,0.00006510316,0.0005157788],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.00045460692,0.00027815078,0.00029443685,0.00015007726,0.001375113,0.00008941747,0.0002789157,0.000050276543,0.00004812804],"category_scores_gemma":[0.00017524688,0.00020029877,0.0001245408,0.0005620088,0.0003828363,0.00011782299,0.00025613172,0.0003622013,0.0000028256663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037842666,0.00037187882,0.0015394512,0.0001265168,0.00020187678,0.0012460159,0.0013335645,0.00004637366,0.98466825,0.0015179043,0.000051049214,0.008518695],"study_design_scores_gemma":[0.0020388395,0.0010362962,0.007983218,0.000051947416,0.0001662844,0.000059651768,0.0014341109,0.0017384263,0.98373127,0.00094621995,0.00043057525,0.0003831529],"about_ca_topic_score_codex":0.000052572468,"about_ca_topic_score_gemma":0.0000013399634,"teacher_disagreement_score":0.008135542,"about_ca_system_score_codex":0.000038819446,"about_ca_system_score_gemma":0.0006650095,"threshold_uncertainty_score":0.99992496},"labels":[],"label_agreement":null},{"id":"W4220832674","doi":"10.1016/j.pharmthera.2022.108171","title":"Enhancing autophagy in Alzheimer's disease through drug repositioning","year":2022,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; CancerCare Manitoba; Research Manitoba; St. Boniface Hospital; University of Manitoba","funders":"National Institute of General Medical Sciences","keywords":"Autophagy; Drug repositioning; Repurposing; Drug; Disease; Medicine; Drug development; Drug discovery; Downregulation and upregulation; Pharmacology; Bioinformatics; Neuroscience; Biology; Apoptosis; Pathology","score_opus":0.10775986567795742,"score_gpt":0.42727322396027134,"score_spread":0.3195133582823139,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220832674","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00031675983,0.9947398,0.000023622619,0.0003604299,0.00159969,0.0018450486,0.000059498314,0.00022805219,0.0008271491],"genre_scores_gemma":[0.0004237062,0.98538965,0.00015419515,0.01129673,0.00068080437,0.0010450467,0.00042987347,0.00019369689,0.0003862707],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99618155,0.00078296906,0.0010858472,0.00083171524,0.00040495608,0.00071297266],"domain_scores_gemma":[0.9980759,0.0005128575,0.00051409745,0.0005837865,0.000042799722,0.0002705636],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00040066964,0.00070324756,0.001946867,0.0003257145,0.0002945254,0.000027395408,0.00040801303,0.00024371917,0.0045131766],"category_scores_gemma":[0.0000062396093,0.0006585286,0.00083627267,0.0006619185,0.00017080808,0.00013258329,0.00018750984,0.001536206,0.00011511125],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007759847,0.0025718182,0.00005716382,0.008217838,0.013028019,0.008477104,0.0019452007,0.000024680903,0.00019334152,0.00028294444,0.0016245123,0.9628014],"study_design_scores_gemma":[0.0013593459,0.00009372294,0.00002198841,0.0015587978,0.02240567,0.00017225296,0.000047706595,0.000042428917,0.00039538112,0.00023347157,0.9731543,0.0005149169],"about_ca_topic_score_codex":0.000018682244,"about_ca_topic_score_gemma":0.000002039794,"teacher_disagreement_score":0.9715298,"about_ca_system_score_codex":0.00047667278,"about_ca_system_score_gemma":0.0013824687,"threshold_uncertainty_score":0.9995866},"labels":[],"label_agreement":null},{"id":"W4220838985","doi":"10.3390/curroncol29030141","title":"Autophagy Agents in Clinical Trials for Cancer Therapy: A Brief Review","year":2022,"lang":"en","type":"review","venue":"Current Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Autophagy; Hydroxychloroquine; Medicine; Clinical trial; Chloroquine; Lymphoma; Food and drug administration; Cancer; Pharmacology; Immunology; Internal medicine; Biology; Malaria; Disease","score_opus":0.812559000681436,"score_gpt":0.6858974742419875,"score_spread":0.1266615264394485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220838985","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000009746142,0.9827112,0.000010040588,0.00037126816,0.0064940215,0.009624601,0.0003413424,0.00006002034,0.00037773655],"genre_scores_gemma":[3.2072376e-7,0.98177797,0.000026728052,0.0031026476,0.0019220585,0.011556362,0.0010123237,0.000097272816,0.00050429074],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9905631,0.0042076777,0.003554711,0.0008610943,0.000302802,0.00051060604],"domain_scores_gemma":[0.99374294,0.0034447722,0.0017567297,0.0006865026,0.000079293735,0.00028978824],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0077208383,0.0005493302,0.008665678,0.00024743477,0.0000696645,0.00000834071,0.00042270575,0.0005078116,0.0090751685],"category_scores_gemma":[0.0024588846,0.00039911878,0.0030830645,0.00044968692,0.0001108314,0.000031114883,0.000115889015,0.0012886319,0.00004734836],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000203612,0.0015154842,0.000022280075,0.04057935,0.0006163189,0.000074599615,0.00001777554,2.2266487e-8,1.6166984e-8,0.000061220846,0.06655612,0.8903532],"study_design_scores_gemma":[0.004842159,0.0009054344,0.000051986015,0.03223627,0.003144727,0.000035452595,0.0000025680893,0.0000048486895,1.1675368e-7,0.00007254963,0.95840186,0.00030200352],"about_ca_topic_score_codex":0.000010260012,"about_ca_topic_score_gemma":0.000005949894,"teacher_disagreement_score":0.89184576,"about_ca_system_score_codex":0.0008231162,"about_ca_system_score_gemma":0.004284669,"threshold_uncertainty_score":0.99984604},"labels":[],"label_agreement":null},{"id":"W4220847491","doi":"10.1080/27694127.2022.2047267","title":"snz/SNX25 at the crossroad of endocytosis and lipid handling in autophagy","year":2022,"lang":"en","type":"article","venue":"Autophagy Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Sorting nexin; Cell biology; Endocytosis; Endosome; Biology; BAG3; Regulator; Intracellular; Cell; Gene; Genetics; Apoptosis","score_opus":0.009520686446920966,"score_gpt":0.26349770715272736,"score_spread":0.2539770207058064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220847491","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9871682,0.008856167,0.000011026008,0.0004367048,0.0004867308,0.0005534868,0.000015542457,0.00007435452,0.0023977899],"genre_scores_gemma":[0.99479824,0.00022741912,0.00006134104,0.0008512557,0.00011394021,0.00017480784,0.00004675204,0.00003881184,0.0036874441],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9976931,0.00012141551,0.0007554524,0.00050048874,0.00054205745,0.00038744725],"domain_scores_gemma":[0.998511,0.00015511467,0.0003935423,0.0007518496,0.000053544176,0.0001349083],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007222812,0.00022600748,0.00052367913,0.00016445911,0.00035795465,0.00001931097,0.00011944396,0.00007313745,0.0015843962],"category_scores_gemma":[0.00011792715,0.00017742648,0.00018001508,0.00039024526,0.00021570515,0.00008111011,0.00033952933,0.00033858433,0.0000056692083],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002454849,0.0026430537,0.506287,0.0006288824,0.0011825645,0.03126526,0.010071527,0.0012511124,0.39100972,0.0016914682,0.005335681,0.04617888],"study_design_scores_gemma":[0.0042068074,0.000760928,0.5203523,0.00012355449,0.00029816662,0.008837176,0.0005578874,0.0007820465,0.39163527,0.0013611747,0.07058487,0.00049980346],"about_ca_topic_score_codex":0.0002828222,"about_ca_topic_score_gemma":0.000023854935,"teacher_disagreement_score":0.06524919,"about_ca_system_score_codex":0.00017835252,"about_ca_system_score_gemma":0.00030173382,"threshold_uncertainty_score":0.9993283},"labels":[],"label_agreement":null},{"id":"W4220985388","doi":"10.15252/embj.2021109049","title":"Macrophage mitochondrial bioenergetics and tissue invasion are boosted by an Atossa‐Porthos axis in Drosophila","year":2022,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Institute of Science and Technology Austria; National Institutes of Health; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; H2020 European Research Council; Austrian Science Fund; National Institute of General Medical Sciences; Wirtschaftsagentur Wien","keywords":"Biology; Bioenergetics; Drosophila (subgenus); Macrophage; Mitochondrion; Cell biology; Genetics; Gene","score_opus":0.014898703575282357,"score_gpt":0.274294536753297,"score_spread":0.2593958331780147,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220985388","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925285,0.0037876652,0.000022526065,0.0027279179,0.0004558029,0.00024667347,0.00003718205,0.000022650796,0.00017108368],"genre_scores_gemma":[0.99660736,0.00048789562,0.00009950571,0.0013481096,0.00054752664,0.000011151335,0.000031723914,0.00003250964,0.0008342396],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985552,0.0002708967,0.00031628888,0.00018891665,0.00041294965,0.00025574863],"domain_scores_gemma":[0.99923337,0.000037504447,0.00017741491,0.00026830792,0.000039960592,0.00024342394],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00036116212,0.00015200685,0.00024952122,0.00010341576,0.00042868865,0.00004513331,0.00018471696,0.000049711165,0.0009331367],"category_scores_gemma":[0.00003483874,0.000109084394,0.00006107329,0.00020030623,0.00008857373,0.00008778396,0.000095527605,0.0006489432,0.0000059653707],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00603182,0.0027328623,0.051689718,0.000106061336,0.00042029057,0.011096246,0.010684492,0.00034293186,0.82129717,0.0005325836,0.05874636,0.036319446],"study_design_scores_gemma":[0.058116335,0.011260825,0.24197316,0.00077128824,0.0012150087,0.031611804,0.020043768,0.0047538546,0.2836935,0.030076705,0.31379822,0.0026855383],"about_ca_topic_score_codex":0.000026469592,"about_ca_topic_score_gemma":0.000009503334,"teacher_disagreement_score":0.53760374,"about_ca_system_score_codex":0.000072016606,"about_ca_system_score_gemma":0.00008879985,"threshold_uncertainty_score":0.99998015},"labels":[],"label_agreement":null},{"id":"W4221028349","doi":"10.1016/j.bbadis.2022.166391","title":"The unfolded protein response transducer IRE1α promotes reticulophagy in podocytes","year":2022,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Consejo Nacional de Ciencia y Tecnología; Fonds de Recherche du Québec - Santé; Kidney Foundation of Canada","keywords":"Tunicamycin; Unfolded protein response; Endoplasmic reticulum; Cell biology; Podocyte; Autophagy; ATF6; Biology; Chemistry; Endocrinology; Internal medicine; Kidney; Biochemistry; Apoptosis; Medicine","score_opus":0.007782845584913847,"score_gpt":0.25861192875651046,"score_spread":0.25082908317159663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221028349","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9798422,0.0013483575,0.0000064550904,0.016457403,0.00006603696,0.0018605572,0.00023630158,0.000089996414,0.00009270744],"genre_scores_gemma":[0.9975762,0.00008394604,0.00014454983,0.0010869304,0.000043916334,0.0006886287,0.0001242542,0.00009236185,0.00015924648],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99632424,0.0009889483,0.00060391193,0.0006510856,0.0009030364,0.00052875275],"domain_scores_gemma":[0.99787587,0.00018998965,0.00026089555,0.001161445,0.000105792555,0.00040599945],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000573565,0.00040808006,0.0005074367,0.00024136344,0.0002769975,0.000045054927,0.00055199413,0.00007385092,0.0001460622],"category_scores_gemma":[0.00030354445,0.00032909564,0.0005751789,0.000807979,0.0003508609,0.00009317242,0.00018757499,0.00039093863,0.00000951937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.017735165,0.0018702814,0.000020538668,0.00013126363,0.00027620723,0.00030874275,0.0004176288,0.000008378264,0.97784024,0.00064582255,0.000156981,0.00058873696],"study_design_scores_gemma":[0.0027776654,0.00085976784,0.031079356,0.0001413706,0.00030118597,0.0000058075148,0.00022153599,0.00013543462,0.9621922,0.0016417634,0.0002798401,0.00036407902],"about_ca_topic_score_codex":0.000024786492,"about_ca_topic_score_gemma":0.0000012833008,"teacher_disagreement_score":0.031058816,"about_ca_system_score_codex":0.00012943344,"about_ca_system_score_gemma":0.00079806277,"threshold_uncertainty_score":0.99991614},"labels":[],"label_agreement":null},{"id":"W4221091910","doi":"10.3390/life12030442","title":"Trehalose Activates Hepatic and Myocardial Autophagy and Has Anti-Inflammatory Effects in db/db Diabetic Mice","year":2022,"lang":"en","type":"article","venue":"Life","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Canada West","funders":"","keywords":"Autophagy; Trehalose; Endocrinology; Internal medicine; Inflammation; Spleen; Diabetes mellitus; Chemistry; Glycated hemoglobin; Biology; Type 2 diabetes; Medicine; Apoptosis; Biochemistry","score_opus":0.00731315609600472,"score_gpt":0.22741807140666204,"score_spread":0.22010491531065732,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221091910","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99304914,0.0054336665,0.0000032259954,0.0005894785,0.00019883073,0.00045714725,0.000008685627,0.000064932065,0.00019489939],"genre_scores_gemma":[0.9978447,0.00015490426,0.00003663231,0.0015462585,0.00015098193,0.00010972639,0.000013212292,0.00002864852,0.000114915],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989252,0.00015738311,0.00018808269,0.00027540993,0.00020891213,0.0002450159],"domain_scores_gemma":[0.9993048,0.00022790256,0.000053446776,0.00019274792,0.00001060733,0.00021050357],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016367277,0.00016268881,0.00037403547,0.00013086869,0.00014659329,0.00002403172,0.000057782592,0.000053447744,0.00009782703],"category_scores_gemma":[0.00010187383,0.00015421661,0.000056287554,0.00014296306,0.0001070516,0.00007314494,0.000089484056,0.0002278643,0.000009880231],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010375697,0.00090231403,0.8324764,0.001285305,0.0006297022,0.0015405618,0.0050864853,0.00003779568,0.13724421,0.0006848931,0.0016928832,0.017381934],"study_design_scores_gemma":[0.0045519024,0.00039817794,0.97625196,0.000082018545,0.00013310144,0.000034540873,0.00015617826,0.0007710218,0.015044142,0.0004783903,0.0018929923,0.00020559487],"about_ca_topic_score_codex":0.000047450627,"about_ca_topic_score_gemma":0.0000022080737,"teacher_disagreement_score":0.1437756,"about_ca_system_score_codex":0.00004420055,"about_ca_system_score_gemma":0.000116975025,"threshold_uncertainty_score":0.6288771},"labels":[],"label_agreement":null},{"id":"W4221130991","doi":"10.1152/ajpcell.00414.2021","title":"Free fatty acid treatment of mouse preimplantation embryos demonstrates contrasting effects of palmitic acid and oleic acid on autophagy","year":2022,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; Government of Canada; Children's Health Research Institute","keywords":"Autophagy; Blastocyst; Palmitic acid; Oleic acid; ATG5; Biology; Andrology; Embryo; Fatty acid; Lysosome; Internal medicine; Endocrinology; Embryogenesis; Cell biology; Biochemistry; Apoptosis; Medicine","score_opus":0.007048594766008697,"score_gpt":0.24690800378189404,"score_spread":0.23985940901588534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221130991","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973347,0.0018670368,0.000051558516,0.000065513865,0.00018053858,0.0003587947,0.000080027334,0.00001803203,0.00004374994],"genre_scores_gemma":[0.9985211,0.0005287205,0.00036897996,0.00030918545,0.0001468192,0.000037867838,0.00003929745,0.000031267544,0.000016745098],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979195,0.0005213148,0.0006815376,0.00031588404,0.00021558118,0.0003461606],"domain_scores_gemma":[0.99749005,0.00051479926,0.0013432849,0.00035634256,0.00013123883,0.00016431535],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011051281,0.0003032443,0.001313325,0.00022101968,0.000118022705,0.0000027656988,0.0002136313,0.000065434586,0.00007610066],"category_scores_gemma":[0.000068033834,0.00023841068,0.00028915252,0.00020547042,0.00068485906,0.000059785387,0.000061224215,0.0002916408,0.0000018581519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036897964,0.0014471835,0.0004545606,0.00018467351,0.0006174976,0.000050412287,0.00055333495,0.00024705776,0.9867491,0.00005013062,0.00004300139,0.005913236],"study_design_scores_gemma":[0.0055314396,0.027125183,0.08129145,0.000060498696,0.00036930066,0.00015473834,0.0006936173,0.00014744472,0.8837541,0.0007140218,0.00000892046,0.00014928223],"about_ca_topic_score_codex":0.000027944494,"about_ca_topic_score_gemma":5.3012934e-7,"teacher_disagreement_score":0.102995016,"about_ca_system_score_codex":0.000084323394,"about_ca_system_score_gemma":0.00019419502,"threshold_uncertainty_score":0.9722105},"labels":[],"label_agreement":null},{"id":"W4223948344","doi":"10.1038/s41419-022-04813-w","title":"Cancer cells adapt FAM134B/BiP mediated ER-phagy to survive hypoxic stress","year":2022,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Associazione Italiana per la Ricerca sul Cancro; Fondazione Telethon; University of South Australia; Deutsche Forschungsgemeinschaft; Department of Science and Technology, Ministry of Science and Technology, India; JSS College of Pharmacy; Australian Cancer Research Foundation; Fondazione Umberto Veronesi; Neurosurgical Research Foundation","keywords":"Cancer; Cancer research; Cancer cell; Cell biology; Biology; Chemistry; Genetics","score_opus":0.015088630086490556,"score_gpt":0.2614749669088657,"score_spread":0.24638633682237512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4223948344","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9812238,0.012802418,0.000044736767,0.0012326821,0.00039741592,0.0006729205,0.0015617958,0.000109470784,0.0019547374],"genre_scores_gemma":[0.9864695,0.0006307404,0.000030145027,0.008802218,0.00018951818,0.00029348198,0.0002697526,0.000042747906,0.0032719006],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99845713,0.000085862855,0.00020321835,0.00045170408,0.00040188414,0.00040018934],"domain_scores_gemma":[0.9975674,0.000075843454,0.000059106525,0.00036969173,0.000056272398,0.0018716735],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008175928,0.00023193168,0.0002844874,0.00012070714,0.00024858164,0.00002349259,0.00013873515,0.00003857813,0.0030075375],"category_scores_gemma":[0.0000341242,0.00021428632,0.00011685616,0.00023101394,0.000041474377,0.000051416144,0.00013225233,0.00016790217,0.00007614499],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.036881715,0.015566017,0.37925595,0.0033130057,0.001770787,0.019655798,0.008555768,0.0049445513,0.14836116,0.002568126,0.33958834,0.03953874],"study_design_scores_gemma":[0.025030207,0.0025098182,0.52876157,0.00030385546,0.0028967354,0.000023619406,0.0037728602,0.0057070944,0.08062598,0.0023442227,0.34509173,0.0029323252],"about_ca_topic_score_codex":0.00024400055,"about_ca_topic_score_gemma":0.000009443537,"teacher_disagreement_score":0.14950559,"about_ca_system_score_codex":0.000081345635,"about_ca_system_score_gemma":0.00044727852,"threshold_uncertainty_score":0.9979038},"labels":[],"label_agreement":null},{"id":"W4224236066","doi":"10.1016/j.bbadis.2022.166412","title":"The role of autophagy in the metabolism and differentiation of stem cells","year":2022,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"National Institute for Medical Research Development","keywords":"Autophagy; Stem cell; Cancer stem cell; Cell biology; Carcinogenesis; Biology; Cancer research; Cancer; Cancer cell; Senescence; Metastasis; Cellular differentiation; Apoptosis; Biochemistry; Genetics","score_opus":0.005758344587166126,"score_gpt":0.2294313044290427,"score_spread":0.22367295984187657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224236066","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99454355,0.003644328,0.000007350131,0.0008995127,0.000047370595,0.00054195133,0.00022931075,0.000011265567,0.00007534898],"genre_scores_gemma":[0.99919814,0.00029167417,0.000023825796,0.00030295493,0.00002084508,0.00007909099,0.00004372973,0.000024419336,0.000015303141],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99819624,0.0003852226,0.00040604032,0.0002550208,0.000573125,0.00018437141],"domain_scores_gemma":[0.99872607,0.00012516417,0.00033464664,0.0006432563,0.00006374851,0.00010708666],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002260506,0.00018314813,0.00035943819,0.00011337526,0.00009512317,0.0000125322895,0.0003359925,0.000033926124,0.000020322545],"category_scores_gemma":[0.00001737859,0.00012301601,0.00028724328,0.00033040482,0.00019970996,0.0000449042,0.00014634324,0.00015148676,5.1662016e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008848331,0.0010286325,0.00006543807,0.0000968314,0.00023004088,0.000007797456,0.0005861452,0.000009268717,0.992473,0.0030032732,0.00003769698,0.001577007],"study_design_scores_gemma":[0.0010449061,0.00016895159,0.08177787,0.000028977182,0.00045606538,8.028468e-7,0.00054012466,0.00029365395,0.9142126,0.0012653426,0.00010830758,0.000102440325],"about_ca_topic_score_codex":0.000026725062,"about_ca_topic_score_gemma":5.281244e-7,"teacher_disagreement_score":0.08171243,"about_ca_system_score_codex":0.000016005633,"about_ca_system_score_gemma":0.00014573405,"threshold_uncertainty_score":0.50164473},"labels":[],"label_agreement":null},{"id":"W4224243709","doi":"10.1083/jcb.202110151","title":"Secretory autophagy maintains proteostasis upon lysosome inhibition","year":2022,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":174,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of California, San Francisco; Mark Foundation For Cancer Research; Cancer Research Society; Samuel Waxman Cancer Research Foundation; National Institute on Aging; Damon Runyon Cancer Research Foundation; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Autophagy; Cell biology; Proteostasis; Autophagosome; Secretion; Lysosome; Biology; Secretory pathway; Autophagy-related protein 13; Signal transduction; Biochemistry; Endoplasmic reticulum; Apoptosis; Golgi apparatus","score_opus":0.012131017928213332,"score_gpt":0.2616758246906424,"score_spread":0.24954480676242904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224243709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948365,0.0021441914,0.00021182829,0.0009773104,0.0002932188,0.000255901,0.000015827267,0.000015546768,0.0012496755],"genre_scores_gemma":[0.99709284,0.0002952627,0.000092728544,0.0018106066,0.0003116643,0.000010829451,0.000014936393,0.000014498766,0.00035665487],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875575,0.00046005525,0.00033297736,0.00007945501,0.00017929544,0.00019246925],"domain_scores_gemma":[0.99920607,0.00009497044,0.00033826017,0.00018546869,0.00008243537,0.00009277994],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00080015033,0.000100372396,0.0002484595,0.00013244536,0.00018292364,0.000003346135,0.00014150287,0.00005293119,0.0018741419],"category_scores_gemma":[0.000025102245,0.000063118256,0.00015041542,0.00013570538,0.00007840644,0.000035790308,0.000068363785,0.00046409664,0.000018942159],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019904524,0.00029848717,0.00022326883,0.000029453986,0.00013929576,0.00022125884,0.0006654291,0.00009003279,0.9922729,0.00059699535,0.00076856016,0.0027038306],"study_design_scores_gemma":[0.004894341,0.0064163134,0.00672909,0.000035302946,0.00040715077,0.0021311287,0.0014935543,0.00013570905,0.92191803,0.009196065,0.046435088,0.00020821462],"about_ca_topic_score_codex":0.000008451771,"about_ca_topic_score_gemma":6.367233e-7,"teacher_disagreement_score":0.070354894,"about_ca_system_score_codex":0.0001447526,"about_ca_system_score_gemma":0.00022993445,"threshold_uncertainty_score":0.9990383},"labels":[],"label_agreement":null},{"id":"W4225013658","doi":"10.21203/rs.3.rs-1559637/v1","title":"Basal Gp78-dependent mitophagy promotes mitochondrial health and limits mitochondrial ROS","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; University of British Columbia","funders":"University of British Columbia; Canadian Institutes of Health Research; Western Canada Research Grid; Compute Canada; Faculty of Medicine, University of British Columbia","keywords":"Mitophagy; Mitochondrion; Cell biology; Mitochondrial ROS; Basal (medicine); Mitochondrial DNA; Reactive oxygen species; Chemistry; Biology; Autophagy; Endocrinology; Biochemistry; Apoptosis; Gene","score_opus":0.0718024808223435,"score_gpt":0.4197681696450102,"score_spread":0.34796568882266665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225013658","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9049861,0.05278874,0.00016004613,0.014355129,0.0068484466,0.015679002,0.00151996,0.00061208464,0.003050499],"genre_scores_gemma":[0.8924183,0.021896793,0.006050596,0.0036821445,0.028876591,0.008807919,0.0064118267,0.0010412858,0.030814514],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9906331,0.001605164,0.00087049307,0.0018208895,0.0034988443,0.0015715623],"domain_scores_gemma":[0.99524534,0.00054670137,0.00028053278,0.00172655,0.0005352102,0.0016656506],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010837223,0.00066587946,0.0012766864,0.0008160824,0.00085378496,0.0002820109,0.0006871396,0.0006165547,0.0029964505],"category_scores_gemma":[0.0009586503,0.0006244499,0.00047685287,0.00045169872,0.00038543352,0.00011432308,0.0018375353,0.0045595723,0.00012389537],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.06889556,0.023551734,0.035836298,0.059943117,0.009014812,0.01717601,0.039904207,0.0003182341,0.07109948,0.005583004,0.5194105,0.14926708],"study_design_scores_gemma":[0.11479665,0.073796794,0.10750352,0.024119185,0.0013361366,0.0013400534,0.023869492,0.00469815,0.07981358,0.07186403,0.4856101,0.011252302],"about_ca_topic_score_codex":0.00065341446,"about_ca_topic_score_gemma":0.0000472346,"teacher_disagreement_score":0.13801476,"about_ca_system_score_codex":0.00089885783,"about_ca_system_score_gemma":0.0050754673,"threshold_uncertainty_score":0.9996207},"labels":[],"label_agreement":null},{"id":"W4225139561","doi":"10.1007/s42977-022-00119-2","title":"Unlocking the gate to GABARAPL2","year":2022,"lang":"en","type":"review","venue":"Biologia Futura","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Autophagy; ULK1; Subfamily; Biology; ATG8; Intracellular; Computational biology; Cell biology; Genetics; Gene; Kinase; Protein kinase A; Apoptosis","score_opus":0.1585171307102266,"score_gpt":0.4165867062348279,"score_spread":0.2580695755246013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225139561","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00012276214,0.99508274,0.000004178092,0.0002604524,0.00095690956,0.0012504454,0.000060395912,0.00013223897,0.0021298828],"genre_scores_gemma":[0.000059976184,0.9949035,0.00003931009,0.0020128875,0.001112877,0.00039690052,0.00026471444,0.000044710443,0.0011651388],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99850696,0.00020689251,0.0003657537,0.0004102587,0.00018406814,0.00032604756],"domain_scores_gemma":[0.99873793,0.0002387674,0.00017028229,0.0007032322,0.000020535219,0.0001292557],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00028664258,0.0003522477,0.0010417397,0.000109330125,0.00021531913,0.000022950786,0.00042895778,0.0001958677,0.00245874],"category_scores_gemma":[0.00009757236,0.0001700012,0.0006118374,0.0004441115,0.00005606129,0.000012407372,0.00019788495,0.0005363108,0.00046651223],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023754661,0.00002881942,0.0000041275584,0.001043289,0.00027365988,0.00009865344,0.000040604948,1.7985322e-7,0.0000018275686,0.00024286374,0.0059505333,0.9922917],"study_design_scores_gemma":[0.00012335228,0.00019325905,0.000052940017,0.0010434034,0.0005117974,0.0001274213,0.000050043123,4.983734e-7,0.00000198682,0.000023362612,0.99766093,0.00021099996],"about_ca_topic_score_codex":0.0000072827534,"about_ca_topic_score_gemma":3.5795608e-7,"teacher_disagreement_score":0.9920807,"about_ca_system_score_codex":0.00013454992,"about_ca_system_score_gemma":0.0002578143,"threshold_uncertainty_score":0.99845314},"labels":[],"label_agreement":null},{"id":"W4225252336","doi":"10.1080/15548627.2022.2072657","title":"Targeting MCOLN1/TRPML1 channels to protect against ischemia-reperfusion injury by restoring the inhibited autophagic flux in cardiomyocytes","year":2022,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Key University Science Research Project of Jiangsu Province; National Natural Science Foundation of China","keywords":"Autophagy; Cell biology; Biology; Reactive oxygen species; Reperfusion injury; Mitochondrion; Cardioprotection; Flux (metallurgy); Ischemia; Apoptosis; Biochemistry; Chemistry; Internal medicine; Medicine","score_opus":0.009050193696981118,"score_gpt":0.2605300344372388,"score_spread":0.2514798407402577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225252336","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898431,0.0041954676,0.00004838114,0.0018080194,0.00065281446,0.0020623943,0.000044207176,0.0003001603,0.0010455019],"genre_scores_gemma":[0.9905632,0.00007038051,0.00014154943,0.0041596163,0.00044347747,0.0012808813,0.00013614295,0.000093044095,0.0031117217],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99680144,0.0002974103,0.0006104075,0.00071939296,0.0008351925,0.00073616876],"domain_scores_gemma":[0.9986342,0.00012161666,0.00016578902,0.0007450935,0.000076001925,0.00025727795],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011070243,0.00038648755,0.00055866904,0.0003268736,0.00063551875,0.00005205772,0.0004272421,0.00012655684,0.00061244227],"category_scores_gemma":[0.00025451757,0.00032022648,0.00021677076,0.0011374699,0.000070393064,0.000140632,0.0005161327,0.0008910797,0.00007963253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005516517,0.0003013852,0.00057702063,0.00006692164,0.00010324532,0.00036522743,0.002429499,0.0016235611,0.9642973,0.00006406335,0.019808091,0.009812046],"study_design_scores_gemma":[0.0022007355,0.0006010184,0.000802866,0.00014119163,0.000056081564,0.000041919233,0.0008151727,0.0023006164,0.9096213,0.00011662924,0.082809016,0.0004934603],"about_ca_topic_score_codex":0.0001596418,"about_ca_topic_score_gemma":0.000001135639,"teacher_disagreement_score":0.063000925,"about_ca_system_score_codex":0.00055715605,"about_ca_system_score_gemma":0.000251498,"threshold_uncertainty_score":0.99992496},"labels":[],"label_agreement":null},{"id":"W4225308829","doi":"10.1016/j.bcp.2022.115060","title":"A racemosin B derivative, C25, suppresses breast cancer growth via lysosomal membrane permeabilization and inhibition of autophagic flux","year":2022,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; China Scholarship Council; Guizhou Science and Technology Department; National Natural Science Foundation of China","keywords":"Autophagy; Cancer research; Breast cancer; Cancer cell; Programmed cell death; Biology; Cancer; Cell growth; Cell biology; Apoptosis; Biochemistry","score_opus":0.009580352997524829,"score_gpt":0.2851041916335144,"score_spread":0.27552383863598956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225308829","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99514765,0.0021706067,0.0000427201,0.0017664237,0.00019292448,0.00038022193,0.0001552201,0.000054143107,0.000090121976],"genre_scores_gemma":[0.9975112,0.0002317613,0.00006571571,0.001541391,0.00019190775,0.00017526513,0.00018433476,0.000021870383,0.00007656414],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989429,0.000120007804,0.00024736946,0.00029271195,0.0001966264,0.0002003958],"domain_scores_gemma":[0.9994972,0.000072354786,0.00010859952,0.000089060435,0.00010693924,0.00012585943],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007984245,0.00014559069,0.00028150616,0.00009133629,0.00010169059,0.0000033498934,0.00006189516,0.0000758708,0.0057102223],"category_scores_gemma":[0.000013286422,0.00014114447,0.00006510469,0.00022874551,0.00025552532,0.00006044862,0.000109304776,0.00018229478,0.0000025495021],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001212734,0.00055434206,0.0014826116,0.00019057261,0.00013011589,0.000030012003,0.00017182002,0.000011106322,0.9849655,0.00006363395,0.010868721,0.0003188112],"study_design_scores_gemma":[0.0033512232,0.00018738995,0.011014842,0.000016156951,0.0002303048,0.00014936752,0.0000500681,0.0009271851,0.98331374,0.00030595012,0.00032509153,0.00012869838],"about_ca_topic_score_codex":0.000028947941,"about_ca_topic_score_gemma":1.0322434e-7,"teacher_disagreement_score":0.0105436295,"about_ca_system_score_codex":0.00009309352,"about_ca_system_score_gemma":0.00011429302,"threshold_uncertainty_score":0.99519867},"labels":[],"label_agreement":null},{"id":"W4225368765","doi":"10.1096/fasebj.2022.36.s1.r5201","title":"The Autophagic Response to Acute Exercise in Young Men is Exercise Intensity Dependent and Influenced by Exposure to Heat","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Exercise intensity; Heat stress; Analysis of variance; Medicine; Endocrinology; Internal medicine; Chemistry; Biology; Heart rate; Biochemistry; Animal science","score_opus":0.008008587232151254,"score_gpt":0.2624986069219739,"score_spread":0.25449001968982266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225368765","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9850713,0.0034405072,0.00002113738,0.010381665,0.00022610671,0.0007211392,0.000042881406,0.000024705922,0.00007056733],"genre_scores_gemma":[0.9929448,0.0009920885,0.00003589764,0.0033200467,0.00005129553,0.00009034999,0.0000026962969,0.000024502233,0.002538318],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99813676,0.0002631381,0.00035345572,0.00023939487,0.0006060139,0.00040123644],"domain_scores_gemma":[0.99886894,0.00010490927,0.00006877033,0.0004561515,0.00008842982,0.00041279453],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001658882,0.0001913265,0.00031685288,0.0001432407,0.0008800894,0.000100350764,0.00037850137,0.000041039584,0.0002534382],"category_scores_gemma":[0.00006448228,0.000115065406,0.000094319155,0.00033084152,0.000065860004,0.00008592583,0.00028244543,0.00065477623,0.00002682711],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.08138632,0.00039965543,0.015516456,0.000017823733,0.00036698513,0.0021693755,0.03548545,0.0004251589,0.81039804,0.000013768728,0.038139764,0.015681189],"study_design_scores_gemma":[0.015264554,0.0046717497,0.5308038,0.00087368325,0.001125731,0.0073318603,0.028023772,0.0007544542,0.403093,0.0017253591,0.0052489783,0.0010830126],"about_ca_topic_score_codex":0.00008860218,"about_ca_topic_score_gemma":0.000006990963,"teacher_disagreement_score":0.51528734,"about_ca_system_score_codex":0.00023465797,"about_ca_system_score_gemma":0.00015952782,"threshold_uncertainty_score":0.67690253},"labels":[],"label_agreement":null},{"id":"W4225379890","doi":"10.1096/fasebj.2022.36.s1.r4805","title":"MYTHO: A novel regulator of autophagy and skeletal muscle health","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; Children's Hospital of Eastern Ontario; University of Ottawa; McGill University Health Centre; Christie (Canada)","funders":"Canadian Institutes of Health Research","keywords":"Regulator; Autophagy; Skeletal muscle; Cell biology; Chemistry; Physical medicine and rehabilitation; Medicine; Biology; Internal medicine; Biochemistry","score_opus":0.017900545555410177,"score_gpt":0.27994011161270954,"score_spread":0.2620395660572994,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225379890","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918305,0.0041843,0.00024611183,0.0031240177,0.00018107104,0.00015147036,0.000029620003,0.00001565163,0.00023720514],"genre_scores_gemma":[0.996835,0.0001510728,0.00028625366,0.0019236219,0.00019426964,0.0000053849167,0.0000039299066,0.0000149872585,0.00058551563],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99904364,0.0000939344,0.0002477837,0.000094012496,0.00033361363,0.00018703805],"domain_scores_gemma":[0.9993648,0.00003828157,0.00019421516,0.00019502213,0.000032370997,0.00017531493],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00059734425,0.00008230619,0.00021172466,0.0000656537,0.0003922106,0.000010267774,0.0001092342,0.000016164933,0.000680239],"category_scores_gemma":[0.000017371663,0.00005536484,0.00010431417,0.000121469,0.00009278334,0.000038140908,0.000065460525,0.0003418556,0.0000021124797],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012091987,0.002081066,0.002433281,0.00023055267,0.0009662276,0.000418701,0.010909292,0.00025059207,0.812257,0.008295673,0.011572077,0.14937635],"study_design_scores_gemma":[0.026953105,0.008438585,0.7498468,0.00034880498,0.0006145735,0.02445607,0.01063359,0.004610286,0.091071025,0.007923488,0.07435389,0.0007497872],"about_ca_topic_score_codex":0.000017155153,"about_ca_topic_score_gemma":5.299964e-7,"teacher_disagreement_score":0.7474135,"about_ca_system_score_codex":0.00006275726,"about_ca_system_score_gemma":0.0003011128,"threshold_uncertainty_score":0.74481404},"labels":[],"label_agreement":null},{"id":"W4225379937","doi":"10.1096/fasebj.2022.36.s1.r2177","title":"The Effect of Increasing Levels of Hyperthermia on Autophagy in Peripheral Blood Mononuclear Cells from Young Adults","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Peripheral blood mononuclear cell; Autophagy; Peripheral blood; Peripheral; Hyperthermia; Medicine; Immunology; Chemistry; Internal medicine; Apoptosis; In vitro; Biochemistry","score_opus":0.007638773129088251,"score_gpt":0.2351478813381322,"score_spread":0.22750910820904394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225379937","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99727637,0.0015826776,0.0000031845022,0.00014032914,0.0002389631,0.00025455473,0.000049147457,0.000010180082,0.00044459087],"genre_scores_gemma":[0.99940425,0.00011125265,0.000029338009,0.00014167557,0.00017008324,0.000007878755,0.0000023693344,0.000027650278,0.00010547251],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980024,0.0008050442,0.0003818755,0.00012294976,0.00046671618,0.00022103064],"domain_scores_gemma":[0.9987688,0.0005356843,0.00026453874,0.0003197128,0.0000316874,0.00007958546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010624478,0.0001439708,0.00032891514,0.000067520516,0.0003205995,0.000015968259,0.00030511493,0.000036872596,0.00068917876],"category_scores_gemma":[0.00006634095,0.00007811034,0.00020005828,0.0001525104,0.00010863874,0.000038277456,0.000064014814,0.0005963797,0.0000037100083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01394967,0.00036890086,0.020466411,0.000029507319,0.0005318193,0.0003919325,0.0039059941,0.0010723997,0.9354002,0.00003917387,0.00007402337,0.023769958],"study_design_scores_gemma":[0.008749931,0.0031903617,0.18041664,0.00025465275,0.00027589584,0.00042633587,0.0012093859,0.0015481097,0.8034682,0.00025918646,0.000070360846,0.00013090648],"about_ca_topic_score_codex":0.00030072563,"about_ca_topic_score_gemma":0.00000755264,"teacher_disagreement_score":0.15995023,"about_ca_system_score_codex":0.00007450046,"about_ca_system_score_gemma":0.00009685719,"threshold_uncertainty_score":0.75460243},"labels":[],"label_agreement":null},{"id":"W4225392375","doi":"10.1096/fasebj.2022.36.s1.r4019","title":"Role of TFE3 in Mitochondrial Adaptations to Skeletal Muscle Disuse","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Denervation; Skeletal muscle; Mitochondrion; Autophagy; Sarcopenia; Muscle atrophy; Biology; Mitophagy; Endocrinology; TFEB; Internal medicine; Atrophy; Oxidative stress; Oxidative phosphorylation; Cell biology; Biochemistry; Medicine; Apoptosis","score_opus":0.013388446741507217,"score_gpt":0.26859078171568895,"score_spread":0.2552023349741817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225392375","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99708754,0.0005030376,0.00009373244,0.0011949221,0.00023102049,0.00018853656,0.000022869106,0.00000807144,0.00067030184],"genre_scores_gemma":[0.9987101,0.000024308942,0.00019002605,0.00042160117,0.0002885761,0.000021442602,0.0000056894046,0.000011161562,0.00032712272],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999166,0.00010425034,0.00021159896,0.00007258962,0.00029948654,0.00014606636],"domain_scores_gemma":[0.99956954,0.00004885761,0.000073077856,0.00016576383,0.000031141113,0.00011163816],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018069129,0.00006206698,0.00012917965,0.0001114198,0.00017815102,0.000008527207,0.00014796143,0.0000136728595,0.0013056935],"category_scores_gemma":[0.00003991565,0.000044507007,0.00010600961,0.00022698595,0.000032841424,0.00003959083,0.00004713424,0.00030889286,0.00001535985],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00059550506,0.00053423055,0.0014714968,0.00000470717,0.00009242056,0.00012355151,0.005257306,0.0017803403,0.97109663,0.00080809894,0.0010253927,0.017210288],"study_design_scores_gemma":[0.016368382,0.003615507,0.74624974,0.00017054222,0.00048569732,0.0014355165,0.03444633,0.0024507705,0.13444662,0.015430621,0.044322878,0.00057743397],"about_ca_topic_score_codex":0.000032192467,"about_ca_topic_score_gemma":0.00001134222,"teacher_disagreement_score":0.8366501,"about_ca_system_score_codex":0.00006141683,"about_ca_system_score_gemma":0.00014597514,"threshold_uncertainty_score":0.99960726},"labels":[],"label_agreement":null},{"id":"W4225396305","doi":"10.1096/fasebj.2022.36.s1.r6287","title":"Essential role for epithelial HIF‐xenophagy axis in control of <i>Salmonella</i> infection and dissemination","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"","keywords":"Cell biology; Autophagy; Biology; Intracellular; Intestinal epithelium; Hypoxia-inducible factors; Innate immune system; Salmonella enterica; Epithelium; Immune system; Salmonella; Immunology; Apoptosis; Biochemistry; Gene; Bacteria","score_opus":0.005472259204979194,"score_gpt":0.2604742850294483,"score_spread":0.2550020258244691,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225396305","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99606436,0.0011530912,0.0016668619,0.00045808413,0.00019813192,0.0003104612,0.000043927186,0.0000074445325,0.00009761724],"genre_scores_gemma":[0.99923956,0.00015770983,0.000021649612,0.00014280209,0.00025086317,0.000030463261,0.000008905265,0.000011474142,0.00013653896],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928784,0.00009743309,0.00021991556,0.00008019012,0.0001917701,0.00012282754],"domain_scores_gemma":[0.9995366,0.00013318827,0.00014412047,0.00008524473,0.000047733836,0.00005315471],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005030571,0.00006964363,0.00016324299,0.00009353839,0.00020716822,0.000010977347,0.000052147374,0.000023874125,0.00018563902],"category_scores_gemma":[0.000049070582,0.00005111454,0.00008291826,0.00010641262,0.000045756078,0.000052435083,0.000017696655,0.00020130993,7.220908e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030117908,0.0003717395,0.01403344,0.000031194075,0.00013056563,0.00002943597,0.0011270964,0.0003599576,0.96549547,0.0003285142,0.00021861028,0.014862182],"study_design_scores_gemma":[0.014699668,0.002406,0.13515595,0.00012463178,0.0005256146,0.0011419138,0.0012385143,0.010712685,0.8231181,0.0093551325,0.0012815087,0.00024030166],"about_ca_topic_score_codex":0.000028222414,"about_ca_topic_score_gemma":0.0000031329616,"teacher_disagreement_score":0.14237739,"about_ca_system_score_codex":0.00004891838,"about_ca_system_score_gemma":0.000055517135,"threshold_uncertainty_score":0.20843905},"labels":[],"label_agreement":null},{"id":"W4225411390","doi":"10.1096/fasebj.2022.36.s1.0r555","title":"Age‐Associated Changes in Autophagy in Peripheral Blood Mononuclear Cells following Maximal Exercise: Preliminary Observations","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Context (archaeology); Peripheral blood mononuclear cell; Neurodegeneration; Medicine; Peripheral; Biology; Cell biology; Disease; Internal medicine; Apoptosis; In vitro; Biochemistry","score_opus":0.02481063280240357,"score_gpt":0.25550487811473815,"score_spread":0.2306942453123346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225411390","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956152,0.0019031757,0.000004530087,0.0014622804,0.00033538422,0.00036897376,0.00001564895,0.000040285064,0.00025454845],"genre_scores_gemma":[0.99678963,0.00027159715,0.00012434041,0.0009901386,0.00012951423,0.00006481343,0.000022436554,0.000039702947,0.0015677959],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99839556,0.00025517592,0.0003334617,0.00017757309,0.00043076812,0.00040747537],"domain_scores_gemma":[0.9994279,0.00006523191,0.00013932995,0.0002227055,0.000023551107,0.00012127588],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00071159995,0.00016492684,0.00032176098,0.00019840727,0.00042714312,0.000042700467,0.00027402915,0.000059678576,0.000939977],"category_scores_gemma":[0.000032888933,0.00013579098,0.00018448466,0.00048357924,0.00003958004,0.00010828731,0.00010979185,0.00088962924,0.000006347911],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005430989,0.0073188646,0.08028877,0.00008867255,0.0012135727,0.042710043,0.040679965,0.011500904,0.7952377,0.000213784,0.0037321667,0.011584539],"study_design_scores_gemma":[0.018871225,0.0028426684,0.903996,0.0006436559,0.000863672,0.0008492567,0.010174646,0.0076293554,0.050368693,0.002181532,0.0008923727,0.00068691775],"about_ca_topic_score_codex":0.00006629188,"about_ca_topic_score_gemma":0.000032540913,"teacher_disagreement_score":0.8237072,"about_ca_system_score_codex":0.00025293016,"about_ca_system_score_gemma":0.0001738448,"threshold_uncertainty_score":0.9999733},"labels":[],"label_agreement":null},{"id":"W4226094138","doi":"10.1080/15548627.2022.2039994","title":"Autophagopathies: from autophagy gene polymorphisms to precision medicine for human diseases","year":2022,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Institute of General Medical Sciences; Canceropôle Provence-Alpes-Côte d’Azur; National Institutes of Health; Agence Nationale de la Recherche","keywords":"Autophagy; Biology; Single-nucleotide polymorphism; SNP; Etiology; Gene; Bioinformatics; Genetics; Microbiome; Immunology; Medicine; Genotype; Internal medicine","score_opus":0.024037930653689192,"score_gpt":0.31961154674399916,"score_spread":0.29557361609030997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226094138","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9761979,0.009853279,0.0033469032,0.0029328042,0.0018418352,0.0027017368,0.0014111603,0.00081230165,0.0009020947],"genre_scores_gemma":[0.97598624,0.000050845574,0.0017052783,0.00988503,0.0017217881,0.0016894288,0.0015104169,0.0001772053,0.007273737],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99574256,0.00019010705,0.0009022775,0.0011875961,0.0011432363,0.00083421584],"domain_scores_gemma":[0.9969422,0.00040577803,0.000266879,0.0013389097,0.00016791743,0.0008783052],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00041090528,0.0005752704,0.001070328,0.000508207,0.001072877,0.00003982001,0.0006637853,0.00014184653,0.010075957],"category_scores_gemma":[0.00025116987,0.000528771,0.0004572986,0.0006904131,0.00017922554,0.00015241135,0.00040526362,0.00037318177,0.00014911545],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0058604097,0.0038329547,0.002595531,0.0001732204,0.0014429451,0.0019868738,0.005892326,0.0005714838,0.79094404,0.0152487,0.08853692,0.08291462],"study_design_scores_gemma":[0.02789483,0.013399223,0.31885377,0.00035858888,0.002195944,0.00030295845,0.00090537185,0.0026204553,0.2980218,0.05867234,0.2744795,0.0022951935],"about_ca_topic_score_codex":0.00041343388,"about_ca_topic_score_gemma":0.0000060179564,"teacher_disagreement_score":0.49292222,"about_ca_system_score_codex":0.00040322487,"about_ca_system_score_gemma":0.00031347398,"threshold_uncertainty_score":0.9997164},"labels":[],"label_agreement":null},{"id":"W4226243460","doi":"10.1007/s00109-022-02191-6","title":"The role of the individual TOM subunits in the association of PINK1 with depolarized mitochondria","year":2022,"lang":"en","type":"article","venue":"Journal of Molecular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Eberhard Karls Universität Tübingen; Deutsche Forschungsgemeinschaft","keywords":"PINK1; Mitophagy; Mitochondrion; Cell biology; Organelle; Biology; Chemistry; Biochemistry; Autophagy","score_opus":0.006433402828622905,"score_gpt":0.2373186860357655,"score_spread":0.2308852832071426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226243460","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98322,0.007164862,0.00005032089,0.008625589,0.00017399562,0.00029645325,0.0000052177966,0.0000019675856,0.00046160628],"genre_scores_gemma":[0.9983517,0.000116284,0.00004080398,0.0013074437,0.000113533664,0.000007442196,0.0000033145145,0.000011058768,0.00004839703],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9972475,0.00052080624,0.000508194,0.000064575994,0.0015213429,0.00013757769],"domain_scores_gemma":[0.99827397,0.00030156694,0.0008982617,0.0002747479,0.0002062508,0.00004519831],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015163842,0.00009094745,0.00031476357,0.0000988155,0.000106626736,0.0000045620245,0.0004091086,0.000038328875,0.00004449552],"category_scores_gemma":[0.0004497995,0.000036903995,0.00012346059,0.0005026821,0.00010489029,0.00002760949,0.00004397468,0.0005643763,1.5482429e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004948699,0.0012107973,0.23535621,0.0000788904,0.002586703,0.0005491681,0.01648767,0.00025392172,0.7221899,0.0026827266,0.0028262096,0.010829132],"study_design_scores_gemma":[0.02604291,0.006662596,0.7968669,0.0008042345,0.002639314,0.0011176775,0.02992449,0.00014167423,0.103613384,0.005276848,0.026695928,0.00021401992],"about_ca_topic_score_codex":0.000040581726,"about_ca_topic_score_gemma":0.000013395945,"teacher_disagreement_score":0.61857647,"about_ca_system_score_codex":0.00007206732,"about_ca_system_score_gemma":0.0002751139,"threshold_uncertainty_score":0.24519657},"labels":[],"label_agreement":null},{"id":"W4228996597","doi":"10.1139/bcb-2021-0144","title":"CD142 plays a key role in the carcinogenesis of gastric adenocarcinoma by inhibiting <i>BCL2</i>-dependent autophagy","year":2021,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autophagy; Gene silencing; Carcinogenesis; Cancer research; Metastasis; Cancer; Downregulation and upregulation; Cancer cell; Chemistry; Pathogenesis; Apoptosis; Biology; Immunology; Gene; Biochemistry","score_opus":0.0072729976595659425,"score_gpt":0.22402348921673532,"score_spread":0.21675049155716938,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4228996597","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95354456,0.042319957,0.000010415664,0.00014108443,0.000025543253,0.00009546304,0.00006137538,0.0000113227425,0.003790275],"genre_scores_gemma":[0.99825794,0.000620046,0.000042261185,0.00047186034,0.00009385051,0.000019104937,0.00015689671,0.000009621413,0.00032844444],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990135,0.00007852169,0.00025761695,0.00031685113,0.0000934624,0.00024004685],"domain_scores_gemma":[0.9994745,0.0000793264,0.0000881999,0.00023454102,0.000043274074,0.00008014011],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014206876,0.00014738827,0.00027062293,0.000027961236,0.00004755485,0.000006725223,0.00010046083,0.00018996,0.00011076494],"category_scores_gemma":[0.000031883406,0.00011276211,0.000076458215,0.00016103414,0.000106172694,0.000012211151,0.000055418805,0.00015695767,0.0000030065976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008110782,0.00021495041,0.036845442,0.00012097916,0.000027254217,0.00011416301,0.00020767255,4.888339e-7,0.96125025,0.00003224079,0.00011814252,0.0009873075],"study_design_scores_gemma":[0.0011755782,0.00011484753,0.008714349,0.000027772632,0.00005912559,0.00017080767,0.0010956351,0.0000201428,0.9880334,0.00009567557,0.0003930947,0.00009954246],"about_ca_topic_score_codex":0.000040031242,"about_ca_topic_score_gemma":0.0000013328286,"teacher_disagreement_score":0.044713352,"about_ca_system_score_codex":0.000019100384,"about_ca_system_score_gemma":0.000132607,"threshold_uncertainty_score":0.45983055},"labels":[],"label_agreement":null},{"id":"W4229024039","doi":"10.1083/jcb.202105112","title":"V-ATPase is a universal regulator of LC3-associated phagocytosis and non-canonical autophagy","year":2022,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":171,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; Cancer Research UK","keywords":"Autophagy; ATG16L1; Cell biology; Regulator; Endocytosis; Lysosome; Biology; Chemistry; Phagocytosis; Biochemistry; Enzyme; Receptor; Gene","score_opus":0.008927924726136604,"score_gpt":0.25214535668277654,"score_spread":0.24321743195663995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4229024039","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99621123,0.0021428533,0.000023285545,0.00074886065,0.0001422181,0.000099807105,0.000029380888,0.0000056343943,0.00059674116],"genre_scores_gemma":[0.99798703,0.00048058658,0.000046183293,0.00093387865,0.00007203256,0.0000010287745,0.00000382739,0.000010938053,0.00046451142],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990049,0.0002585243,0.0003356296,0.00008244446,0.0001575255,0.00016095761],"domain_scores_gemma":[0.9990229,0.00018493971,0.0004216418,0.00016416577,0.00009915579,0.00010720324],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053598895,0.00009586601,0.00037839095,0.00009763392,0.00010019755,0.0000018969646,0.00017423587,0.000068259156,0.0008421404],"category_scores_gemma":[0.000030275913,0.00006288206,0.00013785875,0.00014822166,0.00018812412,0.000025272591,0.00008744238,0.0003025445,0.0000021319756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037545615,0.0006939501,0.0026460213,0.00002928441,0.000672297,0.0001403872,0.0017462722,0.000019818892,0.9863074,0.00020205083,0.0022634212,0.0015245578],"study_design_scores_gemma":[0.015700359,0.009826672,0.05327322,0.00005925895,0.0014844456,0.00067836413,0.0018144627,0.0006271555,0.90116304,0.001914955,0.013193731,0.00026433807],"about_ca_topic_score_codex":0.00002620132,"about_ca_topic_score_gemma":8.6037306e-7,"teacher_disagreement_score":0.08514434,"about_ca_system_score_codex":0.00008372682,"about_ca_system_score_gemma":0.00031198596,"threshold_uncertainty_score":0.9220847},"labels":[],"label_agreement":null},{"id":"W4229042404","doi":"10.1016/j.bbadis.2022.166431","title":"Autophagy and EMT in cancer and metastasis: Who controls whom?","year":2022,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":155,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"","keywords":"Autophagy; Metastasis; Cancer research; Epithelial–mesenchymal transition; Cancer; Angiogenesis; Tumor microenvironment; Biology; Cancer cell; Apoptosis; Medicine; Tumor cells","score_opus":0.032939164155092335,"score_gpt":0.3482559602805609,"score_spread":0.31531679612546853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4229042404","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2463547,0.7500549,0.0000020264297,0.000486622,0.000068143134,0.0015370969,0.0013866177,0.000046697285,0.00006319601],"genre_scores_gemma":[0.08143814,0.9159422,0.00006232476,0.0009528102,0.00008955614,0.00080858544,0.00047629533,0.00016129646,0.00006876756],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.996259,0.0004996491,0.00093414256,0.0011381618,0.0006442842,0.00052476977],"domain_scores_gemma":[0.9973651,0.00019608975,0.00063414,0.0010061144,0.000062401225,0.00073614024],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002446459,0.0008906108,0.0029757451,0.000538433,0.00011538886,0.00008014784,0.00036260238,0.00022723929,0.0002007749],"category_scores_gemma":[0.00012713081,0.0007819719,0.0010012205,0.00062138436,0.0004166621,0.00012194778,0.00033968777,0.00056095695,0.0000037091693],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003111659,0.0055648778,0.00002715062,0.071674876,0.01160578,0.0020741292,0.0005978323,0.000002640319,0.022117885,0.0019841576,0.0010888047,0.8801502],"study_design_scores_gemma":[0.023772912,0.0030326627,0.012543896,0.05055423,0.078978345,0.00011159398,0.0003036492,0.00023620263,0.058753833,0.0016152287,0.76314646,0.0069509903],"about_ca_topic_score_codex":0.00007912702,"about_ca_topic_score_gemma":0.0000025518054,"teacher_disagreement_score":0.8731992,"about_ca_system_score_codex":0.00012843311,"about_ca_system_score_gemma":0.0012821035,"threshold_uncertainty_score":0.99946314},"labels":[],"label_agreement":null},{"id":"W4229365822","doi":"10.31083/j.rcm2305167","title":"Importance of Autophagy in Mediating Cellular Responses to Iron Overload in Cardiomyocytes","year":2022,"lang":"en","type":"review","venue":"Reviews in Cardiovascular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research; International Development Research Centre; Thalassemia Foundation of Canada","keywords":"Autophagy; Crosstalk; Endoplasmic reticulum; Medicine; Cardiomyopathy; Cell biology; Unfolded protein response; Oxidative stress; Heart failure; Mitochondrion; Biology; Internal medicine; Biochemistry; Apoptosis","score_opus":0.06965759676037825,"score_gpt":0.36396971815576756,"score_spread":0.2943121213953893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4229365822","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017928996,0.99124146,0.000013469669,0.000053248445,0.0004980622,0.0055114324,0.00003284991,0.00003413837,0.00082243746],"genre_scores_gemma":[0.00037731064,0.99644804,0.00019860663,0.00028779684,0.0005632884,0.0016357242,0.00024139573,0.00014410124,0.00010372192],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.98982924,0.0027816226,0.0038097994,0.0012852384,0.0015442979,0.0007497792],"domain_scores_gemma":[0.9955044,0.0008204996,0.00075746997,0.002557603,0.00005064025,0.00030939907],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0107698245,0.0009353977,0.012741207,0.0020355445,0.00003665949,0.000005122392,0.000620768,0.0003662875,0.00048471108],"category_scores_gemma":[0.0037476588,0.00073686923,0.003121621,0.0036354288,0.00015471442,0.000075945674,0.00025304404,0.0013983084,0.000029313045],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009393724,0.0001505592,0.0010465297,0.04566633,0.00065540825,0.0036279173,0.0004928078,0.00002740098,0.000014375042,0.00001948496,0.00015200084,0.94805324],"study_design_scores_gemma":[0.0022247469,0.0002632509,0.0013743604,0.060068436,0.0022328258,0.0001594253,0.000093349896,0.0000047699064,0.000017998173,0.0000152182865,0.9330411,0.00050449505],"about_ca_topic_score_codex":0.0003375097,"about_ca_topic_score_gemma":0.000032365017,"teacher_disagreement_score":0.94754875,"about_ca_system_score_codex":0.001234839,"about_ca_system_score_gemma":0.00077727577,"threshold_uncertainty_score":0.99950826},"labels":[],"label_agreement":null},{"id":"W4229454389","doi":"10.15252/embj.2021110031","title":"The multifaceted role of autophagy in cancer","year":2022,"lang":"en","type":"review","venue":"The EMBO Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":225,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Basic Research Laboratory; National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Autophagy; Biology; Cell biology; Carcinogenesis; Organelle; Cancer cell; Intracellular; Cancer; Biochemistry; Genetics; Apoptosis","score_opus":0.0594204241695464,"score_gpt":0.39724350161779143,"score_spread":0.337823077448245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4229454389","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012038259,0.99670225,6.740861e-7,0.00015809263,0.00046349448,0.00047708603,0.000019244488,0.000010447748,0.000964878],"genre_scores_gemma":[0.00023231878,0.99779814,0.0000068829295,0.000110445966,0.0004377729,0.00009480546,0.000006646976,0.000041789215,0.001271192],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99809706,0.000437478,0.00065245765,0.00012730864,0.00041383028,0.0002718689],"domain_scores_gemma":[0.99852943,0.00036548183,0.000561826,0.0004141845,0.000037394228,0.00009170069],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00086180214,0.00021863957,0.00093122426,0.00011147144,0.0002782145,0.000022585526,0.00051054626,0.00007755859,0.0024787555],"category_scores_gemma":[0.00007582785,0.00009675908,0.0005536556,0.00031913133,0.000100884296,0.00002548738,0.00008116057,0.0013632899,0.000015648762],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054295204,0.00007674258,0.0000066060193,0.00045527273,0.00043201723,0.0000756394,0.00030903262,0.0000058010232,0.000004341188,0.00007786558,0.0004825831,0.9980198],"study_design_scores_gemma":[0.0005279319,0.000070909315,0.000095823045,0.002374465,0.00066231465,0.0004981468,0.00022059839,0.00003501205,0.000014789987,0.00038438843,0.9950225,0.00009314499],"about_ca_topic_score_codex":0.000049415183,"about_ca_topic_score_gemma":0.000007735781,"teacher_disagreement_score":0.99792665,"about_ca_system_score_codex":0.00022490621,"about_ca_system_score_gemma":0.0009746916,"threshold_uncertainty_score":0.9984331},"labels":[],"label_agreement":null},{"id":"W4232523737","doi":"10.1101/2020.11.12.380709","title":"ORF3a mediated-incomplete autophagy facilitates SARS-CoV-2 replication","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Shanghai Jiao Tong University; Program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning; National Natural Science Foundation of China; Shandong University","keywords":"Autophagy; Autophagosome; Cell biology; Viral replication; Biology; ULK1; ATG16L1; Virology; Chemistry; Virus; Genetics; Phosphorylation; Apoptosis","score_opus":0.037989298825857415,"score_gpt":0.28044692285951206,"score_spread":0.24245762403365465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4232523737","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9872245,0.003472137,0.0013223743,0.0026906629,0.0008685238,0.0017310358,0.00071846595,0.0019053703,0.00006690259],"genre_scores_gemma":[0.99123734,0.00061087636,0.002857375,0.003777884,0.00083546335,0.00043646418,0.000010254149,0.00022395028,0.000010370589],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9955642,0.00017058237,0.0009279026,0.0019335926,0.0007133095,0.00069036527],"domain_scores_gemma":[0.9951514,0.00012490827,0.00055428356,0.003085938,0.00058569637,0.0004977808],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004901186,0.0008383367,0.0011645105,0.00030267835,0.00017298,0.00013648838,0.0006456725,0.0007371755,0.000117617754],"category_scores_gemma":[0.0007475424,0.00085904595,0.00042338547,0.000623143,0.00021160927,0.0001459,0.0004528661,0.0011579598,0.0009462437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019561504,0.00023795043,0.0015492949,0.00087261637,0.0005837534,0.00029785794,0.000034904922,0.0000035327457,0.9928313,0.00061925733,0.00276689,0.0000070323317],"study_design_scores_gemma":[0.001507495,0.00018962548,0.10387765,0.0004319257,0.0004363746,8.917833e-8,0.0000034613686,0.0013649941,0.8592344,0.000032694195,0.03201493,0.0009063626],"about_ca_topic_score_codex":0.00006164389,"about_ca_topic_score_gemma":8.137826e-7,"teacher_disagreement_score":0.13359688,"about_ca_system_score_codex":0.00038019128,"about_ca_system_score_gemma":0.0010806664,"threshold_uncertainty_score":0.9998316},"labels":[],"label_agreement":null},{"id":"W4234911618","doi":"10.3410/f.718245186.793492308","title":"Faculty Opinions recommendation of Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control.","year":2014,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McGill University","keywords":"Mitophagy; Parkin; PINK1; Mitochondrion; Autophagy; Cell biology; Biogenesis; Biology; Mitochondrial biogenesis; Population; Genetics; Gene; Parkinson's disease; Medicine; Disease; Internal medicine","score_opus":0.02806491529560445,"score_gpt":0.35088668648293797,"score_spread":0.3228217711873335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4234911618","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000030267494,0.0020715138,0.0002015075,0.061730232,0.00089896494,0.0019272609,0.9330793,0.000039021998,0.000021901667],"genre_scores_gemma":[0.0005236519,0.00021327696,0.00034961232,0.0045593306,0.0006021799,0.00023660716,0.9933608,0.000028944323,0.00012559934],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99474365,0.00095707725,0.0020064411,0.0007137381,0.0012429486,0.00033616854],"domain_scores_gemma":[0.9940468,0.00028751817,0.0017487481,0.0011587093,0.002460212,0.00029800867],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0019703177,0.00049989065,0.0013902269,0.0003698579,0.00016962648,0.00007577241,0.00048429694,0.0007802749,0.00016697422],"category_scores_gemma":[0.006593313,0.00033696293,0.00057813356,0.0012049361,0.00029159748,0.00022897556,0.00014645522,0.0010107901,0.0000072681637],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017276475,0.0004734195,0.000027645245,0.0074826013,0.00023348648,5.19682e-7,0.00010791812,4.3910293e-7,0.000024995908,0.00027332306,0.9845628,0.0066400883],"study_design_scores_gemma":[0.003774181,0.00025407973,0.011552477,0.015207453,0.00034792014,0.000026392116,0.000028096592,0.00005459066,0.000025549843,0.00005068118,0.9683912,0.0002874265],"about_ca_topic_score_codex":0.00006021052,"about_ca_topic_score_gemma":0.000008540457,"teacher_disagreement_score":0.060281467,"about_ca_system_score_codex":0.00011547431,"about_ca_system_score_gemma":0.0004538439,"threshold_uncertainty_score":0.99990827},"labels":[],"label_agreement":null},{"id":"W4238568709","doi":"10.3410/f.737795659.793574735","title":"Faculty Opinions recommendation of Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I.","year":2020,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; University of California, San Francisco; York University; Stand Up To Cancer; Lustgarten Foundation; Damon Runyon Cancer Research Foundation; Uehara Memorial Foundation; Pancreatic Cancer Action Network; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"KRAS; Autophagy; Evasion (ethics); Pancreatic cancer; Immune system; Cancer research; Cancer; Biology; Immunology; Genetics; Colorectal cancer; Apoptosis","score_opus":0.034185288459848015,"score_gpt":0.3683641531737188,"score_spread":0.33417886471387076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4238568709","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000127037365,0.010453926,0.000022383389,0.11605788,0.00052735733,0.0019435588,0.87091345,0.000043632666,0.000025113428],"genre_scores_gemma":[0.000113542745,0.0031002692,0.00037650776,0.0032553177,0.0002583304,0.00033933972,0.9919138,0.00004303263,0.00059985387],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9949756,0.00040566147,0.002079538,0.00066222367,0.0015316244,0.00034530714],"domain_scores_gemma":[0.9920845,0.00016168726,0.0022420892,0.0013061223,0.0038138179,0.00039176363],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00081819494,0.00058352645,0.0017067622,0.000297854,0.0001618493,0.000044918343,0.0010319958,0.0006651117,0.00083106395],"category_scores_gemma":[0.004324714,0.00037275522,0.00090080925,0.0019984902,0.00036971387,0.00023612077,0.0002933642,0.00097211497,0.000027980655],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006672748,0.00068829587,0.000013136135,0.0181432,0.0005534834,6.1339307e-7,0.00015011991,4.1890512e-8,0.00017682528,0.00006881044,0.976496,0.003642761],"study_design_scores_gemma":[0.0013593732,0.0003336716,0.002000082,0.027062738,0.00088602677,0.000024586088,0.000027151134,0.000022919618,0.0015463115,0.000022600152,0.96642786,0.00028666205],"about_ca_topic_score_codex":0.00013153134,"about_ca_topic_score_gemma":0.0000013819351,"teacher_disagreement_score":0.121000364,"about_ca_system_score_codex":0.00014934187,"about_ca_system_score_gemma":0.0009148543,"threshold_uncertainty_score":0.99987245},"labels":[],"label_agreement":null},{"id":"W4238840287","doi":"10.21203/rs.3.rs-17454/v1","title":"Activated CAMKKb-AMPK Signaling Promotes Autophagy in a Spheroid Model of Ovarian Tumour Metastasis","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"China Scholarship Council; Ovarian Cancer Canada; Cancer Research Society","keywords":"Autophagy; Spheroid; AMPK; Cell biology; Viability assay; Chemistry; Cancer research; Protein kinase A; Cell; Apoptosis; Biology; Phosphorylation; In vitro; Biochemistry","score_opus":0.13507863882055082,"score_gpt":0.412778643504134,"score_spread":0.2777000046835832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4238840287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906562,0.0020847616,0.000943458,0.0018423648,0.000060864502,0.0028186382,0.00033082606,0.00015319976,0.0011096782],"genre_scores_gemma":[0.99534327,0.00025821378,0.0031210263,0.00008214222,0.00019792661,0.00033443244,0.0003032597,0.00012042574,0.00023930843],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9950005,0.00067818287,0.0007794068,0.00098327,0.0017159206,0.00084270985],"domain_scores_gemma":[0.9973414,0.00029405282,0.00022946513,0.0009241814,0.00068967545,0.00052125164],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.001394069,0.00044779532,0.0012242685,0.0006815618,0.00010427889,0.00006158374,0.00055015646,0.00048269777,0.00064893335],"category_scores_gemma":[0.0008363897,0.0004090443,0.0004242215,0.0008994321,0.0002000561,0.000098413024,0.00076823094,0.0027101366,0.0000397786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028439283,0.0016819718,0.00085685425,0.0077611636,0.0010934781,0.0011870114,0.0039831316,0.0083772475,0.9661679,0.0012340979,0.00042098056,0.0043922113],"study_design_scores_gemma":[0.0033126606,0.00070804096,0.004944727,0.0039021275,0.00017823114,0.000010962006,0.00081339927,0.093372,0.87226343,0.019929336,0.00006878466,0.00049628876],"about_ca_topic_score_codex":0.00083587813,"about_ca_topic_score_gemma":0.000021459608,"teacher_disagreement_score":0.09390448,"about_ca_system_score_codex":0.00037793472,"about_ca_system_score_gemma":0.0026532037,"threshold_uncertainty_score":0.99983615},"labels":[],"label_agreement":null},{"id":"W4242318074","doi":"10.1016/s0076-6879(17)30062-9","title":"Preface","year":2017,"lang":"en","type":"editorial","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Cancer Research; Fondation Bettencourt Schueller; Institut National Du Cancer; Agence Nationale de la Recherche","keywords":"Philosophy","score_opus":0.05407252902339617,"score_gpt":0.48578581467438525,"score_spread":0.4317132856509891,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242318074","genre_codex":"editorial","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007596687,0.011814398,0.019487724,0.0010064091,0.9286398,0.0031038644,0.0002508926,0.00050950854,0.027590714],"genre_scores_gemma":[0.00038339407,0.002660746,0.7552851,0.001623233,0.22573808,0.0010780893,0.00045561235,0.0005119041,0.012263859],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.96860814,0.020682096,0.0030162064,0.0038109717,0.001056598,0.0028259982],"domain_scores_gemma":[0.96645737,0.02522221,0.0018861677,0.0052989414,0.00046358086,0.00067175244],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.019071257,0.0021946644,0.00647583,0.0028777807,0.00036183192,0.00008111399,0.0027674085,0.010570379,0.0016186285],"category_scores_gemma":[0.03488602,0.0021279217,0.0010368488,0.00087498646,0.0023150588,0.00020397022,0.0009135471,0.010332944,0.0002684263],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007607716,0.00385644,0.0019214997,0.001081426,0.001516292,0.010657712,0.0014057704,0.000092093134,0.018844774,0.0031378756,0.7583439,0.1915345],"study_design_scores_gemma":[0.009985787,0.0033446478,0.02314822,0.00093788304,0.0006032749,0.0004794394,0.000101909245,0.000058644266,0.005541236,0.037696745,0.91616637,0.0019358739],"about_ca_topic_score_codex":0.000612562,"about_ca_topic_score_gemma":0.00058750197,"teacher_disagreement_score":0.73579735,"about_ca_system_score_codex":0.0012511505,"about_ca_system_score_gemma":0.0021448075,"threshold_uncertainty_score":0.99929404},"labels":[],"label_agreement":null},{"id":"W4242344611","doi":"10.1158/1538-7445.sabcs18-2619","title":"Abstract 2619: DNA damage agents promote TFEB function and induce pro-survival autophagy signals","year":2019,"lang":"en","type":"article","venue":"Molecular and Cellular Biology / Genetics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"TFEB; Autophagy; DNA damage; Biology; Cancer research; Cell biology; mTORC1; DNA repair; DNA; PI3K/AKT/mTOR pathway; Signal transduction; Biochemistry","score_opus":0.0144512007074159,"score_gpt":0.26271097649675923,"score_spread":0.24825977578934333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242344611","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99076265,0.006135097,0.0010222663,0.00009993888,0.00025557118,0.000656405,0.000013075109,0.000045209174,0.0010097955],"genre_scores_gemma":[0.99829674,0.00024632263,0.00021169941,0.0006438365,0.00008642422,0.000015065768,0.00014241066,0.000036013076,0.00032148923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987493,0.000084702035,0.00024815672,0.00046766427,0.00014118633,0.00030898288],"domain_scores_gemma":[0.9992871,0.000015627615,0.000090862566,0.00035278607,0.000056447756,0.00019715303],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018713989,0.00023967845,0.00032605566,0.00007776447,0.00006990092,0.00002300031,0.00007950327,0.00029497774,0.00024139934],"category_scores_gemma":[0.000012531032,0.00021054487,0.000082640225,0.00008912545,0.00012707943,0.000021146658,0.00007393269,0.00020185769,0.000052868952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012922582,0.00011640482,0.010155259,0.000096010124,0.00020497439,0.00010207464,0.00008586896,0.0000053335825,0.98215955,0.00021340702,0.000013638976,0.006718226],"study_design_scores_gemma":[0.0025989895,0.0011895349,0.13896899,0.000046588753,0.00025217712,0.000027131331,0.000064513464,0.00036427766,0.8506507,0.0026038964,0.002897106,0.00033608777],"about_ca_topic_score_codex":0.0000058329556,"about_ca_topic_score_gemma":4.7202406e-7,"teacher_disagreement_score":0.13150886,"about_ca_system_score_codex":0.000012959157,"about_ca_system_score_gemma":0.000064073916,"threshold_uncertainty_score":0.858577},"labels":[],"label_agreement":null},{"id":"W4245039061","doi":"10.7287/peerj.preprints.556","title":"Systematic review of the statistical scope used in studies based on skeletal muscle autophagy and exercise","year":2014,"lang":"en","type":"preprint","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Scope (computer science); Skeletal muscle; Autophagy; Credibility; Statistical analysis; Bioinformatics; Medicine; Physiology; Computer science; Biology; Statistics; Internal medicine; Mathematics; Biochemistry","score_opus":0.023696054730861213,"score_gpt":0.33435198953030265,"score_spread":0.3106559347994414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4245039061","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.25251782,0.72009045,0.0014548897,0.0026313302,0.00096229994,0.018802349,0.00018914019,0.00018363527,0.0031680516],"genre_scores_gemma":[0.96588033,0.029959472,0.00047555545,0.0028714363,0.000038587972,0.00039120705,0.00002811153,0.000034836845,0.0003204792],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.9979758,0.0003264488,0.00074793777,0.00034343527,0.00044467795,0.00016166693],"domain_scores_gemma":[0.998163,0.0004931506,0.0002736848,0.0008812222,0.00010184769,0.00008712015],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007471497,0.00026967912,0.0017244411,0.000083642015,0.000027028076,0.000008331072,0.0001633081,0.00011908394,0.00018018161],"category_scores_gemma":[0.0007963631,0.0001444654,0.00017930064,0.00009369576,0.0001746083,0.000011874617,0.00016938153,0.00032090233,0.000011854985],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003544778,0.00024419802,0.000083298975,0.99768263,0.00017481676,0.000030429817,0.00010149296,0.000014940521,0.000018952047,0.0006385449,0.00053357054,0.00044167423],"study_design_scores_gemma":[0.0014587225,0.0001769295,0.012977096,0.9792912,0.0015298991,0.0000028160716,0.000069235735,0.0031075913,0.0004488,0.0007093513,0.000014949665,0.0002134006],"about_ca_topic_score_codex":0.000021251533,"about_ca_topic_score_gemma":0.000004337813,"teacher_disagreement_score":0.71336246,"about_ca_system_score_codex":0.00006110074,"about_ca_system_score_gemma":0.0001921312,"threshold_uncertainty_score":0.5891128},"labels":[],"label_agreement":null},{"id":"W4245323140","doi":"10.1002/9781119312994.apr0264","title":"Membrane Dynamics and Regulation of Subcellular Changes during Senescence","year":2017,"lang":"en","type":"other","venue":"Annual Plant Reviews online","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Senescence; Membrane; Autophagy; Proteolysis; Cell biology; Biology; Metabolism; Chemistry; Biochemistry; Enzyme","score_opus":0.018498538675444143,"score_gpt":0.2882283641611042,"score_spread":0.26972982548566005,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4245323140","genre_codex":"review","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06922012,0.8473567,0.00016917419,0.0014669689,0.0010359216,0.0061620483,0.02105722,0.00042179556,0.053110104],"genre_scores_gemma":[0.0029730946,0.45593747,0.0004780863,0.00014293539,0.0008574368,0.000014660579,0.005682184,0.00018839189,0.53372574],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991001,0.00003961801,0.00025683854,0.0002754952,0.00017447406,0.00015346266],"domain_scores_gemma":[0.99876773,0.000013697179,0.00054472307,0.0005392518,0.000036396297,0.00009821173],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013664452,0.00025659954,0.0008848954,0.00013258906,0.000036850597,0.0000059440945,0.000113252194,0.00021299509,0.00024223594],"category_scores_gemma":[0.000042883497,0.00019551457,0.00009268388,0.000044531564,0.00008886713,0.00003208429,0.000039217983,0.00014075034,0.000011227262],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019812123,0.002653844,0.006965432,0.103655025,0.0025027464,0.001913069,0.0009155079,0.0000014706839,0.070664,0.0016540173,0.33022264,0.476871],"study_design_scores_gemma":[0.0010748877,0.000153752,0.005015779,0.012808229,0.0004925288,0.00017179383,0.000020404832,0.00019655081,0.0021250148,0.000008663286,0.97758764,0.00034476226],"about_ca_topic_score_codex":0.000094062874,"about_ca_topic_score_gemma":0.0004177222,"teacher_disagreement_score":0.647365,"about_ca_system_score_codex":0.0000159826,"about_ca_system_score_gemma":0.000037830476,"threshold_uncertainty_score":0.79728526},"labels":[],"label_agreement":null},{"id":"W4246055142","doi":"10.3410/f.736989591.793576935","title":"Faculty Opinions recommendation of Image-Based Morphological Profiling Identifies a Lysosomotropic, Iron-Sequestering Autophagy Inhibitor.","year":2020,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"European commission; Autophagy; Profiling (computer programming); Mode of action; Small molecule; Chemistry; Proteomics; Political science; Computational biology; Library science; Biochemistry; Biology; Computer science; European union; Apoptosis; Business; Gene","score_opus":0.037719717961111995,"score_gpt":0.36169865437179777,"score_spread":0.32397893641068576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4246055142","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000017692057,0.001339159,0.00009413723,0.12875038,0.0008565241,0.0019304,0.8668798,0.000103975704,0.00002791376],"genre_scores_gemma":[0.00008117454,0.00036671202,0.0020632646,0.008643141,0.0006441417,0.00034296527,0.9874694,0.000046935264,0.00034226617],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99447906,0.0005075034,0.002013412,0.0009095697,0.0016524486,0.0004379767],"domain_scores_gemma":[0.992422,0.00014388651,0.0016148337,0.0014758899,0.003847506,0.00049589213],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00078997377,0.0006881559,0.0014782728,0.00036344858,0.00022884157,0.00015089686,0.0011283492,0.00082296476,0.00075134315],"category_scores_gemma":[0.0050925617,0.00044869672,0.001043164,0.0016056785,0.0005587025,0.00033485424,0.00046576947,0.0013883577,0.00011310469],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008520986,0.00064133253,0.000008500645,0.01574309,0.0002004867,0.000009258783,0.00004990093,1.8659918e-7,0.0002097725,0.000072972245,0.9819151,0.0010641492],"study_design_scores_gemma":[0.0016215394,0.00034652883,0.001421722,0.0131967515,0.00046159257,0.00008619779,0.000020906267,0.00003721456,0.0016430226,0.00002511039,0.9807696,0.00036981597],"about_ca_topic_score_codex":0.000021719243,"about_ca_topic_score_gemma":8.1296156e-7,"teacher_disagreement_score":0.12058959,"about_ca_system_score_codex":0.00017194345,"about_ca_system_score_gemma":0.0008914754,"threshold_uncertainty_score":0.99979645},"labels":[],"label_agreement":null},{"id":"W4246191171","doi":"10.1080/15548627.2020.1787721","title":"Beth Levine in memoriam","year":2020,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Queen's University Belfast; Yale University; Queen's University; Ellison Medical Foundation","keywords":"Biology; Gerontology; Medicine","score_opus":0.03549578718835899,"score_gpt":0.2858677339201368,"score_spread":0.2503719467317778,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4246191171","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97749066,0.0021722775,0.00013360192,0.0075694225,0.00040990132,0.00031494675,0.0000064167566,0.00019547401,0.011707274],"genre_scores_gemma":[0.9871321,0.00009398904,0.0003189967,0.010890663,0.0008543072,0.0000142689005,0.00001819804,0.00002316547,0.0006543123],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9991503,0.000025795372,0.00020541198,0.00023339303,0.00017210215,0.00021305046],"domain_scores_gemma":[0.9994999,0.000029108318,0.000034312037,0.00019963656,0.000022639437,0.00021439354],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000067947476,0.00011926686,0.00026806345,0.00005025215,0.000021343014,0.000007811006,0.00008949353,0.00006872137,0.0013351339],"category_scores_gemma":[0.000073215146,0.0001049219,0.00008165712,0.0002652975,0.000033196626,0.000061298175,0.000029744462,0.00017061233,0.00041974167],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007262941,0.004989048,0.12336591,0.0019385705,0.0016308668,0.021908084,0.021583406,0.00028844664,0.25153616,0.043885026,0.20711455,0.314497],"study_design_scores_gemma":[0.013915298,0.0015089986,0.55193526,0.00016418677,0.0001804507,0.00008263291,0.00026916902,0.0041929707,0.13988982,0.002568909,0.28464675,0.0006455554],"about_ca_topic_score_codex":0.000018241917,"about_ca_topic_score_gemma":0.0000018858674,"teacher_disagreement_score":0.42856935,"about_ca_system_score_codex":0.00002911884,"about_ca_system_score_gemma":0.00008930091,"threshold_uncertainty_score":0.99957776},"labels":[],"label_agreement":null},{"id":"W4249208128","doi":"10.3410/f.3087957.3129071","title":"Faculty Opinions recommendation of A yeast MAPK cascade regulates pexophagy but not other autophagy pathways.","year":2010,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Autophagy; MAPK/ERK pathway; Yeast; Cascade; Cell biology; Chemistry; Biology; Signal transduction; Genetics; Apoptosis","score_opus":0.03364788953470324,"score_gpt":0.3477101242599941,"score_spread":0.3140622347252908,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4249208128","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000057600042,0.0020365263,0.000012961104,0.066278525,0.0012179697,0.0020323056,0.9281969,0.000090785594,0.00007639614],"genre_scores_gemma":[0.00007531347,0.0004883375,0.0006130725,0.013888397,0.00082058436,0.00032496892,0.9809634,0.000072459574,0.0027534305],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99417,0.00038835092,0.0020419795,0.00094362465,0.0019132113,0.0005428046],"domain_scores_gemma":[0.99020076,0.00014397805,0.0019442408,0.0024504263,0.0046531046,0.00060746697],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011906866,0.0008124774,0.0016145403,0.0005243892,0.00025460735,0.00010609633,0.0014904425,0.0014779427,0.0025437432],"category_scores_gemma":[0.0038204228,0.0005235172,0.0012421455,0.001643717,0.0006194408,0.00030211103,0.00041223146,0.0018714679,0.00013662654],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000092737646,0.0008537059,6.1068187e-7,0.006747684,0.00040421888,0.0000023174484,0.00014980452,3.894247e-8,0.00036689074,0.00026284167,0.9883379,0.0027812908],"study_design_scores_gemma":[0.0016230647,0.0002598743,0.002011425,0.010485613,0.0005314943,0.00016342333,0.00003051265,0.00001010923,0.010880261,0.000046527108,0.9735139,0.00044380323],"about_ca_topic_score_codex":0.00016051035,"about_ca_topic_score_gemma":0.000008396562,"teacher_disagreement_score":0.052766506,"about_ca_system_score_codex":0.00013689493,"about_ca_system_score_gemma":0.0010688276,"threshold_uncertainty_score":0.9998183},"labels":[],"label_agreement":null},{"id":"W4250484950","doi":"10.1158/1538-7445.am2019-3003","title":"Abstract 3003: Inhibiting the mitochondrial enzyme phosphatidylserine decarboxylase (PISD) reduces stemness and increases differentiation in acute myeloid leukemia (AML)","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research; Brock University; Princess Margaret Cancer Centre","funders":"","keywords":"Myeloid leukemia; Clonogenic assay; Cancer research; Myeloid; Biology; Haematopoiesis; Cell growth; Leukemia; Stem cell; Progenitor cell; Cellular differentiation; Chemistry; Cell biology; Immunology; Cell; Biochemistry","score_opus":0.028784465769420748,"score_gpt":0.3506110704357492,"score_spread":0.32182660466632845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4250484950","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99349874,0.004200812,0.0000029739983,0.0006020573,0.0002174358,0.0010483608,0.000028596562,0.000032842338,0.0003681729],"genre_scores_gemma":[0.9964182,0.0019039172,0.000020366046,0.00014318895,0.00049953815,0.00025694267,0.000040509436,0.000034451,0.0006828886],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99803185,0.00015017172,0.000301174,0.00040188583,0.0006453545,0.0004695766],"domain_scores_gemma":[0.9989122,0.0003296897,0.000082601626,0.00032538784,0.00016932384,0.00018075242],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004784827,0.00017251319,0.00029782765,0.00018505128,0.00015791082,0.0000861874,0.00017609484,0.000106298285,0.000626029],"category_scores_gemma":[0.00011543454,0.000120578305,0.000059141286,0.00041159688,0.00017235297,0.00019739481,0.00011738344,0.00054878637,0.000027274747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003320287,0.00021932293,0.02824855,0.00037130644,0.00025103413,0.00015880517,0.0011207974,0.00004281711,0.9377685,0.00021955973,0.0006325865,0.027646396],"study_design_scores_gemma":[0.004975226,0.00021912681,0.30599442,0.00077407423,0.000054730943,0.000016401025,0.00077464076,0.00032493143,0.68577826,0.00037138103,0.0005049887,0.00021183607],"about_ca_topic_score_codex":0.0020306369,"about_ca_topic_score_gemma":0.00018491886,"teacher_disagreement_score":0.27774587,"about_ca_system_score_codex":0.00035507814,"about_ca_system_score_gemma":0.00058816286,"threshold_uncertainty_score":0.6854578},"labels":[],"label_agreement":null},{"id":"W4252518851","doi":"10.3410/f.1331957.801055","title":"Faculty Opinions recommendation of A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation.","year":2009,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Endoplasmic reticulum; Cell biology; Autophagosome; Autophagy; Chemistry; Computer science; Biology; Biochemistry; Apoptosis","score_opus":0.02528964460627063,"score_gpt":0.35028045039812955,"score_spread":0.3249908057918589,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4252518851","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000012435825,0.0013100962,0.00010397361,0.13930377,0.00053539104,0.0035135108,0.85511196,0.000031386622,0.00007747354],"genre_scores_gemma":[0.00016902624,0.00046512508,0.00074941,0.0060754023,0.00023231955,0.0004493787,0.99101895,0.00002968633,0.000810674],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9953035,0.0002914109,0.0020726796,0.0004987804,0.0014486568,0.00038498678],"domain_scores_gemma":[0.99082947,0.00019584148,0.002369472,0.0017914831,0.0045536924,0.00026002503],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011815061,0.00052045844,0.0012480485,0.0003324147,0.0002502997,0.000050579245,0.0013044146,0.00067285995,0.0002584374],"category_scores_gemma":[0.004439239,0.0002805947,0.0013712171,0.0017477509,0.00039822148,0.00035439327,0.00023419588,0.00077397964,0.000012724061],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007482224,0.0006780869,0.0000030333763,0.010780814,0.00022832719,2.1220013e-7,0.00013579408,1.6734599e-7,0.0000121988105,0.0010680737,0.9854783,0.0015401767],"study_design_scores_gemma":[0.0021694042,0.00037481354,0.0020052614,0.0129176965,0.0005391978,0.00008065326,0.00003499941,0.000045026998,0.0005232587,0.00031796287,0.9807428,0.00024891648],"about_ca_topic_score_codex":0.000015445015,"about_ca_topic_score_gemma":0.000003197456,"teacher_disagreement_score":0.13590702,"about_ca_system_score_codex":0.0001381391,"about_ca_system_score_gemma":0.0008039327,"threshold_uncertainty_score":0.9999646},"labels":[],"label_agreement":null},{"id":"W4253335988","doi":"10.22541/au.161597686.60503163/v1","title":"Human Cardiac Ischemia-Reperfusion Injury: Blunted Stress Response with Age","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; University of Toronto; York University","funders":"","keywords":"Autophagy; Ischemia; Medicine; Cardiology; Internal medicine; Mitochondrion; Dysfunctional family; Cohort; Pathological; Reperfusion injury; Endocrinology; Apoptosis; Anesthesia; Chemistry; Biochemistry","score_opus":0.013463338624886823,"score_gpt":0.3074619662286881,"score_spread":0.2939986276038013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4253335988","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9892196,0.0011437304,0.000048685164,0.00047202484,0.00024783163,0.00073660834,0.000102294325,0.0002857606,0.007743444],"genre_scores_gemma":[0.9802739,0.00018888082,0.00067583297,0.00072515034,0.00034169125,0.00010456674,0.0009872654,0.00008862477,0.016614065],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99780405,0.0002113188,0.00034376053,0.00077091757,0.0005502079,0.00031974594],"domain_scores_gemma":[0.9978012,0.00004889546,0.00014808978,0.00148506,0.0002182035,0.0002985781],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00028984898,0.00044573596,0.0008402694,0.0001537126,0.00011353326,0.00008018645,0.00019852177,0.00047173377,0.0019535385],"category_scores_gemma":[0.000049467315,0.00033328193,0.0003503374,0.00016150091,0.00013276306,0.00004419188,0.00045406987,0.00089006947,0.000024377005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018198775,0.0012186449,0.007582815,0.000980146,0.0024818813,0.0051163873,0.0020578615,0.00003013738,0.9491602,0.0001593418,0.010501339,0.0025124298],"study_design_scores_gemma":[0.0019641912,0.00063133286,0.020342583,0.0020936534,0.000763355,0.000015253356,0.001022279,0.000027857743,0.96924514,0.000052274627,0.003173451,0.00066860934],"about_ca_topic_score_codex":0.00018846172,"about_ca_topic_score_gemma":0.000015603395,"teacher_disagreement_score":0.02008492,"about_ca_system_score_codex":0.00013313236,"about_ca_system_score_gemma":0.00060742366,"threshold_uncertainty_score":0.9999119},"labels":[],"label_agreement":null},{"id":"W4254602120","doi":"10.3410/f.12248956.14691086","title":"Faculty Opinions recommendation of SNARE proteins are required for macroautophagy.","year":2011,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Autophagy; Neuroscience; Chemistry; Biology; Biochemistry","score_opus":0.05548992943284886,"score_gpt":0.3762091606440224,"score_spread":0.3207192312111735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4254602120","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000011490331,0.0025753523,0.000073143674,0.12185621,0.0008416227,0.0048257606,0.86968625,0.00006595593,0.000074575546],"genre_scores_gemma":[0.000012204715,0.00053637003,0.0013691515,0.007311568,0.0005539438,0.0013640907,0.9865905,0.00005809581,0.0022040606],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9950951,0.00031388647,0.0019375548,0.00083537033,0.0013441007,0.00047398702],"domain_scores_gemma":[0.98726004,0.000120436154,0.002461663,0.0020858347,0.007601925,0.0004700883],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010973058,0.0006823489,0.001539975,0.0004061216,0.0002675326,0.00006702374,0.0013236136,0.0010042753,0.0010996923],"category_scores_gemma":[0.0057998816,0.00043768174,0.0012785681,0.0015018159,0.00041411028,0.00029557224,0.00031690052,0.00091807515,0.000052255346],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013011401,0.000991476,0.000005869632,0.020752225,0.0004286329,0.0000010439891,0.000121106445,1.1973174e-8,0.0000053909134,0.00033107772,0.9750026,0.0022304873],"study_design_scores_gemma":[0.0020046216,0.00042299664,0.002146934,0.022412289,0.0006187593,0.00005204363,0.000039168375,0.00000468652,0.00016699817,0.000103048915,0.9716502,0.00037824683],"about_ca_topic_score_codex":0.000036214224,"about_ca_topic_score_gemma":0.0000033559613,"teacher_disagreement_score":0.11690429,"about_ca_system_score_codex":0.00014133414,"about_ca_system_score_gemma":0.000899118,"threshold_uncertainty_score":0.99981344},"labels":[],"label_agreement":null},{"id":"W4256159846","doi":"10.21203/rs.3.rs-17454/v2","title":"Activated CAMKKβ-AMPK Signaling Promotes Autophagy in a Spheroid Model of Ovarian Tumour Metastasis","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"China Scholarship Council; Ovarian Cancer Canada; Cancer Research Society","keywords":"Autophagy; AMPK; Spheroid; Cell biology; Viability assay; Chemistry; Cancer research; Protein kinase A; Cell; Apoptosis; Biology; Kinase; In vitro; Biochemistry","score_opus":0.13507863882055082,"score_gpt":0.412778643504134,"score_spread":0.2777000046835832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4256159846","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99066824,0.0020967927,0.0009577358,0.0017847104,0.000060070448,0.0028291242,0.0003286117,0.00015378228,0.001120923],"genre_scores_gemma":[0.9953199,0.00026491497,0.003142115,0.00008008366,0.00019513215,0.00034301242,0.00029766533,0.00012142743,0.00023573481],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9949889,0.00068022223,0.00078120874,0.000985293,0.0017195878,0.0008447419],"domain_scores_gemma":[0.9973369,0.00029498865,0.00022989027,0.0009255668,0.0006907475,0.0005219023],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0014019166,0.00044834884,0.00122704,0.0006823035,0.000104741346,0.000061651896,0.0005504777,0.00048326,0.0006597859],"category_scores_gemma":[0.00084259536,0.00040938056,0.00042481508,0.00090097525,0.0002010571,0.0000976207,0.0007761623,0.0027182796,0.00003938695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027899793,0.0016689933,0.00083721936,0.00768879,0.001071857,0.0011597049,0.0038715112,0.00801374,0.96700937,0.0013009605,0.00040087028,0.0041869967],"study_design_scores_gemma":[0.0032860856,0.00069042225,0.004641842,0.0038638422,0.00017790528,0.000010743467,0.00080627645,0.0906926,0.8750992,0.020179726,0.00006343335,0.00048791984],"about_ca_topic_score_codex":0.00083084276,"about_ca_topic_score_gemma":0.000021924068,"teacher_disagreement_score":0.091910176,"about_ca_system_score_codex":0.00038233062,"about_ca_system_score_gemma":0.0026839615,"threshold_uncertainty_score":0.9998358},"labels":[],"label_agreement":null},{"id":"W4256182124","doi":"10.21203/rs.3.rs-62994/v2","title":"Inhibition of Ref(2)P, the Drosophila homologue of p62/SQSTM1, increases lifespan and leads to motor function decline","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Drosophila (subgenus); Motor function; Function (biology); Biology; Genetics; Physical medicine and rehabilitation; Medicine; Gene","score_opus":0.06998656023433725,"score_gpt":0.39100906930843243,"score_spread":0.3210225090740952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4256182124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98734295,0.0030258067,0.00012137753,0.006780701,0.00007543918,0.0018009748,0.00040359425,0.00004642099,0.00040273563],"genre_scores_gemma":[0.99665004,0.0013060721,0.0001110379,0.00050529314,0.00060610834,0.00020615336,0.00039379523,0.00004131501,0.00018019867],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9971809,0.00048453608,0.0004832287,0.0004928615,0.0010507496,0.00030774597],"domain_scores_gemma":[0.9975539,0.00045928275,0.00017010699,0.0007495633,0.0007266442,0.0003404913],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011007912,0.00022040922,0.00057814026,0.00036888776,0.00011333247,0.000024291738,0.00019769068,0.0002950581,0.00015558605],"category_scores_gemma":[0.0012372409,0.00015917294,0.00019532845,0.00044590057,0.0004062029,0.00004227402,0.00087705365,0.00094635674,0.000021302825],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.050642714,0.0058732964,0.10724068,0.034551956,0.0025616046,0.0012128089,0.006203445,0.00024469564,0.7118708,0.011011653,0.027802508,0.040783864],"study_design_scores_gemma":[0.0042821895,0.010501409,0.8307659,0.006720255,0.00053185964,0.000046175388,0.0014706437,0.0005052417,0.11081648,0.0299216,0.0038915207,0.0005467007],"about_ca_topic_score_codex":0.000611337,"about_ca_topic_score_gemma":0.000031400443,"teacher_disagreement_score":0.7235252,"about_ca_system_score_codex":0.00008201397,"about_ca_system_score_gemma":0.0004962925,"threshold_uncertainty_score":0.6490884},"labels":[],"label_agreement":null},{"id":"W4280501437","doi":"10.1242/jeb.244145","title":"Activation of p53 in anoxic freshwater crayfish, <i>Faxonius virilis</i>","year":2022,"lang":"en","type":"article","venue":"Journal of Experimental Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Biology; DNA damage; Cell biology; Phosphorylation; Apoptosis; Stress granule; Molecular biology; DNA; Biochemistry; Gene; Messenger RNA; Translation (biology)","score_opus":0.017036486917644367,"score_gpt":0.3090517351970892,"score_spread":0.2920152482794448,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280501437","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967238,0.0018733782,0.00001111864,0.00042240834,0.00025897898,0.00010296771,0.000011510762,0.0000037300956,0.0005921186],"genre_scores_gemma":[0.9980994,0.000036648013,0.0001541148,0.0015195285,0.000104948944,0.000009102202,0.000014180362,0.000008207006,0.000053871536],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991985,0.00009995177,0.0003735043,0.00008440562,0.00012555624,0.00011805926],"domain_scores_gemma":[0.9995494,0.00003122135,0.00023303709,0.000094998264,0.00004073053,0.00005061531],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016171792,0.00007487965,0.00026729438,0.00017320395,0.000031230174,0.0000018194037,0.000091614944,0.00004253706,0.0016293714],"category_scores_gemma":[0.000016308517,0.000058959216,0.00010834577,0.00010855892,0.000060518974,0.00006755932,0.000046052435,0.00018953948,0.0000018549151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013807097,0.0006782236,0.006295641,0.000004406482,0.00006177617,0.00005780446,0.0006259441,0.000009013696,0.9889193,0.00008639347,0.001588206,0.00029255523],"study_design_scores_gemma":[0.0024934649,0.0021977462,0.0022458036,0.00001698146,0.000011858052,0.0001723052,0.001460299,0.00001606708,0.9833822,0.00021049056,0.00773946,0.00005332432],"about_ca_topic_score_codex":0.0000158102,"about_ca_topic_score_gemma":0.0000010660067,"teacher_disagreement_score":0.0061512543,"about_ca_system_score_codex":0.00012288115,"about_ca_system_score_gemma":0.000066516426,"threshold_uncertainty_score":0.99928325},"labels":[],"label_agreement":null},{"id":"W4280520691","doi":"10.1007/s10126-022-10132-0","title":"Regulation of Apoptosis and Autophagy During Anoxia in the Freshwater Crayfish, Faxonius virilis","year":2022,"lang":"en","type":"review","venue":"Marine Biotechnology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Biology; Apoptosis; Cell biology; Hepatopancreas; Crayfish; Drosophila virilis; Programmed cell death; Hypoxia (environmental); Ecology; Biochemistry; Oxygen; Gene","score_opus":0.024220983493334715,"score_gpt":0.2885422488459174,"score_spread":0.26432126535258266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280520691","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0404188,0.9569419,0.0000028881166,0.00063464994,0.0001277557,0.0011158047,0.00004479613,0.00012079946,0.00059259514],"genre_scores_gemma":[0.0041214884,0.99470913,0.0001233638,0.00010648886,0.00006454658,0.00021389012,0.00019742108,0.000042512886,0.000421125],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984209,0.00014495954,0.00056024536,0.00041376322,0.0002004953,0.00025965384],"domain_scores_gemma":[0.9988401,0.00008955033,0.00025891585,0.00076125166,0.000017641505,0.000032528547],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022631424,0.00030091451,0.0011696342,0.0006165805,0.00007162018,0.000008833999,0.00030461725,0.0006156819,0.0010747437],"category_scores_gemma":[0.00007744988,0.00020360138,0.00021610742,0.000587984,0.00021427793,0.000030450872,0.00040272364,0.0006848581,0.0000066844987],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000072520554,0.00019707091,0.00015596517,0.0064350856,0.00024261078,0.00008059546,0.00007299939,2.364433e-7,0.00032890952,0.00082803366,0.00019966718,0.9913863],"study_design_scores_gemma":[0.0006947206,0.00022122168,0.002146096,0.0006055939,0.00047947344,0.000266417,0.0000428429,0.000009060517,0.0021247726,0.00036661027,0.9928432,0.00019996418],"about_ca_topic_score_codex":0.00014937142,"about_ca_topic_score_gemma":0.000050431845,"teacher_disagreement_score":0.99264354,"about_ca_system_score_codex":0.000103781895,"about_ca_system_score_gemma":0.00007896732,"threshold_uncertainty_score":0.9998384},"labels":[],"label_agreement":null},{"id":"W4280559566","doi":"10.1016/j.devcel.2022.04.020","title":"DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism","year":2022,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Institute of General Medical Sciences; Biotechnology and Biological Sciences Research Council; Medical Research Council; Manchester Biomedical Research Centre; National Institutes of Health; Barwon Health Foundation; Innovative Medicines Initiative; European Commission; H2020 Marie Skłodowska-Curie Actions; BHF Centre of Research Excellence, Oxford; Diabetes UK; National Heart and Lung Institute; Wellcome Trust; British Heart Foundation; Cancer Research UK; Breast Cancer Now; European Molecular Biology Organization","keywords":"Mitophagy; Biology; Cell biology; Embryonic stem cell; Apoptosis; Mitochondrial fission; Germline; DNM1L; Embryoid body; Programmed cell death; Induced pluripotent stem cell; Cellular differentiation; Mitochondrion; Genetics; Autophagy","score_opus":0.02148476539956,"score_gpt":0.24074289340722532,"score_spread":0.2192581280076653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280559566","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994449,0.00050772674,0.00016809074,0.0002674071,0.00047558115,0.00066708116,0.000026027672,0.00010538016,0.0033336778],"genre_scores_gemma":[0.99191123,0.00006903708,0.00036831637,0.0011194245,0.00010624435,0.00022399338,0.00008127545,0.000048497895,0.006071981],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982515,0.00006122913,0.00030244715,0.00037171855,0.00063473,0.00037835405],"domain_scores_gemma":[0.9994382,0.00003150821,0.00012061754,0.00028947464,0.000024923493,0.00009524837],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001387598,0.00024334526,0.00024284505,0.00007138007,0.0006783097,0.00003331211,0.0002573871,0.00005022698,0.0025398147],"category_scores_gemma":[0.0000054219586,0.00019001364,0.00013529055,0.0001975186,0.000035257606,0.0001028674,0.00029636722,0.00032668235,0.00011659749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00086085894,0.0018704184,0.005396102,0.00039472975,0.0006421894,0.0009416792,0.0093380315,0.00007095276,0.9749276,0.0026353393,0.0008612153,0.0020608755],"study_design_scores_gemma":[0.0039489893,0.00017949834,0.07248842,0.000032431035,0.00012005309,0.0003102905,0.001532822,0.00021583955,0.91713095,0.0027090646,0.0009469536,0.00038469743],"about_ca_topic_score_codex":0.000010713635,"about_ca_topic_score_gemma":0.000002917615,"teacher_disagreement_score":0.06709232,"about_ca_system_score_codex":0.00040241375,"about_ca_system_score_gemma":0.0001671689,"threshold_uncertainty_score":0.998372},"labels":[],"label_agreement":null},{"id":"W4280561623","doi":"10.1111/are.15896","title":"Autophagy‐related gene regulation in liver and muscle of rainbow trout ( <i>Oncorhynchus mykiss</i> ) upon exposure to chloroquine, deoxynivalenol and nutrient restriction","year":2022,"lang":"en","type":"article","venue":"Aquaculture Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; Mowi (Canada)","funders":"Ontario Veterinary College, University of Guelph; Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Agriculture, Food and Rural Affairs","keywords":"Rainbow trout; Biology; Autophagy; ATG12; ATG5; Internal medicine; Endocrinology; Animal science; Biochemistry; Fishery; Apoptosis; Fish <Actinopterygii>","score_opus":0.027365098458952998,"score_gpt":0.31426870675416174,"score_spread":0.2869036082952087,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280561623","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908433,0.006185156,0.000019986788,0.001139731,0.000036127694,0.0011325895,0.000031363194,0.00003887307,0.0005728841],"genre_scores_gemma":[0.9967943,0.0013843372,0.00019513494,0.00011623343,0.00007641755,0.00013992873,0.000084360065,0.000025119376,0.0011841696],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99768585,0.00034896546,0.00034815443,0.00043867828,0.00081907073,0.00035925637],"domain_scores_gemma":[0.99909157,0.00011726843,0.00007339023,0.00030123084,0.00018531054,0.00023125924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009386345,0.00015282551,0.00029732464,0.00044073063,0.00023945994,0.000019927087,0.00010520961,0.00013547389,0.00021764055],"category_scores_gemma":[0.00012847078,0.00013519368,0.00005520382,0.0011442831,0.000089888796,0.0001064146,0.00016319884,0.00056221796,0.000006084027],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027956273,0.0010291691,0.0073526977,0.0002617078,0.00013132163,0.00039470175,0.011142393,0.0002662428,0.9417673,0.002680992,0.0035097986,0.028668068],"study_design_scores_gemma":[0.007744557,0.0039584856,0.8689301,0.00019195146,0.000069923575,0.00016342221,0.0025235487,0.0015163757,0.10011408,0.0018844631,0.012590667,0.00031240736],"about_ca_topic_score_codex":0.00018952927,"about_ca_topic_score_gemma":0.000016846954,"teacher_disagreement_score":0.8615774,"about_ca_system_score_codex":0.0001896813,"about_ca_system_score_gemma":0.00010920281,"threshold_uncertainty_score":0.55130386},"labels":[],"label_agreement":null},{"id":"W4280617428","doi":"10.1016/j.bbamcr.2022.119284","title":"Autophagy regulates transforming growth factor β signaling and receptor trafficking","year":2022,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cell biology; Autophagy; Signal transduction; Small interfering RNA; Transforming growth factor; Biology; Cell migration; Phosphorylation; Cell; Endosome; Chemistry; Cell culture; Intracellular; Transfection; Biochemistry; Apoptosis","score_opus":0.030187884792890682,"score_gpt":0.3163226968028749,"score_spread":0.2861348120099842,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280617428","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99420446,0.0013259832,0.000060414288,0.0019144026,0.0001252648,0.0010138163,0.00008028133,0.0001663207,0.0011090696],"genre_scores_gemma":[0.99749935,0.0004015451,0.00047963165,0.0005254619,0.00019111,0.0001551399,0.00016006122,0.00013439236,0.000453296],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9956054,0.0006304443,0.00043123288,0.00089784176,0.0014962889,0.0009387759],"domain_scores_gemma":[0.9984068,0.00026242,0.00010978255,0.00056687155,0.00019671698,0.0004573774],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00077333365,0.00038805208,0.00050277467,0.0005057146,0.00076389237,0.00013177113,0.00043378596,0.00014672396,0.00047840638],"category_scores_gemma":[0.000059092985,0.0003791838,0.00031874602,0.00094576704,0.00031774846,0.00014796073,0.00028651042,0.0011967022,0.000026198059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005598197,0.0005385985,0.000004284743,0.00020867882,0.0001813758,0.00017901625,0.001900579,0.000008139511,0.99394953,0.00043809877,0.00031060993,0.0017212776],"study_design_scores_gemma":[0.0016567399,0.0009387563,0.00035515352,0.00007475429,0.000074113035,0.000021831163,0.00065045484,0.00040283168,0.9937292,0.00034251335,0.0013743802,0.00037929983],"about_ca_topic_score_codex":0.00004420018,"about_ca_topic_score_gemma":3.8390846e-7,"teacher_disagreement_score":0.0032949147,"about_ca_system_score_codex":0.00019646897,"about_ca_system_score_gemma":0.00043336232,"threshold_uncertainty_score":0.999866},"labels":[],"label_agreement":null},{"id":"W4281387929","doi":"10.1101/2022.05.18.492560","title":"AI-guided screen identifies probucol-mediated mitophagy enhancement through modulation of lipid droplets","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Toronto Western Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Probucol; Parkin; Mitochondrion; Cell biology; PINK1; Chemistry; Lipid droplet; Biology; Autophagy; Biochemistry; Cholesterol; Parkinson's disease; Apoptosis; Medicine; Internal medicine","score_opus":0.021786196008850813,"score_gpt":0.2734874085743154,"score_spread":0.2517012125654646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281387929","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898604,0.0024418065,0.0021378093,0.0005604573,0.0016467284,0.002484783,0.00042979166,0.00038836405,0.00004985671],"genre_scores_gemma":[0.9943191,0.00086674705,0.0021431122,0.0009759789,0.0007305389,0.0007065926,0.000018268183,0.00017639293,0.00006329461],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9958231,0.00021355395,0.0011607393,0.0011283793,0.0010970143,0.0005772241],"domain_scores_gemma":[0.99626905,0.000071340444,0.00088965835,0.0017537696,0.0007515106,0.00026469378],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005236851,0.00066183944,0.0010915794,0.00035070302,0.00020013512,0.00007923596,0.0005051479,0.00047259088,0.0015820378],"category_scores_gemma":[0.00020529487,0.00070675765,0.0003791685,0.0006865105,0.00018540425,0.00022591162,0.00058030104,0.0008568655,0.00006470291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029212428,0.00088357466,0.0058389567,0.0013621378,0.0009541356,0.0001282674,0.00006794352,0.00017684011,0.9872366,0.00039312363,0.0026630405,0.0000032272658],"study_design_scores_gemma":[0.0023867425,0.0002866131,0.1556019,0.0006722153,0.00043334143,5.1588692e-8,0.000010387068,0.0010611487,0.83245784,0.000021488928,0.0062764017,0.0007918523],"about_ca_topic_score_codex":0.00013303467,"about_ca_topic_score_gemma":0.00000125656,"teacher_disagreement_score":0.15477876,"about_ca_system_score_codex":0.00045827107,"about_ca_system_score_gemma":0.0010917688,"threshold_uncertainty_score":0.99953836},"labels":[],"label_agreement":null},{"id":"W4281691426","doi":"10.1038/s41467-022-30654-4","title":"Macrophages disseminate pathogen associated molecular patterns through the direct extracellular release of the soluble content of their phagolysosomes","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Phagocytosis; Pathogen; Phagosome; Biology; Cell biology; Proinflammatory cytokine; Autophagy; Inflammation; Macrophage; Immune system; Extracellular; Endocytosis; Microbiology; Receptor; Immunology; Biochemistry; Apoptosis","score_opus":0.02434923976383368,"score_gpt":0.2895241615056828,"score_spread":0.2651749217418491,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281691426","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8969994,0.09307037,0.000019323652,0.0071934317,0.00020510625,0.0007002199,0.00060235447,0.000039187587,0.0011705694],"genre_scores_gemma":[0.99577236,0.0015381114,0.000056633293,0.00070390943,0.0000116958,0.0001396667,0.00021925195,0.0000278884,0.0015304968],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983944,0.0005812237,0.00033750813,0.00015279377,0.00036926367,0.00016476792],"domain_scores_gemma":[0.9966307,0.00035713057,0.00035975312,0.002429261,0.000185113,0.000038020757],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003161574,0.00014514719,0.00028991976,0.000033110045,0.00045260816,0.0000073557135,0.0012763678,0.000100340825,0.00012346928],"category_scores_gemma":[0.00017115561,0.00008486206,0.00033346468,0.00039655666,0.00025230367,0.000038504677,0.0005865576,0.00087349844,8.2005414e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018488533,0.0027644106,0.023251494,0.000077771954,0.001454757,0.000027507507,0.0060175895,0.00009244854,0.95248574,0.009500875,0.0024808608,0.0016616633],"study_design_scores_gemma":[0.0030061058,0.00035544814,0.14746335,0.00033663135,0.001255795,0.00004235554,0.0075373524,0.00088131183,0.8098555,0.0016647906,0.027189394,0.00041194822],"about_ca_topic_score_codex":0.0000549859,"about_ca_topic_score_gemma":0.00002021869,"teacher_disagreement_score":0.14263022,"about_ca_system_score_codex":0.0000611014,"about_ca_system_score_gemma":0.000099196746,"threshold_uncertainty_score":0.37949646},"labels":[],"label_agreement":null},{"id":"W4281750502","doi":"10.1113/jp282567","title":"Parkin: a potential target to promote healthy ageing","year":2022,"lang":"en","type":"review","venue":"The Journal of Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre; Christie (Canada); Université du Québec à Montréal","funders":"","keywords":"Parkin; Mitophagy; Ubiquitin ligase; Mitochondrion; Cell biology; Biology; Ubiquitin; Ageing; Autophagy; Neurodegeneration; Transcription factor; Mitochondrial biogenesis; Neuroscience; Genetics; Parkinson's disease; Medicine; Apoptosis; Gene","score_opus":0.04335603705911925,"score_gpt":0.36345668734560443,"score_spread":0.32010065028648516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281750502","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001956605,0.9961018,0.000039912677,0.00043815965,0.00078207173,0.00057100813,0.0000134284355,0.000010968991,0.00008607225],"genre_scores_gemma":[0.000626533,0.99557626,0.00014296718,0.0017062702,0.0017244954,0.000017170034,0.000020745987,0.000047019814,0.00013855007],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99785423,0.00069767464,0.0007231167,0.0001486874,0.0002779902,0.000298285],"domain_scores_gemma":[0.9983883,0.00013235291,0.0008417065,0.0003677217,0.000056685156,0.00021324858],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00070722535,0.00024967556,0.0016998939,0.00018011937,0.000142135,0.0000048059414,0.00043345653,0.00011868325,0.0018199849],"category_scores_gemma":[0.00006215958,0.00013535436,0.0006957861,0.0002350197,0.0000536862,0.000025969362,0.00012710945,0.0010291202,0.00005161334],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017759026,0.00043422583,1.9411469e-7,0.006244892,0.002171411,0.00090080086,0.00046809955,0.000041352792,0.0010875673,0.000036597008,0.0077851824,0.9790538],"study_design_scores_gemma":[0.000422738,0.0018120977,0.000035509544,0.0013459839,0.0014057808,0.0014123633,0.000022712968,0.0000030005144,0.000008819172,0.00046449705,0.99295443,0.000112044414],"about_ca_topic_score_codex":0.000005419788,"about_ca_topic_score_gemma":1.5026161e-7,"teacher_disagreement_score":0.9851693,"about_ca_system_score_codex":0.00012388644,"about_ca_system_score_gemma":0.000689516,"threshold_uncertainty_score":0.99909246},"labels":[],"label_agreement":null},{"id":"W4281890156","doi":"10.1038/s41467-022-30374-9","title":"PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Leibniz-Gemeinschaft; Universität Innsbruck; Universitat de Barcelona; Bundesministerium für Bildung und Forschung; European Commission; Phospholipid Research Center; Freistaat Thüringen; Australian Government; Ministère de l'Économie, de la Science et de l'Innovation - Québec; Friedrich-Schiller-Universität Jena; Carl-Zeiss-Stiftung","keywords":"Unfolded protein response; Endoplasmic reticulum; Cell biology; Autophagy; Programmed cell death; Kinase; Apoptosis; Signal transduction; Chemistry; p38 mitogen-activated protein kinases; Protein kinase A; Biology; Biochemistry","score_opus":0.0599512325595382,"score_gpt":0.34841387833458326,"score_spread":0.28846264577504505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281890156","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7590865,0.15371017,0.00013385531,0.051933557,0.0007238622,0.0016997983,0.00084901636,0.0007101126,0.031153165],"genre_scores_gemma":[0.9857768,0.0014695977,0.0014395074,0.009228984,0.00011243188,0.00020448765,0.0006001236,0.00004304786,0.0011250661],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99866813,0.00019548477,0.00022557285,0.00024944454,0.0004223332,0.00023901326],"domain_scores_gemma":[0.9969961,0.00025134915,0.00013593244,0.002330259,0.00013749264,0.00014885177],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018889965,0.00017644335,0.00025764914,0.00015149495,0.00083400746,0.0000291343,0.0010047192,0.00016437491,0.0030802272],"category_scores_gemma":[0.000071278744,0.00017269791,0.00017553702,0.00045822468,0.00011548154,0.00008301552,0.00046784143,0.0016819115,0.000032681924],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023604669,0.015324479,0.10625047,0.00048418305,0.00520601,0.00040937916,0.023238532,0.0004975829,0.27292064,0.046420164,0.4767996,0.050088484],"study_design_scores_gemma":[0.005589235,0.00054760126,0.05848665,0.00030147203,0.00080776226,0.00014797672,0.003943527,0.0022999092,0.11416714,0.0017874563,0.8110429,0.00087838725],"about_ca_topic_score_codex":0.000022945516,"about_ca_topic_score_gemma":0.00001808462,"teacher_disagreement_score":0.33424327,"about_ca_system_score_codex":0.00011529486,"about_ca_system_score_gemma":0.0001701556,"threshold_uncertainty_score":0.9978311},"labels":[],"label_agreement":null},{"id":"W4281978861","doi":"10.21203/rs.3.rs-1648303/v1","title":"STIM1-mediated SOCE Promotes Autophagy through AKT/mTOR Pathway in Hippocampal Neurons after  Ischemic Stroke","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Autophagy; Hippocampal formation; PI3K/AKT/mTOR pathway; Protein kinase B; Neuroscience; Stroke (engine); Chemistry; Cell biology; Signal transduction; Biology; Apoptosis; Engineering; Biochemistry","score_opus":0.05175778626991612,"score_gpt":0.3820146032721585,"score_spread":0.3302568170022424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281978861","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9792558,0.009120936,0.000018234134,0.00144059,0.0004178657,0.003392872,0.0015211938,0.00029208892,0.004540444],"genre_scores_gemma":[0.9880624,0.00085424044,0.00024172831,0.00040960076,0.00061850523,0.002971314,0.0014887468,0.0001927995,0.005160654],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9928703,0.0010099703,0.0007277992,0.0014346255,0.0024566387,0.0015006765],"domain_scores_gemma":[0.99663484,0.0006515291,0.00016053727,0.0016480045,0.00038664328,0.00051844446],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0012654664,0.00061690446,0.00095673464,0.0006809666,0.00023473523,0.000115764546,0.00075415894,0.0006236753,0.010085016],"category_scores_gemma":[0.00090151007,0.0005825842,0.00046855744,0.0007214744,0.00038067467,0.00015405723,0.0018057172,0.005670542,0.00034299318],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.043180596,0.038654562,0.26788887,0.053121287,0.0062945704,0.112811886,0.06620977,0.0010150421,0.21809049,0.0017904856,0.12506753,0.065874904],"study_design_scores_gemma":[0.021906916,0.009260894,0.47624907,0.009149146,0.00044294345,0.00025792228,0.0075666606,0.0060391305,0.15773745,0.011746476,0.2944795,0.0051639024],"about_ca_topic_score_codex":0.0003377009,"about_ca_topic_score_gemma":0.000026502754,"teacher_disagreement_score":0.2083602,"about_ca_system_score_codex":0.000831634,"about_ca_system_score_gemma":0.0029052917,"threshold_uncertainty_score":0.9996626},"labels":[],"label_agreement":null},{"id":"W4282596597","doi":"10.1016/j.ctarc.2022.100592","title":"Interaction between tumor microenvironment, autophagy, and epithelial-mesenchymal transition in tumor progression","year":2022,"lang":"en","type":"review","venue":"Cancer Treatment and Research Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Autophagy; Tumor microenvironment; Metastasis; Cancer research; Carcinogenesis; Epithelial–mesenchymal transition; Tumor progression; Biology; Mechanism (biology); Tumor cells; Apoptosis; Cancer","score_opus":0.19836602034884418,"score_gpt":0.4991227410702917,"score_spread":0.30075672072144755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282596597","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0104238,0.985944,9.503446e-7,0.0007462212,0.000036490317,0.0022027483,0.00030941528,0.000028799614,0.000307593],"genre_scores_gemma":[0.0066951937,0.9881922,0.000106593216,0.000028481349,0.00010753443,0.0035862976,0.0009415949,0.000043950706,0.0002981599],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99778384,0.00083145796,0.0004016969,0.00040880786,0.00025959185,0.00031462588],"domain_scores_gemma":[0.9983067,0.00048060072,0.00013410243,0.0008584898,0.000026608746,0.0001934876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004028672,0.0002760659,0.00080241094,0.0004534864,0.0005329714,0.00004590249,0.00022815843,0.00008877725,0.00031266132],"category_scores_gemma":[0.000019374493,0.00020577172,0.00015974515,0.000360698,0.00040680775,0.00009871389,0.00023861417,0.00077780837,0.000010253883],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060654744,0.00057847355,0.00029465786,0.001496147,0.00027870387,0.0000446236,0.000627605,1.4217997e-7,0.000022720697,0.000030650554,0.000050192237,0.99651545],"study_design_scores_gemma":[0.0012227009,0.0005656658,0.0012130137,0.004813724,0.00060733984,0.00005875841,0.00028857368,0.000029618323,0.000045679055,0.00006164661,0.9909237,0.00016959423],"about_ca_topic_score_codex":0.00031820193,"about_ca_topic_score_gemma":0.00004418864,"teacher_disagreement_score":0.9963458,"about_ca_system_score_codex":0.001060696,"about_ca_system_score_gemma":0.0004601203,"threshold_uncertainty_score":0.8391127},"labels":[],"label_agreement":null},{"id":"W4282832485","doi":"10.1007/s12640-022-00475-w","title":"The Role of PTEN-L in Modulating PINK1-Parkin-Mediated Mitophagy","year":2022,"lang":"en","type":"review","venue":"Neurotoxicity Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Montreal Neurological Institute and Hospital; McGill University","funders":"","keywords":"PINK1; Mitophagy; Parkin; Mitochondrion; Cell biology; Biology; Autophagy; PTEN; Genetics; Parkinson's disease; Signal transduction; PI3K/AKT/mTOR pathway; Medicine; Internal medicine; Apoptosis","score_opus":0.17903098746544543,"score_gpt":0.4663283644636798,"score_spread":0.2872973769982344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282832485","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00501135,0.98676485,3.5380796e-7,0.000052928393,0.00012105625,0.003710279,0.00005355285,0.000043486045,0.004242126],"genre_scores_gemma":[0.005319723,0.99246156,0.000007623663,0.00005039474,0.00022546925,0.0012674193,0.000083962695,0.00010546506,0.0004783653],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9937668,0.0020375524,0.0009673262,0.00062585005,0.0017562273,0.00084622955],"domain_scores_gemma":[0.9945515,0.0036563277,0.0002745096,0.001146238,0.00014102636,0.00023043313],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0023010024,0.0003466557,0.0014614809,0.00064039096,0.00037333253,0.00004034098,0.0008507928,0.00026721237,0.0006277135],"category_scores_gemma":[0.0018540621,0.00024158585,0.0005194627,0.0019832416,0.0003479799,0.00004491616,0.0005176972,0.003016123,0.00007423741],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016657558,0.00041981906,0.00015034316,0.004133782,0.00015716568,0.00030922747,0.00009036938,0.0000014856984,0.0003561943,0.00019411973,0.0001739504,0.99384695],"study_design_scores_gemma":[0.00054893637,0.00033483873,0.00020542413,0.001958273,0.000065468565,0.00004292138,0.00007576385,0.00026030323,0.00029191055,0.00047368734,0.9955774,0.00016510667],"about_ca_topic_score_codex":0.00012259615,"about_ca_topic_score_gemma":0.000009702077,"teacher_disagreement_score":0.9954034,"about_ca_system_score_codex":0.00025380016,"about_ca_system_score_gemma":0.001109295,"threshold_uncertainty_score":0.99928397},"labels":[],"label_agreement":null},{"id":"W4282928367","doi":"10.1186/s13395-022-00296-7","title":"The influence of age, sex, and exercise on autophagy, mitophagy, and lysosome biogenesis in skeletal muscle","year":2022,"lang":"en","type":"article","venue":"Skeletal Muscle","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"TFEB; Mitophagy; Autophagy; Lysosome; Sarcopenia; Skeletal muscle; Biology; Mitochondrion; Mitochondrial biogenesis; Endocrinology; Cell biology; Internal medicine; Biogenesis; Physiology; Medicine; Biochemistry; Gene; Enzyme; Apoptosis","score_opus":0.009068099864217994,"score_gpt":0.2531385690741326,"score_spread":0.24407046920991463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282928367","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993053,0.005533248,7.150603e-7,0.00031449893,0.000105560575,0.0005223226,0.00005009273,0.000046318415,0.00037424135],"genre_scores_gemma":[0.997764,0.0010842545,0.000040647887,0.00037702682,0.000055302273,0.0001236654,0.000015484464,0.00003438287,0.00050526194],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99836165,0.00011255824,0.00036017864,0.00040527762,0.00040636247,0.00035399734],"domain_scores_gemma":[0.99907154,0.00017749856,0.0001133968,0.00044240974,0.000030496429,0.00016463497],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033462507,0.00022315324,0.0003789893,0.0001767943,0.00030490808,0.000023948334,0.00017893309,0.000067960595,0.000089628054],"category_scores_gemma":[0.000050182633,0.00017870088,0.000114671595,0.00039710107,0.00035780173,0.000092982584,0.00021066776,0.00026326202,0.000006579142],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006384438,0.002467147,0.022046672,0.00063976186,0.00033004527,0.0016095669,0.0038000755,0.00056545966,0.2019568,0.0034370394,0.00058698776,0.761922],"study_design_scores_gemma":[0.0021705907,0.00070690096,0.981599,0.00008356428,0.00006216006,0.000026354986,0.00053959375,0.00013312443,0.0047043175,0.0010451564,0.008697894,0.00023139303],"about_ca_topic_score_codex":0.00017650379,"about_ca_topic_score_gemma":0.000015356532,"teacher_disagreement_score":0.9595523,"about_ca_system_score_codex":0.00005197248,"about_ca_system_score_gemma":0.00007404723,"threshold_uncertainty_score":0.7287211},"labels":[],"label_agreement":null},{"id":"W4282944143","doi":"10.1158/1538-7445.am2022-1296","title":"Abstract 1296: MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec","funders":"","keywords":"Chemoimmunotherapy; Cancer research; Medicine; MEK inhibitor; Cancer; Internal medicine; Oncology; Biology; Immunotherapy; Kinase; Cell biology; MAPK/ERK pathway","score_opus":0.06099132534059765,"score_gpt":0.4121338627770085,"score_spread":0.35114253743641083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282944143","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9667581,0.027239602,0.0000021221022,0.002883511,0.00020408587,0.0006414437,0.00017113252,0.000043563847,0.0020564555],"genre_scores_gemma":[0.9848505,0.006186616,0.000015284071,0.0010968787,0.00019050205,0.0012591848,0.000049995262,0.00005799141,0.0062930505],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99741024,0.00016176912,0.00030274317,0.0004588156,0.0010574968,0.0006089371],"domain_scores_gemma":[0.9991286,0.00012232222,0.00007381832,0.00040819595,0.00012604735,0.00014104496],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000928718,0.00016115865,0.00029259457,0.00029266978,0.00032881775,0.000035679423,0.0001971794,0.000078906356,0.008644892],"category_scores_gemma":[0.000021298018,0.0001625391,0.000082684186,0.00088271813,0.00013817832,0.00013273569,0.0000880014,0.001142631,0.000022064356],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015962292,0.00040010008,0.0017043051,0.00017217788,0.0000802243,0.00015832704,0.0015430234,0.00010173064,0.9389789,0.000077215765,0.04799696,0.007190801],"study_design_scores_gemma":[0.005272775,0.00019736217,0.029402709,0.0004938704,0.0000148254,0.000003449553,0.0012622954,0.000029308632,0.81805784,0.00078754977,0.14413354,0.0003445093],"about_ca_topic_score_codex":0.0029523768,"about_ca_topic_score_gemma":0.00028967016,"teacher_disagreement_score":0.1209211,"about_ca_system_score_codex":0.0015720975,"about_ca_system_score_gemma":0.0007889077,"threshold_uncertainty_score":0.99226135},"labels":[],"label_agreement":null},{"id":"W4282972651","doi":"10.1016/j.cellin.2022.100045","title":"Phosphorylated STYK1 restrains the inhibitory role of EGFR in autophagy initiation and EGFR-TKIs sensitivity","year":2022,"lang":"en","type":"article","venue":"Cell Insight","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Hubei University; Wuhan University; Wuhan Science and Technology Project; National Natural Science Foundation of China; Renmin Hospital of Wuhan University; Hubei University of Technology","keywords":"Autophagy; Phosphorylation; Epidermal growth factor receptor; Cancer research; EGFR inhibitors; Cell biology; Carcinogenesis; Chemistry; Biology; Receptor; Biochemistry; Apoptosis","score_opus":0.007441999800784887,"score_gpt":0.2200768584891201,"score_spread":0.2126348586883352,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282972651","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9864606,0.004560768,0.00000321162,0.00023228327,0.000110023546,0.00031708498,0.000020385947,0.000032786502,0.008262845],"genre_scores_gemma":[0.99862397,0.00019799253,0.00001534184,0.000706404,0.000062832594,0.000026219423,0.00004110347,0.000018954172,0.0003072019],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895257,0.00021540442,0.00023584049,0.00020023448,0.00023903493,0.00015692116],"domain_scores_gemma":[0.9994143,0.00012275399,0.000106840984,0.00025089507,0.00004017151,0.00006503839],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002972694,0.00011608209,0.00020881151,0.00010578298,0.00012860389,0.0000072699363,0.000051648596,0.000059744456,0.00022304464],"category_scores_gemma":[0.000024968738,0.00009530858,0.00005534678,0.00027564983,0.00011018751,0.00006463136,0.000073919575,0.00031043857,0.000005255952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010830134,0.0015235045,0.012207997,0.00015810493,0.00012469814,0.000977987,0.027826697,0.0003740703,0.93985736,0.0017120682,0.0010583294,0.013096192],"study_design_scores_gemma":[0.0036565033,0.0004881215,0.2993328,0.000055906286,0.00010165064,0.00006629666,0.002981011,0.003311685,0.66324574,0.0012495874,0.025260895,0.00024983037],"about_ca_topic_score_codex":0.00012494675,"about_ca_topic_score_gemma":0.000020038806,"teacher_disagreement_score":0.28712478,"about_ca_system_score_codex":0.00009197351,"about_ca_system_score_gemma":0.0001488034,"threshold_uncertainty_score":0.3886571},"labels":[],"label_agreement":null},{"id":"W4283389428","doi":"10.1016/j.molcel.2022.06.004","title":"Mitochondrial protein import stress regulates the LC3 lipidation step of mitophagy through NLRX1 and RRBP1","year":2022,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; York University; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Biology; Cell biology; Mitochondrion; Lipid-anchored protein; Endoplasmic reticulum; Autophagy; Biochemistry; Apoptosis","score_opus":0.0057665647058536005,"score_gpt":0.22810780098432537,"score_spread":0.22234123627847177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283389428","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99175775,0.0046165283,0.00048414205,0.0005701118,0.0001905543,0.0008897853,0.000019138013,0.000025428513,0.0014465791],"genre_scores_gemma":[0.9975336,0.000035913425,0.00055965834,0.00048091175,0.00009525034,0.000124524,0.000064215405,0.000026189977,0.0010797192],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99897707,0.00010865307,0.00022873492,0.00022657064,0.0003076595,0.00015128766],"domain_scores_gemma":[0.9993785,0.000018982606,0.00012212586,0.00039903654,0.00003938354,0.000041954692],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008629834,0.00012326268,0.00018996448,0.00004139626,0.00012484053,0.000012017733,0.000119418626,0.000046824676,0.00021600649],"category_scores_gemma":[0.00001292047,0.00009513076,0.00009713145,0.00016694491,0.00008843806,0.00003540693,0.000097740616,0.00015838488,0.0000027854437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054512627,0.00040777228,0.0011616868,0.00017639642,0.0001555343,0.00013253653,0.0005664244,0.000077415665,0.99261856,0.0012736663,0.0011615681,0.0017233068],"study_design_scores_gemma":[0.0021475796,0.00035389827,0.0016988077,0.000035832418,0.0001221826,0.000010719293,0.0003687795,0.00024834368,0.9811772,0.0012830762,0.012440865,0.000112710346],"about_ca_topic_score_codex":0.00007025907,"about_ca_topic_score_gemma":0.0000016894572,"teacher_disagreement_score":0.01144136,"about_ca_system_score_codex":0.000025424168,"about_ca_system_score_gemma":0.00008106413,"threshold_uncertainty_score":0.38793197},"labels":[],"label_agreement":null},{"id":"W4283522616","doi":"10.1016/j.jbc.2022.102187","title":"Inhibition of lipid kinase PIKfyve reveals a role for phosphatase Inpp4b in the regulation of PI(3)P-mediated lysosome dynamics through VPS34 activity","year":2022,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network; Toronto Metropolitan University; Université de Montréal; Montreal Clinical Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto; Canada Research Chairs; Temerty Faculty of Medicine, University of Toronto; Human Frontier Science Program; Canadian Institutes of Health Research; Ryerson University; Cancer Research Society; Canada Foundation for Innovation","keywords":"Lysosome; Endocytic cycle; Cell biology; Phosphatase; Autophagy; Autophagosome; Biology; Phosphatidylinositol; Kinase; Phosphorylation; Biochemistry; Endocytosis; Cell; Enzyme","score_opus":0.02153835043171978,"score_gpt":0.28164666498804974,"score_spread":0.26010831455633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283522616","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980163,0.0006607831,0.000101434474,0.0005281525,0.000035000183,0.00022084563,0.00026587493,0.0000049242935,0.00016667388],"genre_scores_gemma":[0.99908566,0.0001512131,0.00014991908,0.00022779385,0.0001379778,0.000020858051,0.00020490654,0.0000060703833,0.000015620417],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988889,0.00009616565,0.00050688756,0.00011459207,0.00026699773,0.00012642282],"domain_scores_gemma":[0.9986916,0.0002758616,0.00070715183,0.00015797747,0.00011970342,0.00004771451],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062335253,0.000102305086,0.00037504986,0.000029006158,0.00004467426,0.0000031034695,0.000121959325,0.00011245391,0.00017755199],"category_scores_gemma":[0.0003525625,0.00006531707,0.00020602679,0.0002216165,0.00009833117,0.0000622776,0.000037661375,0.000304132,1.8979931e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035254976,0.0012408324,0.0035758682,0.00015343654,0.00006270793,0.000030978023,0.00022890365,0.00005753555,0.9896809,0.0000944442,0.0002277307,0.0011211793],"study_design_scores_gemma":[0.0040366123,0.0014536822,0.044065893,0.00014221821,0.00009184036,0.00012242021,0.0010880391,0.0006391921,0.9412133,0.0066230563,0.00040384693,0.00011988146],"about_ca_topic_score_codex":0.000005206385,"about_ca_topic_score_gemma":2.4537698e-7,"teacher_disagreement_score":0.048467565,"about_ca_system_score_codex":0.00012311306,"about_ca_system_score_gemma":0.0000870741,"threshold_uncertainty_score":0.26635528},"labels":[],"label_agreement":null},{"id":"W4283590652","doi":"10.1186/s12985-022-01840-z","title":"MHBSt167 induced autophagy promote cell proliferation and EMT by activating the immune response in L02 cells","year":2022,"lang":"en","type":"article","venue":"Virology Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Infection and Immunity; National Science and Technology Major Project; Hubei University; Hubei University of Medicine; Natural Science Foundation of Hubei Province","keywords":"Autophagy; Biology; Cell cycle; Immune system; Cell growth; Carcinogenesis; Cell; Flow cytometry; Transfection; Cancer research; Cell biology; Cell culture; Molecular biology; Apoptosis; Immunology; Cancer","score_opus":0.00971697831407557,"score_gpt":0.2572724899178902,"score_spread":0.24755551160381464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283590652","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934641,0.0018225011,0.00004046586,0.003995664,0.00019678126,0.00035909208,0.000004902096,0.000018269653,0.00009822338],"genre_scores_gemma":[0.99769586,0.00008356135,0.00006173487,0.0015476912,0.00010796071,0.00003310329,0.0000048202564,0.000020774143,0.00044446968],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982248,0.0007762636,0.0003375045,0.00017729528,0.00021854833,0.00026558145],"domain_scores_gemma":[0.9993531,0.00014653202,0.00020785842,0.00017564443,0.00002732771,0.000089539375],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013734906,0.0001273774,0.00021675715,0.00014973254,0.00050536764,0.000026870168,0.00012488368,0.00008422971,0.00039482777],"category_scores_gemma":[0.00006379614,0.00009325258,0.00005466859,0.00017625764,0.000059578393,0.000086716725,0.00007623732,0.0010855651,0.000005271653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004086866,0.00025452554,0.0007515112,0.0000066514735,0.00003987816,0.00021683119,0.0023436495,0.000037165504,0.9886964,0.000009641074,0.00031566486,0.0032411963],"study_design_scores_gemma":[0.008391793,0.0041665942,0.16149251,0.000025081054,0.00007514959,0.0021986552,0.0013600937,0.0023370672,0.8134936,0.00079187023,0.0054177134,0.00024984556],"about_ca_topic_score_codex":0.000008283941,"about_ca_topic_score_gemma":4.60462e-7,"teacher_disagreement_score":0.1752028,"about_ca_system_score_codex":0.000094139534,"about_ca_system_score_gemma":0.00019882814,"threshold_uncertainty_score":0.47163004},"labels":[],"label_agreement":null},{"id":"W4283775096","doi":"10.3390/cells11132097","title":"Hallmarks and Molecular Tools for the Study of Mitophagy in Parkinson’s Disease","year":2022,"lang":"en","type":"review","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Parkin; PINK1; Mitochondrion; Autophagy; Dopaminergic; Neuroscience; Biology; Substantia nigra; Parkinson's disease; Cell biology; Dopamine; Disease; Medicine; Genetics; Pathology","score_opus":0.057675020197021726,"score_gpt":0.3456133480811287,"score_spread":0.287938327884107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283775096","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0031062101,0.992139,0.000008803271,0.00002123054,0.00017074337,0.004349803,0.000079950034,0.000009653764,0.00011460337],"genre_scores_gemma":[0.003169012,0.99502903,0.000013865962,0.000149468,0.000072485025,0.0012179611,0.00006366159,0.000046842524,0.00023765095],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99874496,0.00014599627,0.0004024753,0.00032354903,0.00021254654,0.00017049353],"domain_scores_gemma":[0.9984849,0.00066462014,0.00017104024,0.0005479905,0.000016359187,0.00011508123],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022790744,0.00023435464,0.00097438204,0.00009880698,0.000046960413,0.000016513537,0.00019393522,0.000068644455,0.00024681914],"category_scores_gemma":[0.000068643334,0.0001525756,0.0003128275,0.00015714773,0.000043100237,0.00002347458,0.0000839348,0.00021707911,0.0000022315976],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015558364,0.0009568263,0.0000330761,0.009277016,0.00046102313,0.00035368084,0.00020308493,0.0000022045106,0.0000041326334,0.000031768257,0.00045739746,0.9880642],"study_design_scores_gemma":[0.0012076385,0.00027115122,0.00022520928,0.00093705393,0.0016836084,0.0000031191246,0.00019378352,0.000010125138,0.000011254947,0.000038190563,0.99528486,0.00013401604],"about_ca_topic_score_codex":0.000013372966,"about_ca_topic_score_gemma":0.0000017584001,"teacher_disagreement_score":0.99482745,"about_ca_system_score_codex":0.000046326855,"about_ca_system_score_gemma":0.00022402407,"threshold_uncertainty_score":0.6221852},"labels":[],"label_agreement":null},{"id":"W4283782070","doi":"10.1038/s41467-022-31465-3","title":"Endosomal LC3C-pathway selectively targets plasma membrane cargo for autophagic degradation","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital; McGill University; Lunenfeld-Tanenbaum Research Institute; McGill University Health Centre","funders":"Government of Canada; Genentech; Government of Ontario; Canadian Institutes of Health Research; Ontario Genomics; Genome Canada; Deutsches Krebsforschungszentrum; McGill University; U.S. Department of Defense","keywords":"Endocytic cycle; Endosome; Cell biology; Autophagy; ATG8; Retromer; Biology; Signal transducing adaptor protein; Transmembrane protein; Transport protein; Endocytosis; Signal transduction; Receptor; Biochemistry; Intracellular","score_opus":0.02168212314294846,"score_gpt":0.30548256267391216,"score_spread":0.2838004395309637,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283782070","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8682032,0.06332882,0.0011863506,0.031146199,0.0015648709,0.0065913326,0.0019356275,0.0012283837,0.024815198],"genre_scores_gemma":[0.98657376,0.00021870596,0.007053998,0.0016279273,0.00009872241,0.0010000286,0.0016051927,0.00004113917,0.00178052],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988014,0.00016946603,0.00024182543,0.0002524455,0.00029277487,0.00024208748],"domain_scores_gemma":[0.99800646,0.0003456725,0.00012918314,0.0012054925,0.00020265451,0.00011054739],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022979344,0.00016161811,0.00023632968,0.00015881933,0.0009694068,0.000017370829,0.0006240784,0.00015154529,0.00021798883],"category_scores_gemma":[0.00016215944,0.00016300197,0.00017638359,0.00043053634,0.00007460308,0.00009632415,0.00020644489,0.0010184934,0.000012731333],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032616768,0.008768628,0.011389356,0.000347766,0.0027892808,0.000082319995,0.0059073702,0.00055094075,0.33367017,0.5336166,0.05260139,0.047014475],"study_design_scores_gemma":[0.006368552,0.00065490557,0.024544682,0.000030410198,0.0003655711,0.00019129754,0.00055238226,0.013491881,0.094521284,0.0023287507,0.8564588,0.0004914822],"about_ca_topic_score_codex":0.000013548465,"about_ca_topic_score_gemma":0.00003593832,"teacher_disagreement_score":0.8038574,"about_ca_system_score_codex":0.00021763369,"about_ca_system_score_gemma":0.0003560565,"threshold_uncertainty_score":0.74559915},"labels":[],"label_agreement":null},{"id":"W4283802772","doi":"10.3389/fcell.2022.916347","title":"Editorial: Autophagy-Mediated Cell Survival and Death in Disease Progression and Treatment","year":2022,"lang":"en","type":"editorial","venue":"Frontiers in Cell and Developmental Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"Nebraska Center for the Prevention of Obesity Diseases, College of Education and Human Sciences, University of Nebraska–Lincoln; National Institutes of Health; National Natural Science Foundation of China","keywords":"Autophagy; Programmed cell death; Disease; Cell survival; Cell; Medicine; Biology; Cancer research; Apoptosis; Internal medicine; Genetics","score_opus":0.007885805551967303,"score_gpt":0.2614567963845595,"score_spread":0.25357099083259216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283802772","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.20987563,0.022389306,0.0000035815253,0.000035319354,0.7659338,0.00081791857,0.00034138764,0.000042228512,0.00056081073],"genre_scores_gemma":[0.052645322,0.0789959,0.0031798722,0.00013908595,0.85004133,0.00087551225,0.011396965,0.00016515834,0.0025608428],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99788004,0.00017722954,0.00042297013,0.0008115044,0.0002763307,0.00043193885],"domain_scores_gemma":[0.99910176,0.00024584032,0.00013111824,0.00014307977,0.000026307338,0.0003518743],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024401002,0.00046136035,0.000824481,0.0003388806,0.000115966875,0.000022362976,0.000089731555,0.00063771853,0.000068068046],"category_scores_gemma":[0.00007383924,0.00037758242,0.000050757677,0.00014243006,0.00016704341,0.00004893255,0.0001923569,0.00051492656,0.0000025634758],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033738487,0.0008103256,0.21105884,0.000319335,0.000107853615,0.00044463458,0.00074561004,1.7508941e-7,0.00031377547,0.0000037252566,0.77518743,0.0076344134],"study_design_scores_gemma":[0.00901093,0.0008070455,0.017488094,0.00010126717,0.00009322184,0.0000028859554,0.00040200795,0.000022664513,0.00024118369,0.00022692107,0.97114867,0.00045508647],"about_ca_topic_score_codex":0.000096417934,"about_ca_topic_score_gemma":0.0000148788395,"teacher_disagreement_score":0.19596124,"about_ca_system_score_codex":0.0004426011,"about_ca_system_score_gemma":0.0007935846,"threshold_uncertainty_score":0.9998676},"labels":[],"label_agreement":null},{"id":"W4285038131","doi":"10.4161/auto.8.4.19496","title":"Guidelines for the use and interpretation of assays for monitoring autophagy.","year":2012,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique; Montreal Neurological Institute and Hospital","funders":"","keywords":"Autophagy; Interpretation (philosophy); Computational biology; Biochemical engineering; Computer science; Intensive care medicine; Medicine; Biology; Engineering; Biochemistry; Programming language","score_opus":0.08104910026300002,"score_gpt":0.33470993626872136,"score_spread":0.2536608360057213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285038131","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.24733198,0.013171388,0.72661376,0.009108296,0.00061941583,0.0022875515,0.00020033594,0.00012116207,0.00054614374],"genre_scores_gemma":[0.90033656,0.0014792527,0.09503995,0.00013887328,0.00011986849,0.00036516992,0.00024965793,0.000042936455,0.002227744],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983269,0.00051273726,0.00046470008,0.00030850098,0.00019743123,0.00018973088],"domain_scores_gemma":[0.9918684,0.0030036746,0.00041559534,0.0010063625,0.0036033643,0.000102640304],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002780316,0.00019284287,0.00032249387,0.0000822789,0.00016809502,0.00010227363,0.00029775998,0.00017344998,0.000014995883],"category_scores_gemma":[0.0037503256,0.000151493,0.00022674837,0.00007820417,0.00013246619,0.000108943,0.0002589593,0.00019054377,9.912143e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00088525616,0.0014690557,0.017880367,0.0035377324,0.0018272495,0.0000019349225,0.028160572,0.00036237674,0.03039715,0.05717671,0.006075093,0.8522265],"study_design_scores_gemma":[0.004526075,0.0000050825806,0.05681466,0.009294169,0.0016645086,0.000018282733,0.000536954,0.37226835,0.5059019,0.009138081,0.03907176,0.00076017546],"about_ca_topic_score_codex":0.000177832,"about_ca_topic_score_gemma":0.000026419028,"teacher_disagreement_score":0.85146636,"about_ca_system_score_codex":0.00004210499,"about_ca_system_score_gemma":0.0001460633,"threshold_uncertainty_score":0.61777055},"labels":[],"label_agreement":null},{"id":"W4285269469","doi":"10.1007/978-1-0716-2409-8_7","title":"Monitoring Autophagy in Neural Stem and Progenitor Cells","year":2022,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Neural stem cell; Cell biology; Biology; Neurogenesis; Progenitor cell; Stem cell; Programmed cell death; Apoptosis; Biochemistry","score_opus":0.029121607412445814,"score_gpt":0.40779371399228215,"score_spread":0.37867210657983635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285269469","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9798756,0.007823501,0.011223881,0.00011098952,0.00047574207,0.00035849537,0.00000369337,0.000029750292,0.000098348566],"genre_scores_gemma":[0.8033454,0.00007578718,0.19568905,0.00042433525,0.00007489227,0.00023866374,0.000004586193,0.000027631677,0.00011969637],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99808425,0.0010493798,0.00022997944,0.00030485075,0.00007343873,0.00025808203],"domain_scores_gemma":[0.9995756,0.00009641739,0.000045159002,0.00020588779,0.000011016861,0.00006592213],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00064796617,0.000120717115,0.00028601525,0.00019294911,0.000041706546,0.0000043368555,0.000097340846,0.00007670666,0.00004806085],"category_scores_gemma":[0.000028708773,0.00011717748,0.000054249867,0.0002493387,0.000058593723,0.000012949836,0.0001401959,0.00032368605,0.0000010297227],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012521286,0.0001028827,0.03276587,0.000020131467,0.0000260054,0.00053976517,0.00020225756,0.000042377353,0.88024443,0.00018790949,0.0000017605975,0.085741416],"study_design_scores_gemma":[0.0017932695,0.00047058164,0.018237459,0.000014186624,0.000024157123,0.00009207577,0.0002721166,0.0013879851,0.975033,0.0012945994,0.0012171499,0.00016341651],"about_ca_topic_score_codex":0.000025192845,"about_ca_topic_score_gemma":3.9223113e-7,"teacher_disagreement_score":0.18446517,"about_ca_system_score_codex":0.00007273422,"about_ca_system_score_gemma":0.00004458647,"threshold_uncertainty_score":0.4778359},"labels":[],"label_agreement":null},{"id":"W4285391219","doi":"10.3389/fonc.2022.924290","title":"Autophagy: A Versatile Player in the Progression of Colorectal Cancer and Drug Resistance","year":2022,"lang":"en","type":"review","venue":"Frontiers in Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Sharjah Research Academy; Terry Fox Foundation","keywords":"Autophagy; Cancer research; Tumor microenvironment; Colorectal cancer; Metastasis; Epithelial–mesenchymal transition; Cancer; Immune system; Biology; Tumor progression; Medicine; Immunology; Apoptosis; Internal medicine","score_opus":0.028817400313900687,"score_gpt":0.3840842355874072,"score_spread":0.3552668352735065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285391219","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0019333538,0.99320984,0.0000030177298,0.00020875999,0.0007848054,0.0014619927,0.00004496517,0.000012184421,0.0023411105],"genre_scores_gemma":[0.00021004956,0.99672484,0.00090833346,0.00017936126,0.000069246715,0.0012066634,0.000058419715,0.000028313221,0.00061474217],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99818,0.0005093523,0.00049467606,0.0003343942,0.00023339292,0.00024819875],"domain_scores_gemma":[0.99907666,0.00030348753,0.00032682338,0.00023054163,0.000013339264,0.00004913794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005444304,0.00022493178,0.0015043467,0.00028199016,0.00004490317,0.0000040011614,0.00023660704,0.00024488996,0.00026369607],"category_scores_gemma":[0.00006596549,0.000150854,0.00015214918,0.00043961967,0.00020929222,0.000028022288,0.00007344645,0.0006634308,8.9437833e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000588217,0.0003516004,0.0006371774,0.0040695244,0.00015829799,0.00056600664,0.0023037614,3.9911438e-7,5.6273626e-7,0.000071223054,0.03856582,0.9526874],"study_design_scores_gemma":[0.0013144475,0.00021192792,0.00031257106,0.0025696955,0.00031199594,0.000024493884,0.00041196644,0.000009313721,0.0000033932988,0.00011633959,0.9945922,0.00012166987],"about_ca_topic_score_codex":0.000040694187,"about_ca_topic_score_gemma":0.000105600455,"teacher_disagreement_score":0.9560264,"about_ca_system_score_codex":0.00048186365,"about_ca_system_score_gemma":0.001098423,"threshold_uncertainty_score":0.61516476},"labels":[],"label_agreement":null},{"id":"W4285404940","doi":"10.1016/j.lfs.2022.120800","title":"Rapamycin did not prevent the excessive exercise-induced hepatic fat accumulation","year":2022,"lang":"en","type":"article","venue":"Life Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Fat accumulation; Chemistry; Internal medicine; Endocrinology; Pharmacology; Medicine; Adipose tissue","score_opus":0.06986347645879097,"score_gpt":0.35614899233671465,"score_spread":0.28628551587792367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285404940","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932366,0.00096176955,0.000033687505,0.0038159601,0.00040996182,0.0004948486,0.0000051049615,0.000047489244,0.0009945718],"genre_scores_gemma":[0.99622625,0.000070610506,0.000043827895,0.00281459,0.00015782237,0.00013259912,0.0000060392044,0.0000067105266,0.0005415198],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9985586,0.00011279842,0.0001840411,0.00025200224,0.0006917404,0.00020086441],"domain_scores_gemma":[0.9994125,0.00011268938,0.0001132081,0.0002374788,0.000023154,0.000100971425],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00047505074,0.000094543764,0.0001541163,0.00007063062,0.0008083325,0.000028137953,0.00029277208,0.000019165213,0.0011004689],"category_scores_gemma":[0.00006584653,0.000057713158,0.000081603044,0.00036335943,0.00013616851,0.00012412936,0.00009456718,0.00012917197,0.00004165799],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004033035,0.006293419,0.2056477,0.0005748931,0.0009016937,0.00045424292,0.07104147,0.018835105,0.27967805,0.014190541,0.035483565,0.36286628],"study_design_scores_gemma":[0.006221094,0.0040290244,0.6041819,0.00035402007,0.00078961195,0.00008166191,0.021112476,0.07197373,0.25582728,0.017872281,0.016246017,0.0013108943],"about_ca_topic_score_codex":0.00005584592,"about_ca_topic_score_gemma":0.0000024958385,"teacher_disagreement_score":0.39853418,"about_ca_system_score_codex":0.000036048634,"about_ca_system_score_gemma":0.000197559,"threshold_uncertainty_score":0.99981266},"labels":[],"label_agreement":null},{"id":"W4286262685","doi":"10.1016/j.bbamcr.2022.119325","title":"BNIP3 and Nix: Atypical regulators of cell fate","year":2022,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"","keywords":"Cell fate determination; Cell biology; Computational biology; Biology; Transcription factor; Genetics; Gene","score_opus":0.08222074805807705,"score_gpt":0.3998650034050125,"score_spread":0.31764425534693547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286262685","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15528584,0.8373003,0.0000053367658,0.00017845281,0.000110737696,0.002162784,0.00017416771,0.00007127836,0.0047111227],"genre_scores_gemma":[0.064813614,0.9322287,0.00020451,0.00013020965,0.00016430511,0.00023411283,0.00057694444,0.0002551695,0.0013924595],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9932438,0.0014708821,0.0009475875,0.0013666601,0.0019594708,0.0010115885],"domain_scores_gemma":[0.99633306,0.0005312105,0.0004343187,0.0018340821,0.00019697008,0.0006703573],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001003526,0.00079163874,0.0023047454,0.0008519282,0.00024581785,0.000077769364,0.0008852331,0.0005831944,0.0005074907],"category_scores_gemma":[0.000100967794,0.0006746173,0.0012005965,0.0014916819,0.00078394276,0.00006537489,0.0010042548,0.0021936717,0.000090365764],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016839913,0.005158775,0.000001165966,0.072055355,0.0022603297,0.0017641794,0.00063229416,5.047806e-7,0.7061546,0.0012347205,0.006151832,0.20290229],"study_design_scores_gemma":[0.001404261,0.001335523,0.00003250267,0.0025095409,0.0013152316,0.000038335573,0.000077835546,0.000016150057,0.36433744,0.0002702838,0.62787616,0.00078675884],"about_ca_topic_score_codex":0.000026449827,"about_ca_topic_score_gemma":2.598501e-7,"teacher_disagreement_score":0.6217243,"about_ca_system_score_codex":0.00021322968,"about_ca_system_score_gemma":0.0014776451,"threshold_uncertainty_score":0.9995705},"labels":[],"label_agreement":null},{"id":"W4286500637","doi":"10.1080/27694127.2022.2101335","title":"Evaluating Autophagy in Preimplantation Embryos","year":2022,"lang":"fr","type":"review","venue":"Autophagy Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute; Lawson Health Research Institute; Western University","funders":"","keywords":"Autophagy; Embryo; Cell biology; Andrology; Biology; Medicine; Genetics; Apoptosis","score_opus":0.11607185028924147,"score_gpt":0.43531262582864294,"score_spread":0.31924077553940144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286500637","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03235815,0.9425471,0.000031872572,0.00005770795,0.009701932,0.0044697346,0.000081991435,0.00033147846,0.010420066],"genre_scores_gemma":[0.01227125,0.9598376,0.00053855986,0.0006591715,0.0019857169,0.0023524645,0.002456744,0.00039032818,0.01950817],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9877234,0.0017092718,0.0044040754,0.0023117187,0.002076714,0.0017748313],"domain_scores_gemma":[0.9929112,0.0011565123,0.0028964456,0.0022310403,0.00014969929,0.0006551016],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.004162281,0.001475773,0.003833575,0.00096795295,0.00047889526,0.000115547526,0.00049723807,0.0009373657,0.041535713],"category_scores_gemma":[0.0013457168,0.0015080972,0.0013568464,0.0016977851,0.00022834897,0.00040964162,0.00040420215,0.0022848223,0.000873498],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010873446,0.0010636206,0.00053279113,0.013374516,0.00088522624,0.06482418,0.0008051742,0.00032565344,0.00018958583,0.00049645855,0.00068874145,0.9167053],"study_design_scores_gemma":[0.0025179929,0.0012586128,0.008630073,0.019136032,0.004307017,0.02839908,0.00020709146,0.0025394126,0.0006302372,0.0017136453,0.9287845,0.0018763144],"about_ca_topic_score_codex":0.0003974879,"about_ca_topic_score_gemma":0.00001787598,"teacher_disagreement_score":0.92809576,"about_ca_system_score_codex":0.00223599,"about_ca_system_score_gemma":0.004792109,"threshold_uncertainty_score":0.99990445},"labels":[],"label_agreement":null},{"id":"W4287448568","doi":"10.1016/j.cellsig.2022.110414","title":"Prolonged proteasome inhibition antagonizes TGFβ1-dependent signalling by promoting the lysosomal-targeting of TGFβ receptors","year":2022,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"MG132; Lactacystin; Proteasome; Cell biology; Autophagy; SMAD; Proteasome inhibitor; Smad2 Protein; Transforming growth factor; Chemistry; Signal transduction; Biology; Apoptosis; Biochemistry","score_opus":0.010447157867195894,"score_gpt":0.22496864841913028,"score_spread":0.2145214905519344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4287448568","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98642665,0.007096279,0.0033890447,0.0005963553,0.00023982381,0.0018942034,0.000023408988,0.0001569901,0.00017721602],"genre_scores_gemma":[0.99799776,0.0000702576,0.00038114155,0.00025394757,0.0003193975,0.0003442957,0.00024139773,0.00008755236,0.00030423296],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966644,0.00053288334,0.0008095923,0.00053041434,0.00095019175,0.00051248586],"domain_scores_gemma":[0.99863756,0.00017495832,0.00057007466,0.00030507296,0.00014904914,0.00016330779],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0021554292,0.00030613862,0.00046197703,0.00013453269,0.00080289977,0.000042918695,0.00026155735,0.00010044271,0.00095615967],"category_scores_gemma":[0.00013535877,0.00025047496,0.00027391536,0.00042819284,0.00010932079,0.00013244004,0.00015789976,0.00077391346,0.000012299201],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030432775,0.00039717313,0.0010316216,0.00023005964,0.00018606789,0.00009339827,0.0025237699,0.0009807879,0.99245954,0.000061046456,0.00017100872,0.0015612202],"study_design_scores_gemma":[0.0013655842,0.00048513743,0.000026932345,0.00021544106,0.00018498416,0.000021627195,0.0019609705,0.008072336,0.98609555,0.0003768776,0.0009140949,0.0002804776],"about_ca_topic_score_codex":0.000022964141,"about_ca_topic_score_gemma":3.4502793e-7,"teacher_disagreement_score":0.011571098,"about_ca_system_score_codex":0.00014935405,"about_ca_system_score_gemma":0.00017396704,"threshold_uncertainty_score":0.99999475},"labels":[],"label_agreement":null},{"id":"W4288425593","doi":"10.1007/s11033-022-07708-3","title":"A molecular dialogue between local translation and mitochondria: powering mitophagy in axons","year":2022,"lang":"en","type":"review","venue":"Molecular Biology Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Mitophagy; PINK1; Parkin; Mitochondrion; Translation (biology); Cell biology; Cytosol; Biology; Autophagy; Biochemistry; Apoptosis; Medicine; Gene; Parkinson's disease; Pathology; Messenger RNA; Enzyme","score_opus":0.03808243229429172,"score_gpt":0.3527566792144076,"score_spread":0.3146742469201159,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4288425593","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0044184136,0.9893538,0.0038458207,0.00004805014,0.00042242315,0.0014366799,0.000034481607,0.000066607485,0.0003737463],"genre_scores_gemma":[0.016093092,0.9806827,0.00034221224,0.00018185319,0.00011861468,0.00044176745,0.002000076,0.000110984605,0.000028722427],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9970566,0.0003912299,0.0010114686,0.00091983326,0.00019503896,0.0004258223],"domain_scores_gemma":[0.9986102,0.0001149176,0.00038519784,0.0006681836,0.000020060488,0.00020144814],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003013697,0.00050415663,0.0019615921,0.00042706513,0.0000647446,0.000012256942,0.00010905411,0.0006583194,0.000115002615],"category_scores_gemma":[0.00007842857,0.0004634299,0.0005652541,0.00038870063,0.00020164895,0.0000257712,0.00010169266,0.0007282646,0.000004067656],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023885088,0.000118494434,0.00056810724,0.0021601564,0.00076648564,0.032200765,0.000059182163,0.000003226359,0.0004984,0.000060156355,0.000018648816,0.9635225],"study_design_scores_gemma":[0.0007428904,0.00034265546,0.0001690697,0.0016027779,0.0016695627,0.0035199532,0.000012163279,0.0000056573954,0.00029094162,0.0008576837,0.99018574,0.0006009188],"about_ca_topic_score_codex":0.000048455568,"about_ca_topic_score_gemma":0.0000039084593,"teacher_disagreement_score":0.9901671,"about_ca_system_score_codex":0.0001277184,"about_ca_system_score_gemma":0.0003765113,"threshold_uncertainty_score":0.9997817},"labels":[],"label_agreement":null},{"id":"W4290999099","doi":"10.1016/j.bbrc.2022.08.004","title":"PINK1-dependent and Parkin-independent mitophagy is involved in reprogramming of glycometabolism in pancreatic cancer cells","year":2022,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Japan Society for the Promotion of Science; Yasuda Memorial Medical Foundation; Uehara Memorial Foundation","keywords":"Mitophagy; Parkin; PINK1; Autophagy; Cancer cell; Cell biology; Mitochondrion; Pancreatic cancer; Biology; Glycolysis; Oxidative phosphorylation; Kinase; Cancer research; Cancer; Biochemistry; Metabolism; Apoptosis; Internal medicine; Medicine; Genetics","score_opus":0.06760175492142957,"score_gpt":0.38389812877372637,"score_spread":0.3162963738522968,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4290999099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9813327,0.015438886,0.0000011482059,0.0025737043,0.000014414056,0.0004699161,0.00004482548,0.000010760881,0.00011360037],"genre_scores_gemma":[0.9914342,0.00759974,0.00023053175,0.00015352265,0.000030170202,0.00040892136,0.000026983676,0.000011942055,0.000103969316],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99823034,0.00027960195,0.00032143443,0.00032277417,0.00053891086,0.000306943],"domain_scores_gemma":[0.99856526,0.0003478603,0.000053248998,0.00076816377,0.0000870275,0.00017846245],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005354752,0.00011072886,0.00032608767,0.00021853927,0.00014443263,0.00001640078,0.0003538972,0.000064710104,0.00007344982],"category_scores_gemma":[0.00008336382,0.000098965065,0.000059457685,0.00069972494,0.000493405,0.000036017536,0.000779488,0.00073539006,0.0000017578235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043172328,0.0017812953,0.016981186,0.00012618977,0.00005863247,0.000016730128,0.0006326152,4.871845e-7,0.97102,0.00097503135,0.00013905216,0.007837099],"study_design_scores_gemma":[0.0051652147,0.00069420005,0.19034868,0.00035577567,0.00009505082,0.000010120902,0.0023307914,0.0021394752,0.78728586,0.005458038,0.005730954,0.00038583856],"about_ca_topic_score_codex":0.0014154705,"about_ca_topic_score_gemma":0.000047105306,"teacher_disagreement_score":0.1837341,"about_ca_system_score_codex":0.0001037201,"about_ca_system_score_gemma":0.00013801639,"threshold_uncertainty_score":0.40356782},"labels":[],"label_agreement":null},{"id":"W4291594995","doi":"10.1016/j.mce.2022.111753","title":"Oleate restores altered autophagic flux to rescue palmitate lipotoxicity in hypothalamic neurons","year":2022,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Lipotoxicity; Flux (metallurgy); Lipid metabolism; Programmed cell death; Cell biology; Biology; Endocrinology; Diacylglycerol kinase; Lipid droplet; Internal medicine; Chemistry; Biochemistry; Signal transduction; Apoptosis; Medicine; Insulin resistance","score_opus":0.012988355804925631,"score_gpt":0.2514786188281119,"score_spread":0.23849026302318627,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4291594995","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99328685,0.002957108,0.00018867913,0.0014027366,0.00024614352,0.00058198033,0.000017055267,0.00008976695,0.0012296963],"genre_scores_gemma":[0.9951043,0.000054315635,0.00018150947,0.003163682,0.00004926138,0.000194224,0.00005695728,0.000046552614,0.0011492138],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997976,0.00031506797,0.0003011507,0.0005665186,0.00023641523,0.0006048525],"domain_scores_gemma":[0.999191,0.000031178435,0.000042099688,0.0005045417,0.000021070013,0.00021012433],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010492225,0.00023376009,0.00039425085,0.00034090818,0.00015189072,0.000013202209,0.00018597435,0.000052692234,0.00036860158],"category_scores_gemma":[0.000035769677,0.00024563362,0.00012090987,0.00027230586,0.00009324388,0.000027541004,0.00028357684,0.00045581476,0.000041594973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051864656,0.00034853435,0.006128998,0.000041885727,0.000099952464,0.012736479,0.00037425544,0.0005109436,0.9738374,0.0016066113,0.0002711242,0.0035252054],"study_design_scores_gemma":[0.005085642,0.0018120182,0.08350633,0.000026860123,0.00013550841,0.0012315147,0.00022971595,0.0005120595,0.8841505,0.0023553246,0.020435825,0.0005186711],"about_ca_topic_score_codex":0.00012698132,"about_ca_topic_score_gemma":0.000014384264,"teacher_disagreement_score":0.08968683,"about_ca_system_score_codex":0.00008000555,"about_ca_system_score_gemma":0.000081845676,"threshold_uncertainty_score":0.9999996},"labels":[],"label_agreement":null},{"id":"W4292595710","doi":"10.1152/ajpregu.00110.2022","title":"Autophagic response to exercise in peripheral blood mononuclear cells from young men is intensity-dependent and is altered by exposure to environmental heat","year":2022,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Peripheral blood mononuclear cell; Autophagy; Internal medicine; Heat shock protein; Heat shock; Exercise intensity; Intensity (physics); Endocrinology; VO2 max; Medicine; Inflammation; Aerobic exercise; Apoptosis; Chemistry; Heart rate; Blood pressure; Biochemistry","score_opus":0.009495002616947815,"score_gpt":0.25229512300965373,"score_spread":0.24280012039270593,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4292595710","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967693,0.0015516498,0.000018351062,0.00074395095,0.00013485244,0.00047232027,0.00027851283,0.0000115296225,0.000019526246],"genre_scores_gemma":[0.9952478,0.00019967004,0.00027556546,0.003875087,0.00009848482,0.00005749241,0.000023829953,0.000027300533,0.00019479619],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9973291,0.00076569157,0.0005864649,0.00065670663,0.0002765451,0.0003855018],"domain_scores_gemma":[0.9987361,0.0001455293,0.0003104181,0.00032907934,0.00008354611,0.00039532036],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021028768,0.00043574034,0.0015166373,0.0002452122,0.00019728423,0.000014997359,0.00024943438,0.00006365236,0.00069315464],"category_scores_gemma":[0.000008165067,0.00035101018,0.00017919572,0.00021831888,0.00065541314,0.00011082325,0.0002435811,0.00063819956,0.000011875478],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02192671,0.0006294198,0.0013323077,0.000004789991,0.00051149813,0.000027940841,0.02873012,0.00015281478,0.94223094,0.000006802864,0.003908104,0.0005385228],"study_design_scores_gemma":[0.0041417694,0.01689819,0.6416819,0.00011017269,0.00018741043,0.000097681244,0.051557645,0.00030477415,0.28338683,0.00054813083,0.0006006685,0.0004848103],"about_ca_topic_score_codex":0.00023587825,"about_ca_topic_score_gemma":0.000004361197,"teacher_disagreement_score":0.6588442,"about_ca_system_score_codex":0.00019252498,"about_ca_system_score_gemma":0.00009682155,"threshold_uncertainty_score":0.9998942},"labels":[],"label_agreement":null},{"id":"W4293021162","doi":"","title":"L’effet pro-migratoire des RCPG chimiotactiques nécessite la modulation de l’autophagie via la voie calpaïne/ATG5: rôle potentiel dans l’invasion des cellules de gliome","year":2015,"lang":"fr","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Physics","score_opus":0.018909186719215123,"score_gpt":0.2608868792009593,"score_spread":0.2419776924817442,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293021162","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81144243,0.013206764,0.15157296,0.0019147614,0.00037542067,0.0010367406,0.00017098033,0.0005186812,0.01976124],"genre_scores_gemma":[0.9452183,0.0074793966,0.031274416,0.00012347974,0.00019424253,0.00022319288,0.0011975918,0.00019638406,0.014092954],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9828006,0.012554979,0.0010936144,0.0013192745,0.00090720574,0.0013243075],"domain_scores_gemma":[0.99081165,0.001998529,0.00094215566,0.0025358207,0.0025977069,0.0011141232],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.010440371,0.0009509188,0.0009779698,0.0004896073,0.0011677331,0.0006141542,0.0014104797,0.0011476774,0.0002540332],"category_scores_gemma":[0.0020258636,0.0009811862,0.0005705994,0.00089427346,0.0017875133,0.0005718487,0.00101404,0.0014033939,0.00009478115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006280709,0.008195125,0.109995514,0.0036683958,0.0014049904,0.000679721,0.0922948,0.0023399687,0.41785622,0.055764146,0.0018687006,0.30530435],"study_design_scores_gemma":[0.0034802859,0.000012254512,0.22474651,0.012674049,0.0008317757,0.00045858102,0.0014432289,0.14826278,0.52978384,0.06465382,0.012099264,0.0015535943],"about_ca_topic_score_codex":0.0042430987,"about_ca_topic_score_gemma":0.0017665455,"teacher_disagreement_score":0.30375075,"about_ca_system_score_codex":0.0013717605,"about_ca_system_score_gemma":0.0017343004,"threshold_uncertainty_score":0.9992639},"labels":[],"label_agreement":null},{"id":"W4293052036","doi":"10.1128/mcb.00241-22","title":"Invading Bacterial Pathogens Activate Transcription Factor EB in Epithelial Cells through the Amino Acid Starvation Pathway of mTORC1 Inhibition","year":2022,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"TFEB; Biology; Innate immune system; Transcription factor; Autophagy; Cell biology; mTORC1; Effector; Transcriptome; Basic helix-loop-helix leucine zipper transcription factors; Caenorhabditis elegans; Signal transduction; Microbiology; Immune system; Gene; Immunology; Genetics; Gene expression; DNA-binding protein; PI3K/AKT/mTOR pathway","score_opus":0.014627997203983526,"score_gpt":0.23049281648657316,"score_spread":0.21586481928258963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293052036","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942579,0.00049125636,0.0042067897,0.00014077246,0.00026619283,0.00037618662,0.00018070826,0.000014252057,0.0000659161],"genre_scores_gemma":[0.99897414,0.00006610162,0.00004772347,0.00035279372,0.00006386738,0.000044501,0.00041249525,0.000015629741,0.000022734717],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891347,0.0003252751,0.0002479884,0.00022541736,0.0001134499,0.00017442262],"domain_scores_gemma":[0.9996613,0.000019796855,0.000098953235,0.00016322065,0.000023267303,0.00003346435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016055546,0.00012553018,0.00021695363,0.00006777022,0.000097941855,0.0000060686757,0.000052772153,0.00008874093,0.00023611741],"category_scores_gemma":[0.000009556782,0.000098933844,0.000093612805,0.00013029936,0.00008550587,0.000043881973,0.00003504665,0.00017681703,0.0000015766009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041684663,0.00011659041,0.00022363846,0.00002464426,0.000038589194,0.000048866794,0.0013238939,0.000010816968,0.994767,0.0014025645,0.0000037218142,0.0016228216],"study_design_scores_gemma":[0.0014306357,0.0004940131,0.00094666827,0.000009955214,0.000033445514,0.000008879303,0.00028855298,0.000037018428,0.9926274,0.001737186,0.002290158,0.000096105374],"about_ca_topic_score_codex":0.000054639382,"about_ca_topic_score_gemma":0.0000030864646,"teacher_disagreement_score":0.0047162273,"about_ca_system_score_codex":0.000043282456,"about_ca_system_score_gemma":0.000050650364,"threshold_uncertainty_score":0.4034405},"labels":[],"label_agreement":null},{"id":"W4293280680","doi":"10.1093/nsr/nwac174","title":"Hologenomic insights into mammalian adaptations to myrmecophagy","year":2022,"lang":"en","type":"article","venue":"National Science Review","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Royal Ontario Museum","funders":"Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Biology; Evolutionary biology; Zoology","score_opus":0.034962667764271094,"score_gpt":0.3665274347690276,"score_spread":0.3315647670047565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293280680","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.628327,0.2914451,0.00042650194,0.04159376,0.0007402135,0.002957087,0.00004055555,0.00014368497,0.03432611],"genre_scores_gemma":[0.97106785,0.00438421,0.0010575153,0.02250259,0.00006787121,0.00023706371,0.000024126959,0.000006228647,0.00065251853],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99849284,0.0000390694,0.00018612038,0.0002512168,0.00088583364,0.00014493914],"domain_scores_gemma":[0.99937135,0.000027947613,0.000052065356,0.00015141844,0.00021030792,0.00018691055],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006034109,0.00006743424,0.00014134018,0.00018020217,0.000482702,0.000010730128,0.00024157934,0.000009445687,0.0020438232],"category_scores_gemma":[0.00021020955,0.000057984555,0.00006227571,0.0013691201,0.00009143561,0.00010002943,0.000089883826,0.00008890582,0.00032135446],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013985448,0.0015405901,0.0011660493,0.0012783282,0.00013805137,0.0002168753,0.002636106,0.00093437044,0.14177395,0.40938905,0.05983648,0.38095027],"study_design_scores_gemma":[0.0005503603,0.0003691395,0.0702093,0.00032476085,0.00007246656,0.00011007866,0.00008421226,0.00020230938,0.0016078885,0.011679674,0.91454095,0.00024883595],"about_ca_topic_score_codex":0.000009329927,"about_ca_topic_score_gemma":0.000002142191,"teacher_disagreement_score":0.8547045,"about_ca_system_score_codex":0.00041278513,"about_ca_system_score_gemma":0.0011079954,"threshold_uncertainty_score":0.99886847},"labels":[],"label_agreement":null},{"id":"W4293428122","doi":"10.1080/15548627.2022.2117973","title":"LEAP: a novel LC3C-dependent pathway connects autophagy, endocytic trafficking and signaling","year":2022,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Biology; Endocytic cycle; Cell biology; Signal transduction; Endosome; Endocytosis; Genetics; Apoptosis; Receptor; Intracellular","score_opus":0.01944956364609248,"score_gpt":0.2548580553303022,"score_spread":0.23540849168420971,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293428122","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99077755,0.0050414847,0.00057342486,0.00030156248,0.00054151774,0.00069101196,0.00006130785,0.0004223234,0.0015898276],"genre_scores_gemma":[0.9943617,0.00005177259,0.00040514456,0.002626036,0.00026937545,0.00018702584,0.00005450039,0.00008737837,0.0019570629],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974118,0.00010825819,0.0004750305,0.00068426767,0.0006915957,0.00062906224],"domain_scores_gemma":[0.9987108,0.00022622044,0.00017797518,0.00048388922,0.000060929175,0.0003401478],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00041188303,0.0003604325,0.0005656866,0.00023709814,0.00055998587,0.00006008471,0.00022396755,0.00009556741,0.0017381285],"category_scores_gemma":[0.00007959833,0.00036160275,0.00020145647,0.00031249857,0.00011259341,0.00013648895,0.00023129556,0.0005541399,0.00004489293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013448732,0.0025571012,0.0006075112,0.00041141734,0.0010940974,0.0059877816,0.0072209765,0.0025187838,0.9036276,0.022464374,0.00051696325,0.051648553],"study_design_scores_gemma":[0.039529227,0.0044068196,0.015896374,0.0003471093,0.0010361553,0.0070813093,0.0056361286,0.029703807,0.84263813,0.0031293884,0.04817139,0.002424166],"about_ca_topic_score_codex":0.000044334265,"about_ca_topic_score_gemma":0.0000026093028,"teacher_disagreement_score":0.06098944,"about_ca_system_score_codex":0.0002468291,"about_ca_system_score_gemma":0.00039268783,"threshold_uncertainty_score":0.9998836},"labels":[],"label_agreement":null},{"id":"W4293578872","doi":"10.1016/j.atherosclerosis.2022.06.453","title":"Autophagy is differentially regulated in leukocyte and nonleukocyte foam cells during atherosclerosis","year":2022,"lang":"en","type":"article","venue":"Atherosclerosis","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Foam cell; Autophagy; Cell biology; Lipid droplet; Catabolism; Macrophage; Cytosol; Vascular smooth muscle; Cholesterol; Efflux; Chemistry; Cell; Smooth muscle; Lipoprotein; Biology; Biochemistry; Endocrinology; Metabolism; Apoptosis; In vitro","score_opus":0.01207854823209495,"score_gpt":0.22718649427898313,"score_spread":0.21510794604688818,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293578872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99713355,0.0007722088,0.000020233494,0.00042682726,0.00028286283,0.00073416636,0.00007400465,0.0002374881,0.0003186751],"genre_scores_gemma":[0.99391866,0.0009506677,0.00019748481,0.0015354092,0.00010042375,0.00026078057,0.000030843617,0.00013897532,0.0028667354],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99697655,0.0001764957,0.0006163562,0.00086158334,0.00064002554,0.00072900095],"domain_scores_gemma":[0.9986152,0.00006519409,0.00020256238,0.0007518993,0.000049055234,0.0003160684],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002595939,0.00046557846,0.00070816797,0.00029736888,0.0005037181,0.000069170805,0.00029271826,0.00016175183,0.0023694006],"category_scores_gemma":[0.000012643034,0.0004729964,0.00027460183,0.000634229,0.00015661168,0.00016255035,0.00037190397,0.0005386111,0.000051440835],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006929978,0.00082947465,0.03262558,0.00011080079,0.00024139229,0.00003968988,0.0026809745,0.00006164143,0.9602693,0.000096063086,0.00040233636,0.0019497762],"study_design_scores_gemma":[0.006202844,0.00039926634,0.63070273,0.000121100944,0.0001312606,0.000025548277,0.0002533877,0.0007297962,0.36005768,0.00013444023,0.00081197004,0.0004300019],"about_ca_topic_score_codex":0.00021855837,"about_ca_topic_score_gemma":0.000014877378,"teacher_disagreement_score":0.6002116,"about_ca_system_score_codex":0.00039756575,"about_ca_system_score_gemma":0.00012172257,"threshold_uncertainty_score":0.9997722},"labels":[],"label_agreement":null},{"id":"W4294176661","doi":"10.3389/fimmu.2022.934819","title":"Prototheca bovis induces autophagy in bovine mammary epithelial cells via the HIF-1α and AMPKα/ULK1 pathway","year":2022,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Natural Science Foundation of Ningxia Province; National Natural Science Foundation of China","keywords":"Autophagy; AMPK; Western blot; Cell biology; PI3K/AKT/mTOR pathway; Chemistry; Biology; Protein kinase A; Molecular biology; Apoptosis; Kinase; Signal transduction; Biochemistry","score_opus":0.006851991125171005,"score_gpt":0.22222773230566906,"score_spread":0.21537574118049804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4294176661","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9786626,0.014931718,0.0005596852,0.002018404,0.001643043,0.0014910754,0.000034967863,0.00006762397,0.0005909002],"genre_scores_gemma":[0.99453807,0.0008094862,0.000853805,0.001457644,0.00011133584,0.00076853076,0.000031566007,0.00004222016,0.0013873198],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99812907,0.00040308584,0.00040046388,0.0004069124,0.00020022952,0.0004602215],"domain_scores_gemma":[0.99919534,0.0000665523,0.00012848366,0.0005329115,0.000020158368,0.00005657462],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043752408,0.00022955672,0.0004841355,0.00035902945,0.00019072974,0.00001548546,0.00037399805,0.00015116336,0.00028397195],"category_scores_gemma":[0.000031574007,0.00018411432,0.000083947765,0.00043941053,0.00030129417,0.00009743766,0.00028871643,0.0007890244,0.000009854416],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0118239,0.0032231945,0.030695636,0.00023656667,0.0013999369,0.003940917,0.019734478,0.000064094434,0.45845684,0.003822561,0.014134118,0.45246777],"study_design_scores_gemma":[0.026079359,0.006609549,0.41090956,0.00014328877,0.00017521682,0.0008389624,0.006988581,0.002570435,0.22228327,0.043273743,0.27863652,0.0014915031],"about_ca_topic_score_codex":0.00021107735,"about_ca_topic_score_gemma":0.000011581571,"teacher_disagreement_score":0.45097625,"about_ca_system_score_codex":0.00019831167,"about_ca_system_score_gemma":0.00022145233,"threshold_uncertainty_score":0.75079644},"labels":[],"label_agreement":null},{"id":"W4295309180","doi":"10.15252/rc.2022851768","title":"Author Reply to Peer Reviews of AI-guided screen identifies probucol-mediated mitophagy enhancement through modulation of lipid droplets","year":2022,"lang":"en","type":"peer-review","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Toronto Western Hospital","funders":"","keywords":"Probucol; Modulation (music); Mitophagy; Nanotechnology; Materials science; Chemistry; Art; Biochemistry; Aesthetics; Autophagy; Cholesterol","score_opus":0.07494012015843822,"score_gpt":0.3929431107216515,"score_spread":0.3180029905632133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4295309180","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008087514,0.37864098,0.008088078,0.49478543,0.0124892965,0.048408635,0.0034591442,0.0005565738,0.045484368],"genre_scores_gemma":[0.0015147595,0.035663974,0.0031225462,0.03796348,0.0009638842,0.001762482,0.01148882,0.00015741978,0.90736264],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9932977,0.0003822069,0.002806867,0.000922668,0.00216302,0.00042755817],"domain_scores_gemma":[0.9948918,0.000118909964,0.0014698692,0.0017459508,0.0015375711,0.00023587745],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0017774389,0.00062739005,0.0028157802,0.00031204722,0.00008903463,0.00001576889,0.0004799083,0.00024716984,0.040444832],"category_scores_gemma":[0.0015025918,0.0005115382,0.00083330384,0.0009037814,0.000098239354,0.00014544191,0.0002791789,0.0005354103,0.00016507626],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016773172,0.0004919111,0.00002592177,0.011747798,0.00049087853,0.000016752812,0.00031008225,0.0000056403974,0.0060714004,0.000112166395,0.9773269,0.0032327739],"study_design_scores_gemma":[0.00097572134,0.00065604557,0.0003722046,0.00662238,0.00080731,0.0000096156355,0.000029687939,0.000031115847,0.016837567,0.00012911107,0.9731268,0.00040240923],"about_ca_topic_score_codex":0.00072769984,"about_ca_topic_score_gemma":0.000025536234,"teacher_disagreement_score":0.8618783,"about_ca_system_score_codex":0.00022441581,"about_ca_system_score_gemma":0.00061140704,"threshold_uncertainty_score":0.9997336},"labels":[],"label_agreement":null},{"id":"W4296764616","doi":"10.3390/v14092026","title":"Coxsackievirus Protease 2A Targets Host Protease ATG4A to Impair Autophagy","year":2022,"lang":"en","type":"article","venue":"Viruses","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC; Faculty of Medicine, University of British Columbia; Natural Sciences and Engineering Research Council of Canada; St. Paul's Foundation","keywords":"Autophagy; Protease; Coxsackievirus; Cell biology; Biology; Proteases; Gene silencing; Cleavage (geology); Cysteine protease; Virology; Virus; Biochemistry; Enzyme; Gene; Apoptosis; Enterovirus","score_opus":0.026259790126902393,"score_gpt":0.3085432128560583,"score_spread":0.2822834227291559,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4296764616","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98877335,0.0037332512,0.00009674616,0.001234043,0.00038758037,0.0036296088,0.00037296512,0.00051945803,0.0012530162],"genre_scores_gemma":[0.97126913,0.00004834226,0.000507296,0.023133902,0.00041331488,0.0023791308,0.00004986164,0.00009536458,0.0021036388],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976995,0.0001685367,0.00037570193,0.0005451374,0.0006617466,0.00054934906],"domain_scores_gemma":[0.99837095,0.000048932776,0.00011924844,0.0007289212,0.00008100445,0.00065094646],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00029171866,0.00031838403,0.0004271425,0.0002287316,0.00044406607,0.00003606631,0.00028447152,0.000064258296,0.006089816],"category_scores_gemma":[0.00016814416,0.00029136668,0.00020546764,0.00050314737,0.000073668656,0.00014657927,0.0002504359,0.00036955814,0.00090031984],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.016844641,0.010062524,0.036249503,0.0008229458,0.001417622,0.009329361,0.004642233,0.00036391296,0.71606743,0.0036106056,0.16252695,0.03806225],"study_design_scores_gemma":[0.0038112735,0.002431775,0.03325684,0.00007989151,0.00017225042,0.00009686604,0.00029452197,0.00014174939,0.29239815,0.00039379255,0.666286,0.0006369067],"about_ca_topic_score_codex":0.00023801175,"about_ca_topic_score_gemma":0.0000030032604,"teacher_disagreement_score":0.503759,"about_ca_system_score_codex":0.00020662395,"about_ca_system_score_gemma":0.00045004042,"threshold_uncertainty_score":0.99995387},"labels":[],"label_agreement":null},{"id":"W4297806077","doi":"10.5281/zenodo.3350283","title":"The Expression of Beclin-1 in Hepatocellular Carcinoma and Non-Tumor Liver Tissue: A Meta-Analysis","year":2018,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Hepatocellular carcinoma; Liver tissue; Carcinoma; Pathology; Medicine; Oncology; Cancer research; Internal medicine; Biology","score_opus":0.05436869600521228,"score_gpt":0.28224703841885873,"score_spread":0.22787834241364646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297806077","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98690736,0.0017482046,0.0006380249,0.00035975827,0.000019174673,0.00050237455,0.000052744752,0.00008100723,0.009691338],"genre_scores_gemma":[0.998643,0.000115648494,0.00011182684,0.000107110856,0.00005409518,8.362642e-8,0.000098238765,0.0002189699,0.00065102725],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99883765,0.00020526421,0.00024101303,0.0002533767,0.00027392354,0.00018879565],"domain_scores_gemma":[0.99898374,0.000033373923,0.00009838263,0.0004408298,0.00032630103,0.00011735719],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005488042,0.000099127974,0.00029634702,0.00019341303,0.0006293306,0.00008920646,0.00027985979,0.000034972898,0.0065369853],"category_scores_gemma":[0.00016000748,0.00006885054,0.00012478833,0.000569977,0.00026421002,0.0000736277,0.00032428213,0.000121254816,0.00041389803],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005922276,0.0032385108,0.0077714096,0.0010564226,0.048276916,0.0015625926,0.029961055,0.000034868794,0.6697997,0.0065607643,0.12215847,0.10365705],"study_design_scores_gemma":[0.0027491914,0.0016845964,0.052627087,0.000038745187,0.016311036,0.00012730248,0.00088032795,0.0046087545,0.22982861,0.0003015198,0.6904623,0.00038055098],"about_ca_topic_score_codex":0.00004298441,"about_ca_topic_score_gemma":9.09756e-7,"teacher_disagreement_score":0.5683038,"about_ca_system_score_codex":0.000028645703,"about_ca_system_score_gemma":0.0000045135876,"threshold_uncertainty_score":0.9943712},"labels":[],"label_agreement":null},{"id":"W4298328825","doi":"10.17615/v5y9-k642","title":"Variants in autophagy-related genes and clinical characteristics in melanoma: a population-based study","year":2020,"lang":"en","type":"article","venue":"UNC Libraries","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"BC Cancer Agency; University of California, Irvine; National Cancer Institute; University of North Carolina at Chapel Hill; National Institutes of Health; Menzies Institute for Medical Research; Cancer Care Ontario; Missouri Department of Health and Senior Services; University of Tasmania; University of Pennsylvania; State of New Jersey Department of Health","keywords":"Autophagy; Gene; Melanoma; Genetics; Biology; Population; Computational biology; Medicine; Environmental health","score_opus":0.030237810795297092,"score_gpt":0.2974324150984076,"score_spread":0.26719460430311054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4298328825","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973321,0.000619625,0.00001981521,0.0012399687,0.00010471731,0.0004763792,0.000012226437,0.000078829034,0.00011633809],"genre_scores_gemma":[0.9977314,0.000011945681,0.0005093311,0.0014784975,0.00009897609,0.000013405272,0.000076916236,0.000020369524,0.000059192673],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987623,0.00012810652,0.0005444689,0.00027892963,0.00013330362,0.00015289643],"domain_scores_gemma":[0.9994278,0.00017132483,0.0000832317,0.00015684772,0.0000139467165,0.00014685332],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013943888,0.00013515352,0.00042281154,0.000092279726,0.00003150888,0.0000378768,0.00006661232,0.00011206717,0.00019183337],"category_scores_gemma":[0.00021231215,0.0001178199,0.000042936892,0.0002723402,0.000045710563,0.00016323905,0.000036386802,0.00020195747,0.000016247972],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005112817,0.00061698246,0.9928735,0.000031811644,0.00005714388,0.0004544874,0.00080216787,0.0000027205965,0.00002991419,0.002154033,0.000023392535,0.002442579],"study_design_scores_gemma":[0.004509821,0.00047528266,0.98916155,0.000042200645,0.000050150335,0.0000014380468,0.00014528682,0.0036104692,0.00006711486,0.0017655649,0.00006155288,0.00010954066],"about_ca_topic_score_codex":0.000049936796,"about_ca_topic_score_gemma":0.000013790794,"teacher_disagreement_score":0.0039985394,"about_ca_system_score_codex":0.000013532522,"about_ca_system_score_gemma":0.0001686697,"threshold_uncertainty_score":0.4804556},"labels":[],"label_agreement":null},{"id":"W4299897268","doi":"","title":"Nanoparticles and Viruses as Mitophagy Inducers in Immune Cells","year":2017,"lang":"en","type":"book-chapter","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Mitophagy; Immune system; Inducer; Nanoparticle; Virology; Cell biology; Nanotechnology; Autophagy; Biology; Materials science; Immunology; Biochemistry; Apoptosis","score_opus":0.017814437362048227,"score_gpt":0.2516783743905506,"score_spread":0.23386393702850233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4299897268","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3897039,0.011805574,0.000052828444,0.0025340857,0.00016641383,0.0005788962,0.00003488032,0.00011576988,0.59500766],"genre_scores_gemma":[0.63206017,0.0042258226,0.0009119531,0.0003480196,0.000034546978,0.000022673743,0.0000791153,0.00007623523,0.36224145],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982085,0.00039466133,0.0003950779,0.00047241288,0.0002824347,0.00024687318],"domain_scores_gemma":[0.99715006,0.00040180745,0.00034314772,0.0014814828,0.00041960657,0.0002039154],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011316303,0.00029018012,0.0004562618,0.00018059248,0.00021872106,0.00012722913,0.00038239235,0.00028249496,0.00051404134],"category_scores_gemma":[0.00028575514,0.00029049223,0.00014436168,0.000035545974,0.0003819824,0.00011171739,0.00022127044,0.00039175368,0.0001473187],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038527677,0.001239727,0.0024327312,0.0005157761,0.00070968946,0.0005252686,0.011318567,0.0000016358954,0.34148347,0.40331748,0.0016106137,0.23645976],"study_design_scores_gemma":[0.0026726115,0.0000035520814,0.007993778,0.0044541317,0.00017250277,0.00005195673,0.00007040464,0.00011370467,0.82414865,0.017247567,0.14244176,0.0006293616],"about_ca_topic_score_codex":0.00052456866,"about_ca_topic_score_gemma":0.00031862757,"teacher_disagreement_score":0.48266518,"about_ca_system_score_codex":0.00007060304,"about_ca_system_score_gemma":0.00023922652,"threshold_uncertainty_score":0.9999547},"labels":[],"label_agreement":null},{"id":"W4300818475","doi":"10.1016/j.bbrep.2022.101358","title":"Potential role of TGFΒ and autophagy in early cerebellum development","year":2022,"lang":"en","type":"article","venue":"Biochemistry and Biophysics Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Research Manitoba","keywords":"Cell biology; Cerebellum; Biology; Autophagy; Signal transduction; Neurogenesis; Downregulation and upregulation; Transforming growth factor; Transforming growth factor beta; Embryonic stem cell; Neuroscience; Genetics; Apoptosis","score_opus":0.0035798816643415896,"score_gpt":0.2091950912656648,"score_spread":0.2056152096013232,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4300818475","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978768,0.0014175355,0.0000023208722,0.000027528575,0.00004330558,0.00010284701,0.0000060044886,0.000013637934,0.00050998584],"genre_scores_gemma":[0.99931157,0.00003380294,0.000109138644,0.000040201874,0.0000471615,0.000018211382,0.00003672907,0.000008193584,0.00039498432],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992222,0.000008563463,0.00023846426,0.00023176675,0.00018130618,0.000117696654],"domain_scores_gemma":[0.9996212,0.0000047418566,0.00011614472,0.00015696915,0.00002412027,0.00007684062],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007991913,0.00009643291,0.00017215469,0.000027256609,0.0000690675,0.0000059588933,0.000026178335,0.000041431253,0.00003482469],"category_scores_gemma":[0.000004830493,0.000094763804,0.00003426978,0.00009746209,0.000060775223,0.000020906684,0.00009158769,0.00009964678,2.2869656e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009231962,0.00029542242,0.022002682,0.00010327256,0.000052259245,0.0006469335,0.0003355296,0.0000016058237,0.96930575,0.000022303655,0.000021461037,0.007120455],"study_design_scores_gemma":[0.00041108497,0.000062012514,0.082965255,0.000022242182,0.000024114182,0.00031063988,0.00018483767,0.000025910247,0.9147837,0.0005243687,0.0005826556,0.000103135884],"about_ca_topic_score_codex":0.000026648995,"about_ca_topic_score_gemma":1.11505905e-7,"teacher_disagreement_score":0.06096257,"about_ca_system_score_codex":0.000025181229,"about_ca_system_score_gemma":0.00013953057,"threshold_uncertainty_score":0.38643557},"labels":[],"label_agreement":null},{"id":"W4303613937","doi":"10.3390/biomedicines10102443","title":"FYCO1 Increase and Effect of Arimoclomol–Treatment in Human VCP–Pathology","year":2022,"lang":"en","type":"article","venue":"Biomedicines","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Manitoba; Research Manitoba","funders":"French Muscular Dystrophy Association; Ministerium für Kultur und Wissenschaft des Landes Nordrhein-Westfalen; European Regional Development Fund; Universität Duisburg-Essen; Bundesministerium für Bildung und Forschung; Association Française contre les Myopathies","keywords":"Immunostaining; Cell biology; Biology; Cancer research; Context (archaeology); Pathology; Autophagy; Signal transducing adaptor protein; Ubiquitin; Medicine; Immunohistochemistry; Signal transduction; Biochemistry; Apoptosis; Gene","score_opus":0.008309026159706103,"score_gpt":0.30340887542417316,"score_spread":0.2950998492644671,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4303613937","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947313,0.0037237168,0.0000013024923,0.00034721734,0.00011058415,0.0004063893,0.000016892101,0.00002569381,0.00063687185],"genre_scores_gemma":[0.9989772,0.00011133375,0.000016979506,0.00025165154,0.00010217791,0.000112149246,0.00007215263,0.000012728098,0.00034365657],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9991764,0.0001285483,0.00020483577,0.00019173966,0.00015222956,0.00014628196],"domain_scores_gemma":[0.9995336,0.00009179351,0.000061697196,0.00020563458,0.000012421538,0.00009487995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023395583,0.00012526989,0.00039000207,0.00026572752,0.00006289754,0.000001323155,0.000047381815,0.000036268782,0.0003148671],"category_scores_gemma":[0.000027255199,0.00008820792,0.000047833837,0.00021562935,0.00016405556,0.0000144233,0.00004792579,0.000072087074,0.0000018470244],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00196598,0.0011422606,0.66622794,0.00032897622,0.0002143409,0.003530672,0.0015084655,0.0000015547379,0.3019736,0.0003712259,0.00082974194,0.021905249],"study_design_scores_gemma":[0.023881648,0.023736145,0.8804682,0.00014607761,0.00050925533,0.00089530356,0.00057602604,0.000068297464,0.056937866,0.0006183105,0.011892476,0.00027039202],"about_ca_topic_score_codex":0.00047055032,"about_ca_topic_score_gemma":0.000007719066,"teacher_disagreement_score":0.24503574,"about_ca_system_score_codex":0.00006391466,"about_ca_system_score_gemma":0.00004697797,"threshold_uncertainty_score":0.35970145},"labels":[],"label_agreement":null},{"id":"W4304761866","doi":"10.3390/cells11203203","title":"Analysis of the Compositional Features and Codon Usage Pattern of Genes Involved in Human Autophagy","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"King Saud University","keywords":"Gene; Autophagy; Biology; Codon usage bias; Genome; Genetics; Human genome; GC-content; Start codon; Computational biology; Nucleotide","score_opus":0.012251800815089782,"score_gpt":0.2648347048223579,"score_spread":0.25258290400726807,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4304761866","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981431,0.0013634701,0.0000099875415,0.00006914462,0.000034681794,0.00011057413,0.00007675575,0.0000040572045,0.00018827901],"genre_scores_gemma":[0.99933416,0.00002327343,0.000009961866,0.00034574277,0.000012710867,0.000007389041,0.000053186624,0.0000046819714,0.00020889327],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99945533,0.00006930114,0.00014529235,0.00009528807,0.00017341542,0.000061380815],"domain_scores_gemma":[0.999688,0.000034775963,0.000076982,0.00015996705,0.000016773804,0.000023463896],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008775214,0.000052009014,0.00020282886,0.00012102261,0.000049959053,0.0000019690283,0.0000729688,0.000019187626,0.0005114882],"category_scores_gemma":[0.0000011922933,0.000039236314,0.00009688549,0.00027266642,0.00007025895,0.000010321644,0.000058785252,0.00007683953,1.879849e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006245205,0.0003181692,0.22467554,0.00005543703,0.00047980665,0.0000159741,0.0008214902,0.00048856204,0.7719843,0.00011290995,0.00023316624,0.000752219],"study_design_scores_gemma":[0.00056993647,0.00006348923,0.72306776,0.000011438786,0.0002858947,0.0000012167918,0.0001352614,0.00035018282,0.27531946,0.000065060005,0.000097631,0.000032691572],"about_ca_topic_score_codex":0.00014783752,"about_ca_topic_score_gemma":0.000029575753,"teacher_disagreement_score":0.4983922,"about_ca_system_score_codex":0.00001756302,"about_ca_system_score_gemma":0.000021483254,"threshold_uncertainty_score":0.5600437},"labels":[],"label_agreement":null},{"id":"W4306249880","doi":"10.1139/gen-2022-0069","title":"Autophagy in cell fate decisions: knowledge gained from<i>Drosophila</i>","year":2022,"lang":"en","type":"review","venue":"Genome","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Université de Sherbrooke","keywords":"Autophagy; Biology; Cell biology; Cell fate determination; Programmed cell death; Progenitor cell; Stem cell; Homeostasis; Cell; Cellular differentiation; Signal transduction; Genetics; Apoptosis; Transcription factor; Gene","score_opus":0.07255119035963159,"score_gpt":0.346762615522056,"score_spread":0.2742114251624244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4306249880","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00026526517,0.9850264,0.000008284326,0.000026239451,0.0005793275,0.0013863276,0.00040034865,0.00012452457,0.01218324],"genre_scores_gemma":[0.00009810846,0.99084914,0.00016176939,0.0003694293,0.0008648885,0.00051507406,0.0018721073,0.0001658743,0.0051036295],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969996,0.00027278336,0.0009838678,0.00084155344,0.00036471453,0.00053744076],"domain_scores_gemma":[0.99765664,0.0005361438,0.00029919075,0.0011584958,0.000029034216,0.0003205072],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00031261498,0.00061912445,0.0024137688,0.00052129506,0.00011598182,0.000025995334,0.0005451058,0.0003553778,0.007718701],"category_scores_gemma":[0.00008174494,0.0005297802,0.00087574427,0.0008309424,0.000055956436,0.00004729814,0.00030144118,0.00088711275,0.002118292],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001084904,0.0012839767,0.0000037563382,0.005200489,0.00045339507,0.002606616,0.00053652714,0.0000023785112,0.000070732116,0.0000971206,0.0011016914,0.9885348],"study_design_scores_gemma":[0.0013270554,0.00013468365,0.00011358515,0.0022351404,0.0007239833,0.00003297396,0.000019834537,0.0000036002457,0.0000046974023,0.0006977293,0.9942648,0.0004419186],"about_ca_topic_score_codex":0.000027415595,"about_ca_topic_score_gemma":0.0000027975937,"teacher_disagreement_score":0.9931631,"about_ca_system_score_codex":0.000511618,"about_ca_system_score_gemma":0.0009775116,"threshold_uncertainty_score":0.9997154},"labels":[],"label_agreement":null},{"id":"W4306893299","doi":"10.1080/15548627.2022.2138006","title":"Eructophagy: macrophages use autophagic machinery to burp out parts of their meal","year":2022,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Autophagy; Meal; Cell biology; Food science; Biochemistry; Apoptosis","score_opus":0.029197170583413555,"score_gpt":0.28834595078029807,"score_spread":0.25914878019688453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4306893299","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990962,0.0032874516,0.00018542899,0.0008360347,0.0011534769,0.0010335151,0.00037163965,0.0003567084,0.0018137029],"genre_scores_gemma":[0.98321146,0.00008993411,0.0007343821,0.004462372,0.00030647696,0.000256548,0.00013461921,0.00012280724,0.010681384],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996558,0.00025973193,0.0007903838,0.00076203246,0.00088626106,0.00074360013],"domain_scores_gemma":[0.99762505,0.0002177035,0.00026835653,0.0012106345,0.00015053598,0.0005276967],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00043636205,0.0005009317,0.00094211096,0.0004269304,0.00034951896,0.000043669694,0.000502215,0.000118356955,0.0047907634],"category_scores_gemma":[0.00010897316,0.00044523785,0.00048106117,0.0006285919,0.00015038584,0.00020322249,0.0004621962,0.0005244868,0.00018522424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008974907,0.008858019,0.023208585,0.001019575,0.00439583,0.009439741,0.023355553,0.004315863,0.67801535,0.021333653,0.063621394,0.15346156],"study_design_scores_gemma":[0.010064098,0.0042623305,0.24290577,0.00015946361,0.0006791085,0.0008879985,0.0009756355,0.0021636751,0.51355076,0.004076406,0.21860585,0.0016688806],"about_ca_topic_score_codex":0.00015601383,"about_ca_topic_score_gemma":0.000007736129,"teacher_disagreement_score":0.21969719,"about_ca_system_score_codex":0.00020015526,"about_ca_system_score_gemma":0.00032321835,"threshold_uncertainty_score":0.99979997},"labels":[],"label_agreement":null},{"id":"W4307259124","doi":"10.3410/f.742281114.793595653","title":"Faculty Opinions recommendation of Endosome maturation links PI3Kα signaling to lysosome repopulation during basal autophagy.","year":2022,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Autophagy; Lysosome; Endosome; PI3K/AKT/mTOR pathway; Basal (medicine); Cell biology; Repopulation; Biology; Signal transduction; Genetics; Biochemistry; Endocrinology; Stem cell; Apoptosis","score_opus":0.030118686524412745,"score_gpt":0.3582743586667136,"score_spread":0.32815567214230085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307259124","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00007893483,0.0009102578,0.000037192796,0.112284064,0.0012789003,0.002566341,0.88272464,0.00009011385,0.000029530185],"genre_scores_gemma":[0.00022943437,0.00023574785,0.00068450137,0.007289175,0.0006548839,0.0005644139,0.9891346,0.000057917565,0.0011493419],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9933899,0.00056338555,0.0023919495,0.0009297542,0.002273386,0.0004516063],"domain_scores_gemma":[0.99179465,0.00014118361,0.0020445797,0.0017871987,0.0037329365,0.0004994583],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0012933343,0.00065025146,0.0012923082,0.0007741836,0.00046489786,0.000118351374,0.0010209508,0.00090212084,0.0059056757],"category_scores_gemma":[0.004514666,0.00047650846,0.0009052979,0.0027659284,0.00015584395,0.00043600373,0.00050240604,0.0018591416,0.000041768762],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016879114,0.0005505292,0.00000900136,0.007827375,0.00028022082,0.0000028857287,0.00019942262,0.0000028067195,0.00012435786,0.00013023448,0.9898451,0.00085929345],"study_design_scores_gemma":[0.0013469314,0.00031127222,0.007111677,0.008078633,0.0004218552,0.00008888553,0.000043914708,0.000020459463,0.00040909092,0.000050869137,0.9817146,0.0004017967],"about_ca_topic_score_codex":0.00005301698,"about_ca_topic_score_gemma":0.0000019087172,"teacher_disagreement_score":0.106409915,"about_ca_system_score_codex":0.00037702167,"about_ca_system_score_gemma":0.0006891298,"threshold_uncertainty_score":0.9997687},"labels":[],"label_agreement":null},{"id":"W4307583163","doi":"10.1007/s00018-022-04585-8","title":"Basal Gp78-dependent mitophagy promotes mitochondrial health and limits mitochondrial ROS","year":2022,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Mitophagy; Mitochondrion; Cell biology; ATG5; Autophagy; Mitochondrial fission; Biology; Programmed cell death; Autophagosome; Mitochondrial ROS; Apoptosis; Biochemistry","score_opus":0.017490083741987194,"score_gpt":0.2753500664595366,"score_spread":0.2578599827175494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307583163","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9611784,0.031999968,0.00088152685,0.0033028813,0.0011895763,0.0008762397,0.000025025105,0.000067649875,0.00047868688],"genre_scores_gemma":[0.9907205,0.00040211083,0.001578426,0.0061548674,0.00050860696,0.00009417719,0.00003924512,0.000029280685,0.00047276897],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975282,0.00021840405,0.0003136734,0.00068995374,0.00078685815,0.00046293123],"domain_scores_gemma":[0.99886507,0.000044446006,0.00012430878,0.0002619026,0.000036669997,0.0006676242],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030028968,0.00022987291,0.0003721423,0.00016692124,0.00085284887,0.00007829495,0.00020427509,0.000060471626,0.00015859892],"category_scores_gemma":[0.00011266048,0.00020200545,0.00011424227,0.00029794918,0.0004050815,0.00010036619,0.00017362736,0.0002509845,0.0000054750103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007953858,0.0007134507,0.0019684276,0.00020099591,0.00020567814,0.00072002754,0.0024266192,0.000044321812,0.9802108,0.0022374343,0.0042522694,0.006224579],"study_design_scores_gemma":[0.02114559,0.016265385,0.0025727188,0.0002546276,0.00043415205,0.0007879072,0.0072085094,0.004086489,0.87806267,0.008381463,0.058687937,0.0021125441],"about_ca_topic_score_codex":0.000057269084,"about_ca_topic_score_gemma":0.0000022702332,"teacher_disagreement_score":0.10214813,"about_ca_system_score_codex":0.000035841615,"about_ca_system_score_gemma":0.0007448552,"threshold_uncertainty_score":0.8237543},"labels":[],"label_agreement":null},{"id":"W4307656792","doi":"10.1038/s41467-022-33946-x","title":"Multi-omics characterization of autophagy-related molecular features for therapeutic targeting of autophagy","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SKiN Health","funders":"National Key Research and Development Program of China; China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"Autophagy; Cancer cell; Cancer research; Drug resistance; Cancer; Biology; Medicine; Computational biology; Bioinformatics; Cell biology; Apoptosis; Biochemistry; Genetics","score_opus":0.016962536821698453,"score_gpt":0.31835805618530927,"score_spread":0.3013955193636108,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307656792","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9523892,0.038763456,0.0020380318,0.0033611374,0.00037315776,0.0019461296,0.0006108717,0.0001615133,0.00035654585],"genre_scores_gemma":[0.9882553,0.0004949477,0.008065946,0.0007782689,0.000015905336,0.00018200594,0.0019169268,0.000039175837,0.00025148157],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988813,0.00016530906,0.0004179183,0.00016904814,0.00021716653,0.0001493008],"domain_scores_gemma":[0.99807787,0.00015262724,0.00036703862,0.0010967224,0.00025517028,0.000050589064],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027237015,0.0001342972,0.0003072137,0.0001555689,0.00025157357,0.0000055095793,0.00056334253,0.0001870366,0.00007664799],"category_scores_gemma":[0.00009266544,0.0001343009,0.00021107052,0.00039864978,0.00011324707,0.0000508976,0.000184136,0.00066500105,8.17885e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001431127,0.0007559936,0.0004525416,0.00006508766,0.00031747145,0.0000016067814,0.00072827155,0.00006429383,0.9801132,0.015277705,0.00010658591,0.0019741312],"study_design_scores_gemma":[0.006474107,0.00060973305,0.16110687,0.00009947224,0.00081543246,0.00003692339,0.00055759796,0.024889342,0.7767242,0.0017056905,0.026538886,0.00044175374],"about_ca_topic_score_codex":0.00000605133,"about_ca_topic_score_gemma":0.0000010796728,"teacher_disagreement_score":0.203389,"about_ca_system_score_codex":0.00006350264,"about_ca_system_score_gemma":0.00015998636,"threshold_uncertainty_score":0.5476632},"labels":[],"label_agreement":null},{"id":"W4307847576","doi":"10.1139/cjpp-2022-0341","title":"Activation of the Akt/FoxO3 signaling pathway enhances oxidative stress-induced autophagy and alleviates brain damage in a rat model of ischemic stroke","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autophagy; FOXO3; Protein kinase B; Oxidative stress; PI3K/AKT/mTOR pathway; LY294002; Cell biology; Signal transduction; Reactive oxygen species; FOXO1; Programmed cell death; Apoptosis; Neuroprotection; Chemistry; Biology; Pharmacology; Endocrinology; Biochemistry","score_opus":0.018938062933469644,"score_gpt":0.27910941442453585,"score_spread":0.2601713514910662,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307847576","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99814075,0.00074971194,0.000007540265,0.0007028018,0.0001370478,0.00014552462,0.00006352537,0.0000011981953,0.00005190276],"genre_scores_gemma":[0.9989515,0.00004493655,0.000022747316,0.0008563194,0.0000524234,0.000007755186,0.0000058915944,0.0000065672343,0.000051867693],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913996,0.00024932477,0.0002825543,0.00010781636,0.00006648372,0.00015386181],"domain_scores_gemma":[0.9992345,0.0001893242,0.00032584684,0.000060537594,0.0000681026,0.00012171054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021412395,0.00009129541,0.00031883514,0.00016348355,0.000097501616,0.000001459876,0.000110793124,0.000059892456,0.00043926854],"category_scores_gemma":[0.000031705116,0.00007142311,0.00005616247,0.00010209817,0.00019753574,0.00006532773,0.00002700217,0.00036244316,5.964281e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037432887,0.00005710141,0.0010681321,0.00006228613,0.00014006431,0.00001569452,0.0017277936,0.0013607016,0.99457496,0.00007432858,0.00026761089,0.00027701873],"study_design_scores_gemma":[0.0016292746,0.00042401053,0.003331809,0.00003535858,0.000055554196,0.000014896786,0.0005521449,0.0012336717,0.99201316,0.000567386,0.00008936934,0.000053392567],"about_ca_topic_score_codex":0.00019036113,"about_ca_topic_score_gemma":0.00013544297,"teacher_disagreement_score":0.0025618076,"about_ca_system_score_codex":0.000042808035,"about_ca_system_score_gemma":0.00081805495,"threshold_uncertainty_score":0.48096824},"labels":[],"label_agreement":null},{"id":"W4308327090","doi":"10.1016/j.cophys.2022.100614","title":"Recent insights concerning autophagy and endothelial cell nitric oxide generation","year":2022,"lang":"en","type":"article","venue":"Current Opinion in Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Heart, Lung, and Blood Institute; University of Utah; Alzheimer's Association; American Heart Association; National Institute on Aging; National Institutes of Health","keywords":"Autophagy; Nitric oxide; Context (archaeology); Endothelial dysfunction; Coronary artery disease; Endothelial stem cell; Endothelium; Disease; Homeostasis; Medicine; Biology; Cell biology; Internal medicine; Biochemistry; Apoptosis","score_opus":0.06209085719084996,"score_gpt":0.328232482143447,"score_spread":0.2661416249525971,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308327090","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96828914,0.028836308,0.000026053947,0.00007825665,0.0022972028,0.0002853141,0.000015468531,0.000035577432,0.00013667006],"genre_scores_gemma":[0.9859285,0.012640345,0.000028697805,0.00020933115,0.0006832638,0.00013887224,0.00030875718,0.000014556835,0.00004769959],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989735,0.00018210142,0.00023067287,0.00029954285,0.00013321736,0.00018096346],"domain_scores_gemma":[0.99960965,0.00004327677,0.000091470174,0.0001550848,0.000028506762,0.000071992625],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007091935,0.000121482786,0.00022178376,0.00014498342,0.0001327741,0.000005185799,0.00006447746,0.00003891767,0.00038113943],"category_scores_gemma":[0.000015340305,0.000115096715,0.00004120547,0.00018168162,0.00005254053,0.000042238804,0.00008984178,0.0002788399,0.000013225354],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071615406,0.0012384977,0.0021993692,0.00022954155,0.00005010471,0.0000114121785,0.0011912019,0.0009678291,0.89793855,0.0030533816,0.0059220847,0.08648185],"study_design_scores_gemma":[0.01004821,0.00083011156,0.14349256,0.00008054368,0.00004278456,0.00004693736,0.00034054043,0.015342518,0.034286864,0.0027839672,0.79220784,0.0004971447],"about_ca_topic_score_codex":0.0000068901995,"about_ca_topic_score_gemma":1.6287304e-7,"teacher_disagreement_score":0.8636517,"about_ca_system_score_codex":0.00009450713,"about_ca_system_score_gemma":0.00010838081,"threshold_uncertainty_score":0.46935076},"labels":[],"label_agreement":null},{"id":"W4308345286","doi":"10.1016/j.cophys.2022.100613","title":"Mechanisms and physiological functions of ER-phagy","year":2022,"lang":"en","type":"article","venue":"Current Opinion in Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Innovative Medicines Initiative; Innovative Health Initiative; Kungliga Tekniska Högskolan; Deutsche Forschungsgemeinschaft; Dr. Rolf M. Schwiete Stiftung; European Federation of Pharmaceutical Industries and Associations; McGill University","keywords":"Endoplasmic reticulum; Cell biology; Autophagy; Homeostasis; Organelle; Receptor; Biology; Process (computing); Chemistry; Biochemistry; Computer science; Apoptosis","score_opus":0.0713964648703913,"score_gpt":0.3547643499649796,"score_spread":0.28336788509458827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308345286","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992911,0.0037945493,0.00018454395,0.00016420062,0.0025165929,0.00026135263,0.000044906363,0.00003194847,0.00009095247],"genre_scores_gemma":[0.99888563,0.0005448383,0.000045102137,0.00009217504,0.00011523668,0.0001186789,0.00016238204,0.000007415283,0.000028537479],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992157,0.000110260924,0.00019703631,0.00023022658,0.00009787245,0.00014888532],"domain_scores_gemma":[0.99964887,0.00004179393,0.00007042392,0.00016536599,0.000020996664,0.00005253868],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000071905226,0.00009153488,0.00026150263,0.00009492921,0.00006923883,0.0000010116244,0.000063516156,0.000035241548,0.00080862833],"category_scores_gemma":[0.000015646434,0.00007877404,0.000066826564,0.00016057039,0.00009403035,0.00002105686,0.00012197938,0.0002197838,0.000007687157],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020592657,0.004535877,0.0025446718,0.00073703035,0.00018193193,0.000004940447,0.0006648296,0.0004953615,0.8654561,0.07762505,0.0151563315,0.030538613],"study_design_scores_gemma":[0.00546474,0.0032442647,0.88294727,0.00011261635,0.00004703179,0.000046527075,0.00072112615,0.0015463773,0.0023168777,0.07029833,0.032928698,0.00032612373],"about_ca_topic_score_codex":0.00000425286,"about_ca_topic_score_gemma":6.598523e-8,"teacher_disagreement_score":0.8804026,"about_ca_system_score_codex":0.000025225707,"about_ca_system_score_gemma":0.00004446539,"threshold_uncertainty_score":0.88539135},"labels":[],"label_agreement":null},{"id":"W4308592517","doi":"10.1007/978-3-031-17362-2_6","title":"Autophagy in Muscle Stem Cells","year":2022,"lang":"en","type":"book-chapter","venue":"Stem cell biology and regenerative medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Myogenesis; Cell biology; Autophagy; Myocyte; Skeletal muscle; Stem cell; Biology; Progenitor cell; Cellular differentiation; Regeneration (biology); Anatomy; Biochemistry; Apoptosis","score_opus":0.023813068152128258,"score_gpt":0.26915395846924206,"score_spread":0.2453408903171138,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308592517","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.062487256,0.1822304,0.000040496365,0.001973472,0.002269057,0.0018287128,0.00021879406,0.0001366013,0.74881524],"genre_scores_gemma":[0.1589315,0.01476911,0.00003055791,0.0018887763,0.0009691277,0.000074779135,0.00036353397,0.00009069117,0.82288194],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979124,0.00015162867,0.00059340976,0.0007834608,0.0002078806,0.00035120975],"domain_scores_gemma":[0.9988244,0.00016071551,0.00027546025,0.0004405783,0.00006659879,0.00023225237],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003454573,0.0005357517,0.001212397,0.00035322932,0.00016336898,0.0000035971934,0.00014079023,0.00054570736,0.004994064],"category_scores_gemma":[0.0000019393128,0.0003781307,0.00013420523,0.000073873096,0.0007098747,0.000028283475,0.000114395094,0.000855243,0.0000457841],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022127118,0.0006832355,0.0006681877,0.0018401752,0.0018518657,0.0063307593,0.00871589,0.000029320066,0.2898435,0.43395874,0.025250282,0.22861534],"study_design_scores_gemma":[0.0061258245,0.0035404807,0.00027561796,0.000513649,0.00044185965,0.000069940405,0.00051557703,0.000059193342,0.03585726,0.0028395895,0.949077,0.000683973],"about_ca_topic_score_codex":0.00002785347,"about_ca_topic_score_gemma":0.000013546041,"teacher_disagreement_score":0.92382675,"about_ca_system_score_codex":0.00012572629,"about_ca_system_score_gemma":0.00018050152,"threshold_uncertainty_score":0.9998671},"labels":[],"label_agreement":null},{"id":"W4310171762","doi":"10.3390/cancers14235839","title":"New Visions on Natural Products and Cancer Therapy: Autophagy and Related Regulatory Pathways","year":2022,"lang":"en","type":"review","venue":"Cancers","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research Institute in Oncology and Hematology; University of Manitoba; CancerCare Manitoba; University of Toronto","funders":"National Institute of General Medical Sciences; Instituto de Salud Carlos III; Iran National Science Foundation","keywords":"Autophagy; Cell biology; Biology; Programmed cell death; Cancer; Kinase; Apoptosis; Cancer research; Biochemistry; Genetics","score_opus":0.04588005866861705,"score_gpt":0.3321459167043216,"score_spread":0.28626585803570453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310171762","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018182049,0.99460995,9.857184e-8,0.00013089937,0.0012580014,0.001176747,0.00006037272,0.00011573656,0.00082998106],"genre_scores_gemma":[0.00041782847,0.99167186,0.00002122788,0.0005751949,0.0004229945,0.00021449658,0.0001147055,0.00009913789,0.0064625605],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982955,0.00008207729,0.00033901865,0.0006958336,0.00029831103,0.00028927877],"domain_scores_gemma":[0.9988948,0.00007669132,0.00022197657,0.00051894767,0.000027983371,0.0002596144],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000116057316,0.00043253077,0.0011258272,0.00017365193,0.00018034328,0.00002093607,0.00012014393,0.00020449651,0.0011796533],"category_scores_gemma":[0.000031775773,0.00032304178,0.00019244922,0.00036424067,0.00011176393,0.000052363324,0.000056041932,0.0007303119,0.000007540978],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000081329614,0.00001172278,0.0000015692807,0.0017386446,0.00050205446,0.00009963107,0.00021954831,0.0000011668897,0.000011551603,0.00027036024,0.007264668,0.9897978],"study_design_scores_gemma":[0.001072306,0.00023730475,0.00016499999,0.0038031111,0.00053929334,0.00008571492,0.000021733156,0.000008064684,0.00003099693,0.000086235756,0.9936357,0.00031451476],"about_ca_topic_score_codex":0.00011238398,"about_ca_topic_score_gemma":0.0000020737248,"teacher_disagreement_score":0.98948324,"about_ca_system_score_codex":0.0011238862,"about_ca_system_score_gemma":0.0041466192,"threshold_uncertainty_score":0.99992216},"labels":[],"label_agreement":null},{"id":"W4311649106","doi":"10.21203/rs.3.rs-2277978/v1","title":"Alterations of Lipid-Mediated Mitophagy Result in Aging-Dependent Sensorimotor Defects","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; York University; University of South Carolina; Northwestern University; Medical University of South Carolina; U.S. Department of Veterans Affairs","keywords":"Mitophagy; Neuroscience; Psychology; Cell biology; Chemistry; Autophagy; Biology; Biochemistry","score_opus":0.05720653202765194,"score_gpt":0.41706398631808994,"score_spread":0.35985745429043803,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311649106","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987024,0.0042234357,0.000016438296,0.00089064287,0.00047472634,0.0025397318,0.0006814855,0.00009656012,0.004052962],"genre_scores_gemma":[0.99323475,0.0016030794,0.00011349329,0.000109944005,0.00063677406,0.0006885385,0.0012029619,0.00007510754,0.0023353572],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9948354,0.001040825,0.0006829477,0.0007632402,0.0019907278,0.00068687985],"domain_scores_gemma":[0.9968842,0.000775116,0.00016996884,0.0012362837,0.00059231796,0.00034206372],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0016098052,0.00029131447,0.0006804653,0.0012361187,0.0001651203,0.000045108463,0.00040508126,0.000318948,0.0022607064],"category_scores_gemma":[0.0011843467,0.00028609633,0.00029316635,0.000793385,0.00016787372,0.000052376745,0.0008598754,0.0026494341,0.000079774465],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015922489,0.024609692,0.5704573,0.04487661,0.0043655843,0.02345268,0.031167835,0.015300228,0.19317241,0.005167962,0.06049318,0.011014031],"study_design_scores_gemma":[0.022498911,0.0050099273,0.7925829,0.008868137,0.00027737528,0.00008775507,0.0065509956,0.006222768,0.10990964,0.0054282094,0.040506784,0.0020565875],"about_ca_topic_score_codex":0.0006228392,"about_ca_topic_score_gemma":0.000073625604,"teacher_disagreement_score":0.2221256,"about_ca_system_score_codex":0.0006300962,"about_ca_system_score_gemma":0.0016011895,"threshold_uncertainty_score":0.9999591},"labels":[],"label_agreement":null},{"id":"W4311762450","doi":"10.1016/j.jmccpl.2022.100027","title":"MicroRNA miR-378-3p is a novel regulator of endothelial autophagy and function","year":2022,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology Plus","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Western University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Cell biology; microRNA; Endothelial stem cell; Regulator; Nitric Oxide Synthase Type III; BAG3; Chemistry; Downregulation and upregulation; Antagomir; Biology; Enos; Apoptosis; Nitric oxide synthase; Biochemistry; Nitric oxide; Endocrinology","score_opus":0.008730542343862498,"score_gpt":0.22275103222392745,"score_spread":0.21402048988006495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311762450","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9726569,0.020734552,0.005668625,0.00025275222,0.0003231436,0.0001373426,0.000037596983,0.000006355843,0.0001827036],"genre_scores_gemma":[0.99832433,0.00020831673,0.00025365604,0.0008334152,0.00017968968,0.0000044287576,0.000008200034,0.000019384139,0.000168562],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891484,0.000121209596,0.00037310112,0.00017210805,0.00025714777,0.00016159528],"domain_scores_gemma":[0.999292,0.000026664968,0.00026885024,0.00017717962,0.00009782437,0.00013746961],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035127407,0.00013729738,0.0005746174,0.00014826718,0.00008755425,0.0000055520823,0.00007309438,0.00009279285,0.00008486514],"category_scores_gemma":[0.000019637402,0.00012050775,0.00030502447,0.0000875008,0.00013217599,0.00003242225,0.00006972525,0.00029547975,6.9164327e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014672665,0.000065777574,0.00068976235,0.000046596288,0.0008811664,0.0008584277,0.00024193087,0.00007236166,0.9939714,0.00026235468,0.00040209666,0.0010408589],"study_design_scores_gemma":[0.016797537,0.004638675,0.014969965,0.00006741025,0.0022669146,0.01393386,0.0008317434,0.00034417555,0.89540285,0.0012382157,0.04915382,0.00035484106],"about_ca_topic_score_codex":0.0000054434386,"about_ca_topic_score_gemma":5.044585e-8,"teacher_disagreement_score":0.09856856,"about_ca_system_score_codex":0.000045636527,"about_ca_system_score_gemma":0.00017388944,"threshold_uncertainty_score":0.49141634},"labels":[],"label_agreement":null},{"id":"W4312193610","doi":"10.1016/j.apsb.2022.12.015","title":"Author correction to ‘Ablation of Akt2 and AMPKα2 rescues high fat diet-induced obesity and hepatic steatosis through Parkin-mediated mitophagy’ [Acta Pharmaceutica Sinica B 11 (2021) 3508–3526]","year":2022,"lang":"en","type":"erratum","venue":"Acta Pharmaceutica Sinica B","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Steatosis; Mitophagy; AMPK; Parkin; Chemistry; Endocrinology; Internal medicine; Medicine; Autophagy; Biochemistry; Apoptosis; Kinase; Protein kinase A","score_opus":0.047201891567319444,"score_gpt":0.3570940204941811,"score_spread":0.30989212892686163,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312193610","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93373334,0.01027195,0.000021129285,0.012520509,0.031561196,0.0049622715,0.0010193803,0.000511026,0.005399164],"genre_scores_gemma":[0.959881,0.014614749,0.00027282423,0.0030461664,0.0018610646,0.00033770764,0.0017943124,0.00027757225,0.01791462],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99227273,0.0010949367,0.001886868,0.0019943165,0.0015758998,0.0011752298],"domain_scores_gemma":[0.9937653,0.0020102717,0.0010984387,0.0014788315,0.00043166577,0.0012155247],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001016218,0.0012806084,0.0023992583,0.0005784178,0.00068037224,0.00013946937,0.0006040127,0.00092266937,0.0050489283],"category_scores_gemma":[0.0012708225,0.001273396,0.0004840578,0.0011790358,0.0004739206,0.00046602334,0.00074356067,0.0026984548,0.000056112516],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009876207,0.0031519851,0.0064193816,0.0020850836,0.003895073,0.00027456248,0.002556887,0.000003909343,0.06463548,0.000056908604,0.89453506,0.012509488],"study_design_scores_gemma":[0.007555412,0.0024646479,0.028950902,0.0012008722,0.006023062,0.000087266686,0.00050381746,0.0024447287,0.029775538,0.00013284745,0.9192216,0.0016393025],"about_ca_topic_score_codex":0.0005510579,"about_ca_topic_score_gemma":0.000064083426,"teacher_disagreement_score":0.03485994,"about_ca_system_score_codex":0.00050391536,"about_ca_system_score_gemma":0.0008317208,"threshold_uncertainty_score":0.9999946},"labels":[],"label_agreement":null},{"id":"W4312562391","doi":"10.1161/atvb.42.suppl_1.207","title":"Abstract 207: Autophagy Is Differentially Regulated In Leukocyte And Nonleukocyte Foam Cells During Atherosclerosis","year":2022,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute; University of Ottawa; Ottawa Heart Institute","funders":"","keywords":"Autophagy; Foam cell; Bafilomycin; Lipid droplet; Cell biology; Ex vivo; Cholesterol; Chemistry; In vivo; Efflux; Biology; In vitro; Lipoprotein; Biochemistry; Apoptosis","score_opus":0.022605819011065096,"score_gpt":0.2660919281987423,"score_spread":0.24348610918767719,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312562391","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981395,0.0005545169,0.0000137589295,0.00034846266,0.00021090884,0.00051463954,0.000059882997,0.00009081137,0.00006754726],"genre_scores_gemma":[0.9919295,0.0065566073,0.00010734457,0.0010447607,0.000071326525,0.00014324735,0.00005680724,0.000060883,0.000029577672],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9976692,0.00016957396,0.0005357283,0.00082088425,0.00022729454,0.0005773147],"domain_scores_gemma":[0.9989963,0.000048769874,0.00016098442,0.00052373455,0.000035232315,0.00023495241],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002760579,0.0003934263,0.0007998718,0.00023770833,0.000435217,0.00005135599,0.0001676237,0.00019549982,0.001123268],"category_scores_gemma":[0.0000072857615,0.0003696114,0.00025397117,0.00026162883,0.00023553612,0.0001056164,0.00030745924,0.00035985647,0.000013069114],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051692754,0.00041476704,0.071717575,0.00008484449,0.00040953164,0.0000013618802,0.00087060116,0.0000046842215,0.92570746,0.00007277146,0.000068138695,0.0005965817],"study_design_scores_gemma":[0.004421148,0.00045671535,0.9590925,0.00008639937,0.00015535072,0.0000035362684,0.0001765916,0.00020165736,0.034302562,0.00008034811,0.0006670616,0.0003561037],"about_ca_topic_score_codex":0.00020206539,"about_ca_topic_score_gemma":0.000022994485,"teacher_disagreement_score":0.89140487,"about_ca_system_score_codex":0.0001205585,"about_ca_system_score_gemma":0.00005792406,"threshold_uncertainty_score":0.9998756},"labels":[],"label_agreement":null},{"id":"W4312800401","doi":"10.1161/atvb.42.suppl_1.102","title":"Abstract 102: Autophagy Is Differentially Regulated In Leukocyte And Nonleukocyte Foam Cells During Atherosclerosis","year":2022,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute; University of Ottawa; Ottawa Heart Institute","funders":"","keywords":"Autophagy; Foam cell; Bafilomycin; Lipid droplet; Cell biology; Ex vivo; Cholesterol; Vascular smooth muscle; Efflux; In vivo; Chemistry; Biology; Lipoprotein; In vitro; Endocrinology; Biochemistry; Apoptosis","score_opus":0.022918502104392193,"score_gpt":0.2657945046611835,"score_spread":0.2428760025567913,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312800401","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99819285,0.00051519566,0.000014118522,0.00034353047,0.00020133331,0.0005139855,0.000058065714,0.00009391687,0.00006698652],"genre_scores_gemma":[0.9923576,0.006134447,0.00010705697,0.0010419113,0.00006895031,0.0001434591,0.000056241664,0.00006148341,0.000028817622],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99766356,0.00017206422,0.0005366958,0.0008231072,0.0002280305,0.0005765231],"domain_scores_gemma":[0.9989941,0.00004983589,0.00016110283,0.00052535604,0.000035167228,0.00023442459],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00027563894,0.00039435911,0.000802342,0.00023907369,0.00043791486,0.000051915817,0.00016826387,0.00019564318,0.0011060798],"category_scores_gemma":[0.000007536227,0.00037044522,0.00025587075,0.0002634941,0.00023672995,0.00010736377,0.0003094318,0.0003570983,0.00001283125],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005172551,0.000411316,0.06908059,0.000085333166,0.00040618356,0.000001353089,0.0009091291,0.0000044281396,0.9282793,0.00007468561,0.00005519244,0.0006407642],"study_design_scores_gemma":[0.004419876,0.0004608661,0.95579344,0.00008710265,0.00015519086,0.0000035692776,0.00017909831,0.00019347602,0.037642837,0.00008206636,0.00062675227,0.00035575428],"about_ca_topic_score_codex":0.00019167196,"about_ca_topic_score_gemma":0.000022555036,"teacher_disagreement_score":0.89063644,"about_ca_system_score_codex":0.00012168023,"about_ca_system_score_gemma":0.000057333717,"threshold_uncertainty_score":0.9998748},"labels":[],"label_agreement":null},{"id":"W4313237462","doi":"10.1007/s12035-022-03170-1","title":"Autophagic Molecular Alterations in the Mouse Cerebellum Experimental Autoimmune Encephalomyelitis Model Following Treatment with Cannabidiol and Fluoxetine","year":2022,"lang":"en","type":"article","venue":"Molecular Neurobiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"","keywords":"Experimental autoimmune encephalomyelitis; Luxol fast blue stain; Autophagy; Apoptosis; Multiple sclerosis; Oligodendrocyte; Cerebellum; Myelin; Immunology; Biology; Medicine; Neuroscience; Central nervous system; Biochemistry","score_opus":0.009928183695389517,"score_gpt":0.2557137264659782,"score_spread":0.24578554277058867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313237462","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946897,0.0024097813,0.000314211,0.0013788131,0.000051067567,0.0007855481,0.000026267455,0.00005072737,0.00029386833],"genre_scores_gemma":[0.9950643,0.000029079387,0.00021894941,0.0035542473,0.0000135411965,0.00058823905,0.00016061479,0.000036582176,0.00033440208],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985502,0.00031944644,0.0002235699,0.00042508222,0.00015790225,0.00032380305],"domain_scores_gemma":[0.99941707,0.000023399793,0.000052586267,0.00042158246,0.000013873806,0.000071498864],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009532924,0.00023456087,0.00030276374,0.000110094006,0.00021912462,0.000017708922,0.00014070846,0.000045113527,0.00007293011],"category_scores_gemma":[0.000006510697,0.00017064906,0.000121224104,0.0001858523,0.00009582433,0.000033674274,0.00007696116,0.00020820744,0.0000024938065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022824304,0.000519654,0.0002847506,0.0000056682943,0.0001261083,0.0029675642,0.0018530173,0.0047394047,0.988247,0.0007302396,0.00003525832,0.0002630854],"study_design_scores_gemma":[0.030243995,0.022383597,0.014538175,0.000055880897,0.0007126838,0.0047022738,0.0045680604,0.061579425,0.8513814,0.0007961739,0.0073628468,0.0016754429],"about_ca_topic_score_codex":0.00014201584,"about_ca_topic_score_gemma":0.00000548877,"teacher_disagreement_score":0.13686556,"about_ca_system_score_codex":0.000105912644,"about_ca_system_score_gemma":0.00013297166,"threshold_uncertainty_score":0.6958867},"labels":[],"label_agreement":null},{"id":"W4313358971","doi":"10.4049/jimmunol.202.supp.177.27","title":"Parkinson’s disease related proteins PINK1 and Parkin are major regulators of the immune system","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Parkin; PINK1; Substantia nigra; Dopaminergic; Parkinson's disease; Immunology; Mitophagy; Immune system; Biology; Inflammation; Neuroscience; Mitochondrion; T cell; Cell biology; Disease; Dopamine; Medicine; Internal medicine; Autophagy; Apoptosis","score_opus":0.004961479046235228,"score_gpt":0.21134815684170746,"score_spread":0.20638667779547223,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313358971","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9580887,0.038695484,0.0000055573255,0.002122315,0.0004212786,0.0005028244,0.000005134446,0.000012220474,0.00014651286],"genre_scores_gemma":[0.9986845,0.00056835584,0.000016279073,0.00008492633,0.000051027262,0.0000039233346,7.5334026e-7,0.000019496218,0.00057073135],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99861276,0.00034415876,0.0005626464,0.000088170724,0.00021719983,0.00017506702],"domain_scores_gemma":[0.9982407,0.000089034445,0.0008966051,0.00056484266,0.00013938433,0.0000694118],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054666435,0.00013337137,0.00044640782,0.00008111917,0.00008310379,0.000004975863,0.0002888316,0.000097968375,0.000082618106],"category_scores_gemma":[0.000072758914,0.00006472759,0.0001849902,0.00015327294,0.00026012195,0.00005506228,0.00007936041,0.00038484702,0.00001285283],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.034248263,0.0014046475,0.32752103,0.0017449914,0.010886243,0.0005431764,0.005727374,0.00011810251,0.59542865,0.01364668,0.0007187169,0.008012101],"study_design_scores_gemma":[0.0033640892,0.00047716318,0.96583194,0.001057827,0.0005822721,0.0008944166,0.0011271355,0.00004535099,0.02442348,0.0005273468,0.0015844759,0.00008451109],"about_ca_topic_score_codex":0.000017275994,"about_ca_topic_score_gemma":6.5459756e-7,"teacher_disagreement_score":0.6383109,"about_ca_system_score_codex":0.00006200667,"about_ca_system_score_gemma":0.00015852936,"threshold_uncertainty_score":0.26395142},"labels":[],"label_agreement":null},{"id":"W4313383897","doi":"10.4049/jimmunol.200.supp.170.19","title":"mTOR induces lysosome expansion by selective translation of lysosomal transcripts during phagocyte activation","year":2018,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Toronto Metropolitan University","funders":"","keywords":"Lysosome; Cell biology; TFEB; Autophagy; Biology; PI3K/AKT/mTOR pathway; Endocytosis; ATG16L1; Endosome; Signal transduction; Biochemistry; Cell; Intracellular; Apoptosis","score_opus":0.017126310302656447,"score_gpt":0.2725901730473346,"score_spread":0.2554638627446782,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313383897","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995241,0.0029802872,0.0005218097,0.00068640173,0.00020098397,0.00014818733,0.000002968593,0.000011135124,0.00020724437],"genre_scores_gemma":[0.9989692,0.0005181305,0.000084575084,0.00011180024,0.00023525654,0.000001552372,0.0000031641193,0.000014553851,0.0000617991],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989991,0.00016365702,0.00041224362,0.00007377084,0.00019878602,0.00015240427],"domain_scores_gemma":[0.9990812,0.00007596611,0.00039208628,0.00014032656,0.0002738026,0.000036607067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023693187,0.00010929083,0.00029162166,0.00014561701,0.0001002778,0.0000033544218,0.00013247166,0.000112002264,0.00009468483],"category_scores_gemma":[0.00003043563,0.000071339484,0.0001304521,0.0001885909,0.00021729503,0.00021321385,0.000006266259,0.00025905255,0.00000400567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0055877315,0.00016962427,0.00011318237,0.000014898984,0.0005082815,0.0000033306826,0.0037330682,0.0000023822454,0.98226583,0.000021153834,0.000034989913,0.007545512],"study_design_scores_gemma":[0.0030697966,0.001719681,0.044333063,0.000101151665,0.00020607923,0.00021204179,0.00047318736,0.000008434215,0.94941205,0.0002463557,0.00015986583,0.00005826947],"about_ca_topic_score_codex":0.0000111544605,"about_ca_topic_score_gemma":8.137541e-7,"teacher_disagreement_score":0.04421988,"about_ca_system_score_codex":0.00005636506,"about_ca_system_score_gemma":0.00013625,"threshold_uncertainty_score":0.29091397},"labels":[],"label_agreement":null},{"id":"W4313405858","doi":"10.4049/jimmunol.208.supp.115.04","title":"Intestinal epithelial autophagy protects from cytokine-driven mortality and IFNγ-dependent cell death in acute small intestinal injury","year":2022,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; University of Toronto","funders":"","keywords":"ATG16L1; Autophagy; Programmed cell death; Necroptosis; Intestinal epithelium; Biology; Intestinal mucosa; Apoptosis; Proinflammatory cytokine; Cytokine; Immunology; Inflammation; Cancer research; Cell biology; Epithelium; Medicine; Internal medicine","score_opus":0.024420703781624403,"score_gpt":0.28264819967225235,"score_spread":0.25822749589062793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313405858","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962943,0.0020034723,0.00036041395,0.0005202022,0.0003093928,0.00035139098,0.000042273572,0.000020952612,0.00009756759],"genre_scores_gemma":[0.99819124,0.00036954778,0.000687878,0.00043566458,0.00016642868,0.000021659262,0.0000073576593,0.000024515057,0.00009569707],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99809617,0.0005481637,0.00060270354,0.00017449829,0.0002824047,0.00029604184],"domain_scores_gemma":[0.99875134,0.00023563932,0.0004986572,0.0003165845,0.00010567297,0.00009210865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007041229,0.00020253175,0.00048687198,0.00020083562,0.00015046902,0.000011546229,0.00040465017,0.00007097451,0.0003112449],"category_scores_gemma":[0.00011746689,0.00014319399,0.00010897066,0.00015700176,0.00017633836,0.000066326735,0.0003164829,0.0013388311,0.0000064427495],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011744207,0.0009817024,0.042248536,0.000027095175,0.00090723636,0.003186184,0.0020885395,0.00012655956,0.9337887,0.00014790395,0.00006541144,0.004687899],"study_design_scores_gemma":[0.009444468,0.008759941,0.7176688,0.00019657375,0.00092946854,0.0113131115,0.0010437014,0.0006843971,0.2425402,0.0066606374,0.0004119142,0.00034682776],"about_ca_topic_score_codex":0.000491987,"about_ca_topic_score_gemma":0.000020276102,"teacher_disagreement_score":0.69124854,"about_ca_system_score_codex":0.00018930517,"about_ca_system_score_gemma":0.00035863745,"threshold_uncertainty_score":0.5839281},"labels":[],"label_agreement":null},{"id":"W4313423959","doi":"10.1080/15548627.2022.2160566","title":"PEX13 prevents pexophagy by regulating ubiquitinated PEX5 and peroxisomal ROS","year":2022,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Research Foundation of Korea; Canadian Institutes of Health Research; Hospital for Sick Children; National Research Foundation","keywords":"Peroxisome; Biology; Cell biology; Autophagy; ATG5; Biochemistry","score_opus":0.008106210991931354,"score_gpt":0.25611516662125067,"score_spread":0.24800895562931932,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313423959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913264,0.0050543565,0.00004058834,0.00034991145,0.00020728608,0.0005178453,0.00007094196,0.0002472554,0.0021854313],"genre_scores_gemma":[0.9866598,0.00007740764,0.00021306405,0.0015938333,0.00014157139,0.00015499874,0.00017934041,0.00006674179,0.010913219],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980104,0.00015120841,0.0003599123,0.0005054747,0.0005112261,0.0004617987],"domain_scores_gemma":[0.99909014,0.00006760999,0.00014554299,0.0003937905,0.00004566796,0.00025728173],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00025377196,0.00025731607,0.0003808507,0.00011310119,0.0004965463,0.000032365042,0.00016498478,0.000078624325,0.002896974],"category_scores_gemma":[0.000046767924,0.00026235133,0.0001254995,0.00026644193,0.000096014395,0.00012479318,0.00023541365,0.0003554785,0.000026617485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026345926,0.004098722,0.018264325,0.00060255785,0.0014011306,0.0021489721,0.008787974,0.00011893611,0.7907426,0.0065921997,0.052381843,0.11222618],"study_design_scores_gemma":[0.028256541,0.0059235855,0.22872226,0.00024229356,0.000746271,0.0030646233,0.004129878,0.013960677,0.5767011,0.0045700422,0.1313835,0.0022992452],"about_ca_topic_score_codex":0.000048980186,"about_ca_topic_score_gemma":6.3880714e-7,"teacher_disagreement_score":0.21404147,"about_ca_system_score_codex":0.00012111465,"about_ca_system_score_gemma":0.000118857184,"threshold_uncertainty_score":0.9999829},"labels":[],"label_agreement":null},{"id":"W4313424085","doi":"10.1016/j.lfs.2022.121335","title":"Combined effects of high fat diet and exercise on autophagy in white adipose tissue of mice","year":2022,"lang":"en","type":"article","venue":"Life Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Tehran University of Medical Sciences and Health Services","keywords":"White adipose tissue; Adipose tissue; Autophagy; White (mutation); Internal medicine; Endocrinology; Medicine; Biology; Biochemistry; Gene","score_opus":0.00906368990576932,"score_gpt":0.26796584021267,"score_spread":0.25890215030690067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313424085","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960959,0.0025256001,0.0000019468919,0.00039106735,0.00019113887,0.00030196083,0.000008672155,0.000013003256,0.0004707001],"genre_scores_gemma":[0.9990059,0.00011295748,0.00010310821,0.00037587955,0.000017704964,0.000025609277,0.0000029441392,0.0000046769687,0.0003511762],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991011,0.00005833277,0.00017548203,0.0001935989,0.00033657035,0.00013492737],"domain_scores_gemma":[0.99955654,0.00012456426,0.0000865105,0.00013340777,0.000015746005,0.00008320648],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020977865,0.00007716088,0.00026779165,0.00015435107,0.00007385139,0.0000035239634,0.00013512264,0.000021178499,0.00017724084],"category_scores_gemma":[0.000059936858,0.00006240877,0.000026295975,0.00042934984,0.00024648008,0.000049593727,0.00006247661,0.00007615777,0.0000025522868],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.019751212,0.011613125,0.37214607,0.0050177146,0.0004072006,0.0010892405,0.030834656,0.0024678516,0.4481202,0.028986251,0.010158059,0.069408394],"study_design_scores_gemma":[0.0056316745,0.012708223,0.585879,0.00050251704,0.00011201181,0.000004800778,0.0007810515,0.00070848316,0.38984147,0.0032480978,0.00036201876,0.00022061408],"about_ca_topic_score_codex":0.000107394175,"about_ca_topic_score_gemma":0.0000026153953,"teacher_disagreement_score":0.21373296,"about_ca_system_score_codex":0.000011353373,"about_ca_system_score_gemma":0.00007044848,"threshold_uncertainty_score":0.25449556},"labels":[],"label_agreement":null},{"id":"W4313472802","doi":"10.3390/cells12010183","title":"Relationship between Mitochondrial Quality Control Markers, Lower Extremity Tissue Composition, and Physical Performance in Physically Inactive Older Adults","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health; Università Cattolica del Sacro Cuore","keywords":"Mitophagy; Autophagy; Vastus lateralis muscle; Lysosome; Ageing; Adipose tissue; Parkin; PINK1; Sarcopenia; Biology; Endocrinology; Mitochondrion; Internal medicine; Muscle tissue; Medicine; Cell biology; Skeletal muscle; Parkinson's disease; Biochemistry; Enzyme; Apoptosis","score_opus":0.015359297386058034,"score_gpt":0.30131805747870827,"score_spread":0.28595876009265025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313472802","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99821323,0.000041940024,0.00012871624,0.00031820644,0.00014169536,0.0005736363,0.00004347163,0.00007132347,0.00046780604],"genre_scores_gemma":[0.9988703,0.000011737195,0.000045812827,0.00013723897,0.00051159604,0.00003426647,0.00009174444,0.000016446611,0.00028082798],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989752,0.000121916746,0.00020983384,0.0002770843,0.00020734275,0.00020861726],"domain_scores_gemma":[0.99900556,0.0005379575,0.000068938956,0.0002062623,0.000054872133,0.00012640445],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012393724,0.0001378162,0.00031739465,0.000066871195,0.00007397882,0.000012006594,0.00005388654,0.0000861212,0.00003166675],"category_scores_gemma":[0.000037185982,0.00012653894,0.00005919887,0.00024245525,0.000101914025,0.00011999405,0.000020683055,0.00024209458,0.00013353037],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0053459588,0.0012205889,0.94062245,0.00046301482,0.00013557584,0.000094434385,0.0038008718,0.000023117285,0.035758555,0.00030277326,0.0022382925,0.0099943485],"study_design_scores_gemma":[0.004813303,0.000116985786,0.9861801,0.00014978972,0.000056552297,8.6961063e-7,0.00008163578,0.00046105354,0.0076661087,0.00024350156,0.00009629477,0.00013374898],"about_ca_topic_score_codex":0.000018498267,"about_ca_topic_score_gemma":0.0000012988401,"teacher_disagreement_score":0.04555769,"about_ca_system_score_codex":0.000054744694,"about_ca_system_score_gemma":0.00004178411,"threshold_uncertainty_score":0.5160108},"labels":[],"label_agreement":null},{"id":"W4313560911","doi":"10.3389/fnut.2022.1094273","title":"Phosphatidylethanolamine homeostasis under conditions of impaired CDP-ethanolamine pathway or phosphatidylserine decarboxylation","year":2023,"lang":"en","type":"review","venue":"Frontiers in Nutrition","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"Phosphatidylethanolamine; Phosphatidylserine; Neurodegeneration; Endoplasmic reticulum; Ethanolamine; Biology; Hereditary spastic paraplegia; Biochemistry; Cell biology; Chemistry; Phospholipid; Phosphatidylcholine; Medicine; Internal medicine; Disease; Membrane; Gene; Phenotype","score_opus":0.05691906667944754,"score_gpt":0.35236194430463313,"score_spread":0.2954428776251856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313560911","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008787467,0.9925319,0.0006963698,0.000060405,0.0010812011,0.0034175988,0.000989749,0.00023644025,0.00010761909],"genre_scores_gemma":[0.00044497085,0.9884976,0.001693521,0.000068187685,0.00033321173,0.001065038,0.0068166996,0.00018964086,0.0008911174],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966006,0.000190626,0.0014939222,0.0006692245,0.0005415153,0.0005040959],"domain_scores_gemma":[0.9979366,0.00020947057,0.00077400386,0.0006957673,0.0001837142,0.00020046267],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032662504,0.0006540883,0.002818823,0.001338231,0.000077817465,0.000021258662,0.0002400841,0.00070880004,0.00025647023],"category_scores_gemma":[0.00015345994,0.0005618651,0.00072021765,0.0022917746,0.0001846355,0.000210948,0.00006033648,0.00046747524,0.000037794147],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010836351,0.0031927763,0.00017395083,0.17267388,0.0021630842,0.00050735485,0.00020929705,0.000006388248,0.00006782739,0.00043358954,0.012817931,0.8066703],"study_design_scores_gemma":[0.018930119,0.0024712123,0.001702395,0.26105717,0.0056330366,0.00021195081,0.00095874304,0.0004157687,0.0043152194,0.00577538,0.6961754,0.0023536517],"about_ca_topic_score_codex":0.0000340518,"about_ca_topic_score_gemma":0.000014721831,"teacher_disagreement_score":0.80431664,"about_ca_system_score_codex":0.0005349506,"about_ca_system_score_gemma":0.0006003698,"threshold_uncertainty_score":0.99968326},"labels":[],"label_agreement":null},{"id":"W4313573687","doi":"10.26689/jcnr.v7i1.4566","title":"Analysis of Alzheimer’s Disease: From Pathological Mechanism to Therapeutic Approach in Autophagy","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical and Nursing Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Brown University","keywords":"Autophagy; Disease; Mechanism (biology); Pathological; Medicine; Therapeutic approach; Neuroscience; Dysfunctional family; Bioinformatics; Alzheimer's disease; Translational medicine; Population; Drug; Psychology; Psychiatry; Biology; Pathology","score_opus":0.29217997849668287,"score_gpt":0.5398297775643622,"score_spread":0.24764979906767937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313573687","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99321496,0.00276481,0.00022670432,0.0032149283,0.00012953975,0.00021786877,0.000013875476,0.000010532489,0.00020678276],"genre_scores_gemma":[0.99805486,0.0008982405,0.0004729933,0.0002444941,0.00024642158,0.0000055434816,0.00000962013,0.000010574645,0.00005724358],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.996953,0.0006288901,0.0010220744,0.00024649798,0.0008635093,0.00028602735],"domain_scores_gemma":[0.9977713,0.0010260828,0.00016553167,0.00024214042,0.00025462502,0.0005403119],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0049432786,0.00009366549,0.0008719996,0.0009371096,0.000048648017,0.000017114862,0.00015907246,0.00013557242,0.000074219635],"category_scores_gemma":[0.00066082226,0.000062665225,0.0003818429,0.0017150897,0.00028811058,0.000046892037,0.000044971195,0.0006615297,0.0000069697667],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.017932601,0.0068733064,0.4207681,0.00007786996,0.0048507308,0.0030847872,0.0025585578,0.00024612676,0.004824897,0.0039304453,0.0017199169,0.5331326],"study_design_scores_gemma":[0.001363304,0.00086245424,0.96679956,0.0002494783,0.0009003234,0.000006081863,0.00033402117,0.004707054,0.00022758216,0.02444384,0.000045521658,0.00006080251],"about_ca_topic_score_codex":0.000008281221,"about_ca_topic_score_gemma":4.276693e-7,"teacher_disagreement_score":0.5460314,"about_ca_system_score_codex":0.000020324163,"about_ca_system_score_gemma":0.00020719494,"threshold_uncertainty_score":0.28740543},"labels":[],"label_agreement":null},{"id":"W4313648773","doi":"10.1007/s12035-023-03204-2","title":"Correction: Autophagic Molecular Alterations in the Mouse Cerebellum Experimental Autoimmune Encephalomyelitis Model Following Treatment with Cannabidiol and Fluoxetine","year":2023,"lang":"en","type":"erratum","venue":"Molecular Neurobiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Iran University of Medical Sciences","keywords":"Experimental autoimmune encephalomyelitis; Fluoxetine; Cannabidiol; Cerebellum; Neuroscience; Neurology; Encephalomyelitis; Medicine; Biology; Psychiatry; Internal medicine; Central nervous system; Receptor","score_opus":0.012140537013311555,"score_gpt":0.26966216749407373,"score_spread":0.25752163048076215,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313648773","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97155076,0.012018601,0.00052729994,0.002374781,0.006291403,0.002699769,0.000117194955,0.00035169217,0.00406852],"genre_scores_gemma":[0.916294,0.0008695029,0.00014768499,0.0033788907,0.00030254154,0.0010708591,0.0025370752,0.0002339755,0.07516551],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975343,0.00034770428,0.00044229082,0.0008743833,0.0002484249,0.00055294996],"domain_scores_gemma":[0.99884164,0.000053376887,0.0001438547,0.00078552787,0.000047534933,0.0001280792],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011149073,0.0006166318,0.00079992163,0.00027384976,0.00018420615,0.000052493146,0.00022170998,0.00040970615,0.000038310525],"category_scores_gemma":[0.000029601226,0.0004407729,0.00029430052,0.00034561663,0.0001951415,0.000047126876,0.00007676404,0.0007075297,0.000020341933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011020263,0.002153998,0.0001964752,0.0002058658,0.0023789844,0.035207294,0.005529744,0.005089932,0.8097822,0.00059962284,0.13588935,0.0018644962],"study_design_scores_gemma":[0.0597759,0.05241391,0.01922426,0.0031583644,0.008099488,0.01297511,0.0048748907,0.21428019,0.36513188,0.0009957259,0.24941304,0.009657207],"about_ca_topic_score_codex":0.00035093358,"about_ca_topic_score_gemma":0.00005284456,"teacher_disagreement_score":0.44465032,"about_ca_system_score_codex":0.00018482868,"about_ca_system_score_gemma":0.00046317282,"threshold_uncertainty_score":0.9998044},"labels":[],"label_agreement":null},{"id":"W4313679928","doi":"10.1038/s41388-022-02573-7","title":"Chaperone-mediated autophagy promotes PCa survival during ARPI through selective proteome remodeling","year":2023,"lang":"en","type":"article","venue":"Oncogene","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; University of British Columbia","funders":"Terry Fox Foundation","keywords":"Biology; Autophagy; Cell biology; Enzalutamide; Unfolded protein response; Androgen receptor; Downregulation and upregulation; Transcriptome; Proteome; Integrated stress response; Signal transduction; Cancer research; Cell growth; Proteostasis; Cellular stress response; mTORC1; Protein degradation; Prostate cancer; PI3K/AKT/mTOR pathway; Apoptosis; Biochemistry; Gene expression; Cancer; Gene; Translation (biology)","score_opus":0.033782219109477776,"score_gpt":0.3080400134446835,"score_spread":0.27425779433520575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313679928","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934001,0.0007816363,0.00016201942,0.0006328934,0.0002867609,0.0009960218,0.000029917366,0.00086110306,0.0028495423],"genre_scores_gemma":[0.9949234,0.00036269572,0.00068060256,0.0002371411,0.000644947,0.00016864332,0.00016389339,0.00009278241,0.0027258927],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979844,0.00007305268,0.00034574926,0.00052501186,0.0004705855,0.0006011843],"domain_scores_gemma":[0.99907553,0.00006834808,0.000105661966,0.00040053533,0.00015144936,0.00019846982],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002479754,0.0002784044,0.00045342682,0.00014715905,0.00022231978,0.000022471539,0.00014038417,0.00016782717,0.00022478813],"category_scores_gemma":[0.0001585013,0.0002480718,0.00015624918,0.00087563717,0.00006987641,0.00016549246,0.00007553738,0.00026942376,0.00065191736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00056504644,0.0003017655,0.001151352,0.00019393585,0.00036231236,0.00055256655,0.0021217887,0.00011574427,0.99230754,0.000109434266,0.00016795598,0.0020505649],"study_design_scores_gemma":[0.0049607987,0.00056821416,0.03366576,0.00026000757,0.0001595593,0.000108320266,0.0003327561,0.0059683537,0.9502363,0.0015156192,0.0016800782,0.0005442087],"about_ca_topic_score_codex":0.000047805464,"about_ca_topic_score_gemma":0.000006285482,"teacher_disagreement_score":0.042071212,"about_ca_system_score_codex":0.00015150844,"about_ca_system_score_gemma":0.00025623245,"threshold_uncertainty_score":0.99999714},"labels":[],"label_agreement":null},{"id":"W4313681525","doi":"10.1101/2023.01.04.522687","title":"Autophagy disruption reduces mTORC1 activation leading to retinal ganglion cell neurodegeneration associated with glaucoma","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Eye Institute; National Center for Advancing Translational Sciences; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Glaucoma Research Foundation; School of Medicine, Indiana University; National Institutes of Health; BrightFocus Foundation; Eli Lilly and Company","keywords":"Autophagy; Neurodegeneration; mTORC1; Cell biology; PI3K/AKT/mTOR pathway; Biology; Mechanistic target of rapamycin; Retinal ganglion cell; Neuroscience; Signal transduction; Medicine; Retina; Internal medicine","score_opus":0.020278888915782178,"score_gpt":0.2512853811743551,"score_spread":0.23100649225857295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313681525","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99305576,0.00014122587,0.0028841533,0.00053613173,0.0008758248,0.0013193648,0.00008600569,0.0010863545,0.000015200694],"genre_scores_gemma":[0.9968643,0.00007596456,0.00086954405,0.00043504042,0.0010557628,0.00031870266,0.000014358371,0.00025063835,0.000115643306],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968157,0.00019835455,0.00055063167,0.001148705,0.00072821876,0.00055838807],"domain_scores_gemma":[0.9975016,0.000081824466,0.00052646466,0.000881993,0.00061102916,0.0003970598],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050968013,0.00059656537,0.00064073206,0.00052417314,0.00024981613,0.00019989247,0.00025047685,0.0005321586,0.0000422416],"category_scores_gemma":[0.00033750874,0.0005905916,0.00016029115,0.0009503713,0.00006269535,0.00022317936,0.00015466455,0.0007410682,0.00013990753],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003723178,0.00030908416,0.0065567903,0.00024305114,0.00018668108,0.00016694727,0.000044930384,0.000234689,0.99109703,0.00010389725,0.0006794567,0.0000051393836],"study_design_scores_gemma":[0.00082434196,0.00031695538,0.28221226,0.0009070883,0.00024616884,3.4758436e-8,0.000005085963,0.0008364098,0.7139782,0.000002259169,0.00017951435,0.0004917143],"about_ca_topic_score_codex":0.000029093462,"about_ca_topic_score_gemma":0.0000022646748,"teacher_disagreement_score":0.27711883,"about_ca_system_score_codex":0.00067136885,"about_ca_system_score_gemma":0.0006189677,"threshold_uncertainty_score":0.99965453},"labels":[],"label_agreement":null},{"id":"W4313893662","doi":"10.3389/fgene.2022.1012706","title":"Regulation of autophagy, lipid metabolism, and neurodegenerative pathology by heparan sulfate proteoglycans","year":2023,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"National Institute on Aging; National Institutes of Health; Pennsylvania State University; University of Pennsylvania","keywords":"Cell biology; Autophagy; Biology; Neurodegeneration; Cellular compartment; Lipid metabolism; Biogenesis; Biochemistry; Cell; Disease","score_opus":0.029451362357821982,"score_gpt":0.3170773909747708,"score_spread":0.2876260286169488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313893662","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.003071178,0.9929572,0.00091119437,0.000029740073,0.0008612484,0.0018101567,0.00025918052,0.000046999736,0.000053150274],"genre_scores_gemma":[0.00008264516,0.99333906,0.004542356,0.00004922702,0.00022578523,0.00019912234,0.0003817217,0.000104898056,0.0010751765],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99789053,0.00030627014,0.00075921096,0.00051793206,0.00022793114,0.0002980957],"domain_scores_gemma":[0.99893004,0.000036851972,0.0003782016,0.00046510238,0.00006377577,0.00012603207],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021610309,0.00039309595,0.0019368626,0.00036256624,0.000037434475,0.000010745315,0.00015204024,0.00042165312,0.000013923597],"category_scores_gemma":[0.00004690417,0.00034353454,0.00022364258,0.00045803556,0.00022354523,0.00002690479,0.00006514999,0.00032680825,0.0000049457417],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010267284,0.00015622082,0.00019429538,0.009398542,0.00053067465,0.0000953204,0.0003370995,0.000015622396,0.00023254436,0.000064842054,0.009228338,0.9796438],"study_design_scores_gemma":[0.0015261858,0.00030237582,0.0017347687,0.0028249451,0.0019822614,0.000052396583,0.000035832378,0.00047899692,0.0013937651,0.0006451255,0.988542,0.00048132744],"about_ca_topic_score_codex":0.000006319252,"about_ca_topic_score_gemma":0.000002036192,"teacher_disagreement_score":0.9793137,"about_ca_system_score_codex":0.00005301211,"about_ca_system_score_gemma":0.00026090196,"threshold_uncertainty_score":0.99990165},"labels":[],"label_agreement":null},{"id":"W4315650461","doi":"10.20944/preprints202301.0183.v1","title":"Regulation of Autophagy via Carbohydrate and Lipid Metabolism in Cancer","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Max Rady College of Medicine, University of Manitoba","keywords":"Autophagy; Organelle; Cell biology; Lipid metabolism; Cancer cell; Carcinogenesis; Metabolic pathway; Biochemistry; Biology; Metabolism; Cell metabolism; Cell; Glycolysis; Lipid droplet; Carbohydrate metabolism; Chemistry; Cancer; Apoptosis; Gene","score_opus":0.10375928039400156,"score_gpt":0.37334860868619923,"score_spread":0.26958932829219767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4315650461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950245,0.0019436245,0.000049584054,0.0005055743,0.0008002331,0.00083483546,0.000035912486,0.00014413304,0.000661589],"genre_scores_gemma":[0.9952178,0.0021878148,0.0000678083,0.00012160153,0.00033216138,0.00027752868,0.000093288625,0.000063815234,0.0016382061],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9979729,0.00010815929,0.00060382293,0.0007279658,0.00032200114,0.00026515318],"domain_scores_gemma":[0.9984562,0.00004988262,0.0003194903,0.0009026579,0.00012466352,0.00014710946],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043294992,0.0002954542,0.0007640394,0.0003463409,0.000028293593,0.000005802312,0.00017973226,0.0003584438,0.000656129],"category_scores_gemma":[0.000090104855,0.00029329152,0.00016453814,0.00024641227,0.00011452122,0.000056602898,0.0005899754,0.000546124,0.000096290074],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004565848,0.0003175833,0.59690595,0.0012200106,0.00065546605,0.000060029997,0.0022609853,0.0014955531,0.39284378,0.00043933635,0.000026338923,0.0033184185],"study_design_scores_gemma":[0.00087114,0.000011143513,0.85804534,0.0004299019,0.00020483752,0.0000024246356,0.000018489329,0.0014808514,0.1337729,0.004590422,0.00038523562,0.00018731465],"about_ca_topic_score_codex":0.0019958585,"about_ca_topic_score_gemma":0.00007376492,"teacher_disagreement_score":0.26113942,"about_ca_system_score_codex":0.00010372774,"about_ca_system_score_gemma":0.0002672909,"threshold_uncertainty_score":0.9999519},"labels":[],"label_agreement":null},{"id":"W4315752239","doi":"10.1080/19382014.2022.2163829","title":"A small molecule improves diabetes in mice expressing human islet amyloid polypeptide","year":2023,"lang":"en","type":"article","venue":"Islets","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Stem Cell Network; BC Children's Hospital","keywords":"Islet; Autophagy; Amyloid (mycology); Cell biology; Beta cell; Diabetes mellitus; Fibril; Enhancer; Inflammation; Homeostasis; Oligomer; Chemistry; Biology; Endocrinology; Biochemistry; Immunology; Apoptosis","score_opus":0.02337758130054011,"score_gpt":0.28344202633533994,"score_spread":0.2600644450347998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4315752239","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948458,0.00056630414,0.0000037089153,0.00052295264,0.00011156811,0.0002416957,0.000008108196,0.00023093246,0.003468896],"genre_scores_gemma":[0.99625397,0.000028057226,0.00009459431,0.0015849812,0.00020929381,0.00005163378,0.00004467722,0.000044194654,0.0016885921],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886405,0.00004016249,0.00022502254,0.00028945823,0.00016096937,0.00042031452],"domain_scores_gemma":[0.9994671,0.00005252478,0.000055213524,0.00028476623,0.000024334875,0.00011609056],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012953524,0.0001625782,0.0002512127,0.00020123538,0.000075918935,0.000028385653,0.00012272075,0.000069991635,0.00009754835],"category_scores_gemma":[0.00004502123,0.00015196684,0.000098681914,0.00031848208,0.000060200848,0.00006528634,0.00005867187,0.00017277298,0.00020048824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003399506,0.000120357974,0.0029691714,0.000059532536,0.000038637543,0.0002847511,0.00048451856,0.0000025367046,0.9929261,0.000056591824,0.0013818645,0.0016419445],"study_design_scores_gemma":[0.0023270368,0.00021132393,0.07425755,0.00036215695,0.000049594928,0.00000572715,0.00024780768,0.0006244089,0.91884726,0.0009363959,0.0018346251,0.0002960942],"about_ca_topic_score_codex":0.00008426533,"about_ca_topic_score_gemma":0.0000125477345,"teacher_disagreement_score":0.07407883,"about_ca_system_score_codex":0.000037555918,"about_ca_system_score_gemma":0.00004236469,"threshold_uncertainty_score":0.6197028},"labels":[],"label_agreement":null},{"id":"W4316036088","doi":"10.1615/critrevoncog.2023047542","title":"Bioactive Compounds from Curcuma amada and Their Effect on Acute Myeloid Leukemia","year":2022,"lang":"en","type":"review","venue":"Critical Reviews™ in Oncogenesis","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vineland Research and Innovation Centre; University of Guelph; University of Calgary","funders":"","keywords":"Myeloid leukemia; Apoptosis; Autophagy; Leukemia; Viability assay; Cancer; Cell cycle checkpoint; Cancer research; Cell cycle; Antioxidant; Pharmacology; Myeloid; Cancer cell; Chemistry; Biology; Medicine; Immunology; Internal medicine; Biochemistry","score_opus":0.06141800547916383,"score_gpt":0.3956302389099615,"score_spread":0.3342122334307977,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4316036088","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007820506,0.99390453,0.00001427555,0.00009951408,0.00046260166,0.0023980015,0.0005413786,0.000071196424,0.0017264414],"genre_scores_gemma":[0.000224116,0.99550784,0.00008643692,0.0013194832,0.000491708,0.0014102153,0.0006955028,0.00015171578,0.00011295921],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99500334,0.0015940521,0.0012146877,0.0011718713,0.00041626862,0.0005998066],"domain_scores_gemma":[0.9927588,0.005423424,0.00022735176,0.0010423976,0.000038770035,0.00050925807],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00081169273,0.0010491519,0.00560608,0.00030821192,0.00018211913,0.00005251878,0.00039122842,0.00044989676,0.001391622],"category_scores_gemma":[0.001099392,0.00069422426,0.0013560865,0.00063065183,0.00034723937,0.00007692924,0.00021574012,0.0010969285,0.00024623718],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017529838,0.00020344801,0.000014652268,0.012023401,0.0005451866,0.00047040707,0.000045231922,1.3354491e-8,0.000014265652,0.00019169784,0.000720222,0.9855962],"study_design_scores_gemma":[0.0007898225,0.0011335014,0.000040888037,0.024079889,0.003795954,0.00011781062,0.000017891392,0.0000040564573,0.00006526167,0.00021847857,0.9691568,0.0005796523],"about_ca_topic_score_codex":0.00006470171,"about_ca_topic_score_gemma":0.000003757323,"teacher_disagreement_score":0.9850165,"about_ca_system_score_codex":0.0012016302,"about_ca_system_score_gemma":0.0005500237,"threshold_uncertainty_score":0.9995509},"labels":[],"label_agreement":null},{"id":"W4316494230","doi":"10.3389/fnmol.2022.1078441","title":"Brain-protective mechanisms of autophagy associated circRNAs: Kick starting self-cleaning mode in brain cells via circRNAs as a potential therapeutic approach for neurodegenerative diseases","year":2023,"lang":"en","type":"review","venue":"Frontiers in Molecular Neuroscience","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Autophagy; Neurodegeneration; Neuroscience; Biology; Amyotrophic lateral sclerosis; Mechanism (biology); Disease; Medicine; Pathology; Genetics","score_opus":0.023216735066852498,"score_gpt":0.31447915429339934,"score_spread":0.29126241922654683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4316494230","genre_codex":"methods","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010073055,0.35458586,0.63619703,0.00007592719,0.0012010207,0.006327959,0.00032954398,0.00024672982,0.000028634899],"genre_scores_gemma":[0.07858709,0.84894806,0.046071287,0.01423743,0.0005296588,0.0069889347,0.0014439904,0.002224654,0.0009688794],"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99405473,0.0010993195,0.0012235957,0.0016659801,0.00094599515,0.0010104039],"domain_scores_gemma":[0.9977616,0.00024346045,0.00089227327,0.0006976434,0.00012155566,0.00028343056],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00077976147,0.0007963763,0.0023599039,0.0010311311,0.00018844026,0.000076985656,0.00079660665,0.00040788055,0.0000034992338],"category_scores_gemma":[0.0008662064,0.0007812333,0.00074446696,0.0021396934,0.0002555986,0.00017365074,0.00019607245,0.0008506648,0.0000024646445],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016458625,0.009962631,0.000074500516,0.04535524,0.0027580904,0.009665019,0.0043618334,0.034571327,0.4382711,0.0032956442,0.001673315,0.44836542],"study_design_scores_gemma":[0.01663083,0.0066192104,0.000489086,0.01682412,0.006508809,0.000208242,0.0012829769,0.8219408,0.057437416,0.058741916,0.007214623,0.006101997],"about_ca_topic_score_codex":0.000052721633,"about_ca_topic_score_gemma":0.0000018942523,"teacher_disagreement_score":0.78736943,"about_ca_system_score_codex":0.00044633946,"about_ca_system_score_gemma":0.0010352687,"threshold_uncertainty_score":0.99946386},"labels":[],"label_agreement":null},{"id":"W4316668850","doi":"10.3389/fphar.2022.1053602","title":"Perturbed autophagy intervenes systemic lupus erythematosus by active ingredients of traditional Chinese medicine","year":2023,"lang":"en","type":"review","venue":"Frontiers in Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Wuhan Science and Technology Project; Hubei University; Hubei University of Technology; National Natural Science Foundation of China; University of Alberta","keywords":"Autophagy; Immune system; Autoantibody; Medicine; Immunology; Mechanism (biology); Systemic lupus erythematosus; Disease; Traditional Chinese medicine; Autoimmune disease; Homeostasis; Autoimmunity; Lupus erythematosus; Apoptosis; Biology; Antibody; Internal medicine; Pathology","score_opus":0.048628521532240496,"score_gpt":0.373248942772267,"score_spread":0.3246204212400265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4316668850","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0035983261,0.9797859,0.00012203198,0.000073914816,0.013722169,0.001770253,0.0005629391,0.000118626,0.00024582513],"genre_scores_gemma":[0.0014223794,0.9932532,0.00007377057,0.00020822659,0.0010515796,0.0006425401,0.0012177706,0.0001353944,0.001995149],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99657,0.0004486371,0.0014182669,0.00065521616,0.000415414,0.0004924846],"domain_scores_gemma":[0.9980076,0.0005246184,0.00081088714,0.00031169437,0.00009939478,0.00024583697],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035596814,0.00066093163,0.0040567135,0.0010500364,0.000048105114,0.0000049766063,0.00045221206,0.00055725337,0.00046806957],"category_scores_gemma":[0.00015603495,0.00048775072,0.00065295486,0.00086518103,0.00044968436,0.000109080276,0.00008758327,0.0007562976,0.000021938267],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015862924,0.0018088808,0.0007405795,0.090223014,0.0097660925,0.0018506688,0.0016274694,0.000003187644,0.00021545346,0.000095687465,0.54455525,0.3475274],"study_design_scores_gemma":[0.021875223,0.002071793,0.00020288205,0.07196468,0.010582509,0.0046317927,0.0007588815,0.00042320622,0.00020459115,0.0017119474,0.88412666,0.0014458181],"about_ca_topic_score_codex":0.000015533073,"about_ca_topic_score_gemma":6.321554e-7,"teacher_disagreement_score":0.34608158,"about_ca_system_score_codex":0.00053671707,"about_ca_system_score_gemma":0.00041546597,"threshold_uncertainty_score":0.9997574},"labels":[],"label_agreement":null},{"id":"W4317209889","doi":"10.1101/2023.01.17.524124","title":"Autophagy mediates cancer cell resistance to doxorubicin induced by the Programmed Death 1/Programmed Death Ligand 1 immune checkpoint axis","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Terry Fox Research Institute","keywords":"Autophagy; Programmed cell death; Cancer research; Cancer cell; Cell biology; MAPK/ERK pathway; Signal transduction; Phosphorylation; Kinase; ATG5; Biology; Chemistry; Apoptosis; Cancer; Biochemistry","score_opus":0.026211608125397735,"score_gpt":0.27145154063003646,"score_spread":0.2452399325046387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317209889","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96478826,0.022717383,0.00010634307,0.0036699392,0.0017255644,0.0047420054,0.00074961595,0.0014652514,0.000035658977],"genre_scores_gemma":[0.98860997,0.0027994795,0.0013539565,0.0010642624,0.0010154878,0.0043862932,0.000010894055,0.0004609107,0.00029873243],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9935675,0.0002336189,0.0014622699,0.001998975,0.001148399,0.0015891971],"domain_scores_gemma":[0.9941024,0.00021949444,0.00085199747,0.002993731,0.0007716709,0.001060682],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001408803,0.0012666504,0.0015280446,0.00026923983,0.00040418614,0.0003433357,0.0012154224,0.00095331157,0.000085132095],"category_scores_gemma":[0.00043669128,0.0010170077,0.0005570206,0.0011307347,0.00016855932,0.00013560873,0.0007006525,0.0015364183,0.00017150294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00094798114,0.000883999,0.0032624123,0.0011331252,0.0013832366,0.00029375858,0.00018200133,0.000010573669,0.98936856,0.00012897249,0.0023595656,0.000045812958],"study_design_scores_gemma":[0.0026084804,0.00025434437,0.11032179,0.0010064326,0.00068646466,4.2148223e-8,0.000026361027,0.000054570428,0.8724667,0.000011121504,0.011504712,0.001058989],"about_ca_topic_score_codex":0.0018177534,"about_ca_topic_score_gemma":0.00010652707,"teacher_disagreement_score":0.11690187,"about_ca_system_score_codex":0.0009927825,"about_ca_system_score_gemma":0.0017591113,"threshold_uncertainty_score":0.999228},"labels":[],"label_agreement":null},{"id":"W4317435118","doi":"10.3390/plants12030443","title":"Chloroplast Envelopes Play a Role in the Formation of Autophagy-Related Structures in Plants","year":2023,"lang":"en","type":"article","venue":"Plants","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Cell biology; Cytoplasm; ATG8; Vacuole; Autophagosome; Organelle; Chloroplast; Biology; Biogenesis; Chemistry; Biochemistry; Apoptosis","score_opus":0.014097360479931789,"score_gpt":0.2652751900970517,"score_spread":0.25117782961711993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317435118","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975302,0.00034831636,0.0000012811179,0.00009552737,0.00007957702,0.00027743407,0.00007719305,0.000043154618,0.0015472709],"genre_scores_gemma":[0.9992119,0.00028501125,0.000010106939,0.00014628547,0.000023848843,0.000019287614,0.00022322513,0.000008858019,0.0000714903],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99912477,0.000048581027,0.00027967268,0.000114324925,0.00023303025,0.0001995993],"domain_scores_gemma":[0.99962616,0.000110257744,0.00007223447,0.00014926672,0.000008524721,0.000033528268],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020086709,0.000099353056,0.00019654736,0.00024191315,0.000027128764,0.0000067227274,0.000113998816,0.00008281166,0.00008639321],"category_scores_gemma":[0.000033518358,0.000066149514,0.00003168371,0.00027309824,0.000025772912,0.000083454186,0.000017373412,0.00014955444,0.00007542776],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009429034,0.0022730473,0.39987352,0.0013460848,0.00081410195,0.0072897915,0.2737584,0.0034410376,0.15444496,0.0054295487,0.012735514,0.12916495],"study_design_scores_gemma":[0.0024482883,0.00007484201,0.9562354,0.00018956157,0.000011223161,0.00008689516,0.0017153965,0.0032092773,0.032545943,0.0029497475,0.00043884962,0.000094576404],"about_ca_topic_score_codex":0.00007348447,"about_ca_topic_score_gemma":0.00007978003,"teacher_disagreement_score":0.55636185,"about_ca_system_score_codex":0.000021585547,"about_ca_system_score_gemma":0.000041717754,"threshold_uncertainty_score":0.26974988},"labels":[],"label_agreement":null},{"id":"W4317815041","doi":"10.1186/s12931-023-02332-6","title":"RAGE inhibition alleviates lipopolysaccharides-induced lung injury via directly suppressing autophagic apoptosis of type II alveolar epithelial cells","year":2023,"lang":"en","type":"article","venue":"Respiratory Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Science and Technology Commission of Shanghai Municipality; National Natural Science Foundation of China","keywords":"Rage (emotion); Autophagy; Bronchoalveolar lavage; TUNEL assay; Apoptosis; A549 cell; Inflammation; Receptor; Alveolar Epithelium; Lung; Chemistry; Cancer research; Immunology; Medicine; Biology; Internal medicine; Biochemistry","score_opus":0.07305435189386426,"score_gpt":0.3871561129762004,"score_spread":0.3141017610823361,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317815041","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99629414,0.0013716534,0.000014995239,0.0002016287,0.0003121855,0.0007557882,0.000050160917,0.00026511075,0.00073435914],"genre_scores_gemma":[0.997973,0.00030714838,0.00003518723,0.00024723884,0.0004935373,0.000067919034,0.00004108385,0.000088773566,0.00074610446],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9961156,0.0006016479,0.0005772933,0.00056783535,0.0013181434,0.00081942946],"domain_scores_gemma":[0.99785304,0.00032937762,0.00013592477,0.00074739405,0.00057480653,0.0003594531],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0023515406,0.00026506535,0.00053231884,0.00095904735,0.0004955388,0.00004776122,0.00025445304,0.00028569176,0.00093041296],"category_scores_gemma":[0.00035405112,0.00024154615,0.00023118987,0.0019148107,0.00024168746,0.00023179816,0.00029744513,0.0007506882,0.000403261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007701546,0.00026802247,0.00059740647,0.000302141,0.00016411158,0.00010191262,0.00048374623,0.000006913774,0.98402524,0.000041953303,0.004194065,0.009044325],"study_design_scores_gemma":[0.0012006736,0.0010814187,0.0026022107,0.00027537593,0.000060355545,0.000002591661,0.00010380478,0.0009198958,0.9904233,0.00028594965,0.0028381785,0.00020623706],"about_ca_topic_score_codex":0.00007449895,"about_ca_topic_score_gemma":0.0000015945926,"teacher_disagreement_score":0.008838088,"about_ca_system_score_codex":0.00017113524,"about_ca_system_score_gemma":0.0005664112,"threshold_uncertainty_score":0.9999829},"labels":[],"label_agreement":null},{"id":"W4318040817","doi":"10.21203/rs.3.rs-2496824/v1","title":"Peroxisome loss leads to increased mitochondrial biogenesis and reduced autophagy to preserve mitochondrial function","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation","funders":"University of Toronto; Canadian Institutes of Health Research; Hospital for Sick Children; Genome British Columbia; University of Victoria","keywords":"Autophagy; Mitochondrial biogenesis; Peroxisome; Cell biology; Biogenesis; Function (biology); Mitochondrion; Organelle biogenesis; Chemistry; Biology; Biochemistry; Gene; Apoptosis","score_opus":0.07075639796652572,"score_gpt":0.39148878998007725,"score_spread":0.3207323920135515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318040817","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9827979,0.0012728515,0.00027739446,0.0048505636,0.0027052525,0.006583719,0.0007734142,0.0005192614,0.00021965132],"genre_scores_gemma":[0.9740736,0.00052741595,0.0012485067,0.0005550499,0.009002908,0.0034605642,0.0012747371,0.00034703306,0.009510169],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.992661,0.0008278994,0.0007317431,0.001982085,0.0024205698,0.0013767142],"domain_scores_gemma":[0.9942837,0.000547906,0.0001152185,0.001972051,0.0011190899,0.0019620357],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009035324,0.0006598403,0.0010786453,0.0018591926,0.00042379645,0.00030509656,0.00064569816,0.000913107,0.0006579848],"category_scores_gemma":[0.0021596525,0.0006246412,0.00045793608,0.0014347666,0.00022860001,0.00011895481,0.0019112165,0.0015226969,0.0011915799],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.039919715,0.0016078327,0.0060548335,0.0051203254,0.001749244,0.0019603597,0.0027713606,0.00043216906,0.7910957,0.00040185807,0.14228968,0.006596962],"study_design_scores_gemma":[0.019132711,0.014233238,0.6500303,0.008721311,0.0011968487,0.00011265275,0.0013738115,0.00088576484,0.24502172,0.0074668108,0.048370734,0.0034541048],"about_ca_topic_score_codex":0.0020789057,"about_ca_topic_score_gemma":0.00016078305,"teacher_disagreement_score":0.64397544,"about_ca_system_score_codex":0.0005602207,"about_ca_system_score_gemma":0.0014042697,"threshold_uncertainty_score":0.9996205},"labels":[],"label_agreement":null},{"id":"W4318562430","doi":"10.1002/ptr.7738","title":"Targeting regulated cell death with plant natural compounds for cancer therapy: A revisited review of apoptosis, autophagy‐dependent cell death, and necroptosis","year":2023,"lang":"en","type":"review","venue":"Phytotherapy Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Necroptosis; Autophagy; Programmed cell death; Apoptosis; Cancer cell; Cell biology; Cancer; Biology; Small molecule; Cancer research; Biochemistry","score_opus":0.11174595932359063,"score_gpt":0.41910170178300765,"score_spread":0.307355742459417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318562430","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002018691,0.98809415,0.000013602767,0.00015838642,0.0001325788,0.008399608,0.0008051581,0.00016148637,0.00021636559],"genre_scores_gemma":[0.0004140862,0.99107313,0.000544595,0.00038597613,0.00045924258,0.0024285286,0.0012894155,0.00041977494,0.0029852309],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.9937856,0.000813909,0.0013655585,0.0012933718,0.0015379018,0.001203629],"domain_scores_gemma":[0.9957568,0.0010327664,0.0007835807,0.0010776176,0.00094275794,0.00040647868],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0022404466,0.00096053554,0.0039280783,0.00072439556,0.0003572661,0.000090673835,0.000613791,0.0004300166,0.0002454263],"category_scores_gemma":[0.00006653962,0.0006400399,0.00075891335,0.0014966346,0.00023346386,0.000106720974,0.000118841475,0.0013232378,0.000016275402],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0031662083,0.001273929,0.00017073892,0.695945,0.004486482,0.00010898165,0.00038775746,0.0000015380324,0.0044371537,0.00013666511,0.013629398,0.27625614],"study_design_scores_gemma":[0.00552588,0.0018211051,0.000057968464,0.2257452,0.0013941198,0.000043801287,0.00004254152,0.00012773534,0.008942938,0.00007701655,0.75519925,0.0010224573],"about_ca_topic_score_codex":0.00019557787,"about_ca_topic_score_gemma":0.0000037292336,"teacher_disagreement_score":0.7415698,"about_ca_system_score_codex":0.0003588672,"about_ca_system_score_gemma":0.0013519048,"threshold_uncertainty_score":0.99960506},"labels":[],"label_agreement":null},{"id":"W4318701118","doi":"10.32920/21982901","title":"The Lysosome Signaling Platform: Adapting With the Times","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Lysosome; Autophagy; Cell biology; mTORC1; Endocytosis; ATG16L1; Cellular adaptation; TFEB; Biology; Organelle; Inflammasome; Signal transduction; Inflammation; Cell; Biochemistry; PI3K/AKT/mTOR pathway; Immunology","score_opus":0.04726697997185854,"score_gpt":0.2947391284385271,"score_spread":0.2474721484666686,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318701118","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90109396,0.0068626655,0.0031478463,0.03289584,0.0009276748,0.0027678625,0.000027183101,0.0014781127,0.050798878],"genre_scores_gemma":[0.9555606,0.0003693017,0.0003323044,0.0013768673,0.00073568395,0.00013737199,0.000041712963,0.00007917748,0.041366957],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987282,0.00003120454,0.00022293863,0.00029641364,0.00041792844,0.00030332676],"domain_scores_gemma":[0.9985261,0.000446346,0.00014187918,0.00071923557,0.00007964548,0.00008679592],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004512826,0.00024005145,0.00027322865,0.000040648305,0.00037950685,0.000103613376,0.00032080553,0.00013556625,0.0002724585],"category_scores_gemma":[0.00003613016,0.0000917736,0.0001687585,0.00011542546,0.00012931804,0.000027866714,0.00026236504,0.00066834537,0.00018771426],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015112009,0.0014763207,0.01492558,0.004334017,0.049868032,0.0053363,0.030999852,0.040832724,0.0120597,0.20184611,0.38037312,0.24283624],"study_design_scores_gemma":[0.022894846,0.004243785,0.06912288,0.015908163,0.012318518,0.00081501686,0.07634908,0.113359675,0.107786655,0.24146333,0.32744935,0.008288695],"about_ca_topic_score_codex":0.00008617552,"about_ca_topic_score_gemma":0.000020737247,"teacher_disagreement_score":0.23454754,"about_ca_system_score_codex":0.000037968406,"about_ca_system_score_gemma":0.00026785777,"threshold_uncertainty_score":0.3742419},"labels":[],"label_agreement":null},{"id":"W4318701124","doi":"10.32920/21982895.v1","title":"Lysosome remodelling and adaptation during phagocyte activation","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institutes of Health Research; Toronto Metropolitan University; Natural Sciences and Engineering Research Council of Canada","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canadian Institutes of Health Research; Government of Ontario","keywords":"TFEB; Lysosome; Cell biology; Autophagy; Phagocytosis; Biology; Phagocyte; Cellular adaptation; Antigen presentation; Endocytosis; Immune system; Cell; Immunology; T cell; Biochemistry; Gene","score_opus":0.08277131359421079,"score_gpt":0.3104084458096898,"score_spread":0.227637132215479,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318701124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98065495,0.00031548727,0.016361926,0.00057168887,0.00018734798,0.0004304645,0.000004830708,0.0003761785,0.0010971456],"genre_scores_gemma":[0.98932076,0.0011749143,0.0029438436,0.00017101345,0.00033911166,0.000036770667,0.0001496455,0.000046865258,0.005817084],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9990573,0.000018179584,0.0002349784,0.00034999134,0.0002015641,0.00013796697],"domain_scores_gemma":[0.9994445,0.00003370994,0.00010711914,0.00026321926,0.00006103191,0.000090443114],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009745703,0.00016280697,0.00023780916,0.00015811383,0.000064343236,0.000028887613,0.0000419343,0.00018518104,0.00006987106],"category_scores_gemma":[0.000026982772,0.00014969167,0.000073812305,0.00007280753,0.000022545764,0.0000689212,0.00009629219,0.0002772372,0.000034631117],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01247783,0.0018901257,0.018644914,0.025067113,0.008890177,0.001518252,0.028940512,0.18268625,0.4678037,0.017291619,0.001976985,0.23281252],"study_design_scores_gemma":[0.0055451156,0.0001583265,0.120814435,0.0028804033,0.000638105,0.000044418804,0.0010634675,0.63894117,0.18489003,0.04366098,0.00034843638,0.00101514],"about_ca_topic_score_codex":0.00006252131,"about_ca_topic_score_gemma":0.0000020086595,"teacher_disagreement_score":0.45625487,"about_ca_system_score_codex":0.00006911592,"about_ca_system_score_gemma":0.00008663818,"threshold_uncertainty_score":0.61042494},"labels":[],"label_agreement":null},{"id":"W4318701296","doi":"10.32920/21982919","title":"Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Ontario; Yale University","keywords":"Lysosome; TFEB; Cell biology; Autophagy; Endocytosis; Biology; Mechanistic target of rapamycin; PI3K/AKT/mTOR pathway; Biochemistry; Cell; Signal transduction; Enzyme","score_opus":0.03581083531569235,"score_gpt":0.29486056179638104,"score_spread":0.2590497264806887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318701296","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99100834,0.0005913442,0.00019861781,0.0022136534,0.0008836788,0.0018668239,0.00006616662,0.00032776795,0.0028435811],"genre_scores_gemma":[0.991667,0.0010483594,0.00027795648,0.00078225776,0.00062107254,0.0002508485,0.00010789836,0.00008069918,0.0051639634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99739796,0.000061230494,0.00068714714,0.000652005,0.0007998771,0.00040176834],"domain_scores_gemma":[0.998122,0.000036435686,0.00040549468,0.0010729902,0.00023445247,0.0001286325],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021033021,0.00041590954,0.0006369496,0.00014073272,0.00013202052,0.000028938483,0.00031608882,0.00032343794,0.00043903769],"category_scores_gemma":[0.00008174094,0.0002877823,0.00047464643,0.00036631693,0.00019559641,0.00009825843,0.00087150634,0.0006447363,0.0001225653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040649357,0.009680418,0.11716731,0.044883188,0.0063166483,0.0014339837,0.018827407,0.0012828261,0.7437801,0.028639417,0.020753812,0.0031699706],"study_design_scores_gemma":[0.003522063,0.00021668836,0.15010361,0.005928334,0.00069706934,0.0000321999,0.00083952834,0.0002027775,0.8284939,0.008618866,0.0006754362,0.0006695269],"about_ca_topic_score_codex":0.00009731937,"about_ca_topic_score_gemma":0.000008307153,"teacher_disagreement_score":0.08471382,"about_ca_system_score_codex":0.00020003266,"about_ca_system_score_gemma":0.00034889675,"threshold_uncertainty_score":0.99995744},"labels":[],"label_agreement":null},{"id":"W4318704921","doi":"10.32920/21982919.v1","title":"Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Ontario; Yale University","keywords":"Lysosome; TFEB; Cell biology; Autophagy; Endocytosis; Biology; Mechanistic target of rapamycin; PI3K/AKT/mTOR pathway; Biochemistry; Cell; Signal transduction; Enzyme","score_opus":0.03581083531569235,"score_gpt":0.29486056179638104,"score_spread":0.2590497264806887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318704921","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99100834,0.0005913442,0.00019861781,0.0022136534,0.0008836788,0.0018668239,0.00006616662,0.00032776795,0.0028435811],"genre_scores_gemma":[0.991667,0.0010483594,0.00027795648,0.00078225776,0.00062107254,0.0002508485,0.00010789836,0.00008069918,0.0051639634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99739796,0.000061230494,0.00068714714,0.000652005,0.0007998771,0.00040176834],"domain_scores_gemma":[0.998122,0.000036435686,0.00040549468,0.0010729902,0.00023445247,0.0001286325],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021033021,0.00041590954,0.0006369496,0.00014073272,0.00013202052,0.000028938483,0.00031608882,0.00032343794,0.00043903769],"category_scores_gemma":[0.00008174094,0.0002877823,0.00047464643,0.00036631693,0.00019559641,0.00009825843,0.00087150634,0.0006447363,0.0001225653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040649357,0.009680418,0.11716731,0.044883188,0.0063166483,0.0014339837,0.018827407,0.0012828261,0.7437801,0.028639417,0.020753812,0.0031699706],"study_design_scores_gemma":[0.003522063,0.00021668836,0.15010361,0.005928334,0.00069706934,0.0000321999,0.00083952834,0.0002027775,0.8284939,0.008618866,0.0006754362,0.0006695269],"about_ca_topic_score_codex":0.00009731937,"about_ca_topic_score_gemma":0.000008307153,"teacher_disagreement_score":0.08471382,"about_ca_system_score_codex":0.00020003266,"about_ca_system_score_gemma":0.00034889675,"threshold_uncertainty_score":0.99995744},"labels":[],"label_agreement":null},{"id":"W4318705146","doi":"10.32920/21982901.v1","title":"The Lysosome Signaling Platform: Adapting With the Times","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Lysosome; Autophagy; Cell biology; mTORC1; Endocytosis; ATG16L1; Cellular adaptation; TFEB; Biology; Organelle; Inflammasome; Signal transduction; Inflammation; Cell; Biochemistry; PI3K/AKT/mTOR pathway; Immunology; Enzyme","score_opus":0.04726697997185854,"score_gpt":0.2947391284385271,"score_spread":0.2474721484666686,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318705146","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90109396,0.0068626655,0.0031478463,0.03289584,0.0009276748,0.0027678625,0.000027183101,0.0014781127,0.050798878],"genre_scores_gemma":[0.9555606,0.0003693017,0.0003323044,0.0013768673,0.00073568395,0.00013737199,0.000041712963,0.00007917748,0.041366957],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987282,0.00003120454,0.00022293863,0.00029641364,0.00041792844,0.00030332676],"domain_scores_gemma":[0.9985261,0.000446346,0.00014187918,0.00071923557,0.00007964548,0.00008679592],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004512826,0.00024005145,0.00027322865,0.000040648305,0.00037950685,0.000103613376,0.00032080553,0.00013556625,0.0002724585],"category_scores_gemma":[0.00003613016,0.0000917736,0.0001687585,0.00011542546,0.00012931804,0.000027866714,0.00026236504,0.00066834537,0.00018771426],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.015112009,0.0014763207,0.01492558,0.004334017,0.049868032,0.0053363,0.030999852,0.040832724,0.0120597,0.20184611,0.38037312,0.24283624],"study_design_scores_gemma":[0.022894846,0.004243785,0.06912288,0.015908163,0.012318518,0.00081501686,0.07634908,0.113359675,0.107786655,0.24146333,0.32744935,0.008288695],"about_ca_topic_score_codex":0.00008617552,"about_ca_topic_score_gemma":0.000020737247,"teacher_disagreement_score":0.23454754,"about_ca_system_score_codex":0.000037968406,"about_ca_system_score_gemma":0.00026785777,"threshold_uncertainty_score":0.3742419},"labels":[],"label_agreement":null},{"id":"W4318713006","doi":"10.32920/21982895","title":"Lysosome remodelling and adaptation during phagocyte activation","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institutes of Health Research; Toronto Metropolitan University; Natural Sciences and Engineering Research Council of Canada","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canadian Institutes of Health Research; Government of Ontario","keywords":"TFEB; Lysosome; Autophagy; Cell biology; Phagocytosis; Biology; Phagocyte; Endocytosis; Cellular adaptation; Antigen presentation; Immune system; Cell; Immunology; T cell; Biochemistry; Gene","score_opus":0.08277131359421079,"score_gpt":0.3104084458096898,"score_spread":0.227637132215479,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318713006","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98065495,0.00031548727,0.016361926,0.00057168887,0.00018734798,0.0004304645,0.000004830708,0.0003761785,0.0010971456],"genre_scores_gemma":[0.98932076,0.0011749143,0.0029438436,0.00017101345,0.00033911166,0.000036770667,0.0001496455,0.000046865258,0.005817084],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9990573,0.000018179584,0.0002349784,0.00034999134,0.0002015641,0.00013796697],"domain_scores_gemma":[0.9994445,0.00003370994,0.00010711914,0.00026321926,0.00006103191,0.000090443114],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009745703,0.00016280697,0.00023780916,0.00015811383,0.000064343236,0.000028887613,0.0000419343,0.00018518104,0.00006987106],"category_scores_gemma":[0.000026982772,0.00014969167,0.000073812305,0.00007280753,0.000022545764,0.0000689212,0.00009629219,0.0002772372,0.000034631117],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01247783,0.0018901257,0.018644914,0.025067113,0.008890177,0.001518252,0.028940512,0.18268625,0.4678037,0.017291619,0.001976985,0.23281252],"study_design_scores_gemma":[0.0055451156,0.0001583265,0.120814435,0.0028804033,0.000638105,0.000044418804,0.0010634675,0.63894117,0.18489003,0.04366098,0.00034843638,0.00101514],"about_ca_topic_score_codex":0.00006252131,"about_ca_topic_score_gemma":0.0000020086595,"teacher_disagreement_score":0.45625487,"about_ca_system_score_codex":0.00006911592,"about_ca_system_score_gemma":0.00008663818,"threshold_uncertainty_score":0.61042494},"labels":[],"label_agreement":null},{"id":"W4319225950","doi":"10.1016/j.bbadis.2023.166647","title":"Autotaxin (ATX) inhibits autophagy leading to exaggerated disruption of intestinal epithelial barrier in colitis","year":2023,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"Autophagy; Colitis; Inflammatory bowel disease; Autotaxin; PI3K/AKT/mTOR pathway; Barrier function; Inflammation; Cancer research; Pharmacology; Chemistry; Immunology; Medicine; Signal transduction; Cell biology; Biology; Apoptosis; Internal medicine; Disease; Biochemistry; Receptor","score_opus":0.014433013564462993,"score_gpt":0.29739635471368764,"score_spread":0.28296334114922467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319225950","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99623996,0.00010087591,0.00008485393,0.0017201588,0.00011508706,0.00087954703,0.0005355628,0.00016819283,0.00015577034],"genre_scores_gemma":[0.9981439,0.000064363325,0.00031290928,0.00073395326,0.00008900612,0.00012145363,0.00031419293,0.00008872774,0.00013147038],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971651,0.00022932394,0.00075142976,0.00066817255,0.0006453764,0.0005406006],"domain_scores_gemma":[0.9980009,0.00011799474,0.0002730543,0.00069990614,0.00021701354,0.0006911363],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026041252,0.0004102831,0.0007277569,0.0007030419,0.000058164707,0.000027747406,0.00028128046,0.0001305133,0.000102688115],"category_scores_gemma":[0.0005954619,0.0004141216,0.000430037,0.001615957,0.00021263005,0.00014188337,0.00016874589,0.00022774322,0.00008295621],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022189063,0.0008342789,0.00014590053,0.00032943985,0.00016771223,0.0002415961,0.0004090261,0.000060337727,0.9937481,0.00068219705,0.00023888295,0.0009236048],"study_design_scores_gemma":[0.0016073944,0.00047175423,0.1249945,0.0008410061,0.00022019086,0.000003678447,0.000069605885,0.00067899923,0.8702645,0.00049712666,0.00002462134,0.00032662545],"about_ca_topic_score_codex":0.00006249644,"about_ca_topic_score_gemma":0.0000032212527,"teacher_disagreement_score":0.1248486,"about_ca_system_score_codex":0.00010158028,"about_ca_system_score_gemma":0.00052169414,"threshold_uncertainty_score":0.9998311},"labels":[],"label_agreement":null},{"id":"W4319320761","doi":"10.1038/s41420-023-01342-z","title":"Gemcitabine promotes autophagy and lysosomal function through ERK- and TFEB-dependent mechanisms","year":2023,"lang":"en","type":"article","venue":"Cell Death Discovery","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto; Cancer Research Society","keywords":"Autophagy; TFEB; MAPK/ERK pathway; Cell biology; ULK1; Function (biology); Gemcitabine; Lysosome; Biology; Chemistry; Neuroscience; Medicine; Kinase; Internal medicine; Protein kinase A; Cancer; AMPK; Biochemistry; Apoptosis; Enzyme","score_opus":0.016562382023755578,"score_gpt":0.25335159151946135,"score_spread":0.23678920949570578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319320761","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99090886,0.002637572,0.0024481593,0.00025501553,0.00032364082,0.00044922557,0.000028024317,0.00023920146,0.0027102875],"genre_scores_gemma":[0.98767155,0.001101117,0.0002727433,0.00062358385,0.00018958817,0.000046105808,0.000094959076,0.000044711513,0.009955636],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987338,0.00003278292,0.00020523084,0.00043883146,0.00026568322,0.0003236637],"domain_scores_gemma":[0.99943703,0.000053924847,0.00006171994,0.0002775703,0.000028284141,0.000141463],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012135989,0.00022414535,0.00028947656,0.00008779453,0.00014349203,0.00008220434,0.000053827836,0.00011770863,0.000114307804],"category_scores_gemma":[0.000019334007,0.00018462587,0.000076008735,0.0001331111,0.00006317284,0.0004060693,0.00009603562,0.00014393027,0.00008919143],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003184389,0.0018141771,0.026013382,0.0026117223,0.0011549745,0.0026974003,0.0031307107,0.000047701134,0.8273552,0.11033289,0.0032771765,0.018380273],"study_design_scores_gemma":[0.010060117,0.0025234567,0.47646543,0.0003323075,0.0010580644,0.00025802542,0.00094437297,0.001971176,0.37778744,0.12487612,0.0027629475,0.0009605566],"about_ca_topic_score_codex":0.00003008152,"about_ca_topic_score_gemma":0.0000018709319,"teacher_disagreement_score":0.45045206,"about_ca_system_score_codex":0.000029758647,"about_ca_system_score_gemma":0.00006345729,"threshold_uncertainty_score":0.7528825},"labels":[],"label_agreement":null},{"id":"W4319348255","doi":"10.1080/27694127.2023.2169518","title":"Venetoclax inhibits autophagy in chronic lymphocytic leukemia cells","year":2023,"lang":"en","type":"article","venue":"Autophagy Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; CancerCare Manitoba Foundation","keywords":"Venetoclax; Chronic lymphocytic leukemia; Autophagy; Cancer research; Leukemia; Medicine; Immunology; Biology; Apoptosis; Genetics","score_opus":0.01324678628455385,"score_gpt":0.2827682251706062,"score_spread":0.26952143888605234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319348255","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99020594,0.002510505,0.000013276427,0.0000609866,0.001035723,0.00082990155,0.0000060297198,0.0009623353,0.004375294],"genre_scores_gemma":[0.98692614,0.00046802338,0.00006760929,0.00068156025,0.00046664287,0.00017321995,0.00011927573,0.00010966427,0.01098785],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965063,0.00007141103,0.000992003,0.0008698245,0.0006273779,0.0009331395],"domain_scores_gemma":[0.99805987,0.00009316439,0.00029418862,0.0010944097,0.000081810584,0.00037657036],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005435631,0.00041793744,0.00072381843,0.0005421905,0.000113484304,0.000039000824,0.00015132297,0.00032039825,0.0007185099],"category_scores_gemma":[0.00009133037,0.00040586537,0.00028515005,0.0013848536,0.000132871,0.00018441626,0.00012653143,0.00035220428,0.0011284205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":true,"study_design_scores_codex":[0.000532783,0.00021175887,0.006662443,0.0011956565,0.0006736924,0.20793481,0.001788646,0.031423166,0.69444126,0.0008527714,0.027271384,0.027011652],"study_design_scores_gemma":[0.004494626,0.00049759366,0.107347235,0.0005556526,0.00016203099,0.0025390848,0.000060115675,0.029628418,0.82566404,0.002441059,0.025850456,0.000759703],"about_ca_topic_score_codex":0.0003692237,"about_ca_topic_score_gemma":0.000024858746,"teacher_disagreement_score":0.20539573,"about_ca_system_score_codex":0.01000374,"about_ca_system_score_gemma":0.009237484,"threshold_uncertainty_score":0.9998393},"labels":[],"label_agreement":null},{"id":"W4319432095","doi":"10.4049/jimmunol.206.supp.112.01","title":"Multiplexed proteomics of autophagy deficient macrophages reveals enhanced anti-microbial immunity via the oxidative stress response","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Autophagy; Innate immune system; Biology; Shigella flexneri; Cell biology; Oxidative stress; Immunity; ATG16L1; Immune system; Microbiology; Immunology; Biochemistry; Apoptosis; Gene","score_opus":0.012342958105745056,"score_gpt":0.27700415113961413,"score_spread":0.2646611930338691,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319432095","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891776,0.007736203,0.00091859704,0.0013496658,0.0003570111,0.00038078454,0.000029620145,0.000011057107,0.0000394497],"genre_scores_gemma":[0.9971142,0.0013334751,0.000800667,0.00034323888,0.00008347611,0.000005046857,0.0000058485393,0.000022342067,0.00029172402],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99671036,0.0018791251,0.00076491217,0.00011824251,0.00024119782,0.000286185],"domain_scores_gemma":[0.9968023,0.0008321604,0.0009048298,0.0006768241,0.00073261606,0.00005131426],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015295717,0.0001897597,0.0006083515,0.00010775568,0.00020729558,0.000011408707,0.00047978884,0.00013231437,0.00021741418],"category_scores_gemma":[0.0007305806,0.00010495924,0.00025479184,0.00029452497,0.0005730124,0.00006842581,0.00015700424,0.0007155404,0.000010936807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010843836,0.0005191051,0.000087524415,0.000026739142,0.000798405,0.00012777079,0.0031205788,0.00009717104,0.9832444,0.000050313756,0.000055951714,0.0010282053],"study_design_scores_gemma":[0.0028040302,0.00082191546,0.06436833,0.00016906548,0.00024244534,0.0010240971,0.0017472398,0.000020669087,0.92837316,0.0002619304,0.000082692364,0.000084438],"about_ca_topic_score_codex":0.00002557169,"about_ca_topic_score_gemma":0.00000282051,"teacher_disagreement_score":0.0642808,"about_ca_system_score_codex":0.000087733744,"about_ca_system_score_gemma":0.000489621,"threshold_uncertainty_score":0.42801136},"labels":[],"label_agreement":null},{"id":"W4319432374","doi":"10.4049/jimmunol.206.supp.17.30","title":"ATG16L1 deficiency exacerbates acute small intestinal epithelial damage.","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"ATG16L1; Autophagy; Paneth cell; Crypt; Apoptosis; Biology; Programmed cell death; Tumor necrosis factor alpha; Intestinal mucosa; Cancer research; Cytokine; Immune system; Immunology; Inflammatory bowel disease; Medicine; Internal medicine; Endocrinology; Disease; Small intestine","score_opus":0.01679907502361837,"score_gpt":0.27205147354349873,"score_spread":0.25525239851988035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319432374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98194665,0.012618127,0.0009185099,0.0028625051,0.00045727432,0.000059764512,0.0000028719153,0.000014544599,0.0011197544],"genre_scores_gemma":[0.99400836,0.0029444967,0.00084057444,0.00095095503,0.0002499839,0.0000010452477,0.0000032274256,0.000016946064,0.0009843808],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989544,0.00020746021,0.00038093244,0.00008271173,0.00014397001,0.000230507],"domain_scores_gemma":[0.99880016,0.00022028045,0.0002634262,0.00030317673,0.00034911628,0.00006386377],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003895702,0.000120456076,0.0003148437,0.00007775025,0.00009848568,0.000011020749,0.00025807976,0.00007394866,0.0005467622],"category_scores_gemma":[0.00021990345,0.00007206605,0.0001588166,0.00017803673,0.00022091677,0.00005460293,0.00007792641,0.00049538544,0.000060665083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024512697,0.00050327776,0.0016970504,0.000020061316,0.0010769278,0.0025904723,0.0014826385,0.000018711802,0.9733452,0.0013145207,0.0006295067,0.014870343],"study_design_scores_gemma":[0.007784219,0.004440962,0.236389,0.0003840695,0.0021753325,0.058153134,0.0024493998,0.000098958844,0.6706381,0.011141943,0.006019652,0.00032527407],"about_ca_topic_score_codex":0.00000893844,"about_ca_topic_score_gemma":0.0000021365624,"teacher_disagreement_score":0.30270717,"about_ca_system_score_codex":0.00004188048,"about_ca_system_score_gemma":0.00038412737,"threshold_uncertainty_score":0.59866625},"labels":[],"label_agreement":null},{"id":"W4321189307","doi":"10.1016/j.cellsig.2023.110631","title":"Parkin and mitochondrial signalling","year":2023,"lang":"en","type":"review","venue":"Cellular Signalling","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Gips-Schüle-Stiftung","keywords":"Parkin; PINK1; Mitophagy; Cell biology; Ubiquitin ligase; Mitochondrion; Ubiquitin; MFN1; Biology; mitochondrial fusion; Phosphorylation; Chemistry; Biochemistry; Autophagy; Mitochondrial DNA; Parkinson's disease; Medicine","score_opus":0.07968382260189825,"score_gpt":0.3383634446303267,"score_spread":0.2586796220284284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321189307","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00012424395,0.9955628,0.0020108777,0.000011794062,0.0005642055,0.001136617,0.000020553642,0.0002794246,0.00028950747],"genre_scores_gemma":[0.00006311141,0.99457085,0.00048405112,0.000063006446,0.0022803436,0.00011768682,0.00035496903,0.00023309309,0.0018329149],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974369,0.00013686024,0.0007909493,0.00074343866,0.00040154805,0.0004903078],"domain_scores_gemma":[0.99856365,0.00034700657,0.00030761398,0.0003735331,0.00005700405,0.00035120835],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028557685,0.0005916602,0.0020423755,0.00031129346,0.00015665629,0.00008108707,0.0002031608,0.0005321712,0.00023986657],"category_scores_gemma":[0.000060802708,0.000496022,0.00076735095,0.0003908832,0.00008812059,0.000049655337,0.00008570519,0.000697375,0.0004715919],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009040376,0.00016662173,0.0000023687353,0.055733338,0.0030028531,0.0032101485,0.00020445147,0.000011456306,0.0025221775,0.00038870514,0.0006205331,0.9340469],"study_design_scores_gemma":[0.00068126596,0.000114179646,2.4966664e-7,0.02924894,0.0042234412,0.000063107225,0.00001898133,0.00021955786,0.0004980898,0.00034763227,0.9640037,0.0005808489],"about_ca_topic_score_codex":0.0000060056345,"about_ca_topic_score_gemma":4.334259e-7,"teacher_disagreement_score":0.9633832,"about_ca_system_score_codex":0.00007267454,"about_ca_system_score_gemma":0.000351038,"threshold_uncertainty_score":0.9997491},"labels":[],"label_agreement":null},{"id":"W4321378035","doi":"10.1080/15548627.2023.2182595","title":"The role of programmed mitophagy in germline mitochondrial DNA quality control","year":2023,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Biology; Germline; Parkin; Mitochondrial DNA; Genetics; Autophagy; PINK1; Cell biology; Mitochondrion; Gene","score_opus":0.012200731730519696,"score_gpt":0.31461258045069895,"score_spread":0.30241184872017923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321378035","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99322903,0.0028862192,0.000022977707,0.0009171371,0.000582931,0.0009977296,0.000027566228,0.0002179116,0.0011184764],"genre_scores_gemma":[0.99755883,0.00018052217,0.00007536739,0.00029966322,0.0004174228,0.00020026533,0.000043159827,0.00003419564,0.0011905956],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99782336,0.00019545216,0.0006907975,0.00031722596,0.00044992034,0.0005232527],"domain_scores_gemma":[0.99838823,0.0005498128,0.00018881125,0.00060948887,0.00010741495,0.00015623636],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053546904,0.00020029528,0.0005126503,0.00014573969,0.000099307574,0.000020232661,0.00023638582,0.00014754546,0.00010172058],"category_scores_gemma":[0.0003764159,0.00014075445,0.0002529967,0.00066459645,0.000200257,0.00006137728,0.00004448658,0.00022467777,0.00013185543],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00668031,0.0018926036,0.03521511,0.00024907282,0.0009289954,0.00056149164,0.0018092074,0.000049378676,0.5937268,0.02181577,0.0025797638,0.33449146],"study_design_scores_gemma":[0.017123265,0.00065180665,0.66008735,0.000120187804,0.00012912517,0.000023102824,0.0006440093,0.002507725,0.25526398,0.014941886,0.04811842,0.00038914985],"about_ca_topic_score_codex":0.00016362262,"about_ca_topic_score_gemma":0.00004954676,"teacher_disagreement_score":0.6248722,"about_ca_system_score_codex":0.000048580947,"about_ca_system_score_gemma":0.00020059521,"threshold_uncertainty_score":0.57398},"labels":[],"label_agreement":null},{"id":"W4321598998","doi":"10.3390/ijms24054364","title":"1α,25(OH)2D3 Promotes the Autophagy of Porcine Ovarian Granulosa Cells as a Protective Mechanism against ROS through the BNIP3/PINK1 Pathway","year":2023,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Natural Science Foundation of China","keywords":"Autophagy; Reactive oxygen species; Cell biology; BECN1; Apoptosis; Biology; Mitochondrion; PINK1; Chemistry; Internal medicine; Mitophagy; Biochemistry; Medicine","score_opus":0.017836988961853976,"score_gpt":0.3016134620666826,"score_spread":0.2837764731048286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321598998","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9804017,0.0007484224,0.003923897,0.011816732,0.0008615755,0.00058528455,0.00001922474,0.000028034054,0.0016151397],"genre_scores_gemma":[0.99733317,0.000155433,0.0005081239,0.0015687131,0.00023091985,0.000019203593,0.000002981541,0.0000133604335,0.00016806816],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99739707,0.0001367474,0.00049425167,0.00020510166,0.0015491808,0.000217651],"domain_scores_gemma":[0.99845916,0.00013041761,0.00054848864,0.0002115057,0.00057324086,0.00007719886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001138519,0.0001579277,0.000247675,0.00018975421,0.00018207295,0.00007675885,0.0009352623,0.000057056608,0.000072969044],"category_scores_gemma":[0.00021065715,0.00007998676,0.0002847649,0.0005411694,0.00041789495,0.0001930025,0.00010957233,0.00027506484,0.000020889345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028529903,0.00032387392,0.00004295987,0.000021387792,0.0007321326,0.0016751359,0.005031503,0.00082132197,0.90401775,0.07985008,0.00011248247,0.0070860786],"study_design_scores_gemma":[0.0012309129,0.0008927127,0.0017893785,0.0002581174,0.00006884234,0.00040205024,0.0012382179,0.0016655046,0.8876522,0.1038158,0.0008713182,0.00011493979],"about_ca_topic_score_codex":0.000060024733,"about_ca_topic_score_gemma":0.0000021678095,"teacher_disagreement_score":0.023965722,"about_ca_system_score_codex":0.000049404567,"about_ca_system_score_gemma":0.00047903965,"threshold_uncertainty_score":0.32617655},"labels":[],"label_agreement":null},{"id":"W4322758302","doi":"10.1371/journal.pbio.3001977","title":"An AI-guided screen identifies probucol as an enhancer of mitophagy through modulation of lipid droplets","year":2023,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Toronto Western Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Parkin; Probucol; Mitochondrion; Biology; Cell biology; PINK1; Autophagy; Biochemistry; Cholesterol; Parkinson's disease; Internal medicine; Medicine; Apoptosis","score_opus":0.04479797946602129,"score_gpt":0.3750848778777087,"score_spread":0.33028689841168746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4322758302","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99820656,0.00019657056,0.00017816396,0.000256313,0.00014876845,0.00049382483,0.000039772138,0.00010774411,0.00037230842],"genre_scores_gemma":[0.9982803,0.00013943521,0.00024270795,0.00025462173,0.00030146656,0.00005048598,0.00039785568,0.000022153985,0.0003109675],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988909,0.000114816,0.0003709873,0.0002835231,0.0001393437,0.00020047439],"domain_scores_gemma":[0.99912447,0.00004387331,0.00015872154,0.0004218809,0.00018103649,0.00007000994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012017266,0.00012400914,0.0003771939,0.00012233353,0.00003659335,0.000003750658,0.0001339997,0.00016370359,0.00046736308],"category_scores_gemma":[0.00007077787,0.000103442886,0.000079390724,0.0002530212,0.00016586689,0.00014743234,0.000029883897,0.000079431746,0.000060183364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027671363,0.0004252783,0.010364224,0.000106560015,0.00019082126,0.000008665583,0.0008329357,0.000018850049,0.98466283,0.0016204007,0.0002993272,0.0011934013],"study_design_scores_gemma":[0.0010772665,0.0012347602,0.09545797,0.00006488773,0.000070916605,0.0000053225135,0.00012275812,0.0015492807,0.8903651,0.0097368155,0.00020519207,0.00010968126],"about_ca_topic_score_codex":0.00017804127,"about_ca_topic_score_gemma":0.000015273066,"teacher_disagreement_score":0.09429768,"about_ca_system_score_codex":0.000015074611,"about_ca_system_score_gemma":0.00008368635,"threshold_uncertainty_score":0.5117298},"labels":[],"label_agreement":null},{"id":"W4327980509","doi":"10.1080/27694127.2023.2188523","title":"Atg8 family proteins, LIR/AIM motifs and other interaction modes","year":2023,"lang":"en","type":"article","venue":"Autophagy Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Structural Genomics Consortium; H2020 European Research Council; Core Research for Evolutional Science and Technology; Wellcome Trust; Cancer Research UK; Biotechnology and Biological Sciences Research Council; Austrian Science Fund; Norges Forskningsråd; Genentech; National Natural Science Foundation of China; Ministry of Education, Culture, Sports, Science and Technology; Japan Agency for Medical Research and Development; McGill University; Deutsche Forschungsgemeinschaft; European Commission; Genome Canada; Ontario Genomics Institute; Francis Crick Institute; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Japan Society for the Promotion of Science; Directorate for Biological Sciences; Ontario Genomics; Medical Research Council; Bayer; Pfizer; Bristol-Myers Squibb","keywords":"ATG8; Protein–protein interaction; Computational biology; Docking (animal); Biology; Structural motif; Protein family; Autophagy; Cell biology; Chemistry; Genetics; Gene; Biochemistry","score_opus":0.0302821922477254,"score_gpt":0.3139536063813378,"score_spread":0.2836714141336124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4327980509","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885262,0.0010283187,0.00015099802,0.0003038574,0.00035311095,0.00060360646,0.0000048477596,0.00055680674,0.008472229],"genre_scores_gemma":[0.9912386,0.00013421553,0.00019050448,0.0011097954,0.00024168906,0.0001125723,0.000031472548,0.000055484175,0.006885647],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985698,0.0000338168,0.00038660437,0.0004337907,0.0002871501,0.00028886105],"domain_scores_gemma":[0.9990768,0.000033790715,0.00016822292,0.00047739115,0.000065333385,0.00017850653],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024295914,0.00019797985,0.00029951104,0.00016640371,0.00009987685,0.00003938005,0.000041011215,0.00012285853,0.00019533788],"category_scores_gemma":[0.000060220547,0.00016905738,0.000107677726,0.00026427748,0.0000763222,0.00016927734,0.00005033839,0.00017071085,0.00014458239],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012182359,0.0015780588,0.19682175,0.0010534336,0.0018961714,0.04319119,0.0043713977,0.00030737586,0.5519438,0.0047024298,0.03323591,0.15968025],"study_design_scores_gemma":[0.0023952115,0.00069291797,0.6336936,0.0005838825,0.00032403696,0.0042011454,0.00075724634,0.008422604,0.13050468,0.008750529,0.2088809,0.000793244],"about_ca_topic_score_codex":0.00014204906,"about_ca_topic_score_gemma":0.000003164869,"teacher_disagreement_score":0.43687186,"about_ca_system_score_codex":0.000043442953,"about_ca_system_score_gemma":0.00009528589,"threshold_uncertainty_score":0.689396},"labels":[],"label_agreement":null},{"id":"W4328048397","doi":"10.1038/s42255-023-00766-2","title":"PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing","year":2023,"lang":"en","type":"article","venue":"Nature Metabolism","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Guelph","funders":"National Institutes of Health; Bundesministerium für Bildung, Wissenschaft und Forschung; Science for Life Laboratory; Karolinska Institutet; Université de Strasbourg; Österreichische Forschungsförderungsgesellschaft; Österreichischen Akademie der Wissenschaften; Agence Nationale de la Recherche; Austrian Science Fund; European Commission; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Roy J. and Lucille A. Carver College of Medicine, University of Iowa; Spastic Paraplegia Foundation","keywords":"Failure to thrive; Muscle weakness; Ageing; Skeletal muscle; Biology; Muscular dystrophy; Sarcopenia; Cell biology; Internal medicine; Medicine; Endocrinology; Biochemistry","score_opus":0.014438932913956237,"score_gpt":0.33563678376408007,"score_spread":0.3211978508501238,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4328048397","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9283563,0.020981349,0.000032259704,0.04848383,0.0006645492,0.00038464757,0.00006230999,0.0003932632,0.0006414818],"genre_scores_gemma":[0.96289945,0.0008875424,0.00065173494,0.033991035,0.00076568394,0.00001673289,0.000024505225,0.00004339183,0.0007199248],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985758,0.00006709638,0.00021378396,0.00038502857,0.0003350846,0.00042318433],"domain_scores_gemma":[0.998787,0.00013569552,0.00003127467,0.0003573657,0.000081201484,0.0006074638],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025424935,0.00018140647,0.00042822756,0.00026676225,0.00015023981,0.000030306943,0.00009243432,0.0002598125,0.00024262768],"category_scores_gemma":[0.0005164634,0.00014887624,0.00010209726,0.0007289147,0.00005971935,0.0000673149,0.0000607326,0.00041853823,0.00017657295],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00080943323,0.0005418476,0.0007808187,0.0008261918,0.0006857812,0.0012339535,0.0077983113,0.000002699117,0.0887724,0.026282681,0.23448737,0.6377785],"study_design_scores_gemma":[0.0014503351,0.0001347548,0.36219066,0.0002487573,0.0001802573,0.000025413157,0.00037680982,0.00026201518,0.019743146,0.0016409559,0.6134088,0.0003380536],"about_ca_topic_score_codex":0.00002391971,"about_ca_topic_score_gemma":0.0000018352782,"teacher_disagreement_score":0.63744044,"about_ca_system_score_codex":0.000020667849,"about_ca_system_score_gemma":0.000107383625,"threshold_uncertainty_score":0.6070997},"labels":[],"label_agreement":null},{"id":"W4360600077","doi":"10.1080/22221751.2023.2195020","title":"Berbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade","year":2023,"lang":"en","type":"article","venue":"Emerging Microbes & Infections","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Society of Intestinal Research; Simon Fraser University; University of British Columbia; Institute of Infection and Immunity","funders":"Center for the Management of Systemic Risk, Columbia University; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Universiteit van Amsterdam; ZonMw; Australian Prime Ministers Centre; Amsterdam University Medical Centers","keywords":"Autophagy; Viral entry; Blockade; Biology; Virus; Immunology; Virology; Viral replication; Medicine; Receptor; Genetics","score_opus":0.022166586826108406,"score_gpt":0.31906182467004707,"score_spread":0.2968952378439387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4360600077","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99023,0.00041095747,0.003211463,0.0007919578,0.0012004519,0.00045395287,0.000021373182,0.0016317377,0.0020480645],"genre_scores_gemma":[0.99517584,0.00038399966,0.0002077294,0.00045845858,0.00065920997,0.00014896996,0.00017753418,0.00008293587,0.0027053505],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981814,0.00007730462,0.00044555255,0.00048508626,0.00025500165,0.0005556706],"domain_scores_gemma":[0.9989823,0.00011474045,0.0001272217,0.0004687067,0.00017413558,0.00013289947],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020783822,0.00033543253,0.00036619845,0.00064046966,0.00046219068,0.00005871045,0.000106077016,0.00014817751,0.00053526287],"category_scores_gemma":[0.00012656121,0.00033549618,0.00028542828,0.0011945289,0.00011881213,0.00020850413,0.00011631316,0.00043573606,0.0011185565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058729885,0.0007524308,0.014170643,0.00013399955,0.0004438375,0.00015691845,0.00044120543,0.0002797874,0.96711755,0.00012339189,0.011011505,0.0053100055],"study_design_scores_gemma":[0.0017914333,0.00046848741,0.055100955,0.00024179067,0.0004972075,0.0010206575,0.000050113744,0.0013850423,0.87413836,0.0006097563,0.06424821,0.0004479845],"about_ca_topic_score_codex":0.0010464914,"about_ca_topic_score_gemma":0.00020852246,"teacher_disagreement_score":0.092979185,"about_ca_system_score_codex":0.00015021132,"about_ca_system_score_gemma":0.00012437059,"threshold_uncertainty_score":0.9999097},"labels":[],"label_agreement":null},{"id":"W4360610031","doi":"10.12688/f1000research.132628.1","title":"The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence","year":2023,"lang":"en","type":"preprint","venue":"F1000Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"ALS Society of Canada; Canadian Institutes of Health Research; Mitacs; Ontario Genomics; Genome Canada; Motor Neurone Disease Association; ALS Association","keywords":"Western blot; Immunofluorescence; Immunoprecipitation; Antibody; Identification (biology); Biology; Immunology; Biochemistry; Botany","score_opus":0.0927901287158647,"score_gpt":0.40042822705184594,"score_spread":0.3076380983359812,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4360610031","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906424,0.0031451671,0.0014143889,0.0007050971,0.000340374,0.0034369184,0.0002647342,0.000047596237,0.0000033167285],"genre_scores_gemma":[0.9864325,0.007625001,0.00095695775,0.000016410208,0.00013134781,0.0014940866,0.0005188356,0.00006732504,0.0027575232],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981531,0.00009205399,0.00064151303,0.00038737088,0.0003912295,0.00033473736],"domain_scores_gemma":[0.99708796,0.0014978098,0.00022427249,0.00061028433,0.00052765105,0.00005204513],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017237256,0.00016914177,0.00035212134,0.0003062977,0.0001960584,0.00013084427,0.0002818649,0.00017824411,0.0000024363567],"category_scores_gemma":[0.0008301259,0.00013234276,0.00010821874,0.00015258678,0.0002511529,0.0001384207,0.0002614298,0.00033148803,0.0000045030315],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018035442,0.0010161742,0.24233365,0.017836332,0.0021654114,0.00003920543,0.01237125,0.00067011855,0.55658984,0.007865606,0.0029805738,0.13809639],"study_design_scores_gemma":[0.0029668333,0.00047399386,0.8428548,0.0016924639,0.00014153431,0.0000042331126,0.0006757239,0.011299991,0.120790735,0.018124148,0.0006943687,0.00028115415],"about_ca_topic_score_codex":0.0006167559,"about_ca_topic_score_gemma":0.00010367207,"teacher_disagreement_score":0.60052115,"about_ca_system_score_codex":0.000098111464,"about_ca_system_score_gemma":0.0002706092,"threshold_uncertainty_score":0.5396781},"labels":[],"label_agreement":null},{"id":"W4361219031","doi":"10.1016/j.jnutbio.2023.109337","title":"Glycophagy mediated glucose-induced changes of hepatic glycogen metabolism via OGT1-AKT1-FOXO1Ser238 pathway","year":2023,"lang":"en","type":"article","venue":"The Journal of Nutritional Biochemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Key Research and Development Program of China","keywords":"FOXO1; Glycogen synthase; Glycogen; AKT1; Phosphorylation; Protein kinase B; Biology; Carbohydrate metabolism; AKT2; Chemistry; Biochemistry; Cell biology; Endocrinology; Internal medicine","score_opus":0.018035211962215362,"score_gpt":0.2691536357348041,"score_spread":0.25111842377258875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4361219031","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98627543,0.010372658,0.000019796662,0.0026312328,0.00019562898,0.00017075897,0.00015085291,0.000039018436,0.00014459211],"genre_scores_gemma":[0.99501526,0.0031334963,0.00009100735,0.0005144563,0.0009532513,0.000010378774,0.000143192,0.000030096202,0.00010886696],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981638,0.000090553076,0.00055435725,0.00013725094,0.00078392343,0.00027010072],"domain_scores_gemma":[0.9981806,0.0003877214,0.00048499918,0.0002628693,0.00046052257,0.00022326304],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057788723,0.00020962239,0.00050468725,0.00016666715,0.000087159446,0.0000080087975,0.00028576527,0.0001582145,0.00026507923],"category_scores_gemma":[0.00023302964,0.00014523811,0.00027964448,0.00058005657,0.00013183507,0.00005370394,0.00004821938,0.00032884977,0.000037914233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012421124,0.00037552213,0.000074025535,0.00023509654,0.0004773554,0.00017859737,0.000110848254,0.0000015936764,0.99489486,0.00001760198,0.0013774738,0.0010148983],"study_design_scores_gemma":[0.0031424554,0.0002968094,0.004197013,0.00036241274,0.00032119828,0.0006496798,0.00019142413,0.000062189116,0.9883198,0.0016034615,0.00072088063,0.00013268969],"about_ca_topic_score_codex":0.000010770868,"about_ca_topic_score_gemma":7.8721445e-7,"teacher_disagreement_score":0.008739794,"about_ca_system_score_codex":0.000060473463,"about_ca_system_score_gemma":0.00030186362,"threshold_uncertainty_score":0.5922638},"labels":[],"label_agreement":null},{"id":"W4361287162","doi":"10.1098/rspb.2023.0407","title":"Transcriptional profiling of the response to starvation and fattening reveals differential regulation of autophagy genes in mammals","year":2023,"lang":"en","type":"article","venue":"Proceedings of the Royal Society B Biological Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Azrieli Foundation","keywords":"Autophagy; Biology; Starvation; Gene; Cell biology; Transcription factor; Autophagosome; ULK1; Cell; Genetics; Endocrinology; Apoptosis; Kinase; Protein kinase A","score_opus":0.03756972789945378,"score_gpt":0.2876675018226562,"score_spread":0.2500977739232024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4361287162","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981441,0.00008832353,0.000017322614,0.0013204598,0.00004085779,0.00033632203,0.000008200681,0.000012903722,0.00003152668],"genre_scores_gemma":[0.9990498,0.000025914214,0.0007322451,0.00007394586,0.000026008938,0.000012263214,8.9277484e-7,0.0000021499354,0.00007682064],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991157,0.000026769956,0.00026253107,0.00016799636,0.00029698244,0.00012998842],"domain_scores_gemma":[0.99958897,0.000096768206,0.00015581016,0.00003868564,0.00009135164,0.000028426964],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010174377,0.00006723185,0.00017434025,0.000030063984,0.00010934538,0.000007296526,0.00017120651,0.00006967939,0.000017066313],"category_scores_gemma":[0.00023657877,0.000032083546,0.00012394197,0.00059329264,0.00046084088,0.000040703828,0.00007827306,0.00006116409,1.9152071e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020039183,0.000024234663,0.25205147,0.000039598333,0.000008576464,1.7105872e-8,0.00047781132,0.00003640151,0.74577355,0.0010229464,0.000017675038,0.0003473318],"study_design_scores_gemma":[0.00020667806,0.00015476653,0.80722773,0.00009893661,0.000009866605,3.2127244e-7,0.00051797385,0.0020896285,0.18736205,0.002297517,0.0000035898433,0.00003092349],"about_ca_topic_score_codex":0.000010919339,"about_ca_topic_score_gemma":1.5510419e-7,"teacher_disagreement_score":0.5584115,"about_ca_system_score_codex":0.000016708489,"about_ca_system_score_gemma":0.00003193085,"threshold_uncertainty_score":0.16979875},"labels":[],"label_agreement":null},{"id":"W4361958883","doi":"10.1158/1078-0432.c.6518056.v1","title":"Data from Measurements of Tumor Cell Autophagy Predict Invasiveness, Resistance to Chemotherapy, and Survival in Melanoma","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"National Institutes of Health; National Cancer Institute; University of Pennsylvania","keywords":"Autophagy; ATG5; Melanoma; Cancer research; Small hairpin RNA; Temozolomide; Programmed cell death; Apoptosis; Medicine; Chemistry; Glioma; Gene knockdown","score_opus":0.10145778630805727,"score_gpt":0.3216017307181594,"score_spread":0.22014394441010213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4361958883","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98952,0.0028135406,0.00024341508,0.000633354,0.00050612714,0.0012945806,0.0017836381,0.00013032417,0.0030750243],"genre_scores_gemma":[0.9917597,0.0005891553,0.002437733,0.0006656146,0.00022377691,0.00008282758,0.001370668,0.00010095051,0.002769584],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99727815,0.00012016064,0.0006326621,0.0010192306,0.00066108553,0.00028868802],"domain_scores_gemma":[0.99739385,0.00014593825,0.00022165445,0.0019043306,0.000110234105,0.00022397314],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00060514716,0.00035619436,0.0009237034,0.0002088581,0.00002479225,0.000024277986,0.0006897371,0.00020358278,0.00038328613],"category_scores_gemma":[0.00012723889,0.00032708157,0.00007866272,0.00020841548,0.00007246337,0.00006321279,0.0009524776,0.0003316279,0.000033635857],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009065405,0.0026799305,0.86178493,0.005968277,0.002548493,0.0013011592,0.0018326516,0.000102396174,0.081809424,0.000092777525,0.030835144,0.0019794032],"study_design_scores_gemma":[0.005206836,0.00014016712,0.8609384,0.0018532604,0.00021782304,0.0000012117018,0.0001511662,0.0002150237,0.12758371,0.0019008592,0.0013361685,0.0004554197],"about_ca_topic_score_codex":0.0012447588,"about_ca_topic_score_gemma":0.0017180681,"teacher_disagreement_score":0.045774285,"about_ca_system_score_codex":0.0000894918,"about_ca_system_score_gemma":0.0005382123,"threshold_uncertainty_score":0.9999181},"labels":[],"label_agreement":null},{"id":"W4362592757","doi":"10.1158/1538-7445.am2023-3956","title":"Abstract 3956: Identifying PIKfyve as potential target in clear cell renal cell carcinoma with a loss of the von Hippel-Lindau tumor suppressor gene","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Moncton","funders":"","keywords":"Cancer research; Clear cell renal cell carcinoma; Gene knockdown; Biology; Renal cell carcinoma; Von Hippel–Lindau disease; Cancer; Tumor suppressor gene; Suppressor; Carcinogenesis; Clear cell; Programmed cell death; Cancer cell; Pathology; Gene; Medicine; Genetics; Disease; Apoptosis","score_opus":0.0428851298971027,"score_gpt":0.36062790438122944,"score_spread":0.31774277448412674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362592757","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958825,0.0015106491,0.000005250361,0.0005454141,0.00015404314,0.00077570614,0.00008099423,0.000031695196,0.0010137423],"genre_scores_gemma":[0.9967459,0.00017633385,0.000027317263,0.00009765595,0.0003040537,0.00012289509,0.000027800303,0.000063037514,0.0024350318],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971069,0.00016797236,0.00032470777,0.00043966508,0.0012264793,0.00073424954],"domain_scores_gemma":[0.9987463,0.00008951722,0.000103888364,0.0005928789,0.00025471405,0.00021275076],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007486765,0.00017572133,0.00031131718,0.0003166444,0.00016488713,0.000037319194,0.00041776648,0.000095484764,0.0011006092],"category_scores_gemma":[0.00004003219,0.00012162349,0.00013430878,0.0009743615,0.00031367323,0.00009505795,0.00018429497,0.00080470083,0.00014940166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0042503313,0.00037126575,0.029361254,0.0008060941,0.000067098925,0.0026944173,0.0017875065,0.00045756417,0.95727324,0.000020241225,0.0026904126,0.00022059595],"study_design_scores_gemma":[0.0027455795,0.0002862215,0.2243781,0.00020603208,0.000027508408,0.000015182046,0.00059386657,0.00021291939,0.77082664,0.00022781073,0.00036214385,0.00011800203],"about_ca_topic_score_codex":0.0017251469,"about_ca_topic_score_gemma":0.00006944914,"teacher_disagreement_score":0.19501683,"about_ca_system_score_codex":0.00019404152,"about_ca_system_score_gemma":0.0010278855,"threshold_uncertainty_score":0.99981254},"labels":[],"label_agreement":null},{"id":"W4362596199","doi":"10.1158/1538-7445.am2023-3617","title":"Abstract 3617: Investigating a role for PIKfyve in cell migration and invasion of clear cell renal cell carcinoma","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Moncton","funders":"","keywords":"Biology; Cancer research; Clear cell renal cell carcinoma; Gene knockdown; Small hairpin RNA; Cell biology; Programmed cell death; Angiogenesis; Metastasis; Cancer; Renal cell carcinoma; Pathology; Cell culture; Medicine; Apoptosis; Biochemistry; Genetics","score_opus":0.09187318543754602,"score_gpt":0.3861822095921061,"score_spread":0.29430902415456006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362596199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99576306,0.0020484582,0.0000024449394,0.00036399567,0.000027895469,0.0006588252,0.00002744164,0.000019128327,0.0010887367],"genre_scores_gemma":[0.998276,0.0004571585,0.000096079806,0.00006573208,0.0001208241,0.00016074766,0.00004092218,0.000027174206,0.00075534265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987181,0.000060813385,0.00023134476,0.00026638128,0.0003605871,0.00036278553],"domain_scores_gemma":[0.99921453,0.00021204518,0.000060259863,0.00019274584,0.00014963766,0.00017079331],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074102695,0.0000904843,0.00018252396,0.0002837888,0.000082398496,0.000015692165,0.00008557656,0.00009037737,0.000071551454],"category_scores_gemma":[0.00007181115,0.00008273972,0.000046545065,0.00047124756,0.00011153908,0.0000698191,0.00005089419,0.00028097344,0.000016040727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040872634,0.000090752146,0.032483663,0.0008811132,0.0000048163615,0.00002050643,0.001961706,0.00003975168,0.9606397,0.000012144902,0.0015912006,0.0018659094],"study_design_scores_gemma":[0.0020020036,0.00040123885,0.14401025,0.00017149729,0.000009991877,4.878948e-7,0.00116276,0.00142743,0.8494402,0.0005684488,0.00073066546,0.00007499916],"about_ca_topic_score_codex":0.0014508743,"about_ca_topic_score_gemma":0.000214999,"teacher_disagreement_score":0.11152658,"about_ca_system_score_codex":0.00009331485,"about_ca_system_score_gemma":0.00043310938,"threshold_uncertainty_score":0.33740282},"labels":[],"label_agreement":null},{"id":"W4362691876","doi":"10.1371/journal.pone.0284026","title":"Comprehensive proteomic analysis of autophagosomes derived from Leishmania-infected macrophages","year":2023,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Genome British Columbia","keywords":"Autophagy; Leishmania donovani; Proteome; Biology; Leishmania; Cell biology; Intracellular parasite; Amastigote; Intracellular; Autophagosome; Phagosome; Cell culture; Biochemistry; Leishmaniasis; Immunology; Visceral leishmaniasis; Apoptosis; Parasite hosting; Genetics","score_opus":0.0459505858626085,"score_gpt":0.27443971414777174,"score_spread":0.22848912828516324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362691876","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977327,0.0006616008,0.000017760827,0.00023867318,0.000028292228,0.0006020612,0.0001890247,0.00036385152,0.0001660175],"genre_scores_gemma":[0.9975174,0.0003802913,0.00059553783,0.000240246,0.00009298304,0.000071934606,0.0005871311,0.00003366003,0.0004807813],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99863654,0.00006395668,0.0003239718,0.00031400553,0.0004136936,0.00024781344],"domain_scores_gemma":[0.99890304,0.00014154932,0.00014237703,0.00047680121,0.00020296784,0.00013329231],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000043119282,0.00018066888,0.0008284666,0.0004679303,0.00005682505,0.000012056105,0.000120219906,0.00009733753,0.0012940682],"category_scores_gemma":[0.00005990891,0.00016462183,0.00025422408,0.0014523173,0.00009646045,0.00005589983,0.000057526417,0.0001322698,0.0002430282],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022813826,0.0010921628,0.05586127,0.00014571568,0.015561728,0.00013479812,0.00040360144,0.000025047459,0.9261304,0.000016551525,0.00007655092,0.00032403445],"study_design_scores_gemma":[0.00091639406,0.0001045895,0.5511046,0.000082508814,0.003595132,2.6326734e-7,0.00004187402,0.002327155,0.4416328,0.00009987304,0.0000064353576,0.00008839735],"about_ca_topic_score_codex":0.00013906842,"about_ca_topic_score_gemma":0.000005101681,"teacher_disagreement_score":0.4952433,"about_ca_system_score_codex":0.000034876066,"about_ca_system_score_gemma":0.000067141766,"threshold_uncertainty_score":0.9996189},"labels":[],"label_agreement":null},{"id":"W4362700442","doi":"10.1038/s41419-022-05484-3","title":"Autophagy deficiency exacerbates iron overload induced reactive oxygen species production and apoptotic cell death in skeletal muscle cells","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research; York University; International Development Research Centre; Government of Canada","keywords":"Autophagy; Reactive oxygen species; Cell biology; Apoptosis; Programmed cell death; Skeletal muscle; Oxygen; Mitochondrion; Myocyte; Biology; Chemistry; Biochemistry; Endocrinology","score_opus":0.01858606746596604,"score_gpt":0.24941774680130543,"score_spread":0.23083167933533938,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362700442","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99295527,0.0034445669,0.0000042774027,0.00015996849,0.00020826099,0.00067131035,0.000033812154,0.00014051262,0.002381996],"genre_scores_gemma":[0.99518496,0.0014337408,0.000041387433,0.00018610015,0.00016911162,0.00005058292,0.0001048139,0.000036089423,0.0027931964],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99835247,0.000058692345,0.00025110738,0.00062732736,0.00026400347,0.00044640916],"domain_scores_gemma":[0.9988265,0.00005849126,0.00008097914,0.00033177587,0.00004364176,0.00065859046],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014095758,0.00028006115,0.00029321888,0.00023879803,0.0001579226,0.00004458695,0.00007026601,0.000096009324,0.00007149318],"category_scores_gemma":[0.0000903525,0.0002514001,0.00008468523,0.00032674952,0.000080496204,0.00019059354,0.000067761626,0.0001811651,0.000076144024],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011715973,0.0029117805,0.06301018,0.0023090085,0.000051437186,0.0015023329,0.0035676982,0.00011247712,0.91764355,0.0006233756,0.0015919366,0.0055046263],"study_design_scores_gemma":[0.0019202341,0.00027988723,0.93730974,0.000096958276,0.00019630036,0.000004356937,0.0006280229,0.00061975804,0.05713565,0.0010312897,0.0004316569,0.00034614257],"about_ca_topic_score_codex":0.000051510462,"about_ca_topic_score_gemma":0.000002746438,"teacher_disagreement_score":0.8742996,"about_ca_system_score_codex":0.00006983606,"about_ca_system_score_gemma":0.000189013,"threshold_uncertainty_score":0.9999938},"labels":[],"label_agreement":null},{"id":"W4363677815","doi":"10.3390/cancers15082195","title":"Regulation of Autophagy via Carbohydrate and Lipid Metabolism in Cancer","year":2023,"lang":"en","type":"review","venue":"Cancers","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research Institute in Oncology and Hematology; University of Alberta; Children's Hospital Research Institute of Manitoba; CancerCare Manitoba; Health Sciences Centre; St. Boniface Hospital; University of Manitoba","funders":"Max Rady College of Medicine, University of Manitoba; CancerCare Manitoba Foundation","keywords":"Autophagy; Organelle; Cell biology; Lipid metabolism; Metabolic pathway; Cancer cell; Biochemistry; Carcinogenesis; Cell metabolism; Metabolism; Biology; Glycolysis; Cell; Carbohydrate metabolism; Chemistry; Lipid droplet; Cancer; Apoptosis","score_opus":0.049807296235796245,"score_gpt":0.3663446238384224,"score_spread":0.3165373276026262,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4363677815","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012417221,0.99720955,0.000004933574,0.000016869086,0.0005580377,0.0006688399,0.00006175309,0.00004184442,0.00019643894],"genre_scores_gemma":[0.000580183,0.9977107,0.000015115416,0.000060076953,0.00039218256,0.00026439613,0.000092927694,0.00006186083,0.0008225307],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988353,0.0000573579,0.00045096027,0.0002985229,0.00016446777,0.0001933743],"domain_scores_gemma":[0.9992837,0.00004621463,0.0002594703,0.00026938735,0.000039236584,0.00010204649],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000115757364,0.00023756054,0.001406317,0.0002890098,0.00001760853,0.000004760288,0.00007294067,0.00020831513,0.00013763124],"category_scores_gemma":[0.00001675496,0.00019629944,0.00019309463,0.0005480436,0.000083411374,0.000038295086,0.000024851843,0.00019410446,0.000008921777],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003506827,0.000010473932,0.000009521174,0.017226528,0.0004645338,0.00002726072,0.0001741895,0.00003862789,0.000109796325,0.00014580548,0.00022584065,0.98153234],"study_design_scores_gemma":[0.0009116338,0.000043349268,0.0015833742,0.018063154,0.0019262555,0.00000691662,0.000013314514,0.00030847942,0.00013242949,0.0002094299,0.9765051,0.00029653832],"about_ca_topic_score_codex":0.0010215177,"about_ca_topic_score_gemma":0.00008192219,"teacher_disagreement_score":0.9812358,"about_ca_system_score_codex":0.0006100087,"about_ca_system_score_gemma":0.0014016331,"threshold_uncertainty_score":0.8004859},"labels":[],"label_agreement":null},{"id":"W4365147844","doi":"10.3390/cells12081132","title":"Membrane Curvature: The Inseparable Companion of Autophagy","year":2023,"lang":"en","type":"review","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Wuhan Science and Technology Project; Hubei University; Hubei University of Technology; National Natural Science Foundation of China","keywords":"Membrane curvature; Cell biology; Elasticity of cell membranes; ATG8; Autophagosome; Autophagy; Lipid bilayer; Membrane; Chemistry; Membrane protein; Biology; Integral membrane protein; Biophysics; Biochemistry","score_opus":0.0888710913210139,"score_gpt":0.3795407143901347,"score_spread":0.2906696230691208,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4365147844","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000056735782,0.9953486,0.000003797323,0.000030896834,0.00064658164,0.000970411,0.00006202208,0.00010105,0.0027799122],"genre_scores_gemma":[0.00004994749,0.9888028,0.000019484867,0.00016333534,0.0003282097,0.000055614404,0.00017217293,0.00007966516,0.010328755],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998554,0.00012769346,0.0005198544,0.00026960974,0.00029101208,0.00023783304],"domain_scores_gemma":[0.99851483,0.00026960243,0.00031898852,0.00074568327,0.000051544528,0.00009932379],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002562632,0.00030070168,0.0015556109,0.000109398796,0.000055491357,0.000011202859,0.00029766653,0.00028250727,0.00041827373],"category_scores_gemma":[0.00002256565,0.0001694467,0.0006451894,0.0005065277,0.00010938793,0.00002237408,0.00005943786,0.00043990242,0.0009149289],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000067149405,0.0005627231,0.0000015068143,0.12095244,0.0031085243,0.00033726962,0.00034304603,0.0000063700427,0.00033869085,0.0017436855,0.064724326,0.80781424],"study_design_scores_gemma":[0.0002966929,0.000052972864,0.000007831,0.007962591,0.0015458029,0.000022373259,0.0000078114745,0.000010426722,0.001239741,0.000064119035,0.9886481,0.00014150202],"about_ca_topic_score_codex":0.00001596303,"about_ca_topic_score_gemma":5.942822e-7,"teacher_disagreement_score":0.9239238,"about_ca_system_score_codex":0.000041348245,"about_ca_system_score_gemma":0.00034549946,"threshold_uncertainty_score":0.99986297},"labels":[],"label_agreement":null},{"id":"W4365448823","doi":"10.3390/cells12081143","title":"USP8 Down-Regulation Promotes Parkin-Independent Mitophagy in the Drosophila Brain and in Human Neurons","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council Canada; Università degli Studi di Milano; Medical Research Council; Michael J. Fox Foundation for Parkinson's Research","keywords":"Mitophagy; Parkin; PINK1; Cell biology; Autophagy; Mitochondrion; Ubiquitin; Ubiquitin ligase; Biology; Neurodegeneration; Deubiquitinating enzyme; Autophagosome; Genetics; Parkinson's disease; Gene","score_opus":0.019247941368137112,"score_gpt":0.28771338146243775,"score_spread":0.2684654400943006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4365448823","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99566513,0.00023719219,0.0000017925933,0.0026537003,0.00007805145,0.00049389264,0.0000037173033,0.00003963356,0.0008268587],"genre_scores_gemma":[0.99811697,0.00004116335,0.0000063636453,0.0008373292,0.00011471988,0.00003468483,0.000030936877,0.000014678645,0.0008031693],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991395,0.0000954314,0.00017905705,0.0002093542,0.00018307126,0.00019360245],"domain_scores_gemma":[0.9995598,0.00011260152,0.000035364363,0.00023175591,0.000009905264,0.000050558963],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028486177,0.00010165569,0.00014498812,0.00014082988,0.00005262772,0.000021606229,0.00008142067,0.0000645942,0.00007967483],"category_scores_gemma":[0.000020798701,0.00007509247,0.000037281818,0.0002954695,0.00005187669,0.000045124707,0.000026660788,0.00015115504,0.000044771867],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017338297,0.00062562013,0.052135326,0.00017148806,0.00004474267,0.0011181344,0.0054829186,0.0001222216,0.92791104,0.0012470441,0.00527207,0.0056959935],"study_design_scores_gemma":[0.0015194231,0.00010786336,0.9528766,0.000055777655,0.000014617852,0.0000115548955,0.00013065283,0.00046471908,0.038980726,0.004351713,0.0013934865,0.00009286543],"about_ca_topic_score_codex":0.000031488285,"about_ca_topic_score_gemma":0.00003960073,"teacher_disagreement_score":0.9007413,"about_ca_system_score_codex":0.000019151119,"about_ca_system_score_gemma":0.000024500494,"threshold_uncertainty_score":0.3062182},"labels":[],"label_agreement":null},{"id":"W4366449373","doi":"10.1126/sciadv.adf9284","title":"Autophagy supports mitochondrial metabolism through the regulation of iron homeostasis in pancreatic cancer","year":2023,"lang":"en","type":"article","venue":"Science Advances","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Stand Up To Cancer; York University; Howard Hughes Medical Institute","keywords":"Autophagy; Cell biology; Pancreatic cancer; Biology; Pinocytosis; Mitochondrion; Cancer research; Homeostasis; Mitophagy; Metabolism; Cancer; Biochemistry; Endocytosis; Cell; Apoptosis; Genetics","score_opus":0.016446640923906124,"score_gpt":0.33189743056356996,"score_spread":0.31545078963966383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366449373","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99036306,0.0069766855,0.000029039245,0.000993864,0.0006850245,0.000336508,0.0000113015485,0.000047370973,0.00055712735],"genre_scores_gemma":[0.9970988,0.0015250244,0.0004221719,0.0001950839,0.00015904749,0.00006525683,0.0000066836,0.000008015338,0.0005199424],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986591,0.000029586674,0.00023650221,0.00026488423,0.0005276113,0.00028234147],"domain_scores_gemma":[0.99939036,0.00007235657,0.00011418189,0.00030361253,0.00006897351,0.000050538372],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024822276,0.00009530466,0.00022098339,0.00014553826,0.00012330699,0.000013340854,0.00019023621,0.000027856579,0.00018721497],"category_scores_gemma":[0.00011241742,0.00005976258,0.000054941866,0.0017722577,0.00061206275,0.00054543413,0.00003393324,0.00007018961,0.000015548727],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065119145,0.00026944204,0.02250351,0.00026189204,0.000059880316,0.000060288014,0.010596319,0.004628857,0.76668626,0.006215491,0.000987255,0.18707964],"study_design_scores_gemma":[0.0010865295,0.000082803854,0.71447486,0.00013492181,0.00007324751,0.000005660947,0.0010445674,0.0003714988,0.26279193,0.01168308,0.008118462,0.0001324115],"about_ca_topic_score_codex":0.00015527499,"about_ca_topic_score_gemma":0.000038273934,"teacher_disagreement_score":0.69197136,"about_ca_system_score_codex":0.000042252825,"about_ca_system_score_gemma":0.00028711473,"threshold_uncertainty_score":0.24370474},"labels":[],"label_agreement":null},{"id":"W4366742757","doi":"10.1016/j.celrep.2023.112372","title":"NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency","year":2023,"lang":"en","type":"article","venue":"Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Institute of Mental Health; Uehara Memorial Foundation; Wellcome Trust; Cancer Research UK; Biotechnology and Biological Sciences Research Council; National Institute for Health and Care Research; National Institute on Aging; Surgical Reconstruction and Microbiology Research Centre; LEO Fondet; University of Balamand; Fundação de Amparo à Pesquisa do Estado de São Paulo; National Institutes of Health; University of Birmingham; Japan Society for the Promotion of Science London; Japan Society for the Promotion of Science; Medical Research Council; International Seafood Sustainability Foundation; Emerald Foundation; Department of Science and Technology, Ministry of Science and Technology, India; LifeArc; Eunice Kennedy Shriver National Institute of Child Health and Human Development; UK-India Education and Research Initiative; National Institute of Neurological Disorders and Stroke; International Pediatric Research Foundation","keywords":"Cytotoxicity; Autophagy; NAD+ kinase; Cell biology; Chemistry; Biology; Biochemistry; Apoptosis; Enzyme; In vitro","score_opus":0.014490835102772359,"score_gpt":0.26862082947699284,"score_spread":0.25412999437422046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366742757","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907949,0.00022582263,0.000022166496,0.00009830525,0.00012447535,0.00034332176,0.0000014508972,0.00025774332,0.008131843],"genre_scores_gemma":[0.99816984,0.000054493477,0.000032612337,0.00021425057,0.00007023004,0.00004600907,0.000069262394,0.000030054143,0.0013132239],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987026,0.000028382448,0.00031449462,0.00034707726,0.00030684608,0.00030059193],"domain_scores_gemma":[0.9992695,0.00003271235,0.00012637275,0.00039152388,0.00003857029,0.0001413076],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022040708,0.00013863647,0.00021837039,0.00018737401,0.00008761103,0.000012310252,0.00004739396,0.00007227154,0.00016874763],"category_scores_gemma":[0.000046937363,0.000111978065,0.000059022284,0.00049146084,0.0000658805,0.000057067744,0.000025409205,0.00015672893,0.000044433807],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016053763,0.0011860233,0.5184427,0.00032437884,0.000036821828,0.06117264,0.0011645154,0.0003598958,0.41284302,0.0002569167,0.0029627064,0.0010898757],"study_design_scores_gemma":[0.0008395762,0.00033258388,0.8225994,0.00006493692,0.00004501892,0.00037451476,0.000089500776,0.00016697039,0.17373176,0.0007426667,0.000830462,0.00018262],"about_ca_topic_score_codex":0.00007087122,"about_ca_topic_score_gemma":0.000027925329,"teacher_disagreement_score":0.30415672,"about_ca_system_score_codex":0.000048322414,"about_ca_system_score_gemma":0.00013763439,"threshold_uncertainty_score":0.4566333},"labels":[],"label_agreement":null},{"id":"W4367840426","doi":"10.1016/j.bbadis.2023.166742","title":"Oxidative stress-induced apoptosis and autophagy: Balancing the contrary forces in spermatogenesis","year":2023,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Autophagy; Cell biology; Biology; Programmed cell death; Epigenetics; Apoptosis; Oxidative stress; DNA damage; Cancer research; Genetics; Endocrinology; Gene","score_opus":0.030840012256825356,"score_gpt":0.3281374225365341,"score_spread":0.29729741027970874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4367840426","genre_codex":"empirical","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.54271173,0.45419994,0.0000023951368,0.0004294621,0.00007639997,0.0015969761,0.0008440448,0.00007804819,0.000061028113],"genre_scores_gemma":[0.37128097,0.62702674,0.000031128704,0.00039008164,0.00009966938,0.0002973688,0.00070389936,0.00014883353,0.000021307578],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962073,0.0005459066,0.0010285402,0.0009814426,0.0006609992,0.00057581597],"domain_scores_gemma":[0.99703866,0.00040745892,0.00070478924,0.0012236458,0.00009794617,0.00052751624],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024441525,0.00091072265,0.0023289812,0.00047762986,0.00011757186,0.000075887234,0.0005778321,0.00031350154,0.000035927478],"category_scores_gemma":[0.00020156708,0.0006519037,0.0012637428,0.00096083747,0.00029908147,0.00013645049,0.000293437,0.00046737364,0.000020484767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030091167,0.006994723,0.00007652073,0.1399092,0.022864806,0.0019192362,0.0020322984,0.000005414699,0.5806979,0.0025276726,0.0013989214,0.23856421],"study_design_scores_gemma":[0.0037482188,0.0005270022,0.005212965,0.04158596,0.016323358,0.000016484324,0.0003847832,0.000114409166,0.926442,0.00052541983,0.0029394615,0.0021799153],"about_ca_topic_score_codex":0.000054232703,"about_ca_topic_score_gemma":0.0000018817865,"teacher_disagreement_score":0.34574413,"about_ca_system_score_codex":0.000093330695,"about_ca_system_score_gemma":0.0008817072,"threshold_uncertainty_score":0.9995932},"labels":[],"label_agreement":null},{"id":"W4368365214","doi":"10.1038/s41467-023-38165-6","title":"Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institute on Aging; National Institute on Alcohol Abuse and Alcoholism; Lee Kong Chian School of Medicine, Nanyang Technological University; U.S. Department of Health and Human Services; National Institutes of Health; Azrieli Foundation; Office of Extramural Research, National Institutes of Health; Nanyang Technological University","keywords":"Autophagy; Steatosis; Fatty liver; Mitophagy; Lysosome; Endocytosis; Flux (metallurgy); Mitochondrion; Phospholipidosis; Cell biology; Nonalcoholic fatty liver disease; Chemistry; Biochemistry; Biology; Endocrinology; Internal medicine; Disease; Medicine; Enzyme","score_opus":0.029843806493439685,"score_gpt":0.3271559692293822,"score_spread":0.2973121627359425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4368365214","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9788292,0.017426437,0.00005288633,0.0025319909,0.00008576587,0.0005148414,0.000030215382,0.000115700524,0.00041295643],"genre_scores_gemma":[0.98859406,0.00972859,0.00057817186,0.0002403566,0.00005669629,0.000115943694,0.00051868486,0.00001767384,0.00014980239],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99906707,0.00013225192,0.0002772766,0.00019277852,0.0001983453,0.00013224997],"domain_scores_gemma":[0.99829143,0.00012514522,0.000112217465,0.0012126884,0.0001493095,0.000109177236],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002511797,0.0001121432,0.00020400388,0.00036171483,0.00012866016,0.000013088263,0.00021717812,0.00018277556,0.000014247592],"category_scores_gemma":[0.00022303988,0.00010621048,0.00006473522,0.00085952313,0.00013762324,0.00017954265,0.000101285,0.00041211073,0.000025051502],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022334931,0.0029969115,0.514612,0.0006887612,0.0005878858,0.00007567529,0.00729862,0.0001825835,0.23257938,0.15591358,0.0058593242,0.07697177],"study_design_scores_gemma":[0.00083110936,0.000033683496,0.9858394,0.00006645087,0.00010725415,0.0000027315675,0.0000795831,0.004575845,0.004529014,0.00065293,0.0031972313,0.00008473086],"about_ca_topic_score_codex":0.0000556106,"about_ca_topic_score_gemma":0.00010783396,"teacher_disagreement_score":0.4712274,"about_ca_system_score_codex":0.000038349048,"about_ca_system_score_gemma":0.00010007934,"threshold_uncertainty_score":0.43311375},"labels":[],"label_agreement":null},{"id":"W4376114788","doi":"10.1038/s41569-023-00885-z","title":"A role for lipophagy in atherosclerosis","year":2023,"lang":"en","type":"review","venue":"Nature Reviews Cardiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; University of Ottawa","keywords":"Autophagy; Lipid metabolism; Medicine; Lipid droplet; Cell biology; Internal medicine; Biochemistry; Biology","score_opus":0.08960164168117978,"score_gpt":0.426396237572496,"score_spread":0.3367945958913162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376114788","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000030876297,0.9927347,0.0000191313,0.00004257426,0.00067076227,0.005658394,0.0001469632,0.00010916626,0.00061526394],"genre_scores_gemma":[0.0000029068988,0.99217993,0.00020311892,0.000539183,0.0017032593,0.0037534938,0.0006163828,0.00016511291,0.0008366177],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9968926,0.0005185661,0.0011070835,0.0007863767,0.00014650695,0.0005489213],"domain_scores_gemma":[0.9980568,0.0004454419,0.00039592097,0.0008865521,0.000060322312,0.00015494441],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0010063772,0.00061816914,0.0072040875,0.0003764883,0.00004179597,0.000009175466,0.00031625674,0.0023276254,0.00003420349],"category_scores_gemma":[0.00058123155,0.0004218087,0.0030841227,0.00071806286,0.000064033404,0.00002531081,0.0000723804,0.001532113,0.00048128297],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021780412,0.000032755626,0.000009461215,0.03190472,0.00053952937,0.000042357842,0.000011319598,1.2941912e-7,0.0000019678982,0.00028655966,0.0066675707,0.9604818],"study_design_scores_gemma":[0.0006022091,0.00013197397,0.00006858286,0.021638602,0.0021086063,0.00012875797,0.0000027608335,9.117326e-7,5.9228705e-7,0.0002828001,0.9747306,0.00030358945],"about_ca_topic_score_codex":0.000002734199,"about_ca_topic_score_gemma":0.000004343424,"teacher_disagreement_score":0.96806306,"about_ca_system_score_codex":0.00020025528,"about_ca_system_score_gemma":0.0004066396,"threshold_uncertainty_score":0.9998234},"labels":[],"label_agreement":null},{"id":"W4376279371","doi":"10.1101/2023.05.10.540213","title":"Upregulated pexophagy limits the capacity of selective autophagy","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Occupational Cancer Research Centre; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Autophagy; Cell biology; Downregulation and upregulation; Peroxisome; Organelle; ATG8; Mitochondrion; Mitophagy; Protein degradation; Biology; Chemistry; Biochemistry; Apoptosis; Gene","score_opus":0.02938787262475014,"score_gpt":0.25169687022366644,"score_spread":0.22230899759891629,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376279371","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99362934,0.001857243,0.00024168733,0.0004216388,0.0012125109,0.0014788471,0.00030785368,0.0008188162,0.000032093372],"genre_scores_gemma":[0.99739623,0.00047232534,0.00062419183,0.000365733,0.0005982235,0.00026016732,0.0000010583697,0.00022393173,0.000058123856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99661916,0.00024016005,0.000771259,0.0010006581,0.00071089953,0.0006578614],"domain_scores_gemma":[0.9958492,0.00019503472,0.0006355864,0.0020048702,0.0009723153,0.00034299784],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00065338775,0.00067180453,0.0010608662,0.0003165408,0.0001949526,0.00006261425,0.00063216686,0.00075111893,0.00010109139],"category_scores_gemma":[0.00039204676,0.00054428127,0.00046680533,0.0010171648,0.00038823838,0.0000860239,0.0003109368,0.0012463976,0.00014041782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033625017,0.0005555255,0.0038854443,0.0010640316,0.0021354938,0.00022677133,0.000092046495,0.00013562487,0.9885671,0.0012259462,0.0017712783,0.000004480203],"study_design_scores_gemma":[0.00079837226,0.00011784716,0.36569455,0.0004056175,0.00047973648,5.690822e-8,0.0000031436346,0.00046268452,0.63130265,0.000025331972,0.00035167387,0.0003583003],"about_ca_topic_score_codex":0.00012654258,"about_ca_topic_score_gemma":0.0000021525802,"teacher_disagreement_score":0.3618091,"about_ca_system_score_codex":0.0002906998,"about_ca_system_score_gemma":0.0012087084,"threshold_uncertainty_score":0.99970084},"labels":[],"label_agreement":null},{"id":"W4376504845","doi":"10.1101/2023.05.12.540513","title":"Fluctuation of lysosomal protein degradation in neural stem cells of postnatal mouse brain","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Japan Society for the Promotion of Science; Japan Agency for Medical Research and Development","keywords":"Neural stem cell; Autophagy; Dentate gyrus; Hippocampal formation; Cell biology; Lysosome; Immunostaining; Stem cell; Protein degradation; Biology; Neuroscience; Intracellular; Chemistry; Biochemistry; Immunohistochemistry; Immunology; Enzyme; Apoptosis","score_opus":0.020630657610693146,"score_gpt":0.24269825352072083,"score_spread":0.22206759591002767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376504845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99685806,0.00043393034,0.0002067645,0.0001709725,0.00028277902,0.0015652844,0.00031367855,0.0001670694,0.0000014538588],"genre_scores_gemma":[0.9987518,0.0000487122,0.00073157216,0.000052917087,0.00012723534,0.0001444936,0.0000030483347,0.00010585998,0.00003431615],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99769825,0.00014541534,0.0007977829,0.0005595098,0.00050160923,0.0002974062],"domain_scores_gemma":[0.99797153,0.00006490597,0.0005995083,0.00085121894,0.0003714412,0.00014139997],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045664515,0.00034536052,0.0006660539,0.0005087348,0.000028184222,0.00002032856,0.00025002318,0.0003995299,0.00002774666],"category_scores_gemma":[0.0001010692,0.0003643289,0.0001778728,0.0005384891,0.00009830563,0.000116989264,0.00016154337,0.00044804718,0.000016713988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024965924,0.0002584832,0.0041174707,0.0012070118,0.0001251157,0.000087937835,0.000024626945,0.00012241995,0.99356526,0.0002014448,0.000033984696,0.0000065979802],"study_design_scores_gemma":[0.0011456741,0.0001328814,0.12594043,0.0005557833,0.000068583075,1.4171488e-8,0.0000076208,0.0015174585,0.8703811,0.0000015591347,0.000013259419,0.00023563032],"about_ca_topic_score_codex":0.00011701619,"about_ca_topic_score_gemma":0.0000034348243,"teacher_disagreement_score":0.123184144,"about_ca_system_score_codex":0.00016386191,"about_ca_system_score_gemma":0.000573496,"threshold_uncertainty_score":0.99988085},"labels":[],"label_agreement":null},{"id":"W4376604893","doi":"10.1016/j.arr.2023.101955","title":"Mitochondrial dysfunction in aging","year":2023,"lang":"en","type":"review","venue":"Ageing Research Reviews","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":304,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Manitoba","funders":"Nutrition Scientific Research Foundation of BYHEALTH; Hebei North University; Fondation Brain Canada; ALS Society of Canada","keywords":"Mitophagy; Mitochondrion; Senescence; Cell biology; Reactive oxygen species; Biology; Ageing; Organelle; Oxidative stress; Biochemistry; Autophagy; Genetics","score_opus":0.3489611002747354,"score_gpt":0.5229802838760285,"score_spread":0.17401918360129304,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376604893","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000008983599,0.99301076,0.000009671908,0.000072637886,0.0007194271,0.004362133,0.000005723691,0.000108731416,0.0017019464],"genre_scores_gemma":[5.5959555e-7,0.9857347,0.000085849344,0.00005979715,0.0016893082,0.0013439304,0.0001729664,0.00013169857,0.010781199],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99479586,0.0016487476,0.001191901,0.0007354248,0.0008242823,0.0008037739],"domain_scores_gemma":[0.99768764,0.0007291349,0.00022524629,0.0009961049,0.000098728015,0.00026312406],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.003977428,0.00039598357,0.0027440868,0.0012512937,0.00014145461,0.00007156138,0.00034814596,0.00034040853,0.000315023],"category_scores_gemma":[0.0021650302,0.00028258524,0.0008827361,0.0025976542,0.00010158356,0.00009137487,0.00017990712,0.0020605843,0.0060523427],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012294662,0.000058225396,0.0000026672255,0.05224205,0.00008360239,0.0014272402,0.000041121893,3.6229448e-8,0.0000028028978,0.000047705158,0.014257757,0.9318245],"study_design_scores_gemma":[0.00038311066,0.000079152815,0.000016227285,0.12179311,0.00021954188,0.000029122912,0.000008788514,0.0000031494235,7.30046e-7,0.00013106802,0.8771558,0.00018020428],"about_ca_topic_score_codex":0.00010269817,"about_ca_topic_score_gemma":0.000033245342,"teacher_disagreement_score":0.93164426,"about_ca_system_score_codex":0.00047587475,"about_ca_system_score_gemma":0.00065375096,"threshold_uncertainty_score":0.9999626},"labels":[],"label_agreement":null},{"id":"W4378619311","doi":"10.3390/curroncol30060406","title":"Targeting Pro-Survival Autophagy Enhanced GSK-3β Inhibition-Induced Apoptosis and Retarded Proliferation in Bladder Cancer Cells","year":2023,"lang":"en","type":"article","venue":"Current Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autophagy; Apoptosis; Gene knockdown; Cancer research; TFEB; Growth inhibition; Bladder cancer; Cancer cell; Cytotoxic T cell; Medicine; Cell biology; Cancer; Pharmacology; Chemistry; Biology; In vitro; Internal medicine; Biochemistry","score_opus":0.08501660427248044,"score_gpt":0.4016069373364094,"score_spread":0.316590333063929,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378619311","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99490166,0.00085562706,0.000079674326,0.0010603467,0.0015284909,0.0009811284,0.000013730031,0.00016471418,0.00041463546],"genre_scores_gemma":[0.99693453,0.0013341957,0.00007778382,0.00023801428,0.00056103955,0.0005470214,0.0001429995,0.000028619294,0.0001358125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99842614,0.00015608358,0.00039944347,0.00042021228,0.00021244134,0.00038566353],"domain_scores_gemma":[0.9993669,0.000092359405,0.00013150928,0.00015395331,0.00011235188,0.00014292075],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031654304,0.00019270406,0.00041891725,0.00020936549,0.00009277769,0.000015272288,0.000048885955,0.00018023455,0.00025011736],"category_scores_gemma":[0.00008972829,0.00017763869,0.00006057336,0.0004086965,0.00006381301,0.00009712654,0.000049195638,0.0003224935,0.00006919899],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042001778,0.0005678339,0.0036358591,0.0002559841,0.0000993783,0.00003554647,0.002468487,0.00005218361,0.9447513,0.00015115678,0.0024012728,0.045160938],"study_design_scores_gemma":[0.007209488,0.0007187735,0.02464923,0.00029349426,0.000160313,0.000005754018,0.00057720154,0.004881908,0.9549171,0.0005975503,0.0055842,0.00040504025],"about_ca_topic_score_codex":0.000018603354,"about_ca_topic_score_gemma":0.00002012773,"teacher_disagreement_score":0.0447559,"about_ca_system_score_codex":0.00020109583,"about_ca_system_score_gemma":0.00034735448,"threshold_uncertainty_score":0.72438955},"labels":[],"label_agreement":null},{"id":"W4378674627","doi":"10.1152/physiol.2023.38.s1.5735257","title":"Effects of omega-3 supplementation on markers of autophagy, apoptosis and mitochondrial area density","year":2023,"lang":"en","type":"article","venue":"Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Queen's University; University of Waterloo","funders":"","keywords":"Mitochondrion; Apoptosis; Autophagy; Internal medicine; Endocrinology; mitochondrial fusion; Biology; Mitochondrial fission; Oxidative phosphorylation; Beta oxidation; Chemistry; Biochemistry; Metabolism; Mitochondrial DNA; Medicine","score_opus":0.010597982726447314,"score_gpt":0.2784069163491167,"score_spread":0.2678089336226694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378674627","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99921983,0.000042499658,0.000010562842,0.000107005624,0.00020635853,0.00028316362,0.000013672021,0.000028026832,0.000088872046],"genre_scores_gemma":[0.99935514,0.0001379556,0.00006903305,0.00018411735,0.00007385337,0.000022026616,0.000080910904,0.000008278004,0.00006870012],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994521,0.000052822666,0.00014082792,0.00014892635,0.0000884595,0.00011685939],"domain_scores_gemma":[0.99951077,0.00022036997,0.00007584344,0.00012442376,0.000031262924,0.000037309837],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003651171,0.00007817748,0.00025843998,0.0000918662,0.00002078115,8.5674947e-7,0.000032101747,0.000050572326,0.00005570859],"category_scores_gemma":[0.00005008958,0.0000662657,0.00006166695,0.0001241041,0.0000875427,0.00001820114,0.000023282935,0.000047146976,0.00000969811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019492089,0.00012589025,0.00077978923,0.000257346,0.0001396464,0.0000037997247,0.0001387156,0.0000040110576,0.99283373,0.00022983183,0.0021949087,0.0013430909],"study_design_scores_gemma":[0.0019281653,0.00070486346,0.31838295,0.000035113706,0.00006514006,6.3824365e-7,0.000029955883,0.00007644443,0.67789143,0.0008026622,0.000045740027,0.000036927988],"about_ca_topic_score_codex":0.00003090927,"about_ca_topic_score_gemma":7.3316284e-7,"teacher_disagreement_score":0.31760314,"about_ca_system_score_codex":0.000010218569,"about_ca_system_score_gemma":0.000021815484,"threshold_uncertainty_score":0.27022368},"labels":[],"label_agreement":null},{"id":"W4380346095","doi":"10.20944/preprints202306.0695.v1","title":"Autophagy Inhibition via Hydroxychloroquine or 3-Methyladenine Enhances Chemotherapy-Induced Apoptosis in Neuro-blastoma and Glioblastoma","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Western University; University of Windsor; Centre for Addiction and Mental Health","funders":"","keywords":"Temozolomide; Autophagy; Cisplatin; Neuroblastoma; Chemotherapy; Medicine; Hydroxychloroquine; Cancer research; Apoptosis; Pharmacology; U87; Cancer; Dacarbazine; Internal medicine; Biology; Glioblastoma; Cell culture","score_opus":0.07628284170337128,"score_gpt":0.35184619561900643,"score_spread":0.27556335391563513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380346095","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99328643,0.00036768365,0.0000928721,0.002313519,0.00081317936,0.0018979434,0.000030717532,0.00078893726,0.00040871743],"genre_scores_gemma":[0.9939895,0.0014493851,0.00012855,0.0010772077,0.0005833855,0.00066240155,0.0000884271,0.00022688524,0.001794223],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99522376,0.00022528645,0.0011295901,0.001946621,0.0007177357,0.00075699814],"domain_scores_gemma":[0.9971566,0.00026030486,0.0005124503,0.0014840853,0.00015553947,0.000431017],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0006694335,0.0008725691,0.0013626515,0.00083604816,0.00011950345,0.000041696312,0.00037608977,0.00080008793,0.0016224696],"category_scores_gemma":[0.00037625272,0.0008086739,0.0003429177,0.0007279677,0.00020390814,0.00018766997,0.0010514271,0.0015296942,0.00080017134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0063423323,0.0012638505,0.04911561,0.0014655752,0.00071451673,0.00082353945,0.0021027464,0.000079253914,0.9289916,0.00003014629,0.00014152296,0.008929266],"study_design_scores_gemma":[0.0034022739,0.000488049,0.2780226,0.0009052106,0.00014997719,0.000076191296,0.000077330595,0.0009063213,0.71412206,0.0010005011,0.00027548007,0.0005739876],"about_ca_topic_score_codex":0.0002954442,"about_ca_topic_score_gemma":0.00011115829,"teacher_disagreement_score":0.22890699,"about_ca_system_score_codex":0.00024505268,"about_ca_system_score_gemma":0.00032203042,"threshold_uncertainty_score":0.9999778},"labels":[],"label_agreement":null},{"id":"W4380422015","doi":"10.1080/15548627.2023.2224206","title":"PHAF1/MYTHO is a novel autophagy regulator that controls muscle integrity","year":2023,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Horizon 2020 Framework Programme; Fonds de Recherche du Québec - Santé; Associazione Italiana per la Ricerca sul Cancro","keywords":"Autophagy; Biology; mTORC1; Downregulation and upregulation; Skeletal muscle; Cell biology; Muscle atrophy; Regulator; SDHA; Myocyte; Proteostasis; Endocrinology; PI3K/AKT/mTOR pathway; Mitochondrion; Signal transduction; Biochemistry; Gene","score_opus":0.05473673559402828,"score_gpt":0.32541348222956,"score_spread":0.27067674663553176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380422015","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9850652,0.0016688876,0.0006464164,0.003949294,0.0010216204,0.001006403,0.00017167159,0.0016063508,0.004864155],"genre_scores_gemma":[0.97030604,0.00021606838,0.0005647439,0.00831463,0.0006056165,0.00015775893,0.00012253631,0.0001146999,0.019597907],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99694276,0.00007547219,0.0005334501,0.0007920902,0.0007547637,0.0009014679],"domain_scores_gemma":[0.9977641,0.00021366769,0.00019386559,0.0011419874,0.00016073097,0.00052562094],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00049403234,0.0004790892,0.0008353543,0.0003385486,0.0002331454,0.00007263673,0.0003628739,0.00036904524,0.0024445704],"category_scores_gemma":[0.0001661722,0.00041884976,0.00051397074,0.00083042413,0.00020999614,0.00026772675,0.00014191635,0.00058883737,0.002289386],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021541812,0.003771475,0.006701232,0.0007930913,0.002933345,0.0030288892,0.006293457,0.00003596437,0.57429916,0.02429931,0.24601357,0.12967633],"study_design_scores_gemma":[0.013586977,0.00059569423,0.54544693,0.00027185457,0.00045479715,0.00020488135,0.00035955085,0.0075075366,0.23043835,0.00519942,0.19501024,0.00092378905],"about_ca_topic_score_codex":0.00009172665,"about_ca_topic_score_gemma":0.0000041511357,"teacher_disagreement_score":0.5387457,"about_ca_system_score_codex":0.00014843103,"about_ca_system_score_gemma":0.0003428547,"threshold_uncertainty_score":0.9998263},"labels":[],"label_agreement":null},{"id":"W4380446145","doi":"10.1101/2023.06.13.544784","title":"Pain hypersensitivity is dependent on autophagy protein Beclin 1 in males but not females","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"BECN1; Autophagy; Neuropathic pain; Medicine; Neurotrophic factors; Chronic pain; Inflammation; Glutamate receptor; Hippocampal formation; Receptor; Neuroscience; Endocrinology; Immunology; Internal medicine; Biology; Anesthesia; Genetics","score_opus":0.04000225762458518,"score_gpt":0.2685780703795462,"score_spread":0.228575812754961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380446145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936249,0.00062938215,0.00018328568,0.0014591103,0.00061262824,0.0021489977,0.00052323146,0.0007999529,0.00001849921],"genre_scores_gemma":[0.9948509,0.00026160676,0.0010036189,0.0021946675,0.0006546476,0.00061188714,0.0000019636889,0.0002735287,0.00014720297],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.995334,0.00052034465,0.00080694165,0.0016150814,0.000871822,0.00085179886],"domain_scores_gemma":[0.9968001,0.00023287721,0.00039629944,0.0018354426,0.00027835573,0.00045692475],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0019004446,0.00085409207,0.0011617462,0.0006421159,0.00013617241,0.00011601926,0.00038822467,0.00091287674,0.000112281785],"category_scores_gemma":[0.0006439573,0.0008790694,0.000374823,0.0005010622,0.00017300896,0.00008968319,0.00036466896,0.0014662103,0.00055663567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009438113,0.0013536888,0.02522376,0.0018919419,0.0006262548,0.008004446,0.000053754535,0.00007680851,0.96095365,0.00058935164,0.00024235522,0.000040149782],"study_design_scores_gemma":[0.0012859487,0.00018336225,0.45006582,0.0015324547,0.00011595374,7.2412995e-8,0.0000113525375,0.00065983407,0.545137,0.000008132733,0.0003166903,0.00068341545],"about_ca_topic_score_codex":0.00026082588,"about_ca_topic_score_gemma":0.000021126323,"teacher_disagreement_score":0.42484206,"about_ca_system_score_codex":0.0005647265,"about_ca_system_score_gemma":0.0010331533,"threshold_uncertainty_score":0.999366},"labels":[],"label_agreement":null},{"id":"W4381309829","doi":"10.1007/s00018-023-04827-3","title":"Loss of functional peroxisomes leads to increased mitochondrial biogenesis and reduced autophagy that preserve mitochondrial function","year":2023,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; SickKids Foundation; Heart and Stroke Foundation; Hospital for Sick Children","funders":"University of Toronto; Canadian Institutes of Health Research; Hospital for Sick Children; Genome British Columbia; University of Victoria","keywords":"Peroxisome; Mitochondrion; Mitochondrial biogenesis; Cell biology; Autophagy; Biogenesis; Biology; Organelle biogenesis; Hepatocyte; Function (biology); Biochemistry; Gene","score_opus":0.024961643929949703,"score_gpt":0.26659222361608603,"score_spread":0.24163057968613633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381309829","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993422,0.0026075954,0.0018835468,0.00060753233,0.0007553406,0.000438382,0.00002158423,0.000074041665,0.00019002018],"genre_scores_gemma":[0.99832284,0.00015840706,0.00030436763,0.0004999765,0.00032520748,0.00003951141,0.0000521604,0.000017031813,0.00028048144],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99830925,0.00008739496,0.00023330672,0.00051975675,0.0005594052,0.00029090536],"domain_scores_gemma":[0.99917513,0.000065874054,0.000077080476,0.00022756573,0.000082844206,0.00037151194],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020690005,0.00018667232,0.00030457636,0.00032748506,0.00021525509,0.000040138686,0.000114484545,0.00010906627,0.00009899171],"category_scores_gemma":[0.00017484362,0.00015528982,0.00012726773,0.0006446235,0.00042764048,0.000119466924,0.00009292271,0.000071280454,0.000016321295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005795018,0.00006513618,0.0018454446,0.00005987049,0.00008195883,0.000036990747,0.00015656403,0.0000564722,0.9954732,0.0003226098,0.0008865086,0.00043571353],"study_design_scores_gemma":[0.0021745192,0.0008548496,0.041743875,0.0000664389,0.00020571913,0.000015719294,0.00031872105,0.0004503583,0.9523878,0.00059329026,0.0009544566,0.0002342355],"about_ca_topic_score_codex":0.000063497864,"about_ca_topic_score_gemma":0.0000023686644,"teacher_disagreement_score":0.04308541,"about_ca_system_score_codex":0.0000113545775,"about_ca_system_score_gemma":0.000232684,"threshold_uncertainty_score":0.6332535},"labels":[],"label_agreement":null},{"id":"W4382047123","doi":"10.1007/978-1-0716-3338-0_12","title":"Multiplexed Phagosomal Assays for the Detection and Quantification of Bidirectional Exchange Between the Phagolysosomal Lumen and Extracellular Space","year":2023,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Phagolysosome; Phagosome; Cell biology; Macrophage; Phagocytosis; Immune system; Extracellular; Organelle; Biology; Chemistry; Immunology; Biochemistry; In vitro","score_opus":0.0538437744031381,"score_gpt":0.4051816909613374,"score_spread":0.3513379165581993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382047123","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4396519,0.0065140785,0.55216175,0.0008280446,0.00012651956,0.00065172825,0.000015958627,0.00002948798,0.000020519134],"genre_scores_gemma":[0.95294195,0.0005006851,0.045974698,0.000069995585,0.00012125762,0.00022303463,0.000032754124,0.000020105632,0.000115506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988078,0.0005243042,0.00020178755,0.00023654924,0.0000672943,0.00016225556],"domain_scores_gemma":[0.99856144,0.0010659313,0.00009186585,0.00020328964,0.000043763674,0.00003368334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015324714,0.00010333275,0.00021051674,0.000116964504,0.000099865196,0.0000064190585,0.00006734753,0.00012749525,0.000008796791],"category_scores_gemma":[0.0003596688,0.00006520438,0.00006430969,0.0002604668,0.00021931794,0.00001689767,0.000031929856,0.00011824877,7.5816047e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000112702415,0.000020971589,0.005637444,0.000034697725,0.000102145874,0.0000023051123,0.00014573862,0.000005108292,0.8935713,0.00062045146,0.000004261904,0.09974285],"study_design_scores_gemma":[0.0013113278,0.00025763904,0.11241107,0.000013424093,0.00015210954,0.000015590862,0.00014922662,0.0062355786,0.87257725,0.0039535635,0.002835479,0.00008776226],"about_ca_topic_score_codex":0.000039179406,"about_ca_topic_score_gemma":0.000005616381,"teacher_disagreement_score":0.51329005,"about_ca_system_score_codex":0.00001260237,"about_ca_system_score_gemma":0.000019546347,"threshold_uncertainty_score":0.26589575},"labels":[],"label_agreement":null},{"id":"W4382117416","doi":"10.1101/2023.06.23.546123","title":"PINK1 Deficiency Alters Muscle Stem Cell Fate Decision and Muscle Regenerative Capacity","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Mitophagy; PINK1; Cell biology; Parkin; Biology; Mitochondrion; Regulator; Stem cell; Regeneration (biology); Cell fate determination; Myocyte; Autophagy; Genetics; Apoptosis; Transcription factor; Internal medicine; Medicine","score_opus":0.02958216113148878,"score_gpt":0.2449819687556859,"score_spread":0.2153998076241971,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382117416","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99134326,0.0032529023,0.0020800952,0.00018050367,0.0011933572,0.0010581588,0.00029040844,0.00057975063,0.000021581449],"genre_scores_gemma":[0.99443567,0.0014685793,0.0029169829,0.00040316145,0.0003871368,0.00016833097,9.381046e-7,0.00018505208,0.00003414599],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9966355,0.00014469464,0.00061044353,0.0013652432,0.00059898617,0.0006451133],"domain_scores_gemma":[0.99708563,0.00013101692,0.00037016533,0.0014485829,0.0003970012,0.00056761457],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005759383,0.0006512458,0.0007774786,0.0003490728,0.0002784419,0.00015272878,0.0003434706,0.00054597727,0.000046789995],"category_scores_gemma":[0.00007878052,0.00063030986,0.0002291223,0.0005128413,0.00022058161,0.00013798648,0.00043683944,0.0008171711,0.00015044399],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018261641,0.0004950702,0.0039278558,0.0011799867,0.00020688954,0.00045370398,0.00014977758,0.00012782656,0.99165416,0.00043093154,0.0010959525,0.00009521623],"study_design_scores_gemma":[0.0023905297,0.00032212326,0.51962906,0.0011521952,0.00047015378,6.513074e-8,0.000038653296,0.001197048,0.47131556,0.000031496023,0.00222632,0.0012267602],"about_ca_topic_score_codex":0.00007402443,"about_ca_topic_score_gemma":0.0000032386504,"teacher_disagreement_score":0.5203386,"about_ca_system_score_codex":0.0002811143,"about_ca_system_score_gemma":0.0005184954,"threshold_uncertainty_score":0.99961483},"labels":[],"label_agreement":null},{"id":"W4382632625","doi":"10.1128/mbio.00795-23","title":"<i>Toxoplasma gondii</i> inhibits the expression of autophagy-related genes through AKT-dependent inactivation of the transcription factor FOXO3a","year":2023,"lang":"en","type":"article","venue":"mBio","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Government of Canada; Armand-Frappier Foundation","keywords":"Protein kinase B; Autophagy; Toxoplasma gondii; PI3K/AKT/mTOR pathway; Phosphorylation; Cell biology; Vacuole; Transcription factor; Biology; Chemistry; Signal transduction; Gene; Cytoplasm; Genetics; Apoptosis","score_opus":0.022966577565885448,"score_gpt":0.2698001054241761,"score_spread":0.24683352785829066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382632625","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968337,0.0006093101,0.00015659205,0.00081684825,0.00036142953,0.00055201945,0.00004574696,0.00008744917,0.00053692254],"genre_scores_gemma":[0.99830425,0.00023524788,0.00002462071,0.00018622639,0.000052422412,0.000026807713,0.00004693833,0.000022317665,0.0011011591],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988113,0.00009627065,0.00035456262,0.00017847867,0.0003956576,0.00016371434],"domain_scores_gemma":[0.99921227,0.00006575749,0.00020857558,0.0003960626,0.000082997154,0.000034363573],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013330395,0.00013621278,0.00022094487,0.00005338133,0.0001086976,0.000006393812,0.00015140475,0.00013682625,0.0001423092],"category_scores_gemma":[0.000031481544,0.000074467636,0.0001775561,0.00043575227,0.00010555485,0.00011750439,0.00003743767,0.00016480415,0.000021572867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015603575,0.00013366954,0.0012269551,0.00007547101,0.000059973314,0.000002410733,0.0023820845,0.00003321829,0.99196607,0.00033225032,0.00034035073,0.0032915107],"study_design_scores_gemma":[0.0012261561,0.00011607062,0.047811814,0.00017675769,0.0000641358,0.0000050910576,0.00031064663,0.00010638213,0.9481141,0.0009610476,0.0010391447,0.00006864908],"about_ca_topic_score_codex":0.000048509555,"about_ca_topic_score_gemma":0.000004337983,"teacher_disagreement_score":0.046584856,"about_ca_system_score_codex":0.000039308197,"about_ca_system_score_gemma":0.00007178256,"threshold_uncertainty_score":0.3036702},"labels":[],"label_agreement":null},{"id":"W4382776046","doi":"10.1016/j.celrep.2023.112708","title":"Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production","year":2023,"lang":"en","type":"article","venue":"Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health, Pakistan; National Institute of Diabetes and Digestive and Kidney Diseases; Klarman Cell Observatory, Broad Institute; National Institute of Allergy and Infectious Diseases; McMaster University; Broad Institute; Washington University in St. Louis; National Institutes of Health; Leona M. and Harry B. Helmsley Charitable Trust","keywords":"Autophagy; Inflammation; Innate immune system; Cell biology; Biology; Cytokine; Downregulation and upregulation; Macrophage; Transcriptome; Context (archaeology); Immune system; Immunology; Gene expression; Gene; Biochemistry; In vitro","score_opus":0.014974843685648323,"score_gpt":0.2694123765395177,"score_spread":0.2544375328538694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382776046","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965215,0.0006537061,0.000059209447,0.000290226,0.00024964998,0.0005366636,0.000014430078,0.000072563605,0.0016020889],"genre_scores_gemma":[0.99802744,0.00041619592,0.00020699852,0.000034554174,0.00012468146,0.0000307076,0.00022921848,0.000013130404,0.0009170731],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989151,0.000036710284,0.0003913566,0.00028125837,0.00024025363,0.00013536324],"domain_scores_gemma":[0.9992859,0.000024332756,0.0002873591,0.00019090994,0.00016698713,0.00004453187],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002007906,0.000115301074,0.00024692074,0.00017814702,0.00004851522,0.0000064555356,0.000018428998,0.00007597125,0.00008198819],"category_scores_gemma":[0.00012948462,0.00010760205,0.000053051594,0.0003537844,0.00013832278,0.00025071044,0.0000134112315,0.00009076987,0.000006470236],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023890733,0.00009139889,0.0050474103,0.00012386027,0.00004825893,0.0002795713,0.0014443748,0.00015905773,0.9883422,0.001262603,0.000050829705,0.0029115006],"study_design_scores_gemma":[0.00036899513,0.000037514656,0.50316745,0.000041124516,0.000046275116,0.00011291503,0.00011545331,0.000040528856,0.4936881,0.001426701,0.0009027404,0.000052210635],"about_ca_topic_score_codex":0.000050820017,"about_ca_topic_score_gemma":0.0000061152705,"teacher_disagreement_score":0.49812004,"about_ca_system_score_codex":0.00003153577,"about_ca_system_score_gemma":0.00015151946,"threshold_uncertainty_score":0.4387884},"labels":[],"label_agreement":null},{"id":"W4382936466","doi":"10.3390/ijms241311018","title":"Harnessing Autophagy to Overcome Antigen-Specific T-Cell Dysfunction: Implication for People Living with HIV-1","year":2023,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Institut National de la Recherche Scientifique","funders":"","keywords":"Autophagy; Immune system; Intracellular; Lysosome; Immunology; T cell; Biology; Human immunodeficiency virus (HIV); Immunity; Antigen; Virus; Virology; Medicine; Cell biology; Apoptosis","score_opus":0.043414318808923553,"score_gpt":0.3599062190740986,"score_spread":0.31649190026517504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382936466","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.006547271,0.95728165,0.033575248,0.00045440014,0.0012337397,0.0005839184,0.000027306829,0.00003492624,0.00026150988],"genre_scores_gemma":[0.006578824,0.98765486,0.00431092,0.00022608996,0.0008028526,0.000050258514,0.000024932639,0.000052413598,0.00029883767],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977807,0.000052787665,0.0006376377,0.00032746512,0.0009894308,0.00021199121],"domain_scores_gemma":[0.99811935,0.00022433838,0.00073237385,0.00017593372,0.0005813022,0.00016669156],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006325319,0.00023028397,0.0007242398,0.000692608,0.0001213351,0.00019744408,0.0006235785,0.000090658585,0.000060268492],"category_scores_gemma":[0.00008243128,0.0001611071,0.000461783,0.0006019,0.00007391985,0.00019586491,0.00006244806,0.00018969938,0.000047784142],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024410129,0.0006429269,0.00029747828,0.003149985,0.0017537635,0.0007741554,0.00080554764,0.00047067303,0.0025355518,0.0020303922,0.0026696424,0.98462576],"study_design_scores_gemma":[0.0013817191,0.001216753,0.0023949472,0.029041504,0.0005452288,0.0020281237,0.00023363048,0.00009313639,0.0010930294,0.00034095728,0.96106654,0.00056444405],"about_ca_topic_score_codex":0.00000322732,"about_ca_topic_score_gemma":6.06513e-7,"teacher_disagreement_score":0.98406136,"about_ca_system_score_codex":0.00017617499,"about_ca_system_score_gemma":0.0008219937,"threshold_uncertainty_score":0.65697575},"labels":[],"label_agreement":null},{"id":"W4383264094","doi":"10.1186/s40478-023-01601-1","title":"Mechanisms of metabolic stress induced cell death of human oligodendrocytes: relevance for progressive multiple sclerosis","year":2023,"lang":"en","type":"article","venue":"Acta Neuropathologica Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Children's Hospital; Université de Montréal; McGill University Health Centre; McGill University; Montreal Neurological Institute and Hospital","funders":"International Progressive MS Alliance","keywords":"Multiple sclerosis; Neuroscience; Neurology; Medicine; Relevance (law); Programmed cell death; Biology; Immunology; Apoptosis; Genetics","score_opus":0.1416570199072517,"score_gpt":0.3454761855440517,"score_spread":0.20381916563679997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383264094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965692,0.00096226536,0.00015693996,0.00032671329,0.000036352034,0.00097268703,0.00021909965,0.000149009,0.0006077294],"genre_scores_gemma":[0.99253213,0.0020773425,0.00451695,0.0001483204,0.00001304555,0.00041708123,0.00018183919,0.00003385982,0.00007940791],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870706,0.0001998438,0.0004390226,0.00024840358,0.00017924051,0.00022641955],"domain_scores_gemma":[0.99679667,0.0006170455,0.0004011016,0.0018491263,0.00025393948,0.000082111415],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020307595,0.00016242005,0.00043441376,0.00015798195,0.00023438457,0.0000074630584,0.00075486785,0.00009391261,0.000018155954],"category_scores_gemma":[0.00041855758,0.00013971339,0.00018579283,0.00041723854,0.00016239208,0.000068738766,0.00030581953,0.00019234634,0.000007291197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007087746,0.00077165815,0.0021167137,0.00008863607,0.00003943451,0.000008521996,0.00036286624,0.0000035791775,0.98786783,0.007997422,0.000030092775,0.00064235897],"study_design_scores_gemma":[0.0014986692,0.0007235157,0.17333944,0.0001546287,0.00021656508,0.0000072595562,0.000293507,0.00048709087,0.8204541,0.0025034323,0.00018185149,0.00013989444],"about_ca_topic_score_codex":0.000009815177,"about_ca_topic_score_gemma":0.0000020142886,"teacher_disagreement_score":0.17122273,"about_ca_system_score_codex":0.0000082731885,"about_ca_system_score_gemma":0.000052257736,"threshold_uncertainty_score":0.56973463},"labels":[],"label_agreement":null},{"id":"W4383534489","doi":"10.1186/s40478-023-01604-y","title":"Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations","year":2023,"lang":"en","type":"article","venue":"Acta Neuropathologica Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; McMaster University; University of Manitoba","funders":"Canadian Institutes of Health Research; Cancer Research Society; Natural Sciences and Engineering Research Council of Canada; Manitoba Medical Service Foundation; Canadian Cancer Society; Research Manitoba; Health Sciences Centre Foundation","keywords":"Stem cell; Biology; Cancer research; Autophagy; Cancer stem cell; Glycolysis; Cell biology; Senescence; Anaerobic glycolysis; Tumor progression; Cancer; Apoptosis; Endocrinology; Biochemistry; Metabolism","score_opus":0.03836253282079765,"score_gpt":0.32769031177957875,"score_spread":0.2893277789587811,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383534489","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970622,0.0009466943,0.000005752342,0.001068638,0.000031339165,0.00042737796,0.000047971123,0.00029924212,0.00011078103],"genre_scores_gemma":[0.9980888,0.0010080766,0.00025081664,0.00033472432,0.00002566064,0.000087255736,0.000079020654,0.00003083345,0.00009484944],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9984224,0.00034505106,0.00040622646,0.00038840517,0.00015677615,0.00028113404],"domain_scores_gemma":[0.99775875,0.0005092564,0.00013533424,0.0013578415,0.0000744783,0.00016435482],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027676718,0.00020168762,0.00038052758,0.00026347043,0.0004515386,0.000065241846,0.00036778944,0.00008855022,0.000022503174],"category_scores_gemma":[0.00017946394,0.00018757921,0.00006533504,0.00068406743,0.00057083304,0.00013573427,0.00051250047,0.00028197435,0.000017543924],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014683827,0.00033268752,0.92602533,0.00009172912,0.000058667265,0.0010523867,0.00077430654,0.000046663583,0.067370325,0.00043485072,0.00003558027,0.0036306402],"study_design_scores_gemma":[0.0006938747,0.00017321944,0.9937699,0.00005417794,0.00006345019,0.00037882364,0.000071435796,0.001754807,0.002054035,0.00038104996,0.0004390795,0.00016614827],"about_ca_topic_score_codex":0.00002889581,"about_ca_topic_score_gemma":0.000033656786,"teacher_disagreement_score":0.067744575,"about_ca_system_score_codex":0.00002717884,"about_ca_system_score_gemma":0.000037472706,"threshold_uncertainty_score":0.76492584},"labels":[],"label_agreement":null},{"id":"W4383998913","doi":"10.1080/15548627.2023.2228191","title":"Autophagy-ER stress crosstalk controls mucus secretion and susceptibility to gut inflammation","year":2023,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; Mizutani Foundation for Glycoscience","keywords":"Unfolded protein response; Autophagy; Mucus; Secretion; Biology; Endoplasmic reticulum; BECN1; Cell biology; ATG16L1; Inflammation; NOD2; Immunology; Immune system; Biochemistry; Innate immune system","score_opus":0.01408917528392582,"score_gpt":0.30017331198428393,"score_spread":0.2860841367003581,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383998913","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950281,0.00031082678,0.00022843064,0.001219866,0.00031865365,0.0010528117,0.00007946927,0.00065977155,0.0011020664],"genre_scores_gemma":[0.9950228,0.00008482649,0.00014100922,0.00074107165,0.00040738352,0.00012653126,0.00023149588,0.00004513518,0.0031997699],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980379,0.00008925573,0.00043389987,0.00054625527,0.00041187275,0.0004808278],"domain_scores_gemma":[0.9986569,0.0001336051,0.000103660794,0.0005598637,0.00015830545,0.00038761116],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040392895,0.0002690031,0.00042691804,0.00023238463,0.00019234071,0.00007885274,0.00011370875,0.0001873,0.0006153297],"category_scores_gemma":[0.00023043109,0.00024532454,0.00012741619,0.00048717705,0.00012227622,0.0002158597,0.000092435155,0.00018962125,0.0005986182],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016585271,0.0004032689,0.032866288,0.0005829757,0.00046117487,0.00080697564,0.0044646943,0.00039475266,0.8548312,0.004496907,0.0035870872,0.0954461],"study_design_scores_gemma":[0.0035078228,0.00045611913,0.8928643,0.000105274936,0.00010359703,0.000028015484,0.00022239263,0.004157661,0.09021817,0.0015862125,0.006440969,0.00030946668],"about_ca_topic_score_codex":0.000077768156,"about_ca_topic_score_gemma":0.00003414103,"teacher_disagreement_score":0.859998,"about_ca_system_score_codex":0.00010133446,"about_ca_system_score_gemma":0.00012155683,"threshold_uncertainty_score":0.9999999},"labels":[],"label_agreement":null},{"id":"W4384471003","doi":"10.1016/j.bbamcr.2023.119537","title":"Therapeutic strategies targeting AMPK-dependent autophagy in cancer cells","year":2023,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Wuhan Science and Technology Project; Hubei University of Technology; National Natural Science Foundation of China; University of Alberta","keywords":"Autophagy; AMPK; Cell biology; mTORC1; ULK1; Protein kinase A; PI3K/AKT/mTOR pathway; Kinase; AMP-activated protein kinase; ATG16L1; Chemistry; Cancer cell; Biology; Signal transduction; Cancer; Biochemistry; Apoptosis","score_opus":0.1402681795700697,"score_gpt":0.46544534942200533,"score_spread":0.3251771698519356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384471003","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03404617,0.95860213,0.000013937692,0.0002982249,0.0003514374,0.003481783,0.00019024234,0.00026431205,0.002751778],"genre_scores_gemma":[0.060983993,0.9345608,0.00006844602,0.00018421563,0.00042056714,0.0010031273,0.00045577573,0.00046750775,0.001855574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99128896,0.001712092,0.0012549015,0.0017695633,0.0021407413,0.0018337276],"domain_scores_gemma":[0.9965989,0.00058175315,0.00043084484,0.0015495587,0.00030437173,0.00053455826],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015292091,0.0011086037,0.0025376137,0.0013821131,0.00022686555,0.00034835935,0.0012470594,0.00087080087,0.00026952845],"category_scores_gemma":[0.000055327913,0.000928159,0.0012023927,0.002541736,0.00044113013,0.00015533635,0.0005779946,0.0030703854,0.00079381885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030265478,0.0021508401,2.7505115e-7,0.03863659,0.0019916084,0.0025992116,0.0007212241,0.000015562327,0.8629933,0.0006794806,0.001564089,0.08834519],"study_design_scores_gemma":[0.0026072776,0.0010057669,0.000041284304,0.01818196,0.0017522208,0.000018340172,0.00069741666,0.00015902505,0.7956569,0.0013088242,0.17631917,0.0022517813],"about_ca_topic_score_codex":0.0004379886,"about_ca_topic_score_gemma":0.00001682278,"teacher_disagreement_score":0.17475507,"about_ca_system_score_codex":0.00065292884,"about_ca_system_score_gemma":0.0044377414,"threshold_uncertainty_score":0.9999842},"labels":[],"label_agreement":null},{"id":"W4384926656","doi":"10.1152/japplphysiol.00411.2023","title":"Physiological responses to 9 hours of heat exposure in young and older adults. Part II: Autophagy and the acute cellular stress response","year":2023,"lang":"en","type":"article","venue":"Journal of Applied Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Calgary; Université de Sherbrooke; University of Ottawa","funders":"Canadian Institutes of Health Research; Health Canada; Government of Canada","keywords":"Autophagy; Young adult; Apoptosis; Heat shock protein; Inflammation; Medicine; Heat shock; Western blot; Peripheral blood mononuclear cell; Internal medicine; Endocrinology; Senescence; Ageing; Hsp70; Immunology; Biology; Biochemistry; In vitro","score_opus":0.010286792097786717,"score_gpt":0.26856145399494,"score_spread":0.2582746618971533,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384926656","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978985,0.0007443658,0.0000030694785,0.00083586475,0.00010482923,0.00035167826,0.000019255125,0.000013978929,0.000028416163],"genre_scores_gemma":[0.99839437,0.0007685782,0.000046663583,0.00051927555,0.00016423529,0.000024251965,0.000005924933,0.000014952053,0.000061733444],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99865645,0.0002515223,0.00046052717,0.0002103506,0.00017803388,0.00024313427],"domain_scores_gemma":[0.99897146,0.00043737306,0.00016741625,0.0002184538,0.0000690942,0.00013619295],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006172274,0.0001634322,0.0006729628,0.0001976302,0.00007089022,0.000005527503,0.00012823116,0.00012733809,0.000033981672],"category_scores_gemma":[0.00008146391,0.000095483534,0.00010240931,0.00026140176,0.00032701532,0.000031962212,0.00011145353,0.00028697695,0.0000028887619],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.1668656,0.00028349258,0.0010372422,0.000059738028,0.00031300922,0.00020313004,0.004662656,0.000117381125,0.82452035,0.00036078028,0.00070979184,0.00086685974],"study_design_scores_gemma":[0.009232161,0.0015429872,0.92944765,0.0001943189,0.00011773277,0.00006250574,0.0013807085,0.00008662444,0.0566263,0.001105273,0.000088929286,0.00011479474],"about_ca_topic_score_codex":0.0000061678434,"about_ca_topic_score_gemma":0.0000010225302,"teacher_disagreement_score":0.9284104,"about_ca_system_score_codex":0.000016504579,"about_ca_system_score_gemma":0.00007576639,"threshold_uncertainty_score":0.38937056},"labels":[],"label_agreement":null},{"id":"W4385234821","doi":"10.1016/j.micpath.2023.106270","title":"Streptococcus uberis induced expressions of pro-inflammatory IL-6, TNF-α, and IFN-γ in bovine mammary epithelial cells associated with inhibited autophagy and autophagy flux formation","year":2023,"lang":"en","type":"article","venue":"Microbial Pathogenesis","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"High-end Foreign Experts Recruitment Plan of China; National Natural Science Foundation of China","keywords":"Autophagy; Streptococcus uberis; ATG5; Downregulation and upregulation; Biology; Microbiology; Tumor necrosis factor alpha; Immunology; Apoptosis; Streptococcus; Bacteria","score_opus":0.013591308013212856,"score_gpt":0.23793082442676458,"score_spread":0.22433951641355174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385234821","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99788964,0.00017648851,0.000040373077,0.00011486174,0.00008798381,0.0011024775,0.00034410274,0.00019459694,0.000049476632],"genre_scores_gemma":[0.9986242,0.000119189244,0.00018518216,0.00012881256,0.000068920024,0.00010697015,0.00030366884,0.00005447775,0.0004085557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981888,0.00016286407,0.00058003806,0.00042353413,0.00024575423,0.0003989957],"domain_scores_gemma":[0.9989928,0.0000974188,0.0002677123,0.00032661846,0.00012380829,0.00019162618],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000328101,0.0003102454,0.000557736,0.00045982318,0.00011661375,0.00002843069,0.00010062462,0.00026702246,0.000052075877],"category_scores_gemma":[0.000075625794,0.00024686748,0.000083525796,0.000676977,0.000109172506,0.0002540304,0.00012676415,0.00018016029,0.000011484548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004190085,0.00020529135,0.0023172745,0.00021542129,0.00008876526,0.00026009546,0.0011030162,0.000009125166,0.98647314,0.000011863762,0.00023881458,0.008658172],"study_design_scores_gemma":[0.003606621,0.0003508488,0.2739939,0.0003588386,0.00009294001,0.000020253907,0.00014575043,0.00046209252,0.72058946,0.000033065175,0.00012254901,0.00022367977],"about_ca_topic_score_codex":0.000037226753,"about_ca_topic_score_gemma":0.00004255671,"teacher_disagreement_score":0.27167663,"about_ca_system_score_codex":0.00007670886,"about_ca_system_score_gemma":0.00020230231,"threshold_uncertainty_score":0.99999833},"labels":[],"label_agreement":null},{"id":"W4385248115","doi":"10.1016/j.isci.2023.107475","title":"Autophagy ablation in skeletal muscles worsens sepsis-induced muscle wasting, impairs whole-body metabolism, and decreases survival","year":2023,"lang":"en","type":"article","venue":"iScience","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières; McGill University; McGill University Health Centre; Christie (Canada); Université du Québec à Montréal","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; McGill University Health Centre; Genome Canada; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Wasting; Autophagy; Sepsis; Skeletal muscle; Hypermetabolism; Internal medicine; Endocrinology; Biology; Medicine; Apoptosis; Biochemistry","score_opus":0.02699873174051395,"score_gpt":0.30820298407984803,"score_spread":0.2812042523393341,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385248115","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972324,0.00075463875,0.000041760286,0.0005271468,0.0002786262,0.00025637768,0.000008830428,0.00021342616,0.0006867865],"genre_scores_gemma":[0.9990477,0.000119680706,0.00013812653,0.00019053712,0.00014676066,0.000021714246,0.000020323005,0.000019042838,0.00029612746],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99838936,0.00007389299,0.0002540319,0.00043335388,0.0004181049,0.00043126717],"domain_scores_gemma":[0.9992148,0.00015060979,0.00007618092,0.00026682616,0.000052132422,0.00023941818],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049484684,0.00017223622,0.00027456536,0.00029292383,0.00015687445,0.00004862511,0.00012590976,0.00007265052,0.00007351023],"category_scores_gemma":[0.00029255016,0.00014781719,0.0000745973,0.0010718371,0.00017100517,0.0002729175,0.00007802444,0.0001404726,0.000071456365],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009116071,0.0005187734,0.06064572,0.00013920014,0.00006665946,0.0007821255,0.0038415117,0.00022416071,0.7722595,0.001934413,0.0004253119,0.15907149],"study_design_scores_gemma":[0.0010400465,0.000071639166,0.9772749,0.000089020126,0.000033583292,0.000013557006,0.00060964125,0.008474869,0.010770429,0.000389665,0.0010655889,0.00016706032],"about_ca_topic_score_codex":0.0001468557,"about_ca_topic_score_gemma":0.000047720292,"teacher_disagreement_score":0.9166292,"about_ca_system_score_codex":0.000032964206,"about_ca_system_score_gemma":0.00015313545,"threshold_uncertainty_score":0.602781},"labels":[],"label_agreement":null},{"id":"W4385346881","doi":"10.3390/ijms241512052","title":"Autophagy Inhibition via Hydroxychloroquine or 3-Methyladenine Enhances Chemotherapy-Induced Apoptosis in Neuro-Blastoma and Glioblastoma","year":2023,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Western University; University of Windsor; Centre for Addiction and Mental Health","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Temozolomide; Autophagy; Cisplatin; Neuroblastoma; Medicine; Chemotherapy; Hydroxychloroquine; Cancer research; Dacarbazine; Apoptosis; Pharmacology; Cancer; Oncology; Internal medicine; Biology; Cell culture","score_opus":0.014427647885360544,"score_gpt":0.3108323441740349,"score_spread":0.29640469628867433,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385346881","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938831,0.00035875963,0.00043379216,0.004594308,0.000462909,0.00011006113,0.0000020748987,0.00002875232,0.00012624759],"genre_scores_gemma":[0.99762046,0.00040001108,0.00039624085,0.0013256522,0.00018418103,0.000005349561,0.0000016308402,0.000012983142,0.000053467178],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99819267,0.000056964043,0.0004385951,0.00022310115,0.00088916026,0.00019949998],"domain_scores_gemma":[0.9992425,0.00010613278,0.00025587663,0.000082110855,0.00019076176,0.00012265658],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049891113,0.00013937437,0.00024812456,0.0007943776,0.00005049309,0.000064471315,0.0002444283,0.000058802696,0.00012194641],"category_scores_gemma":[0.00015165129,0.00010310055,0.000105623265,0.00074382103,0.00016789159,0.00029742176,0.000051396324,0.00016745787,0.000012162708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00095643394,0.00016440103,0.00062724424,0.000012087021,0.00010730627,0.0014200222,0.0003530383,0.00009210982,0.9670592,0.00008900642,0.00009164786,0.029027535],"study_design_scores_gemma":[0.0026265872,0.0019419116,0.016123489,0.00022335222,0.000023265808,0.00083595846,0.0001778481,0.0027090465,0.97395617,0.0010476891,0.00020816537,0.00012650936],"about_ca_topic_score_codex":0.000012810334,"about_ca_topic_score_gemma":0.000007179053,"teacher_disagreement_score":0.028901026,"about_ca_system_score_codex":0.000048155012,"about_ca_system_score_gemma":0.00016113392,"threshold_uncertainty_score":0.42043185},"labels":[],"label_agreement":null},{"id":"W4385429673","doi":"10.3390/biom13081196","title":"Polyphenols, Autophagy and Neurodegenerative Diseases: A Review","year":2023,"lang":"en","type":"review","venue":"Biomolecules","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Agricultural Development Fund","keywords":"Autophagy; Neurodegeneration; Neuroinflammation; Cell biology; PI3K/AKT/mTOR pathway; Biology; Neuroscience; Inflammation; Signal transduction; Biochemistry; Medicine; Immunology; Apoptosis","score_opus":0.07903001909304544,"score_gpt":0.4145065945249916,"score_spread":0.3354765754319462,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385429673","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000051035972,0.99702007,0.000015782796,0.00021522607,0.00016898055,0.001666087,0.00037499436,0.0002852911,0.00024845282],"genre_scores_gemma":[0.0000014630727,0.9954358,0.000062439525,0.0014680352,0.00030549502,0.00034630785,0.00061114755,0.00014549738,0.0016238258],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979811,0.00019317395,0.00055685174,0.0006625917,0.00028154274,0.000324771],"domain_scores_gemma":[0.9986434,0.000091757385,0.00023725256,0.0006107459,0.000051784107,0.00036504213],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008872223,0.00054509053,0.0020693974,0.00019516808,0.000083175546,0.00003546436,0.00017123505,0.00018865707,0.00012147118],"category_scores_gemma":[0.00012838902,0.00039120173,0.000617596,0.0005349589,0.0001945412,0.00003709196,0.00012573268,0.00021338047,0.0004104646],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009854934,0.0001050855,6.178772e-7,0.124845445,0.0006359901,0.00089777977,0.000012194176,2.932117e-9,0.0000048026322,0.0008491746,0.009490886,0.86314815],"study_design_scores_gemma":[0.00027499872,0.00012234117,0.00001842693,0.07962798,0.004391165,0.00016937425,0.0000043375385,0.0000019826432,0.000009766822,0.00007310037,0.91496307,0.00034344237],"about_ca_topic_score_codex":0.000010458958,"about_ca_topic_score_gemma":8.2135745e-7,"teacher_disagreement_score":0.9054722,"about_ca_system_score_codex":0.00004882332,"about_ca_system_score_gemma":0.00047650255,"threshold_uncertainty_score":0.99985397},"labels":[],"label_agreement":null},{"id":"W4385622561","doi":"10.1101/2023.08.07.552252","title":"TOM20 Gates PINK1 Activity And Mediates Its Tethering Of The TOM And TIM23 Translocases Upon Mitochondrial Stress","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Parkinson Canada","keywords":"PINK1; Parkin; Mitophagy; Cell biology; Mitochondrion; Ubiquitin ligase; Biology; Translocase; Inner mitochondrial membrane; Ubiquitin; Chemistry; Autophagy; Biochemistry; Chromosomal translocation; Medicine; Parkinson's disease","score_opus":0.019282318527826744,"score_gpt":0.24561336727517202,"score_spread":0.22633104874734528,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385622561","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9920943,0.0047747665,0.00005069626,0.0005289306,0.0008953185,0.0009622288,0.00046509458,0.00022597658,0.0000027062913],"genre_scores_gemma":[0.99684167,0.0020568068,0.0002808405,0.000068881454,0.0005188737,0.000110416455,4.1902842e-7,0.00011178781,0.000010318822],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99806744,0.00012461009,0.0003709347,0.0006921618,0.00038825482,0.0003565801],"domain_scores_gemma":[0.9983045,0.00020229563,0.00028515133,0.00076689373,0.00019103274,0.0002501531],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021533399,0.00044917743,0.0006853802,0.00014726032,0.00013014532,0.00006130699,0.0002304635,0.00040967233,0.0000296198],"category_scores_gemma":[0.00023045695,0.00035607786,0.00016158387,0.00027279806,0.00020402347,0.000097947246,0.00029421295,0.0005661486,0.0000051831007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003190136,0.00017787522,0.013220881,0.0018555418,0.0004601975,0.00006986252,0.00007221657,0.000021216047,0.9836485,0.000092270675,0.000039232913,0.000023201676],"study_design_scores_gemma":[0.001007677,0.000076293734,0.30904686,0.0010394055,0.00032351608,5.340387e-8,0.000007890508,0.00035695694,0.6876995,0.0000045356137,0.0001467756,0.00029056298],"about_ca_topic_score_codex":0.000091532755,"about_ca_topic_score_gemma":0.000012210562,"teacher_disagreement_score":0.295949,"about_ca_system_score_codex":0.000055653778,"about_ca_system_score_gemma":0.00033825292,"threshold_uncertainty_score":0.99988914},"labels":[],"label_agreement":null},{"id":"W4385654848","doi":"10.3390/toxics11080682","title":"Drosophila as a Robust Model System for Assessing Autophagy: A Review","year":2023,"lang":"en","type":"review","venue":"Toxics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Population and Public Health; University of Ottawa","funders":"US-UK Fulbright Commission","keywords":"Autophagy; Drosophila melanogaster; Biology; Model organism; Drosophila (subgenus); Cell biology; Organism; Mechanism (biology); Yeast; Genetic screen; Senescence; Programmed cell death; Computational biology; Cellular stress response; ATG8; Fight-or-flight response; Genetics; Phenotype; Apoptosis; Gene","score_opus":0.2033994764000824,"score_gpt":0.4459670133350339,"score_spread":0.2425675369349515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385654848","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000001720512,0.9909352,0.001126211,0.000113269605,0.00039021464,0.0040633176,0.000185564,0.00067077705,0.0025137402],"genre_scores_gemma":[0.0000027307349,0.98918605,0.0013005192,0.00083975354,0.00075021014,0.0012475138,0.0005345592,0.00030289733,0.0058357446],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.99725646,0.00010083444,0.0010504122,0.0006513309,0.00044706106,0.00049390714],"domain_scores_gemma":[0.9977949,0.00022736826,0.00056015287,0.00096694805,0.00013918987,0.0003113914],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006389671,0.000629403,0.0033996457,0.0001922234,0.00014941943,0.00006546015,0.0003182531,0.00050512736,0.000040807394],"category_scores_gemma":[0.00022813582,0.00048957334,0.00149528,0.0005319078,0.000047731948,0.00008991139,0.000082046376,0.0004620343,0.0005437324],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010347101,0.00008793764,3.203261e-8,0.62363327,0.0006032137,0.00024825946,0.000014559502,0.0000145850745,9.0484764e-7,0.0026084143,0.005645082,0.36713338],"study_design_scores_gemma":[0.00045341687,0.00006734255,1.345709e-7,0.36152506,0.00623587,0.00026615616,0.000008492331,0.0032039778,0.0000027184276,0.00026264804,0.6275667,0.00040746928],"about_ca_topic_score_codex":0.0000021152864,"about_ca_topic_score_gemma":2.0926163e-7,"teacher_disagreement_score":0.6219216,"about_ca_system_score_codex":0.00040113376,"about_ca_system_score_gemma":0.0018315589,"threshold_uncertainty_score":0.9997556},"labels":[],"label_agreement":null},{"id":"W4385715456","doi":"10.1111/acel.13949","title":"Oculopharyngeal muscular dystrophy mutations link the <scp>RNA</scp>‐binding protein <scp>HNRNPQ</scp> to autophagosome biogenesis","year":2023,"lang":"en","type":"article","venue":"Aging Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Azrieli Foundation","keywords":"Autophagy; Biology; Oculopharyngeal muscular dystrophy; Cell biology; RNA-binding protein; Autophagosome; BAG3; RNA; Muscular dystrophy; Genetics; Gene","score_opus":0.014681212191265542,"score_gpt":0.26393272260038747,"score_spread":0.24925151040912194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385715456","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99122006,0.001169675,0.00026951876,0.0013105113,0.00046150645,0.0015921078,0.00007853658,0.00074710796,0.0031510086],"genre_scores_gemma":[0.9748861,0.000122026024,0.0007225764,0.0011673364,0.00096324953,0.00040933787,0.00022950633,0.00014667092,0.021353181],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970924,0.00014826295,0.00047942798,0.0006843369,0.0006783639,0.0009171939],"domain_scores_gemma":[0.9978838,0.00046183643,0.0001689079,0.0008611145,0.00014034967,0.0004839757],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00046800292,0.00042648023,0.00047340206,0.00049332686,0.00059576647,0.00012809865,0.00046263033,0.00017320593,0.00005348966],"category_scores_gemma":[0.0002861466,0.00033862525,0.0003886913,0.0016932728,0.00011850309,0.00015690784,0.00016913925,0.00032991025,0.002521586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012546875,0.00033964828,0.003066505,0.00046603332,0.0006298744,0.0018107997,0.008214121,0.0005474237,0.9665376,0.00038568428,0.011375772,0.006614021],"study_design_scores_gemma":[0.0038463287,0.00055636675,0.044984605,0.0004769363,0.0007995092,0.00006180425,0.0041671298,0.0021045476,0.8482531,0.0011037522,0.09340042,0.0002455109],"about_ca_topic_score_codex":0.00008725407,"about_ca_topic_score_gemma":0.0000026692617,"teacher_disagreement_score":0.11828448,"about_ca_system_score_codex":0.0001195061,"about_ca_system_score_gemma":0.00021453935,"threshold_uncertainty_score":0.9999066},"labels":[],"label_agreement":null},{"id":"W4385755906","doi":"10.1016/j.bj.2023.100635","title":"NLRX1: Versatile functions of a mitochondrial NLR protein that controls mitophagy","year":2023,"lang":"en","type":"review","venue":"Biomedical Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Mitophagy; Mitochondrion; Biology; Cell biology; Apoptosis; Biochemistry; Autophagy","score_opus":0.07757682786411296,"score_gpt":0.36704682628597235,"score_spread":0.2894699984218594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385755906","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009485707,0.9943865,0.0005020444,0.00021756605,0.0027001193,0.0015060445,0.0002554651,0.00009662645,0.0002407799],"genre_scores_gemma":[0.000050527557,0.98875815,0.00034317782,0.00009679431,0.0059946594,0.00017982272,0.00024969666,0.00011051151,0.0042166845],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99636114,0.00026892277,0.0012498735,0.00036576603,0.0012409101,0.0005133712],"domain_scores_gemma":[0.99737155,0.00030066597,0.0008656929,0.0004491853,0.00014374802,0.0008691749],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003904035,0.00045835678,0.0024151085,0.00066379854,0.00014430337,0.000042783322,0.00035728636,0.0006844303,0.0023044427],"category_scores_gemma":[0.00042085713,0.00030562183,0.0016946812,0.00065041974,0.00038104635,0.00006834806,0.00007396918,0.0012011833,0.000564222],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00059309666,0.00090569566,0.0000026027813,0.012766835,0.0033190427,0.0020434216,0.00006379583,3.8636244e-8,0.00037789292,0.00006834074,0.057541575,0.9223177],"study_design_scores_gemma":[0.0032103206,0.000809038,0.000010315534,0.016225692,0.0021678945,0.00094903447,0.00004223383,0.0000032355988,0.000027800077,0.00014797121,0.97616917,0.00023727752],"about_ca_topic_score_codex":0.000009530064,"about_ca_topic_score_gemma":6.201508e-7,"teacher_disagreement_score":0.9220804,"about_ca_system_score_codex":0.00018791272,"about_ca_system_score_gemma":0.0021399723,"threshold_uncertainty_score":0.99993956},"labels":[],"label_agreement":null},{"id":"W4385828734","doi":"10.1038/s41392-023-01503-7","title":"The mitophagy pathway and its implications in human diseases","year":2023,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":768,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Servier; Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"Mitophagy; Computational biology; Biology; Medicine; Genetics; Autophagy","score_opus":0.07304080255075136,"score_gpt":0.36050822580978376,"score_spread":0.2874674232590324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385828734","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002877596,0.99502844,0.000007558473,0.000292818,0.0001422365,0.0013302387,0.00013630615,0.00012977411,0.000055065677],"genre_scores_gemma":[0.004991411,0.99315035,0.0000034308334,0.00009572041,0.00032324748,0.00043364018,0.00024789447,0.00007356358,0.0006807316],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99845207,0.00017927129,0.00048366445,0.00044059558,0.00016266372,0.00028171664],"domain_scores_gemma":[0.9992231,0.00016441339,0.00012394552,0.00024609672,0.000046713496,0.0001957452],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015899849,0.0003519104,0.0007982129,0.00021679865,0.0003758154,0.000051015002,0.000105102634,0.00020498227,0.00015403231],"category_scores_gemma":[0.000008252869,0.00022425482,0.0002788161,0.00045217958,0.00013366112,0.00006717663,0.000009462329,0.0003506101,0.000013170167],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000095571006,0.0001925485,0.000029887431,0.0019053705,0.00053581805,0.000025811732,0.00016218507,2.6655408e-7,0.00048287518,0.0033863392,0.000080336744,0.99310297],"study_design_scores_gemma":[0.0018853294,0.00030196772,0.0025104003,0.002051713,0.00035525678,0.0000781236,0.0000689521,0.0000065966146,0.00025913343,0.0036985779,0.9883745,0.00040950105],"about_ca_topic_score_codex":0.000008396344,"about_ca_topic_score_gemma":0.000004966821,"teacher_disagreement_score":0.9926935,"about_ca_system_score_codex":0.000034621244,"about_ca_system_score_gemma":0.00015819605,"threshold_uncertainty_score":0.9144846},"labels":[],"label_agreement":null},{"id":"W4386113190","doi":"10.3390/ijms241713040","title":"The Combination of Gold and Silver Food Nanoparticles with Gluten Peptides Alters the Autophagic Pathway in Intestinal Crypt-like Cells","year":2023,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Università degli Studi di Milano-Bicocca","keywords":"Autophagy; Vacuole; Gliadin; Acridine orange; Chemistry; Cell biology; Immunofluorescence; Lysosome; Western blot; Gluten; Biology; Biochemistry; Apoptosis; Antibody; Enzyme; Immunology","score_opus":0.014369751031276504,"score_gpt":0.2676946494784173,"score_spread":0.2533248984471408,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386113190","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99574935,0.00075844926,0.00006261346,0.0030261541,0.00017880867,0.00008017635,0.000001445299,0.000005347706,0.00013767506],"genre_scores_gemma":[0.99930364,0.0001350937,0.00020785998,0.00028955113,0.000024836021,0.0000026651662,4.687567e-7,0.0000040832147,0.00003181371],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988347,0.000058936024,0.00024779356,0.000087058856,0.00065949355,0.00011197067],"domain_scores_gemma":[0.99927926,0.00018923577,0.00020657225,0.00006701292,0.00021446025,0.000043472413],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007050045,0.00006455114,0.0000981922,0.00014319172,0.0000576609,0.000056482208,0.00030630597,0.000014527082,0.0000041716935],"category_scores_gemma":[0.00007541187,0.000031558153,0.000049509148,0.00028368243,0.00042795838,0.000120797326,0.000039659917,0.00009395791,0.0000014594198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00075069634,0.00036327523,0.02750624,0.000024198589,0.00043948498,0.00087710435,0.0026071386,0.0025282064,0.92153126,0.016647346,0.00028266886,0.026442362],"study_design_scores_gemma":[0.0033288917,0.0030062336,0.20580293,0.00052141683,0.00005870617,0.000607644,0.0029834919,0.005466854,0.76349616,0.014044848,0.0005289905,0.00015384104],"about_ca_topic_score_codex":0.0000102394315,"about_ca_topic_score_gemma":0.0000078292,"teacher_disagreement_score":0.17829669,"about_ca_system_score_codex":0.000021700162,"about_ca_system_score_gemma":0.00014429618,"threshold_uncertainty_score":0.15768304},"labels":[],"label_agreement":null},{"id":"W4386161533","doi":"10.1038/s41467-023-40929-z","title":"PINK1 and Parkin regulate IP3R-mediated ER calcium release","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Ministry of Science and ICT, South Korea; National Research Foundation of Korea; National Research Foundation","keywords":"Parkin; Calcium; PINK1; Cell biology; Chemistry; Calcium signaling; Biology; Medicine; Internal medicine","score_opus":0.031144315400661617,"score_gpt":0.3461527031529829,"score_spread":0.3150083877523213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386161533","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88732916,0.042548146,0.000020507516,0.058092844,0.00025023113,0.0007542675,0.00011932869,0.0009302776,0.009955244],"genre_scores_gemma":[0.99010104,0.0041810293,0.0004396857,0.0025583282,0.0000685741,0.000050325383,0.0006630793,0.000025263342,0.001912671],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992662,0.00008199914,0.00016367497,0.00016134145,0.00015158181,0.0001751764],"domain_scores_gemma":[0.9979092,0.00023826634,0.000051431096,0.0015373543,0.00009769943,0.00016605415],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015535022,0.000108032014,0.00016136987,0.00012211358,0.00021068219,0.000015352074,0.0002806465,0.00024828347,0.00006312911],"category_scores_gemma":[0.00021933498,0.0000943629,0.000060666087,0.00054550834,0.00016242766,0.00005278939,0.00017434647,0.0006861734,0.00018752363],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012165363,0.0019924769,0.07054104,0.0003277589,0.0019006039,0.0003707079,0.003518602,0.000017965778,0.063613676,0.07385621,0.7276459,0.05499854],"study_design_scores_gemma":[0.0015920225,0.00007694887,0.47031796,0.00009954617,0.0001699488,0.000029591196,0.00012037151,0.0027009312,0.0012215626,0.0014691756,0.52199644,0.00020548701],"about_ca_topic_score_codex":0.000013445468,"about_ca_topic_score_gemma":0.000021774391,"teacher_disagreement_score":0.3997769,"about_ca_system_score_codex":0.000026084826,"about_ca_system_score_gemma":0.00007597796,"threshold_uncertainty_score":0.38480073},"labels":[],"label_agreement":null},{"id":"W4386250262","doi":"10.1186/s13223-023-00821-3","title":"Serum autophagy protein 5 is positively related to T helper 2/T helper 1 ratio, inflammation, and exacerbation in adult asthma patients","year":2023,"lang":"en","type":"article","venue":"Allergy Asthma and Clinical Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Interquartile range; Medicine; Asthma; ATG5; Exacerbation; Internal medicine; Immunology; Gastroenterology; Inflammation; Eosinophil; Autophagy; Biology","score_opus":0.010285360397173857,"score_gpt":0.29594819349935986,"score_spread":0.285662833102186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386250262","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99210995,0.0003329311,0.000025583044,0.006154302,0.00019027361,0.00076713745,0.000012081501,0.0001092216,0.00029853347],"genre_scores_gemma":[0.9938086,0.0008956004,0.00010047648,0.0016845813,0.00006658415,0.000110911526,0.0001231226,0.00003169487,0.0031783727],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9979184,0.00025022036,0.00079604157,0.0005137401,0.00017347289,0.0003480929],"domain_scores_gemma":[0.99906576,0.0001478707,0.00014023265,0.00025877368,0.00022200464,0.00016535482],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031309167,0.00021861706,0.0004338088,0.00021816604,0.000110428286,0.000022780183,0.00008105365,0.00041061713,0.00036594397],"category_scores_gemma":[0.00032823486,0.00019953119,0.00008312045,0.00037310075,0.00017168587,0.00016999831,0.00011756322,0.0003410981,0.0002977924],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011068676,0.0028361198,0.21813302,0.00019227715,0.004282964,0.00059960614,0.01231948,0.000041798052,0.06348448,0.024950666,0.0034098073,0.6586811],"study_design_scores_gemma":[0.00556278,0.001640585,0.98298657,0.00013082928,0.000012939698,0.0000121971,0.0002353225,0.0005883919,0.003780945,0.000857822,0.0039862245,0.000205371],"about_ca_topic_score_codex":0.000061967046,"about_ca_topic_score_gemma":0.000048438767,"teacher_disagreement_score":0.7648536,"about_ca_system_score_codex":0.000034540793,"about_ca_system_score_gemma":0.00008223625,"threshold_uncertainty_score":0.81366456},"labels":[],"label_agreement":null},{"id":"W4386257894","doi":"10.1016/j.cjca.2023.08.022","title":"Autophagy, Clock Genes, and Cardiovascular Disease","year":2023,"lang":"en","type":"review","venue":"Canadian Journal of Cardiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba; St. Boniface Hospital","funders":"","keywords":"Autophagy; Circadian rhythm; Medicine; Circadian clock; Heart failure; Cardiotoxicity; Crosstalk; Disease; Neuroscience; Bioinformatics; Internal medicine; Biology; Apoptosis; Genetics","score_opus":0.059318179582103676,"score_gpt":0.31296939082302877,"score_spread":0.2536512112409251,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386257894","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000063097476,0.9976039,0.00006938556,0.000057480895,0.0010831632,0.0003913927,0.00014765681,0.00001675863,0.0005671808],"genre_scores_gemma":[0.00028653647,0.99560213,0.000022304785,0.00009574524,0.0034535916,0.000017908116,0.00005222406,0.00009363907,0.00037593604],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980023,0.00031615508,0.0006884113,0.00031223556,0.00021914362,0.00046177313],"domain_scores_gemma":[0.99664974,0.000099983365,0.00023865132,0.0005972192,0.00016700351,0.0022474139],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000553314,0.00036438293,0.0033644517,0.00069104956,0.000093939714,0.00002401543,0.00023066268,0.00038256546,0.000032384356],"category_scores_gemma":[0.00018444358,0.0002852018,0.0025362934,0.00025682495,0.00023772354,0.000038736674,0.00002383713,0.00057822,0.00006192494],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020670768,0.0000018475565,0.00009676963,0.004892256,0.011474534,0.016443027,0.000013416899,0.000044763274,7.3760276e-8,0.00017343574,0.0087486375,0.95809054],"study_design_scores_gemma":[0.00046628897,0.00009957193,0.00045240563,0.0031303945,0.010246183,0.0038660965,0.000009175613,0.0000011192683,1.4335008e-7,0.00013777199,0.98137575,0.00021509017],"about_ca_topic_score_codex":0.00019489591,"about_ca_topic_score_gemma":0.00002682483,"teacher_disagreement_score":0.9726271,"about_ca_system_score_codex":0.00019022575,"about_ca_system_score_gemma":0.007252539,"threshold_uncertainty_score":0.99996},"labels":[],"label_agreement":null},{"id":"W4386271459","doi":"","title":"Evaluation of Autophagy Process in Differentiation of Human Induced Pluripotent Stem Cells toward Insulin Producing Cells.","year":2022,"lang":"en","type":"article","venue":"PubMed","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Shiraz University; Shiraz University of Medical Sciences; Islamic Azad University","keywords":"Autophagy; PDX1; Cell biology; Induced pluripotent stem cell; Cellular differentiation; Biology; Homeobox protein NANOG; ATG5; Adipogenesis; Embryonic stem cell; Endocrinology; Mesenchymal stem cell; Genetics; Insulin; Islet; Gene","score_opus":0.06609741752633884,"score_gpt":0.293853022669458,"score_spread":0.22775560514311916,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386271459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967577,0.0005016129,0.000006198974,0.000067954694,0.0002262852,0.0022630836,0.000012939451,0.00002631879,0.00013790104],"genre_scores_gemma":[0.99778384,0.00001095295,0.0000054371967,0.000036167872,0.000050756138,0.0020037498,0.000028185574,0.000019837616,0.000061059895],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997673,0.00025354978,0.00049682404,0.00027878286,0.0010870611,0.00021078785],"domain_scores_gemma":[0.9990667,0.000015187608,0.00032901697,0.0002700978,0.00025241132,0.000066572306],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013481892,0.00011730046,0.00030969063,0.0002572929,0.000047353882,0.0000046225923,0.00011827198,0.00004650915,0.00012051318],"category_scores_gemma":[0.000032797147,0.00011443872,0.000073579205,0.0003829559,0.000021617345,0.000067912595,0.000049738486,0.00017114874,7.431699e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000952985,0.0041973013,0.0090776915,0.0013262653,0.00039548342,0.000016456068,0.016422503,0.004246712,0.51062596,0.00007043276,0.00004164572,0.4526266],"study_design_scores_gemma":[0.0023099226,0.00011042175,0.37377635,0.000020827194,0.00015669609,7.957112e-7,0.0005013682,0.0011140974,0.6217126,0.00022462847,0.000003387735,0.000068849295],"about_ca_topic_score_codex":0.00006803344,"about_ca_topic_score_gemma":0.0000043378554,"teacher_disagreement_score":0.45255774,"about_ca_system_score_codex":0.00027139916,"about_ca_system_score_gemma":0.00018819529,"threshold_uncertainty_score":0.46666756},"labels":[],"label_agreement":null},{"id":"W4386443572","doi":"10.3390/pharmaceutics15092284","title":"Autophagy and Biomaterials: A Brief Overview of the Impact of Autophagy in Biomaterial Applications","year":2023,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; University of Manitoba","keywords":"Autophagy; Biomaterial; Nanotechnology; Computational biology; Cell biology; Medicine; Biology; Materials science; Biochemistry","score_opus":0.24882669625455922,"score_gpt":0.5224822438750258,"score_spread":0.2736555476204666,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386443572","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011466259,0.9849243,0.000003196911,0.000013454454,0.00031351967,0.002262707,0.0008859044,0.00006211326,0.00006855265],"genre_scores_gemma":[0.005028859,0.9942154,0.000030064119,0.00003070469,0.00018087678,0.0002505935,0.0001018657,0.00008287881,0.00007873636],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99783856,0.00022605585,0.0010824654,0.00032375535,0.00024324447,0.00028589356],"domain_scores_gemma":[0.9983798,0.000129156,0.00068224163,0.000612132,0.000063829364,0.00013280236],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035256095,0.0003924935,0.00189172,0.00028521955,0.00003670076,0.000015493382,0.0003061251,0.00025647253,0.00017602],"category_scores_gemma":[0.000038461356,0.00024607807,0.00064255245,0.0009166865,0.00023533274,0.00003913501,0.00019448057,0.00012328778,0.00001786702],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020330901,0.0010900517,0.0001212221,0.1458262,0.0029862453,0.000066750945,0.00029180365,0.0000020556247,0.012742226,0.00089338253,0.0003497732,0.835427],"study_design_scores_gemma":[0.0048405402,0.00029123732,0.0031939587,0.031167097,0.0063989786,0.00028735452,0.000017159078,0.00020162559,0.028631967,0.00084307016,0.923335,0.0007919665],"about_ca_topic_score_codex":0.0001373127,"about_ca_topic_score_gemma":0.0000015033999,"teacher_disagreement_score":0.92298526,"about_ca_system_score_codex":0.00012544943,"about_ca_system_score_gemma":0.0007075691,"threshold_uncertainty_score":0.99999917},"labels":[],"label_agreement":null},{"id":"W4386560484","doi":"10.1038/s41418-023-01215-z","title":"RUNDC1 inhibits autolysosome formation and survival of zebrafish via clasping ATG14-STX17-SNAP29 complex","year":2023,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Wuhan Science and Technology Project; Hubei University; Hubei University of Technology; National Natural Science Foundation of China","keywords":"Autophagy; Cell biology; Zebrafish; Autophagosome; Chemistry; Phosphorylation; Biology; Biochemistry; Apoptosis; Gene","score_opus":0.030317182669668558,"score_gpt":0.26566578374474764,"score_spread":0.23534860107507907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386560484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99609244,0.0002678836,0.0023595097,0.00009070929,0.0001006307,0.00029275139,0.0000119552,0.00009147176,0.00069264055],"genre_scores_gemma":[0.9987817,0.00031526067,0.00005458011,0.00009021179,0.0000669495,0.000009494835,0.0005003496,0.000013920617,0.00016757792],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99919397,0.000034552137,0.00025763627,0.00016883852,0.00018133016,0.00016368006],"domain_scores_gemma":[0.99954367,0.000046905407,0.0001183856,0.00012228706,0.000053291144,0.00011543464],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009428654,0.00012020759,0.0002360717,0.00015066366,0.00009539748,0.000024002737,0.000026835765,0.00007846939,0.000058284277],"category_scores_gemma":[0.000013718211,0.00010813407,0.000049846964,0.00015155149,0.00003145495,0.00015756581,0.000034112054,0.00006418611,0.000013129452],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006200029,0.00048162552,0.17162354,0.0037073798,0.0001775326,0.000021645274,0.0029740832,0.000014216854,0.7815484,0.002880511,0.00052771356,0.035423376],"study_design_scores_gemma":[0.0024425462,0.00017878054,0.9204685,0.00017551416,0.000116074356,0.000006517058,0.00012496073,0.02594236,0.048836533,0.0015074391,0.00006266932,0.0001380892],"about_ca_topic_score_codex":0.000008504339,"about_ca_topic_score_gemma":0.0000043744985,"teacher_disagreement_score":0.748845,"about_ca_system_score_codex":0.000015616013,"about_ca_system_score_gemma":0.000019550436,"threshold_uncertainty_score":0.44095793},"labels":[],"label_agreement":null},{"id":"W4386695379","doi":"10.1242/jcs.260644","title":"Loss of ATG4B and ATG4A results in two-stage cell cycle defects in pancreatic ductal adenocarcinoma cells","year":2023,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver General Hospital; Centre for Advancing Health Outcomes; Pancreas Centre (Canada); University of British Columbia; Canada's Michael Smith Genome Sciences Centre; Simon Fraser University","funders":"Canadian Institutes of Health Research; BC Cancer Foundation; Pancreatic Cancer Action Network","keywords":"Biology; Cancer research; Autophagy; Cell cycle; Cell growth; Apoptosis; Internal medicine; Medicine","score_opus":0.012700268503976165,"score_gpt":0.28797040709776955,"score_spread":0.2752701385937934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386695379","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99652904,0.0012052298,0.0000040961704,0.000105569,0.00012707224,0.00013476014,0.000005294747,0.0000059134677,0.001883031],"genre_scores_gemma":[0.99878454,0.0005167735,0.00020190842,0.0000623438,0.000052996915,8.8891613e-7,5.5214014e-7,0.000008431746,0.00037158252],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99840117,0.000050913775,0.00051688775,0.00019577259,0.00052914844,0.00030609724],"domain_scores_gemma":[0.99907017,0.00014470163,0.0003038378,0.00018560572,0.000085442785,0.0002102509],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012383783,0.00010452278,0.0003207568,0.0005022641,0.000038821752,0.000017347367,0.00020958632,0.00003330914,0.000020404208],"category_scores_gemma":[0.000090851674,0.0000829972,0.00006578027,0.001155831,0.0003038656,0.00022215785,0.000057543763,0.00021520925,0.000011613112],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00061836094,0.00028270754,0.19527514,0.00015572857,0.000006859813,0.0026270426,0.0023488253,0.0006117973,0.7978295,0.000023689396,0.00007923305,0.00014109786],"study_design_scores_gemma":[0.004149546,0.0004046435,0.6105917,0.0001960896,0.000028533097,0.00006642953,0.0006050208,0.0011050792,0.3825054,0.00023164946,0.000029772298,0.00008610822],"about_ca_topic_score_codex":0.000055347304,"about_ca_topic_score_gemma":0.000013137707,"teacher_disagreement_score":0.41532412,"about_ca_system_score_codex":0.000064661115,"about_ca_system_score_gemma":0.00034607778,"threshold_uncertainty_score":0.33845276},"labels":[],"label_agreement":null},{"id":"W4387062046","doi":"10.1249/01.mss.0000980756.89099.87","title":"Characterizing Autophagic And Apoptotic Responses To Cold Stress In Healthy, Young And Older Men","year":2023,"lang":"en","type":"article","venue":"Medicine & Science in Sports & Exercise","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Apoptosis; Autophagy; Cold-shock domain; Western blot; Cold stress; Andrology; Medicine; Peripheral blood mononuclear cell; Oxidative stress; Analysis of variance; TUNEL assay; Internal medicine; Endocrinology; Biology; Chemistry; Physiology; In vitro; Biochemistry","score_opus":0.018558690342498917,"score_gpt":0.3177992149055745,"score_spread":0.2992405245630756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387062046","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937961,0.00045392834,0.0000018681012,0.0040954268,0.00027737423,0.0009326724,0.0000041473227,0.00008723747,0.00035126237],"genre_scores_gemma":[0.9960406,0.0017858155,0.000054133994,0.0011742545,0.000092926726,0.00008305536,0.0000070905585,0.000020220743,0.00074190437],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9975114,0.00003136317,0.00046846925,0.0006438281,0.0007226382,0.00062230986],"domain_scores_gemma":[0.99888283,0.000084995365,0.000084749256,0.0003569139,0.00005727149,0.0005332456],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017719317,0.00021035945,0.00054545177,0.001134483,0.00014230427,0.000027989821,0.00016040995,0.000060476123,0.00009419118],"category_scores_gemma":[0.0002113542,0.00016885268,0.000018669027,0.0020433727,0.0005845317,0.00024994477,0.000112067784,0.00020897818,0.000009541824],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005609122,0.000104097424,0.9627324,0.0001403988,6.2034314e-7,0.001324579,0.008622767,0.0000025573793,0.0078297695,0.000016726784,0.00015343472,0.018511744],"study_design_scores_gemma":[0.001660934,0.00028594246,0.99264216,0.0016565588,0.000021608292,0.000044071756,0.0025253561,0.00039575854,0.0004085446,0.000066775436,0.00013890314,0.00015340297],"about_ca_topic_score_codex":0.0003527364,"about_ca_topic_score_gemma":0.000028727914,"teacher_disagreement_score":0.02990975,"about_ca_system_score_codex":0.00010571629,"about_ca_system_score_gemma":0.00026322776,"threshold_uncertainty_score":0.6885612},"labels":[],"label_agreement":null},{"id":"W4387108150","doi":"10.1016/j.msard.2023.105029","title":"The role of autophagy protein Atg5 in multiple sclerosis","year":2023,"lang":"en","type":"review","venue":"Multiple Sclerosis and Related Disorders","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; Ontario Brain Institute; University of Calgary","funders":"","keywords":"Autophagy; ATG5; Multiple sclerosis; Biology; Cell biology; Immunology; Genetics; Apoptosis","score_opus":0.05367112339667342,"score_gpt":0.27502037442032273,"score_spread":0.22134925102364933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387108150","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.013401794,0.9824857,0.0000011658085,0.00008399214,0.00020120222,0.003183566,0.00009790859,0.00016392997,0.00038071806],"genre_scores_gemma":[0.046678115,0.9516176,0.000034667133,0.00001622931,0.000040332015,0.00068613753,0.0001378027,0.00016883627,0.00062029425],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966123,0.000272582,0.0013428167,0.00071383215,0.00041939918,0.00063907454],"domain_scores_gemma":[0.99779046,0.0006402251,0.0005596003,0.0007304864,0.000053666765,0.00022558168],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000506966,0.0006329142,0.0018466857,0.0003668119,0.0003264712,0.000047489462,0.00032991168,0.00077555777,0.000051904866],"category_scores_gemma":[0.0003759269,0.00041119417,0.0008207776,0.0010925136,0.00045135274,0.00007896613,0.00016842637,0.00083172723,0.00007966844],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011817503,0.00036386802,0.0004946659,0.003189692,0.0007901181,0.000006360728,0.000269275,0.0000071227564,0.00019016863,0.00012919541,0.00006105552,0.9943803],"study_design_scores_gemma":[0.013265335,0.0006431934,0.019311612,0.09248642,0.0025325057,0.000015990763,0.0014001972,0.002724158,0.00041204068,0.0018031102,0.8636355,0.0017699522],"about_ca_topic_score_codex":0.00048734978,"about_ca_topic_score_gemma":0.00021723432,"teacher_disagreement_score":0.99261034,"about_ca_system_score_codex":0.0000937425,"about_ca_system_score_gemma":0.00023929961,"threshold_uncertainty_score":0.999834},"labels":[],"label_agreement":null},{"id":"W4387300036","doi":"10.21203/rs.3.rs-3352490/v1","title":"Loss of ULK1 impairs autophagy activation, spheroid viability, and tumor progression in epithelial ovarian cancer","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"London Health Sciences Foundation; Cancer Research Society","keywords":"Autophagy; Viability assay; Cancer research; Ovarian cancer; Carboplatin; Metastasis; Biology; Cancer; Apoptosis; Medicine; Cisplatin; Internal medicine; Chemotherapy; Biochemistry","score_opus":0.057043586495745494,"score_gpt":0.4350697194876362,"score_spread":0.3780261329918907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387300036","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99364513,0.0011470193,0.000027371265,0.0018400988,0.00017788254,0.0026293613,0.00022021147,0.00010458663,0.00020832299],"genre_scores_gemma":[0.99714977,0.00078642945,0.0001907074,0.000027460925,0.0003871139,0.0007526466,0.000117830685,0.00007449393,0.0005135765],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99637836,0.00047514003,0.0005424976,0.0007534981,0.0012609932,0.00058953813],"domain_scores_gemma":[0.99780095,0.00035299157,0.00016683347,0.0007863878,0.0005977631,0.00029509104],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016976222,0.0002759872,0.0006518882,0.0005050878,0.00010097036,0.000041278912,0.0002638447,0.00033685908,0.00052548037],"category_scores_gemma":[0.0006508504,0.00023029583,0.00015104655,0.000655285,0.00042778993,0.000079635094,0.00072967913,0.0013843538,0.000018780822],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0090079075,0.004707342,0.83293927,0.032946505,0.0008772286,0.0018500284,0.0072536846,0.000496998,0.04762595,0.0012989633,0.0026414571,0.05835467],"study_design_scores_gemma":[0.0030069512,0.0006909794,0.9094336,0.0069186874,0.000037179678,0.000008444325,0.0005084995,0.0011686438,0.06546754,0.011949633,0.0005250273,0.00028480205],"about_ca_topic_score_codex":0.0022616354,"about_ca_topic_score_gemma":0.00014837766,"teacher_disagreement_score":0.07649436,"about_ca_system_score_codex":0.00040946144,"about_ca_system_score_gemma":0.0016665298,"threshold_uncertainty_score":0.9391191},"labels":[],"label_agreement":null},{"id":"W4387306433","doi":"10.1016/j.nmd.2023.07.040","title":"P59 Generation and characterization of a novel XMEA mouse model and pharmacological evaluation of autophagy antagonists","year":2023,"lang":"en","type":"article","venue":"Neuromuscular Disorders","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Amgen (Canada); University of Toronto; Hospital for Sick Children","funders":"","keywords":"Autophagy; Characterization (materials science); Pharmacology; Chemistry; Biology; Nanotechnology; Materials science; Biochemistry; Apoptosis","score_opus":0.057447313274947065,"score_gpt":0.32871219398816953,"score_spread":0.27126488071322247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387306433","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980975,0.00015130975,0.0008137472,0.0002585161,0.00004874853,0.000517102,0.00003145857,0.00004297414,0.00003869185],"genre_scores_gemma":[0.99813277,0.0013561278,0.00009002356,0.0001550341,0.00002500337,0.000034806217,0.00015679988,0.000016200089,0.000033236916],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.999016,0.000060117123,0.0002013737,0.00020946345,0.00041136597,0.000101701924],"domain_scores_gemma":[0.99959904,0.000013547431,0.000093006085,0.000117354844,0.000119806486,0.00005726185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002971955,0.000098639444,0.00018131573,0.00010658879,0.00004238182,0.000006398095,0.00003055552,0.00006217354,0.000019595482],"category_scores_gemma":[0.000056746485,0.00009012523,0.000049152382,0.00016495705,0.00008154604,0.0000814277,0.000024413484,0.000055709705,6.8762665e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006805914,0.00021159863,0.0006999142,0.00006643631,0.00005433173,8.1596e-7,0.00021692688,0.0011816967,0.9893617,0.00010518791,0.00001330134,0.008020041],"study_design_scores_gemma":[0.0032024356,0.00015893498,0.10385959,0.000010754485,0.00028056616,0.0000024601145,0.000019276626,0.77666914,0.11560293,0.00008936085,0.000028553273,0.0000759771],"about_ca_topic_score_codex":0.000005236975,"about_ca_topic_score_gemma":0.0000017948823,"teacher_disagreement_score":0.87375873,"about_ca_system_score_codex":0.000012007169,"about_ca_system_score_gemma":0.00007266773,"threshold_uncertainty_score":0.36752},"labels":[],"label_agreement":null},{"id":"W4387308096","doi":"10.1101/2023.10.02.560389","title":"Identification and structural characterization of small-molecule inhibitors of PINK1","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Argonne National Laboratory; Fonds de Recherche du Québec - Santé; Parkinson Canada; Canadian Institutes of Health Research; Office of Science; McGill University; U.S. Department of Energy","keywords":"PINK1; Parkin; Cell biology; Autophosphorylation; Ubiquitin ligase; Kinase; Biology; Ubiquitin; Biochemistry; Mitochondrion; Protein kinase A; Mitophagy; Chemistry; Autophagy; Medicine","score_opus":0.015046684160772796,"score_gpt":0.23947970266098312,"score_spread":0.22443301850021033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387308096","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976632,0.00038976537,0.00031278614,0.0001139445,0.0005442582,0.00062547455,0.00021629811,0.0001335257,7.749842e-7],"genre_scores_gemma":[0.9990948,0.00037940996,0.00015256573,0.000037528374,0.00020105092,0.000048702863,0.0000043726955,0.00007395375,0.000007611693],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99848086,0.000052950185,0.0005877643,0.00044672962,0.00025609997,0.00017558891],"domain_scores_gemma":[0.9981682,0.000017828135,0.0006334751,0.0006503727,0.00040393387,0.00012621986],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021386475,0.00024841828,0.0004755175,0.00026519797,0.000040222414,0.000026927932,0.00013632052,0.00028893867,0.00001980149],"category_scores_gemma":[0.0000688038,0.00025725004,0.00010812899,0.00030478393,0.00012516546,0.00006291886,0.00014403273,0.00023236808,0.0000060360226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050150215,0.00004326858,0.015341631,0.0011302137,0.00017222816,0.000011184075,0.000019501398,0.0000016909704,0.9830689,0.0001475074,0.000008515982,0.000005196697],"study_design_scores_gemma":[0.0002870589,0.000030771065,0.44849178,0.00026275156,0.00012263311,7.167688e-9,0.0000019208485,0.00014820187,0.55052805,0.0000022381132,0.000010616602,0.00011396359],"about_ca_topic_score_codex":0.000023372993,"about_ca_topic_score_gemma":4.861043e-7,"teacher_disagreement_score":0.43315017,"about_ca_system_score_codex":0.00005149501,"about_ca_system_score_gemma":0.00028284133,"threshold_uncertainty_score":0.99998796},"labels":[],"label_agreement":null},{"id":"W4387405271","doi":"10.1101/2023.10.05.560930","title":"Targeting LC3/GABARAP for degrader development and autophagy modulation","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Genentech; Deutsche Forschungsgemeinschaft; Deutschen Konsortium für Translationale Krebsforschung; Ontario Genomics Institute; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Ontario Genomics; Genome Canada; Bundesministerium für Bildung und Forschung; Diamond Light Source; McGill University; Bayer; Pfizer; Deutsches Krebsforschungszentrum; Bristol-Myers Squibb","keywords":"Druggability; Autophagosome; Autophagy; ULK1; In silico; Computational biology; Docking (animal); Small molecule; Chemistry; Drug discovery; Biology; Cell biology; Biochemistry; Kinase; Medicine","score_opus":0.031244216897104923,"score_gpt":0.26365844906419506,"score_spread":0.23241423216709012,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387405271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98418325,0.0022058627,0.009835439,0.0003125487,0.0009256477,0.0016644977,0.000103372615,0.00076659274,0.0000027883186],"genre_scores_gemma":[0.9732111,0.00025843066,0.024654582,0.00030013802,0.0006558574,0.00066350086,0.000004914473,0.00020557169,0.000045886052],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9975553,0.000046495254,0.000584485,0.0009327098,0.00035645065,0.0005245664],"domain_scores_gemma":[0.9983274,0.00008639459,0.00029647799,0.00061349606,0.00034759042,0.00032865762],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050759624,0.0005019642,0.0006138086,0.0002930603,0.0002344519,0.00010312591,0.0001720055,0.00049514894,0.000025347561],"category_scores_gemma":[0.00020367667,0.0005138951,0.00014927606,0.00024769668,0.000074168165,0.00009218905,0.00020790145,0.0004175283,0.000044137123],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053770706,0.0006598803,0.025358014,0.006129955,0.0023918375,0.00033285993,0.0002023574,0.0005037961,0.9586683,0.002304005,0.0027516405,0.00015964553],"study_design_scores_gemma":[0.0025976896,0.00010877614,0.6318388,0.0008565066,0.00040174933,4.329251e-8,0.000010750549,0.011050763,0.34197807,0.00003087627,0.010010186,0.00111579],"about_ca_topic_score_codex":0.00000939706,"about_ca_topic_score_gemma":3.4606833e-7,"teacher_disagreement_score":0.6166902,"about_ca_system_score_codex":0.00022138302,"about_ca_system_score_gemma":0.000723661,"threshold_uncertainty_score":0.99973124},"labels":[],"label_agreement":null},{"id":"W4387534067","doi":"10.1016/j.mitoco.2023.10.001","title":"Role of TFEB and TFE3 in mediating lysosomal and mitochondrial adaptations to contractile activity in skeletal muscle myotubes","year":2023,"lang":"en","type":"article","venue":"Mitochondrial Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"TFEB; Mitophagy; Cell biology; Myogenesis; Biology; Transcription factor; NRF1; Mitochondrion; Skeletal muscle; Mitochondrial biogenesis; Autophagy; Myocyte; Biochemistry; Endocrinology; Gene","score_opus":0.022603085231574407,"score_gpt":0.3063985252953721,"score_spread":0.2837954400637977,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387534067","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99548715,0.00078485603,0.000028508337,0.0019693,0.00012474561,0.0007879466,0.00006638718,0.000055663386,0.00069546734],"genre_scores_gemma":[0.9962898,0.0004841799,0.0026456884,0.000075906886,0.00013326421,0.00022629174,0.00006870206,0.000020880549,0.000055269942],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99879634,0.00017944638,0.00036679397,0.00023980545,0.00018331454,0.00023430651],"domain_scores_gemma":[0.9982857,0.0007205605,0.00009152732,0.0006879743,0.000064505446,0.00014974095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013373786,0.00013817604,0.00034088906,0.0003713337,0.00012964632,0.000020386296,0.0002043416,0.00010892364,0.000020833191],"category_scores_gemma":[0.0005079714,0.00014637836,0.00005561705,0.0006651031,0.00015906377,0.0001762296,0.00021060133,0.00029426027,0.0000107197],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022842859,0.0005085106,0.008148919,0.000031459287,0.00005178592,0.00000797833,0.005549939,0.000045001103,0.9535143,0.0016068625,0.00008004041,0.0302268],"study_design_scores_gemma":[0.004237868,0.00022595705,0.9746769,0.0001593832,0.00006746913,0.000006549212,0.0027126267,0.004857547,0.008653843,0.001431356,0.0027428144,0.00022766337],"about_ca_topic_score_codex":0.0007937026,"about_ca_topic_score_gemma":0.0022116366,"teacher_disagreement_score":0.966528,"about_ca_system_score_codex":0.000043423963,"about_ca_system_score_gemma":0.00013349002,"threshold_uncertainty_score":0.5969136},"labels":[],"label_agreement":null},{"id":"W4387538480","doi":"10.1101/2023.10.10.561758","title":"mTOR inhibits autophagy to facilitate cell swelling and rapid wound repair","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Ted Rogers Centre for Heart Research; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Autophagy; mTORC1; Wound healing; Cell biology; PI3K/AKT/mTOR pathway; Embryonic stem cell; Cell growth; Cell; Biology; Chemistry; Cancer research; Signal transduction; Apoptosis; Immunology; Biochemistry","score_opus":0.03662572391916641,"score_gpt":0.24590851912054743,"score_spread":0.20928279520138102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387538480","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98772764,0.0057777334,0.00056138047,0.00043137989,0.0013629991,0.0017588595,0.00035087395,0.0019901106,0.000039012393],"genre_scores_gemma":[0.99031335,0.0015868118,0.0051250067,0.0011734633,0.0008245071,0.00035505492,0.0000016062547,0.00029480786,0.00032539867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99602604,0.00012260998,0.0007786859,0.001644662,0.00059140316,0.0008366094],"domain_scores_gemma":[0.9965094,0.000116178235,0.0002767186,0.001697047,0.0004078,0.000992877],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00075913477,0.00079929404,0.0010175006,0.00053876004,0.00021580202,0.00015431366,0.00031169318,0.0006702005,0.00013277655],"category_scores_gemma":[0.0002216594,0.00083598535,0.0003531329,0.0006350015,0.00014158778,0.000119255485,0.0005690059,0.0009990787,0.00063321844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00057446404,0.0005836836,0.0050095287,0.0046984754,0.0010222392,0.0014314549,0.00025288796,0.00014905211,0.9802227,0.0002635941,0.0057689934,0.0000229039],"study_design_scores_gemma":[0.003064847,0.0005761482,0.16546546,0.0018153526,0.00079038594,1.4141611e-7,0.000025154852,0.0010341624,0.77807724,0.000019372954,0.04710118,0.002030563],"about_ca_topic_score_codex":0.000065531436,"about_ca_topic_score_gemma":0.0000013923274,"teacher_disagreement_score":0.20214549,"about_ca_system_score_codex":0.0002755423,"about_ca_system_score_gemma":0.0007247589,"threshold_uncertainty_score":0.9994091},"labels":[],"label_agreement":null},{"id":"W4387541727","doi":"10.1101/2023.10.11.561600","title":"Reduced S-acylation of SQSTM1/p62 in Huntington disease is associated with impaired autophagy","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; Child and Family Research Institute; University of British Columbia; University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Royal Society","keywords":"Autophagy; Sequestosome 1; Cell biology; Acylation; Lysosome; Flux (metallurgy); Chemistry; Biology; Biochemistry; Apoptosis; Enzyme","score_opus":0.02035323343795675,"score_gpt":0.2525664808069156,"score_spread":0.23221324736895887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387541727","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99619997,0.0006018752,0.000051996612,0.00047149727,0.0004353288,0.0012829063,0.00034113126,0.00060536084,0.000009908537],"genre_scores_gemma":[0.99841565,0.000188643,0.00033636336,0.00033571234,0.00022137092,0.00023212691,0.0000071625736,0.0002244587,0.000038499114],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.996745,0.0001537434,0.00082820153,0.0009934824,0.0006962177,0.00058334717],"domain_scores_gemma":[0.9968222,0.000099332385,0.0007762322,0.0013189272,0.0005448457,0.00043849042],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00057826535,0.00058443553,0.0010213999,0.0005899379,0.00007940571,0.00005539054,0.00030842362,0.0005126377,0.00008508821],"category_scores_gemma":[0.0005404305,0.0005775262,0.00025768616,0.0011039444,0.00014974498,0.00013215558,0.00020119183,0.00068539515,0.00003608783],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021818972,0.0021541698,0.22522008,0.0025912256,0.0019023032,0.00096231524,0.00017712695,0.00025187785,0.7631972,0.00029763486,0.0010530659,0.000011135186],"study_design_scores_gemma":[0.0020700328,0.00012210119,0.77949965,0.0020668337,0.00038464283,5.5952403e-9,0.000004054674,0.0009536603,0.21437144,0.000009460472,0.00005860728,0.00045953543],"about_ca_topic_score_codex":0.00010687327,"about_ca_topic_score_gemma":0.0000037491504,"teacher_disagreement_score":0.5542795,"about_ca_system_score_codex":0.00044172246,"about_ca_system_score_gemma":0.0016442514,"threshold_uncertainty_score":0.99966764},"labels":[],"label_agreement":null},{"id":"W4387784119","doi":"10.1016/j.celrep.2023.113291","title":"Mitochondria-lysosome-related organelles mediate mitochondrial clearance during cellular dedifferentiation","year":2023,"lang":"en","type":"article","venue":"Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Institute on Alcohol Abuse and Alcoholism; National Institute on Aging; University of Kansas Medical Center; National Institutes of Health; Universidade de Macau","keywords":"Mitophagy; Lysosome; Cell biology; Autophagy; Mitochondrion; TFEB; Biology; Organelle; mitochondrial fusion; Biochemistry; Mitochondrial DNA; Gene","score_opus":0.007407516956473103,"score_gpt":0.2294744094468261,"score_spread":0.222066892490353,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387784119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934147,0.00086398434,0.000040868286,0.00023433872,0.0025349804,0.00057348714,0.0000034071948,0.00059025007,0.0017439836],"genre_scores_gemma":[0.9836617,0.00041575122,0.00006638253,0.00007275575,0.00078078394,0.00004247745,0.00026248093,0.00007933035,0.014618315],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977632,0.000048900794,0.00067111757,0.00055578595,0.0005185647,0.00044241847],"domain_scores_gemma":[0.99861497,0.000042480537,0.00032206668,0.0006484306,0.00009684744,0.00027519456],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000112446636,0.0002538296,0.00040187832,0.00022575744,0.00017116558,0.00003165996,0.00008468639,0.00022209989,0.0009574676],"category_scores_gemma":[0.00010482523,0.00023462661,0.00022594751,0.0005821755,0.00006456756,0.00010603448,0.000054059823,0.00025439356,0.0007857819],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019364816,0.0001822885,0.004749303,0.00019695007,0.0001506072,0.0072722463,0.0006943831,0.00007490947,0.9826991,0.000013196751,0.0035174147,0.00025593324],"study_design_scores_gemma":[0.0029241107,0.00010748386,0.104065046,0.00016632532,0.0003442991,0.0002983969,0.0001700609,0.00034539233,0.8865738,0.0012313381,0.0033560335,0.00041770202],"about_ca_topic_score_codex":0.000009183122,"about_ca_topic_score_gemma":0.0000011866844,"teacher_disagreement_score":0.09931575,"about_ca_system_score_codex":0.000054168377,"about_ca_system_score_gemma":0.00012423373,"threshold_uncertainty_score":0.99999225},"labels":[],"label_agreement":null},{"id":"W4387933514","doi":"10.1016/j.envpol.2023.122811","title":"MicroRNA-217-5p triggers dopaminergic neuronal degeneration via autophagy activation under Atrazine exposure","year":2023,"lang":"en","type":"article","venue":"Environmental Pollution","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China; St. Thomas University","keywords":"Autophagy; Epigenetics; microRNA; Dopaminergic; Cell biology; Biology; Gene expression; Histone; Regulation of gene expression; Gene silencing; Apoptosis; Gene; Genetics; Neuroscience; Dopamine","score_opus":0.01165557838255872,"score_gpt":0.23710871545898382,"score_spread":0.22545313707642511,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387933514","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99563235,0.000250518,0.0017640066,0.0012693444,0.0002906293,0.00036925482,0.000032828495,0.00019987424,0.0001911961],"genre_scores_gemma":[0.9943944,0.00019329863,0.00010681976,0.0011834165,0.00043028066,0.000036303696,0.0009956372,0.000042490534,0.0026173217],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998683,0.00006447589,0.00026743914,0.00033975413,0.0003601648,0.00028519766],"domain_scores_gemma":[0.999504,0.00001839819,0.00009812892,0.00023550417,0.0000049289083,0.00013901295],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010736393,0.00020807408,0.00017936227,0.00016170937,0.00017440994,0.000015688092,0.000060337516,0.00012918322,0.00058123627],"category_scores_gemma":[0.00000690342,0.00020114888,0.00013196691,0.00023375497,0.0000912969,0.00021356186,0.000028752213,0.00015239281,0.0006264023],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022976934,0.00020281959,0.000726663,0.000011930549,0.00005445284,0.000020610896,0.00007410559,0.0014391652,0.98816675,0.00012191863,0.0010254675,0.007926318],"study_design_scores_gemma":[0.002256444,0.00033427976,0.5227038,0.000017002465,0.00007433868,0.00003325441,0.00008471164,0.0019057966,0.4699232,0.0002922354,0.0021791218,0.00019578509],"about_ca_topic_score_codex":0.000009929037,"about_ca_topic_score_gemma":0.0000012515785,"teacher_disagreement_score":0.5219771,"about_ca_system_score_codex":0.00029296236,"about_ca_system_score_gemma":0.0000327956,"threshold_uncertainty_score":0.8202613},"labels":[],"label_agreement":null},{"id":"W4388048619","doi":"10.3390/ijms242115788","title":"Therapeutic Effects of Mesenchymal Stromal Cells Require Mitochondrial Transfer and Quality Control","year":2023,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Mitophagy; Mesenchymal stem cell; DNM1L; Cell biology; Biology; Mitochondrial biogenesis; PINK1; mitochondrial fusion; Mitochondrial fission; Mitochondrion; Transplantation; Inflammation; Immunology; Autophagy; Medicine; Mitochondrial DNA; Apoptosis","score_opus":0.0520760694779428,"score_gpt":0.39926986849747637,"score_spread":0.34719379901953357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388048619","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.014541313,0.9809204,0.0021426436,0.00012411064,0.0017951537,0.00037017508,0.000033809112,0.000008369586,0.000064049826],"genre_scores_gemma":[0.050949562,0.9481695,0.00020286239,0.00016081175,0.00042925027,0.000007434623,0.0000033551917,0.000020487598,0.000056731496],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972621,0.00028233224,0.0008476063,0.00021424855,0.0012357155,0.00015796993],"domain_scores_gemma":[0.99850935,0.00050108565,0.0004754881,0.00011522969,0.00027213898,0.00012669513],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005811803,0.00020924267,0.0010805825,0.00035663912,0.0000343425,0.000046290457,0.0004970603,0.0001311714,0.000026794738],"category_scores_gemma":[0.00012435704,0.00013876757,0.0006839052,0.00019504272,0.00035647812,0.00013247223,0.000026977496,0.00025488017,0.0000035641144],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007542562,0.0006311068,0.000055339984,0.010624806,0.008694458,0.0033399032,0.00041605887,0.000020514664,0.047902208,0.007677123,0.00005852838,0.9198257],"study_design_scores_gemma":[0.06332291,0.024556126,0.0030503818,0.23335706,0.03279212,0.008047731,0.0008276487,0.0003402061,0.11337476,0.016548323,0.49931183,0.004470883],"about_ca_topic_score_codex":0.00000815114,"about_ca_topic_score_gemma":5.682439e-7,"teacher_disagreement_score":0.9153548,"about_ca_system_score_codex":0.00004176706,"about_ca_system_score_gemma":0.0006364127,"threshold_uncertainty_score":0.56587774},"labels":[],"label_agreement":null},{"id":"W4388133835","doi":"10.1080/15548627.2023.2276639","title":"CKLF induces microglial activation via triggering defective mitophagy and mitochondrial dysfunction","year":2023,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Mitophagy; PINK1; Cell biology; Autophagy; Biology; Microglia; Neuroinflammation; Lysosome; Parkin; Autophagosome; Mitochondrion; Proinflammatory cytokine; Inflammation; Immunology; Biochemistry; Apoptosis","score_opus":0.014359225753952235,"score_gpt":0.26995936568088824,"score_spread":0.25560013992693603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388133835","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99592364,0.0003540415,0.0006872606,0.00025920107,0.0011399629,0.00051992456,0.000008941334,0.00045201715,0.00065498904],"genre_scores_gemma":[0.99651766,0.00012442612,0.00018814675,0.0003783226,0.0011918372,0.000086001615,0.00007982915,0.000046239522,0.0013875372],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986069,0.0000630176,0.00026672863,0.00043976607,0.00027772703,0.00034583002],"domain_scores_gemma":[0.9992455,0.00013237425,0.000103552986,0.0002494975,0.00010021798,0.00016881098],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011923908,0.00022931158,0.0003218476,0.00028427262,0.00019372853,0.000040508625,0.00006670296,0.00020485956,0.00015787868],"category_scores_gemma":[0.00011723827,0.00021385815,0.000113771195,0.00058181206,0.00008313036,0.00024472264,0.00005116384,0.0002335321,0.00021460468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071668386,0.00012256083,0.00032328308,0.00006282818,0.00021113029,0.00011648275,0.0006659418,0.000009170095,0.9435547,0.00017345221,0.0009392391,0.05310451],"study_design_scores_gemma":[0.0045449766,0.00045920617,0.11011592,0.000074012234,0.00012382037,0.00009000346,0.00016657326,0.0006713458,0.8786806,0.0015932937,0.0032028991,0.0002773453],"about_ca_topic_score_codex":0.00007694262,"about_ca_topic_score_gemma":0.000002667711,"teacher_disagreement_score":0.109792635,"about_ca_system_score_codex":0.000090716385,"about_ca_system_score_gemma":0.00010269024,"threshold_uncertainty_score":0.87208825},"labels":[],"label_agreement":null},{"id":"W4388304750","doi":"10.3390/cancers15215280","title":"Sorafenib Resistance Contributed by IL7 and MAL2 in Hepatocellular Carcinoma Can Be Overcome by Autophagy-Inducing Stapled Peptides","year":2023,"lang":"en","type":"article","venue":"Cancers","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"National Natural Science Foundation of China","keywords":"Sorafenib; Cancer research; Autophagy; PI3K/AKT/mTOR pathway; Downregulation and upregulation; Protein kinase B; Medicine; Hepatocellular carcinoma; Biology; Signal transduction; Cell biology; Apoptosis; Gene; Biochemistry","score_opus":0.015338307034163164,"score_gpt":0.25904769230168595,"score_spread":0.24370938526752278,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388304750","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987888,0.009166577,0.0000119015285,0.0013005125,0.00013621707,0.0005157755,0.0005473332,0.00015867368,0.00027505122],"genre_scores_gemma":[0.9927599,0.00062704645,0.000018424496,0.0012718139,0.00007115777,0.000094834235,0.00037553566,0.000047588113,0.0047337124],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99840057,0.00005991112,0.000304037,0.00045614495,0.00025047094,0.0005288474],"domain_scores_gemma":[0.99916047,0.00008731691,0.000093519644,0.000327922,0.000056213095,0.00027457738],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021239503,0.00023603928,0.000455133,0.00013323523,0.00010933895,0.000027630833,0.000108608954,0.0001279393,0.00011668125],"category_scores_gemma":[0.00006698784,0.0002379578,0.0000705335,0.00051829865,0.0001275169,0.00008707897,0.000034141376,0.0002311783,0.000008552735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002109318,0.000111620284,0.31458396,0.0007218133,0.0004675239,0.0021896542,0.0043790457,0.00008467868,0.40344766,0.0005200047,0.26994875,0.0014359811],"study_design_scores_gemma":[0.03745799,0.00076132076,0.34385502,0.0013268084,0.00046789407,0.000037576174,0.0049363174,0.018094547,0.4307565,0.0013840484,0.15869504,0.002226915],"about_ca_topic_score_codex":0.0018397364,"about_ca_topic_score_gemma":0.00029881566,"teacher_disagreement_score":0.11125369,"about_ca_system_score_codex":0.0010265884,"about_ca_system_score_gemma":0.00051901996,"threshold_uncertainty_score":0.9703638},"labels":[],"label_agreement":null},{"id":"W4388511476","doi":"10.1016/j.bbadis.2023.166824","title":"Metastatic outgrowth via the two-way interplay of autophagy and metabolism","year":2023,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"Ministero della Salute; European Commission; Agencia Estatal de Investigación; University of Manitoba; Ministerio de Ciencia e Innovación; CancerCare Manitoba Foundation","keywords":"Anoikis; Autophagy; Metastasis; Extracellular matrix; Context (archaeology); Stromal cell; Cell biology; Biology; Cancer cell; Cancer research; Cancer; Apoptosis; Biochemistry; Genetics","score_opus":0.024093004413932376,"score_gpt":0.34306974281539454,"score_spread":0.3189767384014622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388511476","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.09604816,0.8995868,0.00008772838,0.00047547903,0.00020028287,0.0021024426,0.0012864231,0.000116932955,0.000095782685],"genre_scores_gemma":[0.19640256,0.80155104,0.0002346063,0.0004795862,0.00013947122,0.0002701229,0.00057596876,0.00024923738,0.000097401884],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99577785,0.000671405,0.0012986079,0.00091571826,0.0008324323,0.00050400203],"domain_scores_gemma":[0.9959959,0.00037144485,0.0011266243,0.0017185698,0.00017717064,0.0006103107],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036971108,0.00096137426,0.0030825525,0.0004932027,0.000086897555,0.000046430887,0.000744211,0.00017451211,0.00005447151],"category_scores_gemma":[0.0002324726,0.00063953124,0.0021793256,0.0009131811,0.00065385085,0.000098884346,0.00039870283,0.00048246706,0.000038214836],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003294083,0.009546323,0.000002989418,0.18635911,0.0593066,0.0018749513,0.0015946163,0.000005508102,0.19573487,0.014016315,0.0023727303,0.5258919],"study_design_scores_gemma":[0.014906106,0.0019764174,0.003804862,0.06521559,0.21743767,0.0001713175,0.00031934556,0.0005445767,0.6052731,0.0096292,0.07436523,0.006356557],"about_ca_topic_score_codex":0.000037987782,"about_ca_topic_score_gemma":7.377926e-7,"teacher_disagreement_score":0.51953536,"about_ca_system_score_codex":0.000043133234,"about_ca_system_score_gemma":0.00071796565,"threshold_uncertainty_score":0.9996056},"labels":[],"label_agreement":null},{"id":"W4388637591","doi":"10.1152/ajpregu.00163.2023","title":"The intensity-dependent effects of exercise and superimposing environmental heat stress on autophagy in peripheral blood mononuclear cells from older men","year":2023,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Peripheral blood mononuclear cell; Autophagy; Heat stress; Medicine; Shock (circulatory); Intensity (physics); Heat shock protein; Stimulation; Peripheral; Heat shock; Hsp70; Peripheral blood; Exercise intensity; Internal medicine; Endocrinology; Physiology; Apoptosis; Blood pressure; Biology; Heart rate; Animal science; Biochemistry; In vitro","score_opus":0.008011285174543248,"score_gpt":0.2525347301331482,"score_spread":0.24452344495860495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388637591","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975216,0.0018738033,0.000004809506,0.000090464535,0.00012854338,0.00031656894,0.000027890954,0.00001169061,0.00002464343],"genre_scores_gemma":[0.9979089,0.0016940809,0.00005258418,0.00016355491,0.00009611873,0.000016726583,0.0000150674405,0.000018851084,0.00003411716],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99824244,0.00042143068,0.00047959614,0.00036597313,0.00018448956,0.00030610224],"domain_scores_gemma":[0.9986531,0.00055044034,0.00033330728,0.00024376834,0.00007137834,0.00014797697],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011989039,0.00033117336,0.0012425741,0.00015025753,0.00013843196,0.000011213477,0.00016303292,0.000075658005,0.000027804703],"category_scores_gemma":[0.000011818449,0.00020337969,0.00016575864,0.0001549939,0.001758826,0.00008967283,0.000088396,0.00045754315,0.000004325512],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0032774752,0.00044982697,0.0014980449,0.00002473777,0.00060593785,0.000030790427,0.006133075,0.00017066803,0.98619545,0.00010607443,0.00011107676,0.0013968591],"study_design_scores_gemma":[0.0018744662,0.0032215756,0.5601583,0.00032241753,0.00012371929,0.000011246209,0.010855421,0.0005453179,0.4221286,0.00061353383,0.000009626489,0.00013578079],"about_ca_topic_score_codex":0.000104687395,"about_ca_topic_score_gemma":0.0000048732736,"teacher_disagreement_score":0.5640668,"about_ca_system_score_codex":0.000055069075,"about_ca_system_score_gemma":0.000056170386,"threshold_uncertainty_score":0.82935834},"labels":[],"label_agreement":null},{"id":"W4388799915","doi":"10.14740/wjon1681","title":"Circadian Clock REV-ERBs Agonist SR9009 Induces Synergistic Antitumor Activity in Multiple Myeloma by Suppressing Glucose-Regulated Protein 78-Dependent Autophagy and Lipogenesis","year":2023,"lang":"en","type":"article","venue":"World Journal of Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Bortezomib; Unfolded protein response; ATG5; Autophagy; Cancer research; Viability assay; Gene knockdown; Downregulation and upregulation; Apoptosis; Cell biology; Medicine; Biology; Endoplasmic reticulum; Multiple myeloma; Internal medicine; Biochemistry","score_opus":0.02406516763259758,"score_gpt":0.3018110262846736,"score_spread":0.277745858652076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388799915","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99302083,0.0035751704,0.000024817133,0.002216083,0.00038303784,0.00043304125,0.000018795869,0.00005382465,0.00027437182],"genre_scores_gemma":[0.9975878,0.00041186364,0.0001967282,0.00024213394,0.0003122706,0.000021864022,0.000012936569,0.00004296022,0.0011714593],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978304,0.00033139272,0.0006831196,0.00031649775,0.00035236427,0.00048620751],"domain_scores_gemma":[0.9984712,0.0002677069,0.00054056244,0.00023642149,0.00011939325,0.00036469396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006975469,0.00025452944,0.00083520584,0.0007073701,0.00017164293,0.000043893488,0.00018972404,0.00019561601,0.00012814956],"category_scores_gemma":[0.00025228955,0.00022612982,0.00013928022,0.00069932546,0.00021630187,0.00018364059,0.00007214035,0.0005849077,0.00001779293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001571735,0.0006401874,0.0062001087,0.0001277701,0.00023413521,0.004794429,0.00031617345,0.000046960573,0.89371413,0.000043046388,0.0011466973,0.091164604],"study_design_scores_gemma":[0.0076278634,0.0012748146,0.4150841,0.0005922424,0.00022022234,0.0006237515,0.00015539522,0.0007762424,0.5623048,0.00027927224,0.0107344,0.00032688255],"about_ca_topic_score_codex":0.000116645184,"about_ca_topic_score_gemma":0.00024965545,"teacher_disagreement_score":0.408884,"about_ca_system_score_codex":0.00034561678,"about_ca_system_score_gemma":0.0005695114,"threshold_uncertainty_score":0.92213064},"labels":[],"label_agreement":null},{"id":"W4389017312","doi":"10.1096/fasebj.31.1_supplement.839.17","title":"Regulation of Autophagy during Chronic Contractile Activity‐Induced Muscle Adaptations","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"York University","funders":"","keywords":"Autophagy; Skeletal muscle; TFEB; Mitochondrial biogenesis; Downregulation and upregulation; Biology; Mitochondrion; Cell biology; Internal medicine; Endocrinology; Lysosome; Regulator; Medicine; Biochemistry; Apoptosis; Gene","score_opus":0.03116878841995501,"score_gpt":0.3050606948964803,"score_spread":0.2738919064765253,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389017312","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968639,0.0002540032,0.00017452435,0.00094867084,0.00023601964,0.00015909757,0.0000046712494,0.000017382608,0.0013417413],"genre_scores_gemma":[0.9985528,0.00010265641,0.000037849164,0.000030049983,0.0005120744,0.0000045311594,0.0000015068068,0.00001401026,0.00074452185],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99929,0.00005117586,0.0001790955,0.000084700725,0.00023310752,0.00016191963],"domain_scores_gemma":[0.9988876,0.000048721624,0.00041376994,0.00045381067,0.00009663215,0.00009944024],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002108324,0.00008567353,0.00017044636,0.00005249905,0.0007596817,0.000051170497,0.00016832227,0.000048675676,0.00049773575],"category_scores_gemma":[0.00009132886,0.00005896268,0.00012907264,0.00003326675,0.00008654076,0.00026936873,0.000022250886,0.00026781592,0.000017516853],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001836854,0.00008604499,0.0003865365,0.000012414748,0.00010711694,0.000028884899,0.0002037444,0.00004953827,0.9825596,0.00015599457,0.000026309523,0.0162001],"study_design_scores_gemma":[0.001230336,0.00007648565,0.5616637,0.000055823348,0.00006957726,0.00010983535,0.000036623864,0.0006837667,0.43574676,0.00025474504,0.000037138827,0.00003522208],"about_ca_topic_score_codex":0.000029900697,"about_ca_topic_score_gemma":0.000008768205,"teacher_disagreement_score":0.56127715,"about_ca_system_score_codex":0.000092658425,"about_ca_system_score_gemma":0.00023338871,"threshold_uncertainty_score":0.5842934},"labels":[],"label_agreement":null},{"id":"W4389017331","doi":"10.1096/fasebj.31.1_supplement.839.18","title":"Parkin‐Mediated Mitophagy in Skeletal Muscle with Endurance Training","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mitophagy; Parkin; Mitochondrial biogenesis; Mitochondrion; Skeletal muscle; Endurance training; Chemistry; Endocrinology; Ubiquitin ligase; Cell biology; Internal medicine; Muscle atrophy; Biology; Ubiquitin; Biochemistry; Autophagy; Medicine; Apoptosis","score_opus":0.02891223660371078,"score_gpt":0.2830317156566753,"score_spread":0.2541194790529645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389017331","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99417305,0.00087807345,0.000058224578,0.0014691516,0.00020038491,0.0001414596,0.000004750313,0.000018962446,0.0030559308],"genre_scores_gemma":[0.9981699,0.00020504721,0.00011776357,0.0005906263,0.00056277093,0.000007406659,0.0000031459683,0.000020335545,0.00032298977],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990363,0.00005834407,0.0001972081,0.00012365278,0.00027590874,0.00030855424],"domain_scores_gemma":[0.99912757,0.000060546372,0.00020116333,0.0003968958,0.000042120115,0.00017173031],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003476758,0.00012828418,0.00022036672,0.00005726657,0.00043803934,0.00008186511,0.00028489236,0.00004855555,0.00026636076],"category_scores_gemma":[0.00008997662,0.000072054165,0.000084527965,0.000058249716,0.00019535335,0.00016225343,0.000020026038,0.0004968485,0.00003433927],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023843923,0.0009822551,0.14644365,0.00008408093,0.0011963382,0.013819141,0.015253999,0.00013027071,0.519888,0.00050219835,0.0015480785,0.29776764],"study_design_scores_gemma":[0.005021612,0.00020267903,0.97959477,0.00024565027,0.000067131536,0.0010862983,0.00061039976,0.0002521643,0.010069951,0.00035891467,0.002345602,0.00014484067],"about_ca_topic_score_codex":0.00001942798,"about_ca_topic_score_gemma":0.000018806548,"teacher_disagreement_score":0.8331511,"about_ca_system_score_codex":0.0000366185,"about_ca_system_score_gemma":0.00017829522,"threshold_uncertainty_score":0.33690888},"labels":[],"label_agreement":null},{"id":"W4389020765","doi":"10.1096/fasebj.31.1_supplement.470.8","title":"Initial Autophagic Protection Switches to Disruption of Autophagic Flux by Lysosomal Instability during Cadmium Stress Accrual in Renal NRK‐52E Cells","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Deutsche Forschungsgemeinschaft","keywords":"Autophagy; Viability assay; Cell biology; Programmed cell death; Bafilomycin; ATG5; Lysosome; Unfolded protein response; Apoptosis; LAMP1; Thapsigargin; Autophagosome; Endoplasmic reticulum; ATF6; Biology; Chemistry; Biochemistry","score_opus":0.024646055911536166,"score_gpt":0.3023289717236512,"score_spread":0.277682915812115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389020765","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99732447,0.00019545553,0.00019520373,0.0007178677,0.00045751303,0.0006892847,0.0000619101,0.000034726225,0.00032357138],"genre_scores_gemma":[0.99878764,0.000034465244,0.000056722227,0.00008731094,0.0006336805,0.000032032003,0.000010679716,0.000028160104,0.00032929183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979461,0.00018405904,0.0006216186,0.0002841405,0.00054849574,0.00041559717],"domain_scores_gemma":[0.9984262,0.00003720794,0.00048806367,0.000633947,0.00012685642,0.00028772638],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007090744,0.00024515245,0.00041135962,0.00016964161,0.0006054194,0.00011656663,0.00041047722,0.0001436974,0.00033004602],"category_scores_gemma":[0.00015698628,0.00017504452,0.00019215254,0.0001254701,0.00020477033,0.0003883205,0.00011477036,0.00073297834,0.000030680527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019246183,0.0004827974,0.008901396,0.000094109826,0.000099991434,0.00016742757,0.0012045738,0.00014549073,0.98283994,0.0000127729745,0.000044006432,0.004082875],"study_design_scores_gemma":[0.002371698,0.00033436317,0.28306097,0.0002124814,0.00006551225,0.00019102781,0.000236536,0.00020687422,0.71292686,0.00023296794,0.000029395424,0.00013129377],"about_ca_topic_score_codex":0.00018159437,"about_ca_topic_score_gemma":0.000042849795,"teacher_disagreement_score":0.27415958,"about_ca_system_score_codex":0.00024091035,"about_ca_system_score_gemma":0.00026518,"threshold_uncertainty_score":0.7138108},"labels":[],"label_agreement":null},{"id":"W4389021032","doi":"10.1096/fasebj.31.1_supplement.713.11","title":"Parkin Overexpression Attenuates Aging‐related Muscle Atrophy in Mice","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University Health Centre; Christie (Canada); Institut Universitaire de Gériatrie de Montréal; Université du Québec à Montréal","funders":"","keywords":"Parkin; Mitophagy; Sarcopenia; Muscle atrophy; Atrophy; Endocrinology; Internal medicine; Skeletal muscle; Mitochondrion; PINK1; Biology; Medicine; Anatomy; Autophagy; Cell biology; Parkinson's disease; Apoptosis; Disease; Genetics","score_opus":0.016839137866031872,"score_gpt":0.28748487011380075,"score_spread":0.2706457322477689,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389021032","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99300414,0.0011796685,0.0000120864415,0.0028666486,0.000231206,0.000114403774,0.0000033257963,0.00001809476,0.0025704207],"genre_scores_gemma":[0.99781156,0.0003319724,0.000055004384,0.00048219634,0.00034080466,0.000002771248,0.000003009262,0.000017986164,0.00095467013],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991012,0.00008225982,0.00022732063,0.00012133319,0.00022883754,0.00023902796],"domain_scores_gemma":[0.9991387,0.00004731299,0.00023027576,0.00040762918,0.00004045673,0.00013560135],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036473732,0.00011491404,0.00017597736,0.00006017125,0.000508061,0.00009131749,0.00030262122,0.00006182823,0.00047573392],"category_scores_gemma":[0.000079413134,0.000068404166,0.00012146486,0.000043546646,0.00011041576,0.00015446894,0.00005679267,0.0004960157,0.000098644974],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043445546,0.00023162941,0.038092174,0.0000200318,0.00017796474,0.0009318808,0.001268486,0.000041728297,0.93732107,0.00012781977,0.0024861987,0.018866587],"study_design_scores_gemma":[0.0064538075,0.00020599357,0.7841212,0.0010587077,0.00015695977,0.0006706063,0.0003250806,0.0007810289,0.19785999,0.005450956,0.0026857962,0.0002298464],"about_ca_topic_score_codex":0.00005039718,"about_ca_topic_score_gemma":0.0000025117297,"teacher_disagreement_score":0.7460291,"about_ca_system_score_codex":0.000045452416,"about_ca_system_score_gemma":0.0000672376,"threshold_uncertainty_score":0.5208953},"labels":[],"label_agreement":null},{"id":"W4389021454","doi":"10.1096/fasebj.31.1_supplement.707.10","title":"PGC‐1α – Dependent TFEB Expression and Activation with Exercise","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"York University","funders":"","keywords":"TFEB; NRF1; Mitophagy; Mitochondrial biogenesis; Cell biology; Transcription factor; Chemistry; Myogenesis; Biology; Autophagy; Mitochondrion; Myocyte; Biochemistry; Gene; Apoptosis","score_opus":0.017924041242863762,"score_gpt":0.27966084590935875,"score_spread":0.26173680466649496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389021454","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99680775,0.00040858594,0.0004690866,0.000983884,0.00007567021,0.00013360269,0.0000012335543,0.000011893127,0.0011082609],"genre_scores_gemma":[0.9980807,0.00046288493,0.00015244307,0.00020038086,0.00025908797,0.0000041686694,0.0000014200224,0.00001146685,0.00082747947],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99944824,0.000023481029,0.00009129318,0.00008318684,0.00023305524,0.00012072041],"domain_scores_gemma":[0.9993316,0.000018416167,0.00015984457,0.00031140185,0.000046497276,0.00013227505],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018097514,0.000081256156,0.00011426997,0.00002874519,0.00068879157,0.000109112974,0.000120259414,0.00003346588,0.00015117164],"category_scores_gemma":[0.000022921553,0.000039973816,0.00003155266,0.000013013684,0.00008041197,0.00019718538,0.000029840956,0.00021552567,0.000009095328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027500314,0.00015999819,0.01618383,0.000026622056,0.0001228946,0.00027821574,0.0010470471,0.000010598038,0.92943627,0.00007273626,0.0009121491,0.048999615],"study_design_scores_gemma":[0.0029367507,0.00019949257,0.12505093,0.00055543694,0.00013374323,0.0005761652,0.00032681038,0.000067786415,0.8691092,0.00076029997,0.00019523235,0.00008810437],"about_ca_topic_score_codex":0.000008127216,"about_ca_topic_score_gemma":8.68612e-7,"teacher_disagreement_score":0.1088671,"about_ca_system_score_codex":0.000019113111,"about_ca_system_score_gemma":0.000054482676,"threshold_uncertainty_score":0.5297697},"labels":[],"label_agreement":null},{"id":"W4389021625","doi":"10.1096/fasebj.31.1_supplement.934.23","title":"Role of autophagy in temozolomide‐induced apoptosis in Rhabdomyosarcoma cells","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autophagy; ATG5; Apoptosis; Programmed cell death; Temozolomide; Cancer research; Cell culture; BECN1; Viability assay; Population; MTT assay; Biology; Cell biology; Chemistry; Medicine; Biochemistry; Glioma","score_opus":0.018947028088187885,"score_gpt":0.2859892709844395,"score_spread":0.2670422428962516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389021625","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99577415,0.0005653615,0.000004425222,0.00075955177,0.00017745796,0.00019500488,0.0000038132675,0.000008024133,0.0025122322],"genre_scores_gemma":[0.99910957,0.0001893456,0.00008529695,0.00021624005,0.00018599334,0.000005600916,9.068346e-7,0.000016856673,0.00019021172],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99883807,0.00010513961,0.00039932443,0.00012270121,0.00025645786,0.0002783134],"domain_scores_gemma":[0.99889845,0.000068556656,0.00031176902,0.00055258384,0.00004468865,0.00012392944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006185769,0.00012967063,0.00034233928,0.00016196477,0.00016913746,0.00003881997,0.0004246953,0.00008309979,0.00023967389],"category_scores_gemma":[0.000080404985,0.00008579012,0.00014184706,0.000083259074,0.000108979424,0.00013375415,0.0000578481,0.00048498064,0.000026842885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039993928,0.00025270536,0.021873854,0.000012432076,0.00005646742,0.00010334268,0.00068311166,0.0000116087385,0.9653379,0.0001399267,0.00006799106,0.011060767],"study_design_scores_gemma":[0.002538696,0.00014330668,0.23543264,0.00014346786,0.000031748943,0.00008493121,0.0003177037,0.00020422268,0.75910926,0.0018620206,0.000059704675,0.000072280476],"about_ca_topic_score_codex":0.00016006404,"about_ca_topic_score_gemma":0.000022648659,"teacher_disagreement_score":0.21355878,"about_ca_system_score_codex":0.000069012,"about_ca_system_score_gemma":0.00016438935,"threshold_uncertainty_score":0.34984195},"labels":[],"label_agreement":null},{"id":"W4389027495","doi":"10.1096/fasebj.30.1_supplement.948.1","title":"A role for Sarcolemmal Membrane‐Associated Protein (SLMAP) in mediating autophagy in endothelial cells through an AMPK‐dependent mechanism","year":2016,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Endoplasmic reticulum; Cell biology; Autophagy; Umbilical vein; Chemistry; Human umbilical vein endothelial cell; Endothelial stem cell; Biology; Biochemistry; Apoptosis; In vitro","score_opus":0.017802262062588167,"score_gpt":0.271665417999443,"score_spread":0.2538631559368548,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389027495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961719,0.00017815577,0.0008043045,0.00095247035,0.00024382991,0.0012351245,0.00010375535,0.00004537227,0.00026509125],"genre_scores_gemma":[0.99742657,0.00010765454,0.0005492193,0.00053062016,0.00060879166,0.0001381852,0.000008585822,0.00005121843,0.0005791536],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997651,0.0003449092,0.000599088,0.00026905577,0.000507858,0.0006281018],"domain_scores_gemma":[0.99892783,0.00020929772,0.0003035726,0.00027768777,0.00008567514,0.000195947],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014662974,0.00023981709,0.00042449145,0.00014849874,0.00017509473,0.00004006857,0.0003102307,0.00015743147,0.00034414325],"category_scores_gemma":[0.00020572428,0.00013819923,0.00017339938,0.00016565903,0.000063502346,0.0003319684,0.000039909828,0.00044006482,0.000023767503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00093174895,0.00043492304,0.00023168312,0.000015953767,0.00008102758,0.00020679465,0.0020961808,0.000017310074,0.99164027,0.001331015,0.000008938069,0.0030041796],"study_design_scores_gemma":[0.011252873,0.00061884534,0.0011712265,0.00031138456,0.000055093053,0.00009590577,0.0006735675,0.000571735,0.96455103,0.02042649,0.000082903956,0.00018895823],"about_ca_topic_score_codex":0.000106536965,"about_ca_topic_score_gemma":0.00015072478,"teacher_disagreement_score":0.027089227,"about_ca_system_score_codex":0.00031415725,"about_ca_system_score_gemma":0.00034648075,"threshold_uncertainty_score":0.56356007},"labels":[],"label_agreement":null},{"id":"W4389028477","doi":"10.1096/fasebj.31.1_supplement.1043.4","title":"ER stress antagonizes metabolic stress‐induced loss of epithelial barrier function to commensal bacteria via xenophagy","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Alberta Health Services; Alberta Health; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Harvey L. Neiman Health Policy Institute; Canadian Institutes of Health Research; Alberta Innovates - Health Solutions","keywords":"Barrier function; Internalization; Unfolded protein response; Cell biology; Endoplasmic reticulum; Autophagy; Tunicamycin; Chemistry; Intracellular; Biology; Microbiology; Cell; Apoptosis; Biochemistry","score_opus":0.020862689295946972,"score_gpt":0.29185435108696367,"score_spread":0.2709916617910167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389028477","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99592865,0.00042338975,0.0004002831,0.0011127867,0.0013073815,0.00026746053,0.00019693233,0.000020865657,0.00034226573],"genre_scores_gemma":[0.9968499,0.0001552005,0.000089314715,0.00077219476,0.0017221076,0.0000076617125,0.000014922337,0.00003663753,0.00035206493],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984986,0.00014833557,0.00039997662,0.0001797929,0.0004228473,0.00035042243],"domain_scores_gemma":[0.99816525,0.00005283215,0.00041205029,0.00078526424,0.00020700214,0.00037757217],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00040233703,0.00022277338,0.0004487499,0.00010541321,0.0006703684,0.0001161909,0.00044874,0.00009496152,0.0014261735],"category_scores_gemma":[0.000085687454,0.00014010492,0.00021884534,0.00006285607,0.00015484449,0.00021833449,0.000092940194,0.00039985764,0.00006677663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027119047,0.0002572185,0.018233826,0.000025069032,0.00071293523,0.0001476039,0.0007020841,0.000009228131,0.962064,0.00014630465,0.00028662157,0.014703168],"study_design_scores_gemma":[0.0026716136,0.00045635138,0.2451519,0.000119560085,0.00042453522,0.00014720211,0.00020232445,0.000039334365,0.7494724,0.00035551417,0.0008165848,0.00014266041],"about_ca_topic_score_codex":0.00007953551,"about_ca_topic_score_gemma":0.000011692417,"teacher_disagreement_score":0.22691809,"about_ca_system_score_codex":0.000030991578,"about_ca_system_score_gemma":0.00014801894,"threshold_uncertainty_score":0.9994867},"labels":[],"label_agreement":null},{"id":"W4389034036","doi":"10.1096/fasebj.30.1_supplement.1010.7","title":"The Correlation Between Tfeb and PGC‐1α in Skeletal Muscle","year":2016,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"TFEB; Basic helix-loop-helix leucine zipper transcription factors; Autophagy; Biogenesis; NRF1; Cell biology; Transcription factor; Biology; Mitochondrial biogenesis; Mitophagy; Mitochondrion; Chemistry; Biochemistry; Gene; DNA-binding protein","score_opus":0.014356207988365927,"score_gpt":0.2665949078487648,"score_spread":0.2522386998603988,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389034036","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927891,0.001248306,0.00045989593,0.0046442477,0.00013050516,0.00010184378,0.0000031901225,0.00000959446,0.0006133195],"genre_scores_gemma":[0.9978428,0.0006607521,0.000013719677,0.00019893084,0.00046093046,0.0000021382068,9.323134e-7,0.000008616,0.0008112088],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9993607,0.00008578278,0.00016498691,0.00006458551,0.00016486766,0.00015911949],"domain_scores_gemma":[0.9994187,0.0002547735,0.000073882584,0.00013607326,0.000025917027,0.00009064824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004972449,0.000066302346,0.00009557206,0.000033147564,0.00022039689,0.000025334297,0.00006834796,0.00003588691,0.00010399818],"category_scores_gemma":[0.00006169343,0.000025477988,0.000049110367,0.000060225604,0.00011271713,0.000076938246,0.000017670234,0.00020069689,0.000036992056],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023332988,0.00008479401,0.17722957,0.00000857743,0.00020547996,0.00017766218,0.0011914381,0.0000047231338,0.056020647,0.001290955,0.0016841398,0.7618687],"study_design_scores_gemma":[0.0022762765,0.00015467864,0.98170245,0.000107688415,0.00006887284,0.0002053612,0.00019217507,0.00007537916,0.004268406,0.0055465987,0.005332335,0.000069770016],"about_ca_topic_score_codex":0.0000052625496,"about_ca_topic_score_gemma":0.0000037831044,"teacher_disagreement_score":0.8044729,"about_ca_system_score_codex":0.000034873814,"about_ca_system_score_gemma":0.000051063336,"threshold_uncertainty_score":0.1695137},"labels":[],"label_agreement":null},{"id":"W4389138908","doi":"10.1080/15548627.2023.2288528","title":"CARM1 drives mitophagy and autophagy flux during fasting-induced skeletal muscle atrophy","year":2023,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Queen's University; McMaster University","funders":"University of Texas MD Anderson Cancer Center; School of Medicine, Stanford University; Canadian Frailty Network; Ontario Ministry of Economic Development, Job Creation and Trade; Ministero dello Sviluppo Economico; Canada Research Chairs; Natural Sciences and Engineering Research Council of Canada; McMaster University","keywords":"Biology; Mitophagy; Autophagy; Skeletal muscle; Sequestosome 1; Cell biology; FOXO3; Mechanistic target of rapamycin; Muscle atrophy; PINK1; Mitochondrial biogenesis; ULK1; AMP-activated protein kinase; Mitochondrion; PI3K/AKT/mTOR pathway; AMPK; Endocrinology; Protein kinase A; Biochemistry; Protein kinase B; Kinase; Phosphorylation; Signal transduction","score_opus":0.014712134171409362,"score_gpt":0.2720647999009836,"score_spread":0.2573526657295742,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389138908","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921445,0.0016740015,0.000021694008,0.0004325336,0.0007564711,0.00058684807,0.000027236698,0.0012644685,0.003092222],"genre_scores_gemma":[0.9897006,0.00026215988,0.00027972955,0.0004884486,0.0008799864,0.00009119866,0.00009433167,0.00013690656,0.008066598],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9968683,0.00010112005,0.0005694862,0.000906422,0.00057172094,0.0009829244],"domain_scores_gemma":[0.9982369,0.00017673476,0.00016634454,0.0007481714,0.000108830296,0.0005630108],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00019317346,0.0005259598,0.00072280044,0.00045652274,0.00052382034,0.00008050899,0.0002456588,0.00028000193,0.000626492],"category_scores_gemma":[0.00016251745,0.00050252373,0.00033166443,0.0008433289,0.0002780905,0.0002599943,0.00023602007,0.00042946095,0.0008564901],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019181753,0.00035464708,0.002343319,0.0005986845,0.0005676685,0.005327685,0.0018351583,0.000035061006,0.9458633,0.0011922967,0.0015237946,0.040166583],"study_design_scores_gemma":[0.0046472587,0.0005698385,0.8010851,0.00016298785,0.00018182697,0.00026129838,0.000270722,0.0012044916,0.18720646,0.0008104193,0.0029940566,0.0006055445],"about_ca_topic_score_codex":0.00006924448,"about_ca_topic_score_gemma":0.0000065825825,"teacher_disagreement_score":0.79874176,"about_ca_system_score_codex":0.00012218552,"about_ca_system_score_gemma":0.00023775322,"threshold_uncertainty_score":0.99992144},"labels":[],"label_agreement":null},{"id":"W4389269480","doi":"10.1080/15548627.2023.2286414","title":"Basal activity of PINK1 and PRKN in cell models and rodent brain","year":2023,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Aging; National Institute of Neurological Disorders and Stroke; National Institute on Aging; Florida Department of Health; Congressionally Directed Medical Research Programs; Mayo Clinic; American Parkinson Disease Association; U.S. Department of Defense","keywords":"PINK1; Mitophagy; Biology; Autophagy; Ubiquitin ligase; Ubiquitin; Cell biology; Parkin; Mitochondrion; Basal (medicine); Parkinson's disease; Neuroscience; Disease; Internal medicine; Endocrinology; Apoptosis; Genetics; Medicine","score_opus":0.02310461190578223,"score_gpt":0.2926898597496608,"score_spread":0.26958524784387855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389269480","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99685705,0.0008921119,0.00007621787,0.0007461017,0.00004644561,0.0002244993,0.000009821944,0.00005348339,0.0010942573],"genre_scores_gemma":[0.9980332,0.00036611807,0.00006670581,0.00038796128,0.000032219745,0.000014559771,0.000006205439,0.0000160954,0.0010768984],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999279,0.00003957984,0.00014262034,0.00021362389,0.00014433172,0.0001808105],"domain_scores_gemma":[0.9995667,0.00009669218,0.000043815086,0.00017780806,0.000017039922,0.00009796373],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018154943,0.00010335096,0.00025556152,0.00013203561,0.000022847937,0.000006365009,0.00003890203,0.00007248151,0.000039234772],"category_scores_gemma":[0.000021315109,0.000093730894,0.000035135632,0.00019478182,0.00006771812,0.000095039424,0.000054143133,0.00010231109,0.000008504549],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023484905,0.0023691624,0.04812117,0.002325941,0.0003717567,0.0019027678,0.010917066,0.00080151623,0.78479105,0.0073649525,0.006913951,0.13177218],"study_design_scores_gemma":[0.004443968,0.00037559072,0.7640573,0.00010563563,0.000045941502,0.00001618295,0.00012103605,0.040960964,0.17959952,0.009754393,0.00032575586,0.00019374218],"about_ca_topic_score_codex":0.000108028005,"about_ca_topic_score_gemma":0.000010668295,"teacher_disagreement_score":0.7159361,"about_ca_system_score_codex":0.00001617622,"about_ca_system_score_gemma":0.000056804332,"threshold_uncertainty_score":0.3822235},"labels":[],"label_agreement":null},{"id":"W4389336467","doi":"10.1016/j.devcel.2023.11.006","title":"An Arabidopsis Rab18 GTPase promotes autophagy by tethering ATG18a to the ER in response to nutrient starvation","year":2023,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; State Key Laboratory of Mechanical Transmissions; Harbin Institute of Technology; Shandong University; National Natural Science Foundation of China; McGill University","keywords":"Autophagy; Endoplasmic reticulum; Biology; Cell biology; GTPase; Autophagosome; Unfolded protein response; Effector; Starvation response; Arabidopsis; Small GTPase; Mutant; Starvation; Signal transduction; Biochemistry; Gene; Apoptosis; Endocrinology","score_opus":0.0144262151622644,"score_gpt":0.27593029761367094,"score_spread":0.26150408245140655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389336467","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99604005,0.00006650432,0.0001089507,0.002204953,0.00011496184,0.0010043648,0.000025513255,0.00013686177,0.0002978551],"genre_scores_gemma":[0.99277043,0.000015243674,0.0011819941,0.0026719745,0.000044820215,0.00022495624,0.00010901107,0.000036899186,0.002944663],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986513,0.00010061371,0.0002665598,0.00033219854,0.0003125722,0.0003367313],"domain_scores_gemma":[0.9993739,0.00007238871,0.00003442315,0.00024537637,0.000034811852,0.00023907865],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00060017017,0.0001676574,0.00017110111,0.00021105612,0.00010823535,0.000030680098,0.00015801765,0.000056998746,0.00022151972],"category_scores_gemma":[0.000062952546,0.00013028314,0.00003741967,0.0007762558,0.000018954832,0.00008226583,0.00006442758,0.000115544164,0.00080796704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003421155,0.0006252205,0.0057014553,0.00005352441,0.000040821127,0.00024515574,0.017362121,0.00009057405,0.94487464,0.000022286667,0.015401613,0.012161402],"study_design_scores_gemma":[0.0017641321,0.00045766274,0.22233737,0.00009405531,0.000013071659,0.0000074837994,0.0015750853,0.00028917487,0.68898946,0.00009011767,0.08408924,0.00029312863],"about_ca_topic_score_codex":0.000046397192,"about_ca_topic_score_gemma":0.00001750784,"teacher_disagreement_score":0.25588518,"about_ca_system_score_codex":0.00025605515,"about_ca_system_score_gemma":0.00016377836,"threshold_uncertainty_score":0.99997},"labels":[],"label_agreement":null},{"id":"W4389343455","doi":"10.1016/j.clnesp.2023.09.818","title":"Efficacy of pancreatic enzyme replacement therapy for muscle mass maintenance is dose dependent in patients with advanced pancreatic cancer","year":2023,"lang":"en","type":"article","venue":"Clinical Nutrition ESPEN","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Pancreatic cancer; Pancreatic enzymes; Cancer; Maintenance therapy; Internal medicine; Oncology; Gastroenterology; Pancreas; Chemotherapy","score_opus":0.036417143744848585,"score_gpt":0.3676062441790778,"score_spread":0.3311891004342292,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389343455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947,0.0005715114,0.00011791796,0.0009572105,0.0001310523,0.0032836606,0.00011271383,0.00006385079,0.000062061896],"genre_scores_gemma":[0.9918202,0.004571875,0.00072765443,0.0012518865,0.00011662371,0.00090762996,0.00018909706,0.000040720213,0.00037432314],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9980274,0.00008831285,0.00077058247,0.0004530221,0.00033611525,0.0003245605],"domain_scores_gemma":[0.9983891,0.0005567104,0.00025325664,0.0004555282,0.00019081493,0.00015454694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038383645,0.0001860455,0.0006302124,0.000111638255,0.000041577263,0.000008668323,0.0001253258,0.00011198881,0.00027040066],"category_scores_gemma":[0.00018963468,0.00014177703,0.00019160876,0.00033962302,0.000100235164,0.000081275095,0.000019472734,0.00015076039,0.000023916147],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.17088954,0.018491453,0.66925216,0.0014545538,0.0013189489,0.000077965946,0.0007091113,0.00012029941,0.0046354914,0.00022809388,0.0100269625,0.12279542],"study_design_scores_gemma":[0.08257656,0.003812706,0.9035458,0.0013165132,0.00013958276,3.7382168e-7,0.00011185554,0.00028418537,0.004263242,0.0008220383,0.0029183917,0.0002087607],"about_ca_topic_score_codex":0.000017382026,"about_ca_topic_score_gemma":0.000005278794,"teacher_disagreement_score":0.23429362,"about_ca_system_score_codex":0.00009117461,"about_ca_system_score_gemma":0.00010096157,"threshold_uncertainty_score":0.57815},"labels":[],"label_agreement":null},{"id":"W4389739633","doi":"10.1152/japplphysiol.00484.2023","title":"The role of TFE3 in mediating skeletal muscle mitochondrial adaptations to exercise training","year":2023,"lang":"en","type":"article","venue":"Journal of Applied Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"CIHR Skin Research Training Centre; Canada Research Chairs; Government of Canada","keywords":"Mitophagy; Endurance training; Skeletal muscle; Stimulation; Biology; Mitochondrion; Endocrinology; Internal medicine; Autophagy; Cell biology; Medicine; Biochemistry; Apoptosis","score_opus":0.015432276274133596,"score_gpt":0.2793394072932157,"score_spread":0.26390713101908214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389739633","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985233,0.00021005217,0.000012643778,0.00025068657,0.00022324367,0.00017142278,0.0000030484211,0.000009210778,0.0005964241],"genre_scores_gemma":[0.9987751,0.00015215615,0.0004394319,0.000102084814,0.00047979972,0.000019486391,0.0000049629402,0.00001179718,0.000015145071],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991415,0.00002320242,0.00040188673,0.00008375646,0.00016369633,0.00018591949],"domain_scores_gemma":[0.99927485,0.0002483549,0.0002148952,0.00011403362,0.000060246577,0.00008764913],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018776367,0.000073602605,0.00030306,0.00014355258,0.00005495689,0.0000031680522,0.00011646086,0.00005243988,0.000024395309],"category_scores_gemma":[0.000067227156,0.00005046183,0.00010221751,0.00030795284,0.000052982963,0.000024386687,0.00002310824,0.00019098802,0.000015071296],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005470285,0.00006108003,0.000017216733,0.000007816882,0.00005104654,0.000009814455,0.004590741,0.00081704144,0.90040845,0.0010068661,0.00012215918,0.09236074],"study_design_scores_gemma":[0.010886508,0.0014743535,0.68770003,0.00038315103,0.00030894938,0.000030821226,0.049775578,0.0032376335,0.13542125,0.0917391,0.018624786,0.00041782868],"about_ca_topic_score_codex":0.0000035805751,"about_ca_topic_score_gemma":0.000002615541,"teacher_disagreement_score":0.76498723,"about_ca_system_score_codex":0.00001797021,"about_ca_system_score_gemma":0.0001376234,"threshold_uncertainty_score":0.20577738},"labels":[],"label_agreement":null},{"id":"W4390264444","doi":"10.1002/adbi.202300560","title":"Temperature‐Dependent Relationship of Autophagy and Apoptotic Signaling During Cold‐Water Immersion in Young and Older Males","year":2023,"lang":"en","type":"article","venue":"Advanced Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Apoptosis; Cold-shock domain; Peripheral blood mononuclear cell; Cell biology; In vivo; Inflammation; Heat shock protein; In vitro; Biology; Chemistry; Medicine; Immunology; Biochemistry","score_opus":0.010319112128062443,"score_gpt":0.2796774473326331,"score_spread":0.26935833520457064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390264444","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981745,0.001352348,0.000008020599,0.00011983456,0.000072824434,0.00020068833,0.000004713867,0.00003147787,0.00003563096],"genre_scores_gemma":[0.99911886,0.00038012353,0.0001219497,0.000048547266,0.000024771112,0.0000152408065,0.000037703547,0.000010636458,0.00024216162],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9993513,0.000041414245,0.00017921299,0.0002017832,0.00004630506,0.00017994511],"domain_scores_gemma":[0.9997362,0.00006570882,0.000034787987,0.00009609672,0.000020063591,0.000047150363],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010591195,0.00008961232,0.00019444784,0.00014614494,0.000050982075,0.0000030295278,0.000025236284,0.00010229476,0.000024665782],"category_scores_gemma":[0.000025730054,0.00006624426,0.000021548425,0.000108052336,0.00007541108,0.00005153061,0.00003510633,0.0001110456,0.0000060470265],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013046541,0.000019554069,0.16758256,0.00007494925,0.000014124675,0.000026342554,0.00026209038,0.00003762046,0.8313118,0.00028618635,7.269898e-7,0.00025353773],"study_design_scores_gemma":[0.0014930678,0.00008570637,0.558596,0.000077080695,0.00001528702,0.000021625414,0.00021256882,0.00003393015,0.4389397,0.00045723558,0.0000063031607,0.0000614798],"about_ca_topic_score_codex":0.00000923058,"about_ca_topic_score_gemma":0.0000042581382,"teacher_disagreement_score":0.39237213,"about_ca_system_score_codex":0.000016787497,"about_ca_system_score_gemma":0.000010856482,"threshold_uncertainty_score":0.27013627},"labels":[],"label_agreement":null},{"id":"W4390545287","doi":"10.1080/15548627.2023.2299516","title":"DIRAS3 induces autophagy and enhances sensitivity to anti-autophagic therapy in KRAS-driven pancreatic and ovarian carcinomas","year":2024,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Ovarian Cancer Research Alliance; Cancer Prevention and Research Institute of Texas; University of Texas MD Anderson Cancer Center; Ovarian Cancer Research Fund Alliance; National Cancer Institute; U.S. Department of Health and Human Services","keywords":"KRAS; Biology; Autophagy; Cancer research; Carcinogenesis; Oncogene; Pancreatic cancer; YAP1; Apoptosis; Cancer cell; Cell growth; Cell cycle; Cancer; Transcription factor; Colorectal cancer; Gene","score_opus":0.016957203379783466,"score_gpt":0.2865135172913191,"score_spread":0.2695563139115356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390545287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9756739,0.020726226,0.00007599662,0.0010458389,0.00037919506,0.000878916,0.000028484585,0.00033100048,0.00086041674],"genre_scores_gemma":[0.9944122,0.0025048368,0.00038308735,0.0015577484,0.00031139,0.0000876758,0.000022106831,0.00007605721,0.00064491894],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9974172,0.00020792123,0.00047394066,0.00094262755,0.00035534654,0.00060295133],"domain_scores_gemma":[0.99863005,0.00038668443,0.00006457516,0.00045120114,0.000050831124,0.00041664008],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043513635,0.00046930937,0.0008482434,0.0004880725,0.00013264417,0.00016644168,0.000105121275,0.00022953964,0.00019140235],"category_scores_gemma":[0.00007366025,0.0003971163,0.000117099305,0.0006502557,0.00020470643,0.00031230526,0.000105771556,0.00039384447,0.00007229],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049947354,0.00064059044,0.03430956,0.0007289783,0.0007914922,0.009607275,0.008526018,0.000029725214,0.74319136,0.006706992,0.00031945622,0.19464909],"study_design_scores_gemma":[0.0018807638,0.0006519312,0.84899676,0.0004518184,0.00012582376,0.00044755897,0.00016797369,0.0027299954,0.14076932,0.0012078715,0.0020918217,0.0004783811],"about_ca_topic_score_codex":0.00049405434,"about_ca_topic_score_gemma":0.000053576798,"teacher_disagreement_score":0.8146872,"about_ca_system_score_codex":0.00009090229,"about_ca_system_score_gemma":0.00022534159,"threshold_uncertainty_score":0.99984807},"labels":[],"label_agreement":null},{"id":"W4390562608","doi":"10.1016/j.molp.2024.01.002","title":"Eat at the right time: Regulation of ER-phagy receptors in plant response to environmental stresses","year":2024,"lang":"en","type":"article","venue":"Molecular Plant","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China; Shandong University","keywords":"Receptor; Endoplasmic reticulum; Autophagy; Cell biology; Biology; Phosphorylation; Biochemistry; Apoptosis","score_opus":0.004007215753397105,"score_gpt":0.22418657275368872,"score_spread":0.22017935700029162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390562608","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99553907,0.0025035548,0.00003857189,0.0008836624,0.00010386451,0.00033707358,0.0002910993,0.000027517897,0.0002756101],"genre_scores_gemma":[0.9967317,0.00007239628,0.000040339924,0.00029999638,0.000030008516,0.000020517273,0.00038259864,0.000020013322,0.0024024553],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990747,0.00011980889,0.0001896538,0.00020779857,0.00026065658,0.00014740792],"domain_scores_gemma":[0.99952966,0.00010978817,0.000026591106,0.00025673964,0.0000036451777,0.000073567375],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001914412,0.00011550679,0.00015701566,0.00011548148,0.000030624025,0.000009331974,0.000071448216,0.000058028865,0.0013783458],"category_scores_gemma":[0.00002064352,0.00007659737,0.00006902173,0.00012083357,0.00004731189,0.000024071596,0.000040943778,0.00008379123,0.00022915266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029756567,0.00010924753,0.00038494694,0.000037549813,0.00010038027,0.0011481821,0.0005895113,0.00015911038,0.9863668,0.00010636985,0.0067773387,0.0012449117],"study_design_scores_gemma":[0.00054830767,0.0002414121,0.022059482,0.00026826217,0.00006207057,0.00010726334,0.00004179063,0.00068258215,0.93166816,0.000084742824,0.04412419,0.00011171928],"about_ca_topic_score_codex":0.000014014527,"about_ca_topic_score_gemma":0.0000060211505,"teacher_disagreement_score":0.054698616,"about_ca_system_score_codex":0.00011020854,"about_ca_system_score_gemma":0.000040667554,"threshold_uncertainty_score":0.99953455},"labels":[],"label_agreement":null},{"id":"W4390774666","doi":"10.1038/s41467-023-44005-4","title":"Upregulated pexophagy limits the capacity of selective autophagy","year":2024,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Occupational Cancer Research Centre; Hospital for Sick Children; University of Toronto","funders":"CIHR Skin Research Training Centre; Government of Canada","keywords":"Autophagy; Cell biology; ULK1; Downregulation and upregulation; Peroxisome; ATG16L1; Mitophagy; Protein degradation; Mitochondrion; Biology; Chemistry; Biochemistry; Apoptosis; Protein kinase A; Phosphorylation; Gene","score_opus":0.028274988345061654,"score_gpt":0.3335276777641619,"score_spread":0.3052526894191003,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390774666","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.77783537,0.16853654,0.00013447947,0.016881872,0.00052793615,0.0010366336,0.00010909257,0.0005401661,0.03439793],"genre_scores_gemma":[0.9965737,0.0011763759,0.0007181355,0.00068934093,0.00007242945,0.000043544096,0.000058883616,0.000021511907,0.00064609485],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919736,0.00012691822,0.00020368052,0.00015102884,0.00018761051,0.00013337645],"domain_scores_gemma":[0.9977253,0.00040761428,0.000051372943,0.0015350296,0.0002195356,0.000061144805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017981771,0.00011407004,0.00017915496,0.000089498935,0.00017154045,0.000018932002,0.0005251015,0.00022726308,0.000077657794],"category_scores_gemma":[0.00012589601,0.00007534061,0.00015327187,0.00066737155,0.00027521065,0.00006757872,0.00008023017,0.0010709866,0.0000332712],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036452155,0.002052946,0.0021189335,0.00042906313,0.0039602485,0.000047931542,0.010635916,0.00003847262,0.23453252,0.6371588,0.07531467,0.03334598],"study_design_scores_gemma":[0.0015003287,0.00038803197,0.30239525,0.0006483628,0.0012041476,0.0002460988,0.00031462472,0.012782574,0.4643515,0.01493139,0.2007998,0.00043787961],"about_ca_topic_score_codex":0.000021144919,"about_ca_topic_score_gemma":0.000025083273,"teacher_disagreement_score":0.62222743,"about_ca_system_score_codex":0.00005806175,"about_ca_system_score_gemma":0.00019503184,"threshold_uncertainty_score":0.46529633},"labels":[],"label_agreement":null},{"id":"W4391033120","doi":"10.1007/s00280-023-04636-2","title":"Correction to: Up-regulation of autophagy is a mechanism of resistance to chemotherapy and can be inhibited by pantoprazole to increase drug sensitivity","year":2024,"lang":"en","type":"erratum","venue":"Cancer Chemotherapy and Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Pantoprazole; Mechanism (biology); Pharmacology; Autophagy; Drug; Drug resistance; Chemotherapy; Sensitivity (control systems); Medicine; Chemistry; Biology; Internal medicine; Biochemistry; Genetics","score_opus":0.00926900909796378,"score_gpt":0.30537013380570016,"score_spread":0.29610112470773636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391033120","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94060713,0.012418826,0.00038015994,0.025514413,0.015143496,0.0028423788,0.0020014204,0.00014192975,0.00095024146],"genre_scores_gemma":[0.72043407,0.013037989,0.00018895205,0.07246628,0.0017450722,0.0003811128,0.00034749,0.00022043615,0.19117858],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978154,0.0001359335,0.00052899675,0.00081028783,0.0003263164,0.00038307314],"domain_scores_gemma":[0.99852365,0.00012015395,0.00026718617,0.0002968462,0.00030433323,0.00048784915],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031620704,0.00049953425,0.0010781225,0.00037707848,0.00008235969,0.000017163686,0.000098168755,0.00036871654,0.00087397447],"category_scores_gemma":[0.000022432621,0.0004965589,0.00012858519,0.0006722847,0.00013015946,0.000050346447,0.00005683095,0.00050342066,0.0000027532385],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027539167,0.00010287185,0.000019250629,0.00054215686,0.00042099858,0.000010088698,0.003687658,0.0000021024218,0.407484,0.000019340376,0.57788736,0.0070702913],"study_design_scores_gemma":[0.0024587822,0.00035194578,0.000559545,0.0006529364,0.00032988712,0.000013852597,0.000090314694,0.0003487235,0.7124607,0.0001513024,0.28224066,0.00034133205],"about_ca_topic_score_codex":0.0011496329,"about_ca_topic_score_gemma":0.0003814124,"teacher_disagreement_score":0.3049767,"about_ca_system_score_codex":0.00023185485,"about_ca_system_score_gemma":0.00052992936,"threshold_uncertainty_score":0.9997486},"labels":[],"label_agreement":null},{"id":"W4391057846","doi":"10.1101/2024.01.20.576435","title":"Axonal distribution of mitochondria maintains neuronal autophagy during aging via eIF2β","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Institute of General Medical Sciences; Directorate for Biological Sciences; National Institutes of Health; NOVARTIS Foundation (Japan) for the Promotion of Science; Novartis Foundation; Tokyo Metropolitan University; National Center for Geriatrics and Gerontology; Japan Foundation for Aging and Health; Hoansha Foundation","keywords":"Proteostasis; Autophagy; Cell biology; Axon; Mitochondrion; Biology; Axoplasmic transport; Neurodegeneration; Neuroscience; Biochemistry; Apoptosis; Pathology; Medicine","score_opus":0.00850942816506338,"score_gpt":0.23313745954636075,"score_spread":0.22462803138129736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391057846","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908582,0.0030585208,0.001381611,0.00039107696,0.0020078209,0.0008685602,0.00082941307,0.0005901122,0.000014682404],"genre_scores_gemma":[0.9971596,0.00019943962,0.0007459351,0.00017104148,0.0013360626,0.00015980145,0.00000784798,0.00018995118,0.00003033083],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964575,0.00011384643,0.0008504622,0.0011524941,0.000732781,0.00069287076],"domain_scores_gemma":[0.99740565,0.000055649383,0.0004090518,0.001258052,0.0004113095,0.0004602959],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030253228,0.000700439,0.0009075555,0.00033651444,0.00014172925,0.00009797473,0.00038630416,0.00055084366,0.00019902117],"category_scores_gemma":[0.00011171267,0.00072977814,0.0005250338,0.00054023665,0.00021406217,0.0000907962,0.00066370796,0.0014062313,0.000117465825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025941856,0.00040203935,0.0032562367,0.003142243,0.00082404225,0.00083467783,0.000015049018,0.00006139981,0.98901993,0.0018747261,0.00030471888,0.0000055415226],"study_design_scores_gemma":[0.0012160786,0.0001013632,0.38505808,0.0013699628,0.00067308993,3.877382e-7,0.0000023469986,0.0009795973,0.60911465,0.000045014232,0.0008231489,0.00061628036],"about_ca_topic_score_codex":0.00003512031,"about_ca_topic_score_gemma":6.1684773e-7,"teacher_disagreement_score":0.3818018,"about_ca_system_score_codex":0.0005261387,"about_ca_system_score_gemma":0.0010471416,"threshold_uncertainty_score":0.99951535},"labels":[],"label_agreement":null},{"id":"W4391324083","doi":"10.3390/antiox13020171","title":"Antioxidative Sirt1 and the Keap1-Nrf2 Signaling Pathway Impair Inflammation and Positively Regulate Autophagy in Murine Mammary Epithelial Cells or Mammary Glands Infected with Streptococcus uberis","year":2024,"lang":"en","type":"article","venue":"Antioxidants","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Natural Science Foundation of China","keywords":"Streptococcus uberis; Oxidative stress; Autophagy; Biology; Inflammation; Reactive oxygen species; Superoxide dismutase; Immunology; Endocrinology; Cell biology; Biochemistry; Streptococcus; Apoptosis","score_opus":0.006921156681341576,"score_gpt":0.24113517129184944,"score_spread":0.23421401461050786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391324083","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951972,0.0015224282,0.0008605269,0.0006514349,0.00009918492,0.0011416533,0.00006191192,0.00020607871,0.00025961528],"genre_scores_gemma":[0.9973516,0.0011344904,0.00035543452,0.00018760667,0.00016898886,0.00007112247,0.000053442414,0.00004559644,0.0006317527],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981471,0.00021893719,0.0004474378,0.000526392,0.0002980396,0.00036211798],"domain_scores_gemma":[0.99899983,0.0002989331,0.00013270944,0.00031714948,0.00009920488,0.00015219158],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045107902,0.00035135783,0.000506754,0.00028141102,0.00013445487,0.00016444347,0.000111325055,0.0001474404,0.000051852145],"category_scores_gemma":[0.00004379571,0.00020742863,0.00008126982,0.00054555025,0.00026100056,0.00056155195,0.00010370313,0.00031692017,0.000009220131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007682502,0.00032045768,0.015121138,0.0010409952,0.0012668755,0.006442549,0.0057676397,0.000032983713,0.8857874,0.00448452,0.000093445866,0.07195944],"study_design_scores_gemma":[0.010761379,0.000790351,0.44504356,0.001359301,0.00020271896,0.00037786248,0.0002001479,0.0047862087,0.5344296,0.0013043501,0.0003069084,0.00043760266],"about_ca_topic_score_codex":0.00007740423,"about_ca_topic_score_gemma":0.000034449407,"teacher_disagreement_score":0.42992243,"about_ca_system_score_codex":0.00004504524,"about_ca_system_score_gemma":0.0002629292,"threshold_uncertainty_score":0.8458694},"labels":[],"label_agreement":null},{"id":"W4391483026","doi":"10.1016/j.canlet.2024.216661","title":"Immune checkpoints between epithelial-mesenchymal transition and autophagy: A conflicting triangle","year":2024,"lang":"en","type":"review","venue":"Cancer Letters","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"CancerCare Manitoba Foundation","keywords":"Autophagy; Immune system; Biology; Epithelial–mesenchymal transition; Downregulation and upregulation; Cell biology; Cancer cell; Cancer research; Innate immune system; Immune checkpoint; Metastasis; Immunotherapy; Apoptosis; Cancer; Immunology; Gene","score_opus":0.05084514827719955,"score_gpt":0.38733396712833057,"score_spread":0.336488818851131,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391483026","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002485216,0.99308634,0.00005063561,0.0018789404,0.0006242884,0.0010645025,0.0004840696,0.00017016786,0.00015586361],"genre_scores_gemma":[0.00039645433,0.99443233,0.00003994717,0.0016302556,0.0022338096,0.0002932791,0.00031852475,0.00012661483,0.00052879314],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998057,0.00009937218,0.0006547016,0.0005747861,0.0002445457,0.00036956475],"domain_scores_gemma":[0.9991319,0.000087798595,0.00021104749,0.0003393399,0.000025047437,0.00020482813],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024243025,0.00049995974,0.0019977824,0.00024740875,0.00008387109,0.000057280984,0.00011783927,0.00028768007,0.00023779957],"category_scores_gemma":[0.000017947834,0.00038837708,0.0007359611,0.00029215225,0.00013337262,0.00007597413,0.000033014243,0.0006559848,0.00013677226],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003742758,0.000022383989,0.000003385786,0.022836441,0.0017084522,0.0004097436,0.00062905345,1.9211654e-7,0.00035115736,0.000015565754,0.0014043052,0.97258186],"study_design_scores_gemma":[0.0012523275,0.00006766867,0.00008031636,0.025843957,0.008317267,0.0000934541,0.000017109993,0.0000079267,0.00024634518,0.000016048381,0.9636376,0.0004199709],"about_ca_topic_score_codex":0.000053277792,"about_ca_topic_score_gemma":6.306678e-7,"teacher_disagreement_score":0.97216195,"about_ca_system_score_codex":0.00024564014,"about_ca_system_score_gemma":0.00033315097,"threshold_uncertainty_score":0.9998568},"labels":[],"label_agreement":null},{"id":"W4391536690","doi":"10.1080/27694127.2024.2305594","title":"Molecular structures and function of the autophagosome-lysosome fusion machinery","year":2024,"lang":"en","type":"article","venue":"Autophagy Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute of General Medical Sciences; National Natural Science Foundation of China","keywords":"Autophagy; Autophagosome; Cell biology; Lysosome; Guanine nucleotide exchange factor; Rab; Biology; Vacuole; Function (biology); Organelle; GTPase; Computational biology; Chemistry; Cytoplasm; Biochemistry","score_opus":0.006271571042707688,"score_gpt":0.25183428588255813,"score_spread":0.24556271483985043,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391536690","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97743124,0.018575637,0.00014150424,0.00037691553,0.0012028252,0.00034955205,0.0000050665135,0.00017485296,0.0017424041],"genre_scores_gemma":[0.9978872,0.00011589637,0.000067573514,0.00056240225,0.00014846266,0.000016013637,0.000015704825,0.000036692378,0.0011500437],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985856,0.00004448603,0.00041158064,0.00038573117,0.0003856568,0.0001869798],"domain_scores_gemma":[0.9991097,0.000034654106,0.00012901166,0.0005666396,0.000052714153,0.0001073095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017083934,0.00019310291,0.00028322375,0.00011973716,0.000080108555,0.000030788717,0.000057473175,0.00012729826,0.0002757058],"category_scores_gemma":[0.000049313065,0.00012107099,0.0002100002,0.0002952787,0.00013252579,0.00009707248,0.00008081428,0.00022211879,0.0000045522797],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023747196,0.0002141779,0.016143579,0.0010500478,0.00089900976,0.0080604665,0.0005352504,0.0000967383,0.8716235,0.020874782,0.0016211475,0.07864382],"study_design_scores_gemma":[0.0005840205,0.00026576006,0.55244374,0.00033925963,0.0006344155,0.0034299456,0.000030318952,0.0013307905,0.39231116,0.037967626,0.010407912,0.0002550689],"about_ca_topic_score_codex":0.000027160333,"about_ca_topic_score_gemma":6.947318e-7,"teacher_disagreement_score":0.5363001,"about_ca_system_score_codex":0.000030066572,"about_ca_system_score_gemma":0.00017044434,"threshold_uncertainty_score":0.49371317},"labels":[],"label_agreement":null},{"id":"W4391618535","doi":"10.1080/15548627.2024.2314415","title":"RABC1, an Arabidopsis RAB18 regulates binding and subsequent detachment of autophagosomes from the ER in autophagy","year":2024,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Autophagy; Rab; Endoplasmic reticulum; Biology; Cell biology; GTPase; Arabidopsis; Unfolded protein response; Phagosome; Small GTPase; Vacuole; Biochemistry; Mutant; Cytoplasm; Signal transduction; Gene; Apoptosis; Intracellular","score_opus":0.018206113951600766,"score_gpt":0.2954801178274099,"score_spread":0.27727400387580914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391618535","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96741855,0.029635353,0.00003528189,0.0010384837,0.00049982575,0.00058847497,0.00008060381,0.00022572758,0.0004776803],"genre_scores_gemma":[0.9966296,0.0010060237,0.0003719378,0.0006028616,0.00027728704,0.00007385631,0.00010427696,0.00006664116,0.00086754415],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99754447,0.00017448442,0.0006644662,0.0006849324,0.00045925405,0.00047242164],"domain_scores_gemma":[0.9984854,0.00039670523,0.00011441018,0.0007248892,0.000052708965,0.0002259101],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004984655,0.00037055684,0.00062840834,0.0002710758,0.000103870116,0.00009486426,0.00025798246,0.000198789,0.0006980686],"category_scores_gemma":[0.000058948553,0.00025772565,0.00020585065,0.0005275208,0.00027558825,0.00030563216,0.00009860489,0.00035339085,0.00005574069],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001599072,0.0024414493,0.069900624,0.0012295379,0.0033080264,0.004983017,0.01984732,0.000192883,0.6030847,0.049196675,0.0027332907,0.24148342],"study_design_scores_gemma":[0.0029662324,0.0005170143,0.617459,0.000846443,0.00045536697,0.00012012792,0.00053487776,0.007945666,0.3559671,0.007225423,0.005475018,0.00048776652],"about_ca_topic_score_codex":0.0004459349,"about_ca_topic_score_gemma":0.000041765405,"teacher_disagreement_score":0.54755837,"about_ca_system_score_codex":0.00014354242,"about_ca_system_score_gemma":0.00024005577,"threshold_uncertainty_score":0.9999875},"labels":[],"label_agreement":null},{"id":"W4391795595","doi":"10.1016/j.bbrep.2024.101654","title":"Identification of mitophagy-related hub genes during the progression of spinal cord injury by integrated multinomial bioinformatics analysis","year":2024,"lang":"en","type":"article","venue":"Biochemistry and Biophysics Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"International Collaboration On Repair Discoveries","funders":"Xinxiang Medical University","keywords":"Mitophagy; Biology; Gene; Cell biology; Genetics; Computational biology; Autophagy; Apoptosis","score_opus":0.005683324386092541,"score_gpt":0.2927976856865481,"score_spread":0.2871143613004556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391795595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963436,0.0031830035,0.00005851736,0.000033706474,0.000095419615,0.00016064847,0.000057720485,0.000033717606,0.000033652646],"genre_scores_gemma":[0.9991385,0.00024924264,0.00007556441,0.0000045779298,0.000050197355,0.0000094343195,0.00019696659,0.000008001829,0.00026755975],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988994,0.000009970173,0.0006088697,0.00018926249,0.0002007179,0.00009179658],"domain_scores_gemma":[0.99914944,0.000010914155,0.00037360564,0.00029423257,0.000119890465,0.000051942472],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012290533,0.00012468663,0.00023388841,0.000058911177,0.0000519258,0.000021409309,0.000048231203,0.00010225463,0.000012948232],"category_scores_gemma":[0.00001996425,0.00008036315,0.00016500358,0.0005644131,0.0001771022,0.000057177367,0.000028798451,0.000099728204,5.6321034e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030816448,0.00011611402,0.002074169,0.00067916495,0.0006158932,0.000036031797,0.000058328198,9.778926e-7,0.971617,0.0000038476296,0.000050302042,0.024440033],"study_design_scores_gemma":[0.00012969266,0.00011303032,0.004207667,0.00020124656,0.0005532927,0.000047005116,0.00009471984,0.0013033068,0.9931732,0.000026430112,0.00007171474,0.00007872752],"about_ca_topic_score_codex":0.000009369117,"about_ca_topic_score_gemma":4.780695e-8,"teacher_disagreement_score":0.024361307,"about_ca_system_score_codex":0.000015143654,"about_ca_system_score_gemma":0.00007806847,"threshold_uncertainty_score":0.32771143},"labels":[],"label_agreement":null},{"id":"W4391850691","doi":"10.1016/j.canlet.2024.216659","title":"Autophagy-driven regulation of cisplatin response in human cancers: Exploring molecular and cell death dynamics","year":2024,"lang":"en","type":"article","venue":"Cancer Letters","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":110,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Canadian Cardiovascular Society; Terry Fox Research Institute; Canadian Cancer Society; Lotte and John Hecht Memorial Foundation","keywords":"Autophagy; Cisplatin; Programmed cell death; Cancer research; Biology; Apoptosis; Context (archaeology); Cancer cell; DNA damage; Cell biology; Cancer; Chemotherapy; Genetics","score_opus":0.02437099337817018,"score_gpt":0.2975845505229649,"score_spread":0.2732135571447947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391850691","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99537766,0.0025533203,0.000644363,0.00092108594,0.00014250689,0.00019337205,0.000015506525,0.000042788495,0.000109373505],"genre_scores_gemma":[0.99871486,0.00014333412,0.0002081615,0.0006601566,0.00006238051,0.00006915343,0.000014598172,0.000027032725,0.00010032852],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992714,0.000040723335,0.00018528788,0.0002181925,0.00013889307,0.00014550345],"domain_scores_gemma":[0.9996858,0.000037963513,0.000038456248,0.00016267782,0.00001593321,0.000059149457],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010460927,0.00010766549,0.00017330227,0.00017395554,0.000022424021,0.0000131678735,0.000042852953,0.000042342068,0.000052084783],"category_scores_gemma":[0.0000061537453,0.000107966735,0.000048680544,0.00017214338,0.000051341955,0.00009884661,0.000015935237,0.00012449517,0.0000013960224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052875886,0.00001841302,0.005526741,0.000347749,0.000060715258,0.00028505802,0.0014293352,0.002821313,0.98589474,0.00063094334,0.00012716331,0.002329076],"study_design_scores_gemma":[0.0031614245,0.00033587893,0.32712156,0.0022430988,0.00024197249,0.000015026704,0.00021816742,0.06567677,0.59938663,0.00054703414,0.00063602487,0.00041639223],"about_ca_topic_score_codex":0.00018875829,"about_ca_topic_score_gemma":0.000016137757,"teacher_disagreement_score":0.38650808,"about_ca_system_score_codex":0.00044070705,"about_ca_system_score_gemma":0.000113406015,"threshold_uncertainty_score":0.44027555},"labels":[],"label_agreement":null},{"id":"W4391884764","doi":"10.3389/fcvm.2024.1298014","title":"Trehalose promotes atherosclerosis regression in female mice","year":2024,"lang":"en","type":"article","venue":"Frontiers in Cardiovascular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Trehalose; Autophagy; Inflammation; Internal medicine; Endocrinology; TFEB; Cholesterol; Lipid metabolism; Foam cell; Medicine; Biology; Chemistry; Immunology; Lipoprotein; Biochemistry; Apoptosis","score_opus":0.01671801666253602,"score_gpt":0.2714234135178613,"score_spread":0.2547053968553253,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391884764","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5429724,0.44765475,0.0024659915,0.0013501273,0.0020786189,0.000863869,0.0000062535787,0.00018145991,0.0024265647],"genre_scores_gemma":[0.99202263,0.0044544423,0.0015442752,0.00033568934,0.000692281,0.000108052816,0.000045505934,0.00007365319,0.0007234426],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99772656,0.00016358682,0.00043380843,0.0006149504,0.00066207,0.0003990402],"domain_scores_gemma":[0.9990286,0.000049169987,0.000030607625,0.0006740099,0.000037792714,0.00017978944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010394136,0.00028874312,0.0010196189,0.000619309,0.00003495571,0.000014077659,0.00014597733,0.00019712142,0.000115443545],"category_scores_gemma":[0.00013578706,0.00020662883,0.00053146965,0.0009554642,0.00019227841,0.00011955698,0.00003458596,0.00044585773,0.000025054736],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009801851,0.00086456805,0.3661305,0.0031386637,0.0057162736,0.008996408,0.012165516,0.0001374532,0.010320678,0.00021052721,0.042196788,0.5491424],"study_design_scores_gemma":[0.023614602,0.0014100625,0.7372928,0.02856666,0.0029342708,0.00045276745,0.0054304944,0.007220249,0.012642336,0.0026142346,0.17650059,0.0013209292],"about_ca_topic_score_codex":0.00013372778,"about_ca_topic_score_gemma":0.000005040489,"teacher_disagreement_score":0.5478215,"about_ca_system_score_codex":0.00025522267,"about_ca_system_score_gemma":0.00011513896,"threshold_uncertainty_score":0.8426079},"labels":[],"label_agreement":null},{"id":"W4392206999","doi":"10.1007/978-1-0716-3710-4_23","title":"In Vivo Analysis of ER-Associated Protein Degradation and Ubiquitination in Arabidopsis thaliana","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Endoplasmic-reticulum-associated protein degradation; Endoplasmic reticulum; Ubiquitin; Unfolded protein response; Arabidopsis thaliana; Proteasome; Cell biology; Protein degradation; Arabidopsis; Vacuole; Autophagy; F-box protein; Biology; Ubiquitin ligase; Chemistry; Biochemistry; Mutant; Gene; Cytoplasm","score_opus":0.020123189069543083,"score_gpt":0.4037992787644024,"score_spread":0.38367608969485933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392206999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93269145,0.0018293675,0.06459825,0.00034370847,0.00003232148,0.00027159465,0.000009388419,0.000012116234,0.00021180458],"genre_scores_gemma":[0.94645566,0.00010660983,0.05303006,0.0001812885,0.0000065473205,0.00006561316,0.000047686393,0.000010403734,0.00009611489],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998474,0.00078949035,0.0003055846,0.00023982326,0.000059119808,0.00013196455],"domain_scores_gemma":[0.99964786,0.00012681712,0.00005399497,0.0001220671,0.000025350098,0.000023908644],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011811719,0.00008686565,0.00035792103,0.00100529,0.0000055975065,0.00000425076,0.000040657436,0.00015646545,0.00007480014],"category_scores_gemma":[0.00038184936,0.00007916379,0.00007051475,0.0015504404,0.00005202424,0.000027575303,0.000017387745,0.00013089036,3.71654e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059812242,0.00013803905,0.029912047,0.000060359886,0.0003323143,0.00012172688,0.00032779228,0.000029947938,0.94829154,0.0051205894,0.0000025841912,0.015603274],"study_design_scores_gemma":[0.0011723726,0.00021966515,0.122074924,0.00021165032,0.00039764078,0.0000033067313,0.00011253857,0.01894567,0.83756703,0.01898761,0.00014826735,0.00015935046],"about_ca_topic_score_codex":0.00038226796,"about_ca_topic_score_gemma":0.00017606733,"teacher_disagreement_score":0.11072451,"about_ca_system_score_codex":0.000078134675,"about_ca_system_score_gemma":0.000042420066,"threshold_uncertainty_score":0.32282057},"labels":[],"label_agreement":null},{"id":"W4392237334","doi":"10.1080/27694127.2024.2320605","title":"Crosstalk between myocardial autophagy and sterile inflammation in the development of heart failure","year":2024,"lang":"en","type":"review","venue":"Autophagy Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Crosstalk; Heart failure; Inflammation; Context (archaeology); Medicine; Bioinformatics; Biology; Immunology; Cell biology; Cardiology; Apoptosis; Genetics","score_opus":0.03781615511613359,"score_gpt":0.35985139096018803,"score_spread":0.32203523584405447,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392237334","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.053374555,0.94402105,0.0000075792673,0.000087749155,0.0003535552,0.0016802731,0.000023339058,0.00008948721,0.000362395],"genre_scores_gemma":[0.06863666,0.9258845,0.0012669447,0.00010920049,0.0013733448,0.0007358873,0.00095050863,0.00020201685,0.0008409588],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963635,0.00017231332,0.0018833473,0.00063843944,0.0005910218,0.00035134572],"domain_scores_gemma":[0.9983137,0.00014400667,0.0005947463,0.0007549736,0.00006373098,0.00012880421],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010460316,0.0005279721,0.0020820096,0.00035267608,0.00008908569,0.000078473226,0.0001381926,0.00045404283,0.000065782966],"category_scores_gemma":[0.00006951066,0.0003390828,0.00048653415,0.00049222074,0.00013781026,0.00010877254,0.00013042687,0.00055795995,0.000034488407],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002536718,0.0001369734,0.000689676,0.032985244,0.0015160263,0.0034536899,0.0032104307,5.470886e-7,0.000058113314,0.0001021404,0.0019646368,0.95585716],"study_design_scores_gemma":[0.0002716514,0.000082645645,0.0057354528,0.00730635,0.0015694827,0.0013394796,0.0000533769,0.0000017037669,0.00039015472,0.00021422704,0.9827292,0.00030626944],"about_ca_topic_score_codex":0.00001144086,"about_ca_topic_score_gemma":0.0000059658605,"teacher_disagreement_score":0.98076457,"about_ca_system_score_codex":0.000126562,"about_ca_system_score_gemma":0.001351374,"threshold_uncertainty_score":0.9999061},"labels":[],"label_agreement":null},{"id":"W4392242690","doi":"10.1073/pnas.2313540121","title":"Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress","year":2024,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Structural Genomics Consortium; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Parkinson Canada; Michael J. Fox Foundation for Parkinson's Research","keywords":"PINK1; Parkin; Mitophagy; Cell biology; Mitochondrion; Biology; Ubiquitin ligase; Inner mitochondrial membrane; Translocase; Autophagy; Ubiquitin; Biochemistry; Chromosomal translocation; Medicine; Parkinson's disease","score_opus":0.03247986743217131,"score_gpt":0.31918165788155295,"score_spread":0.28670179044938165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392242690","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9920439,0.0030606128,3.6504778e-7,0.0042134766,0.00003970922,0.00019555795,0.000032545227,0.00001089257,0.0004029448],"genre_scores_gemma":[0.9993159,0.00032116295,0.000109149754,0.000070855865,0.000111694244,0.000006086796,6.968962e-8,0.000003927822,0.000061109],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989672,0.0000059190957,0.00015880188,0.00016990633,0.0006092771,0.00008890175],"domain_scores_gemma":[0.999568,0.00019244678,0.000111221074,0.000007630438,0.00008667953,0.00003401783],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030533527,0.00007807952,0.0001445171,0.000075672375,0.000096281314,0.000017514509,0.00018497604,0.000058001464,0.00001311089],"category_scores_gemma":[0.00021084244,0.00004074213,0.000056808753,0.00032867104,0.00058302394,0.00025347943,0.000055997156,0.00012375742,1.4893033e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007801929,0.000047405687,0.004216918,0.00050553575,0.000054566633,3.559884e-8,0.0007453226,0.000009286826,0.98531437,0.0063466835,0.000062429026,0.0026194353],"study_design_scores_gemma":[0.0002246348,0.000063130916,0.090112194,0.0005193792,0.000048709444,0.0000099482595,0.00015936223,0.0016758635,0.90084726,0.0062284963,0.00006635593,0.000044667067],"about_ca_topic_score_codex":0.0000069147313,"about_ca_topic_score_gemma":1.7834874e-7,"teacher_disagreement_score":0.08589528,"about_ca_system_score_codex":0.0000093367835,"about_ca_system_score_gemma":0.000042954867,"threshold_uncertainty_score":0.2148176},"labels":[],"label_agreement":null},{"id":"W4392356786","doi":"10.1016/j.canlet.2024.216744","title":"Investigating autophagy and intricate cellular mechanisms in hepatocellular carcinoma: Emphasis on cell death mechanism crosstalk","year":2024,"lang":"en","type":"review","venue":"Cancer Letters","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Natural Science Foundation of China","keywords":"Autophagy; Cancer research; Carcinogenesis; Biology; Crosstalk; Context (archaeology); Epigenetics; Programmed cell death; Pyroptosis; Hepatocellular carcinoma; Mechanism (biology); Cancer; Bioinformatics; Medicine; Apoptosis; Genetics; Gene","score_opus":0.0463295531086455,"score_gpt":0.3196727546213555,"score_spread":0.27334320151271,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392356786","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.040680848,0.95611715,0.00023525622,0.00036314258,0.0006569119,0.0015605891,0.00011102004,0.00015462632,0.000120439945],"genre_scores_gemma":[0.02060949,0.9729517,0.00039221975,0.0039947107,0.0004475471,0.0007705657,0.00014291474,0.0002626163,0.00042821316],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99676406,0.00015774835,0.00079823553,0.0011709656,0.00044133415,0.0006676488],"domain_scores_gemma":[0.99854416,0.00008594198,0.00030470183,0.0006433959,0.000026295924,0.00039549067],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026831002,0.0008940931,0.0019835706,0.0006344186,0.00011101912,0.000107317755,0.00026895653,0.00044196885,0.000112076035],"category_scores_gemma":[0.000019914769,0.0007352531,0.0005198962,0.000629856,0.00011752814,0.00007322197,0.00013890419,0.0010369391,0.0001165374],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013652076,0.0007469819,0.0004071687,0.20228773,0.0025305352,0.030342923,0.0028071932,0.000014132324,0.030585228,0.0128832385,0.0056330645,0.7116253],"study_design_scores_gemma":[0.006737797,0.0009290693,0.00008559534,0.07755494,0.015935719,0.00036580244,0.00011602665,0.0020872247,0.06382321,0.007879496,0.8199699,0.004515255],"about_ca_topic_score_codex":0.0001574058,"about_ca_topic_score_gemma":0.0000016950821,"teacher_disagreement_score":0.8143368,"about_ca_system_score_codex":0.0007286037,"about_ca_system_score_gemma":0.0005611487,"threshold_uncertainty_score":0.9995099},"labels":[],"label_agreement":null},{"id":"W4392379813","doi":"10.1101/2024.03.01.583012","title":"Assessment of Stiffness-Dependent Autophagosome Formation and Apoptosis in Embryonal Rhabdomyosarcoma Tumor Cells","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"","keywords":"Autophagy; Cell biology; Extracellular matrix; Autophagosome; Chemistry; Cancer cell; Tumor microenvironment; Apoptosis; Embryonic stem cell; Signal transduction; Programmed cell death; Cancer research; Biology; Cancer; Tumor cells; Biochemistry","score_opus":0.011475390967149923,"score_gpt":0.25640596017289513,"score_spread":0.2449305692057452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392379813","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942641,0.0028734629,0.00017573117,0.0001798941,0.0008211425,0.0010936969,0.00037031475,0.0001931337,0.000028525821],"genre_scores_gemma":[0.9971904,0.00044519026,0.0015886609,0.00019138043,0.00022224638,0.00024828815,0.0000012727505,0.00010330232,0.000009231878],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972418,0.00010401209,0.00084348,0.0007660607,0.00062700955,0.0004176422],"domain_scores_gemma":[0.99822044,0.00006499002,0.00038331878,0.0008071745,0.00024488705,0.0002792056],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050955324,0.00050910824,0.00087975495,0.0006081319,0.000052920284,0.00009800356,0.00023613233,0.00034019462,0.00009135007],"category_scores_gemma":[0.000036256817,0.0005017578,0.00018781399,0.00038869467,0.00012128109,0.00013426818,0.0004902334,0.00092080876,0.0000225206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010732957,0.00053936744,0.0042288057,0.004833382,0.0003098858,0.00025739727,0.00002761717,0.00004398276,0.98781365,0.0017487234,0.000074007614,0.00001583983],"study_design_scores_gemma":[0.0016554453,0.00011072487,0.40464607,0.0016517796,0.0003603126,1.4023018e-7,0.000010016992,0.0030763275,0.58782935,0.00004103482,0.00014518236,0.0004736092],"about_ca_topic_score_codex":0.000038204507,"about_ca_topic_score_gemma":0.0000011015209,"teacher_disagreement_score":0.40041727,"about_ca_system_score_codex":0.00039065242,"about_ca_system_score_gemma":0.0009532735,"threshold_uncertainty_score":0.9997434},"labels":[],"label_agreement":null},{"id":"W4392538177","doi":"","title":"A role for autophagic receptors in autophagosome maturation","year":2016,"lang":"fr","type":"preprint","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Autophagy; Autophagosome; Receptor; Cell biology; Neuroscience; Biology; Chemistry; Biochemistry","score_opus":0.015100750283657738,"score_gpt":0.29248716525231067,"score_spread":0.2773864149686529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392538177","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6630049,0.09475075,0.029180024,0.029959446,0.039525814,0.020374808,0.00094988046,0.0016000053,0.12065438],"genre_scores_gemma":[0.819773,0.002325251,0.0039415658,0.0018433181,0.005216676,0.0017272532,0.00058216444,0.00020390506,0.16438688],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9962255,0.00018009715,0.0010730609,0.0010904499,0.0004241285,0.0010067741],"domain_scores_gemma":[0.9977471,0.00037548825,0.0003516995,0.00091759826,0.00019356913,0.00041454227],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00060658815,0.0007155269,0.001057188,0.0003825655,0.00010722667,0.0000664038,0.00039312977,0.0010567087,0.008209741],"category_scores_gemma":[0.00019367988,0.000561044,0.0005703086,0.00023302964,0.00016795982,0.00023775316,0.00018654228,0.0005885118,0.0014759556],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0068671196,0.0032239908,0.004564388,0.0032205349,0.0017690294,0.00025260382,0.0037522388,0.00025882456,0.057897963,0.47015563,0.018311793,0.4297259],"study_design_scores_gemma":[0.021571549,0.0014583636,0.1336346,0.0073991437,0.00090752513,0.00007721339,0.00083814986,0.020670624,0.08788147,0.39057145,0.33234823,0.0026417046],"about_ca_topic_score_codex":0.00011293396,"about_ca_topic_score_gemma":0.000032263015,"teacher_disagreement_score":0.42708418,"about_ca_system_score_codex":0.0008756851,"about_ca_system_score_gemma":0.0008122892,"threshold_uncertainty_score":0.9996841},"labels":[],"label_agreement":null},{"id":"W4392538518","doi":"","title":"Role of autophagy in measles virus infection : mechanisms of autophagy induction and consequences on measles virus life cycle","year":2013,"lang":"fr","type":"preprint","venue":"theses.fr (ABES)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Autophagy; Measles virus; Measles; Virology; Virus; Biology; Medicine; Apoptosis; Vaccination; Genetics","score_opus":0.02480115117145221,"score_gpt":0.278658306390805,"score_spread":0.2538571552193528,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392538518","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97527874,0.01417174,0.00030059498,0.00021552728,0.0015636635,0.0017578473,0.00021248305,0.00015708548,0.006342319],"genre_scores_gemma":[0.98558116,0.012701701,0.0003655041,0.0002508937,0.0005268131,0.00029203936,0.00006459322,0.000117256546,0.000100048404],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99451023,0.00088509585,0.0016614309,0.0011078506,0.0010445261,0.0007908393],"domain_scores_gemma":[0.99618685,0.00051953783,0.0013133181,0.0010943643,0.00037541712,0.0005105069],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011923718,0.00094459316,0.001958617,0.00082191976,0.00015343625,0.000058937592,0.00043625978,0.0011693597,0.0019277389],"category_scores_gemma":[0.00065726874,0.00087871973,0.00040998627,0.0004917319,0.0011883529,0.00037636538,0.00032445387,0.001133583,0.00019489406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010914062,0.0023320233,0.0013833529,0.0012510594,0.0012057842,0.000055078082,0.006225139,0.002835411,0.706393,0.22687428,0.000017196158,0.05033627],"study_design_scores_gemma":[0.0023320105,0.0010863855,0.06898659,0.0027016571,0.0005822301,0.000047237423,0.0023007893,0.0026086685,0.77064943,0.14759415,0.00044129396,0.0006695433],"about_ca_topic_score_codex":0.05652721,"about_ca_topic_score_gemma":0.0010045015,"teacher_disagreement_score":0.07928012,"about_ca_system_score_codex":0.00037680884,"about_ca_system_score_gemma":0.0007385948,"threshold_uncertainty_score":0.99936634},"labels":[],"label_agreement":null},{"id":"W4392866751","doi":"10.1631/jzus.b2300402","title":"Advances in the study of mitophagy in osteoarthritis","year":2024,"lang":"en","type":"article","venue":"Journal of Zhejiang University SCIENCE B","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Shanghai University of Sport; National Natural Science Foundation of China","keywords":"Mitophagy; Osteoarthritis; Autophagy; Degeneration (medical); Mitochondrion; Medicine; Cartilage; Synovial joint; Homeostasis; Biology; Bioinformatics; Cell biology; Articular cartilage; Pathology; Internal medicine; Anatomy; Apoptosis; Genetics","score_opus":0.008885738174487784,"score_gpt":0.2829984922573953,"score_spread":0.27411275408290753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392866751","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947271,0.0030001919,0.000013514509,0.00032860372,0.00014034135,0.00010638638,7.5804724e-7,0.0000024927144,0.0016806308],"genre_scores_gemma":[0.9994728,0.00034476633,0.00004249437,0.00004160835,0.000031048035,5.37954e-8,5.478939e-8,0.0000014365519,0.0000657251],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.9992798,0.000046142046,0.00013629123,0.000078405996,0.00036439605,0.00009499471],"domain_scores_gemma":[0.9996899,0.000061009832,0.000057835445,0.000087825036,0.00006191209,0.00004155024],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005708282,0.000039275164,0.00012411413,0.00046770304,0.00003512122,0.000012357021,0.0002472778,0.000013872267,0.000017824132],"category_scores_gemma":[0.000032815788,0.000026859294,0.00004423614,0.0011377038,0.00015428019,0.0005338329,0.000018203815,0.00015382006,0.000001667397],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021495675,0.005454202,0.39725313,0.00028638623,0.0000908849,0.05128208,0.10328235,0.00062982435,0.02285787,0.0053169634,0.00052353536,0.4108732],"study_design_scores_gemma":[0.0060859793,0.0048258835,0.83846474,0.0010728254,0.00008300614,0.00049161736,0.13664034,0.00022596386,0.002163498,0.00078843406,0.009019086,0.0001386189],"about_ca_topic_score_codex":0.000021124271,"about_ca_topic_score_gemma":0.00006423985,"teacher_disagreement_score":0.4412116,"about_ca_system_score_codex":0.000068980095,"about_ca_system_score_gemma":0.0002545728,"threshold_uncertainty_score":0.10952902},"labels":[],"label_agreement":null},{"id":"W4392919168","doi":"10.3390/cells13060531","title":"Bitter Taste Receptor T2R14 and Autophagy Flux in Gingival Epithelial Cells","year":2024,"lang":"en","type":"article","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"Canadian Institutes of Health Research; CancerCare Manitoba Foundation","keywords":"Autophagy; Vacuole; Cell biology; Innate immune system; Immune system; Phagosome; Intracellular; BAG3; Biology; Chemistry; Microbiology; Apoptosis; Biochemistry; Immunology","score_opus":0.008002297368361274,"score_gpt":0.25348217413815766,"score_spread":0.24547987676979638,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392919168","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902957,0.0035883295,0.000084676874,0.00058181136,0.0013238493,0.00022256271,0.00004443086,0.00013298,0.0037256775],"genre_scores_gemma":[0.96878505,0.0002959363,0.00039060367,0.0012282601,0.00068500155,0.00001769425,0.00002454568,0.000048605576,0.028524293],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989719,0.00003761528,0.00021487006,0.0003342679,0.00016234007,0.0002790329],"domain_scores_gemma":[0.99951863,0.00007013901,0.00002129098,0.00021522366,0.000016192786,0.00015854856],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00014521417,0.00016877061,0.00024214626,0.00015682669,0.000029270092,0.00004562884,0.0000657427,0.0001047821,0.0021879398],"category_scores_gemma":[0.000005473616,0.00014076027,0.0000868054,0.00017910163,0.00007442137,0.000077758705,0.000035836838,0.0002223284,0.0013593478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011873298,0.00010909797,0.000122016485,0.0002663125,0.00007137719,0.0005502754,0.0011976105,0.000005173748,0.9588712,0.00017578136,0.018696701,0.019815713],"study_design_scores_gemma":[0.0010857048,0.00014668421,0.0010898996,0.00021641693,0.000055591936,0.000017817221,0.00009758875,0.0007416045,0.81149584,0.00029362997,0.1845804,0.00017879871],"about_ca_topic_score_codex":0.000018579027,"about_ca_topic_score_gemma":0.000001395482,"teacher_disagreement_score":0.16588369,"about_ca_system_score_codex":0.000044959255,"about_ca_system_score_gemma":0.0000981519,"threshold_uncertainty_score":0.9994182},"labels":[],"label_agreement":null},{"id":"W4392989411","doi":"10.1038/s41416-024-02660-4","title":"Retraction Note: Effect of pantoprazole to enhance activity of docetaxel against human tumour xenografts by inhibiting autophagy","year":2024,"lang":"en","type":"retraction","venue":"British Journal of Cancer","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":true,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Toronto Rehabilitation Institute; University of Toronto; University Health Network","funders":"","keywords":"Docetaxel; Autophagy; Medicine; Pantoprazole; Cancer research; Pharmacology; Oncology; Internal medicine; Chemotherapy; Biology; Apoptosis; Biochemistry","score_opus":0.007665110844710987,"score_gpt":0.35716640631994345,"score_spread":0.34950129547523245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392989411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8949833,0.09870786,0.00009880436,0.00014034047,0.0034807401,0.00050237076,0.0004298222,0.00003129684,0.0016254915],"genre_scores_gemma":[0.95618474,0.03805001,0.000046364898,0.00010495007,0.00315219,0.000024386034,0.00005398002,0.00009785083,0.0022855473],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969264,0.0001717802,0.0010893214,0.00034789953,0.0011364951,0.0003280566],"domain_scores_gemma":[0.99704325,0.00014585565,0.0018198304,0.00017804148,0.0005531028,0.00025990157],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000901832,0.0003493525,0.0014506811,0.00038592776,0.00008755546,0.000054776676,0.00017427148,0.0006224931,0.00025051605],"category_scores_gemma":[0.00021348716,0.00036258242,0.0006751028,0.00041591105,0.000088390385,0.00029267368,0.000038217615,0.0021167628,0.0000066001803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071893824,0.00023566461,0.000051343803,0.0027969384,0.0006387383,0.00063156337,0.00006877839,0.000015677713,0.5309737,5.821797e-7,0.04204912,0.42181894],"study_design_scores_gemma":[0.0013398237,0.0013213597,0.0036719597,0.022085799,0.0010443055,0.000713051,0.000011866909,0.000017421655,0.9279255,0.000013690019,0.041566625,0.00028855886],"about_ca_topic_score_codex":0.000758384,"about_ca_topic_score_gemma":0.00010513849,"teacher_disagreement_score":0.4215304,"about_ca_system_score_codex":0.00050810527,"about_ca_system_score_gemma":0.0005685762,"threshold_uncertainty_score":0.99988264},"labels":[],"label_agreement":null},{"id":"W4393095274","doi":"10.1080/27694127.2024.2330327","title":"Impaired autophagy flux contributes to enhanced ischemia reperfusion injury in the diabetic heart","year":2024,"lang":"en","type":"article","venue":"Autophagy Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto; York University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Autophagy; Propidium iodide; Programmed cell death; Apoptosis; Chemistry; Streptozotocin; Flow cytometry; Blot; Viability assay; Annexin; Molecular biology; Ischemia; Cell biology; Biology; Medicine; Internal medicine; Endocrinology; Biochemistry; Diabetes mellitus","score_opus":0.007961363052263389,"score_gpt":0.29387289005676664,"score_spread":0.28591152700450323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393095274","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98580277,0.0050899955,0.00014418454,0.0038947326,0.0011041668,0.0013089747,0.000008892176,0.00045354085,0.002192721],"genre_scores_gemma":[0.9892132,0.000059590537,0.00015404291,0.006006128,0.0003184914,0.0003531049,0.00007212678,0.00006480677,0.003758475],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99695796,0.00012353247,0.0008912539,0.00083373184,0.00056132313,0.00063219096],"domain_scores_gemma":[0.9981998,0.00019878855,0.00010237857,0.0011546781,0.00010368221,0.00024062888],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010516032,0.00036789253,0.0006264384,0.00031696665,0.0001306039,0.00012320837,0.00017709368,0.0002344081,0.00065618736],"category_scores_gemma":[0.00036007483,0.0002588827,0.0003084751,0.0010440112,0.000100538375,0.00016274916,0.00009553596,0.00046641915,0.0002513368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024540903,0.0004217439,0.0026918403,0.00021021407,0.00018632901,0.008731317,0.0017407227,0.00001422576,0.93526024,0.0004812406,0.038190868,0.011825883],"study_design_scores_gemma":[0.00057546055,0.0003830715,0.042500257,0.0005858343,0.0001485912,0.0008244415,0.00010063157,0.0002992916,0.9106115,0.0021283012,0.04154082,0.00030178117],"about_ca_topic_score_codex":0.000059600712,"about_ca_topic_score_gemma":0.000002956674,"teacher_disagreement_score":0.039808415,"about_ca_system_score_codex":0.00019037911,"about_ca_system_score_gemma":0.00047558863,"threshold_uncertainty_score":0.99998635},"labels":[],"label_agreement":null},{"id":"W4393098017","doi":"10.1111/cts.13758","title":"Ischemia‐induced cardiac dysfunction is exacerbated in adiponectin‐knockout mice due to impaired autophagy flux","year":2024,"lang":"en","type":"article","venue":"Clinical and Translational Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Autophagy; Adiponectin; Knockout mouse; Medicine; Cardiac dysfunction; Flux (metallurgy); Ischemia; Internal medicine; Myocardial ischemia; Cardiology; Biology; Heart failure; Obesity; Chemistry; Apoptosis; Genetics","score_opus":0.040186949750198285,"score_gpt":0.3674862841051378,"score_spread":0.3272993343549395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393098017","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99206257,0.0013108327,0.00020174803,0.003790257,0.00061023893,0.0003134184,0.000019456893,0.000087649576,0.0016038247],"genre_scores_gemma":[0.9975136,0.00003815943,0.00029659603,0.0011636786,0.00025297236,0.000020012501,0.0000151592485,0.0000102975255,0.0006895035],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99835896,0.00004020271,0.00039974108,0.0005676436,0.00038377117,0.00024965627],"domain_scores_gemma":[0.999146,0.0002615808,0.000022645205,0.00014519486,0.00008118083,0.0003434306],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008775596,0.00012771173,0.00026666548,0.00015483733,0.00011265125,0.00004800487,0.00009036547,0.00011155348,0.00034996515],"category_scores_gemma":[0.000121587,0.000103541686,0.00012830703,0.00094578846,0.00029926875,0.00022028717,0.000018906714,0.00025060418,0.00014759741],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020931342,0.0010839069,0.09226421,0.0003350771,0.0004046274,0.0005099037,0.004691989,0.00005112022,0.44570884,0.0055542937,0.0042293197,0.44307357],"study_design_scores_gemma":[0.0012073355,0.0002964792,0.9547133,0.0001787041,0.00008153156,0.000030665033,0.00004522448,0.005809536,0.029983232,0.0017815743,0.00567592,0.00019649003],"about_ca_topic_score_codex":0.000046992467,"about_ca_topic_score_gemma":0.00000590986,"teacher_disagreement_score":0.8624491,"about_ca_system_score_codex":0.000023395865,"about_ca_system_score_gemma":0.00047389837,"threshold_uncertainty_score":0.42223072},"labels":[],"label_agreement":null},{"id":"W4393236772","doi":"10.1016/j.jtherbio.2024.103831","title":"Impaired autophagy following ex vivo cooling of simulated hypothermic temperatures in peripheral blood mononuclear cells from young and older adults","year":2024,"lang":"en","type":"article","venue":"Journal of Thermal Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Peripheral blood mononuclear cell; Ex vivo; Hypothermia; Medicine; Apoptosis; Hsp70; Inflammation; Heat shock protein; Programmed cell death; Cytoprotection; Immune system; In vivo; Immunology; Andrology; Biology; Endocrinology; Internal medicine; Oxidative stress; In vitro; Biochemistry","score_opus":0.0056951317167722735,"score_gpt":0.2534812359890239,"score_spread":0.24778610427225162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393236772","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97946537,0.019710336,0.00000725484,0.00007033812,0.0005041486,0.00015110735,0.00001943079,0.000023266979,0.00004874722],"genre_scores_gemma":[0.9988816,0.00035189386,0.00019081052,0.00018985309,0.00028696688,7.6076896e-7,0.000004014289,0.000033647964,0.00006048204],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988199,0.000120039054,0.0005393108,0.00019046738,0.000110762936,0.00021951334],"domain_scores_gemma":[0.999417,0.00013763638,0.00016119958,0.00012851518,0.00004969228,0.000105951265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020449448,0.00017794562,0.0005443537,0.00018254135,0.000026625565,0.00001966499,0.000111206275,0.0001897097,0.00029508994],"category_scores_gemma":[0.00002819878,0.00012760576,0.00025305944,0.0001257653,0.00006988816,0.00009873594,0.000027608467,0.00034738306,0.00000242014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016696502,0.00018690951,0.0079750465,0.00006061849,0.0007758593,0.001204553,0.002307688,0.00015644626,0.98363,0.0000091530865,0.000025930614,0.0019981146],"study_design_scores_gemma":[0.020062162,0.0030819564,0.2846406,0.003686718,0.0012011183,0.00074616744,0.0013354481,0.015584353,0.66826767,0.0005515579,0.00023626002,0.00060598715],"about_ca_topic_score_codex":0.00011985058,"about_ca_topic_score_gemma":0.0000034309915,"teacher_disagreement_score":0.31536236,"about_ca_system_score_codex":0.000033675013,"about_ca_system_score_gemma":0.00010044232,"threshold_uncertainty_score":0.5203612},"labels":[],"label_agreement":null},{"id":"W4393276581","doi":"10.1101/2024.03.27.587008","title":"Identification of stress specific autophagy regulators from tandem CRISPR screens","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto; Ottawa Hospital Research Institute; Canadian Institutes of Health Research; University of Ottawa","keywords":"CRISPR; Autophagy; Identification (biology); Computational biology; Tandem; Biology; Computer science; Genetics; Engineering; Gene; Ecology","score_opus":0.01439446249010415,"score_gpt":0.2500948410239656,"score_spread":0.23570037853386147,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393276581","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97673655,0.017014321,0.00084716605,0.00020812395,0.0020942113,0.0009609982,0.0015396101,0.0005754857,0.000023551924],"genre_scores_gemma":[0.99627936,0.0011340283,0.0008340145,0.00011398814,0.0012663956,0.000113674905,0.000005617168,0.00021183328,0.000041064577],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962748,0.00011234743,0.0011218236,0.0012781275,0.0007603296,0.0004525303],"domain_scores_gemma":[0.9961197,0.00007005258,0.00064605917,0.0022438003,0.00054245663,0.0003779418],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041275422,0.00062671717,0.00097312726,0.00044316534,0.000091601454,0.00013659525,0.00048110652,0.00073641137,0.0002790707],"category_scores_gemma":[0.00008764076,0.0006395767,0.000432177,0.0005698049,0.00022632368,0.00008720268,0.00041579362,0.00094497076,0.00018495468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013005409,0.00042896857,0.006030473,0.0010377611,0.0010709122,0.0002820145,0.000034552617,0.000031166015,0.98689264,0.0023567686,0.0016923372,0.000012346686],"study_design_scores_gemma":[0.00061075593,0.000044934022,0.26056933,0.0011448917,0.00058889814,1.7290313e-8,0.000007733247,0.00039997647,0.7348448,0.00007617634,0.0012696252,0.00044285288],"about_ca_topic_score_codex":0.00008505048,"about_ca_topic_score_gemma":0.0000013275068,"teacher_disagreement_score":0.25453886,"about_ca_system_score_codex":0.00030138344,"about_ca_system_score_gemma":0.00073136395,"threshold_uncertainty_score":0.99960554},"labels":[],"label_agreement":null},{"id":"W4393289847","doi":"10.1016/j.jksus.2024.103180","title":"The angiotensin II type 1 receptor mediates the induction of oxidative stress, apoptosis, and autophagy in HUVECs induced by angiotensin II","year":2024,"lang":"en","type":"article","venue":"Journal of King Saud University - Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Deanship of Scientific Research, Imam Mohammed Ibn Saud Islamic University","keywords":"Autophagy; Angiotensin II; Losartan; Oxidative stress; Apoptosis; Cell biology; Reactive oxygen species; Annexin; Chemistry; Receptor; Biology; Endocrinology; Biochemistry","score_opus":0.01361645963114911,"score_gpt":0.25684154705491086,"score_spread":0.24322508742376175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393289847","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99201936,0.0022573806,0.000015415442,0.00506127,0.00047390204,0.00009281797,0.000005960185,0.000009714268,0.00006415869],"genre_scores_gemma":[0.9984985,0.00093869754,0.00022575034,0.00008600568,0.00008885249,4.4479393e-8,0.0000011470075,0.0000049458167,0.00015603553],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989999,0.00007080849,0.0001860855,0.00014874846,0.0004244044,0.00017006528],"domain_scores_gemma":[0.99914277,0.00014653851,0.00019280605,0.00013490801,0.00028894749,0.00009402754],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00078957085,0.0000891937,0.00017303163,0.00024415497,0.00049381406,0.000035710465,0.00024324813,0.00005347379,0.000012416063],"category_scores_gemma":[0.00019701816,0.00005412508,0.00006177571,0.0011033718,0.00059246505,0.00038550285,0.00011033306,0.0003311374,6.586422e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031755172,0.0001283975,0.0013710945,0.000014903049,0.00012521555,0.000040843603,0.0064277938,0.000019737185,0.975143,0.0009480325,0.0031021335,0.012361288],"study_design_scores_gemma":[0.0019697759,0.002042045,0.123155445,0.0015291086,0.0003587498,0.0001468497,0.0123862475,0.0012698617,0.83799696,0.00083495415,0.017997583,0.00031243206],"about_ca_topic_score_codex":0.00009995258,"about_ca_topic_score_gemma":0.00001144493,"teacher_disagreement_score":0.13714606,"about_ca_system_score_codex":0.00014837603,"about_ca_system_score_gemma":0.000492671,"threshold_uncertainty_score":0.37980685},"labels":[],"label_agreement":null},{"id":"W4393344556","doi":"10.1101/2024.03.28.587227","title":"The ER-phagy receptor FAM134B is targeted by <i>Salmonella</i> Typhimurium to promote infection","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Ottawa Hospital Research Institute; University of Ottawa","keywords":"Autophagy; Endoplasmic reticulum; Salmonella enterica; Salmonella; Biology; Cell biology; Bacteria; Genetics","score_opus":0.008743147887869517,"score_gpt":0.23919236391811477,"score_spread":0.23044921603024526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393344556","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96865344,0.014067894,0.0002215785,0.0077325827,0.0046528853,0.0026367542,0.0007123418,0.0012470314,0.00007550588],"genre_scores_gemma":[0.98975635,0.0023491909,0.0006346876,0.0042677205,0.0015683416,0.0007158442,0.0000036863696,0.0003553734,0.00034881686],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963721,0.00012746244,0.0006975192,0.0013343435,0.0006724536,0.0007960967],"domain_scores_gemma":[0.9966419,0.000057685804,0.00028320384,0.0017893388,0.0005578607,0.00067003164],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00060313096,0.00079047703,0.00071840826,0.0002559804,0.00032367208,0.00033207747,0.00044187056,0.00072978507,0.0002490635],"category_scores_gemma":[0.00017791284,0.0006429496,0.00038112246,0.00090148405,0.00013710516,0.00007439936,0.00057758525,0.0014410368,0.0016122995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002863098,0.00030352664,0.000723716,0.00074083457,0.000925051,0.00008234532,0.00004218543,0.000005866361,0.8276094,0.00022813564,0.16901805,0.00003454478],"study_design_scores_gemma":[0.0005116693,0.00018859272,0.0042627696,0.0005235846,0.00036010615,4.6059252e-8,0.0000018161516,0.0001131836,0.6114387,0.00001668851,0.3819773,0.0006055842],"about_ca_topic_score_codex":0.0000923149,"about_ca_topic_score_gemma":0.0000012750519,"teacher_disagreement_score":0.21617076,"about_ca_system_score_codex":0.00047249527,"about_ca_system_score_gemma":0.0008719486,"threshold_uncertainty_score":0.9996022},"labels":[],"label_agreement":null},{"id":"W4393352921","doi":"10.3390/ijms25073913","title":"Protein Disulfide Isomerase 4 Is an Essential Regulator of Endothelial Function and Survival","year":2024,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Heart and Stroke Foundation of Canada","keywords":"Autophagy; Endothelial stem cell; Cell biology; Regulator; Endothelial dysfunction; Protein disulfide-isomerase; Biology; Vascular endothelial growth factor B; Vascular endothelial growth factor A; Chemistry; Apoptosis; Biochemistry; Cancer research; Vascular endothelial growth factor; In vitro; Endocrinology; Endoplasmic reticulum","score_opus":0.012673711355657438,"score_gpt":0.3094007302801079,"score_spread":0.29672701892445047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393352921","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922697,0.0018645036,0.0037085547,0.0011864839,0.00072668144,0.00006306822,0.00001174784,0.0000070818123,0.00016220946],"genre_scores_gemma":[0.9988705,0.00007083872,0.00049248483,0.00018024615,0.00031140703,0.0000011119071,0.0000013434243,0.0000055202113,0.000066569315],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880207,0.00003507569,0.00024237273,0.00012166836,0.00072870497,0.000070107395],"domain_scores_gemma":[0.9995465,0.000018496796,0.000109280336,0.000055621163,0.00018709512,0.00008296106],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033765752,0.000063799605,0.0001171695,0.00020128446,0.0000258777,0.00006611972,0.00014711924,0.000026126614,0.00014175943],"category_scores_gemma":[0.000032613098,0.00004633302,0.000094936106,0.00010931682,0.0001883441,0.00026165915,0.000020097255,0.00007771058,0.000001900859],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047393158,0.00015794033,0.0010780774,0.000024184197,0.00029931258,0.00039357826,0.0002813926,0.000019840098,0.9715151,0.00964587,0.00003780823,0.01607293],"study_design_scores_gemma":[0.0018810845,0.0017480262,0.014057607,0.0006222075,0.00017176756,0.00057489204,0.00037192064,0.0021729881,0.95647717,0.020391801,0.001384727,0.00014580494],"about_ca_topic_score_codex":0.000014727396,"about_ca_topic_score_gemma":7.8494327e-7,"teacher_disagreement_score":0.015927127,"about_ca_system_score_codex":0.000016221851,"about_ca_system_score_gemma":0.00021303543,"threshold_uncertainty_score":0.18894058},"labels":[],"label_agreement":null},{"id":"W4393397077","doi":"10.1038/s41598-024-58285-3","title":"Identification and structural characterization of small molecule inhibitors of PINK1","year":2024,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Structural Genomics Consortium","funders":"National Institute of Neurological Disorders and Stroke; Office of Science; National Institutes of Health; Canadian Institutes of Health Research; Parkinson Canada; U.S. Department of Energy; McGill University; Argonne National Laboratory; Fonds de Recherche du Québec - Santé; Michael J. Fox Foundation for Parkinson's Research","keywords":"PINK1; Parkin; Cell biology; Ubiquitin ligase; Autophosphorylation; Ubiquitin; Mitophagy; Mitochondrion; Organelle; Biology; Phosphorylation; Kinase; Biochemistry; Chemistry; Protein kinase A; Autophagy; Parkinson's disease; Medicine","score_opus":0.009320992698905855,"score_gpt":0.26102502556508955,"score_spread":0.2517040328661837,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393397077","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968306,0.00058936485,0.00014433356,0.000070338574,0.0020449068,0.00020591267,0.0000050753783,0.00003045234,0.00007903065],"genre_scores_gemma":[0.9988066,0.000013737621,0.00002464086,0.0000069198354,0.00004311822,0.0000043769237,0.000121271354,0.000008073496,0.0009712607],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990689,0.000012128318,0.00037430273,0.0002666086,0.00020657349,0.000071455885],"domain_scores_gemma":[0.99939257,0.0000055137443,0.0001632142,0.0002785073,0.00011132207,0.00004887283],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028423933,0.00005926639,0.00012205501,0.00015085512,0.000035149227,0.00004312415,0.000022445998,0.000035263547,0.000063265674],"category_scores_gemma":[0.00002157564,0.000048566377,0.00005141779,0.0002780097,0.0001516567,0.00008941879,0.000015556558,0.000037006845,0.0000016929564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007714345,0.0000148402005,0.0031067787,0.00022755498,0.000024719957,0.00006497452,0.00035899936,4.7024977e-7,0.9910594,0.00011619961,0.000086235326,0.0049320688],"study_design_scores_gemma":[0.000069462294,0.00002556743,0.055443447,0.00013334268,0.000050621187,0.000093333234,0.00003335897,0.00044207537,0.9420054,0.0012683532,0.0003914849,0.00004353353],"about_ca_topic_score_codex":0.000005785614,"about_ca_topic_score_gemma":7.091791e-7,"teacher_disagreement_score":0.052336667,"about_ca_system_score_codex":0.00001073595,"about_ca_system_score_gemma":0.00009951971,"threshold_uncertainty_score":0.19804795},"labels":[],"label_agreement":null},{"id":"W4393910131","doi":"10.1016/j.neo.2024.100994","title":"Retraction notice to “Role of Autophagy as a Survival Mechanism for Hypoxic Cells in Tumors” [Neoplasia 18 (2016) 347- 355/201]","year":2024,"lang":"en","type":"article","venue":"Neoplasia","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":true,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Notice; Autophagy; Mechanism (biology); Cancer research; Hypoxia (environmental); Medicine; Biology; Pathology; Cell biology; Chemistry; Philosophy; Genetics; Political science; Oxygen; Apoptosis; Law; Epistemology","score_opus":0.012595217939620724,"score_gpt":0.29137819405856075,"score_spread":0.27878297611894004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393910131","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9846889,0.00067307166,0.0011623971,0.0005829625,0.0024117704,0.0013758072,0.000101079495,0.00023527835,0.008768764],"genre_scores_gemma":[0.99268866,0.00008795966,0.0012808953,0.0005741437,0.0005227921,0.00014674618,0.000038284645,0.0000895463,0.004570963],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99785155,0.000071750124,0.00054505473,0.0005708223,0.0004755982,0.00048522622],"domain_scores_gemma":[0.99866194,0.00035395168,0.00010445835,0.00045031065,0.00014069962,0.00028861666],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041325588,0.000303716,0.00055736164,0.0004070649,0.00005772038,0.00004158059,0.00016800487,0.00032952835,0.00073920423],"category_scores_gemma":[0.00017741013,0.00028749977,0.00023542697,0.000517741,0.000039094586,0.000176062,0.00003958581,0.00039798286,0.0006489529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003143456,0.00095989514,0.0003441081,0.001141025,0.00039051843,0.0008093413,0.0026489021,0.00009221907,0.92277724,0.038460135,0.00917176,0.020061377],"study_design_scores_gemma":[0.0033731696,0.0020466757,0.008747202,0.0009883498,0.00034925574,0.00023555288,0.0009582793,0.0049403384,0.9342531,0.016015675,0.027566912,0.0005254746],"about_ca_topic_score_codex":0.00020269695,"about_ca_topic_score_gemma":0.000074215845,"teacher_disagreement_score":0.022444459,"about_ca_system_score_codex":0.00016531041,"about_ca_system_score_gemma":0.00052422506,"threshold_uncertainty_score":0.99995774},"labels":[{"model":"gemma","categories":["research_integrity"],"domain":null,"study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"high"},{"model":"gpt","categories":["metaresearch","research_integrity"],"domain":"methods","study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"high"}],"label_agreement":"split"},{"id":"W4393950309","doi":"10.1016/j.stemcr.2024.03.004","title":"PINK1 deficiency alters muscle stem cell fate decision and muscle regenerative capacity","year":2024,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Ottawa Hospital Research Institute; Canadian Institutes of Health Research; University of Ottawa","keywords":"Mitophagy; PINK1; Biology; Cell biology; Mitochondrion; Parkin; Stem cell; Regeneration (biology); Regulator; Cell fate determination; Autophagy; Genetics; Apoptosis; Gene; Internal medicine","score_opus":0.019399359712128268,"score_gpt":0.25691690382126847,"score_spread":0.2375175441091402,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393950309","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.970906,0.013485652,0.00093216926,0.00007544375,0.00092984695,0.00051131786,0.0000127914755,0.00018758552,0.012959178],"genre_scores_gemma":[0.99388266,0.00046611245,0.00029172553,0.00019473914,0.00014599477,0.00002784237,0.000013550747,0.000048680373,0.0049287155],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978822,0.000058464113,0.0005283778,0.0007273662,0.00045239553,0.00035121542],"domain_scores_gemma":[0.99877775,0.00009566712,0.00015292653,0.0005874531,0.000085115156,0.0003010876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038968385,0.00026562286,0.00034205324,0.00013729437,0.00016032846,0.00008476497,0.000061339226,0.00012828596,0.00012057938],"category_scores_gemma":[0.0000054794486,0.00021153847,0.00015939433,0.00026020492,0.00009726158,0.00015391572,0.000058982354,0.00022490964,0.000051869793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029920685,0.0010719439,0.0041999803,0.0025423847,0.00019292277,0.032320354,0.012744664,0.00018867658,0.54097474,0.00058874453,0.0138842035,0.3909922],"study_design_scores_gemma":[0.0022013488,0.0014574481,0.032966103,0.0014390203,0.0006825337,0.0015392532,0.0032391371,0.0025591827,0.87223786,0.0026607988,0.07769259,0.0013247237],"about_ca_topic_score_codex":0.00004291073,"about_ca_topic_score_gemma":0.0000053858034,"teacher_disagreement_score":0.38966748,"about_ca_system_score_codex":0.00010334623,"about_ca_system_score_gemma":0.00018088084,"threshold_uncertainty_score":0.8626288},"labels":[],"label_agreement":null},{"id":"W4393978647","doi":"10.1007/7651_2024_531","title":"Characterization of Bitter Taste Receptor-Dependent Autophagy in Oral Epithelial Cells","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research Institute in Oncology and Hematology; University of Manitoba; CancerCare Manitoba; Research Manitoba","funders":"","keywords":"Autophagy; Cell biology; Receptor; Innate immune system; Biology; Immune system; Flow cytometry; Acridine orange; Immunology; Biochemistry; Apoptosis","score_opus":0.018250884738470488,"score_gpt":0.38257182545890084,"score_spread":0.36432094072043036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393978647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7108755,0.00066599593,0.28721896,0.0001926019,0.000609423,0.0001971878,0.000028923336,0.000030126866,0.0001812888],"genre_scores_gemma":[0.65719616,0.00047516022,0.33914265,0.0017368392,0.00019988655,0.00010442699,0.00024074112,0.00007911876,0.0008249923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982353,0.00076005916,0.00038647244,0.00031943203,0.00007879513,0.00021998014],"domain_scores_gemma":[0.9995684,0.000075802534,0.000053904943,0.0002293147,0.000024969291,0.00004760234],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00078590785,0.00014101606,0.00037264827,0.00034646,0.000007506043,0.00000617009,0.00009277792,0.00020499637,0.00035401137],"category_scores_gemma":[0.000054335847,0.000120381075,0.000098479715,0.0003259188,0.00008088271,0.000026367192,0.000043978293,0.00021927034,0.000027250982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011696205,0.000090567606,0.00039272098,0.0000733692,0.00004900405,0.0001605361,0.00017416892,0.000004439297,0.9513043,0.0012112199,0.0000037683342,0.046418913],"study_design_scores_gemma":[0.0007126262,0.00019693915,0.002141983,0.00007777648,0.000025244417,0.000010522801,0.000011182506,0.00048578597,0.9907408,0.0016467932,0.003847558,0.000102811544],"about_ca_topic_score_codex":0.000028769664,"about_ca_topic_score_gemma":0.0000017868731,"teacher_disagreement_score":0.05367933,"about_ca_system_score_codex":0.000052187406,"about_ca_system_score_gemma":0.000079898986,"threshold_uncertainty_score":0.49089977},"labels":[],"label_agreement":null},{"id":"W4394010197","doi":"10.1016/j.canlet.2024.216861","title":"TRAF6 enhances PD-L1 expression through YAP1-TFCP2 signaling in melanoma","year":2024,"lang":"en","type":"article","venue":"Cancer Letters","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"","keywords":"YAP1; Immune checkpoint; Cancer research; Melanoma; Ubiquitin ligase; Biology; PD-L1; Bortezomib; Cell biology; Ubiquitin; Immune system; Immunotherapy; Chemistry; Transcription factor; Immunology; Biochemistry","score_opus":0.01938222906358627,"score_gpt":0.3220906302003597,"score_spread":0.30270840113677344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394010197","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9727977,0.018315373,0.00054978265,0.006329127,0.00069033727,0.00020605592,0.000008967798,0.0001239409,0.0009787476],"genre_scores_gemma":[0.9879137,0.00062813587,0.000228135,0.010009558,0.00071775843,0.00011206338,0.000012348863,0.000030647996,0.0003476531],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990211,0.000029652863,0.00019403727,0.00030959188,0.00019553106,0.00025009716],"domain_scores_gemma":[0.9996709,0.00005091296,0.000027772136,0.0001719173,0.000011593897,0.000066868546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007052367,0.0001475357,0.00021191535,0.00007642325,0.000037199225,0.000032370805,0.00008628783,0.00006232515,0.0008993846],"category_scores_gemma":[0.0000063786715,0.00011796789,0.00010036176,0.00020282481,0.000058378384,0.00018719476,0.000013686692,0.00020670013,0.000064483844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016533566,0.00003640502,0.0009768525,0.00021248331,0.00007268082,0.0005334723,0.0025366084,0.00008401922,0.9763664,0.00007240913,0.012318803,0.0066245506],"study_design_scores_gemma":[0.0009402921,0.00006515772,0.003195338,0.0018789505,0.00006996729,0.000010991508,0.0001596874,0.00016981886,0.9429491,0.00028499163,0.050053008,0.00022266146],"about_ca_topic_score_codex":0.00006297063,"about_ca_topic_score_gemma":0.0000059243,"teacher_disagreement_score":0.037734203,"about_ca_system_score_codex":0.00012344363,"about_ca_system_score_gemma":0.00008843965,"threshold_uncertainty_score":0.9847631},"labels":[],"label_agreement":null},{"id":"W4394076777","doi":"10.6084/m9.figshare.22127853.v1","title":"Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1","year":2023,"lang":"en","type":"dataset","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Memorial University of Newfoundland; University of Toronto","funders":"","keywords":"Mitophagy; Hypoxia (environmental); VDAC1; Ubiquitin; Cell biology; Chemistry; Biology; Autophagy; Biochemistry; Apoptosis; Gene; Oxygen","score_opus":0.04331431926061793,"score_gpt":0.31150781693523405,"score_spread":0.26819349767461614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394076777","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002124023,0.00044499623,4.821949e-7,0.00005334257,0.00029455972,0.0010649952,0.99568194,0.00021958734,0.00011604482],"genre_scores_gemma":[0.0041672993,0.000043195992,0.000023065648,0.00018848616,0.0008277908,0.0003176305,0.9941139,0.00009333179,0.00022524917],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99736327,0.00010993578,0.0007739699,0.00054401834,0.0008121073,0.0003967085],"domain_scores_gemma":[0.99726886,0.0004896991,0.0008559955,0.00075852475,0.00041018456,0.0002167449],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00012381493,0.00043423905,0.000740356,0.00048952363,0.000104134415,0.000028070282,0.00028057402,0.0007591271,0.029438697],"category_scores_gemma":[0.002758518,0.00043032173,0.00031600942,0.0007124195,0.000014791854,0.00013209498,0.000099869096,0.000497444,0.0048587685],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001174029,0.000119278935,0.0000030224169,0.0018058196,0.00021219104,0.00013321705,0.00003071163,0.00000560799,0.0016133713,2.9447483e-7,0.9931814,0.0027776626],"study_design_scores_gemma":[0.0058090393,0.00089725043,0.013107491,0.017964548,0.0006637912,0.00007006895,0.00008057334,0.001493872,0.029922947,0.00011486142,0.9285822,0.0012933747],"about_ca_topic_score_codex":0.0000824343,"about_ca_topic_score_gemma":0.000022272308,"teacher_disagreement_score":0.06459924,"about_ca_system_score_codex":0.00016287068,"about_ca_system_score_gemma":0.0004073854,"threshold_uncertainty_score":0.99981487},"labels":[],"label_agreement":null},{"id":"W4394130217","doi":"10.6084/m9.figshare.22620187","title":"Additional file 5 of Human menstrual blood-derived stem cells reverse sorafenib resistance in hepatocellular carcinoma cells through the hyperactivation of mitophagy","year":2023,"lang":"en","type":"dataset","venue":"Open MIND","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Hepatocellular carcinoma; Mitophagy; Sorafenib; Hyperactivation; Cancer research; Stem cell; Medicine; Internal medicine; Biology; Cell biology; Autophagy; Genetics; Apoptosis","score_opus":0.04212877943146319,"score_gpt":0.29246868698575684,"score_spread":0.25033990755429364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394130217","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.060029555,0.000109193505,1.2898501e-7,0.000030986324,0.00011445918,0.0010651621,0.93825555,0.0000019352278,0.00039303565],"genre_scores_gemma":[0.0019069744,0.000051743133,0.00044202167,0.0000590928,0.00015641218,0.00024226937,0.99116266,0.00003651822,0.00594234],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99784327,0.00017777251,0.0007321389,0.00048783346,0.0005151251,0.00024385037],"domain_scores_gemma":[0.9973011,0.0008419027,0.0007714245,0.00087151414,0.0001476495,0.00006641196],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001543759,0.00030517142,0.00074135314,0.00012143986,0.00009501453,0.000023703093,0.0005843569,0.00027674995,0.26901135],"category_scores_gemma":[0.00005371598,0.0002536187,0.00017692444,0.0003461243,0.00017842527,0.00014212295,0.00017690186,0.0003924569,0.0005648922],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026845548,0.00079406577,0.000003109865,0.00019521506,0.00020396108,0.0003149449,0.00020110584,7.478243e-7,0.011830426,0.0000019782426,0.9861151,0.00007090478],"study_design_scores_gemma":[0.002598804,0.00016368894,0.00027396178,0.0011503203,0.0002250089,0.000004395971,0.00048020322,0.0000032888238,0.13547955,0.000043058335,0.8593596,0.0002181197],"about_ca_topic_score_codex":0.00054108707,"about_ca_topic_score_gemma":0.00025388537,"teacher_disagreement_score":0.26844645,"about_ca_system_score_codex":0.000062929306,"about_ca_system_score_gemma":0.0004943303,"threshold_uncertainty_score":0.9999916},"labels":[],"label_agreement":null},{"id":"W4394168105","doi":"10.6084/m9.figshare.16441371","title":"C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy","year":2021,"lang":"en","type":"dataset","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Mitophagy; Component (thermodynamics); Stability (learning theory); Cell biology; Chemistry; Biology; Computer science; Genetics; Physics; Autophagy; Machine learning","score_opus":0.039362915037621224,"score_gpt":0.28088763827206603,"score_spread":0.2415247232344448,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394168105","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007232592,0.0054583396,4.2824075e-7,0.0001428836,0.000038613838,0.00071035983,0.98638797,0.000014070726,0.00001475285],"genre_scores_gemma":[0.030412158,0.00020411277,0.0000038455655,0.00071374176,0.000105329855,0.00007591852,0.96845144,0.000016896125,0.00001653023],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987652,0.00010033666,0.00032301797,0.0003496763,0.00029410073,0.00016771708],"domain_scores_gemma":[0.9987515,0.00011262903,0.00022909357,0.00062514795,0.00015818582,0.00012343047],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000038240745,0.00023378445,0.00054633955,0.00004272527,0.00010864432,0.000028174147,0.00012434745,0.00019324821,0.058747854],"category_scores_gemma":[0.00027316285,0.00017334272,0.00012208868,0.00010804124,0.000047827292,0.000037184018,0.00020455735,0.00022322271,0.000017280629],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011516824,0.00012572952,0.00017094835,0.0029940992,0.00015827545,0.000035696998,0.000062876614,8.3023184e-7,0.00047949026,3.1409266e-7,0.9957522,0.00010434736],"study_design_scores_gemma":[0.003313677,0.0000855091,0.08152701,0.004838111,0.00024315409,0.000046902456,0.00007039735,0.00024153585,0.0067705563,0.000018774806,0.90257615,0.00026820923],"about_ca_topic_score_codex":0.000038572896,"about_ca_topic_score_gemma":0.000014242137,"teacher_disagreement_score":0.09317606,"about_ca_system_score_codex":0.000039175426,"about_ca_system_score_gemma":0.00011080053,"threshold_uncertainty_score":0.94211257},"labels":[],"label_agreement":null},{"id":"W4394171071","doi":"10.6084/m9.figshare.13186899","title":"Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3","year":2021,"lang":"en","type":"dataset","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Optineurin; Autophagy; Mesenchymal stem cell; Cell biology; Balance (ability); Receptor; Biology; Neuroscience; Biochemistry","score_opus":0.014013133738959191,"score_gpt":0.24758034781170066,"score_spread":0.23356721407274147,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394171071","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.023999836,0.0193756,5.0364267e-8,0.00007776991,0.00018673179,0.0004585465,0.95561886,0.0001706996,0.00011190128],"genre_scores_gemma":[0.0027492838,0.001030447,0.000039980336,0.00033021212,0.00070151093,0.00015158598,0.9906868,0.00010856776,0.004201642],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.997205,0.00008939374,0.0005205625,0.0010131515,0.0004976367,0.00067422196],"domain_scores_gemma":[0.99803454,0.00011210583,0.0003559848,0.00095754635,0.00012414003,0.0004156743],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000059580147,0.00064304465,0.0008872751,0.00015974193,0.00023199682,0.0001805408,0.0003064305,0.00047224568,0.059394024],"category_scores_gemma":[0.000103521204,0.0006418023,0.00022850695,0.00023097078,0.00002519145,0.00019447414,0.00047148834,0.00086443184,0.00089256576],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007084224,0.00009364801,0.000015017584,0.0038766183,0.0001281613,0.0010097963,0.000049092705,0.0000037519276,0.003536422,1.7656849e-7,0.99077684,0.00043962075],"study_design_scores_gemma":[0.0015729973,0.000081179314,0.0007312396,0.007662321,0.0001288512,0.00014784695,0.00006910072,0.00006340052,0.06869794,0.0000012676242,0.92019093,0.000652927],"about_ca_topic_score_codex":0.000018917746,"about_ca_topic_score_gemma":0.000002081404,"teacher_disagreement_score":0.07058592,"about_ca_system_score_codex":0.000112932445,"about_ca_system_score_gemma":0.00013085964,"threshold_uncertainty_score":0.9998854},"labels":[],"label_agreement":null},{"id":"W4394197114","doi":"10.6084/m9.figshare.21947502","title":"Stress granule homeostasis is modulated by TRIM21-mediated ubiquitination of G3BP1 and autophagy-dependent elimination of stress granules","year":2023,"lang":"en","type":"dataset","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Stress granule; Autophagy; Ubiquitin; Cell biology; Chemistry; Granule (geology); Homeostasis; Stress (linguistics); Biology; Biochemistry; Apoptosis","score_opus":0.021567812517655757,"score_gpt":0.2874815996928426,"score_spread":0.2659137871751868,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394197114","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010904508,0.0038181276,3.949313e-7,0.00007007676,0.00008785067,0.0008403443,0.9841771,0.00008815944,0.0000134191105],"genre_scores_gemma":[0.018832816,0.0013699054,0.000004516966,0.000086668515,0.00008084194,0.00017135813,0.9792326,0.00005875347,0.00016253037],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975906,0.00008887946,0.0007014938,0.00050539046,0.00082613644,0.0002875182],"domain_scores_gemma":[0.9977501,0.00025013386,0.00075147947,0.0005643724,0.0005082056,0.00017572877],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009047102,0.00040441038,0.00081803027,0.000477865,0.00006353025,0.000024558682,0.00026077355,0.0005564875,0.015170845],"category_scores_gemma":[0.0006045083,0.00039006778,0.0001802417,0.0004385738,0.000040826017,0.00011787919,0.000118462136,0.00029719347,0.00025708243],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018918992,0.00041284287,0.000009604658,0.004842261,0.00030836806,0.000055895638,0.000098326374,0.0000025636887,0.00041268443,6.374981e-7,0.9905101,0.0031575426],"study_design_scores_gemma":[0.01766857,0.002870197,0.045507226,0.041786574,0.0026447237,0.00003377099,0.0007653107,0.0015093746,0.5570371,0.00017243653,0.327716,0.0022886854],"about_ca_topic_score_codex":0.00025477816,"about_ca_topic_score_gemma":0.000034367033,"teacher_disagreement_score":0.66279405,"about_ca_system_score_codex":0.000064783846,"about_ca_system_score_gemma":0.00016779377,"threshold_uncertainty_score":0.9998551},"labels":[],"label_agreement":null},{"id":"W4394202713","doi":"10.6084/m9.figshare.21077885","title":"Additional file 4 of QKI degradation in macrophage by RNF6 protects mice from MRSA infection via enhancing PI3K p110β dependent autophagy","year":2022,"lang":"en","type":"dataset","venue":"Open MIND","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Autophagy; Degradation (telecommunications); Macrophage; PI3K/AKT/mTOR pathway; Chemistry; Microbiology; Cell biology; Computer science; Biology; Apoptosis; Biochemistry; Telecommunications","score_opus":0.013584315793453075,"score_gpt":0.28022744647264325,"score_spread":0.26664313067919015,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394202713","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0072652213,0.00030128105,0.00001868149,0.000014357491,0.00018112278,0.0016023131,0.990384,0.000004518736,0.00022851868],"genre_scores_gemma":[0.00019541183,0.000106324485,0.0005587117,0.00012580414,0.00014959816,0.001519955,0.9952806,0.000034653993,0.0020288993],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976613,0.00020027607,0.0006260536,0.0006486849,0.00059182616,0.00027185815],"domain_scores_gemma":[0.9982337,0.00046627,0.00057878817,0.00051660935,0.00007015618,0.0001345186],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00019464696,0.0003363103,0.00059871015,0.00024339369,0.000119210075,0.000055044424,0.00036730326,0.00031635215,0.98446476],"category_scores_gemma":[0.00028966798,0.0003557241,0.00012610226,0.0003038848,0.000047095804,0.00022179625,0.00027092994,0.0006872836,0.0006515359],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030795313,0.00062847,0.0000020396883,0.00007306685,0.00015829795,0.00016628832,0.000039381204,0.0000035381827,0.0038801334,5.2847994e-8,0.979692,0.015048807],"study_design_scores_gemma":[0.0013356529,0.00029650077,0.0005547379,0.0005273437,0.00012745912,0.00001849947,0.000030316998,0.00003610701,0.028242258,0.000024821682,0.96851957,0.00028672096],"about_ca_topic_score_codex":0.004325216,"about_ca_topic_score_gemma":0.001561015,"teacher_disagreement_score":0.9838132,"about_ca_system_score_codex":0.0003661929,"about_ca_system_score_gemma":0.0006198154,"threshold_uncertainty_score":0.9998895},"labels":[],"label_agreement":null},{"id":"W4394226398","doi":"10.6084/m9.figshare.13055459","title":"PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vector Institute; University of Toronto; University Health Network; Canadian Institute for Advanced Research","funders":"","keywords":"TFE3; Parkin; Chromosomal translocation; Fusion gene; Cancer research; Papillary renal cell carcinomas; Mitophagy; Biology; Renal cell carcinoma; Medicine; Oncology; Internal medicine; Gene; Genetics; Apoptosis; Gene expression; Autophagy","score_opus":0.02000932659465675,"score_gpt":0.2532565161633074,"score_spread":0.23324718956865065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394226398","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.018636456,0.005115989,4.0403796e-7,0.00013730567,0.0002686761,0.003147184,0.97244585,0.00008928624,0.00015882484],"genre_scores_gemma":[0.05048765,0.00027525402,0.000012088501,0.00022035513,0.0005283921,0.0016764236,0.9462681,0.000087390275,0.00044436252],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99629134,0.00033574188,0.0007839488,0.0010218889,0.0010060992,0.0005609924],"domain_scores_gemma":[0.9980372,0.00021855641,0.00044716714,0.00077264244,0.00018141611,0.0003429817],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022237193,0.00065764465,0.00080282346,0.0004731361,0.00021631316,0.000091689224,0.00036521288,0.00059567584,0.21357132],"category_scores_gemma":[0.000263039,0.00064154476,0.00017742917,0.00044202316,0.000024235229,0.00018494837,0.00016534628,0.001094767,0.0003351666],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051530596,0.0011777219,0.0001746167,0.003125177,0.000058224938,0.00069476303,0.0003175299,0.000009124546,0.0013720123,3.3380007e-7,0.991972,0.0005831874],"study_design_scores_gemma":[0.008890536,0.0014968461,0.014951651,0.00222029,0.00033252756,0.00008736109,0.00017523329,0.00033389346,0.021203095,0.000027023347,0.9489693,0.0013122666],"about_ca_topic_score_codex":0.00015585743,"about_ca_topic_score_gemma":0.00026096497,"teacher_disagreement_score":0.21323615,"about_ca_system_score_codex":0.0002616871,"about_ca_system_score_gemma":0.0009967447,"threshold_uncertainty_score":0.99960357},"labels":[],"label_agreement":null},{"id":"W4394236093","doi":"10.6084/m9.figshare.15022766","title":"CAMK2/CaMKII activates MLKL in short-term starvation to facilitate autophagic flux","year":2021,"lang":"en","type":"dataset","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Health Services","funders":"","keywords":"Term (time); Flux (metallurgy); Autophagy; Starvation; Cell biology; Chemistry; Biology; Physics; Biochemistry; Endocrinology; Apoptosis","score_opus":0.0910774725716745,"score_gpt":0.3238364178400085,"score_spread":0.232758945268334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394236093","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0031278064,0.001053011,1.590267e-7,0.00016578824,0.00014857612,0.00091253436,0.99433863,0.00007599725,0.00017749927],"genre_scores_gemma":[0.00084575143,0.000061440944,0.00001696475,0.001324366,0.00031707634,0.0006409176,0.99553823,0.000045653593,0.0012095774],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978262,0.00007410324,0.00045795337,0.0006876201,0.0004962986,0.00045779467],"domain_scores_gemma":[0.9984021,0.00012597135,0.00007376389,0.00092158176,0.00016646046,0.00031012544],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000058072495,0.0004572533,0.0006779985,0.00033953163,0.00006137403,0.00006485986,0.0002961428,0.0004179849,0.311165],"category_scores_gemma":[0.000633077,0.0004425706,0.00019225702,0.00042752686,0.000008347233,0.00012999939,0.00017734017,0.0005871058,0.0050446806],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000096663534,0.0001861758,0.000020821604,0.0010326317,0.00011276146,0.0011783242,0.00009221508,0.0000062477266,0.00033152406,2.4776176e-7,0.995747,0.0011953374],"study_design_scores_gemma":[0.00059161347,0.000145349,0.010755425,0.004965161,0.000057039953,0.00001799531,0.000039136008,0.0000097513575,0.0025698969,0.00000799929,0.980441,0.00039965403],"about_ca_topic_score_codex":0.000075301774,"about_ca_topic_score_gemma":0.00012611567,"teacher_disagreement_score":0.3061203,"about_ca_system_score_codex":0.00027656675,"about_ca_system_score_gemma":0.00053305796,"threshold_uncertainty_score":0.9998026},"labels":[],"label_agreement":null},{"id":"W4394328934","doi":"10.6084/m9.figshare.16912033","title":"FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma","year":2021,"lang":"en","type":"dataset","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Bruyère; Queen's University","funders":"","keywords":"Glutaminolysis; Autophagy; Exposome; Cancer research; Chemistry; Biology; Medicine; Internal medicine; Pathology; Biochemistry; Glycolysis; Metabolism","score_opus":0.03129880194830402,"score_gpt":0.3038314286885445,"score_spread":0.2725326267402405,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394328934","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003611918,0.036037765,5.6851157e-8,0.00009465007,0.00012779141,0.0005052035,0.9625819,0.00008284135,0.00020861898],"genre_scores_gemma":[0.00066002907,0.00035929977,0.000024472378,0.001254469,0.0005959309,0.0003755535,0.99581784,0.00006418637,0.0008482115],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975987,0.000086699976,0.00050800457,0.0007842327,0.0004984155,0.00052394485],"domain_scores_gemma":[0.99797595,0.00013036584,0.00022355243,0.0013579773,0.00013133716,0.00018079684],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000036353984,0.0005200651,0.00094830996,0.0002248977,0.000069646085,0.00006665711,0.00039293137,0.00072105875,0.44125664],"category_scores_gemma":[0.00048603932,0.0004969883,0.00039738385,0.0005486626,0.000017427488,0.00013659307,0.0002426034,0.0007486101,0.0027489546],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047014164,0.00019952189,0.0000322538,0.0018582271,0.0002733718,0.004800026,0.00005179443,0.0000021749051,0.000012198173,9.895884e-7,0.992502,0.00022044002],"study_design_scores_gemma":[0.0012015725,0.00007070367,0.012672087,0.0072898017,0.00028175558,0.00012389281,0.000041829186,0.00003292992,0.0017889425,0.00003191819,0.9759968,0.00046778301],"about_ca_topic_score_codex":0.00010163978,"about_ca_topic_score_gemma":0.000048231384,"teacher_disagreement_score":0.43850768,"about_ca_system_score_codex":0.00017099088,"about_ca_system_score_gemma":0.00061370846,"threshold_uncertainty_score":0.9997482},"labels":[],"label_agreement":null},{"id":"W4394374452","doi":"10.6084/m9.figshare.16780399.v1","title":"FLT4/VEGFR3 activates AMPK to coordinate glycometabolic reprogramming with autophagy and inflammasome activation for bacterial elimination","year":2021,"lang":"en","type":"dataset","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Reprogramming; Inflammasome; Cell biology; Autophagy; Chemistry; AMPK; Biology; Immunology; Inflammation; Biochemistry; Cell","score_opus":0.02326302588593697,"score_gpt":0.2963894311335139,"score_spread":0.2731264052475769,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394374452","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009937057,0.00028337687,0.000005052292,0.0003002967,0.00010462116,0.0017633189,0.98750305,0.00009290552,0.0000103315615],"genre_scores_gemma":[0.0016853793,0.000038020797,0.00028562205,0.00051816565,0.00088813115,0.0018361469,0.9944874,0.00006784896,0.00019326122],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99823326,0.0000439811,0.0003238888,0.0006999047,0.00032467645,0.00037428938],"domain_scores_gemma":[0.9982425,0.00020277785,0.00030155925,0.0006032674,0.0003940855,0.00025582523],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007064653,0.0004238841,0.0006392345,0.0002894191,0.00015136115,0.00017393766,0.0001514788,0.00036112726,0.015747327],"category_scores_gemma":[0.0011220728,0.00037069008,0.0001227595,0.0003673364,0.000013235748,0.00023382244,0.00010684646,0.00028061672,0.00009361779],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010846977,0.00013330998,0.0000030843123,0.0015492734,0.00029393492,0.00006556769,0.00006233687,0.000001941082,0.0019347311,0.000002215903,0.97862357,0.01624534],"study_design_scores_gemma":[0.0020389329,0.0005141233,0.003307417,0.00374103,0.00021248098,0.000032427804,0.00002834784,0.000013012086,0.028318955,0.000009014492,0.96139354,0.00039071284],"about_ca_topic_score_codex":0.000021835938,"about_ca_topic_score_gemma":0.000010946873,"teacher_disagreement_score":0.026384223,"about_ca_system_score_codex":0.00009914532,"about_ca_system_score_gemma":0.0002612873,"threshold_uncertainty_score":0.99987453},"labels":[],"label_agreement":null},{"id":"W4394379748","doi":"10.6084/m9.figshare.13055459.v2","title":"PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma","year":2021,"lang":"en","type":"dataset","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vector Institute; University of Toronto; University Health Network; Canadian Institute for Advanced Research","funders":"","keywords":"TFE3; Parkin; Chromosomal translocation; Mitophagy; Cancer research; Biology; Cell biology; Medicine; Internal medicine; Apoptosis; Genetics; Autophagy; Gene; Parkinson's disease; Enhancer; Gene expression","score_opus":0.02031789052013558,"score_gpt":0.2549069368395253,"score_spread":0.23458904631938973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394379748","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.021437729,0.008206755,7.731131e-7,0.00014522282,0.00024710924,0.002439393,0.9673024,0.00007248462,0.0001481492],"genre_scores_gemma":[0.055217925,0.00039216303,0.000024708224,0.00021229766,0.0007588101,0.00086898316,0.9420284,0.00008013273,0.0004165685],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964458,0.0002948844,0.00079451624,0.0010529824,0.00085528096,0.00055657735],"domain_scores_gemma":[0.99788964,0.00020972015,0.0004012717,0.00080869504,0.00031672922,0.00037396222],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00017521145,0.00067238027,0.00087746064,0.00037348672,0.00014134376,0.00012416222,0.00028679258,0.00083134044,0.032118175],"category_scores_gemma":[0.00035424693,0.0006421019,0.00018657821,0.00042988508,0.000025094818,0.00018844129,0.00011963894,0.0009113937,0.0004932772],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034230514,0.0012033824,0.00019317775,0.0043678475,0.00006972514,0.0010960052,0.00024862058,0.0000046249866,0.0029564658,2.5380857e-7,0.9888371,0.00068046426],"study_design_scores_gemma":[0.013420821,0.0013858302,0.029297393,0.009781472,0.00056866463,0.00016037798,0.00024093626,0.00054836046,0.10687386,0.000031648036,0.8356293,0.0020613698],"about_ca_topic_score_codex":0.00011381899,"about_ca_topic_score_gemma":0.00038092924,"teacher_disagreement_score":0.15320787,"about_ca_system_score_codex":0.00018482376,"about_ca_system_score_gemma":0.0012159925,"threshold_uncertainty_score":0.99960303},"labels":[],"label_agreement":null},{"id":"W4394424751","doi":"10.6084/m9.figshare.16635159.v1","title":"Autophagy inhibition by TSSC4 (tumor suppressing subtransferable candidate 4) contributes to sustainable cancer cell growth","year":2021,"lang":"en","type":"dataset","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Autophagy; Cancer research; Cancer; Cell biology; Cancer cell; Biology; Chemistry; Apoptosis; Genetics","score_opus":0.009862165818292204,"score_gpt":0.269116043406009,"score_spread":0.2592538775877168,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394424751","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00046537913,0.022918155,0.0000014289352,0.00032939095,0.00015089565,0.0011561994,0.9746206,0.00010216435,0.00025578873],"genre_scores_gemma":[0.0010388206,0.0005770898,0.0000056888366,0.0043375,0.00038097627,0.0013686272,0.98899716,0.00008128574,0.0032128543],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99738663,0.000088275774,0.00043963073,0.0007569329,0.00044577735,0.00088274654],"domain_scores_gemma":[0.9980332,0.000100489706,0.00015523206,0.0006583609,0.00060477847,0.00044790847],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006902175,0.0005440282,0.00083470327,0.00015215375,0.00026890947,0.00022528954,0.00023946282,0.00039296114,0.28293502],"category_scores_gemma":[0.00030355735,0.0005346959,0.00022875144,0.00037320258,0.000014659358,0.0002273891,0.00014445925,0.00055134774,0.0006500986],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016436065,0.00024734501,0.0000032864325,0.004226971,0.00015808077,0.002052034,0.000023441107,0.0000026417738,0.0013796968,0.0000015225237,0.9917057,0.000034890352],"study_design_scores_gemma":[0.0016460514,0.000091812115,0.00004675701,0.0050529954,0.00024353244,0.000017796996,0.00007539369,0.000005402961,0.16598581,0.000017803983,0.8263891,0.0004275609],"about_ca_topic_score_codex":0.0023578424,"about_ca_topic_score_gemma":0.00020025452,"teacher_disagreement_score":0.28228492,"about_ca_system_score_codex":0.0006129577,"about_ca_system_score_gemma":0.001311812,"threshold_uncertainty_score":0.99971044},"labels":[],"label_agreement":null},{"id":"W4394450986","doi":"10.6084/m9.figshare.16635159","title":"Autophagy inhibition by TSSC4 (tumor suppressing subtransferable candidate 4) contributes to sustainable cancer cell growth","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Autophagy; Cancer research; Cancer; Cell biology; Chemistry; Biology; Apoptosis; Genetics; Biochemistry","score_opus":0.009719958283206771,"score_gpt":0.26702353618560587,"score_spread":0.2573035779023991,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394450986","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00039359482,0.013278008,6.72544e-7,0.00031062617,0.00016760487,0.0015716152,0.9838686,0.00013037743,0.00027890346],"genre_scores_gemma":[0.0009214544,0.00037831062,0.000002427286,0.004480829,0.00024598153,0.0029439486,0.9874869,0.00008936617,0.0034507546],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973035,0.000102942664,0.0004326763,0.0007304963,0.00053951994,0.0008909016],"domain_scores_gemma":[0.9983771,0.000105692656,0.00017639119,0.00062343094,0.00031282776,0.0004045578],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009134966,0.00053000334,0.0007515721,0.00020105032,0.000444721,0.00015766596,0.0003183002,0.00026516916,0.8317603],"category_scores_gemma":[0.00021327173,0.00053414237,0.0002155669,0.00038533183,0.000014056269,0.00022248589,0.00021154288,0.0006842576,0.0004102912],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028943983,0.0002619443,0.0000031645116,0.0030943633,0.00013891238,0.0013024772,0.00003410502,0.000006403142,0.00060297037,0.0000022819854,0.9942321,0.000031790518],"study_design_scores_gemma":[0.0019452705,0.00019344453,0.000040448787,0.001692389,0.0002483447,0.000016668213,0.000099719575,0.000005709566,0.05410925,0.000028328299,0.9411382,0.00048220047],"about_ca_topic_score_codex":0.0034281164,"about_ca_topic_score_gemma":0.00012845937,"teacher_disagreement_score":0.83134997,"about_ca_system_score_codex":0.0009221019,"about_ca_system_score_gemma":0.0010366128,"threshold_uncertainty_score":0.99971104},"labels":[],"label_agreement":null},{"id":"W4394495144","doi":"10.6084/m9.figshare.12851429","title":"BNIP3L/NIX degradation leads to mitophagy deficiency in ischemic brains","year":2020,"lang":"en","type":"dataset","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Western University","funders":"","keywords":"Mitophagy; Degradation (telecommunications); Business; Neuroscience; Chemistry; Psychology; Computer science; Autophagy; Telecommunications; Biochemistry","score_opus":0.03949266219458945,"score_gpt":0.31116610369312125,"score_spread":0.2716734414985318,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394495144","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004189696,0.0011749837,3.3593093e-7,0.0003300726,0.00009718469,0.0007166551,0.9966344,0.00007180754,0.00055554777],"genre_scores_gemma":[0.0005387637,0.000037723832,0.00002896644,0.0052239094,0.00046439742,0.00032133478,0.99299705,0.000040995074,0.00034684446],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99829245,0.000034642817,0.000357949,0.00056119263,0.00039547225,0.0003582831],"domain_scores_gemma":[0.9988197,0.000076110366,0.00012919324,0.0005912846,0.0000690057,0.0003146708],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000031797066,0.00034393868,0.00047545947,0.00024562533,0.00004365919,0.000034154415,0.0003616881,0.00035906892,0.105929926],"category_scores_gemma":[0.0007753274,0.0003355184,0.00015854654,0.0005455002,0.0000069049556,0.000076837954,0.00012870212,0.0005442762,0.021203194],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006814292,0.0001257431,0.000011131249,0.000734069,0.000018630784,0.00037511214,0.000033477267,0.0000019265137,0.00023383246,3.6958025e-7,0.99755806,0.00083950185],"study_design_scores_gemma":[0.0006935203,0.00017518677,0.0009035512,0.0024102784,0.000039835,0.000019729105,0.000011643799,0.000007879425,0.0017126097,0.0000032350802,0.9937168,0.0003057339],"about_ca_topic_score_codex":0.000022993498,"about_ca_topic_score_gemma":0.000048556798,"teacher_disagreement_score":0.08472673,"about_ca_system_score_codex":0.00013807425,"about_ca_system_score_gemma":0.00039697348,"threshold_uncertainty_score":0.9999097},"labels":[],"label_agreement":null},{"id":"W4394532851","doi":"10.6084/m9.figshare.13186899.v2","title":"Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3","year":2021,"lang":"en","type":"dataset","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Optineurin; Autophagy; Mesenchymal stem cell; Cell biology; Balance (ability); Biology; Neuroscience; Genetics","score_opus":0.014013133738959191,"score_gpt":0.24758034781170066,"score_spread":0.23356721407274147,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394532851","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.023999836,0.0193756,5.0364267e-8,0.00007776991,0.00018673179,0.0004585465,0.95561886,0.0001706996,0.00011190128],"genre_scores_gemma":[0.0027492838,0.001030447,0.000039980336,0.00033021212,0.00070151093,0.00015158598,0.9906868,0.00010856776,0.004201642],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.997205,0.00008939374,0.0005205625,0.0010131515,0.0004976367,0.00067422196],"domain_scores_gemma":[0.99803454,0.00011210583,0.0003559848,0.00095754635,0.00012414003,0.0004156743],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000059580147,0.00064304465,0.0008872751,0.00015974193,0.00023199682,0.0001805408,0.0003064305,0.00047224568,0.059394024],"category_scores_gemma":[0.000103521204,0.0006418023,0.00022850695,0.00023097078,0.00002519145,0.00019447414,0.00047148834,0.00086443184,0.00089256576],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007084224,0.00009364801,0.000015017584,0.0038766183,0.0001281613,0.0010097963,0.000049092705,0.0000037519276,0.003536422,1.7656849e-7,0.99077684,0.00043962075],"study_design_scores_gemma":[0.0015729973,0.000081179314,0.0007312396,0.007662321,0.0001288512,0.00014784695,0.00006910072,0.00006340052,0.06869794,0.0000012676242,0.92019093,0.000652927],"about_ca_topic_score_codex":0.000018917746,"about_ca_topic_score_gemma":0.000002081404,"teacher_disagreement_score":0.07058592,"about_ca_system_score_codex":0.000112932445,"about_ca_system_score_gemma":0.00013085964,"threshold_uncertainty_score":0.9998854},"labels":[],"label_agreement":null},{"id":"W4394553453","doi":"10.6084/m9.figshare.16750609.v1","title":"Autophagy deficiency activates rDNA transcription","year":2021,"lang":"en","type":"dataset","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Autophagy; Transcription (linguistics); Transcription factor; Cell biology; Chemistry; Biology; Genetics; Gene","score_opus":0.03735224958318312,"score_gpt":0.3004583212097105,"score_spread":0.2631060716265274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394553453","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006062194,0.0073009147,1.6056241e-7,0.00006271188,0.00019401318,0.000358362,0.9914342,0.00010394925,0.0004850309],"genre_scores_gemma":[0.00017353996,0.00022338638,0.00001045969,0.0010479264,0.00049999706,0.00023227051,0.9970119,0.000037450365,0.0007630587],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984964,0.000043522276,0.00026312625,0.0004757258,0.00039748978,0.0003237283],"domain_scores_gemma":[0.99877346,0.000056064153,0.00012955433,0.0007134066,0.00013354525,0.00019396016],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00002489243,0.00033797967,0.0004632058,0.00013128702,0.000089283676,0.00005232683,0.00022071865,0.00045187926,0.5858477],"category_scores_gemma":[0.00032263613,0.00030605844,0.00031673355,0.0002412883,0.000009742432,0.00008778437,0.000046426983,0.00050783705,0.0067024752],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037254344,0.00024422846,2.5054567e-7,0.0012331165,0.000079701786,0.00055801653,0.000013951871,4.6464476e-7,0.00038183836,5.873789e-7,0.99638534,0.0010652324],"study_design_scores_gemma":[0.0005940797,0.00011005828,0.0004248229,0.0034033074,0.00015862618,0.0000742863,0.00001311094,0.0000044766257,0.005898988,0.000013111246,0.98902744,0.00027766862],"about_ca_topic_score_codex":0.000010765547,"about_ca_topic_score_gemma":0.0000041098624,"teacher_disagreement_score":0.5791452,"about_ca_system_score_codex":0.000086409236,"about_ca_system_score_gemma":0.00046552133,"threshold_uncertainty_score":0.99993914},"labels":[],"label_agreement":null},{"id":"W4394561073","doi":"10.6084/m9.figshare.16780399","title":"FLT4/VEGFR3 activates AMPK to coordinate glycometabolic reprogramming with autophagy and inflammasome activation for bacterial elimination","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Inflammasome; Reprogramming; Autophagy; Cell biology; AMPK; Chemistry; Biology; Immunology; Inflammation; Cell; Genetics","score_opus":0.0227551359957866,"score_gpt":0.2934695139608968,"score_spread":0.2707143779651102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394561073","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00839314,0.00016500856,0.0000024371036,0.0002811349,0.0001145005,0.0023396357,0.988577,0.000116015784,0.00001110779],"genre_scores_gemma":[0.0015031457,0.000025406574,0.00012667786,0.0005344022,0.0005848886,0.003812468,0.99313176,0.00007427145,0.00020698467],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99818635,0.000050935854,0.00031899966,0.00067655626,0.00038955983,0.00037759694],"domain_scores_gemma":[0.99843186,0.00021279973,0.0003406501,0.0005726001,0.00020996794,0.00023211686],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000092311966,0.0004134458,0.00057830516,0.00037759557,0.0002447101,0.00012372033,0.00019876323,0.00024807485,0.15209544],"category_scores_gemma":[0.0008011508,0.00037032334,0.00011599494,0.0003787008,0.000012714602,0.00022901155,0.00015377848,0.0003448789,0.000060299582],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017417275,0.00013179927,0.0000027842798,0.0010758644,0.00024319586,0.00003973737,0.00008347878,0.0000042305696,0.00082155387,0.0000030517995,0.9819168,0.013935786],"study_design_scores_gemma":[0.00215791,0.0009447618,0.002600359,0.0011865603,0.00019534887,0.000027484477,0.000033413966,0.000012365848,0.0076876185,0.000012671256,0.98474604,0.00039547076],"about_ca_topic_score_codex":0.00003125516,"about_ca_topic_score_gemma":0.0000071658546,"teacher_disagreement_score":0.15203515,"about_ca_system_score_codex":0.00014642926,"about_ca_system_score_gemma":0.00020863267,"threshold_uncertainty_score":0.9998749},"labels":[],"label_agreement":null},{"id":"W4394684270","doi":"10.1080/15548627.2024.2340399","title":"Mitochondrial import stress and PINK1-mediated mitophagy: the role of the PINK1-TOMM-TIMM23 supercomplex","year":2024,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Structural Genomics Consortium; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Parkinson Canada; Michael J. Fox Foundation for Parkinson's Research","keywords":"PINK1; Mitophagy; Parkin; Biology; Cell biology; Mitochondrion; ATP–ADP translocase; DNAJA3; Translocase; Inner mitochondrial membrane; Ubiquitin ligase; Biochemistry; mitochondrial fusion; Mitochondrial DNA; Ubiquitin; Parkinson's disease; Autophagy; Disease; Medicine","score_opus":0.006430581457789049,"score_gpt":0.2465927709560109,"score_spread":0.24016218949822185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394684270","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9609568,0.032148678,0.000019329778,0.0018481344,0.0014246749,0.0007914496,0.000112936796,0.00019039243,0.0025075718],"genre_scores_gemma":[0.99638206,0.00043675315,0.000054457556,0.0009985113,0.000623597,0.000061777835,0.000047013524,0.00006021871,0.0013356302],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981506,0.00011783514,0.00047362983,0.00043565573,0.00044361613,0.0003786608],"domain_scores_gemma":[0.99863094,0.00027398017,0.000079608544,0.0007996126,0.00007588258,0.00013996396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015935286,0.0002935455,0.0004202825,0.00011546989,0.00018411175,0.00007028718,0.00036546955,0.00017596598,0.00046914697],"category_scores_gemma":[0.00008719786,0.0001621662,0.00029123723,0.0004997535,0.00046285478,0.000113525566,0.00016814264,0.0004226101,0.000069072514],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011163652,0.0015143444,0.063915044,0.0014966149,0.0040992913,0.0007718595,0.006947062,0.000025628487,0.79051125,0.04710419,0.022822427,0.059675895],"study_design_scores_gemma":[0.0039967303,0.00039779354,0.47983384,0.00093016174,0.0008728134,0.00025781937,0.0010772517,0.0057688043,0.34075963,0.012454011,0.15309805,0.0005531126],"about_ca_topic_score_codex":0.00016071032,"about_ca_topic_score_gemma":0.000015105376,"teacher_disagreement_score":0.44975165,"about_ca_system_score_codex":0.000046916215,"about_ca_system_score_gemma":0.00031722683,"threshold_uncertainty_score":0.6612946},"labels":[],"label_agreement":null},{"id":"W4394750027","doi":"10.1007/7651_2024_532","title":"Evaluation of Mitochondrial Phagy (Mitophagy) in Human Non-small Adenocarcinoma Tumor Cells","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"","keywords":"Mitophagy; Autophagy; Mitochondrion; Biology; Lung cancer; Metastasis; Cancer research; Cancer cell; Cancer; Adenocarcinoma; Cell biology; Pathology; Medicine; Apoptosis; Genetics","score_opus":0.04248648374622561,"score_gpt":0.43405353188113777,"score_spread":0.39156704813491217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394750027","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85411286,0.010350834,0.13277328,0.0000556199,0.00083908805,0.0007916927,0.000008021237,0.000028372715,0.0010402211],"genre_scores_gemma":[0.7075274,0.00003629585,0.29160455,0.00028061346,0.00022335578,0.00017200701,0.000041234463,0.00004338353,0.000071160226],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99689895,0.0016180428,0.0005135388,0.0004694978,0.0002129613,0.00028698953],"domain_scores_gemma":[0.9992141,0.00015771356,0.000073354764,0.00038194156,0.00010499557,0.00006786802],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002384465,0.00018894719,0.0004818941,0.0005004431,0.000015378102,0.0000074509817,0.00015407988,0.00020380835,0.00026919844],"category_scores_gemma":[0.00022808088,0.00017133608,0.00016921101,0.00045680188,0.00012037422,0.000021263308,0.00005182022,0.00029822584,0.000011165846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000084339146,0.00015842573,0.0012366014,0.00009187602,0.00009779208,0.00031169728,0.00022698978,0.00004762179,0.9775939,0.0008945272,0.000018778957,0.019237438],"study_design_scores_gemma":[0.0024812901,0.0004146912,0.005199771,0.00014371693,0.00020590259,0.000019552734,0.00004144019,0.0040650764,0.9718877,0.015180539,0.00021391333,0.00014642753],"about_ca_topic_score_codex":0.00009411085,"about_ca_topic_score_gemma":0.000011130243,"teacher_disagreement_score":0.15883128,"about_ca_system_score_codex":0.00013130906,"about_ca_system_score_gemma":0.00029639673,"threshold_uncertainty_score":0.69868827},"labels":[],"label_agreement":null},{"id":"W4394880583","doi":"10.3390/cancers16081520","title":"Identification and In Vivo Validation of Unique Anti-Oncogenic Mechanisms Involving Protein Kinase Signaling and Autophagy Mediated by the Investigational Agent PV-10","year":2024,"lang":"en","type":"article","venue":"Cancers","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Cancer research; Autophagy; Metastasis; Downregulation and upregulation; Medicine; Cancer; Melanoma; Apoptosis; Biology; Internal medicine","score_opus":0.01576360603347984,"score_gpt":0.26866502464831593,"score_spread":0.2529014186148361,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394880583","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99246275,0.005775391,0.00072489935,0.00040372743,0.00006650064,0.00048386565,0.000033564495,0.000032071053,0.000017252976],"genre_scores_gemma":[0.9991168,0.00025250574,0.000087794644,0.00016029201,0.00003114015,0.00009093491,0.000058642174,0.000013571477,0.00018831198],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999269,0.00006200859,0.00022309457,0.0001900857,0.00016390003,0.00009192817],"domain_scores_gemma":[0.9996555,0.00006395316,0.00007058464,0.00010021291,0.000044496708,0.000065256],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031098526,0.000085752705,0.00012048125,0.00008973719,0.00004469993,0.000027812715,0.0000403029,0.00005625198,0.00011167283],"category_scores_gemma":[0.00006834692,0.000068586596,0.000023381179,0.00022690976,0.000099274606,0.00010369586,0.000013988121,0.00008972087,0.0000015127317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027472704,0.000007639483,0.00014723561,0.00016699753,0.000042830972,0.0000089097275,0.00058561866,0.00012453238,0.9970991,0.0012567574,0.00018173737,0.00035118277],"study_design_scores_gemma":[0.00040959317,0.00004096295,0.0010178739,0.0003226298,0.000047894693,0.0000043512314,0.00018650803,0.011361856,0.9826196,0.003771171,0.00014950578,0.00006806942],"about_ca_topic_score_codex":0.00009097088,"about_ca_topic_score_gemma":0.000004749522,"teacher_disagreement_score":0.014479501,"about_ca_system_score_codex":0.00021480411,"about_ca_system_score_gemma":0.0003815152,"threshold_uncertainty_score":0.27968803},"labels":[],"label_agreement":null},{"id":"W4395016393","doi":"10.1007/7651_2024_538","title":"Assessment of Stiffness-Dependent Autophagosome Formation and Apoptosis in Embryonal Rhabdomyosarcoma Tumor Cells","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"","keywords":"Autophagy; Cell biology; Extracellular matrix; Autophagosome; Chemistry; Cancer cell; Tumor microenvironment; Signal transduction; Apoptosis; Programmed cell death; Cancer research; Biology; Cancer; Tumor cells; Biochemistry","score_opus":0.017783269556203317,"score_gpt":0.404833150998748,"score_spread":0.3870498814425447,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395016393","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7136597,0.0027680418,0.28252435,0.0001430393,0.0002061798,0.00029819543,0.000014386433,0.000024859837,0.00036122114],"genre_scores_gemma":[0.74347895,0.00013742055,0.25596586,0.00026923014,0.000021213464,0.00005900361,0.000023661109,0.000015912194,0.000028781129],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984646,0.00053377426,0.00040620417,0.00028366488,0.000105440355,0.00020634149],"domain_scores_gemma":[0.9994751,0.00018912823,0.000058649475,0.00019304402,0.000025465064,0.00005858644],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008750632,0.0001410289,0.00038332274,0.0003784558,0.000012383445,0.000009361763,0.00007747618,0.000115401526,0.00007418322],"category_scores_gemma":[0.000050632214,0.00012048369,0.00007617869,0.00025909426,0.00009332588,0.000045075467,0.00006240678,0.00022879522,0.0000018763767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048540034,0.0001251578,0.001409875,0.00025612934,0.00005112114,0.00014516266,0.000110275,0.000018303612,0.9573105,0.0082460195,0.0000032797961,0.032275654],"study_design_scores_gemma":[0.0014689254,0.00027320476,0.042804725,0.00019417434,0.000059313646,0.000059737802,0.000084518644,0.009427612,0.9321607,0.013008565,0.00030391625,0.00015463746],"about_ca_topic_score_codex":0.000025973843,"about_ca_topic_score_gemma":0.0000017922678,"teacher_disagreement_score":0.04139485,"about_ca_system_score_codex":0.00007646064,"about_ca_system_score_gemma":0.00010732014,"threshold_uncertainty_score":0.49131823},"labels":[],"label_agreement":null},{"id":"W4396229864","doi":"10.1242/dev.202900","title":"Correction: Zebrafish <i>raptor</i> mutation inhibits the activity of mTORC1, inducing craniofacial defects due to autophagy-induced neural crest cell death","year":2024,"lang":"en","type":"erratum","venue":"Development","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Biology; Neural crest; Zebrafish; Autophagy; mTORC1; Craniofacial; Mutation; Cell biology; Programmed cell death; Evolutionary biology; Zoology; Genetics; Gene; Embryo; Apoptosis; Phosphorylation","score_opus":0.019852075441977854,"score_gpt":0.26988370587243005,"score_spread":0.2500316304304522,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396229864","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94347095,0.0005639854,0.000153464,0.00032440005,0.040523563,0.001473693,0.000030443345,0.0002317199,0.013227802],"genre_scores_gemma":[0.9583657,0.000033996315,0.00012754467,0.0011939293,0.002080463,0.00022869708,0.00028330364,0.00013110394,0.03755527],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99705535,0.00012928883,0.0006280043,0.0007659468,0.000927427,0.0004939693],"domain_scores_gemma":[0.99850637,0.000118135074,0.00032305534,0.0005056774,0.00024832378,0.00029846665],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035264087,0.0005991548,0.0008015509,0.00034665567,0.00028618428,0.00008715332,0.00025441908,0.0005634221,0.0001554044],"category_scores_gemma":[0.00012296352,0.00047274175,0.00027361984,0.0006446219,0.00004438214,0.00011230165,0.0001683824,0.001394224,0.00017275596],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008307114,0.0009987893,0.00029370614,0.0019327607,0.001030525,0.0015106434,0.013971979,0.00006738734,0.042347368,0.000052341293,0.8831611,0.05380268],"study_design_scores_gemma":[0.0022539243,0.00082034897,0.15867794,0.0028248485,0.0008086902,0.0003140053,0.0003609253,0.0005457714,0.6526466,0.00008308197,0.17930615,0.0013577173],"about_ca_topic_score_codex":0.00011697552,"about_ca_topic_score_gemma":0.00006735597,"teacher_disagreement_score":0.703855,"about_ca_system_score_codex":0.00053357286,"about_ca_system_score_gemma":0.0024212843,"threshold_uncertainty_score":0.9997724},"labels":[],"label_agreement":null},{"id":"W4396520908","doi":"10.1016/j.abb.2024.110020","title":"The role of labile iron on brain proteostasis; could it be an early event of neurodegenerative disease?","year":2024,"lang":"en","type":"article","venue":"Archives of Biochemistry and Biophysics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Research Council of Thailand; Office of the Higher Education Commission; Chiang Mai University; Providence Health Care","keywords":"Proteostasis; Neurodegeneration; Transferrin receptor; Autophagy; Cell biology; Ferroportin; Chemistry; Lysosome; Biology; Biochemistry; Cell; Disease; Internal medicine; Metabolism; Medicine; Apoptosis","score_opus":0.007517024304109704,"score_gpt":0.26951334620254536,"score_spread":0.26199632189843564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396520908","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957115,0.0017891963,0.000010740384,0.00152043,0.00001704976,0.00020166702,0.0002801851,0.00001060064,0.00045863487],"genre_scores_gemma":[0.99909014,0.0002726242,0.000040484876,0.0001134685,0.00007805411,0.0000143239085,0.000055734305,0.0000107722835,0.00032443143],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993543,0.000029168543,0.00017747818,0.00018687788,0.00015470813,0.00009748041],"domain_scores_gemma":[0.99937093,0.0001720745,0.00007337545,0.00026693425,0.000022043127,0.000094641415],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000039968905,0.000109669134,0.0001565068,0.000015890662,0.00004226051,0.000007676885,0.00008590488,0.000027219148,0.000005182589],"category_scores_gemma":[0.000026049926,0.000072782525,0.00010344856,0.00006891669,0.00030544458,0.000025819732,0.000030937375,0.000095766205,3.1278586e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00074830005,0.00033332384,0.00029292094,0.00042770422,0.00008317403,0.0000053206063,0.00055393646,0.0000044846956,0.9751949,0.0015125757,0.00005683146,0.02078658],"study_design_scores_gemma":[0.0002509885,0.00059815333,0.003736674,0.00025333877,0.00006491625,7.125098e-7,0.00020115662,0.0004932533,0.9906123,0.0033442953,0.00037727377,0.00006690328],"about_ca_topic_score_codex":0.000010348526,"about_ca_topic_score_gemma":2.4406373e-7,"teacher_disagreement_score":0.020719675,"about_ca_system_score_codex":0.0000037513937,"about_ca_system_score_gemma":0.000094568,"threshold_uncertainty_score":0.29679853},"labels":[],"label_agreement":null},{"id":"W4396802911","doi":"10.1080/15548627.2024.2353443","title":"Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR","year":2024,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Defense Threat Reduction Agency","keywords":"ATG8; Biology; Autophagy; Acetylation; Cell biology; Receptor; Characterization (materials science); Genetics; Gene; Apoptosis; Nanotechnology","score_opus":0.012053051358425916,"score_gpt":0.24278961978235603,"score_spread":0.23073656842393012,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396802911","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99538964,0.00036991367,0.00004733549,0.0022255098,0.00032105096,0.00090658024,0.000064780135,0.00003056417,0.00064464385],"genre_scores_gemma":[0.99804354,0.000016524704,0.000014794997,0.0003176795,0.00016977594,0.0000675081,0.000029969551,0.0000232947,0.0013169175],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988676,0.00013948488,0.00029353375,0.0001912874,0.00038574322,0.00012238172],"domain_scores_gemma":[0.9989921,0.000137786,0.00024852014,0.0004608051,0.00013228606,0.000028491138],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015968722,0.00015461489,0.00019311714,0.00005349677,0.00024102145,0.000022052682,0.0001668899,0.00005987101,0.0003626234],"category_scores_gemma":[0.00002761944,0.00006098315,0.00013864326,0.00034161756,0.00035484423,0.00012045078,0.000057797442,0.00026449678,0.0000037008924],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018191538,0.000072422554,0.0013604768,0.00007276273,0.00024071582,5.3177405e-7,0.0013553047,0.000024684452,0.9641031,0.028347924,0.000121412224,0.0041187443],"study_design_scores_gemma":[0.0003813818,0.00018977188,0.56238955,0.00026504698,0.000135062,0.000011614964,0.0002729925,0.000955975,0.4317115,0.0007541443,0.0028714698,0.00006145403],"about_ca_topic_score_codex":0.000049475686,"about_ca_topic_score_gemma":0.000009934964,"teacher_disagreement_score":0.5610291,"about_ca_system_score_codex":0.000039783165,"about_ca_system_score_gemma":0.00014238509,"threshold_uncertainty_score":0.3970472},"labels":[],"label_agreement":null},{"id":"W4397045393","doi":"10.1681/asn.20233411s1119b","title":"Autophagy Inhibition Aggravates Renal Microvascular Injury Secondary to Ischemia-Reperfusion","year":2023,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Autophagy; Medicine; Ischemia; Reperfusion injury; Renal injury; Cardiology; Internal medicine; Kidney; Pharmacology; Biology; Apoptosis; Biochemistry","score_opus":0.0095733691462842,"score_gpt":0.27901811478387256,"score_spread":0.26944474563758836,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4397045393","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98661184,0.00041172266,0.00008625935,0.012549494,0.00011437707,0.00014457396,0.000008759147,0.000025770709,0.000047173486],"genre_scores_gemma":[0.9730354,0.0009813242,0.0018399362,0.02338068,0.00047637132,0.0000039189526,0.000005910607,0.000024747804,0.0002517357],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986993,0.000097787415,0.00047058222,0.00014896854,0.00033588603,0.00024746291],"domain_scores_gemma":[0.99859357,0.000078097306,0.00067831314,0.00030653403,0.00020283711,0.00014063633],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000461599,0.00014077972,0.00054581405,0.00010305755,0.00009018057,0.000005541631,0.00019267415,0.00008061655,0.0001016834],"category_scores_gemma":[0.000044884797,0.00009610733,0.00086410233,0.00067650893,0.00043420735,0.000058404574,0.00012522106,0.0003972795,0.000020178572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004896456,0.00007762937,0.0002699603,0.00002448963,0.00037837366,0.000022090473,0.00053790864,0.000028744536,0.8288133,0.000005015167,0.1627216,0.0066312426],"study_design_scores_gemma":[0.001448035,0.00165043,0.05354024,0.00013303448,0.00023559442,0.00037625042,0.0006864849,0.00009159159,0.89205474,0.00046097764,0.04920005,0.00012255303],"about_ca_topic_score_codex":0.000027969294,"about_ca_topic_score_gemma":5.851023e-7,"teacher_disagreement_score":0.113521546,"about_ca_system_score_codex":0.00006417193,"about_ca_system_score_gemma":0.00024555848,"threshold_uncertainty_score":0.39191434},"labels":[],"label_agreement":null},{"id":"W4398165821","doi":"10.1152/physiol.2024.39.s1.1297","title":"Intersection of chronic contractile activity and lysosomal defects in mediating lysosomal adaptations in skeletal muscle cells","year":2024,"lang":"en","type":"article","venue":"Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Cell biology; Biology; Skeletal muscle; Anatomy; Intersection (aeronautics); Internal medicine; Endocrinology; Chemistry; Medicine","score_opus":0.011243584903986381,"score_gpt":0.2781893767611204,"score_spread":0.266945791857134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4398165821","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99822783,0.0010376235,0.00003832702,0.000057531593,0.00023709894,0.00017438304,0.0000062176214,0.000025930436,0.00019502666],"genre_scores_gemma":[0.99964,0.00011481083,0.000016407781,0.0000313037,0.00013562043,0.00002803969,0.000011991572,0.000010463787,0.0000113478745],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9993822,0.00006853373,0.00014998218,0.00019232312,0.000054667264,0.0001523131],"domain_scores_gemma":[0.9996208,0.00020542373,0.000040542862,0.00008336619,0.000013106898,0.00003676199],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006332697,0.00008271903,0.00022309397,0.00014428029,0.000015080743,0.0000032084085,0.000024929917,0.00007260438,0.000064285276],"category_scores_gemma":[0.000030671046,0.00007662403,0.000050818657,0.00015785586,0.00007158882,0.0000985642,0.000018551114,0.0001907388,0.0000072038697],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006829631,0.00017813031,0.0005735695,0.0001338003,0.000031708587,0.00003103357,0.0005401462,0.00009380322,0.98432577,0.00022876942,0.000005515692,0.013789452],"study_design_scores_gemma":[0.0011461905,0.00039585834,0.876634,0.00013592684,0.000033876942,0.0000075878493,0.0001832838,0.020550486,0.10005426,0.00072343525,0.000054127777,0.000080972524],"about_ca_topic_score_codex":0.00019227558,"about_ca_topic_score_gemma":0.00024692976,"teacher_disagreement_score":0.8842715,"about_ca_system_score_codex":0.00008642362,"about_ca_system_score_gemma":0.00011213587,"threshold_uncertainty_score":0.3124637},"labels":[],"label_agreement":null},{"id":"W4398182681","doi":"10.1007/s00421-024-05503-5","title":"The biphasic activity of autophagy and heat shock protein response in peripheral blood mononuclear cells following acute resistance exercise in resistance-trained males","year":2024,"lang":"en","type":"article","venue":"European Journal of Applied Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Peripheral blood mononuclear cell; Sports medicine; Resistance training; Peripheral resistance; Medicine; Shock (circulatory); Human physiology; Peripheral; Autophagy; Peripheral blood; Heat shock protein; Internal medicine; Cardiology; Immunology; Blood pressure; Pathology; Biology; Heart rate; In vitro; Biochemistry","score_opus":0.007611643397199621,"score_gpt":0.24231880791837673,"score_spread":0.23470716452117713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4398182681","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99323195,0.005228563,0.000013687716,0.00034912545,0.00009493962,0.00037061225,0.000006271173,0.000017412613,0.00068746175],"genre_scores_gemma":[0.99819285,0.000693469,0.00043693435,0.00005028164,0.000082718885,0.00000871848,8.526151e-7,0.000047573165,0.00048661622],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982648,0.00047154294,0.0005393571,0.00026293582,0.00018167464,0.0002797247],"domain_scores_gemma":[0.99926865,0.00019512585,0.00014784142,0.0002597791,0.0000303723,0.00009822343],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011043387,0.0001967441,0.00052787975,0.00017870238,0.00006768181,0.000024298804,0.00019415001,0.00004931232,0.000016803011],"category_scores_gemma":[0.000024075061,0.00013977014,0.00016237603,0.00028263876,0.00019414266,0.000081752216,0.000049088772,0.00046535724,0.0000035263004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.056899283,0.00012896348,0.0000072494563,0.00013252487,0.00019844653,0.0018565804,0.001561473,0.000036708512,0.93758273,0.00021835405,0.00007274781,0.0013049621],"study_design_scores_gemma":[0.01513403,0.0017695106,0.28950047,0.004613731,0.0005520149,0.00007931286,0.0012971476,0.00030816474,0.67954284,0.0037276333,0.0028740286,0.0006010866],"about_ca_topic_score_codex":0.0000016524245,"about_ca_topic_score_gemma":0.0000036092576,"teacher_disagreement_score":0.28949323,"about_ca_system_score_codex":0.00005294977,"about_ca_system_score_gemma":0.00014532087,"threshold_uncertainty_score":0.5699661},"labels":[],"label_agreement":null},{"id":"W4398194335","doi":"10.1139/cjpp-2023-0432","title":"Chloramphenicol alleviates 5-fluorouracil-induced cellular senescence through activation of autophagy","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Senescence; Autophagy; Biology; Cell biology; Downregulation and upregulation; Cancer research; PI3K/AKT/mTOR pathway; Signal transduction; Biochemistry; Apoptosis; Gene","score_opus":0.022918399192476634,"score_gpt":0.3031071334573603,"score_spread":0.28018873426488367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4398194335","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924993,0.0049774535,0.00014658965,0.0011844038,0.0008740742,0.00014792394,0.000010050649,0.000009528309,0.00015067427],"genre_scores_gemma":[0.9977917,0.0003799325,0.00007832227,0.0011570458,0.00050050806,0.0000041294898,0.000008338683,0.0000135050295,0.00006650462],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99914473,0.00009859534,0.0003130073,0.0001487454,0.00006475975,0.00023016473],"domain_scores_gemma":[0.9992417,0.00012863537,0.00013774335,0.00007762285,0.00013513824,0.00027915902],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014315432,0.00012726474,0.00035044277,0.00016094703,0.00006951801,0.000006477407,0.00009167883,0.00015283388,0.0018000529],"category_scores_gemma":[0.0000196922,0.000105620835,0.000113225215,0.00014821175,0.00018436041,0.0001537446,0.000008495511,0.00032031484,0.000008425093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020159392,0.000037223796,0.00017784846,0.00023303177,0.00038920983,0.00027964037,0.000771289,0.000012105311,0.99414617,0.00068519666,0.001229095,0.0018375822],"study_design_scores_gemma":[0.00088671787,0.00058944325,0.0041451934,0.000102154576,0.00022201061,0.00016866322,0.00006540356,0.00024495923,0.98498476,0.0031903281,0.005311208,0.00008915412],"about_ca_topic_score_codex":0.00026404264,"about_ca_topic_score_gemma":0.000020661999,"teacher_disagreement_score":0.009161419,"about_ca_system_score_codex":0.00005463085,"about_ca_system_score_gemma":0.0011134928,"threshold_uncertainty_score":0.9991124},"labels":[],"label_agreement":null},{"id":"W4398204326","doi":"10.3390/ijms25115633","title":"Valosin-Containing Protein (VCP): A Review of Its Diverse Molecular Functions and Clinical Phenotypes","year":2024,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Heritage Medical Research Clinic; Université Laval; University of Calgary","funders":"","keywords":"AAA proteins; Biology; Cell biology; Endoplasmic-reticulum-associated protein degradation; Endoplasmic reticulum; Phenotype; DNA repair; DNA damage; Proteostasis; Unfolded protein response; ATPase; Genetics; DNA; Biochemistry; Gene; Enzyme","score_opus":0.06918018669104681,"score_gpt":0.43708309034958476,"score_spread":0.36790290365853795,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4398204326","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012911087,0.995992,0.00024330677,0.0003901875,0.00071944314,0.00041573695,0.000024458539,0.000008420742,0.00091530837],"genre_scores_gemma":[0.0021302023,0.9965171,0.0005266086,0.00045739557,0.00022798934,0.000008939088,0.000008063349,0.000018004499,0.00010570044],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971832,0.00019605133,0.0011659244,0.0002759654,0.0010458685,0.00013298249],"domain_scores_gemma":[0.998124,0.000083796636,0.0009253878,0.00013704067,0.0005762183,0.00015356469],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012849296,0.00022187208,0.0010837137,0.00039176323,0.000036199508,0.00005174993,0.00047950147,0.00011081302,0.000088757144],"category_scores_gemma":[0.00046387553,0.00014593078,0.00097219995,0.00032180853,0.00027966028,0.000120384066,0.00013039022,0.00043051256,0.000020229536],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000702891,0.00025560308,0.000014007476,0.022651637,0.0035100472,0.0024224506,0.00003833012,0.0000011682312,0.00017685129,0.0027350206,0.0004751504,0.96764946],"study_design_scores_gemma":[0.0008625403,0.0016479942,0.000018538436,0.45322073,0.008208394,0.002167681,0.00008379388,0.000030342866,0.00022399177,0.0007470246,0.53244096,0.00034802879],"about_ca_topic_score_codex":0.0000025331738,"about_ca_topic_score_gemma":2.1677563e-7,"teacher_disagreement_score":0.9673014,"about_ca_system_score_codex":0.000056899527,"about_ca_system_score_gemma":0.0011102359,"threshold_uncertainty_score":0.5950884},"labels":[],"label_agreement":null},{"id":"W4399206083","doi":"10.1016/j.coisb.2024.100519","title":"ODE-based models of signaling networks in autophagy","year":2024,"lang":"en","type":"article","venue":"Current Opinion in Systems Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Deutsche Forschungsgemeinschaft; Austrian Science Fund; European Commission; HORIZON EUROPE Framework Programme; Ministère de l'Économie, de la Science et de l'Innovation - Québec","keywords":"Ode; Autophagy; Computer science; Biology; Mathematics; Genetics; Applied mathematics","score_opus":0.0794962287273232,"score_gpt":0.37805388525299505,"score_spread":0.29855765652567184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399206083","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5218501,0.39389133,0.060949445,0.00015513983,0.021275556,0.0013008832,0.000052968364,0.00018694406,0.0003376225],"genre_scores_gemma":[0.99829024,0.00090056006,0.000025961212,0.000017425635,0.0005079236,0.00009550414,0.00013274408,0.000017661387,0.000011957178],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99860376,0.00017158384,0.0005789382,0.0003034659,0.0000909835,0.00025125436],"domain_scores_gemma":[0.99947196,0.00014901912,0.000074318246,0.00020337239,0.000036990074,0.00006433071],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037645394,0.00014601539,0.00043269884,0.00035438308,0.0000114403065,0.000008654524,0.00009135104,0.00017668476,0.000029869534],"category_scores_gemma":[0.00001454358,0.000120396115,0.00009806131,0.00036800953,0.00006637379,0.00004397291,0.000019494952,0.00025242363,0.000008606962],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001989401,0.0029086638,0.118352845,0.02423511,0.0005464246,0.00014132397,0.0027055403,0.44790435,0.015190382,0.23898603,0.00406367,0.14297625],"study_design_scores_gemma":[0.0019122224,0.0002526986,0.0027394188,0.0059830947,0.000016231155,0.0000123388045,0.00007007227,0.98019,0.0005257909,0.0014306539,0.006676771,0.00019070168],"about_ca_topic_score_codex":0.000071489885,"about_ca_topic_score_gemma":8.6683184e-7,"teacher_disagreement_score":0.53228563,"about_ca_system_score_codex":0.000085371095,"about_ca_system_score_gemma":0.00017470766,"threshold_uncertainty_score":0.4909611},"labels":[],"label_agreement":null},{"id":"W4399213047","doi":"10.1101/2024.05.31.596776","title":"PEX14 functions as a molecular link between optineurin and pexophagy in human cells","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; KU Leuven; University of Toronto; University of Illinois at Urbana-Champaign; Universiteit van Amsterdam","keywords":"Optineurin; Interface (matter); Cell biology; Cell; Chemistry; Biology; Autophagy; Genetics; Biochemistry","score_opus":0.01227383277180413,"score_gpt":0.2550176398274708,"score_spread":0.24274380705566664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399213047","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898469,0.007097525,0.000098644385,0.00062028645,0.00055528345,0.0010008218,0.00018105832,0.0004951603,0.00010434285],"genre_scores_gemma":[0.9971834,0.00032561715,0.0004530609,0.00035779434,0.0011535888,0.00023111461,0.0000016001849,0.00020929443,0.00008454523],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971823,0.00010478251,0.00060891284,0.0011794241,0.00039378926,0.00053075276],"domain_scores_gemma":[0.99796313,0.00004980393,0.00017914061,0.001152269,0.00017712142,0.0004785075],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034825722,0.0006143474,0.0008149695,0.0006008494,0.000105450694,0.00015712918,0.0002499365,0.0006348026,0.00013526526],"category_scores_gemma":[0.00006023049,0.00065019657,0.00023371427,0.0005198952,0.00014759968,0.00005502121,0.0005667891,0.0015539945,0.00018832948],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060048278,0.00017552679,0.004829504,0.0015036454,0.0005482343,0.0021740787,0.000025691576,0.000026167234,0.98952854,0.00077744736,0.0003386004,0.000012501557],"study_design_scores_gemma":[0.0019697242,0.00031179175,0.1317992,0.001543704,0.001105477,1.728396e-7,0.0000069595444,0.00013194534,0.85683113,0.00008451088,0.0051757395,0.0010396015],"about_ca_topic_score_codex":0.00008413173,"about_ca_topic_score_gemma":8.95573e-7,"teacher_disagreement_score":0.13269739,"about_ca_system_score_codex":0.0001983371,"about_ca_system_score_gemma":0.0006112557,"threshold_uncertainty_score":0.9995949},"labels":[],"label_agreement":null},{"id":"W4399295277","doi":"10.1016/j.bbrc.2024.150198","title":"Downregulation of O-GlcNAc transferase activity impairs basal autophagy and late endosome positioning under nutrient-rich conditions in human colon cells","year":2024,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Région Hauts-de-France; Simon Fraser University; Ligue Contre le Cancer; Université de Lille","keywords":"Autophagy; Cell biology; Endosome; Autophagosome; Lysosome; Downregulation and upregulation; Vacuole; Biology; ATG16L1; mTORC1; Nutrient sensing; Flux (metallurgy); Gene silencing; Chemistry; Cytoplasm; Intracellular; Biochemistry; Signal transduction; Enzyme; Gene; Apoptosis","score_opus":0.04609107002883561,"score_gpt":0.3951298880993953,"score_spread":0.3490388180705597,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399295277","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949703,0.001216877,0.000057347333,0.002945264,0.0000095973755,0.00041058983,0.00010460934,0.000040919516,0.0002444545],"genre_scores_gemma":[0.9986858,0.0007552854,0.0001284307,0.00004380844,0.00003921448,0.00008082017,0.00017077361,0.000012650038,0.000083242754],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988378,0.00018688767,0.0002105881,0.0002557782,0.00027783005,0.00023106024],"domain_scores_gemma":[0.9987095,0.0005610829,0.000019901287,0.0004146834,0.00010986254,0.00018494908],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025140806,0.00011087863,0.00021093094,0.00020858717,0.00022167565,0.00004276019,0.00013817009,0.00011299655,0.000037135018],"category_scores_gemma":[0.00003202897,0.00009675569,0.00006748439,0.00057084695,0.0008437457,0.000114198025,0.000110133326,0.00047770748,0.000004913242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000106108586,0.0007716728,0.000068450565,0.00014516087,0.000048470447,0.0000062684453,0.00020093599,8.9619886e-7,0.97984254,0.01827759,0.00007622887,0.00045567504],"study_design_scores_gemma":[0.0009683782,0.00032423623,0.06460184,0.0003138969,0.000052938954,0.000004144484,0.00008519121,0.004413046,0.9144907,0.014566958,0.00006388352,0.00011481229],"about_ca_topic_score_codex":0.000100457,"about_ca_topic_score_gemma":0.0000053070357,"teacher_disagreement_score":0.06535187,"about_ca_system_score_codex":0.00007630606,"about_ca_system_score_gemma":0.00010365988,"threshold_uncertainty_score":0.39455825},"labels":[],"label_agreement":null},{"id":"W4399303885","doi":"10.3390/cells13110958","title":"Exploring Importance and Regulation of Autophagy in Cancer Stem Cells and Stem Cell-Based Therapies","year":2024,"lang":"en","type":"review","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences; Kyung Hee University","keywords":"Autophagy; Cancer stem cell; Stem cell; Cell biology; Biology; Context (archaeology); Regeneration (biology); Cancer cell; Cancer; Cancer research; Apoptosis; Genetics","score_opus":0.11421560545528926,"score_gpt":0.333289681095594,"score_spread":0.21907407564030473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399303885","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.035986166,0.9626566,0.000005142906,0.000014504826,0.00031676522,0.0008103207,0.000059846097,0.000040313233,0.00011030579],"genre_scores_gemma":[0.015234404,0.9828525,0.000037280945,0.00003763475,0.000112995105,0.00018805818,0.00001370477,0.00007378264,0.0014496361],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984969,0.000073829775,0.00058505137,0.00044626786,0.000191827,0.00020612979],"domain_scores_gemma":[0.9991728,0.00009384138,0.00026984923,0.00032939346,0.00003025908,0.0001038352],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017663192,0.0003548292,0.0012528906,0.0002471331,0.00002355763,0.000021445663,0.000074113,0.00017625617,0.000059485486],"category_scores_gemma":[5.0400786e-7,0.00026975077,0.00017475717,0.00026309083,0.00009827772,0.00007754388,0.000030230245,0.00024881194,0.000008695955],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050325216,0.00011148537,0.00006691745,0.08810614,0.0002441823,0.000115702074,0.0007832494,0.000009458737,0.001763934,0.00006635616,0.0001900263,0.9084922],"study_design_scores_gemma":[0.0024034607,0.00035567183,0.0005255747,0.07134694,0.0037247792,0.000015832027,0.00036872653,0.00033380973,0.07750307,0.000105966785,0.84228396,0.0010322212],"about_ca_topic_score_codex":0.000021669257,"about_ca_topic_score_gemma":0.0000041800445,"teacher_disagreement_score":0.90746,"about_ca_system_score_codex":0.00008805643,"about_ca_system_score_gemma":0.00030230274,"threshold_uncertainty_score":0.99997544},"labels":[],"label_agreement":null},{"id":"W4399391820","doi":"10.1172/jci177142","title":"Off-target autophagy inhibition by SHP2 allosteric inhibitors contributes to their antitumor activity in RAS-driven cancers","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"National Cancer Institute; National Institutes of Health","keywords":"Allosteric regulation; Autophagy; MAPK/ERK pathway; Cancer research; Kinase; Signal transduction; Cancer; Biology; Enzyme; Cell biology; Biochemistry; Genetics","score_opus":0.040283755030534614,"score_gpt":0.36921816522349443,"score_spread":0.3289344101929598,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399391820","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.986037,0.002310992,0.0006418532,0.009274102,0.0012480516,0.00034621824,0.000024010698,0.000037853217,0.000079914535],"genre_scores_gemma":[0.99492633,0.00047255424,0.00039334933,0.0032888781,0.00074636075,0.000010641591,0.000023592964,0.00002391058,0.00011436344],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977287,0.0002635685,0.0012213272,0.00024329095,0.0003337033,0.00020940148],"domain_scores_gemma":[0.9984721,0.00044658154,0.0003873935,0.0001398484,0.00018116273,0.00037289798],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013565056,0.00017134378,0.0006333426,0.0002682376,0.000036998586,0.000056991536,0.000080510996,0.00018728532,0.00004980449],"category_scores_gemma":[0.00075105875,0.000131309,0.0002782066,0.00049068365,0.0001529586,0.00040891144,0.000026402871,0.00062325835,0.000017458362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003888759,0.0012397266,0.12425887,0.00054569024,0.0010922021,0.0012034732,0.0012881455,0.0008842827,0.67646927,0.001028185,0.09476052,0.09334086],"study_design_scores_gemma":[0.008035557,0.003198212,0.34293562,0.004805043,0.00032682496,0.00010668801,0.00015654096,0.013752751,0.57552296,0.012039048,0.038656197,0.00046455688],"about_ca_topic_score_codex":0.000026161119,"about_ca_topic_score_gemma":0.000012619693,"teacher_disagreement_score":0.21867676,"about_ca_system_score_codex":0.0002775994,"about_ca_system_score_gemma":0.00083383365,"threshold_uncertainty_score":0.53546256},"labels":[],"label_agreement":null},{"id":"W4399504642","doi":"10.1158/1538-8514.synthleth24-a011","title":"Abstract A011: Enhancing chaperone-mediated autophagy to impede glioblastoma growth","year":2024,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Autophagy; Downregulation and upregulation; Cancer research; Cell growth; Cell; Cell biology; Cancer cell; Gene knockdown; Cell cycle; Lysosome; Glioblastoma; Cell culture; Biology; Cancer; Apoptosis; Biochemistry; Gene; Genetics","score_opus":0.014623750132437874,"score_gpt":0.30705426175059897,"score_spread":0.2924305116181611,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399504642","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95741504,0.032216717,0.0039296914,0.0032159507,0.00080051494,0.00063050067,0.000057241654,0.00057468686,0.0011596697],"genre_scores_gemma":[0.9843173,0.0010297511,0.0002376044,0.013279263,0.00037275447,0.00014655244,0.000024520814,0.00014013203,0.0004521364],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980098,0.000033205575,0.0003609618,0.00054260885,0.00049012585,0.00056330307],"domain_scores_gemma":[0.998987,0.000060804843,0.00004788278,0.00043105293,0.00012082267,0.00035242256],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001463531,0.0003542171,0.0003669614,0.00024605784,0.00008508047,0.00009076548,0.00019115223,0.00017670145,0.000815258],"category_scores_gemma":[0.000016793792,0.00031360524,0.00024412764,0.0006026054,0.00006246972,0.00009474997,0.00004784984,0.00035103504,0.00044007174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003466074,0.0001260025,0.000091159745,0.00025033852,0.0008596836,0.001224718,0.0011094647,0.000025922407,0.9709714,0.0008872622,0.00027219133,0.02383527],"study_design_scores_gemma":[0.0009892759,0.00049693626,0.004638691,0.00049284456,0.00038581813,0.00005166907,0.000097147604,0.0009814102,0.95834845,0.00051902153,0.032535408,0.00046335175],"about_ca_topic_score_codex":0.00007413147,"about_ca_topic_score_gemma":0.000022807988,"teacher_disagreement_score":0.032263216,"about_ca_system_score_codex":0.0002492017,"about_ca_system_score_gemma":0.00042215994,"threshold_uncertainty_score":0.9999316},"labels":[],"label_agreement":null},{"id":"W4399591669","doi":"10.1016/j.bbadis.2024.167289","title":"Autophagy unveiled: New horizons in health and disease","year":2024,"lang":"en","type":"editorial","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"","keywords":"Autophagy; New horizons; Disease; Biology; Medicine; Engineering; Pathology; Genetics; Apoptosis","score_opus":0.007580714529842358,"score_gpt":0.29119886298050984,"score_spread":0.28361814845066746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399591669","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.79303044,0.046641823,0.000049672308,0.020801296,0.12933046,0.0032806925,0.006136492,0.0004946799,0.00023443866],"genre_scores_gemma":[0.8237431,0.01170729,0.00043084903,0.0036519805,0.1508329,0.00028028115,0.007184169,0.0006676983,0.0015016968],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9943472,0.0003455634,0.0011816958,0.0017152837,0.0015476419,0.00086261315],"domain_scores_gemma":[0.99302024,0.00025970172,0.0005640021,0.0016679057,0.00017257266,0.0043155877],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002685824,0.0011152648,0.0016817072,0.00077504636,0.000088598776,0.00012842265,0.00055126956,0.0005356939,0.00007769631],"category_scores_gemma":[0.0009951938,0.0010739188,0.0010240503,0.0007994396,0.00038062214,0.00015139008,0.00036963576,0.0011501603,0.000050094302],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0055406424,0.0025306297,0.000010882879,0.007674508,0.001402969,0.0014572437,0.0003549419,0.0000036307306,0.028265016,0.0009883721,0.950266,0.0015051528],"study_design_scores_gemma":[0.042946197,0.010973437,0.019522507,0.045764424,0.020012205,0.000019346642,0.00049989426,0.0012286581,0.22320352,0.045214444,0.5784864,0.012128975],"about_ca_topic_score_codex":0.00020771482,"about_ca_topic_score_gemma":0.000004564984,"teacher_disagreement_score":0.37177962,"about_ca_system_score_codex":0.0002601836,"about_ca_system_score_gemma":0.011122096,"threshold_uncertainty_score":0.9991711},"labels":[],"label_agreement":null},{"id":"W4399604216","doi":"10.1101/2024.06.12.24308722","title":"Mutations in EPG5 are associated with a wide spectrum of neurodevelopmental and neurodegenerative disorders","year":2024,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Children's Hospital of Eastern Ontario; University of British Columbia; University Health Network","funders":"ZonMw","keywords":"Neuroscience; Genetics; Medicine; Biology","score_opus":0.012145621167150962,"score_gpt":0.25561394606489846,"score_spread":0.2434683248977475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399604216","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957847,0.0009490526,0.000022962144,0.0018569021,0.0001440104,0.0005341408,0.00008057679,0.00005694333,0.0005707047],"genre_scores_gemma":[0.9988994,0.00024184263,0.000053162003,0.00022717264,0.000023949797,0.00007181433,0.00010902611,0.000045932306,0.00032772037],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9988104,0.00007664373,0.00028050563,0.0004323986,0.00022409939,0.00017594252],"domain_scores_gemma":[0.99943674,0.0000885281,0.00015238015,0.0002052571,0.00003262187,0.00008445819],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010225544,0.0002357575,0.00042807643,0.00022481415,0.000028156184,0.000016267139,0.00007403105,0.000108585176,0.000038940954],"category_scores_gemma":[0.00011276906,0.0001924502,0.00006605833,0.00025821204,0.00013990195,0.000020772048,0.00015519581,0.0005448807,0.0000037983448],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017082632,0.00036113837,0.99506515,0.00033944368,0.0004220638,0.000482122,0.0018546525,0.00032623103,0.00049500243,0.0001189096,0.00010403842,0.0002604118],"study_design_scores_gemma":[0.0009126387,0.00013116398,0.9906836,0.00080656895,0.00016575502,0.000007307438,0.00017402651,0.0006791387,0.0026306435,0.0036093798,0.000025490477,0.00017424907],"about_ca_topic_score_codex":0.000059525206,"about_ca_topic_score_gemma":0.00070894754,"teacher_disagreement_score":0.004381522,"about_ca_system_score_codex":0.00005631773,"about_ca_system_score_gemma":0.000228056,"threshold_uncertainty_score":0.78478914},"labels":[],"label_agreement":null},{"id":"W4399660834","doi":"10.1016/j.cstres.2024.06.001","title":"Mild heat shock at 40 °C increases levels of autophagy: Role of Nrf2","year":2024,"lang":"en","type":"article","venue":"Cell Stress and Chaperones","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Université du Québec à Montréal","keywords":"Autophagy; ATG5; Cell biology; Heat shock; Heat shock protein; HSF1; Cellular stress response; ATG12; Vacuole; Apoptosis; Downregulation and upregulation; Biology; Chemistry; Hsp70; Cytoplasm; Biochemistry; Fight-or-flight response; Gene","score_opus":0.01367121347451343,"score_gpt":0.25474783812174184,"score_spread":0.2410766246472284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399660834","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.913225,0.08450192,0.0000041287262,0.000073925425,0.000063963635,0.000121201134,0.00020211034,0.00003783875,0.0017699341],"genre_scores_gemma":[0.996111,0.0023041903,0.000030864125,0.000079568425,0.00010056775,0.000009087579,0.000024954941,0.000020682903,0.001319092],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992594,0.00001655113,0.00020966167,0.00020411222,0.00016265445,0.00014759463],"domain_scores_gemma":[0.9995644,0.000061795945,0.00002981764,0.00018609907,0.000043555192,0.0001143319],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000035726636,0.00013800467,0.00030103495,0.00006453655,0.000040223094,0.000008159137,0.00005743973,0.00007344443,0.0010169864],"category_scores_gemma":[0.000005802129,0.000105238316,0.00009555259,0.00007766063,0.00012171964,0.000048042028,0.000053912747,0.000061590334,0.0000070277624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010802209,0.0014420183,0.029829802,0.006121119,0.00061358884,0.00018458771,0.0033981397,0.000028638098,0.9246239,0.0025784448,0.0009643976,0.029135121],"study_design_scores_gemma":[0.0008117908,0.00029083923,0.07557364,0.0006246577,0.00017672755,0.000009920623,0.0005520838,0.0006285875,0.91879165,0.00031466936,0.0020941629,0.00013125503],"about_ca_topic_score_codex":0.0002243082,"about_ca_topic_score_gemma":0.0000127518915,"teacher_disagreement_score":0.08288601,"about_ca_system_score_codex":0.000013790113,"about_ca_system_score_gemma":0.000043254717,"threshold_uncertainty_score":0.9998962},"labels":[],"label_agreement":null},{"id":"W4399740896","doi":"10.1016/j.bbrep.2024.101752","title":"Autophagy unraveled: Navigating cell fate and disease dynamics","year":2024,"lang":"en","type":"editorial","venue":"Biochemistry and Biophysics Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Children's Hospital Research Institute of Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"","keywords":"Autophagy; Cell fate determination; Biology; Cell biology; Computational biology; Disease; Genetics; Transcription factor; Apoptosis; Medicine; Gene","score_opus":0.003884244255847554,"score_gpt":0.2589413471256176,"score_spread":0.25505710286977007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399740896","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6474698,0.023245102,0.000021698563,0.00027026795,0.32495847,0.00058251293,0.0011044237,0.0003438355,0.0020038933],"genre_scores_gemma":[0.54484856,0.002327723,0.000117898664,0.00011454825,0.43559045,0.000052260864,0.005581241,0.00014795453,0.011219335],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99762344,0.000013119242,0.00048868055,0.0009936059,0.0005541022,0.00032705476],"domain_scores_gemma":[0.9981442,0.00007961361,0.0003283533,0.0005967105,0.00016731331,0.0006837931],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012651747,0.0005301353,0.00057029125,0.000029536553,0.00012542623,0.00013303442,0.00006885581,0.00065931753,0.000016057944],"category_scores_gemma":[0.00016008446,0.00047044584,0.00020455862,0.00014225929,0.00022237276,0.00004710687,0.00016646017,0.00094610226,0.0000057694633],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054132915,0.0007690021,0.000362951,0.024373006,0.0009630842,0.036955845,0.000215225,0.0000010228052,0.11076907,0.00007517011,0.8089573,0.016017005],"study_design_scores_gemma":[0.0033595834,0.00060049706,0.00040603548,0.012360566,0.007311626,0.0009816013,0.00030781562,0.0026654603,0.53394496,0.017433334,0.41609344,0.004535081],"about_ca_topic_score_codex":0.000026390011,"about_ca_topic_score_gemma":2.3180898e-7,"teacher_disagreement_score":0.4231759,"about_ca_system_score_codex":0.00010787695,"about_ca_system_score_gemma":0.0008983816,"threshold_uncertainty_score":0.99977475},"labels":[],"label_agreement":null},{"id":"W4399850192","doi":"10.1007/s12032-024-02417-2","title":"Dissecting the multifaceted roles of autophagy in cancer initiation, growth, and metastasis: from molecular mechanisms to therapeutic applications","year":2024,"lang":"en","type":"article","venue":"Medical Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Autophagy; Biology; Tumor microenvironment; Context (archaeology); Carcinogenesis; Cancer research; Cancer; Cell biology; Cancer cell; Immunology; Immune system; Apoptosis; Genetics","score_opus":0.019543037517276787,"score_gpt":0.3643738667088487,"score_spread":0.34483082919157193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399850192","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9209284,0.017077565,0.03599516,0.024218459,0.00025508367,0.0010373252,0.000034614975,0.00007908856,0.00037429944],"genre_scores_gemma":[0.9940238,0.00037663808,0.00052123185,0.0042557013,0.00011468275,0.0006597724,0.000016939803,0.000016061878,0.000015170062],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894077,0.00011584995,0.00030285027,0.0002280165,0.0002615562,0.00015095342],"domain_scores_gemma":[0.99914896,0.00045831656,0.000043759755,0.00014818594,0.000054399025,0.00014637133],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003174586,0.000098478,0.00028074795,0.000099356446,0.000035069068,0.0000073492506,0.000107060056,0.0001334485,0.0003871003],"category_scores_gemma":[0.00020201351,0.00006425789,0.00004989039,0.00031693187,0.00009759759,0.00002480486,0.000042324835,0.00023022962,0.0000079339125],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035487453,0.0010197575,0.0013913179,0.00030399568,0.0013381888,0.00066063384,0.008443524,0.000037717567,0.23890933,0.07960634,0.00012936111,0.66780496],"study_design_scores_gemma":[0.00924548,0.0023151278,0.09500572,0.0016997642,0.0024334483,0.00018681712,0.0076110456,0.026172275,0.63116944,0.19223459,0.031078847,0.0008474412],"about_ca_topic_score_codex":0.00023141077,"about_ca_topic_score_gemma":0.00015201012,"teacher_disagreement_score":0.6669575,"about_ca_system_score_codex":0.00005469044,"about_ca_system_score_gemma":0.00030864854,"threshold_uncertainty_score":0.42384768},"labels":[],"label_agreement":null},{"id":"W4400042874","doi":"10.1080/15548627.2024.2369436","title":"Last but not least: emerging roles of the autophagy-related protein ATG4D","year":2024,"lang":"en","type":"review","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Autophagy; Cell biology; Computational biology; Genetics; Apoptosis","score_opus":0.026563348925105316,"score_gpt":0.3283996376781976,"score_spread":0.30183628875309226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400042874","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0030271932,0.9897165,0.0000062041718,0.00016832899,0.0011034118,0.002620495,0.00017544946,0.0003790544,0.0028034064],"genre_scores_gemma":[0.0048806276,0.9643607,0.00006634754,0.00028840563,0.0005802119,0.00041987016,0.00009858305,0.00031269036,0.028992563],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9957246,0.0002935266,0.0015642217,0.0009074518,0.0008440928,0.0006661147],"domain_scores_gemma":[0.99722785,0.000102271966,0.0007554603,0.0015409581,0.0001248292,0.00024864057],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00039570764,0.00095719314,0.0027445308,0.00039281024,0.00016474228,0.000051348536,0.0007794116,0.0007570148,0.0008567728],"category_scores_gemma":[0.00013070686,0.00058190385,0.0022364275,0.0011140733,0.00031837655,0.00009348628,0.00037146945,0.0014056066,0.0010330407],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004859873,0.0003279907,0.0000020300909,0.031608302,0.0026782514,0.0005034228,0.0003249477,0.0000023459866,0.0006022429,0.005572357,0.0013806174,0.9569489],"study_design_scores_gemma":[0.0008408663,0.00016209284,0.00006197437,0.038302302,0.0055651604,0.0003146963,0.000037849837,0.00007688427,0.0048967493,0.00052002503,0.9486458,0.0005756206],"about_ca_topic_score_codex":0.000028106939,"about_ca_topic_score_gemma":0.000005198614,"teacher_disagreement_score":0.9563733,"about_ca_system_score_codex":0.00021061154,"about_ca_system_score_gemma":0.0013294942,"threshold_uncertainty_score":0.9997448},"labels":[],"label_agreement":null},{"id":"W4400220022","doi":"10.1101/2024.06.26.600741","title":"Unlocking a New Path: An Autophagometer that Measures Flux Using a Non-Fluorescent Immunohistochemistry Method","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"","keywords":"Autophagy; Computer science; Process (computing); Fluorescence microscope; Immunohistochemistry; Flux (metallurgy); Fluorescence; Computational biology; Biology; Pathology; Chemistry; Medicine; Biochemistry; Physics","score_opus":0.03363121404830026,"score_gpt":0.30305619162243996,"score_spread":0.2694249775741397,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400220022","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96193033,0.016965589,0.016365286,0.0001893395,0.0021240471,0.0013569089,0.00017455718,0.00086681166,0.000027141426],"genre_scores_gemma":[0.9628805,0.00020541892,0.034069557,0.0006124056,0.0016053031,0.00014012543,0.0000028052295,0.0004263259,0.000057566936],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99521434,0.00017844023,0.00081166596,0.0018327155,0.0010265186,0.0009363015],"domain_scores_gemma":[0.995488,0.00005941771,0.00045483233,0.0025805577,0.00041851183,0.0009987191],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000844927,0.0011357614,0.0013094627,0.00048379932,0.00018770664,0.00037682732,0.0006798069,0.0010468726,0.0002553728],"category_scores_gemma":[0.00013287863,0.001127083,0.0006657536,0.0006110994,0.00013278083,0.00015627907,0.00076544425,0.0019647933,0.00009283408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021063817,0.0003091399,0.00067406084,0.0014094764,0.0010847296,0.0008963889,0.00008536604,0.00007690716,0.9947074,0.00005150915,0.00044426366,0.00005013081],"study_design_scores_gemma":[0.0015023095,0.000118492746,0.011010876,0.003138401,0.0016484527,7.960527e-7,0.000010633232,0.006207076,0.97339123,0.00003254667,0.0016724465,0.0012667158],"about_ca_topic_score_codex":0.00019595798,"about_ca_topic_score_gemma":3.4856143e-7,"teacher_disagreement_score":0.021316135,"about_ca_system_score_codex":0.0010549092,"about_ca_system_score_gemma":0.0034780772,"threshold_uncertainty_score":0.9991179},"labels":[],"label_agreement":null},{"id":"W4400538586","doi":"10.12688/f1000research.132628.2","title":"The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence","year":2024,"lang":"en","type":"preprint","venue":"F1000Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Genentech; Mitacs; Motor Neurone Disease Association; Government of Canada; Ontario Genomics Institute; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Bayer; ALS Society of Canada; Ontario Genomics; Genome Canada; Bristol-Myers Squibb; Pfizer; ALS Association","keywords":"Sequestosome 1; Western blot; Immunofluorescence; Antibody; Biology; Immunoprecipitation; Neurodegeneration; Amyotrophic lateral sclerosis; Cell biology; Immunology; Medicine; Pathology; Biochemistry; Gene; Disease; Immunoglobulin light chain","score_opus":0.05252832896796798,"score_gpt":0.38651420809533477,"score_spread":0.33398587912736677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400538586","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98170245,0.013079209,0.0005705836,0.0007409515,0.00038520896,0.00320994,0.00026518307,0.000036464593,0.000010035206],"genre_scores_gemma":[0.98900765,0.006273973,0.00084913097,0.000017590328,0.00014408979,0.0012068191,0.00031064183,0.000056558543,0.002133537],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99823534,0.0000772059,0.00061779364,0.00040092337,0.00036480537,0.0003039378],"domain_scores_gemma":[0.99778944,0.0009958806,0.00016025422,0.0005536892,0.0004504045,0.00005030926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014515615,0.00017655543,0.00033676793,0.0003018265,0.00014839528,0.0001845167,0.00024662525,0.00017730838,0.0000034564246],"category_scores_gemma":[0.00046765397,0.00013217959,0.00011827708,0.00013756976,0.00025042787,0.00010337276,0.00034112998,0.00043735706,0.0000044377057],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.014366669,0.00089136953,0.054142307,0.029374214,0.0023175548,0.000044412594,0.013138694,0.0002829353,0.6479983,0.018173968,0.0026239292,0.21664566],"study_design_scores_gemma":[0.00489082,0.0010985245,0.46445537,0.0059620207,0.0005184016,0.000018634211,0.0012578728,0.030494574,0.3862696,0.10172482,0.0026657265,0.00064362976],"about_ca_topic_score_codex":0.00038138262,"about_ca_topic_score_gemma":0.000058023237,"teacher_disagreement_score":0.41031307,"about_ca_system_score_codex":0.00011094156,"about_ca_system_score_gemma":0.00032782956,"threshold_uncertainty_score":0.53901273},"labels":[],"label_agreement":null},{"id":"W4400582752","doi":"10.1002/advs.202406473","title":"Otilonium Bromide Exhibits Potent Antifungal Effects by Blocking Ergosterol Plasma Membrane Localization and Triggering Cytotoxic Autophagy in <i>Candida Albicans</i>","year":2024,"lang":"en","type":"article","venue":"Advanced Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"National Key Research and Development Program of China; Shanghai Municipal Education Commission; National Natural Science Foundation of China","keywords":"Candida albicans; Autophagy; Cytotoxic T cell; Ergosterol; Blocking (statistics); Chemistry; Membrane; Antifungal; Corpus albicans; Cytotoxicity; Microbiology; Pharmacology; Biology; Biochemistry; In vitro; Apoptosis","score_opus":0.0038055915728006573,"score_gpt":0.25451329950370133,"score_spread":0.2507077079309007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400582752","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912914,0.0045431084,0.002584464,0.0001492348,0.0004072421,0.00054785045,0.0000071415343,0.0001618343,0.00030769984],"genre_scores_gemma":[0.9982045,0.00061167165,0.0003098015,0.00051990105,0.00004709668,0.000038994716,0.000007686989,0.000028030463,0.00023231034],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980764,0.000035412213,0.0002822501,0.0006640978,0.00046365042,0.00047823123],"domain_scores_gemma":[0.9992852,0.00013732981,0.000051479416,0.00024377956,0.000040859875,0.00024135312],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003172943,0.00021397517,0.00029292965,0.00027762176,0.00017504768,0.00010482529,0.00014883104,0.00006376938,0.000020102627],"category_scores_gemma":[0.000100303034,0.00018869912,0.000046642028,0.001035784,0.00029694667,0.0005606625,0.00006500206,0.0002043303,0.00001027261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014789759,0.00006846593,0.0006684843,0.00032399796,0.000014584279,0.00029188377,0.00028133672,0.0010099914,0.973064,0.00012367842,0.000027813525,0.02397784],"study_design_scores_gemma":[0.0018962286,0.00024474648,0.0047491537,0.0011166069,0.000032035514,0.00010826544,0.000032347718,0.05205811,0.9387857,0.000119112185,0.0006490531,0.0002086844],"about_ca_topic_score_codex":0.000027825137,"about_ca_topic_score_gemma":0.000009937706,"teacher_disagreement_score":0.05104812,"about_ca_system_score_codex":0.00017261787,"about_ca_system_score_gemma":0.00020440923,"threshold_uncertainty_score":0.7694927},"labels":[],"label_agreement":null},{"id":"W4400584998","doi":"10.3390/cells13141186","title":"Advancements in Utilizing Natural Compounds for Modulating Autophagy in Liver Cancer: Molecular Mechanisms and Therapeutic Targets","year":2024,"lang":"en","type":"review","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences; Korea Health Industry Development Institute; National Research Foundation of Korea; Ministry of Science and ICT, South Korea; Kyung Hee University; National Research Foundation","keywords":"Autophagy; Cancer; Epigenetics; Cancer research; Cancer cell; Biology; Liver cancer; Medicine; Bioinformatics; Hepatocellular carcinoma; Internal medicine; Apoptosis; Biochemistry","score_opus":0.04060062154109761,"score_gpt":0.3695157621549236,"score_spread":0.328915140613826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400584998","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00060181005,0.99674743,0.00015654083,0.000011947028,0.0005734681,0.0017321182,0.000037628233,0.000038779996,0.00010027188],"genre_scores_gemma":[0.015216905,0.9827216,0.0008154375,0.00027627507,0.00007694822,0.00038614945,0.00009374284,0.00009510545,0.00031779465],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99838066,0.00006268563,0.00048636433,0.0005218681,0.00017432468,0.00037412596],"domain_scores_gemma":[0.99946713,0.000075824064,0.00013171694,0.00022042262,0.000024423585,0.00008048143],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016526421,0.00039979749,0.0011976764,0.0002699279,0.000032629287,0.000026490243,0.000113543545,0.00020216318,0.000037758913],"category_scores_gemma":[0.000006692659,0.00032494418,0.00025072804,0.00025397132,0.00003250648,0.000040948627,0.00006041607,0.00041794713,0.000009171739],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034068667,0.00011093167,0.0000018988536,0.02418815,0.00031646673,0.00041628315,0.00022575095,0.000010921873,0.0012400176,0.0007786548,0.000027922972,0.9726489],"study_design_scores_gemma":[0.0060060723,0.00045460887,0.00006066285,0.09189654,0.0046435916,0.00008236255,0.0001749747,0.027050551,0.005627512,0.009122122,0.8530104,0.0018705896],"about_ca_topic_score_codex":0.000026419257,"about_ca_topic_score_gemma":0.000009007515,"teacher_disagreement_score":0.97077835,"about_ca_system_score_codex":0.00025554633,"about_ca_system_score_gemma":0.00018265209,"threshold_uncertainty_score":0.99992025},"labels":[],"label_agreement":null},{"id":"W4400649864","doi":"10.1007/s00018-024-05337-6","title":"Truncated tau interferes with the autophagy and endolysosomal pathway and results in lipid accumulation","year":2024,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; Motor Neurone Disease Association; European Commission; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas; King's College London; Instituto de Salud Carlos III; Alzheimer Society; Alzheimer's Society","keywords":"Tauopathy; TFEB; Autophagy; Cell biology; Biology; Biogenesis; Endosome; Transcription factor; Lysosome; Intracellular; Neurodegeneration; Biochemistry; Disease; Gene; Internal medicine; Medicine","score_opus":0.021460083083114506,"score_gpt":0.2804555395929415,"score_spread":0.258995456509827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400649864","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9735393,0.023106359,0.00036128276,0.0020680255,0.000058126614,0.00021505974,0.0000043256164,0.0000346,0.0006129064],"genre_scores_gemma":[0.9989221,0.00034703308,0.00009310279,0.00047044182,0.000050086343,0.000009209333,0.000008114272,0.000008074108,0.000091857626],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911594,0.000056948888,0.0001511903,0.00033660204,0.00018138751,0.00015794074],"domain_scores_gemma":[0.999668,0.00006815995,0.000028525064,0.00011068474,0.000016833117,0.0001078105],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003549517,0.000115500145,0.00013527727,0.00011167827,0.000111195746,0.000105721345,0.000058374426,0.000044634362,0.000007628068],"category_scores_gemma":[0.00005121215,0.00006429271,0.000021658216,0.0002636236,0.00042834808,0.000107554704,0.000039364764,0.00010667953,0.0000012650811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012979478,0.00019220974,0.0059882463,0.000417543,0.00024962114,0.0016191303,0.0081136795,0.00010567862,0.88442445,0.016688818,0.00035057936,0.0805521],"study_design_scores_gemma":[0.008122419,0.003254703,0.09625558,0.0011911726,0.00033683618,0.00042129093,0.0039688884,0.053475197,0.8105203,0.0024624728,0.019142644,0.0008484952],"about_ca_topic_score_codex":0.000035348094,"about_ca_topic_score_gemma":0.000007949376,"teacher_disagreement_score":0.09026733,"about_ca_system_score_codex":0.0000061154424,"about_ca_system_score_gemma":0.00010991033,"threshold_uncertainty_score":0.26217806},"labels":[],"label_agreement":null},{"id":"W4400651339","doi":"10.1080/15548627.2024.2373676","title":"Key considerations for investigating and interpreting autophagy in skeletal muscle","year":2024,"lang":"en","type":"review","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Autophagy; Skeletal muscle; Key (lock); Cell biology; Computational biology; Neuroscience; Anatomy; Genetics; Ecology; Apoptosis","score_opus":0.06820480650124798,"score_gpt":0.38607730374374916,"score_spread":0.31787249724250116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400651339","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008691355,0.99537665,0.000047254573,0.00016719784,0.00048587058,0.0018215186,0.00010362639,0.00023099924,0.0008977764],"genre_scores_gemma":[0.0037432532,0.9900817,0.0029623641,0.0008173016,0.000444181,0.00075807306,0.00016864022,0.0001750434,0.0008494227],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974624,0.00013361147,0.0009838694,0.0007627274,0.00019289656,0.00046452013],"domain_scores_gemma":[0.9982006,0.00086244463,0.00023302516,0.0004032891,0.00005744347,0.00024319155],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042385567,0.00055943604,0.001731296,0.00044403275,0.000124531,0.00012100776,0.00010764183,0.00041730216,0.00015395484],"category_scores_gemma":[0.0008136061,0.00046742457,0.0005249535,0.0003236389,0.00017599626,0.00011213588,0.00012361753,0.0006809022,0.000076635275],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000040598907,0.00011156619,0.0000035575413,0.030983448,0.0004993837,0.00047067125,0.0011146951,8.4178726e-7,0.000038595233,0.010846834,0.0018677035,0.95405865],"study_design_scores_gemma":[0.0010540716,0.00024479677,0.000066415465,0.032063436,0.0024302802,0.00046129082,0.000070814145,0.0012233391,0.000057302892,0.010729986,0.9509453,0.0006529449],"about_ca_topic_score_codex":0.000025790794,"about_ca_topic_score_gemma":0.000012261057,"teacher_disagreement_score":0.9534057,"about_ca_system_score_codex":0.00016380336,"about_ca_system_score_gemma":0.0008079292,"threshold_uncertainty_score":0.99977773},"labels":[],"label_agreement":null},{"id":"W4400687200","doi":"10.20944/preprints202407.1193.v1","title":"Gaining Insight into Mitochondrial Targeting: AUTAC-Biguanide as an Anticancer Agent","year":2024,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Biguanide; Mitophagy; Metformin; Mitochondrion; Chemistry; Pharmacology; Cancer cell; Mechanism (biology); Cancer; Biochemistry; Autophagy; Biology; Medicine; Apoptosis; Internal medicine; Diabetes mellitus; Endocrinology","score_opus":0.09069971425561639,"score_gpt":0.3937153359308983,"score_spread":0.3030156216752819,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400687200","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9614987,0.002912802,0.0000726923,0.0011169993,0.0047134296,0.0013360629,0.000024963152,0.0007996707,0.027524726],"genre_scores_gemma":[0.9878034,0.000840206,0.000992,0.001513719,0.003497333,0.00037079802,0.0003196665,0.00021274689,0.004450138],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9952875,0.00021542366,0.00094518857,0.0020105466,0.0008771674,0.00066421484],"domain_scores_gemma":[0.9965992,0.000076583514,0.00032011457,0.0020473069,0.00024615778,0.0007106492],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0005167106,0.00075538165,0.0010158934,0.00034013417,0.0001743188,0.00008273523,0.00065696565,0.0007024295,0.0053450866],"category_scores_gemma":[0.00047318038,0.00071103586,0.0005418611,0.00028146326,0.00020215308,0.00011346616,0.0023030431,0.0022144027,0.005305197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0052733268,0.0034882864,0.22075887,0.005991143,0.007149142,0.0072588692,0.06322306,0.00089428347,0.6605224,0.009134203,0.0029115062,0.013394946],"study_design_scores_gemma":[0.0050932975,0.0005788393,0.12364807,0.0048148264,0.002818148,0.00014445662,0.0010730383,0.0025935734,0.61170155,0.08901972,0.15552752,0.0029869932],"about_ca_topic_score_codex":0.00052454986,"about_ca_topic_score_gemma":0.000010778855,"teacher_disagreement_score":0.15261601,"about_ca_system_score_codex":0.0004558569,"about_ca_system_score_gemma":0.0013726052,"threshold_uncertainty_score":0.9995341},"labels":[],"label_agreement":null},{"id":"W4400856221","doi":"10.1016/j.arr.2024.102428","title":"Autophagy in aging-related diseases and cancer: Principles, regulatory mechanisms and therapeutic potential","year":2024,"lang":"en","type":"review","venue":"Ageing Research Reviews","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"BC Cancer Foundation; Canadian Institutes of Health Research; Mitacs; Ministry of Education - Singapore; National Research Foundation Singapore; Terry Fox Research Institute; Canadian Cancer Society; Lotte and John Hecht Memorial Foundation","keywords":"Autophagy; Cancer; Neuroscience; Biology; Medicine; Computational biology; Genetics; Apoptosis","score_opus":0.12332189484309476,"score_gpt":0.4412098658338377,"score_spread":0.31788797099074295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400856221","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00057527004,0.9952992,0.000004083782,0.00013978999,0.00023150424,0.0034829574,0.0000372281,0.00009823022,0.00013169048],"genre_scores_gemma":[0.0004879018,0.9951665,0.00004905537,0.00010876174,0.00024776906,0.0009223564,0.00006330938,0.00014070043,0.0028136491],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99521285,0.0012216916,0.0010832988,0.0010504046,0.00069378654,0.00073795236],"domain_scores_gemma":[0.9982605,0.00021238325,0.00021500376,0.00077686773,0.00007149945,0.00046374032],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002364322,0.00058970595,0.002587557,0.00081175735,0.00017790971,0.00014295623,0.00027171714,0.00036582147,0.00019446504],"category_scores_gemma":[0.0001831486,0.00039889314,0.00047203264,0.0009786957,0.0003245941,0.00007819654,0.00035923763,0.0016285618,0.0001078612],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013655829,0.000072235925,0.000008751323,0.0573706,0.00032114194,0.0019179339,0.00008385665,2.018171e-7,0.000012551938,0.0018729018,0.00032791498,0.93799824],"study_design_scores_gemma":[0.00045454717,0.00011587851,0.00053240947,0.08205923,0.0019818016,0.00015538686,0.0000117373775,0.00010882917,0.0000022912338,0.0023545872,0.91188794,0.0003353619],"about_ca_topic_score_codex":0.00009879485,"about_ca_topic_score_gemma":0.00001126148,"teacher_disagreement_score":0.9376629,"about_ca_system_score_codex":0.00032875407,"about_ca_system_score_gemma":0.00082565483,"threshold_uncertainty_score":0.9998463},"labels":[],"label_agreement":null},{"id":"W4401151872","doi":"10.1101/2024.07.29.605699","title":"Understanding the Pathogenicity of Parkin Catalytic Domain Mutants","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Parkin; Mitophagy; Ubiquitin; PINK1; Ubiquitin ligase; Mutant; Mutation; In silico; Biology; Autophagy; Cell biology; Mitochondrion; Genetics; Parkinson's disease; Disease; Gene; Medicine","score_opus":0.03872284575728261,"score_gpt":0.2547997215222179,"score_spread":0.2160768757649353,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401151872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98814654,0.0068011587,0.0014788137,0.00053334696,0.0011295544,0.0010662463,0.00046762644,0.00029642473,0.000080284284],"genre_scores_gemma":[0.99826753,0.00035098416,0.00038850086,0.00030197445,0.00044676216,0.00009584862,5.90452e-7,0.00013917014,0.000008667444],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99746037,0.0001239523,0.00060992135,0.0007603184,0.0005757743,0.00046967404],"domain_scores_gemma":[0.99755555,0.00010728021,0.0003371493,0.0015670363,0.00017613785,0.0002568385],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00075874024,0.00049576274,0.00072156766,0.00023325477,0.00013056623,0.00008338797,0.0004329274,0.00043762766,0.0000918842],"category_scores_gemma":[0.00009798882,0.0003769849,0.00038409609,0.0004857433,0.00029736912,0.000039195253,0.0005093296,0.00102958,0.00009001072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039456016,0.00053786085,0.005790318,0.0040766406,0.0030476628,0.0014359815,0.00018742609,0.00003984132,0.96700317,0.016458701,0.0010232149,0.0000046462533],"study_design_scores_gemma":[0.0036289985,0.000371413,0.1318986,0.0058335816,0.004890645,6.770591e-7,0.00014111483,0.0015107085,0.84444124,0.0025312074,0.0025948423,0.002156961],"about_ca_topic_score_codex":0.000022971439,"about_ca_topic_score_gemma":0.0000014798338,"teacher_disagreement_score":0.12610829,"about_ca_system_score_codex":0.00052819727,"about_ca_system_score_gemma":0.0011033742,"threshold_uncertainty_score":0.9998682},"labels":[],"label_agreement":null},{"id":"W4401173915","doi":"10.1016/j.molcel.2024.07.003","title":"The V-ATPase/ATG16L1 axis is controlled by the V1H subunit","year":2024,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Medical Research Council; Francis Crick Institute; Cancer Research UK; Wellcome Trust","keywords":"Biology; Cell biology; Autophagy; Organelle; ATG16L1; Ubiquitin; Protein subunit; ATG8; ATPase; Membrane; Biophysics; Biochemistry; Enzyme; Gene","score_opus":0.004695814188045361,"score_gpt":0.24432521132197152,"score_spread":0.23962939713392617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401173915","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5849519,0.25955144,0.002379199,0.051073577,0.00088337634,0.0022108816,0.00007205957,0.00037565213,0.098501965],"genre_scores_gemma":[0.96097445,0.0006993045,0.000011981552,0.008098297,0.0001093385,0.00008832052,0.00002155668,0.00004439622,0.029952375],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988961,0.000095815085,0.00019435186,0.00022872612,0.00031603576,0.0002689423],"domain_scores_gemma":[0.9990899,0.00017139885,0.000032312677,0.00055570045,0.000043892243,0.00010681068],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024412804,0.00016580972,0.00020775205,0.000029110211,0.00018696967,0.00010399357,0.00019858782,0.00007225964,0.0004959825],"category_scores_gemma":[0.000025082894,0.00008141859,0.00030564537,0.00014875385,0.000109514134,0.000023375867,0.000032613432,0.00024568642,0.0005258018],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017994879,0.0004905626,0.0001172797,0.00022511647,0.0020224766,0.0023457643,0.0018495567,0.000009466727,0.30865353,0.0066044643,0.63814664,0.03773563],"study_design_scores_gemma":[0.0032540262,0.00015167362,0.00004472235,0.00003880865,0.0003556685,0.000017472503,0.00011099517,0.0012970284,0.18003957,0.0015828706,0.81296897,0.00013819375],"about_ca_topic_score_codex":0.000028677297,"about_ca_topic_score_gemma":0.0000013192027,"teacher_disagreement_score":0.37602258,"about_ca_system_score_codex":0.000029005754,"about_ca_system_score_gemma":0.00010106952,"threshold_uncertainty_score":0.67582935},"labels":[],"label_agreement":null},{"id":"W4401209608","doi":"10.3390/biom14080922","title":"Complex Interplay between DNA Damage and Autophagy in Disease and Therapy","year":2024,"lang":"en","type":"review","venue":"Biomolecules","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Heart and Stroke Foundation of Canada","keywords":"Autophagy; DNA damage; Context (archaeology); Biology; DNA repair; Cancer; Disease; Cancer research; Programmed cell death; Bioinformatics; Medicine; DNA; Genetics; Apoptosis; Internal medicine","score_opus":0.06731449873720582,"score_gpt":0.4105171082510598,"score_spread":0.34320260951385395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401209608","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0067007346,0.9917107,0.000008060171,0.00018452079,0.00007194983,0.000829082,0.00026592574,0.00008653927,0.00014244657],"genre_scores_gemma":[0.0042420835,0.99441123,0.000046321948,0.00028575317,0.00021718253,0.000075582844,0.00042487876,0.00008408373,0.0002128931],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99850184,0.00011591992,0.0004156366,0.000550063,0.00016272461,0.00025382213],"domain_scores_gemma":[0.99913573,0.00007861226,0.000087096254,0.00034893255,0.000014717655,0.0003349225],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011404676,0.0004540414,0.0012420792,0.00036027154,0.000035481396,0.00007201661,0.00012203044,0.00018678073,0.00007442387],"category_scores_gemma":[0.000017988934,0.00031618326,0.00023554561,0.0002525833,0.00027074272,0.000038111775,0.00011795988,0.00025513803,0.000043608015],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050732328,0.00009299377,0.00008749922,0.011306197,0.00055457343,0.0012561072,0.00010817126,1.68107e-9,0.000052452924,0.00037737837,0.0006268799,0.985487],"study_design_scores_gemma":[0.00080232054,0.00014817415,0.0037614559,0.011459935,0.0014354981,0.000042403124,0.000012573841,0.000010606681,0.000020009968,0.00041528282,0.9815133,0.00037842293],"about_ca_topic_score_codex":0.000017807377,"about_ca_topic_score_gemma":0.0000019837782,"teacher_disagreement_score":0.9851086,"about_ca_system_score_codex":0.00004219105,"about_ca_system_score_gemma":0.00019020442,"threshold_uncertainty_score":0.999929},"labels":[],"label_agreement":null},{"id":"W4401388494","doi":"10.1016/j.biopha.2024.117278","title":"Empagliflozin mitigates ponatinib-induced cardiotoxicity by restoring the connexin 43-autophagy pathway","year":2024,"lang":"en","type":"article","venue":"Biomedicine & Pharmacotherapy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministero dell'Istruzione e del Merito; Research and Development Corporation of Newfoundland and Labrador; Ministero dell’Istruzione, dell’Università e della Ricerca; European Commission","keywords":"Cardiotoxicity; Empagliflozin; Autophagy; Ponatinib; Medicine; Pharmacology; Chemistry; Cancer research; Internal medicine; Apoptosis; Chemotherapy; Dasatinib; Endocrinology; Myeloid leukemia; Biochemistry; Diabetes mellitus","score_opus":0.022471710897160088,"score_gpt":0.3348534077917863,"score_spread":0.3123816968946262,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401388494","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91577333,0.06777732,0.00016942588,0.009377567,0.002333073,0.0011951171,0.00013917024,0.0006390128,0.0025960137],"genre_scores_gemma":[0.9802894,0.003326157,0.000059699945,0.009331522,0.002962706,0.00019450164,0.00010761408,0.00014926096,0.0035791437],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99690175,0.00020777283,0.0006216118,0.00072394137,0.0008596686,0.00068526185],"domain_scores_gemma":[0.99822557,0.00042755512,0.000110658446,0.0006517106,0.000108573826,0.00047591157],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007824547,0.0005315672,0.00066539133,0.00028772946,0.0002568257,0.000088539724,0.00037739848,0.0001850066,0.0021009787],"category_scores_gemma":[0.000050215855,0.00033745708,0.00038555122,0.00089243974,0.00032424714,0.0001673202,0.00003989096,0.0006257145,0.00020216979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003729212,0.00020737274,0.00028450656,0.00014104511,0.0009063263,0.00037260706,0.0010571122,6.680953e-7,0.8901549,0.00028256277,0.055969447,0.050250523],"study_design_scores_gemma":[0.0033142348,0.0005197605,0.0012929345,0.00030423893,0.00020503064,0.0001287992,0.00016481023,0.0005699036,0.6036703,0.00013357111,0.38938692,0.00030948917],"about_ca_topic_score_codex":0.00013427145,"about_ca_topic_score_gemma":0.0000014193555,"teacher_disagreement_score":0.33341748,"about_ca_system_score_codex":0.00020152776,"about_ca_system_score_gemma":0.00036245977,"threshold_uncertainty_score":0.99990773},"labels":[],"label_agreement":null},{"id":"W4401406874","doi":"10.1016/j.nbd.2024.106625","title":"Disease-associated mutations in C-terminus of HSP70 interacting protein (CHIP) impair its ability to negatively regulate mitophagy","year":2024,"lang":"en","type":"article","venue":"Neurobiology of Disease","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; University of Toronto; University Health Network; Canada Research Chairs","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Parkin; PINK1; Biology; Ubiquitin ligase; Cell biology; Mitochondrion; Ubiquitin; Autophagy; Genetics; Parkinson's disease; Gene; Disease; Apoptosis; Medicine","score_opus":0.01738937741301628,"score_gpt":0.3102401961394339,"score_spread":0.2928508187264176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401406874","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961712,0.00048364414,0.0000074497107,0.0013105745,0.00023323974,0.0012036576,0.0004160858,0.00010158455,0.000072559444],"genre_scores_gemma":[0.9991042,0.000009344386,0.000045637047,0.00026882286,0.000049510036,0.00012984942,0.000120180535,0.000032667645,0.00023980976],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99818695,0.0002894098,0.0005871158,0.00049146794,0.00014481918,0.00030024743],"domain_scores_gemma":[0.9986205,0.00031131986,0.00015283063,0.0003528762,0.0001419079,0.00042053766],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017352233,0.00022128511,0.0004450737,0.00028978856,0.000038457623,0.0000089287005,0.00014835347,0.00007936666,0.00017446086],"category_scores_gemma":[0.001107194,0.00019997329,0.00024648078,0.00047752986,0.00018148567,0.00011756621,0.00007067992,0.0002202479,0.000025226143],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.014866403,0.0063793208,0.21255262,0.0048088348,0.0007328739,0.0017410511,0.0031247605,0.0007308349,0.746345,0.0010742644,0.0006769869,0.0069670966],"study_design_scores_gemma":[0.0012768676,0.0005601158,0.9567789,0.0010210052,0.00019252663,0.000002453586,0.000053396063,0.000730531,0.037971888,0.0011784657,0.00004849986,0.00018534453],"about_ca_topic_score_codex":0.000022108385,"about_ca_topic_score_gemma":0.000008513273,"teacher_disagreement_score":0.7442263,"about_ca_system_score_codex":0.000076806915,"about_ca_system_score_gemma":0.00041577342,"threshold_uncertainty_score":0.8154674},"labels":[],"label_agreement":null},{"id":"W4401478637","doi":"10.1101/2024.08.09.607348","title":"Assessing Autophagy Flux in Glioblastoma Temozolomide Resistant Cells","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Temozolomide; Autophagy; Glioblastoma; Flux (metallurgy); Cancer research; Medicine; Chemistry; Biology; Genetics; Apoptosis","score_opus":0.01431495481219935,"score_gpt":0.26420226855111884,"score_spread":0.24988731373891948,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401478637","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98705596,0.008119133,0.00007798939,0.00037680852,0.002128538,0.0010807696,0.00014437002,0.0009110976,0.00010535095],"genre_scores_gemma":[0.99596274,0.0002564502,0.0016812113,0.0005866884,0.0008836538,0.00023247053,4.6633178e-7,0.00031219964,0.000084132786],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9956618,0.00018787006,0.0010114932,0.001557086,0.0006858248,0.000895935],"domain_scores_gemma":[0.996963,0.00010687297,0.00035264433,0.0017744472,0.00028280844,0.00052022916],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00076976663,0.0008660199,0.0011902653,0.00087227556,0.00011779305,0.0004647542,0.00047091805,0.0009270781,0.00027211828],"category_scores_gemma":[0.00014249045,0.0008715505,0.00040248,0.0009705506,0.00017900894,0.00017780263,0.0006722379,0.0019908152,0.0005193237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032408308,0.00038560628,0.00054974714,0.002047077,0.00036398548,0.004260936,0.000021879008,0.000036790676,0.9902784,0.0005406202,0.0011817579,0.000009110829],"study_design_scores_gemma":[0.001400218,0.00017567011,0.047326334,0.003299538,0.0004577268,1.1952079e-7,0.000011517713,0.0009086805,0.94196033,0.000041170715,0.0034816747,0.00093701424],"about_ca_topic_score_codex":0.00005619128,"about_ca_topic_score_gemma":0.000004471264,"teacher_disagreement_score":0.048318073,"about_ca_system_score_codex":0.00087094656,"about_ca_system_score_gemma":0.0021559398,"threshold_uncertainty_score":0.9993735},"labels":[],"label_agreement":null},{"id":"W4401512039","doi":"10.1101/cshperspect.a041565","title":"Autophagy in Skeletal Muscle","year":2024,"lang":"en","type":"review","venue":"Cold Spring Harbor Perspectives in Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Autophagy; Biology; Mitophagy; Cell biology; Organelle; Mitochondrion; Skeletal muscle; ATG16L1; Lysosome; Flux (metallurgy); Biochemistry; Anatomy; Apoptosis; Chemistry","score_opus":0.037165647276633074,"score_gpt":0.38074491823954876,"score_spread":0.3435792709629157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401512039","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021343373,0.99504167,0.0000061203873,0.000053259453,0.0005731166,0.0009295127,0.000027901968,0.00014150159,0.0010925932],"genre_scores_gemma":[0.019795572,0.9789686,0.00011259843,0.0000548471,0.0004742492,0.00028444972,0.0000068404156,0.00009386953,0.00020892732],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977104,0.00018167916,0.0005764916,0.00092492823,0.00009822381,0.00050827046],"domain_scores_gemma":[0.99906313,0.00013026786,0.00011600826,0.0005441766,0.000030845058,0.00011557429],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026379866,0.00048250143,0.0018060134,0.0008741477,0.000026233141,0.000017831353,0.0002657528,0.0005900747,0.00018493054],"category_scores_gemma":[0.00012446906,0.00039350885,0.0005312049,0.0006681204,0.00023071826,0.00003736856,0.00014514374,0.0010996077,0.00026657464],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000639363,0.0019141755,0.00029868927,0.02708327,0.0016599783,0.0057235304,0.0014436941,0.0000010779231,0.0005305566,0.5677971,0.00019023794,0.39329374],"study_design_scores_gemma":[0.0007003187,0.00019510073,0.002946022,0.009192033,0.0004846948,0.000011498111,0.00008820165,0.000018115188,0.000013806367,0.00030642955,0.98558706,0.00045671503],"about_ca_topic_score_codex":0.00006869005,"about_ca_topic_score_gemma":0.000014924613,"teacher_disagreement_score":0.9853968,"about_ca_system_score_codex":0.00088287675,"about_ca_system_score_gemma":0.00050239736,"threshold_uncertainty_score":0.9998517},"labels":[],"label_agreement":null},{"id":"W4401672060","doi":"10.1007/s12672-024-01240-5","title":"Pediatric cancer—pathology and microenvironment influence: a perspective into osteosarcoma and non-osteogenic mesenchymal malignant neoplasms","year":2024,"lang":"en","type":"review","venue":"Discover Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Eastern Ontario; Stollery Children's Hospital; University of Ottawa","funders":"","keywords":"Tumor microenvironment; Autophagy; Carcinogenesis; Cancer; Biology; Cancer research; Immune system; Osteosarcoma; Stromal cell; Mesenchymal stem cell; Context (archaeology); Tumor progression; Immunology; Medicine; Cell biology; Genetics; Apoptosis","score_opus":0.014578449379593073,"score_gpt":0.3633999993668193,"score_spread":0.34882154998722625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401672060","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14684033,0.85060215,0.000003001585,0.0003460564,0.00040532812,0.00134359,0.00016143953,0.000033126962,0.00026498374],"genre_scores_gemma":[0.0054142317,0.9919588,0.000087781766,0.00049710355,0.000560277,0.00062455004,0.000076571,0.000098694705,0.00068198243],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972797,0.00021272361,0.000635544,0.0011298229,0.00021508071,0.0005270977],"domain_scores_gemma":[0.9987479,0.00016860307,0.00029350148,0.00042743344,0.000040179963,0.00032239227],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018905087,0.000684804,0.002267835,0.00038813657,0.00010611187,0.000040061437,0.0001706588,0.0006870876,0.000113683745],"category_scores_gemma":[0.000033426863,0.0004923107,0.00038560384,0.00028625643,0.00047683314,0.00009247646,0.00040524534,0.0007513296,0.00014776245],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006721926,0.0011053502,0.004082737,0.053188536,0.004231246,0.02607983,0.011188556,0.0000018674745,0.000316901,0.0014560822,0.0025232204,0.89515346],"study_design_scores_gemma":[0.0032509482,0.0035688586,0.0036456154,0.00472609,0.024028942,0.008681944,0.0010856291,0.000009154748,0.000029772604,0.0011540623,0.9486342,0.0011847547],"about_ca_topic_score_codex":0.00020862496,"about_ca_topic_score_gemma":0.000074172895,"teacher_disagreement_score":0.946111,"about_ca_system_score_codex":0.0008801147,"about_ca_system_score_gemma":0.0016510917,"threshold_uncertainty_score":0.9997529},"labels":[],"label_agreement":null},{"id":"W4401733910","doi":"10.21203/rs.3.rs-4601043/v1","title":"HSP60 controls mitochondrial ATP generation for optimal virus-specific IL-21-producing CD4 and cytotoxic CD8 memory T cell responses","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Institut National de la Recherche Scientifique","funders":"","keywords":"Glutaminolysis; Cytotoxic T cell; CD8; Cell biology; Mitochondrion; Autophagy; Biology; T cell; Bioenergetics; T-cell receptor; Chemistry; Biochemistry; Immune system; Metabolism; Immunology; Glycolysis; Apoptosis","score_opus":0.08498305681996353,"score_gpt":0.39501512031149516,"score_spread":0.3100320634915316,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401733910","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95621014,0.031182429,0.0006240632,0.0019151858,0.0013525632,0.006679205,0.0013882044,0.0002087557,0.00043948053],"genre_scores_gemma":[0.96164423,0.0047628437,0.0037718492,0.00022163567,0.012474709,0.0030206114,0.0013634127,0.00028165735,0.012459028],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9950626,0.0005838005,0.00061164255,0.0016107674,0.0012608877,0.00087031425],"domain_scores_gemma":[0.9966205,0.0007766057,0.00012437023,0.0012847169,0.0007263542,0.00046749908],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0017723485,0.00048566514,0.00079671724,0.00076384254,0.0004092282,0.00041729442,0.00029535132,0.00059689756,0.00038725126],"category_scores_gemma":[0.000616888,0.00043192616,0.0003786657,0.00025651924,0.00030013194,0.00008475253,0.00065246184,0.0018468549,0.00017595974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009748898,0.00037317578,0.000030760042,0.0034878808,0.00035843335,0.00045956334,0.0026437119,0.00022752295,0.95051926,0.0002960721,0.027812665,0.004042075],"study_design_scores_gemma":[0.011785281,0.0036337916,0.0013180866,0.0027238503,0.0004237081,0.0000762228,0.0016963143,0.013762652,0.843129,0.0022544877,0.11790378,0.0012928209],"about_ca_topic_score_codex":0.00005583741,"about_ca_topic_score_gemma":0.000011223735,"teacher_disagreement_score":0.10739023,"about_ca_system_score_codex":0.0003876098,"about_ca_system_score_gemma":0.0013522453,"threshold_uncertainty_score":0.99981326},"labels":[],"label_agreement":null},{"id":"W4401797710","doi":"10.1080/15548627.2024.2395725","title":"Function of CSNK2/CK2 selectively affects the endoplasmic reticulum and the Golgi apparatus in mtor-mediated autophagy induction","year":2024,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Deutsche Forschungsgemeinschaft; European Federation of Pharmaceutical Industries and Associations; McGill University","keywords":"Endoplasmic reticulum; Autophagy; Biology; Golgi apparatus; Cell biology; Function (biology); PI3K/AKT/mTOR pathway; ULK1; Signal transduction; Biochemistry; Kinase; Protein kinase A; Apoptosis","score_opus":0.006974088100027377,"score_gpt":0.24245536467019319,"score_spread":0.23548127657016582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401797710","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9809553,0.013168233,0.000116996656,0.0011243459,0.0008986071,0.0010037273,0.0000109589,0.00016465307,0.0025571731],"genre_scores_gemma":[0.99738604,0.00064170524,0.0000181752,0.0005092414,0.0002945512,0.00015216498,0.00002566601,0.00003932836,0.0009331256],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99827623,0.00029382118,0.00035077843,0.0004090799,0.000341168,0.00032894828],"domain_scores_gemma":[0.9987868,0.00059097545,0.00010949409,0.00035723887,0.00006804457,0.00008746361],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006326562,0.00025048293,0.00041406357,0.00020900289,0.00011580937,0.000048093785,0.00012177545,0.00018417319,0.00013958802],"category_scores_gemma":[0.00017723202,0.00014283787,0.0001422233,0.0008496909,0.00041751182,0.00015955449,0.000046841982,0.0005506003,0.000055555072],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.018832548,0.002333008,0.007517909,0.0032486194,0.0059519466,0.0016618434,0.027609179,0.00061446003,0.48619092,0.2910649,0.029633038,0.12534164],"study_design_scores_gemma":[0.018194403,0.0020759848,0.5744014,0.0009634886,0.0013837958,0.00079288724,0.0011775371,0.042218715,0.3176423,0.01507604,0.02528912,0.00078436115],"about_ca_topic_score_codex":0.00010625973,"about_ca_topic_score_gemma":0.000023009787,"teacher_disagreement_score":0.56688344,"about_ca_system_score_codex":0.00008841615,"about_ca_system_score_gemma":0.00024652402,"threshold_uncertainty_score":0.58247596},"labels":[],"label_agreement":null},{"id":"W4401995297","doi":"10.1101/2024.08.23.609447","title":"BCL2L13 Influences Autophagy and Ceramide Metabolism without Affecting Temozolomide Resistance in Glioblastoma","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Health Sciences Centre; St. Boniface Hospital; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"","keywords":"Ceramide; Autophagy; Temozolomide; Apoptosis; Viability assay; Gene knockdown; Cancer research; Flux (metallurgy); Cell biology; Chemistry; Biology; Glioblastoma; Biochemistry","score_opus":0.00941183006684784,"score_gpt":0.250257106872679,"score_spread":0.24084527680583115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401995297","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9514613,0.045198586,0.00002475307,0.00041705716,0.0009743054,0.0011078005,0.00008888994,0.00067115814,0.000056111447],"genre_scores_gemma":[0.9950714,0.0010067837,0.002213432,0.0005230944,0.0006767898,0.00025827333,2.0287837e-7,0.00020402968,0.000045954253],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9962717,0.00019091059,0.0007937816,0.0014674531,0.00053416943,0.0007419555],"domain_scores_gemma":[0.99771065,0.00011823908,0.0003577025,0.0011482936,0.00022898545,0.00043613583],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007695467,0.00079846405,0.0012404297,0.0006873022,0.00013656823,0.00026348545,0.00033525148,0.00066672167,0.00004114964],"category_scores_gemma":[0.00033853878,0.00077422406,0.00021854592,0.0007961649,0.00027251415,0.0001595767,0.00056544394,0.0016333393,0.000066265166],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015838197,0.00053996756,0.052693434,0.00851457,0.0016438996,0.003713295,0.00036095548,0.000062900755,0.92539215,0.0049529593,0.000506412,0.000035635177],"study_design_scores_gemma":[0.0023610964,0.00012036414,0.6576746,0.0047090077,0.0008040005,3.338701e-7,0.000020333406,0.00043212672,0.3292279,0.0002246605,0.003136197,0.0012893651],"about_ca_topic_score_codex":0.000078873076,"about_ca_topic_score_gemma":0.000035983976,"teacher_disagreement_score":0.6049812,"about_ca_system_score_codex":0.0002975225,"about_ca_system_score_gemma":0.0008722568,"threshold_uncertainty_score":0.9994709},"labels":[],"label_agreement":null},{"id":"W4402025728","doi":"10.1016/j.xhgg.2024.100349","title":"Dominantly acting variants in ATP6V1C1 and ATP6V1B2 cause a multisystem phenotypic spectrum by altering lysosomal and/or autophagosome function","year":2024,"lang":"en","type":"article","venue":"Human Genetics and Genomics Advances","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Collège Montmorency","funders":"Ministero dell'Istruzione e del Merito; Fondazione Telethon; National Institute of Neurological Disorders and Stroke; U.S. Department of Health and Human Services; National Institutes of Health; Universitätsklinikum Hamburg-Eppendorf; Health Resources and Services Administration; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Fondazione Bambino Gesù; National Institute of Child Health and Human Development; Ministero dell’Istruzione, dell’Università e della Ricerca; Ministero della Salute","keywords":"Phenotype; Autophagy; Cell biology; Biology; Function (biology); Autophagosome; Genetics; Computational biology; Gene","score_opus":0.01642224199045167,"score_gpt":0.287651379932893,"score_spread":0.27122913794244136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402025728","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9164326,0.082538076,0.00029529302,0.000071168055,0.00021327386,0.0003019561,0.000022871991,0.00004292403,0.00008181029],"genre_scores_gemma":[0.98789257,0.010979552,0.00041795525,0.0000911092,0.00023690751,0.000019167244,0.000012964911,0.000040935032,0.00030886376],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988606,0.000025275733,0.00029441237,0.00045021085,0.000097819924,0.00027169642],"domain_scores_gemma":[0.99957293,0.00006219969,0.00006319132,0.00015115285,0.000011265281,0.00013926107],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000121243465,0.00021127875,0.00029726437,0.00012116405,0.00015858421,0.00011371777,0.000043487882,0.00007671199,0.00002211501],"category_scores_gemma":[0.000007170011,0.0001818899,0.000029466548,0.00008743267,0.00008006676,0.00011752131,0.00006438948,0.0001425484,0.0000027458864],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025717767,0.00042736568,0.07682488,0.0049083773,0.00083788874,0.0017100568,0.009452478,0.0001864091,0.5801533,0.005796433,0.000091202775,0.31703982],"study_design_scores_gemma":[0.018675938,0.0052179922,0.7822705,0.0031476344,0.0013502641,0.0014897537,0.0038250426,0.061999753,0.03616725,0.019938184,0.063191235,0.002726468],"about_ca_topic_score_codex":0.00002399666,"about_ca_topic_score_gemma":0.00009185106,"teacher_disagreement_score":0.7054456,"about_ca_system_score_codex":0.000050483497,"about_ca_system_score_gemma":0.00003849353,"threshold_uncertainty_score":0.7417255},"labels":[],"label_agreement":null},{"id":"W4402201695","doi":"10.1016/j.phrs.2024.107394","title":"Investigating the interplay between mitophagy and diabetic neuropathy: Uncovering the hidden secrets of the disease pathology","year":2024,"lang":"en","type":"review","venue":"Pharmacological Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"National Institute of General Medical Sciences; National Institutes of Health; Ministry of Education, India; National University of Singapore","keywords":"Mitophagy; Disease; Autophagy; Medicine; Insulin resistance; Diabetes mellitus; Oxidative stress; Mitochondrion; Bioinformatics; Neuroscience; Biology; Cell biology; Internal medicine; Endocrinology; Apoptosis; Genetics","score_opus":0.17440622473680853,"score_gpt":0.5022761170722977,"score_spread":0.32786989233548913,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402201695","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10404576,0.8913312,0.0000011166948,0.0018656355,0.00029936308,0.0020610539,0.00009476701,0.00003759438,0.00026350401],"genre_scores_gemma":[0.20968904,0.7882535,0.0000043179234,0.00056220446,0.00071815174,0.000399719,0.000016454918,0.000049634502,0.00030697903],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9942095,0.0031054965,0.0006114314,0.00059133023,0.000869532,0.0006126538],"domain_scores_gemma":[0.99424475,0.004425407,0.00018177478,0.0006260012,0.0001258198,0.00039626524],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0023346157,0.0003683313,0.0009943203,0.0001259874,0.00038708368,0.00008146585,0.0010350533,0.00019482143,0.00017860883],"category_scores_gemma":[0.001856271,0.0001323095,0.000500457,0.0008487801,0.0018238784,0.000034219236,0.0015980683,0.0030256019,0.000056298297],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008233658,0.00016357281,0.0018032838,0.016085863,0.0010548439,0.001133587,0.00051841,8.7872877e-7,0.0004422824,0.00046826262,0.0032757276,0.97497094],"study_design_scores_gemma":[0.0016355992,0.0009975248,0.023641298,0.021411173,0.0136231175,0.0002814441,0.00021659932,0.00032646683,0.0006121429,0.014212467,0.9222367,0.0008054581],"about_ca_topic_score_codex":0.000008517147,"about_ca_topic_score_gemma":4.1069856e-7,"teacher_disagreement_score":0.9741655,"about_ca_system_score_codex":0.00009850242,"about_ca_system_score_gemma":0.00069313485,"threshold_uncertainty_score":0.99927443},"labels":[],"label_agreement":null},{"id":"W4402707052","doi":"10.1038/s41388-024-03170-6","title":"MYC upstream region orchestrates resistance to PI3K inhibitors in cancer cells through FOXO3a-mediated autophagic adaptation","year":2024,"lang":"en","type":"article","venue":"Oncogene","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Associazione Italiana per la Ricerca sul Cancro; Istituto Pasteur-Fondazione Cenci Bolognetti; Sapienza Università di Roma; Ministero dell’Istruzione, dell’Università e della Ricerca","keywords":"Biology; Autophagy; Adaptation (eye); PI3K/AKT/mTOR pathway; Upstream (networking); Carcinogenesis; Cell biology; Cancer research; Cancer; Cancer cell; Downregulation and upregulation; Genetics; Gene; Apoptosis; Signal transduction; Neuroscience","score_opus":0.03732684379423209,"score_gpt":0.32434108770237724,"score_spread":0.2870142439081452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402707052","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97255504,0.018378554,0.00040926182,0.0032290597,0.00067544484,0.0006241176,0.000038393417,0.00024340881,0.003846706],"genre_scores_gemma":[0.99163985,0.001779444,0.00064395904,0.0009602437,0.00039221917,0.00014268128,0.00006247513,0.00004957344,0.004329577],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986388,0.00004945952,0.00031629862,0.00042692723,0.00026667677,0.00030182244],"domain_scores_gemma":[0.99938875,0.00008780838,0.00004972238,0.00026030853,0.00005927927,0.00015413595],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011279615,0.0002046473,0.0002648402,0.00014556985,0.00004193492,0.000033633456,0.00008589818,0.00013005635,0.00016802963],"category_scores_gemma":[0.00002898785,0.00017830372,0.00009145116,0.00075673265,0.0000438766,0.00014527148,0.000017403523,0.00017801988,0.0001994757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020286625,0.0010647186,0.0025542781,0.0010487109,0.00047530996,0.004870978,0.015576784,0.0015068548,0.82104516,0.0019270197,0.053929817,0.09397169],"study_design_scores_gemma":[0.0025091013,0.00053451693,0.0058076163,0.0025043045,0.00020960053,0.000025816815,0.0008568451,0.0022345097,0.85688555,0.0029487123,0.12486377,0.00061966403],"about_ca_topic_score_codex":0.0003091198,"about_ca_topic_score_gemma":0.00035029236,"teacher_disagreement_score":0.09335203,"about_ca_system_score_codex":0.00029893464,"about_ca_system_score_gemma":0.0004132262,"threshold_uncertainty_score":0.72710145},"labels":[],"label_agreement":null},{"id":"W4402709976","doi":"10.1101/2024.09.19.613961","title":"TBC1D24 regulates mitochondria and endoplasmic reticulum-mitochondria contact sites","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université du Québec à Trois-Rivières; Université du Québec; Centre Hospitalier Universitaire Sainte-Justine; Université du Québec à Montréal","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Courtois Foundation","keywords":"Endoplasmic reticulum; Mitochondrion; Cell biology; Chemistry; Biology","score_opus":0.010168759864668465,"score_gpt":0.23285321403228737,"score_spread":0.2226844541676189,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402709976","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96628004,0.02733666,0.00004028052,0.00093492656,0.0024567978,0.0015973124,0.0003415833,0.0009447794,0.0000675877],"genre_scores_gemma":[0.99269885,0.0017604198,0.0025187666,0.0007290858,0.0015261613,0.00031896465,0.0000030435926,0.0003060806,0.0001386512],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9960754,0.0001286236,0.00078068534,0.0016724144,0.00057912414,0.00076377107],"domain_scores_gemma":[0.9966497,0.00014386929,0.00033042935,0.0017886169,0.00037656966,0.00071080925],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002890326,0.0009842479,0.0012161029,0.0004645387,0.00016703155,0.000368803,0.00036029128,0.00092893996,0.00032240828],"category_scores_gemma":[0.0002410251,0.00092479703,0.00039782343,0.00045761463,0.00024310598,0.00014278728,0.0006513632,0.0015468682,0.00033837394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025328828,0.0002010902,0.003282131,0.0019060249,0.001068992,0.00091902097,0.000033275523,0.0000029400433,0.9851955,0.0022588891,0.0048754625,0.000003371946],"study_design_scores_gemma":[0.0024326222,0.00032036478,0.0784746,0.003039214,0.0018682983,0.0000010006927,0.000010379055,0.0007064161,0.9004712,0.00017316021,0.011070495,0.0014322441],"about_ca_topic_score_codex":0.000037200898,"about_ca_topic_score_gemma":0.0000024878043,"teacher_disagreement_score":0.084724315,"about_ca_system_score_codex":0.00022826546,"about_ca_system_score_gemma":0.0008311773,"threshold_uncertainty_score":0.99932027},"labels":[],"label_agreement":null},{"id":"W4402784642","doi":"10.1016/j.celrep.2024.114816","title":"Destruction as a creative process: CAD-induced DNA strand breaks promote macrophage differentiation","year":2024,"lang":"en","type":"letter","venue":"Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Stem Cell Network; University of Ottawa","funders":"","keywords":"Macrophage; Cell biology; DNA; Process (computing); Chemistry; Genetics; Biology; Biochemistry; Computer science","score_opus":0.011107206673199777,"score_gpt":0.2726779627475656,"score_spread":0.26157075607436586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402784642","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9644829,0.0016063348,0.00002567492,0.015832044,0.001969789,0.0016970594,0.00003107756,0.00034359793,0.014011514],"genre_scores_gemma":[0.9308619,0.00009478389,0.000035302564,0.035208464,0.0036006498,0.00020015868,0.0013603985,0.00019097277,0.0284474],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972381,0.000058171758,0.0006690293,0.0009244256,0.00071076414,0.0003994827],"domain_scores_gemma":[0.99842596,0.000023644798,0.0005509153,0.00063256157,0.00020193026,0.00016500705],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001204432,0.000517287,0.00063688343,0.00023422498,0.00010255429,0.00009919546,0.00006315262,0.00095357,0.0011614182],"category_scores_gemma":[0.000052600495,0.0004292216,0.0003092794,0.00019710705,0.000056896068,0.00010662515,0.000024021992,0.0014739688,0.0001110736],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040666817,0.00066191005,0.00043512613,0.011494535,0.0019364506,0.29748958,0.0040910705,0.0000023215348,0.09575609,0.00000888325,0.57735074,0.010366617],"study_design_scores_gemma":[0.0024974986,0.0013647163,0.0059863185,0.003351565,0.0054605305,0.017608937,0.00018703299,0.00008205344,0.7917933,0.026965514,0.14295286,0.0017496599],"about_ca_topic_score_codex":0.00007227034,"about_ca_topic_score_gemma":0.0000013661966,"teacher_disagreement_score":0.69603723,"about_ca_system_score_codex":0.00018537785,"about_ca_system_score_gemma":0.00056697335,"threshold_uncertainty_score":0.99981594},"labels":[],"label_agreement":null},{"id":"W4402851579","doi":"10.1016/j.freeradbiomed.2024.09.028","title":"Regulation of lysosomes in skeletal muscle during exercise, disuse and aging","year":2024,"lang":"en","type":"review","venue":"Free Radical Biology and Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Lysosome; Skeletal muscle; Mitochondrion; Sarcopenia; Cell biology; Chemistry; Medicine; Endocrinology; Biology; Biochemistry","score_opus":0.021829963360413717,"score_gpt":0.3503856183669388,"score_spread":0.3285556550065251,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402851579","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.01360322,0.98508143,0.0000041149547,0.0005174956,0.00018196789,0.00042104928,0.000022540313,0.0000308088,0.00013739592],"genre_scores_gemma":[0.015908599,0.98315245,0.000032972428,0.000044254586,0.00039113022,0.000029012252,0.00015490656,0.000022817032,0.00026387145],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987349,0.00007620076,0.00052471954,0.0003676333,0.00009732974,0.00019921684],"domain_scores_gemma":[0.9993021,0.0001395361,0.00011672848,0.00026278498,0.000013430101,0.00016545088],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022974431,0.00025394105,0.0015638701,0.00034484648,0.00003212551,0.0000020730859,0.00007846972,0.0003685187,0.00010179167],"category_scores_gemma":[0.00014474076,0.00015334917,0.00011094532,0.00022813492,0.000823406,0.000024492334,0.00007955097,0.0003865665,0.0000030471394],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032573676,0.000060224538,0.00029588575,0.024406036,0.00020571116,0.00014426699,0.0001675847,9.5201225e-9,0.00017763146,0.0015045922,0.0002783806,0.9727271],"study_design_scores_gemma":[0.005692953,0.0006227852,0.0340187,0.118048646,0.0059298486,0.000498333,0.00008019198,0.000020993963,0.000037487825,0.007938844,0.8266226,0.0004885921],"about_ca_topic_score_codex":0.000025085666,"about_ca_topic_score_gemma":0.0000034610955,"teacher_disagreement_score":0.97223854,"about_ca_system_score_codex":0.000026461978,"about_ca_system_score_gemma":0.00007236605,"threshold_uncertainty_score":0.6253398},"labels":[],"label_agreement":null},{"id":"W4402926981","doi":"10.1007/7651_2024_571","title":"Assessing Autophagy Flux in Glioblastoma Temozolomide Resistant Cells","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"","keywords":"Temozolomide; Autophagy; Glioblastoma; Flux (metallurgy); Cancer research; Medicine; Chemistry; Apoptosis; Biochemistry","score_opus":0.023910433302076033,"score_gpt":0.4337185282828551,"score_spread":0.4098080949807791,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402926981","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.62644035,0.011991351,0.35718742,0.00041857595,0.0006993693,0.00037034115,0.0000055794544,0.00015240921,0.0027346204],"genre_scores_gemma":[0.429259,0.000106457905,0.5685681,0.001304993,0.00010882051,0.000070929505,0.000015513178,0.00006499526,0.00050117366],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973961,0.0010898516,0.00045477055,0.00054007996,0.000096117416,0.00042308206],"domain_scores_gemma":[0.99910635,0.00034752022,0.000044169254,0.00038194936,0.00002376781,0.00009627275],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013895611,0.00021468662,0.00047930278,0.0005305868,0.000024489496,0.000038164988,0.0001414375,0.00028964816,0.00022381941],"category_scores_gemma":[0.00021647612,0.0001854778,0.00015016463,0.0006662661,0.00013535288,0.000055150707,0.00006856968,0.0004419387,0.0000379919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015989103,0.00008616376,0.00018910931,0.00009218733,0.00005635714,0.0030214512,0.0001123753,0.000015351865,0.95138097,0.003433436,0.000048986694,0.041403748],"study_design_scores_gemma":[0.0008226806,0.00031227578,0.0017872714,0.00023906259,0.00004212975,0.000059064154,0.00008087264,0.0019386511,0.97377086,0.014208053,0.0065451926,0.00019388268],"about_ca_topic_score_codex":0.000037502145,"about_ca_topic_score_gemma":0.000008429929,"teacher_disagreement_score":0.21138068,"about_ca_system_score_codex":0.0001512476,"about_ca_system_score_gemma":0.00020884526,"threshold_uncertainty_score":0.7563565},"labels":[],"label_agreement":null},{"id":"W4402961561","doi":"10.1080/15548627.2024.2405956","title":"Epg5 links proteotoxic stress due to defective autophagic clearance and epileptogenesis in <i>Drosophila</i> and Vici syndrome patients","year":2024,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Thomas Hospital","funders":"Universität zu Köln; National Centre for the Replacement, Refinement and Reduction of Animals in Research; European Commission; Horizon 2020 Framework Programme; Deutsche Forschungsgemeinschaft; Action Medical Research","keywords":"Autophagy; Biology; Epileptogenesis; TFEB; Neuroscience; Cell biology; Neurodegeneration; Epilepsy; Genetics; Pathology; Medicine; Disease","score_opus":0.0064654027582203115,"score_gpt":0.252079715515814,"score_spread":0.24561431275759368,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402961561","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9880649,0.009021553,0.000052489515,0.00038966228,0.000252856,0.0015738346,0.000086964676,0.00020509434,0.0003526388],"genre_scores_gemma":[0.9974125,0.0003315039,0.00021472802,0.00129978,0.00009735105,0.00026058662,0.000025679503,0.00007261759,0.00028525814],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99805444,0.00008166295,0.00036943605,0.0007510712,0.00029649865,0.0004468599],"domain_scores_gemma":[0.99911624,0.00010732294,0.000048110207,0.00032491758,0.00005913713,0.00034425312],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017039699,0.0003330181,0.00053683686,0.00030879347,0.0000904405,0.00007246016,0.000103982435,0.00026689097,0.00009656017],"category_scores_gemma":[0.00006046547,0.00030191787,0.00009047892,0.0005341243,0.00011638942,0.00019065198,0.000105678824,0.00042790078,0.00011800809],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005883613,0.00579672,0.29253885,0.008471956,0.002391518,0.038665604,0.016137602,0.0002444401,0.04133631,0.007424777,0.0013716156,0.579737],"study_design_scores_gemma":[0.0020818284,0.0011655533,0.97653073,0.00091201375,0.00010497756,0.0003068779,0.000033617933,0.00075774296,0.0153754875,0.0015502593,0.0008052479,0.00037567556],"about_ca_topic_score_codex":0.000066690205,"about_ca_topic_score_gemma":0.000013837486,"teacher_disagreement_score":0.68399185,"about_ca_system_score_codex":0.00010365181,"about_ca_system_score_gemma":0.000100139005,"threshold_uncertainty_score":0.9999433},"labels":[],"label_agreement":null},{"id":"W4403146612","doi":"","title":"Functions in T cells of Lis1 protein, a regulator of dynein-dependent microtubules dynamics","year":2018,"lang":"fr","type":"preprint","venue":"theses.fr (ABES)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"U.S. National Library of Medicine; National Institute of Child Health and Human Development; Conseil Régional Midi-Pyrénées; University of California, San Francisco; Ministère de l'Education Nationale, de l'Enseignement Superieur et de la Recherche; Institut National de la Santé et de la Recherche Médicale; McGill University; Agence Nationale de la Recherche; National Institutes of Health; Fondation pour l'Aide à la Recherche sur la Sclérose en Plaques; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Sanofi","keywords":"Dynein; Microtubule; Regulator; Cell biology; Dynamics (music); Chemistry; Biophysics; Biology; Physics; Biochemistry","score_opus":0.012798010514497206,"score_gpt":0.25971248522866314,"score_spread":0.24691447471416594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403146612","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9729369,0.005970626,0.0006866003,0.00031827297,0.001630583,0.00293966,0.0013732896,0.00007015542,0.014073866],"genre_scores_gemma":[0.9919587,0.0010607933,0.0007487102,0.000082743594,0.0008333222,0.00025652847,0.00026070158,0.00014767407,0.0046508275],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.995425,0.00039474465,0.0016403133,0.00092355255,0.00080776203,0.0008086395],"domain_scores_gemma":[0.9958252,0.00023101972,0.0010560227,0.0020172093,0.0005319579,0.00033862158],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009086608,0.0007699902,0.0017013568,0.0005026008,0.00008595888,0.00002484731,0.00077548716,0.0009143699,0.003612086],"category_scores_gemma":[0.00017075561,0.000732548,0.0005595671,0.000440206,0.0010612421,0.00011143435,0.00056205323,0.0009485096,0.00045111022],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0044278614,0.011490672,0.0116245225,0.011557763,0.00436403,0.0004075811,0.013751247,0.00075455214,0.78939617,0.13511401,0.00059723767,0.016514333],"study_design_scores_gemma":[0.0045988183,0.0012980326,0.015400284,0.011795603,0.0012219157,0.000041672443,0.006223644,0.0015927017,0.94014925,0.011473263,0.005118717,0.0010860933],"about_ca_topic_score_codex":0.005639226,"about_ca_topic_score_gemma":0.00067281333,"teacher_disagreement_score":0.15075308,"about_ca_system_score_codex":0.0006115277,"about_ca_system_score_gemma":0.00086575735,"threshold_uncertainty_score":0.99951255},"labels":[],"label_agreement":null},{"id":"W4403227595","doi":"10.1016/j.cjca.2024.08.011","title":"NOVEL ROLE OF RAB8B IN REGULATING AUTOPHAGY AGAINST MYOCARDIAL ISCHEMIA-REPERFUSION INJURY","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Autophagy; Reperfusion injury; Myocardial ischemia; Ischemia; Cardiology; Myocardial Reperfusion Injury; Internal medicine; Pharmacology; Apoptosis; Biochemistry","score_opus":0.008656987267628164,"score_gpt":0.2524570437711037,"score_spread":0.2438000565034755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403227595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98288864,0.008294467,0.00021866293,0.00035512925,0.0007438552,0.0000983176,0.000027162238,0.0000085816955,0.0073651904],"genre_scores_gemma":[0.9979951,0.0001586466,0.00019284053,0.00024307102,0.0013073767,0.0000020692755,0.000008353065,0.00002289528,0.000069647554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988629,0.00006250646,0.0005015748,0.00014809637,0.00014018104,0.00028473226],"domain_scores_gemma":[0.999127,0.000067480265,0.000111160516,0.00018048762,0.00012598274,0.00038791483],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004503466,0.0001270578,0.00058633735,0.0005146452,0.000031611184,0.000010351145,0.00011461619,0.0001909372,0.000034968798],"category_scores_gemma":[0.00015180766,0.00011136706,0.00032958068,0.0002371714,0.00012741332,0.00007711298,0.00001223141,0.00039534617,0.000004989213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030002816,0.000010463591,0.01250572,0.00009431291,0.000608193,0.0012445379,0.0007574444,0.0015575655,0.89655715,0.0008548838,0.0035286092,0.08198109],"study_design_scores_gemma":[0.00808774,0.0020669925,0.1342499,0.0031343687,0.00088773045,0.0054941014,0.001597918,0.0028041522,0.54330045,0.003361725,0.29411623,0.0008986765],"about_ca_topic_score_codex":0.00032415453,"about_ca_topic_score_gemma":0.00008192663,"teacher_disagreement_score":0.35325667,"about_ca_system_score_codex":0.00019299737,"about_ca_system_score_gemma":0.002119072,"threshold_uncertainty_score":0.45414168},"labels":[],"label_agreement":null},{"id":"W4403418147","doi":"10.21203/rs.3.rs-5153449/v1","title":"ULK1 is required for autophagy and promotes metastatic progression in epithelial ovarian cancer","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Autophagy; Ovarian cancer; Cancer research; Epithelial ovarian cancer; ULK1; Metastasis; Cancer; Oncology; Medicine; Internal medicine; Biology; Cell biology; Apoptosis; Kinase; Biochemistry; AMPK; Protein kinase A","score_opus":0.09707559661517587,"score_gpt":0.48478426013308223,"score_spread":0.38770866351790634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403418147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92484355,0.052169535,0.00005872422,0.011151091,0.00045675412,0.009275988,0.0013412689,0.00017470661,0.00052840717],"genre_scores_gemma":[0.9872434,0.0026447475,0.0015022411,0.00015878998,0.00066085346,0.0048099337,0.00022909674,0.00012394745,0.0026269627],"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.99679095,0.00026406848,0.00042342278,0.00090965093,0.0009070996,0.00070478854],"domain_scores_gemma":[0.99840367,0.00026704752,0.00007776497,0.0005814779,0.00035786798,0.00031217103],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001464647,0.00031538616,0.00063673785,0.0006389444,0.00012280926,0.00014103086,0.00020025407,0.0003069328,0.0003975548],"category_scores_gemma":[0.0003277935,0.00024103241,0.00019828031,0.0003929371,0.00021881443,0.000051007875,0.00063442753,0.0013109889,0.000031558862],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010601208,0.0034463855,0.005754404,0.12331455,0.0034634585,0.004810406,0.023673514,0.000027023578,0.03899998,0.007953576,0.017338729,0.7606168],"study_design_scores_gemma":[0.021454195,0.006202754,0.05920988,0.08034628,0.0014019056,0.000118391996,0.0018875115,0.04640374,0.22650382,0.52358395,0.030675486,0.0022120916],"about_ca_topic_score_codex":0.00039065065,"about_ca_topic_score_gemma":0.000048649505,"teacher_disagreement_score":0.7584047,"about_ca_system_score_codex":0.00029305473,"about_ca_system_score_gemma":0.0016294448,"threshold_uncertainty_score":0.98290163},"labels":[],"label_agreement":null},{"id":"W4403513715","doi":"10.1186/s40478-024-01872-2","title":"Acquisition of neurodegenerative features in isogenic OPTN(E50K) human stem cell-derived retinal ganglion cells associated with autophagy disruption and mTORC1 signaling reduction","year":2024,"lang":"en","type":"article","venue":"Acta Neuropathologica Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Eye Institute; National Center for Advancing Translational Sciences; Fonds de Recherche du Québec - Santé; Glaucoma Research Foundation; Canadian Institutes of Health Research; Indiana State Department of Health; BrightFocus Foundation; Gilbert Family Foundation","keywords":"mTORC1; Autophagy; Cell biology; Neuroscience; Stem cell; Biology; Retinal ganglion cell; Retinal; Signal transduction; Retina; PI3K/AKT/mTOR pathway","score_opus":0.023741080839824784,"score_gpt":0.2855355603980641,"score_spread":0.2617944795582393,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403513715","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99652815,0.0017321083,0.000096180396,0.0005141771,0.00006358303,0.0004913175,0.000028656485,0.00013620403,0.00040965437],"genre_scores_gemma":[0.99813175,0.00096483756,0.00030034225,0.000095489704,0.000043100583,0.00006497845,0.00019742212,0.000033199496,0.000168878],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99835926,0.00056887267,0.0003485288,0.00036465694,0.00017819763,0.00018047584],"domain_scores_gemma":[0.9987887,0.00016521088,0.0001804145,0.0006806927,0.00011500807,0.00006997422],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000280896,0.0001969085,0.00028454265,0.00021448983,0.00024270835,0.0000475635,0.00020597463,0.0001187474,0.000021395406],"category_scores_gemma":[0.000018684143,0.00016228278,0.00007642281,0.0004719517,0.00025182025,0.0001719245,0.000108137174,0.00044578456,0.0000023605448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000117543634,0.0003539456,0.00029124573,0.000046924113,0.000026633486,0.000103441926,0.0016684372,0.0000677066,0.9965607,0.00024943484,0.00004031785,0.00047366967],"study_design_scores_gemma":[0.001468316,0.0017926805,0.21067628,0.0006327001,0.0003585299,0.00026547507,0.0009602243,0.0020875887,0.7811235,0.00027143405,0.000044137345,0.0003191347],"about_ca_topic_score_codex":0.000010326007,"about_ca_topic_score_gemma":0.0000039234205,"teacher_disagreement_score":0.2154372,"about_ca_system_score_codex":0.0000659461,"about_ca_system_score_gemma":0.00005533979,"threshold_uncertainty_score":0.66177},"labels":[],"label_agreement":null},{"id":"W4403758756","doi":"10.1101/2024.10.23.619899","title":"Unc-51-like Kinase 1 (ULK1) Regulates Bacterial Ubiquitylation and p62 Recruitment during Xenophagic Clearance of <i>Listeria monocyt</i> ogenes","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Listeria monocytogenes; ULK1; Cell biology; Listeria; Kinase; Chemistry; Ubiquitin; Microbiology; Protein kinase A; Biology; Bacteria; Biochemistry; Genetics; AMPK","score_opus":0.02592275841397224,"score_gpt":0.2599569293788658,"score_spread":0.23403417096489354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403758756","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98208827,0.0136511745,0.000016858445,0.00018241965,0.0018112734,0.0015961375,0.00029704484,0.00034558418,0.000011228271],"genre_scores_gemma":[0.99578184,0.0016368368,0.0010730396,0.00013346103,0.000870155,0.00028307815,0.000003249062,0.00017895152,0.00003941914],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99707305,0.00012115511,0.0007908642,0.0011150567,0.0004294041,0.0004704421],"domain_scores_gemma":[0.99764913,0.000037787806,0.00046097924,0.001214778,0.000301734,0.000335603],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036725795,0.0006536874,0.0009400683,0.00031367425,0.00012613037,0.00015340501,0.00024530906,0.00053935946,0.00011794252],"category_scores_gemma":[0.000046389945,0.0006582675,0.0002307113,0.00035352062,0.0001999594,0.00012093555,0.0005875894,0.00051448157,0.000034610435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009748426,0.00023078539,0.0012406326,0.003703033,0.0005131382,0.0002524058,0.00004979439,0.000021307202,0.9927103,0.00021751926,0.000064479784,0.000021769782],"study_design_scores_gemma":[0.0016260917,0.00017066521,0.17363736,0.0019276316,0.00060639414,2.842175e-7,0.0000047165004,0.00018340553,0.8200506,0.000036276702,0.0011934859,0.00056309375],"about_ca_topic_score_codex":0.000036139114,"about_ca_topic_score_gemma":0.0000014921752,"teacher_disagreement_score":0.1726597,"about_ca_system_score_codex":0.00027912753,"about_ca_system_score_gemma":0.00045494182,"threshold_uncertainty_score":0.9995869},"labels":[],"label_agreement":null},{"id":"W4403808959","doi":"10.1016/j.bbamcr.2024.119869","title":"Endoplasmic reticulum stress induced autophagy in cancer and its potential interactions with apoptosis and ferroptosis","year":2024,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"CSIR-Indian Institute of Toxicology Research, Government of India","keywords":"Endoplasmic reticulum; Autophagy; Apoptosis; Cell biology; Unfolded protein response; Cancer research; Chemistry; Biology; Genetics","score_opus":0.07033932367190066,"score_gpt":0.41760868574768206,"score_spread":0.3472693620757814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403808959","genre_codex":"empirical","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.52764153,0.46999618,0.000001000541,0.00042182778,0.000099260404,0.0013338762,0.00016148445,0.00004885803,0.00029597667],"genre_scores_gemma":[0.4203962,0.5782683,0.000031075182,0.00005296638,0.00011343406,0.0004732357,0.00014848057,0.00013822885,0.0003781042],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9955116,0.00060078275,0.00061337557,0.0014293202,0.00097327057,0.0008716652],"domain_scores_gemma":[0.9981944,0.000175511,0.00019355219,0.00071376003,0.00021958516,0.0005031849],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003238126,0.00079138635,0.0015678663,0.0012079052,0.00016797867,0.0002607826,0.00036172083,0.00045724472,0.000064854845],"category_scores_gemma":[0.000042316562,0.0005977747,0.0003770081,0.001404996,0.00029325116,0.00013386637,0.0004797112,0.00238151,0.00005107392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006877042,0.0019334842,0.0000011331497,0.045674212,0.0030371877,0.0015603813,0.0007992147,0.0000013093519,0.87550426,0.00027165483,0.0005132128,0.070016265],"study_design_scores_gemma":[0.0017396146,0.0010400426,0.000043582208,0.023341855,0.0035118288,0.00011253008,0.00018919479,0.00027255798,0.9557977,0.000053303007,0.012872291,0.0010255328],"about_ca_topic_score_codex":0.00020053786,"about_ca_topic_score_gemma":0.000014623274,"teacher_disagreement_score":0.10827208,"about_ca_system_score_codex":0.00024936238,"about_ca_system_score_gemma":0.0011827425,"threshold_uncertainty_score":0.99992},"labels":[],"label_agreement":null},{"id":"W4403933634","doi":"10.1101/2024.10.30.621097","title":"Sex and Region-Specific Disruption of Autophagy and Mitophagy in Alzheimer’s Disease: Linking Cellular Dysfunction to Cognitive Decline","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Mitophagy; Autophagy; Disease; Cognitive decline; Neuroscience; Cognition; Medicine; Gerontology; Psychology; Biology; Internal medicine; Dementia; Genetics","score_opus":0.02154853286936781,"score_gpt":0.2592628341119965,"score_spread":0.2377143012426287,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403933634","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9337991,0.06261072,0.0010427533,0.00030256296,0.0006522685,0.0012699442,0.00013398922,0.00018259608,0.0000060759717],"genre_scores_gemma":[0.9951454,0.0031105035,0.00047020876,0.00033892205,0.0005988427,0.00019675543,0.0000034743987,0.00012842838,0.000007484461],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99733543,0.00012066324,0.0006552546,0.0011216135,0.00039362823,0.00037343366],"domain_scores_gemma":[0.9982769,0.00010717283,0.00024425858,0.0006170149,0.00027060977,0.00048404434],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039403592,0.00051697926,0.00078209734,0.00059912936,0.00007343001,0.00009679712,0.0001241335,0.00040455215,0.000019976767],"category_scores_gemma":[0.000085827814,0.0005343352,0.00013612314,0.00049980823,0.00017234833,0.00008461778,0.0005085881,0.0006837471,0.000018188935],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030932361,0.0012270935,0.11524407,0.0058597233,0.0017502323,0.0040537105,0.00035286497,0.00005017016,0.86479545,0.0023739303,0.00018603654,0.0010134795],"study_design_scores_gemma":[0.0023886145,0.00026552752,0.7126577,0.0051910644,0.0011621678,2.745828e-7,0.000024647057,0.0010486423,0.27522534,0.0001235052,0.0010751914,0.0008373145],"about_ca_topic_score_codex":0.00002596122,"about_ca_topic_score_gemma":0.0000013896306,"teacher_disagreement_score":0.59741366,"about_ca_system_score_codex":0.00012501112,"about_ca_system_score_gemma":0.000339001,"threshold_uncertainty_score":0.9997108},"labels":[],"label_agreement":null},{"id":"W4404172139","doi":"10.1101/2024.11.07.622273","title":"Amyloid signaling in antiphage defense","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Nautical Research Society","funders":"","keywords":"Amyloid (mycology); Medicine; Pathology","score_opus":0.014159439898458102,"score_gpt":0.24679182288407112,"score_spread":0.232632382985613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404172139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9829866,0.013637824,0.00008532104,0.0002881346,0.0012228362,0.0009046303,0.00014454019,0.0006538307,0.0000762627],"genre_scores_gemma":[0.9960018,0.0006287785,0.001364558,0.0007330919,0.0008369495,0.00017564962,6.817527e-7,0.00023403457,0.00002444776],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99693793,0.0001028993,0.000678009,0.0011474617,0.0004781215,0.00065557694],"domain_scores_gemma":[0.9978646,0.00006304254,0.00019963967,0.001274739,0.00020694123,0.00039101182],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005579148,0.00064013246,0.00086593325,0.0006171666,0.000068779635,0.00015165692,0.00031985735,0.0006668588,0.00022527314],"category_scores_gemma":[0.00012299573,0.00064691604,0.00034404107,0.00069581793,0.0001124306,0.0000664561,0.00045727752,0.0016259252,0.0004583376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021846575,0.00044724063,0.009176022,0.002378278,0.0005230937,0.00480175,0.000036267214,0.00006673745,0.98065025,0.001184167,0.00051143655,0.000006274526],"study_design_scores_gemma":[0.0025599964,0.00017013552,0.104005545,0.004856322,0.00088266656,1.8337039e-7,0.000009995604,0.0010024998,0.8803321,0.00009375111,0.0045107473,0.001576058],"about_ca_topic_score_codex":0.000040463576,"about_ca_topic_score_gemma":0.0000011169143,"teacher_disagreement_score":0.10031816,"about_ca_system_score_codex":0.00035251075,"about_ca_system_score_gemma":0.0010302096,"threshold_uncertainty_score":0.9995982},"labels":[],"label_agreement":null},{"id":"W4404527408","doi":"10.3390/biomedicines12112645","title":"Advancements in Autophagy Modulation for the Management of Oral Disease: A Focus on Drug Targets and Therapeutics","year":2024,"lang":"en","type":"review","venue":"Biomedicines","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Research Foundation of Korea; Ministry of Science and ICT, South Korea; Korea Health Industry Development Institute; National Research Foundation","keywords":"Autophagy; Periodontitis; Context (archaeology); Medicine; Cancer; Disease; Bioinformatics; Biology; Pathology; Dentistry; Internal medicine","score_opus":0.0518454596122296,"score_gpt":0.3938560379242952,"score_spread":0.3420105783120656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404527408","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00008736643,0.9958943,0.00013216394,0.00063889276,0.00046857607,0.0025935639,0.00009650764,0.000030114748,0.000058499492],"genre_scores_gemma":[0.0024767662,0.9953723,0.00015671548,0.0001652569,0.00018075897,0.000487623,0.00016374352,0.000050800296,0.00094605697],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99868786,0.000031787367,0.00047010786,0.000334831,0.00028461116,0.0001908007],"domain_scores_gemma":[0.9992845,0.00009862517,0.00015570101,0.00034838758,0.000031451833,0.00008134395],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019873132,0.00030898582,0.000817119,0.00027500978,0.000035506866,0.00000864819,0.00011450339,0.00007442636,0.000016320433],"category_scores_gemma":[0.0000053185363,0.00015996487,0.00020889983,0.00034159626,0.000112975256,0.000024176128,0.000040700546,0.00011399368,0.0000055557616],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015457846,0.00014856328,0.000009207548,0.027121305,0.0010211963,0.000052885578,0.00006770814,5.027903e-7,0.0000012835761,0.00079425075,0.0004001127,0.97022843],"study_design_scores_gemma":[0.0014758981,0.0002008002,0.00084191427,0.024469063,0.0059890654,0.0000036126585,0.000046508743,0.0003844816,0.000004905508,0.0019091617,0.96450835,0.00016621259],"about_ca_topic_score_codex":0.000006535466,"about_ca_topic_score_gemma":0.0000010421126,"teacher_disagreement_score":0.9700622,"about_ca_system_score_codex":0.00006531485,"about_ca_system_score_gemma":0.00007599514,"threshold_uncertainty_score":0.65231776},"labels":[],"label_agreement":null},{"id":"W4404730089","doi":"10.1002/1878-0261.13770","title":"Loss of <i>SETD2</i> in wild‐type <i>VHL</i> clear cell renal cell carcinoma sensitizes cells to <scp>STF</scp> ‐62247 and leads to <scp>DNA</scp> damage, cell cycle arrest, and cell death characteristic of pyroptosis","year":2024,"lang":"en","type":"article","venue":"Molecular Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Atlantic Cancer Research Institute; Université de Moncton","funders":"Canadian Cancer Society Research Institute; New Brunswick Innovation Foundation; Fondation de la recherche en santé du Nouveau-Brunswick; Cancer Research Institute","keywords":"Clear cell renal cell carcinoma; Cell cycle; Biology; Cancer research; Cell cycle checkpoint; Chromatin; DNA repair; Histone; DNA damage; Molecular biology; Cell; Gene; Genetics; DNA; Renal cell carcinoma; Medicine","score_opus":0.00719953472919734,"score_gpt":0.25200315966665304,"score_spread":0.2448036249374557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404730089","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883652,0.0033705775,0.00017940195,0.00019204823,0.0003780339,0.00091763935,0.00014323877,0.000066872206,0.006387031],"genre_scores_gemma":[0.9948239,0.0005433525,0.0011049334,0.0019496379,0.00013490625,0.000033613855,0.00006184253,0.00013363516,0.0012141916],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99679345,0.00030062484,0.00078566046,0.0009386066,0.0004048579,0.0007768103],"domain_scores_gemma":[0.997754,0.0005533556,0.00022484199,0.00065183995,0.00017713378,0.00063886575],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037912163,0.0005271739,0.0011420224,0.000492215,0.00006687267,0.000039924733,0.0002475956,0.00041070615,0.000019625038],"category_scores_gemma":[0.000072098264,0.0005321034,0.00018575374,0.00066496234,0.0002471138,0.00008163535,0.00027563085,0.0004970213,0.00008439779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021753417,0.0007349966,0.0041785394,0.0011997265,0.00005272818,0.003450118,0.0024385573,0.000117136355,0.9838979,0.000027772203,0.0033891718,0.0002957941],"study_design_scores_gemma":[0.0024870778,0.0033701025,0.012849516,0.00018349434,0.00040496225,0.00006339199,0.00044787224,0.00030853617,0.969575,0.00007620056,0.010075213,0.00015865325],"about_ca_topic_score_codex":0.00014594883,"about_ca_topic_score_gemma":0.000015748585,"teacher_disagreement_score":0.014322946,"about_ca_system_score_codex":0.00012780096,"about_ca_system_score_gemma":0.00039082186,"threshold_uncertainty_score":0.99971306},"labels":[],"label_agreement":null},{"id":"W4404756558","doi":"10.1152/ajpregu.00178.2024","title":"The effect of high-intensity exercise in temperate and hot ambient conditions on autophagy and the cellular stress response in young and older females","year":2024,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Internal medicine; Medicine; Endocrinology; Physiological stress; Physiology; Chemistry; Biochemistry; Apoptosis","score_opus":0.010288192707661193,"score_gpt":0.29131575351976385,"score_spread":0.2810275608121027,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404756558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99279237,0.006210963,0.0000052911487,0.00043124612,0.00011465192,0.0004086185,0.000023488858,0.0000062375316,0.0000071079853],"genre_scores_gemma":[0.9985768,0.0011856428,0.000011299903,0.00010466425,0.000046847646,0.00003757897,0.000006013974,0.000010098343,0.000021055377],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9976038,0.001312518,0.00043870532,0.00031908375,0.00011484343,0.00021107012],"domain_scores_gemma":[0.9976515,0.0016744672,0.0002772726,0.00018196386,0.00012239479,0.00009235551],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.00053287024,0.00028333024,0.0012283876,0.00019333253,0.00013829063,0.000019964325,0.000092078444,0.000059654354,0.000008220887],"category_scores_gemma":[0.00005382569,0.0001344703,0.00010158671,0.00020982219,0.004365013,0.000079643134,0.000054289496,0.0004985299,7.0339604e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.056220867,0.00018431092,0.0059977183,0.00010300165,0.0006410227,0.00004083797,0.009746504,0.0000953158,0.9205858,0.0053742523,0.00009466049,0.00091570197],"study_design_scores_gemma":[0.0027844403,0.004467243,0.8797287,0.0007230128,0.000116300645,0.000047796173,0.00614966,0.0005828435,0.10343974,0.0018401685,0.000006291343,0.00011383215],"about_ca_topic_score_codex":0.00016210743,"about_ca_topic_score_gemma":0.000030215893,"teacher_disagreement_score":0.87373096,"about_ca_system_score_codex":0.0000355356,"about_ca_system_score_gemma":0.00007076385,"threshold_uncertainty_score":0.99834454},"labels":[],"label_agreement":null},{"id":"W4404767407","doi":"10.26907/2542-064x.2024.4.658-682","title":"Autophagy in Mononuclear Cells from Patients with Autoimmune Thyroiditis","year":2024,"lang":"en","type":"article","venue":"Učënye zapiski Kazanskogo universiteta. Seriâ  Estestvennye nauki/Učënye zapiski Kazanskogo universiteta. Seriâ Estestvennye nauki/Učenye zapiski Kazanskogo gosudarstvennogo universiteta. Seriâ Estestvennye nauki","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McMaster University","keywords":"Autophagy; Peripheral blood mononuclear cell; Autoimmune thyroiditis; Thyroiditis; Medicine; Immunology; Autoimmunity; Biology; Internal medicine; Thyroid; Antibody; Apoptosis; In vitro; Biochemistry","score_opus":0.003304881559541386,"score_gpt":0.18569125121152422,"score_spread":0.18238636965198282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404767407","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92009014,0.021862527,0.0013344992,0.0027661182,0.0074055362,0.01304513,0.0089133885,0.008046328,0.016536342],"genre_scores_gemma":[0.9306787,0.011986063,0.009533431,0.0028464028,0.0024285454,0.00026043237,0.011643894,0.0037256517,0.026896877],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.95453644,0.0034543585,0.0076138675,0.013716531,0.008748732,0.011930092],"domain_scores_gemma":[0.96732765,0.004660076,0.0045923535,0.0111252675,0.0042162063,0.008078435],"candidate_categories":["metaepi_narrow","bibliometrics","sts","scholarly_communication","open_science","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","sts","scholarly_communication","research_integrity","insufficient_payload"],"category_scores_codex":[0.0032386526,0.011485267,0.01142057,0.012628756,0.0051585156,0.0029243096,0.010208556,0.0066702976,0.0074519548],"category_scores_gemma":[0.000663831,0.012743631,0.0062313615,0.020273352,0.0055362605,0.015080397,0.004541858,0.011518318,0.00541974],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":true,"study_design_scores_codex":[0.070060335,0.051369555,0.23159693,0.01620996,0.049218632,0.21177214,0.059804365,0.043945137,0.10459221,0.02849176,0.049756773,0.08318219],"study_design_scores_gemma":[0.12216479,0.025199246,0.28868338,0.023744604,0.025612565,0.004323022,0.033681307,0.017337956,0.020710994,0.0047445823,0.39628908,0.037508443],"about_ca_topic_score_codex":0.0053569553,"about_ca_topic_score_gemma":0.0024447518,"teacher_disagreement_score":0.34653232,"about_ca_system_score_codex":0.011486453,"about_ca_system_score_gemma":0.007894148,"threshold_uncertainty_score":0.9986952},"labels":[],"label_agreement":null},{"id":"W4405374407","doi":"10.1042/bsr20240137","title":"Recycle, repair, recover: the role of autophagy in modulating skeletal muscle repair and post-exercise recovery","year":2024,"lang":"en","type":"review","venue":"Bioscience Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Academy of Medical Sciences","keywords":"Skeletal muscle; Cell biology; Autophagy; Biology; Context (archaeology); Organelle; Apoptosis; Anatomy; Biochemistry","score_opus":0.016852102747801415,"score_gpt":0.30858166301206336,"score_spread":0.29172956026426194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405374407","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016849995,0.97961444,0.0000010195592,0.00002980782,0.00068421115,0.0013475284,0.000027636393,0.00023029634,0.0012150591],"genre_scores_gemma":[0.0055326493,0.9926664,0.00044919353,0.00006498399,0.00014201527,0.00011027226,0.000031015363,0.000061593666,0.0009418423],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963768,0.00012383243,0.0014331163,0.0010742383,0.0005800466,0.000411933],"domain_scores_gemma":[0.9976023,0.00013851185,0.00078379014,0.0012045018,0.0000916749,0.00017922038],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001585664,0.00043891842,0.00148174,0.0003923412,0.0001088813,0.00004114638,0.00017191406,0.00032608994,0.000041406172],"category_scores_gemma":[0.00058503257,0.00027394723,0.0010208313,0.0010618723,0.0003086359,0.00019132257,0.00021457227,0.00046858858,0.000010195305],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011170275,0.00012011754,0.00012915792,0.0055772285,0.00009291941,0.0015427995,0.00011218364,7.8866856e-7,0.00012872886,0.000053051503,0.00012882796,0.99210304],"study_design_scores_gemma":[0.00022355469,0.0005036907,0.0070094713,0.048516862,0.0025494876,0.004382555,0.00020535836,0.0005761373,0.000098480195,0.0018886243,0.93327194,0.0007738323],"about_ca_topic_score_codex":0.00022755368,"about_ca_topic_score_gemma":0.000009139185,"teacher_disagreement_score":0.9913292,"about_ca_system_score_codex":0.00016671029,"about_ca_system_score_gemma":0.0010749637,"threshold_uncertainty_score":0.9999713},"labels":[],"label_agreement":null},{"id":"W4405889522","doi":"10.1080/15548627.2024.2447213","title":"Structure of the human autophagy factor EPG5 and the molecular basis of its conserved mode of interaction with Atg8-family proteins","year":2024,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Institute of General Medical Sciences; National Institute of Allergy and Infectious Diseases; British Columbia Knowledge Development Fund; Office of Science; National Institutes of Health; Canadian Institutes of Health Research; Alliance de recherche numérique du Canada; University of California, San Francisco; U.S. Department of Energy","keywords":"ATG8; Biology; Cell biology; Autophagy; Docking (animal); Protein–protein interaction; Computational biology; Genetics","score_opus":0.011185392579472216,"score_gpt":0.28279868204452,"score_spread":0.2716132894650478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405889522","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99301744,0.0048407847,0.00018503326,0.00033089364,0.00014633096,0.00093433855,0.00011912698,0.00003893364,0.0003871379],"genre_scores_gemma":[0.9991981,0.000074116324,0.00014853978,0.00022171263,0.000036759702,0.000023310187,0.000009474449,0.000033267697,0.00025474114],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987124,0.00013321896,0.00039947702,0.00024390561,0.0003549518,0.00015600941],"domain_scores_gemma":[0.9989762,0.00011119584,0.0002205329,0.00047799663,0.00015726658,0.000056826495],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000081491395,0.00019964756,0.00045701847,0.00009081579,0.000057929887,0.000014569062,0.00017508652,0.00010353315,0.00018098444],"category_scores_gemma":[0.00003844653,0.00010126208,0.00018556607,0.00027205524,0.00043185736,0.00009534531,0.000059706406,0.0002427834,0.0000011388246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005370204,0.00009999795,0.00044135228,0.0007952295,0.0006743818,0.000030784824,0.0015495183,0.00004412469,0.9707253,0.023176432,0.000038653037,0.0018872162],"study_design_scores_gemma":[0.0022240644,0.00029135053,0.03988981,0.0005632412,0.0003162453,0.00003633914,0.00013618726,0.0012068908,0.9536773,0.0013177888,0.00024508304,0.00009571384],"about_ca_topic_score_codex":0.00023503337,"about_ca_topic_score_gemma":0.000018181874,"teacher_disagreement_score":0.039448455,"about_ca_system_score_codex":0.00002798744,"about_ca_system_score_gemma":0.00018590175,"threshold_uncertainty_score":0.41293478},"labels":[],"label_agreement":null},{"id":"W4405940844","doi":"10.3390/pharmaceutics17010042","title":"Liposomal Formulation of Hydroxychloroquine Can Inhibit Autophagy In Vivo","year":2024,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Simon Fraser University; BC Innovation Council; University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research; Uppsala Universitet; Mitacs","keywords":"Gefitinib; In vivo; Autophagy; Hydroxychloroquine; Pharmacology; Medicine; Liposome; Drug; Pharmacokinetics; Cancer; Cancer research; Chemistry; Internal medicine; Biology; Epidermal growth factor receptor; Biochemistry; Apoptosis; Coronavirus disease 2019 (COVID-19)","score_opus":0.031463986633859665,"score_gpt":0.356836516205137,"score_spread":0.3253725295712773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405940844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99150014,0.004259908,0.000083226674,0.0006636779,0.0003138065,0.0002938196,0.000032315977,0.00010968986,0.0027434437],"genre_scores_gemma":[0.99796337,0.00041306406,0.00012051973,0.0005229207,0.00020425649,0.000012704008,0.000020259808,0.00002824904,0.0007146807],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909395,0.00001883758,0.0002969369,0.00017276377,0.0002154218,0.00020211223],"domain_scores_gemma":[0.99962145,0.000046414854,0.00003624286,0.00015004024,0.000035484554,0.00011035531],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012618148,0.00012251579,0.0002031403,0.00019765407,0.00001750729,0.000010269216,0.000054290093,0.00006694116,0.0005495376],"category_scores_gemma":[0.00001438657,0.00011155837,0.00008787737,0.00034390978,0.000033976008,0.00008469152,0.000023626653,0.00018664196,0.000020746065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007973446,0.0008846123,0.014754396,0.0018258068,0.00043861437,0.0009835309,0.0035055925,0.00043244305,0.9103168,0.009438822,0.0012501576,0.055371884],"study_design_scores_gemma":[0.0018659636,0.00014292279,0.0037015767,0.00026821415,0.00016186398,0.000046218214,0.000032256154,0.06472771,0.90876013,0.0011056267,0.01905332,0.00013419957],"about_ca_topic_score_codex":0.000026052927,"about_ca_topic_score_gemma":0.000008185219,"teacher_disagreement_score":0.06429527,"about_ca_system_score_codex":0.000082066974,"about_ca_system_score_gemma":0.00013107408,"threshold_uncertainty_score":0.60170513},"labels":[],"label_agreement":null},{"id":"W4406226766","doi":"10.54254/2753-8818/2024.19966","title":"Experimental Design: Investigating the Role of Autophagy and BDNF in Neuronal Death Under Chronic Stress","year":2025,"lang":"en","type":"article","venue":"Theoretical and Natural Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Autophagy; Chronic stress; Stress (linguistics); Neuroscience; Psychology; Biology; Apoptosis; Genetics; Philosophy","score_opus":0.008698068657521403,"score_gpt":0.2943603567457875,"score_spread":0.28566228808826605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406226766","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99000186,0.0085204905,0.000044320725,0.000514216,0.000035450954,0.0001403907,8.6941816e-7,0.000008991773,0.00073338416],"genre_scores_gemma":[0.99931854,0.0000376357,0.00012583552,0.00047443973,0.000016865786,0.000004505845,3.8320428e-7,0.0000021263793,0.000019691306],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99936146,0.00003729324,0.0001040542,0.00016974218,0.00016347271,0.00016396551],"domain_scores_gemma":[0.9996563,0.00014702197,0.000018622528,0.000088279674,0.000017501523,0.00007228375],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023117823,0.00006934424,0.00010659757,0.000045514986,0.00010237687,0.000016619102,0.00010316751,0.00002463536,0.00003060945],"category_scores_gemma":[0.000061994404,0.000038565333,0.000015105338,0.00023379798,0.002484744,0.000058723814,0.000089389374,0.00013531408,3.3223478e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058395348,0.000034293593,0.0019574994,0.00000960359,0.000004314263,0.000002191352,0.00016103026,0.000005505988,0.29238346,0.70099217,7.6136325e-7,0.0043907845],"study_design_scores_gemma":[0.00051166356,0.00015216538,0.1402266,0.00009701392,0.00001183035,0.000008350569,0.00022982714,0.013143116,0.72754467,0.1180195,0.000005551495,0.000049723283],"about_ca_topic_score_codex":0.000012263192,"about_ca_topic_score_gemma":4.5454178e-7,"teacher_disagreement_score":0.58297265,"about_ca_system_score_codex":0.000027451895,"about_ca_system_score_gemma":0.00016605086,"threshold_uncertainty_score":0.91551423},"labels":[],"label_agreement":null},{"id":"W4406289977","doi":"10.1101/2025.01.09.631485","title":"Extracellular matrix mechanical cues (dys)regulate metabolic redox homeostasis due to impaired autophagic flux","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"Fundação para a Ciência e a Tecnologia; HORIZON EUROPE Framework Programme; European Regional Development Fund; Programa Operacional Regional do Centro; European Commission","keywords":"Autophagy; Cell biology; Bioenergetics; Extracellular matrix; Mitochondrion; Oxidative stress; Biology; Neurodegeneration; Flux (metallurgy); Programmed cell death; Context (archaeology); Chemistry; Endocrinology; Internal medicine; Biochemistry; Medicine; Disease; Apoptosis","score_opus":0.012959900517212592,"score_gpt":0.2605141988441209,"score_spread":0.2475542983269083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406289977","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9287114,0.060130354,0.0027063652,0.0018287046,0.0016573536,0.0027695736,0.0006000616,0.001579166,0.00001700339],"genre_scores_gemma":[0.9843627,0.0013257582,0.0107096275,0.00091972464,0.0010938105,0.00062528474,0.0000055621067,0.00027630647,0.00068122835],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9940946,0.00032444525,0.0012890595,0.0020558021,0.0009917726,0.0012443392],"domain_scores_gemma":[0.9940976,0.00010818658,0.00048846187,0.003324318,0.0007185144,0.0012629207],"candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00096249324,0.0012825597,0.0022054475,0.00096267153,0.0002739123,0.00024134154,0.0009819939,0.0012495547,0.0007231009],"category_scores_gemma":[0.00030005266,0.0013041885,0.00086153805,0.0012878685,0.00014738564,0.00016442011,0.00080542755,0.0013155029,0.00046238076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008523017,0.001208869,0.00049631245,0.0018617336,0.0029028885,0.003965086,0.00004888263,0.00010980457,0.97221607,0.012614441,0.0036387944,0.000084839514],"study_design_scores_gemma":[0.003009588,0.00027795456,0.0675638,0.0016457498,0.0026307362,9.112744e-7,0.000008497669,0.0009679005,0.87228096,0.000076317716,0.049594425,0.0019431692],"about_ca_topic_score_codex":0.00006762933,"about_ca_topic_score_gemma":0.0000012480799,"teacher_disagreement_score":0.0999351,"about_ca_system_score_codex":0.0004281423,"about_ca_system_score_gemma":0.0018705451,"threshold_uncertainty_score":0.9999926},"labels":[],"label_agreement":null},{"id":"W4406388982","doi":"10.1080/15548627.2024.2447206","title":"The ER protein CANX (calnexin)-mediated autophagy protects against alzheimer disease","year":2025,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Young Scientists Fund; National Natural Science Foundation of China; Ministry of Education, India; Zhejiang University; University of Alberta; Deutsche Forschungsgemeinschaft; Natural Science Foundation of Shandong Province; Strong","keywords":"Autophagy; ULK1; Cell biology; Biology; Calnexin; Hippocampal formation; Neuroscience; PSEN1; Endoplasmic reticulum; Protein kinase A; Calreticulin; Kinase; Alzheimer's disease; Presenilin; Disease; Internal medicine; Biochemistry; Medicine; AMPK","score_opus":0.011348306267561567,"score_gpt":0.2799612644313505,"score_spread":0.26861295816378894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406388982","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93142176,0.032434404,0.00043607844,0.008306386,0.0011454455,0.0067513045,0.00008512809,0.0011524254,0.018267062],"genre_scores_gemma":[0.96906817,0.00019425615,0.0001507556,0.0064212075,0.0002950127,0.0013397428,0.000106349165,0.00007828208,0.022346253],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9970978,0.00020376175,0.00059546833,0.00067891466,0.00057701935,0.0008470727],"domain_scores_gemma":[0.99759555,0.00020760807,0.00016842861,0.0012481721,0.0002147906,0.00056547794],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003672229,0.00047299577,0.0004966502,0.00019683596,0.0006234404,0.00010761141,0.00044851901,0.00021645227,0.0003184552],"category_scores_gemma":[0.00038621982,0.00032728954,0.00033454347,0.0007347288,0.00036569985,0.00014675157,0.00014649103,0.0005385534,0.00049189694],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013254681,0.005639971,0.004191296,0.0011285784,0.009260359,0.007646607,0.001245966,0.00017490644,0.17681366,0.089853674,0.086688474,0.60410184],"study_design_scores_gemma":[0.010368423,0.0005178026,0.18484609,0.00094029633,0.0010072374,0.000022495049,0.00014267882,0.007464501,0.26465636,0.010062567,0.5187293,0.0012422226],"about_ca_topic_score_codex":0.000073171585,"about_ca_topic_score_gemma":0.000013412774,"teacher_disagreement_score":0.6028596,"about_ca_system_score_codex":0.00014244633,"about_ca_system_score_gemma":0.0012985502,"threshold_uncertainty_score":0.9999179},"labels":[],"label_agreement":null},{"id":"W4406450162","doi":"10.1016/j.devcel.2024.12.039","title":"mTor limits autophagy to facilitate cell volume expansion and rapid wound repair in Drosophila embryos","year":2025,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ted Rogers Centre for Heart Research; University of Toronto","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canada Foundation for Innovation","keywords":"Biology; Autophagy; Drosophila (subgenus); PI3K/AKT/mTOR pathway; Cell biology; Embryo; Genetics; Signal transduction; Gene; Apoptosis","score_opus":0.019614997371234358,"score_gpt":0.24741848325209093,"score_spread":0.22780348588085658,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406450162","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9788444,0.0018440717,0.000030986692,0.00041157493,0.00024988587,0.0007440321,0.000023800947,0.00014254297,0.017708687],"genre_scores_gemma":[0.9400886,0.0002113934,0.0028350363,0.0033897285,0.00003526482,0.000077666904,0.000049407252,0.000024433619,0.053288464],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9984732,0.000043468764,0.0003916039,0.00050871546,0.00021735564,0.00036561367],"domain_scores_gemma":[0.9994042,0.00004054954,0.000040862244,0.0002304602,0.00004045859,0.00024345618],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018161218,0.0002527293,0.00034155237,0.00028425208,0.0001008053,0.000018278137,0.000099648765,0.00012773348,0.00026692214],"category_scores_gemma":[0.000022562606,0.00024636407,0.0000824237,0.0003863106,0.00005435184,0.0000927859,0.00010003033,0.00018483587,0.00030448262],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033479745,0.0030259585,0.07983384,0.002300782,0.0002803169,0.001952717,0.01717782,0.000023428696,0.73751295,0.00012876197,0.10590712,0.0485083],"study_design_scores_gemma":[0.0059296824,0.00043305955,0.5680259,0.00031208937,0.000058057787,0.000023583627,0.0011863246,0.00024029001,0.28836462,0.0002619877,0.13459575,0.0005686646],"about_ca_topic_score_codex":0.00004409019,"about_ca_topic_score_gemma":0.00000850561,"teacher_disagreement_score":0.48819205,"about_ca_system_score_codex":0.00021596951,"about_ca_system_score_gemma":0.00035175146,"threshold_uncertainty_score":0.99999887},"labels":[],"label_agreement":null},{"id":"W4406483704","doi":"10.1249/jes.0000000000000358","title":"Focus on the Forgotten Organelle: Regulation of Lysosomes in Skeletal Muscle","year":2025,"lang":"en","type":"review","venue":"Exercise and Sport Sciences Reviews","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Autophagy; Lysosome; Organelle; Skeletal muscle; Cell biology; Homeostasis; Mitochondrion; Biology; Endocrinology; Biochemistry; Enzyme","score_opus":0.04139126027896285,"score_gpt":0.34458440664169354,"score_spread":0.3031931463627307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406483704","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00061870733,0.99365383,0.0000014328591,0.00013150637,0.00009010972,0.0019675817,0.0000059956196,0.000009628512,0.0035212124],"genre_scores_gemma":[0.00061145396,0.99756366,0.000047485522,0.000093657385,0.000056179364,0.00012920702,0.000021223175,0.000009891314,0.0014672132],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982416,0.00006236296,0.0008069027,0.0004012893,0.0002940988,0.00019371937],"domain_scores_gemma":[0.9989652,0.00010857529,0.00040233927,0.0004345178,0.000024968396,0.000064372776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011263188,0.00027039513,0.0019358421,0.0002675314,0.000102158505,0.000019323921,0.00025903384,0.0001255676,0.0002530163],"category_scores_gemma":[0.00007251393,0.00013246485,0.00038193056,0.0010984046,0.0002513444,0.00006467751,0.000049812017,0.0001813057,0.000025015466],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000034909335,0.000054232307,0.0000738999,0.006151873,0.000009271551,0.00000690756,0.000046630663,8.0220296e-8,3.795348e-7,0.0010019935,0.000607132,0.9920441],"study_design_scores_gemma":[0.00014100054,0.000082195846,0.0012283076,0.052125115,0.00042293503,0.000006359902,0.000024638102,0.0000043870946,0.000007492041,0.00050708547,0.94530916,0.0001413169],"about_ca_topic_score_codex":0.000016400214,"about_ca_topic_score_gemma":0.0000027575043,"teacher_disagreement_score":0.99190277,"about_ca_system_score_codex":0.00002610573,"about_ca_system_score_gemma":0.00032634934,"threshold_uncertainty_score":0.540176},"labels":[],"label_agreement":null},{"id":"W4406563428","doi":"10.1016/j.abdp.2022.10.001","title":"10.1016/j.abdp.2022.10.001","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"PI3K/AKT/mTOR pathway; Protein kinase B; Medicine; Biology; Cell biology; Phosphorylation; Signal transduction","score_opus":0.00595732815866537,"score_gpt":0.2069936345739664,"score_spread":0.20103630641530104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406563428","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005643328,0.0004548293,2.318556e-7,0.00054369884,0.0000017502393,0.00025033584,0.000018405834,0.0001774877,0.9929099],"genre_scores_gemma":[0.0005165794,0.0000022546008,0.00003228963,0.00038097578,0.00031641484,0.000026446312,0.00006666433,0.000033617835,0.99862474],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99911195,0.00002351598,0.00015819845,0.00022004345,0.0002188943,0.00026740614],"domain_scores_gemma":[0.99924165,0.000026746116,0.000020498745,0.00038234625,0.00004173638,0.0002869957],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0000787246,0.00014252446,0.00021413536,0.00006529815,0.0000586963,0.000014417908,0.00011359298,0.00006905903,0.9997888],"category_scores_gemma":[0.000019929947,0.00012561424,0.00009107196,0.00017679275,0.0000332874,0.000050681956,0.000018051087,0.00010579403,0.99751174],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004220495,0.00016803217,2.0295984e-7,0.000009097532,0.00005288678,0.0000546699,0.00000886954,0.0000028982577,0.00015124018,8.7365186e-7,0.50184214,0.49728703],"study_design_scores_gemma":[0.001078223,0.0003821108,0.00017257725,0.000028443996,0.00006728866,0.000022450451,6.90476e-7,0.00007874452,0.0005077392,0.000017063316,0.99750453,0.00014014023],"about_ca_topic_score_codex":0.000012073932,"about_ca_topic_score_gemma":4.128863e-8,"teacher_disagreement_score":0.4971469,"about_ca_system_score_codex":0.000036278434,"about_ca_system_score_gemma":0.000052822328,"threshold_uncertainty_score":0.51224},"labels":[],"label_agreement":null},{"id":"W4406676917","doi":"10.3390/ijms26020793","title":"HERC1 E3 Ubiquitin Ligase Is Necessary for Autophagy Processes and for the Maintenance and Homeostasis of Vesicles in Motor Nerve Terminals, but Not for Proteasomal Activity","year":2025,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Agencia Estatal de Investigación; Ministerio de Ciencia e Innovación; Ministerio de Economía y Competitividad; Junta de Andalucía; European Commission","keywords":"Ubiquitin ligase; Autophagy; Cell biology; Ubiquitin; Biology; Neuromuscular junction; Homeostasis; Neurotransmitter; Synaptic vesicle; Proteasome; Endocrinology; Biochemistry; Neuroscience; Central nervous system; Vesicle; Gene","score_opus":0.023424048141544536,"score_gpt":0.34332551858862004,"score_spread":0.3199014704470755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406676917","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97548753,0.0040033045,0.010557533,0.009109367,0.00010774936,0.0006224868,0.00009987262,0.0000021383,0.000010028104],"genre_scores_gemma":[0.99596924,0.00022400613,0.002627497,0.00098284,0.000057064783,0.000077503966,7.777621e-7,0.0000046220325,0.00005647129],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918365,0.000018179557,0.0002574761,0.00014502482,0.00027636546,0.00011931459],"domain_scores_gemma":[0.99872524,0.00045764662,0.00024890518,0.000054825723,0.00047351318,0.00003984809],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004880981,0.000084249004,0.00019396142,0.00012591375,0.00006662423,0.000044340624,0.00023562714,0.000029919596,0.0000019501722],"category_scores_gemma":[0.00054293126,0.00005484743,0.000078463905,0.00010378624,0.00020414643,0.00015182974,0.00003332206,0.000055381875,1.2586737e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013146664,0.0008170956,0.0067918086,0.0019184751,0.0010136263,0.00017207254,0.0011304365,0.00010907885,0.6193311,0.0065427152,0.00074501196,0.34828186],"study_design_scores_gemma":[0.002486763,0.0006557974,0.03377623,0.00055327866,0.00007976016,0.00006722316,0.00050804706,0.0022071635,0.95257825,0.006715143,0.00030175433,0.00007058371],"about_ca_topic_score_codex":0.00020372275,"about_ca_topic_score_gemma":0.00007419159,"teacher_disagreement_score":0.3482113,"about_ca_system_score_codex":0.000029871822,"about_ca_system_score_gemma":0.00071359205,"threshold_uncertainty_score":0.22366133},"labels":[],"label_agreement":null},{"id":"W4406940291","doi":"10.1101/2025.01.28.635321","title":"Endurance training restores ageing-impaired lysosomal biogenesis factors in rest and response to acute exercise in rat skeletal muscle","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Endurance training; Ageing; Rest (music); Training (meteorology); Skeletal muscle; Biogenesis; Medicine; Internal medicine; Physical medicine and rehabilitation; Endocrinology; Chemistry; Biochemistry","score_opus":0.019126610657028857,"score_gpt":0.25744081434860416,"score_spread":0.2383142036915753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406940291","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99355096,0.0032120612,0.000024832423,0.00042735093,0.0006330092,0.0015329246,0.00035378948,0.0002613779,0.0000036852182],"genre_scores_gemma":[0.9971745,0.0009529616,0.0009755764,0.00026623305,0.0001278271,0.00036772987,0.0000014963773,0.00010703842,0.00002660687],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9963376,0.00032653075,0.00079118786,0.0013411682,0.00042793012,0.00077559554],"domain_scores_gemma":[0.9976372,0.00021592705,0.00022754761,0.0012345739,0.00015876681,0.00052597583],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00079264917,0.00072502135,0.0011802382,0.0013365926,0.000119674194,0.000102634694,0.0003999757,0.00064029696,0.000025215115],"category_scores_gemma":[0.000531085,0.0007612843,0.0002035775,0.0012179882,0.00015753071,0.00014946297,0.00037452945,0.0007592639,0.000008682844],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002429133,0.00030962197,0.057182252,0.0005931126,0.00018571982,0.002631905,0.0005547691,0.00005110294,0.93590665,0.000028839597,0.00007497493,0.00005189839],"study_design_scores_gemma":[0.0018570579,0.00008969259,0.8817948,0.0029839564,0.00018141484,4.5903523e-8,0.000043668093,0.00007703191,0.11166812,0.000001738316,0.00068989396,0.0006125533],"about_ca_topic_score_codex":0.0002692715,"about_ca_topic_score_gemma":0.000039901057,"teacher_disagreement_score":0.82461256,"about_ca_system_score_codex":0.00049261836,"about_ca_system_score_gemma":0.0013393905,"threshold_uncertainty_score":0.9994838},"labels":[],"label_agreement":null},{"id":"W4407136219","doi":"10.1152/ajpregu.00232.2024","title":"The effect of an exercise- and passive-induced heat stress on autophagy in young and older males","year":2025,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; Université de Sherbrooke; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Heat shock; Apoptosis; Medicine; Heat shock protein; Inflammation; Heat stress; Internal medicine; Western blot; Oxidative stress; Core temperature; Endocrinology; Hsp70; Peripheral blood mononuclear cell; Chemistry; Biology; Animal science; Biochemistry","score_opus":0.009410089147465234,"score_gpt":0.3092294557379797,"score_spread":0.2998193665905145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407136219","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99725735,0.0019891378,0.000007438236,0.00016410818,0.00011508297,0.00034616626,0.000010054844,0.0000069769767,0.00010366938],"genre_scores_gemma":[0.99913317,0.0005325299,0.000039183877,0.00015575821,0.000064509724,0.000029825236,0.0000058420787,0.000009512316,0.000029681236],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980617,0.0007455465,0.00047334892,0.00034593037,0.000121463825,0.00025199723],"domain_scores_gemma":[0.99834985,0.00073324295,0.00037207178,0.00024530137,0.0001730938,0.00012642256],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001736244,0.00033188777,0.0013857721,0.00021205892,0.00014565815,0.000011674925,0.00014629986,0.00008183963,0.000009462595],"category_scores_gemma":[0.00003398324,0.00018108948,0.000118485535,0.00021848222,0.0019510558,0.00010718986,0.000052464165,0.00043460698,4.8847807e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.010506673,0.00035934913,0.013657514,0.000088578745,0.0007848421,0.000011522437,0.0026345896,0.00004696627,0.9511769,0.0030881707,0.000076362536,0.017568568],"study_design_scores_gemma":[0.0021223454,0.00797996,0.7738116,0.0004902865,0.000112668866,0.000019226101,0.0038558294,0.00029637673,0.21009953,0.0010838698,0.000010557771,0.000117759795],"about_ca_topic_score_codex":0.0000838298,"about_ca_topic_score_gemma":0.000035302855,"teacher_disagreement_score":0.76015407,"about_ca_system_score_codex":0.000037074253,"about_ca_system_score_gemma":0.00009440197,"threshold_uncertainty_score":0.7384615},"labels":[],"label_agreement":null},{"id":"W4407772349","doi":"10.1186/s12929-025-01118-w","title":"Mitophagy is required to protect against excessive skeletal muscle atrophy following hindlimb immobilization","year":2025,"lang":"en","type":"article","venue":"Journal of Biomedical Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Universities Space Research Association","keywords":"Hindlimb; Muscle atrophy; Skeletal muscle; Atrophy; Mitophagy; Medicine; Physical medicine and rehabilitation; Anatomy; Internal medicine; Biology; Autophagy; Biochemistry; Apoptosis","score_opus":0.009092661751702914,"score_gpt":0.3169502869961206,"score_spread":0.3078576252444177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407772349","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98362046,0.0006802336,0.0083336895,0.0053772414,0.001064644,0.000328336,0.0000025970319,0.000019569692,0.0005731977],"genre_scores_gemma":[0.99387914,0.00004759444,0.0016481533,0.0038400802,0.00032423565,0.0000073954966,0.0000013156166,0.000007244195,0.00024483062],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976386,0.000039086957,0.00052244606,0.00026294662,0.0012001452,0.00033679386],"domain_scores_gemma":[0.9987006,0.0000513676,0.00021344474,0.0002234024,0.00026696885,0.0005441935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008324203,0.000126879,0.0003166709,0.0005450663,0.00021325798,0.000053230866,0.00040562009,0.000084979205,0.00008441041],"category_scores_gemma":[0.0006902666,0.000089172885,0.00025039839,0.0020732954,0.0004025395,0.0002985309,0.00008717146,0.000214624,0.000017727785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001704345,0.0004413178,0.0004874454,0.000059206523,0.000104499704,0.0005243169,0.00057947537,0.0000062063423,0.79380995,0.00006815287,0.0024521425,0.20129684],"study_design_scores_gemma":[0.018079875,0.0094580995,0.31339455,0.0056192866,0.00061158335,0.00032018105,0.0019616873,0.0035422605,0.48149258,0.006006229,0.15831049,0.0012031969],"about_ca_topic_score_codex":0.000004974459,"about_ca_topic_score_gemma":2.704149e-7,"teacher_disagreement_score":0.3129071,"about_ca_system_score_codex":0.00022695713,"about_ca_system_score_gemma":0.0011320084,"threshold_uncertainty_score":0.36363646},"labels":[],"label_agreement":null},{"id":"W4407830436","doi":"10.1371/journal.pbio.3003034","title":"Caspase 3 and caspase 7 promote cytoprotective autophagy and the DNA damage response during non-lethal stress conditions in human breast cancer cells","year":2025,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University; Genome British Columbia; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Autophagy; DNA damage; Apoptosis; Caspase; Programmed cell death; Cell biology; Cancer; Cancer cell; Cancer research; Fight-or-flight response; Breast cancer; Caspase 8; DNA; Genetics; Gene","score_opus":0.006845743461844484,"score_gpt":0.2949086056821146,"score_spread":0.2880628622202701,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407830436","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99594676,0.00052693026,0.000005848352,0.001868657,0.00005470643,0.0009630105,0.00044359127,0.000033898035,0.00015660067],"genre_scores_gemma":[0.9987293,0.000088750574,0.000011538676,0.00038664447,0.000066959874,0.00031081584,0.000022111795,0.000013167992,0.000370733],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99885,0.00030396826,0.00020177232,0.00033915462,0.00005379222,0.00025133885],"domain_scores_gemma":[0.9993535,0.00018892228,0.000064061554,0.00025561053,0.00005050789,0.000087345754],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019479952,0.0001678115,0.00034117367,0.00017099622,0.00021246758,0.00001359303,0.00007571883,0.00013835721,0.000115766],"category_scores_gemma":[0.000047892994,0.00011755377,0.000040442737,0.00015786575,0.0005819137,0.00004095264,0.00008785191,0.00028409634,0.000002380227],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0049968488,0.00028488415,0.0057066646,0.00015856265,0.00026302083,0.00057873584,0.0013484915,0.0000031030795,0.9857919,0.00064127194,0.000015238379,0.00021127608],"study_design_scores_gemma":[0.007935423,0.00015005993,0.57803106,0.00025298426,0.00013648794,0.0000853857,0.00026121488,0.0002692988,0.41169047,0.0010458129,0.000013094197,0.00012873148],"about_ca_topic_score_codex":0.0007264485,"about_ca_topic_score_gemma":0.0001963276,"teacher_disagreement_score":0.57410145,"about_ca_system_score_codex":0.00007041757,"about_ca_system_score_gemma":0.00011969838,"threshold_uncertainty_score":0.47937036},"labels":[],"label_agreement":null},{"id":"W4407900743","doi":"10.1038/s44321-025-00204-8","title":"X-linked myopathy with excessive autophagy: characterization and therapy testing in a zebrafish model","year":2025,"lang":"en","type":"article","venue":"EMBO Molecular Medicine","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Neurological Disorders and Stroke; NIH Office of the Director; National Institute on Aging; National Institutes of Health; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Zebrafish; Autophagy; Phenocopy; Myopathy; Biology; Vacuole; Cell biology; Mutant; Cancer research; Genetics; Apoptosis","score_opus":0.014838839902937417,"score_gpt":0.27565824909569897,"score_spread":0.26081940919276153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407900743","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97309,0.0029283722,0.01846976,0.0026571632,0.000058484635,0.00063246285,0.0000029631826,0.00009515092,0.0020656488],"genre_scores_gemma":[0.9893935,0.00027209803,0.00073984906,0.008919636,0.00007264052,0.00007478771,0.00007466464,0.000031730055,0.00042112786],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9987775,0.00005327482,0.00029814066,0.00036941242,0.00025935564,0.00024229586],"domain_scores_gemma":[0.999302,0.00005189106,0.000098939694,0.00029577067,0.00012717376,0.00012418434],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018374402,0.00022448762,0.00043597512,0.0002804294,0.000057565827,0.000012222001,0.00007955339,0.00009820964,0.000031795316],"category_scores_gemma":[0.00013721672,0.00016231726,0.000028626117,0.0006210692,0.00015170293,0.000080481084,0.000024502175,0.00021642263,0.0000014796884],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007510771,0.00024693142,0.008283378,0.00014723468,0.00015434962,0.00085452665,0.001159642,0.0000934163,0.94016474,0.0011872168,0.00004188722,0.046915624],"study_design_scores_gemma":[0.033104707,0.0022017157,0.74516904,0.0046676015,0.00039046994,0.00015188112,0.00039362742,0.12260914,0.085005455,0.004677329,0.0009518949,0.0006771116],"about_ca_topic_score_codex":0.000025647209,"about_ca_topic_score_gemma":0.0000014153861,"teacher_disagreement_score":0.8551593,"about_ca_system_score_codex":0.000038366074,"about_ca_system_score_gemma":0.0002084946,"threshold_uncertainty_score":0.6619106},"labels":[],"label_agreement":null},{"id":"W4407972867","doi":"10.1139/bcb-2025-0020","title":"Retraction: Active vitamin D activates chondrocyte autophagy to reduce osteoarthritis via mediating the AMPK–mTOR signaling pathway","year":2025,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":true,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autophagy; AMPK; PI3K/AKT/mTOR pathway; Chondrocyte; Osteoarthritis; Cell biology; Chemistry; Vitamin D and neurology; Signal transduction; Medicine; Cartilage; Protein kinase A; Phosphorylation; Endocrinology; Biology; Biochemistry; Anatomy; Pathology; Apoptosis","score_opus":0.006672896247320102,"score_gpt":0.25400655613601364,"score_spread":0.24733365988869355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407972867","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99100953,0.0026107626,0.00011337954,0.0011138121,0.0004468762,0.0002781771,0.000032729353,0.000059252972,0.004335455],"genre_scores_gemma":[0.9952166,0.00013402823,0.0001566274,0.0010906693,0.0004977493,0.00007293094,0.00007949712,0.0000115952835,0.002740323],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989873,0.00005531151,0.00022018938,0.00039716726,0.00007677478,0.00026326755],"domain_scores_gemma":[0.999219,0.00018422057,0.00009292778,0.0003054682,0.00006477424,0.0001336361],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012612919,0.00018885071,0.00024974343,0.000040759853,0.00021746999,0.000016910368,0.00013517994,0.00031341967,0.00013464267],"category_scores_gemma":[0.00013487818,0.0001422201,0.00007892174,0.00019219202,0.0001364864,0.000033102093,0.00008291218,0.0003193451,0.000011657935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037861252,0.00006110474,0.00009400339,0.00006407004,0.000056470923,0.000015673168,0.00015052051,4.382156e-7,0.9363936,0.000019583349,0.00027231977,0.06249357],"study_design_scores_gemma":[0.0009526879,0.00019477222,0.00060354476,0.00007551197,0.00004702012,0.000024474306,0.00048789728,0.000013543925,0.9878187,0.00017281236,0.009474395,0.00013463879],"about_ca_topic_score_codex":0.000012680347,"about_ca_topic_score_gemma":5.210865e-7,"teacher_disagreement_score":0.06235893,"about_ca_system_score_codex":0.000054098702,"about_ca_system_score_gemma":0.00014025286,"threshold_uncertainty_score":0.5799567},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"not_applicable","genre":"other","about_ca_system":false,"about_ca_topic":false,"confidence":"high"},{"model":"gpt","categories":["research_integrity"],"domain":null,"study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"high"}],"label_agreement":"split"},{"id":"W4408289342","doi":"10.1080/15548627.2025.2476872","title":"The mitophagy receptor BNIP3L/Nix coordinates nuclear calcium signaling to modulate the muscle phenotype","year":2025,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Children's Hospital Research Institute of Manitoba; Canadian Diabetes Association; Canada Research Chairs; Diabetes Canada","keywords":"Mitophagy; Biology; Phenotype; Cell biology; Signal transduction; Autophagy; Neuroscience; Genetics; Apoptosis; Gene","score_opus":0.011855668748029098,"score_gpt":0.2843859901194727,"score_spread":0.27253032137144356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408289342","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9695331,0.0052049775,0.00040874584,0.014758575,0.0016108025,0.0010277979,0.000015790409,0.00033177645,0.007108429],"genre_scores_gemma":[0.9756571,0.00012833806,0.00026216163,0.009257472,0.0004283466,0.000078771714,0.000010137473,0.000057930665,0.014119761],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980647,0.0001277425,0.0004159367,0.00045674908,0.0003432582,0.00059164467],"domain_scores_gemma":[0.99819267,0.00038718776,0.00009432495,0.00094331364,0.00017374588,0.00020873907],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041396168,0.0002974289,0.00035842715,0.00009964792,0.0008498611,0.00012629211,0.0005348765,0.00014101349,0.00074011594],"category_scores_gemma":[0.00021040064,0.00017597887,0.0002438795,0.00063534,0.00019343065,0.00008327186,0.00016902456,0.00035606333,0.0006252375],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019750965,0.00067596056,0.0006420463,0.00017779782,0.0017436815,0.00018106912,0.0032416736,0.0006050829,0.5412779,0.062223624,0.13780998,0.24944608],"study_design_scores_gemma":[0.002780452,0.0005392971,0.04022055,0.000273007,0.0003383291,0.000012170169,0.00081017095,0.002908571,0.16661285,0.006597119,0.77837706,0.0005304311],"about_ca_topic_score_codex":0.00011823248,"about_ca_topic_score_gemma":0.0000049519786,"teacher_disagreement_score":0.64056706,"about_ca_system_score_codex":0.0001140977,"about_ca_system_score_gemma":0.00016952076,"threshold_uncertainty_score":0.81037503},"labels":[],"label_agreement":null},{"id":"W4408362407","doi":"10.7554/elife.105834","title":"Transcriptional dynamics uncover the role of BNIP3 in mitophagy during muscle remodeling in Drosophila","year":2025,"lang":"en","type":"article","venue":"eLife","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Precursory Research for Embryonic Science and Technology; Research Institute for Information Technology, Kyushu University; Japan Science and Technology Agency; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Association of Medical Research Charities; Japan Agency for Medical Research and Development; McGill University","keywords":"Mitophagy; Drosophila (subgenus); Dynamics (music); Cell biology; Drosophila melanogaster; Biology; Genetics; Autophagy; Gene","score_opus":0.005272672771354231,"score_gpt":0.24957694239105396,"score_spread":0.24430426961969973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408362407","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928786,0.0029579038,0.00006395668,0.0006965807,0.0000983965,0.00017725791,0.00000804021,0.000014888914,0.0031043824],"genre_scores_gemma":[0.99879473,0.00019298759,0.000077088866,0.00054331985,0.00006301029,0.000013437374,0.000009566136,0.000009345954,0.00029652313],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99919397,0.000030455893,0.00026778667,0.00014180405,0.00022274168,0.00014321844],"domain_scores_gemma":[0.9996766,0.000037185757,0.000031304753,0.00019255116,0.0000336058,0.000028773538],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014739913,0.00008236328,0.0001731255,0.00013076555,0.000029244573,0.0000043973264,0.00008882194,0.00006322808,0.000038271817],"category_scores_gemma":[0.0000305251,0.000065852146,0.00007585982,0.000265114,0.00003796167,0.000046065597,0.000016155107,0.00017289903,0.0000030240622],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023373042,0.0017212911,0.3740395,0.00046956743,0.00023601929,0.0001592183,0.0037971367,0.016050892,0.52195203,0.055714015,0.000082625906,0.023440419],"study_design_scores_gemma":[0.0031327126,0.000029494784,0.9227395,0.00034844328,0.000026100877,0.0000037436087,0.0006096003,0.039379295,0.02449472,0.008407671,0.00072882645,0.00009988503],"about_ca_topic_score_codex":0.000069223184,"about_ca_topic_score_gemma":0.00007677648,"teacher_disagreement_score":0.54870003,"about_ca_system_score_codex":0.000095427895,"about_ca_system_score_gemma":0.000122052516,"threshold_uncertainty_score":0.26853725},"labels":[],"label_agreement":null},{"id":"W4408362416","doi":"10.7554/elife.105834.1.sa1","title":"Reviewer #2 (Public review): Transcriptional Dynamics Uncover the Role of BNIP3 in Mitophagy during Muscle Remodeling in Drosophila","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Precursory Research for Embryonic Science and Technology; Research Institute for Information Technology, Kyushu University; Japan Science and Technology Agency; Ministry of Education, Culture, Sports, Science and Technology; Japan Agency for Medical Research and Development; McGill University","keywords":"Mitophagy; Drosophila (subgenus); Dynamics (music); Cell biology; Biology; Gene; Autophagy; Genetics; Sociology","score_opus":0.01873724169953344,"score_gpt":0.29793295173583156,"score_spread":0.2791957100362981,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408362416","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00171258,0.9413076,0.000030604187,0.03927469,0.00096062914,0.002549812,0.00020110456,0.0000392052,0.013923767],"genre_scores_gemma":[0.006489869,0.9198011,0.00012461832,0.018644325,0.00042254484,0.0002905155,0.0010998313,0.00006324057,0.05306393],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.9959256,0.00027960664,0.0017331317,0.0006413821,0.0009753787,0.0004448944],"domain_scores_gemma":[0.9975715,0.00013215482,0.0003634794,0.0010967297,0.0007179062,0.00011818791],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001274198,0.0005101146,0.0019158727,0.00035794955,0.000051257026,0.00001213167,0.0005063018,0.00033134856,0.0015117512],"category_scores_gemma":[0.0008078711,0.00035814953,0.00074815593,0.0010454273,0.000089605266,0.00011540046,0.00009004731,0.0010658057,0.000013912816],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035330033,0.0025721428,0.0014031829,0.3905836,0.00095979945,0.00023181541,0.00022569105,0.00012261515,0.0009043097,0.008618114,0.34592584,0.2480996],"study_design_scores_gemma":[0.001494664,0.000042435142,0.0037228127,0.16526407,0.0005263853,0.000016008189,0.00002429167,0.0010132684,0.000042007574,0.0014811443,0.82597035,0.00040259073],"about_ca_topic_score_codex":0.00016477189,"about_ca_topic_score_gemma":0.00029291984,"teacher_disagreement_score":0.48004448,"about_ca_system_score_codex":0.00040368128,"about_ca_system_score_gemma":0.0008971489,"threshold_uncertainty_score":0.99988705},"labels":[],"label_agreement":null},{"id":"W4408362951","doi":"10.3390/cells14060418","title":"Autophagy and Respiratory Viruses: Mechanisms, Viral Exploitation, and Therapeutic Insights","year":2025,"lang":"en","type":"review","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Children's Hospital Research Institute of Manitoba; University of Manitoba; Health Sciences Centre; Memorial University of Newfoundland","funders":"","keywords":"Rhinovirus; Autophagy; Biology; Viral replication; Virus; Immune system; Virology; Viral pathogenesis; Respiratory system; Immunology","score_opus":0.04536523309043718,"score_gpt":0.34313623911842617,"score_spread":0.297771006027989,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408362951","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022521007,0.9973419,0.00014183168,0.000006795564,0.0002877777,0.0009482981,0.000021195328,0.000084800784,0.0009421909],"genre_scores_gemma":[0.00006939798,0.99487734,0.0001336555,0.0032331792,0.00013547794,0.00012482096,0.000018861332,0.000051422565,0.0013558584],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99856603,0.00015772754,0.00042882524,0.00047246067,0.00017590166,0.00019905508],"domain_scores_gemma":[0.9990104,0.00020945842,0.00016431832,0.00039712508,0.00004949052,0.00016919908],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011722262,0.00038968658,0.0011707128,0.00026512938,0.000109693596,0.000039665174,0.00010070489,0.00032532998,0.000106639214],"category_scores_gemma":[0.000018377816,0.00029683483,0.00018199382,0.00017754744,0.00010491332,0.000054135522,0.00005932322,0.00026480926,0.000048731014],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030006966,0.000101192236,6.2785205e-7,0.020245094,0.00048763957,0.00011920031,0.00026908924,3.7094832e-8,0.00026509262,0.0063817366,0.00063694885,0.9714633],"study_design_scores_gemma":[0.0006496147,0.00019710814,0.000009001252,0.0061255605,0.0014678456,0.000011562102,0.000033020933,0.0000022463228,0.0008543935,0.0042355387,0.9861485,0.00026560758],"about_ca_topic_score_codex":0.000002737234,"about_ca_topic_score_gemma":5.748334e-7,"teacher_disagreement_score":0.98551154,"about_ca_system_score_codex":0.000049483246,"about_ca_system_score_gemma":0.00041805356,"threshold_uncertainty_score":0.9999484},"labels":[],"label_agreement":null},{"id":"W4408573771","doi":"10.32388/fasjsq","title":"Endurance Training Restores Ageing-Impaired Lysosomal Biogenesis Factors in Rest and Response to Acute Exercise in Rat Skeletal Muscle","year":2025,"lang":"en","type":"preprint","venue":"Qeios","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Endurance training; Rest (music); Ageing; Training (meteorology); Skeletal muscle; Internal medicine; Medicine; Endocrinology; Physical medicine and rehabilitation","score_opus":0.02875867153313937,"score_gpt":0.30282232052831676,"score_spread":0.2740636489951774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408573771","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947452,0.0023745152,0.000010348843,0.0007832675,0.00041525267,0.0012793812,0.00019251609,0.00010892209,0.00009057211],"genre_scores_gemma":[0.99739295,0.00073504023,0.00029968028,0.0002713369,0.00008251046,0.00023639473,0.000082487066,0.000044006905,0.00085561455],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9976329,0.00024366414,0.00053861225,0.0008108007,0.00030148725,0.00047252144],"domain_scores_gemma":[0.99862427,0.0002415459,0.00011572579,0.0006959516,0.00004349279,0.00027899805],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004139983,0.00043622535,0.0008678374,0.0008713853,0.000065343214,0.00003997732,0.00024711434,0.0004068279,0.000045342975],"category_scores_gemma":[0.0003160601,0.00041931137,0.00018169059,0.00047103062,0.0000946938,0.00006865123,0.0002893582,0.0005292322,0.000006716635],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.039229695,0.0017711832,0.20636998,0.002939107,0.0009979765,0.02318784,0.10324594,0.0008280987,0.4904538,0.000090530724,0.0018848081,0.12900104],"study_design_scores_gemma":[0.0022120324,0.0001172653,0.98252887,0.003307674,0.00014305826,0.000006689993,0.0007798995,0.000106741456,0.0093161315,0.00012596072,0.0009516263,0.0004040424],"about_ca_topic_score_codex":0.00051878014,"about_ca_topic_score_gemma":0.00025706267,"teacher_disagreement_score":0.7761589,"about_ca_system_score_codex":0.00023292642,"about_ca_system_score_gemma":0.0005774098,"threshold_uncertainty_score":0.9998259},"labels":[],"label_agreement":null},{"id":"W4408644877","doi":"10.1080/27694127.2025.2464986","title":"Autophagy machinery as exploited by viruses","year":2025,"lang":"en","type":"article","venue":"Autophagy Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Mental Health; Natural Sciences and Engineering Research Council of Canada; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Novo Nordisk Foundation Center for Basic Metabolic Research; Novo Nordisk; Agence Nationale de Recherches sur le Sida et les Hépatites Virales; Agence Nationale de la Recherche; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Styrelsen för Internationellt Utvecklingssamarbete; Helmholtz-Gemeinschaft; International Maternal Pediatric Adolescent AIDS Clinical Trials Network; Deutsche Forschungsgemeinschaft; National Science Foundation","keywords":"Autophagy; Cell biology; Lytic cycle; Biology; Cytosol; Viral replication; Mechanism (biology); ATG8; Vacuole; Virus; Virology; Biochemistry; Apoptosis","score_opus":0.008357498702238952,"score_gpt":0.3102255174672757,"score_spread":0.30186801876503677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408644877","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9427399,0.0077266484,0.00029232327,0.00081306766,0.0012313458,0.000633863,0.0000130761455,0.00082126976,0.045728493],"genre_scores_gemma":[0.9416098,0.0001992149,0.00020325577,0.012945104,0.00017505858,0.00013737025,0.0001303374,0.000062923675,0.044536907],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972891,0.000070410264,0.000846413,0.0007744995,0.00048291858,0.00053664023],"domain_scores_gemma":[0.99801266,0.00010792193,0.0002695138,0.0011560572,0.00013946278,0.00031437224],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002801288,0.00041064539,0.0006641769,0.0002932922,0.00019313414,0.000057666308,0.0001528195,0.00026223366,0.0018976537],"category_scores_gemma":[0.00027726192,0.0003665539,0.0003279704,0.00060651114,0.00014752558,0.00019790241,0.00010052751,0.00034021272,0.00022207727],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012096645,0.003643868,0.07478801,0.00053345296,0.002819991,0.03916344,0.0005308669,0.000023844348,0.40567473,0.0075467397,0.4143045,0.049760893],"study_design_scores_gemma":[0.0024608613,0.00033834422,0.04346259,0.00028626205,0.00050364994,0.00199652,0.00010139,0.00023421383,0.65981513,0.01134127,0.27885538,0.00060440047],"about_ca_topic_score_codex":0.0002851795,"about_ca_topic_score_gemma":0.0000025192876,"teacher_disagreement_score":0.25414038,"about_ca_system_score_codex":0.00012622935,"about_ca_system_score_gemma":0.0005145637,"threshold_uncertainty_score":0.99987864},"labels":[],"label_agreement":null},{"id":"W4408809005","doi":"10.1080/15548627.2025.2477443","title":"HMBOX1 reverses autophagy mediated 5-fluorouracil resistance through promoting HACE1-induced ubiquitination and degradation of ATG5 in colorectal cancer","year":2025,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Natural Science Foundation of China","keywords":"ATG5; Autophagy; Biology; Colorectal cancer; Cancer research; Downregulation and upregulation; Mouse model of colorectal and intestinal cancer; Cancer; Small interfering RNA; Ubiquitin; Transfection; Cell culture; Gene; Genetics; Apoptosis","score_opus":0.016156670204069305,"score_gpt":0.31384578089505394,"score_spread":0.29768911069098464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408809005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99030006,0.003977491,0.00007556717,0.001531787,0.00021176269,0.00056127284,0.000024592213,0.00010715096,0.003210325],"genre_scores_gemma":[0.9961304,0.00066989555,0.00071379996,0.00043228813,0.00005026352,0.00013053662,0.00006341233,0.000023495137,0.0017859179],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983092,0.00012204408,0.00055603415,0.0004134859,0.00029846604,0.00030079254],"domain_scores_gemma":[0.9990201,0.00021979744,0.00025527913,0.00024178458,0.00019326093,0.00006980468],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030633292,0.00022119995,0.00048655563,0.00020413422,0.000093266804,0.000018205978,0.0001249427,0.00018652262,0.00012805413],"category_scores_gemma":[0.000554056,0.00021411745,0.000073553776,0.00068405183,0.0001014544,0.00028595107,0.000065906286,0.00021506047,0.0000045183233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001462753,0.0007758421,0.020415714,0.0014226836,0.0004050636,0.00019055369,0.004106392,0.000009995204,0.9060879,0.009857395,0.00095312134,0.054312587],"study_design_scores_gemma":[0.0034323495,0.00016472022,0.29272857,0.00085439865,0.00012239807,0.0000066513844,0.00023290246,0.001103074,0.69824994,0.0022501713,0.0006618191,0.00019298686],"about_ca_topic_score_codex":0.00037408675,"about_ca_topic_score_gemma":0.00033418884,"teacher_disagreement_score":0.27231288,"about_ca_system_score_codex":0.00021411762,"about_ca_system_score_gemma":0.0004098031,"threshold_uncertainty_score":0.87314564},"labels":[],"label_agreement":null},{"id":"W4409069741","doi":"10.1186/s12964-025-02142-x","title":"DNM1L-mediated fission governs mitophagy &amp; mitochondrial biogenesis during myogenic differentiation","year":2025,"lang":"en","type":"article","venue":"Cell Communication and Signaling","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"DNM1L; Mitophagy; Mitochondrial fission; Cell biology; Myogenesis; Mitochondrial biogenesis; Biology; PPARGC1A; C2C12; Mitochondrion; Myocyte; Genetics; Coactivator; Apoptosis","score_opus":0.011002272285129185,"score_gpt":0.2611366033634251,"score_spread":0.2501343310782959,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409069741","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98880816,0.008279951,0.0008767312,0.00040817296,0.00012454916,0.00027498076,0.000010208938,0.00009220071,0.0011250338],"genre_scores_gemma":[0.99380785,0.0023166805,0.0006570955,0.00031695794,0.00006401745,0.000026329597,0.0003378492,0.000015985694,0.0024572292],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990794,0.00012473809,0.00028963562,0.00020523283,0.00014947906,0.00015151687],"domain_scores_gemma":[0.9990112,0.00015125972,0.00011057855,0.00055055984,0.00007558856,0.00010078669],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008512073,0.00014065912,0.00020669149,0.00013523617,0.00031120004,0.0000402879,0.00014382954,0.000121858124,0.00027103742],"category_scores_gemma":[0.000055593413,0.00013125759,0.00009905858,0.00021936631,0.00004791803,0.00006846002,0.00008979215,0.00015383323,0.000024914048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030062743,0.00019435615,0.0063978103,0.00012876099,0.000085742395,0.0000016120678,0.0003558889,0.000010526562,0.99111605,0.000112638736,0.00033056003,0.0009654199],"study_design_scores_gemma":[0.0058787046,0.00005215217,0.10631756,0.0004497094,0.0003045659,0.000005172281,0.00031289,0.00121026,0.8765609,0.0005841378,0.0080143,0.00030965055],"about_ca_topic_score_codex":0.00003376249,"about_ca_topic_score_gemma":0.000007894744,"teacher_disagreement_score":0.11455516,"about_ca_system_score_codex":0.00005968405,"about_ca_system_score_gemma":0.000055664583,"threshold_uncertainty_score":0.5352529},"labels":[],"label_agreement":null},{"id":"W4409105943","doi":"10.3389/fimmu.2025.1528230","title":"The role of autophagy in cancer: from molecular mechanism to therapeutic window","year":2025,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Autophagy; Mechanism (biology); Carcinogenesis; Cell biology; Cancer; Tumor microenvironment; Biology; Cancer cell; Cancer research; Apoptosis; Biochemistry; Genetics","score_opus":0.00976051120940024,"score_gpt":0.3042801010785604,"score_spread":0.29451958986916016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409105943","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00034399613,0.99467343,0.00041356552,0.00015710082,0.0021744308,0.0017459152,0.00006453374,0.000024715484,0.00040232574],"genre_scores_gemma":[0.00037642726,0.99744815,0.0004441635,0.00031524102,0.00006661466,0.0008648913,0.00005458619,0.000044608347,0.00038530913],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978069,0.00039043673,0.00077985745,0.00043545096,0.0001617928,0.0004255319],"domain_scores_gemma":[0.99863625,0.00018810328,0.0002489184,0.0008382726,0.000040150964,0.000048312733],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021227324,0.00036687255,0.002099582,0.0005552167,0.0000386952,0.000008053491,0.0005877494,0.0005350876,0.000055436496],"category_scores_gemma":[0.00006794571,0.00026837637,0.00036720064,0.0006500236,0.00012980109,0.00001991111,0.00012944486,0.0006208191,0.000009853353],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018581642,0.000105627994,0.00006152418,0.0006419083,0.0012456864,0.000083193125,0.00014239206,0.0000013610711,0.00015821507,0.0024146594,0.0001518202,0.9948078],"study_design_scores_gemma":[0.0012347245,0.00019452791,0.00029417517,0.010005929,0.00081506727,0.0000071015397,0.00024099727,0.000015272453,0.0014827647,0.022907078,0.96250767,0.00029468338],"about_ca_topic_score_codex":0.0004905308,"about_ca_topic_score_gemma":0.000034755365,"teacher_disagreement_score":0.9945131,"about_ca_system_score_codex":0.00035966674,"about_ca_system_score_gemma":0.0010478838,"threshold_uncertainty_score":0.9999768},"labels":[],"label_agreement":null},{"id":"W4409180723","doi":"10.1002/2211-5463.70014","title":"A non‐fluorescent immunohistochemistry method for measuring autophagy flux using <scp>MAP1LC3</scp>/<scp>LC3</scp> and <scp>SQSTM1</scp> as core markers","year":2025,"lang":"en","type":"article","venue":"FEBS Open Bio","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Agencia Estatal de Investigación; National Institutes of Health; European Commission; National Institute of General Medical Sciences; CancerCare Manitoba Foundation","keywords":"Autophagy; Autophagosome; Cell biology; Organelle; Immunohistochemistry; Fluorescence microscope; Flux (metallurgy); Lysosome; Biology; Chemistry; Pathology; Fluorescence; Medicine; Biochemistry; Enzyme; Apoptosis","score_opus":0.03464058138287885,"score_gpt":0.35146573908200424,"score_spread":0.3168251576991254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409180723","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9462576,0.010959299,0.004301242,0.0002031788,0.00095299445,0.004151548,0.00014732027,0.00026516218,0.032761667],"genre_scores_gemma":[0.73708385,0.0014201717,0.08700454,0.010276302,0.0015446381,0.0018697801,0.001179795,0.00074449717,0.15887645],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9954269,0.00014622102,0.0010244248,0.0014475075,0.00063284696,0.0013220906],"domain_scores_gemma":[0.9955947,0.0013753645,0.00050590857,0.00140228,0.00043042703,0.00069133646],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013791037,0.00090700213,0.0014122226,0.00037517716,0.0007901981,0.00041739226,0.0010961972,0.0006301987,0.00007246877],"category_scores_gemma":[0.0021644018,0.0008865911,0.0005254241,0.0007644767,0.00032660598,0.00037571855,0.0008084959,0.0007015413,0.000069744434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045074144,0.0012151959,0.007943858,0.0023277604,0.0033892738,0.00043992625,0.0028243305,0.000057621903,0.818895,0.0009997778,0.15088168,0.010574824],"study_design_scores_gemma":[0.012831466,0.0006005376,0.022142464,0.002253007,0.0016865634,0.0002672491,0.004463008,0.0063640107,0.7952786,0.0023357503,0.15151742,0.0002598915],"about_ca_topic_score_codex":0.0004402394,"about_ca_topic_score_gemma":0.000007878291,"teacher_disagreement_score":0.20917377,"about_ca_system_score_codex":0.00055596523,"about_ca_system_score_gemma":0.0012088238,"threshold_uncertainty_score":0.9993585},"labels":[],"label_agreement":null},{"id":"W4409637247","doi":"10.1158/1538-7445.am2025-6908","title":"Abstract 6908: Autophagy disruption via PIKfyve inhibition as a novel strategy to enhance immunotherapy responses in multiple myeloma","year":2025,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Systems, Applications & Products in Data Processing (Canada); Princess Margaret Cancer Centre","funders":"","keywords":"Autophagy; Multiple myeloma; Immunotherapy; Cancer immunotherapy; Cancer research; Biology; Cancer; Medicine; Immunology; Internal medicine; Biochemistry; Apoptosis","score_opus":0.0593214463097121,"score_gpt":0.4571631983761023,"score_spread":0.3978417520663902,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409637247","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99134123,0.0029006654,0.00054815604,0.0016899615,0.00012294191,0.0012641245,0.00003080944,0.00007267415,0.002029411],"genre_scores_gemma":[0.99224627,0.0007705822,0.000080321806,0.00095396175,0.00016422101,0.00083112426,0.000028569682,0.000035358375,0.004889615],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99774486,0.00013830968,0.0003823747,0.00053624675,0.0005977198,0.0006005011],"domain_scores_gemma":[0.99865067,0.0003104604,0.00004843632,0.0005009093,0.0003029729,0.00018654103],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008501168,0.00019351723,0.00030430598,0.00072391593,0.00017715538,0.00006147976,0.0001679796,0.00016605025,0.0008793566],"category_scores_gemma":[0.00024361006,0.00018330578,0.00009162258,0.0012027231,0.00015603214,0.00016692966,0.000058751233,0.0005980884,0.00019182326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007376514,0.00047627196,0.0012016896,0.00012058957,0.00006537404,0.00012693703,0.0005201873,0.000060204282,0.89376897,0.00035748444,0.00054182904,0.09538396],"study_design_scores_gemma":[0.0024918844,0.0005021223,0.34589225,0.0007069871,0.0000072883727,0.000006374711,0.0002554172,0.00014264917,0.6457006,0.0012393286,0.00289071,0.00016443092],"about_ca_topic_score_codex":0.0020413005,"about_ca_topic_score_gemma":0.00040585798,"teacher_disagreement_score":0.34469056,"about_ca_system_score_codex":0.0006945641,"about_ca_system_score_gemma":0.0010514192,"threshold_uncertainty_score":0.96283376},"labels":[],"label_agreement":null},{"id":"W4409697108","doi":"10.1038/s41537-025-00617-x","title":"Aberrant aging-associated p62 autophagic cascade in biopsied olfactory neuronal cells from patients with psychosis","year":2025,"lang":"en","type":"article","venue":"Schizophrenia","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"CIHR Skin Research Training Centre; National Institute of Mental Health; Canadian Institutes of Health Research; U.S. Department of Health and Human Services; National Institutes of Health; Government of Canada; National Alliance for Research on Schizophrenia and Depression","keywords":"Psychosis; Autophagy; Neuroscience; Olfaction; Olfactory memory; Psychology; Medicine; Biology; Psychiatry; Olfactory bulb; Central nervous system; Genetics; Apoptosis","score_opus":0.008989935558217317,"score_gpt":0.24076619087398077,"score_spread":0.23177625531576346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409697108","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99685144,0.0005832618,0.000016216529,0.00040944671,0.00056112034,0.00048422525,0.00014241216,0.00015215449,0.00079973304],"genre_scores_gemma":[0.99705946,0.000044782686,0.00022564956,0.0015778672,0.00007067394,0.000035859066,0.000221023,0.000039864735,0.00072479626],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99823475,0.00009348623,0.00036866637,0.000518658,0.00037937926,0.00040506557],"domain_scores_gemma":[0.9991039,0.000088137625,0.000121595695,0.00043955137,0.00007411225,0.00017267835],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008353892,0.00030511338,0.00045560248,0.0002815145,0.00008505152,0.000029056866,0.00018503737,0.00016937581,0.00042256722],"category_scores_gemma":[0.000028962306,0.00024950242,0.00012318464,0.0005663403,0.00008988856,0.00009416572,0.000038344253,0.00043106693,0.00010084222],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0134227285,0.0054861433,0.9095206,0.00014010792,0.0017713542,0.000408711,0.0010901735,0.000046498084,0.0363562,0.00031305503,0.010099733,0.021344699],"study_design_scores_gemma":[0.013210619,0.00017478292,0.9713305,0.00032357345,0.00016510593,4.3421412e-7,0.000014827803,0.00012898467,0.013248055,0.00050405296,0.0006644913,0.00023455702],"about_ca_topic_score_codex":0.00031820303,"about_ca_topic_score_gemma":0.0001508311,"teacher_disagreement_score":0.06180992,"about_ca_system_score_codex":0.00014709473,"about_ca_system_score_gemma":0.00020688013,"threshold_uncertainty_score":0.9999957},"labels":[],"label_agreement":null},{"id":"W4409836698","doi":"10.1038/s41420-025-02490-0","title":"Sex and region-specific disruption of autophagy and mitophagy in Alzheimer’s disease: linking cellular dysfunction to cognitive decline","year":2025,"lang":"en","type":"article","venue":"Cell Death Discovery","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; St. Boniface Hospital; University of Manitoba","funders":"National Institute of General Medical Sciences; National Institute of Neurological Disorders and Stroke; Research Manitoba; National Institutes of Health; Alzheimer's Association","keywords":"Mitophagy; Autophagy; Hippocampus; Autophagosome; Mitochondrion; Biology; Neuroscience; Cognition; Disease; Cognitive decline; Psychology; Medicine; Cell biology; Internal medicine; Genetics; Apoptosis; Dementia","score_opus":0.02089618700189576,"score_gpt":0.2811905943137314,"score_spread":0.2602944073118356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409836698","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95560366,0.035715293,0.0068893777,0.00018076196,0.00020432494,0.0006187274,0.000021601507,0.000031593067,0.0007346871],"genre_scores_gemma":[0.99555105,0.002476169,0.000094781084,0.0007501292,0.00011778345,0.00004454552,0.000091287104,0.000022575112,0.00085169554],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987223,0.000064486,0.0003534831,0.00045312228,0.00018428013,0.00022232438],"domain_scores_gemma":[0.9992977,0.00014867788,0.00008707899,0.00024228175,0.000057269794,0.00016702381],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013421195,0.00020997814,0.00037884634,0.00028163113,0.000069152244,0.000042671025,0.000054449065,0.00010062224,0.00001295015],"category_scores_gemma":[0.000029376455,0.00019705907,0.00007960915,0.0002773284,0.000093973715,0.00020822069,0.00009820337,0.00014546455,0.000004238059],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008147662,0.0020166321,0.7973052,0.0014473265,0.00050643,0.0012439098,0.0016763505,0.000078870165,0.08933019,0.0059823445,0.00038499082,0.09188005],"study_design_scores_gemma":[0.0043022647,0.00027581057,0.872869,0.0012078261,0.00044581093,0.000008770396,0.0004009246,0.0005375997,0.11571576,0.0028123364,0.0011380597,0.00028584397],"about_ca_topic_score_codex":0.000025661899,"about_ca_topic_score_gemma":0.0000035170458,"teacher_disagreement_score":0.09159421,"about_ca_system_score_codex":0.000041825402,"about_ca_system_score_gemma":0.00010126155,"threshold_uncertainty_score":0.80358356},"labels":[],"label_agreement":null},{"id":"W4410122593","doi":"10.1096/fj.202401781r","title":"Reduced Palmitoylation of <scp>SQSTM1</scp> /p62 in Huntington Disease Is Associated With Impaired Autophagy","year":2025,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Children's Hospital; University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Royal Society","keywords":"Palmitoylation; Autophagy; Sequestosome 1; Cell biology; Chemistry; ULK1; Flux (metallurgy); Lysosome; Biology; Biochemistry; Apoptosis; Enzyme; Phosphorylation","score_opus":0.011418131635590762,"score_gpt":0.26579004647672083,"score_spread":0.2543719148411301,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410122593","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99599016,0.0008944227,0.00009673537,0.0011507838,0.00015512537,0.00030354384,0.000015468435,0.000037343485,0.0013564215],"genre_scores_gemma":[0.99672544,0.00011244751,0.000040596584,0.0011903115,0.00011404455,0.000009131364,0.000019445182,0.000019920806,0.0017686483],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99854845,0.00017058365,0.00043332367,0.00016355969,0.0003876187,0.00029646026],"domain_scores_gemma":[0.9988013,0.00023069314,0.00033004608,0.00029275267,0.00017195757,0.00017328175],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005288278,0.00016853603,0.0003380181,0.0002343562,0.00015333951,0.000031235202,0.00017049625,0.00007939875,0.00008260314],"category_scores_gemma":[0.0004375003,0.00010804355,0.00015810195,0.0005639969,0.00010239771,0.00010625006,0.000026336587,0.0003937008,0.0000057713028],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003260716,0.0029101358,0.52977204,0.0002908218,0.0028590788,0.00087996153,0.008303946,0.0006209988,0.42326838,0.0010274879,0.012785209,0.01402123],"study_design_scores_gemma":[0.0046532014,0.00021849372,0.7760272,0.00092870067,0.00040742222,0.000022206043,0.00050439587,0.0013611492,0.21371694,0.0019650583,0.00013266425,0.000062559295],"about_ca_topic_score_codex":0.000020051217,"about_ca_topic_score_gemma":0.0000043096625,"teacher_disagreement_score":0.24625519,"about_ca_system_score_codex":0.00013566307,"about_ca_system_score_gemma":0.0005527209,"threshold_uncertainty_score":0.44058877},"labels":[],"label_agreement":null},{"id":"W4410754994","doi":"10.1038/s41589-025-01913-4","title":"Tegavivint triggers TECR-dependent nonapoptotic cancer cell death","year":2025,"lang":"en","type":"article","venue":"Nature Chemical Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Cancer Institute; Government of Canada; U.S. Department of Health and Human Services; National Institutes of Health; National Science Foundation","keywords":"Programmed cell death; Biology; Cell biology; Computational biology; Apoptosis; Genetics","score_opus":0.006993592436016473,"score_gpt":0.3239077677677645,"score_spread":0.316914175331748,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410754994","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95569706,0.021607915,0.000051467843,0.002042264,0.00058284454,0.00029603942,0.000030928288,0.000106798245,0.019584674],"genre_scores_gemma":[0.9904697,0.00080923666,0.00018732475,0.006269025,0.00023591325,0.00005035027,0.00006965803,0.000012874137,0.0018959433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990155,0.000023712477,0.00019339818,0.0003706941,0.000093185176,0.0003034889],"domain_scores_gemma":[0.99937993,0.00009660919,0.00004489076,0.00027763692,0.00007212813,0.00012879766],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006344234,0.00017863578,0.00033798118,0.000053958614,0.000033445365,0.000005020774,0.00016205135,0.0007853773,0.0007019976],"category_scores_gemma":[0.00007213649,0.00012979339,0.00014611422,0.00014248175,0.00008883132,0.000016947864,0.000056152778,0.0007179683,0.000028226706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044273425,0.00030344483,0.0067991815,0.000090587,0.00019924408,0.000028258411,0.00002266499,3.403271e-7,0.97741675,0.0030115696,0.0036250716,0.00806018],"study_design_scores_gemma":[0.0019148531,0.00007771456,0.0023067342,0.000060067283,0.0001580084,0.000008486564,0.000018042601,0.000017872208,0.966854,0.0022165773,0.02621895,0.00014873206],"about_ca_topic_score_codex":0.00004777077,"about_ca_topic_score_gemma":0.0000033782424,"teacher_disagreement_score":0.03477261,"about_ca_system_score_codex":0.00022034917,"about_ca_system_score_gemma":0.00020728951,"threshold_uncertainty_score":0.76863813},"labels":[],"label_agreement":null},{"id":"W4410951360","doi":"10.3390/biom15060797","title":"Tuning Autophagy for Improved Liver Transplant Outcomes: Insights from Experimental Models","year":2025,"lang":"en","type":"review","venue":"Biomolecules","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"BC Children's Hospital","keywords":"Autophagy; Economic shortage; Liver transplantation; Xenotransplantation; Immune modulation; Intensive care medicine; Medicine; Organ transplantation; Scarcity; Reperfusion injury; Transplantation; Immune system; Immunology; Biology; Ischemia; Surgery; Internal medicine; Economics; Apoptosis","score_opus":0.052749940221262386,"score_gpt":0.3544711850511601,"score_spread":0.3017212448298977,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410951360","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000921628,0.98899806,0.007038913,0.000020106207,0.00035775514,0.0020059594,0.0009123575,0.00015676148,0.00041794093],"genre_scores_gemma":[0.0008262351,0.9933334,0.0015840498,0.00047340847,0.0001808395,0.0006228814,0.0020607798,0.00008814865,0.0008302596],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982563,0.00007003978,0.00056923256,0.0006306611,0.00016764451,0.00030608673],"domain_scores_gemma":[0.99885345,0.0002159896,0.00018067165,0.00052291795,0.000043879973,0.00018307372],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000035280744,0.00059938274,0.001869097,0.00024228424,0.0000999163,0.00003509073,0.00026194513,0.00042023466,0.00007007342],"category_scores_gemma":[0.000013132505,0.00043154074,0.0011768785,0.00014767103,0.00008789727,0.00006771254,0.000045931145,0.00017253857,0.000020203435],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040518882,0.0013621156,7.643849e-7,0.024941301,0.0053755674,0.0006832231,0.0010016462,4.171699e-7,0.0036576304,0.0058435225,0.00084697886,0.95588166],"study_design_scores_gemma":[0.0054839742,0.0005651258,0.0000068771888,0.037672654,0.007945934,0.000039278184,0.00011291115,0.0026388154,0.009043316,0.0011059977,0.9339044,0.0014806937],"about_ca_topic_score_codex":0.0000813541,"about_ca_topic_score_gemma":0.0000031852965,"teacher_disagreement_score":0.95440096,"about_ca_system_score_codex":0.00012492664,"about_ca_system_score_gemma":0.0004932378,"threshold_uncertainty_score":0.9998136},"labels":[],"label_agreement":null},{"id":"W4411176523","doi":"10.1172/jci186065","title":"TNF-α impairs platelet function by inhibiting autophagy and disrupting metabolism via syntaxin 17 downregulation","year":2025,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Bioinformatics Solutions (Canada)","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Heart, Lung, and Blood Institute; University of Colorado School of Medicine, Anschutz Medical Campus; Anschutz Medical Campus, University of Colorado; Uniformed Services University of the Health Sciences","keywords":"Downregulation and upregulation; Autophagy; Cell biology; Function (biology); Metabolism; Chemistry; Platelet; Tumor necrosis factor alpha; Biology; Immunology; Biochemistry; Gene; Apoptosis","score_opus":0.027540655677919582,"score_gpt":0.35635126729433847,"score_spread":0.3288106116164189,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411176523","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98789054,0.0018769862,0.0069485647,0.0022804479,0.0004886301,0.00018244922,0.0000028398986,0.00003358119,0.00029596966],"genre_scores_gemma":[0.99512076,0.00017552241,0.0014235107,0.0022458672,0.0006607868,0.0000032148703,0.00002523557,0.000013423225,0.00033164938],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.997646,0.00020526952,0.0014947838,0.00019178049,0.0003085102,0.00015370395],"domain_scores_gemma":[0.9979533,0.0004553414,0.0009728674,0.000115076225,0.00024555772,0.00025785132],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017750054,0.0001457518,0.000529972,0.00016989134,0.000115739225,0.000043969794,0.000053742344,0.00021455468,0.00004292638],"category_scores_gemma":[0.0010990864,0.000118321725,0.00020591679,0.00024515289,0.00016453743,0.00039014494,0.00002424179,0.00048184922,0.0000032048065],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034782272,0.0006377199,0.06068221,0.00039089666,0.001432095,0.000102123064,0.0005844996,0.00027209404,0.27796805,0.0038192878,0.01728166,0.63335115],"study_design_scores_gemma":[0.007988037,0.0008086132,0.8649052,0.001024441,0.0010012999,0.00014692968,0.00021402045,0.010167653,0.078416325,0.029883338,0.0051837326,0.00026043542],"about_ca_topic_score_codex":0.000009470185,"about_ca_topic_score_gemma":0.0000010051242,"teacher_disagreement_score":0.80422294,"about_ca_system_score_codex":0.000039672417,"about_ca_system_score_gemma":0.000196142,"threshold_uncertainty_score":0.48250198},"labels":[],"label_agreement":null},{"id":"W4411183962","doi":"10.1080/27694127.2025.2514232","title":"Autophagy-enhancing strategies to promote intestinal viral resistance and mucosal barrier function in SARS-CoV-2 infection","year":2025,"lang":"en","type":"article","venue":"Autophagy Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; ZonMw; Amsterdam University Medical Centers","keywords":"Autophagy; Barrier function; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Function (biology); Virology; Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Microbiology; Biology; Medicine; Cell biology; Disease; Pathology; Infectious disease (medical specialty); Outbreak","score_opus":0.010199714598793826,"score_gpt":0.29861306092396994,"score_spread":0.2884133463251761,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411183962","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987364,0.0010924436,0.0031777674,0.00026772227,0.0007052532,0.0007639166,0.0000016918996,0.00029236317,0.0063348752],"genre_scores_gemma":[0.99518746,0.000030513036,0.0007585014,0.0010961923,0.00012738477,0.00012494062,0.000017205288,0.00003051381,0.0026272822],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99787533,0.000065544686,0.0007110025,0.0006739092,0.00027706666,0.00039711987],"domain_scores_gemma":[0.9990564,0.000041488307,0.00017988667,0.00046662707,0.00013525676,0.000120313634],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048183274,0.00029532044,0.00044637776,0.00041432533,0.00014569989,0.0000948298,0.000048939477,0.00017001318,0.000043088472],"category_scores_gemma":[0.00026746767,0.00028771212,0.000097299664,0.000582293,0.00008450065,0.00037932195,0.00006714583,0.00034068103,0.000012346079],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001579689,0.00051472767,0.054441635,0.00071821705,0.00027000718,0.005619514,0.0010605287,0.00004562977,0.91200906,0.0043452755,0.0019479656,0.017447762],"study_design_scores_gemma":[0.001173562,0.0003793289,0.56167036,0.0007639072,0.0001491329,0.000425514,0.00007688733,0.00026147548,0.41405568,0.012948039,0.00778242,0.00031372442],"about_ca_topic_score_codex":0.00025100991,"about_ca_topic_score_gemma":0.00045863824,"teacher_disagreement_score":0.50722873,"about_ca_system_score_codex":0.00019052869,"about_ca_system_score_gemma":0.00053770415,"threshold_uncertainty_score":0.9999575},"labels":[],"label_agreement":null},{"id":"W4411393326","doi":"10.1016/j.celrep.2025.115870","title":"The evolutionarily conserved PRP4K-CHMP4B/vps32 splicing circuit regulates autophagy","year":2025,"lang":"en","type":"article","venue":"Cell Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trent University; Dalhousie University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; University of Tsukuba; Universität zu Köln; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Autophagy; Cell biology; Biology; Dictyostelium; Dictyostelium discoideum; RNA splicing; Autophagosome; Lysosome; Alternative splicing; BAG3; ATG8; Gene; Exon; Genetics; RNA; Biochemistry","score_opus":0.010723437632266034,"score_gpt":0.2548496984679757,"score_spread":0.2441262608357097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411393326","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9004516,0.013514858,0.00018850526,0.001102642,0.0009926195,0.0006417751,0.0000017802622,0.000235731,0.082870506],"genre_scores_gemma":[0.9337971,0.00020255087,0.000059069247,0.0009850161,0.0001390045,0.00004752881,0.000021477215,0.000022526729,0.0647257],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998383,0.000046182337,0.00054106116,0.00039335992,0.00028688277,0.0003495354],"domain_scores_gemma":[0.99839437,0.00018426806,0.0002168752,0.00090308685,0.00016471824,0.00013670005],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000385541,0.00018974535,0.00028621644,0.00008027028,0.00040695758,0.00004254635,0.00010434656,0.00012856213,0.0001775864],"category_scores_gemma":[0.0001679706,0.0001383671,0.00019291633,0.0002581023,0.00017715072,0.000054242973,0.00005596419,0.00020083893,0.000032202726],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010689582,0.0020806645,0.20471005,0.001553771,0.0020841456,0.019835945,0.0012969495,0.00016931887,0.45375067,0.04346003,0.22478385,0.045205653],"study_design_scores_gemma":[0.0017351094,0.00014480327,0.40059978,0.00042472064,0.00045056303,0.00089127367,0.00021759565,0.00055794633,0.3220101,0.041604575,0.2309714,0.0003921353],"about_ca_topic_score_codex":0.0000735271,"about_ca_topic_score_gemma":0.000006135514,"teacher_disagreement_score":0.19588973,"about_ca_system_score_codex":0.00011861273,"about_ca_system_score_gemma":0.0005514193,"threshold_uncertainty_score":0.5642447},"labels":[],"label_agreement":null},{"id":"W4411429700","doi":"10.3390/ijms26125827","title":"Dysregulation of Inositol Polyphosphate 5-Phosphatase OCRL in Alzheimer’s Disease: Implications for Autophagy Dysfunction","year":2025,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Aging; Institute of Genetics; National Institutes of Health; Fondation Médicale Reine Elisabeth; Fondation pour la Recherche sur Alzheimer; Koning Boudewijnstichting; Université de Liège; University of Pennsylvania; China Scholarship Council; Centre Hospitalier Universitaire de Rennes; Fonds De La Recherche Scientifique - FNRS; Centre Hospitalier Régional Universitaire de Montpellier; Rush University; Fondation pour l'Aide à la Recherche sur la Sclérose en Plaques; Association France Parkinson; University of Pittsburgh; University of Miami","keywords":"Autophagy; Polyphosphate; Inositol; Disease; Alzheimer's disease; Alkaline phosphatase; Phosphatase; Biochemistry; Medicine; Chemistry; Biology; Internal medicine; Enzyme; Phosphate; Receptor","score_opus":0.01999659992784754,"score_gpt":0.3513333386581853,"score_spread":0.33133673873033775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411429700","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9441207,0.018493295,0.026307778,0.0093460465,0.0009733509,0.00037879,0.000050973034,0.000010733168,0.0003183445],"genre_scores_gemma":[0.9971736,0.00013854502,0.0018837998,0.00067875284,0.00005590577,0.000013521109,0.000017604823,0.0000044595813,0.00003382775],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"observational","domain_scores_codex":[0.9989119,0.000026181186,0.0004586294,0.00013948337,0.0003565288,0.00010723809],"domain_scores_gemma":[0.99896306,0.00007163812,0.00030235003,0.00010820662,0.00047903214,0.00007573934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000316593,0.000081265585,0.0001654896,0.00043310464,0.000044355347,0.000027182547,0.00028187296,0.000034115717,0.0000228124],"category_scores_gemma":[0.000120070916,0.00006928813,0.00015158497,0.0003301784,0.00013520685,0.00020821046,0.000025453659,0.000062131236,7.3818927e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0050015147,0.002313533,0.20522961,0.000104574676,0.0018507031,0.00024930915,0.00034248494,0.0072387094,0.13884342,0.39431998,0.002451051,0.24205512],"study_design_scores_gemma":[0.0030591136,0.00030563597,0.73270094,0.0003848923,0.00027705298,0.000033789445,0.00006585982,0.0022542102,0.23058027,0.028695937,0.0015337467,0.000108514156],"about_ca_topic_score_codex":0.000015372865,"about_ca_topic_score_gemma":0.0000019434694,"teacher_disagreement_score":0.52747136,"about_ca_system_score_codex":0.00006141729,"about_ca_system_score_gemma":0.0005061172,"threshold_uncertainty_score":0.2825488},"labels":[],"label_agreement":null},{"id":"W4411489147","doi":"10.1096/fj.202500568rr","title":"Dolutegravir Inhibits Autophagy In Vitro in a Mouse Blood–Brain Barrier Model","year":2025,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Ontario HIV Treatment Network","keywords":"Autophagy; Dolutegravir; Blood–brain barrier; Pharmacology; Endoplasmic reticulum; Raltegravir; Tolerability; Unfolded protein response; In vitro; Medicine; Chemistry; Cancer research; Immunology; Human immunodeficiency virus (HIV); Antiretroviral therapy; Apoptosis; Biochemistry; Internal medicine; Viral load; Adverse effect","score_opus":0.011914767481222579,"score_gpt":0.2766299977267222,"score_spread":0.26471523024549964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411489147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99264437,0.001765292,0.00040245146,0.0028700712,0.00010672099,0.00026855274,0.000017141901,0.00002919647,0.0018961745],"genre_scores_gemma":[0.98586595,0.00017910656,0.00029018894,0.005485264,0.000114656745,0.000018497138,0.0000056576287,0.000020685466,0.008019976],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99856776,0.00015604214,0.00043479778,0.0001844012,0.00026693338,0.000390074],"domain_scores_gemma":[0.9992918,0.0001002146,0.00008404452,0.00031683163,0.000044849363,0.00016230354],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007262858,0.00018259579,0.00032735776,0.00038401588,0.00011250915,0.000040343613,0.00022536494,0.00010995011,0.00011548895],"category_scores_gemma":[0.00012237822,0.00012272497,0.00015218853,0.00040942032,0.000086330954,0.00011068153,0.000049890918,0.0008672018,0.000016287751],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011378549,0.00042946442,0.0011202255,0.000024197405,0.00012348361,0.0005659275,0.0010914033,0.0010268174,0.98928666,0.00080853637,0.0008557127,0.0035297375],"study_design_scores_gemma":[0.0078,0.000085818974,0.00287694,0.00024268945,0.000093576455,0.00023971306,0.00029691702,0.021484306,0.95695317,0.009573562,0.00018644061,0.00016689833],"about_ca_topic_score_codex":0.000034286833,"about_ca_topic_score_gemma":0.000018490484,"teacher_disagreement_score":0.0323335,"about_ca_system_score_codex":0.00012261863,"about_ca_system_score_gemma":0.00052471424,"threshold_uncertainty_score":0.50045794},"labels":[],"label_agreement":null},{"id":"W4411612137","doi":"10.3934/molsci.2025012","title":"The master energy sensor AMPK-1α regulates the expression of various autophagic and mitochondrial respiratory elements in T cell memory","year":2025,"lang":"en","type":"article","venue":"AIMS molecular science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Autophagy; AMPK; Cell biology; Mitochondrion; Cell; Chemistry; Biology; Apoptosis; Biochemistry; Protein kinase A","score_opus":0.006583751860267981,"score_gpt":0.25246202886010527,"score_spread":0.24587827699983728,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411612137","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934198,0.0033562202,0.00035341494,0.00046597063,0.00023046184,0.00025175104,0.0000011370071,0.000012622786,0.0019086003],"genre_scores_gemma":[0.99689806,0.000057555684,0.00026124026,0.0017111427,0.000022749484,0.000021358039,5.980267e-7,0.000007005749,0.0010203151],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987053,0.00010127433,0.00025872872,0.00029882893,0.00039030405,0.00024556406],"domain_scores_gemma":[0.99914634,0.00008477714,0.000090348876,0.000544982,0.00006940068,0.00006416066],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039095824,0.00011088928,0.00014055116,0.000113654525,0.00020220673,0.000038782953,0.00030777563,0.000047005782,0.000011463509],"category_scores_gemma":[0.00007127595,0.000062403145,0.000047668225,0.0003712531,0.0005582249,0.00006708515,0.00015192849,0.000103086626,0.0000014162856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010315346,0.000056056462,0.0004645261,0.000013889525,0.000008199287,0.000041259627,0.00019639896,0.000022666432,0.9947054,0.0010153612,0.00011205685,0.0032610712],"study_design_scores_gemma":[0.0010995725,0.000091060436,0.006411522,0.00008398355,0.00002245848,0.0000030989943,0.00015428985,0.0004352269,0.98828477,0.0014542752,0.0018934712,0.00006627307],"about_ca_topic_score_codex":0.000037706748,"about_ca_topic_score_gemma":0.0000051953766,"teacher_disagreement_score":0.0064205932,"about_ca_system_score_codex":0.000037747166,"about_ca_system_score_gemma":0.0002607423,"threshold_uncertainty_score":0.25447264},"labels":[],"label_agreement":null},{"id":"W4411712603","doi":"10.1083/jcb.202408025","title":"A substrate-interacting region of Parkin directs ubiquitination of the mitochondrial GTPase Miro1","year":2025,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Parkin; Mitophagy; Ubiquitin; Cell biology; PINK1; Ubiquitin ligase; Mitochondrion; Biology; Autophagy; Parkinson's disease; Genetics; Gene; Disease; Medicine","score_opus":0.012687915147086266,"score_gpt":0.2901377023898542,"score_spread":0.2774497872427679,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411712603","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99494517,0.0011209723,0.00017965522,0.0009388093,0.0006628216,0.00012922696,0.0000015055112,0.00000267575,0.0020191441],"genre_scores_gemma":[0.9990311,0.0002594382,0.000054477714,0.00020192085,0.00015121175,8.190435e-7,0.0000010625987,0.0000041761637,0.0002957506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99910766,0.00026911343,0.0004078603,0.000050031787,0.000074921314,0.000090395784],"domain_scores_gemma":[0.9985776,0.00037638086,0.0006625613,0.000167633,0.00019178794,0.000024068657],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028352748,0.000068143956,0.0002437708,0.000075316384,0.00003580616,0.0000017969871,0.00016425802,0.0000661426,0.000027398764],"category_scores_gemma":[0.00017798487,0.000033683486,0.0001490429,0.00013028085,0.00011791942,0.000025397976,0.000023515773,0.00019069407,6.510485e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020727168,0.00016511147,0.001380209,0.000061679166,0.00013422713,0.0000085229985,0.00048715595,0.0000124581475,0.9929621,0.00028063342,0.0002711811,0.0021640079],"study_design_scores_gemma":[0.0015376946,0.00036957642,0.009363767,0.00026734074,0.0002395297,0.00006137215,0.00025144767,0.00004227127,0.9851025,0.0015828814,0.0011518309,0.000029806817],"about_ca_topic_score_codex":0.00001845837,"about_ca_topic_score_gemma":0.000004164617,"teacher_disagreement_score":0.007983558,"about_ca_system_score_codex":0.000022490758,"about_ca_system_score_gemma":0.00014473835,"threshold_uncertainty_score":0.13735726},"labels":[],"label_agreement":null},{"id":"W4411995202","doi":"10.3390/cells14131016","title":"Post-Translational Modification of p62: Roles and Regulations in Autophagy","year":2025,"lang":"en","type":"review","venue":"Cells","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Key Research and Development Program of China; Hubei University; Hubei University of Technology; National Natural Science Foundation of China","keywords":"Autophagy; Posttranslational modification; Cell biology; Computational biology; Neuroscience; Biology; Biochemistry; Apoptosis","score_opus":0.02624083185783628,"score_gpt":0.3449076870545694,"score_spread":0.31866685519673316,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411995202","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004106879,0.9974132,0.00006404798,0.00005802054,0.00005626234,0.0006022994,0.00012292313,0.000015563835,0.001256955],"genre_scores_gemma":[0.0012508766,0.99629325,0.00022191532,0.000036847137,0.00004466627,0.000040007228,0.00044009608,0.000013192187,0.0016591472],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991605,0.000050758495,0.0003932821,0.00019456203,0.00011601123,0.00008483851],"domain_scores_gemma":[0.9994039,0.00014416919,0.0001265468,0.00022595136,0.000056107627,0.00004331266],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008517982,0.00014199078,0.00064600597,0.00026560624,0.000019002486,0.000004789128,0.000056761324,0.00017489391,0.00010015704],"category_scores_gemma":[0.000016359467,0.00012254337,0.00015297094,0.00020660553,0.000049465234,0.00002941312,0.000010460395,0.00011713445,0.000008643962],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020609148,0.00016589627,0.000018363835,0.017183298,0.00011555265,0.0000068535933,0.00014086344,0.000007660373,0.0001772911,0.0027851528,0.00008558108,0.97929287],"study_design_scores_gemma":[0.0020617025,0.0001320478,0.0077386037,0.040601205,0.0025950777,0.000023978502,0.000045609184,0.00033596018,0.0014563993,0.002578817,0.9418863,0.00054430263],"about_ca_topic_score_codex":0.0000078009425,"about_ca_topic_score_gemma":0.000002506792,"teacher_disagreement_score":0.97874856,"about_ca_system_score_codex":0.000022150864,"about_ca_system_score_gemma":0.0003857295,"threshold_uncertainty_score":0.49971735},"labels":[],"label_agreement":null},{"id":"W4412110230","doi":"10.1080/15548627.2025.2531025","title":"Activation of endogenous PRKN by structural derepression is linked to increased turnover of the E3 ubiquitin ligase","year":2025,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; McGill University Health Centre; Structural Genomics Consortium; McGill University; Health Canada; Montreal Neurological Institute and Hospital","funders":"Robert and Arlene Kogod Center on Aging; Congressionally Directed Medical Research Programs; National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Institutes of Health; University of Dundee; Ted Nash Long Life Foundation; Florida Department of Health; Michael J. Fox Foundation for Parkinson's Research; U.S. Department of Defense","keywords":"Mitophagy; Biology; Ubiquitin ligase; Ubiquitin; PINK1; Autophagy; Cell biology; Derepression; Mitochondrion; Deubiquitinating enzyme; Biochemistry; Gene; Psychological repression; Apoptosis","score_opus":0.012935527534316931,"score_gpt":0.2833326808428972,"score_spread":0.2703971533085803,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412110230","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99639744,0.0006014738,0.0000806908,0.0006709932,0.00012414515,0.00060110283,0.000053581884,0.00003364289,0.0014369433],"genre_scores_gemma":[0.9963199,0.000011478416,0.000094340605,0.0027324008,0.00004718627,0.000021267404,0.000025291916,0.00001447613,0.0007336788],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989223,0.000063578824,0.0003522549,0.00021833659,0.00027228138,0.00017123764],"domain_scores_gemma":[0.9989971,0.00009810303,0.00017635683,0.0005160781,0.00013058956,0.00008176173],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008994899,0.00014363948,0.0003081943,0.00008711672,0.000066752866,0.000006102245,0.00017891002,0.00011018949,0.0003361317],"category_scores_gemma":[0.00015909702,0.00009763996,0.00014196869,0.00032933633,0.00006512355,0.0000559692,0.000081083715,0.00012815895,0.000004571579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004535867,0.00013268628,0.002356205,0.00011884319,0.00012770909,0.0000037770305,0.000588701,0.000007275745,0.9860039,0.00031244455,0.0024250613,0.0074698455],"study_design_scores_gemma":[0.0014716127,0.00010725038,0.10823406,0.00024986741,0.00008981648,0.0000044671724,0.00003683321,0.00011785496,0.8880724,0.00084763975,0.0007008701,0.000067336005],"about_ca_topic_score_codex":0.00026458252,"about_ca_topic_score_gemma":0.0000017879687,"teacher_disagreement_score":0.10587786,"about_ca_system_score_codex":0.00005170065,"about_ca_system_score_gemma":0.00021441947,"threshold_uncertainty_score":0.3981642},"labels":[],"label_agreement":null},{"id":"W4412493309","doi":"10.1038/s41598-025-11584-9","title":"CAMKKβ supports growth and viability of epithelial ovarian cancer in vitro and in vivo","year":2025,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ovarian Cancer Canada; Occupational Cancer Research Centre; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"AMPK; Spheroid; Cancer research; Biology; Cell biology; Protein kinase A; Autophagy; Ovarian cancer; Viability assay; Kinase; Cell; Cell culture; Apoptosis; Cancer; Genetics","score_opus":0.006511675792501918,"score_gpt":0.27494557004230125,"score_spread":0.26843389424979935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412493309","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964856,0.00064179924,0.0000068362106,0.00036854675,0.0010316104,0.00039269673,0.000012702135,0.000011208499,0.0010489983],"genre_scores_gemma":[0.99901515,0.00003915608,0.00006549834,0.0000717502,0.000016344862,0.000024700243,0.0000061896326,0.0000049139035,0.00075631187],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870485,0.000035080546,0.00042705666,0.00047131558,0.00018572494,0.00017595396],"domain_scores_gemma":[0.9993811,0.000029903389,0.000103079285,0.00034915557,0.000054986725,0.0000817689],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008059527,0.00009148924,0.00027544436,0.00025971027,0.000041252657,0.000021874406,0.000029174389,0.00006067657,0.00013165144],"category_scores_gemma":[0.000111467205,0.00007870292,0.000033744753,0.00043355013,0.00030308467,0.00007159789,0.00004195385,0.00008579438,1.5501277e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024915644,0.0001913017,0.53317976,0.0002491124,0.000020896603,0.00072342495,0.0005064191,0.0000014944318,0.4617998,0.00006796196,0.00023858725,0.0027720602],"study_design_scores_gemma":[0.00076977565,0.000016459575,0.42874858,0.00014224673,0.000030112278,0.000047985766,0.0000684648,0.00007207915,0.55893344,0.010367787,0.00072553934,0.000077509925],"about_ca_topic_score_codex":0.0006930169,"about_ca_topic_score_gemma":0.00016874624,"teacher_disagreement_score":0.10443118,"about_ca_system_score_codex":0.000038558544,"about_ca_system_score_gemma":0.000351143,"threshold_uncertainty_score":0.3209412},"labels":[],"label_agreement":null},{"id":"W4412521733","doi":"10.1186/s13046-025-03473-w","title":"Targeting autophagy and plasminogen activator inhibitor-1 increases survival and remodels the tumor microenvironment in glioblastoma","year":2025,"lang":"en","type":"article","venue":"Journal of Experimental & Clinical Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Stony Brook University","keywords":"Autophagy; Cancer research; Glioma; Tumor microenvironment; Biology; Plasminogen activator; Plasminogen activator inhibitor-1; Bioluminescence imaging; Tumor progression; Transfection; Apoptosis; Cell culture; Cancer; Luciferase; Endocrinology","score_opus":0.06515821627675437,"score_gpt":0.4564839897240276,"score_spread":0.3913257734472732,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412521733","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9690106,0.029121198,0.0000028700538,0.0011998896,0.00018348712,0.00033320056,0.0000058729543,0.000004519319,0.00013834829],"genre_scores_gemma":[0.9955998,0.0032406833,0.000077717385,0.0005066151,0.00041003324,0.000025443811,4.936212e-7,0.000015767328,0.00012346507],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975962,0.00050159957,0.00075152237,0.00026056156,0.0005762777,0.00031383487],"domain_scores_gemma":[0.9984517,0.00088998245,0.00016163652,0.00016632788,0.00008074129,0.00024960036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021582916,0.00013964169,0.00044979525,0.00017662733,0.00014997677,0.00004374157,0.00015875675,0.00008061265,0.00015690344],"category_scores_gemma":[0.00032634215,0.000091742666,0.00010206404,0.00019975915,0.0005524233,0.0001271145,0.00023807543,0.00083733525,0.0000017249938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.021726122,0.0031547754,0.15166534,0.00013729061,0.000593886,0.0009970284,0.00083616027,0.000015359392,0.80344087,0.000316265,0.0042029936,0.0129139135],"study_design_scores_gemma":[0.011672745,0.0032979527,0.21694885,0.0011003008,0.000079039724,0.0001356589,0.0054490473,0.00038527348,0.7559611,0.00039581725,0.00435972,0.00021449212],"about_ca_topic_score_codex":0.00015688041,"about_ca_topic_score_gemma":0.00000846475,"teacher_disagreement_score":0.06528351,"about_ca_system_score_codex":0.00025385956,"about_ca_system_score_gemma":0.00038995472,"threshold_uncertainty_score":0.37411574},"labels":[],"label_agreement":null},{"id":"W4412559316","doi":"10.1016/j.cbpc.2025.110298","title":"EGCG attenuates BPA -induced male reproductive toxicity by regulating the blood-testis barrier by suppressing autophagy via AMPK/AKT/mTOR signaling pathway","year":2025,"lang":"en","type":"article","venue":"Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Key Research and Development Program of China; Priority Academic Program Development of Jiangsu Higher Education Institutions","keywords":"Autophagy; PI3K/AKT/mTOR pathway; AMPK; Protein kinase B; Cell biology; Signal transduction; Chemistry; Endocrinology; Biology; Apoptosis; Phosphorylation; Biochemistry; Protein kinase A","score_opus":0.023587860534089213,"score_gpt":0.3217041289436579,"score_spread":0.2981162684095687,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412559316","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888172,0.0062661273,0.000068856774,0.0023587225,0.0007186247,0.00074163184,0.00012268405,0.000119768,0.00078637776],"genre_scores_gemma":[0.9909121,0.000057592293,0.00011433313,0.0051631387,0.000745018,0.00033136937,0.0002683264,0.000027143498,0.0023809737],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965287,0.0006324838,0.0006477363,0.0012998629,0.00013367951,0.0007575478],"domain_scores_gemma":[0.9976395,0.000919196,0.0004018937,0.00058748445,0.00022855822,0.0002234169],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00036694715,0.00057095964,0.0010796646,0.000072871364,0.000817239,0.00002629983,0.00040946936,0.00055587554,0.0010278921],"category_scores_gemma":[0.00016019843,0.0004648983,0.00018367873,0.00033291368,0.0016040191,0.00011004705,0.00032261614,0.00087849656,0.000017446115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009964696,0.00070721377,0.000934626,0.000092977665,0.0011679468,0.000030308434,0.000298131,0.000014583609,0.95731,0.00005003249,0.038053304,0.00034436234],"study_design_scores_gemma":[0.0026665165,0.00044413778,0.0012697977,0.00004888001,0.000619762,0.00013155547,0.00019728803,0.00052891497,0.98844075,0.00073897885,0.0045427587,0.0003706774],"about_ca_topic_score_codex":0.000010092918,"about_ca_topic_score_gemma":7.1919345e-7,"teacher_disagreement_score":0.033510543,"about_ca_system_score_codex":0.000086405336,"about_ca_system_score_gemma":0.00026143662,"threshold_uncertainty_score":0.9998853},"labels":[],"label_agreement":null},{"id":"W4412857142","doi":"10.1016/j.ijpharm.2025.126010","title":"Liposomal delivery of a disulfiram metabolite drives copper-mediated tumor immunity","year":2025,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Children's Hospital; University of British Columbia; Spinal Cord Injury BC","funders":"BC Cancer Foundation; University of British Columbia; Canadian Institutes of Health Research; NanoMedicines Innovation Network; Mitacs; Canadian Cancer Society","keywords":"Disulfiram; Liposome; Metabolite; Pharmacology; Immunity; Chemistry; Copper; Medicine; Immune system; Immunology; Biochemistry","score_opus":0.02085100438108894,"score_gpt":0.36916771403205556,"score_spread":0.3483167096509666,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412857142","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989597,0.006305561,0.00020662823,0.0011237419,0.0013063584,0.00010443945,0.000064992375,0.00001357723,0.0012776754],"genre_scores_gemma":[0.9947643,0.002292826,0.00046007385,0.001958372,0.00027911196,0.0000016518477,0.000018571698,0.000010815409,0.00021424415],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985826,0.0000736089,0.0006145137,0.000080512735,0.0005189582,0.0001297895],"domain_scores_gemma":[0.99811584,0.00018415305,0.0003943747,0.000119793825,0.0010580708,0.00012777546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024090646,0.00012326904,0.00032401417,0.00033889018,0.000029130739,0.000017630666,0.00034943124,0.00004356938,0.00017236492],"category_scores_gemma":[0.00016795043,0.00010211652,0.0002652023,0.00017526433,0.000121489174,0.00014745335,0.00007174094,0.00034376298,0.000007909053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0066263,0.002857033,0.08567313,0.00016127032,0.007981152,0.0011689821,0.00088343944,0.00013213219,0.8585147,0.0027657538,0.0013037031,0.031932373],"study_design_scores_gemma":[0.009880047,0.0002472268,0.10614429,0.0005621654,0.0010176103,0.00040103903,0.00036285148,0.0018675142,0.8292063,0.0009356829,0.049204603,0.00017066812],"about_ca_topic_score_codex":0.0000081815215,"about_ca_topic_score_gemma":4.5615778e-7,"teacher_disagreement_score":0.0479009,"about_ca_system_score_codex":0.000081339116,"about_ca_system_score_gemma":0.00041933096,"threshold_uncertainty_score":0.4164191},"labels":[],"label_agreement":null},{"id":"W4412942479","doi":"10.53941/hm.2025.100024","title":"Autophagy: A Major Regulatory Factor in Glucose Metabolism","year":2025,"lang":"en","type":"article","venue":"Health and Metabolism","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Tellabs (Canada)","funders":"","keywords":"Autophagy; Carbohydrate metabolism; Cell biology; Metabolism; Chemistry; Biology; Biochemistry; Apoptosis","score_opus":0.012827439123228345,"score_gpt":0.31429039476228,"score_spread":0.3014629556390516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412942479","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.79266584,0.20189603,0.000041265004,0.003039836,0.00055610563,0.0005903064,0.000022664088,0.00009314244,0.0010948301],"genre_scores_gemma":[0.9598136,0.008872778,0.0005299433,0.027162677,0.0002684393,0.00008831226,0.000025867072,0.000027974933,0.0032104084],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99831474,0.000111974485,0.00045913243,0.0003889552,0.00021395794,0.0005112605],"domain_scores_gemma":[0.9988473,0.000044884262,0.00009295905,0.00040137593,0.000047825124,0.0005656685],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002627781,0.00022773203,0.00072179636,0.0003883947,0.00011857513,0.000018799732,0.00008265381,0.00013520829,0.00013692045],"category_scores_gemma":[0.000077908204,0.00019177492,0.00010896715,0.00041169816,0.000078939156,0.00010045757,0.000042698623,0.000286333,0.000019859861],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002330833,0.0016256458,0.014951848,0.0024154405,0.00062868884,0.0002558707,0.005571555,0.0000013957848,0.011465645,0.17849779,0.012015092,0.7702402],"study_design_scores_gemma":[0.00513217,0.00003731953,0.69987875,0.00013694182,0.00006737065,0.000010886793,0.00013302595,0.00004770846,0.0042672413,0.0024178212,0.28772435,0.00014638773],"about_ca_topic_score_codex":0.00021858724,"about_ca_topic_score_gemma":0.000019957773,"teacher_disagreement_score":0.7700938,"about_ca_system_score_codex":0.000051905776,"about_ca_system_score_gemma":0.000972149,"threshold_uncertainty_score":0.78203547},"labels":[],"label_agreement":null},{"id":"W4413111625","doi":"10.1016/j.cbd.2025.101602","title":"Deciphering multi-organ protein regulatory strategies in the Asian frog, Pelophylax nigromaculatus during hibernation to elucidate energy homeostasis maintenance mechanisms","year":2025,"lang":"en","type":"article","venue":"Comparative Biochemistry and Physiology Part D Genomics and Proteomics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Hebei Normal University; Hebei Normal University of Science and Technology","keywords":"Glycogenolysis; Hibernation (computing); Biology; Energy homeostasis; Glycogen; Amphibian; Cell biology; Energy metabolism; Proteomics; Organism; Ecology; Biochemistry; Endocrinology; Receptor; Genetics","score_opus":0.013904587749762264,"score_gpt":0.2698928745671362,"score_spread":0.2559882868173739,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413111625","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960829,0.0010855651,0.0017079441,0.00031434285,0.00004152059,0.00056512,0.000025017142,0.00001736624,0.00016024332],"genre_scores_gemma":[0.99643207,0.00019698981,0.0025944759,0.00030411966,0.000066912675,0.00017776054,0.00004675477,0.000010279103,0.00017065958],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99897933,0.000066199296,0.00024678538,0.00040614523,0.00006273001,0.00023882197],"domain_scores_gemma":[0.9994875,0.000019205143,0.00008986108,0.00026779965,0.00005126949,0.00008435987],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001224014,0.0002218744,0.0003310435,0.000056134577,0.00019091992,0.00004530601,0.00012675917,0.00013146903,0.000005893751],"category_scores_gemma":[0.000010823333,0.00017977708,0.000045667268,0.00015675781,0.00012603468,0.000050662227,0.00008005767,0.00017911762,0.0000011069415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006282967,0.0000799089,0.00015757653,0.00011955451,0.0000936701,0.0000093858,0.0008417573,0.000054874134,0.9945106,0.003047049,0.000017134087,0.00044020603],"study_design_scores_gemma":[0.0014744734,0.00010298549,0.06322491,0.00013988394,0.000027136131,0.00001409217,0.0017729757,0.0005831802,0.92490035,0.007212124,0.00032611185,0.00022180515],"about_ca_topic_score_codex":0.000016240183,"about_ca_topic_score_gemma":0.0000131464085,"teacher_disagreement_score":0.06961026,"about_ca_system_score_codex":0.00006264638,"about_ca_system_score_gemma":0.00011276435,"threshold_uncertainty_score":0.73310965},"labels":[],"label_agreement":null},{"id":"W4413306935","doi":"10.1186/s12929-025-01153-7","title":"Activation of mitophagy and proteasomal degradation confers resistance to developmental defects in postnatal skeletal muscle","year":2025,"lang":"en","type":"article","venue":"Journal of Biomedical Science","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mitophagy; Cell biology; Skeletal muscle; Degradation (telecommunications); Autophagy; Chemistry; Biology; Endocrinology; Apoptosis; Biochemistry; Computer science","score_opus":0.00879462654102039,"score_gpt":0.2884368855118647,"score_spread":0.2796422589708443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413306935","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972103,0.00014623597,0.0009419123,0.0012071732,0.000089976544,0.00017675682,0.000001458235,0.000003004293,0.00022313787],"genre_scores_gemma":[0.9966275,0.000015467218,0.0029913073,0.00027735005,0.00002677684,0.0000023300722,0.0000010123746,0.0000019703207,0.000056267378],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989018,0.000020105244,0.00030413724,0.000118408614,0.00052033504,0.00013523335],"domain_scores_gemma":[0.99947095,0.000047976602,0.00011880099,0.00005102485,0.00013158354,0.00017966559],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051153393,0.000057760237,0.00015690803,0.00040503795,0.000046409506,0.000011556989,0.00011146488,0.000039142735,0.000016792526],"category_scores_gemma":[0.0004930111,0.000044026656,0.000029029252,0.0008709641,0.00035363281,0.00019237239,0.000032692424,0.00010620722,6.2094887e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036136087,0.0002567967,0.0073607117,0.00007592887,0.000017028231,0.0000707977,0.00031011348,6.1370525e-7,0.9549961,0.0004446417,0.00016709359,0.03593882],"study_design_scores_gemma":[0.0013227058,0.00025764643,0.75629574,0.0004975194,0.000008991622,0.00003283289,0.00024035954,0.00003054685,0.24025123,0.00018702682,0.00082941767,0.000045991645],"about_ca_topic_score_codex":0.00000771833,"about_ca_topic_score_gemma":0.0000031708587,"teacher_disagreement_score":0.74893504,"about_ca_system_score_codex":0.00014037274,"about_ca_system_score_gemma":0.00086221966,"threshold_uncertainty_score":0.1795355},"labels":[],"label_agreement":null},{"id":"W4413330953","doi":"10.1042/bst20253050","title":"Canonical and alternate mechanisms that regulate ubiquitylation by the E3 ligase parkin","year":2025,"lang":"en","type":"article","venue":"Biochemical Society Transactions","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Parkin; Mitophagy; Ubiquitin ligase; Ubiquitin; Cell biology; PINK1; Mitochondrion; Biology; Phosphorylation; Autophagy; Cytosol; Chemistry; Biochemistry; Enzyme; Parkinson's disease; Gene","score_opus":0.009157288275908407,"score_gpt":0.2646495293230278,"score_spread":0.25549224104711943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413330953","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90612274,0.0025440748,0.076951146,0.013294985,0.00012659984,0.00036764718,0.000050052313,0.00011669786,0.00042606643],"genre_scores_gemma":[0.994118,0.0007188655,0.0004468662,0.0026425803,0.000035226734,0.000043678705,0.000033142405,0.000010635548,0.0019510426],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929285,0.000021587311,0.00013784388,0.00022424146,0.00014916666,0.00017432477],"domain_scores_gemma":[0.99956846,0.00006454157,0.000028349614,0.00020154657,0.000026476668,0.0001106316],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009844192,0.00011876155,0.00014116334,0.000010400114,0.00020957823,0.000023752205,0.00006999953,0.00015445829,0.000098815195],"category_scores_gemma":[0.000005005541,0.00008563954,0.0002098396,0.00013442445,0.00015320166,0.00003888532,0.000007771201,0.00022446287,0.0000031595994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018882439,0.00033277608,0.00010521379,0.00008214022,0.00065922213,0.0000030379344,0.00037569227,0.0000032808618,0.9661417,0.0012320017,0.019312305,0.011563808],"study_design_scores_gemma":[0.0013054858,0.000039685186,0.0017034026,0.00005850568,0.0003753733,0.000016346941,0.00013724752,0.0010958862,0.984059,0.0043841437,0.0067083314,0.00011662105],"about_ca_topic_score_codex":0.000053399577,"about_ca_topic_score_gemma":0.0000013630936,"teacher_disagreement_score":0.08799523,"about_ca_system_score_codex":0.000060456132,"about_ca_system_score_gemma":0.00008258598,"threshold_uncertainty_score":0.34922794},"labels":[],"label_agreement":null},{"id":"W4413366356","doi":"10.1038/s41598-025-08204-x","title":"Nfe2l1 dysfunction alters Parkinson’s disease-related gene expression and impairs neuronal differentiation under ubiquitin stress in neuronal differentiated P19 Cells","year":2025,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Narodowym Centrum Nauki","keywords":"Proteostasis; Gene knockdown; Proteasome; Cell biology; Biology; Regulator; Neurodegeneration; Ubiquitin; Downregulation and upregulation; Cellular differentiation; Gene; Disease; Medicine; Internal medicine; Genetics","score_opus":0.009119363922406185,"score_gpt":0.24146199388523046,"score_spread":0.2323426299628243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413366356","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992401,0.0004273871,0.00037476837,0.0003095789,0.0055967467,0.00063966116,0.000015045608,0.00012117676,0.00011460277],"genre_scores_gemma":[0.99656916,0.00005754347,0.000028374248,0.00017547999,0.00004879241,0.000047380294,0.00058193615,0.00002559985,0.0024657364],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9972093,0.00014709693,0.00067783904,0.0010169224,0.0005642299,0.00038457187],"domain_scores_gemma":[0.99868464,0.000047883164,0.00026775265,0.0006097438,0.000097364515,0.00029262993],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030842188,0.00026953802,0.00031115924,0.00046863948,0.00025821116,0.00016355788,0.000077978286,0.00011513559,0.0003307918],"category_scores_gemma":[0.00004717467,0.00023433991,0.00013590828,0.000497952,0.00018950953,0.00019004893,0.00009633467,0.00023894316,0.0000057870366],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055872294,0.0010278381,0.25045517,0.00021208219,0.00010054002,0.00059202395,0.00022662763,0.00060089317,0.74065286,0.00007266934,0.004009854,0.0014907495],"study_design_scores_gemma":[0.0013679713,0.000050975927,0.7875994,0.0002993906,0.00014202637,0.000018209534,0.000060496313,0.002729655,0.20418637,0.00293373,0.0004252055,0.00018661686],"about_ca_topic_score_codex":0.000019594683,"about_ca_topic_score_gemma":0.000010496927,"teacher_disagreement_score":0.5371442,"about_ca_system_score_codex":0.00010583798,"about_ca_system_score_gemma":0.00022059168,"threshold_uncertainty_score":0.9556104},"labels":[],"label_agreement":null},{"id":"W4413375155","doi":"10.1083/jcb.202405138","title":"Identification of organelle-specific autophagy regulators from tandem CRISPR screens","year":2025,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Autophagy; Cell biology; BAG3; Biology; Organelle; ULK1; Activator (genetics); Cytosol; Kinase; Protein kinase A; Biochemistry; Gene; Apoptosis; Enzyme","score_opus":0.011229765917466931,"score_gpt":0.2792460989532139,"score_spread":0.26801633303574696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413375155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9864762,0.00802713,0.0034879313,0.0005064315,0.00044226515,0.00010964931,0.000008496636,0.000009014153,0.00093287864],"genre_scores_gemma":[0.9966977,0.0018706773,0.00010191838,0.00032077916,0.00019026795,5.423661e-7,0.0000068977315,0.000008016407,0.0008031844],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891764,0.00016751452,0.0006000879,0.0000874686,0.00010954623,0.00011776392],"domain_scores_gemma":[0.9987091,0.00021544228,0.0004891764,0.0003099846,0.00022389929,0.000052401963],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004703635,0.000093740986,0.00032925818,0.00013014872,0.000051987106,0.0000037586562,0.00022482693,0.000112756425,0.0003034521],"category_scores_gemma":[0.00004510985,0.000056829704,0.0001271126,0.00018690174,0.00017011492,0.000028894812,0.000026156105,0.00019218243,0.000013810272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004979725,0.0001227286,0.0010212064,0.000011471248,0.0001788402,0.000007879695,0.00023760929,0.000010478714,0.99359834,0.00075767265,0.0015409547,0.002014837],"study_design_scores_gemma":[0.0012427185,0.00020533032,0.040589202,0.00004483998,0.0002266026,0.0000147293495,0.0002947961,0.000047280184,0.9452072,0.0069751088,0.005106392,0.00004581823],"about_ca_topic_score_codex":0.000011771846,"about_ca_topic_score_gemma":8.382617e-7,"teacher_disagreement_score":0.048391167,"about_ca_system_score_codex":0.000036186513,"about_ca_system_score_gemma":0.00013715899,"threshold_uncertainty_score":0.33225876},"labels":[],"label_agreement":null},{"id":"W4413500350","doi":"10.1128/msphere.00308-25","title":"Unc-51-like kinase 1 (ULK1) regulates bacterial ubiquitylation and p62 recruitment during xenophagic clearance of <i>Listeria monocyt</i> ogenes","year":2025,"lang":"en","type":"article","venue":"mSphere","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"ULK1; Autophagy; Cell biology; Intracellular parasite; Biology; Intracellular; Signal transducing adaptor protein; Ubiquitin; Listeria monocytogenes; Protein kinase A; Kinase; Phosphorylation; Microbiology; Bacteria; Biochemistry; Genetics; AMPK; Gene","score_opus":0.022649136713078867,"score_gpt":0.29486478660202375,"score_spread":0.27221564988894487,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413500350","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923494,0.005209474,0.0000199508,0.00023388067,0.00035483003,0.00056671904,0.000017739647,0.00006296571,0.0011850809],"genre_scores_gemma":[0.9956198,0.00038385784,0.00033684404,0.00023886535,0.00013645965,0.00004624267,0.000033514647,0.000020243646,0.0031842133],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990463,0.000047443224,0.00029847477,0.00028308204,0.0001382542,0.00018641402],"domain_scores_gemma":[0.9993895,0.000025162282,0.00010699663,0.00033454315,0.00006254957,0.00008123875],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008636837,0.00017015522,0.00032115457,0.000045399847,0.00008868212,0.000023844948,0.000072878254,0.00010444113,0.00041047137],"category_scores_gemma":[0.000013433866,0.00015571204,0.00007405304,0.00016081714,0.000081605474,0.0000928058,0.00006105841,0.00007142556,0.000009246309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004928528,0.00042239347,0.0116811525,0.0012982615,0.00037398376,0.00009706177,0.0006289058,0.00004160653,0.9432293,0.0006188569,0.00071863126,0.03596129],"study_design_scores_gemma":[0.00472868,0.00026902504,0.35806772,0.00067507185,0.00021371832,0.000018613091,0.00017089205,0.00015080611,0.62644094,0.001202741,0.007846824,0.00021499695],"about_ca_topic_score_codex":0.000037651178,"about_ca_topic_score_gemma":0.000014934895,"teacher_disagreement_score":0.34638655,"about_ca_system_score_codex":0.00005877058,"about_ca_system_score_gemma":0.00006769994,"threshold_uncertainty_score":0.63497525},"labels":[],"label_agreement":null},{"id":"W4413599198","doi":"10.1080/27694127.2025.2547975","title":"Sequestering sequestosome 1 via S-acylation in autophagy, Huntington disease, and beyond","year":2025,"lang":"en","type":"article","venue":"Autophagy Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Sequestosome 1; Neurodegeneration; Autophagy; Cell biology; Protein aggregation; Proteostasis; Biology; Huntington's disease; Chemistry; Biochemistry; Medicine; Disease; Internal medicine; Apoptosis","score_opus":0.008135600404960123,"score_gpt":0.2818925959365832,"score_spread":0.2737569955316231,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413599198","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866043,0.0033706906,0.00040485334,0.00057757803,0.0005207078,0.0006563592,0.0000030522906,0.0002814759,0.0075809974],"genre_scores_gemma":[0.9947154,0.00015700322,0.00040193286,0.0014861212,0.00011926774,0.000085905565,0.000068024136,0.00003814906,0.0029282256],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99791294,0.000056968936,0.0007096468,0.0006431596,0.00028146463,0.0003958355],"domain_scores_gemma":[0.99879944,0.000054925298,0.00020747993,0.0006133094,0.00007646638,0.00024836895],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00035085256,0.00028959563,0.00047057826,0.00038387513,0.00011232179,0.00005607897,0.000065410764,0.00015237546,0.00012768168],"category_scores_gemma":[0.00011843191,0.00028987136,0.00011061259,0.000440656,0.00011371599,0.00030813293,0.00010585217,0.00024384179,0.0000079499005],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00095703936,0.001211583,0.7471517,0.001639714,0.0006228055,0.018582165,0.0011143078,0.00017478738,0.13553731,0.0077127507,0.0007238741,0.08457199],"study_design_scores_gemma":[0.0012781906,0.000094559044,0.9413944,0.00042137897,0.00019369059,0.0002711981,0.000027271444,0.0018550749,0.035775077,0.014968916,0.0033939818,0.00032625566],"about_ca_topic_score_codex":0.0000793915,"about_ca_topic_score_gemma":0.000008832171,"teacher_disagreement_score":0.19424273,"about_ca_system_score_codex":0.00015656001,"about_ca_system_score_gemma":0.00035318983,"threshold_uncertainty_score":0.99995536},"labels":[],"label_agreement":null},{"id":"W4413769988","doi":"10.1080/15548627.2025.2551672","title":"<i>Salmonella</i> Typhimurium exploits the reticulophagy/ERphagy receptor RETREG1 to promote infection","year":2025,"lang":"fr","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Salmonella; Exploit; Salmonella infection; Microbiology; Virology; Bacteria; Genetics","score_opus":0.010262135534907287,"score_gpt":0.29020010035120963,"score_spread":0.27993796481630234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413769988","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.77418697,0.107916944,0.0016716819,0.04151804,0.03213225,0.0040183,0.00012148982,0.0007869012,0.0376474],"genre_scores_gemma":[0.7696353,0.006318445,0.00052603363,0.015860343,0.0037639672,0.00045339554,0.000089470974,0.00016992519,0.2031831],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99511564,0.0004974559,0.0010310095,0.0011757794,0.00072403194,0.0014560766],"domain_scores_gemma":[0.9965559,0.00032920289,0.00026274493,0.0017759261,0.0004302202,0.00064597395],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00097224896,0.0008100528,0.00090100284,0.0003993668,0.0006140332,0.0001748282,0.00060716,0.0006654598,0.0037874691],"category_scores_gemma":[0.0006231598,0.0006639113,0.00052862987,0.0023996264,0.00044404596,0.00031993,0.0003302713,0.0010059996,0.006649009],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018144926,0.002687696,0.002156118,0.0015815471,0.0024069818,0.0006881457,0.004352908,0.00027099502,0.069690555,0.043419927,0.5233545,0.34757617],"study_design_scores_gemma":[0.0023459091,0.0008484592,0.024506256,0.0017841498,0.0007639025,0.00006582084,0.00015975299,0.000498935,0.24165687,0.0028884693,0.72386444,0.00061700575],"about_ca_topic_score_codex":0.00041563332,"about_ca_topic_score_gemma":0.000028432574,"teacher_disagreement_score":0.34695917,"about_ca_system_score_codex":0.00064912124,"about_ca_system_score_gemma":0.0008005929,"threshold_uncertainty_score":0.9995812},"labels":[],"label_agreement":null},{"id":"W4414152276","doi":"10.1016/bs.ircmb.2025.08.002","title":"Epigenetic regulation of autophagy in cancer: A double-edged sword in tumor progression and therapy resistance","year":2025,"lang":"en","type":"book-chapter","venue":"International review of cell and molecular biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; University of Manitoba","funders":"Organization of Chinese Americans","keywords":"Autophagy; Epigenetics; Crosstalk; Tumor progression; Tumor microenvironment; DNA methylation; Histone; Epigenetic therapy; Precision medicine","score_opus":0.012288110775763758,"score_gpt":0.33747278676986947,"score_spread":0.3251846759941057,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414152276","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03659635,0.91379833,0.00006940044,0.0006567501,0.00012015204,0.0009741619,0.00003393067,0.0000054495404,0.047745474],"genre_scores_gemma":[0.2659374,0.7209832,0.00034153523,0.0008454147,0.000031166343,0.00007918446,0.00013920957,0.000017219549,0.011625698],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999037,0.000034922403,0.00048439045,0.00025049938,0.000115604365,0.00007753393],"domain_scores_gemma":[0.9993747,0.000033564942,0.00030482872,0.0001419345,0.00011535915,0.000029639617],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014777706,0.00015256128,0.00052852684,0.0001921351,0.000006019905,0.0000016307664,0.000080017955,0.000120978235,0.00011075678],"category_scores_gemma":[0.000016545258,0.0001240088,0.000079985024,0.00003971156,0.00011128826,0.000010517212,0.000035234483,0.000118818556,3.1346738e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00535419,0.0005719056,0.0030909267,0.028653352,0.00065405713,0.00026517417,0.00014548018,0.0000026570044,0.26694292,0.20768182,0.00032640775,0.48631114],"study_design_scores_gemma":[0.017241783,0.0012292534,0.02619973,0.17408343,0.00040654853,0.000033685235,0.0000073143347,0.000107080625,0.36853918,0.0736192,0.33766884,0.0008639606],"about_ca_topic_score_codex":0.000013898759,"about_ca_topic_score_gemma":0.000011433739,"teacher_disagreement_score":0.48544717,"about_ca_system_score_codex":0.00002989663,"about_ca_system_score_gemma":0.00014382409,"threshold_uncertainty_score":0.5056932},"labels":[],"label_agreement":null},{"id":"W4414187897","doi":"10.1016/j.jbc.2025.110716","title":"The lipid phosphatase INPP4B controls pancreatic cancer cell migration and invasion by regulating fibronectin exocytosis","year":2025,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canada Foundation for Innovation; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Cell migration; Fibronectin; Focal adhesion; Lysosome; Motility; Receptor; Cell; Cell growth; Sorting nexin","score_opus":0.013390731507819423,"score_gpt":0.26928758017804866,"score_spread":0.2558968486702292,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414187897","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95878845,0.039399527,0.00003166544,0.001288652,0.000044287113,0.0000835481,0.000012281079,0.000007904262,0.00034366793],"genre_scores_gemma":[0.98786825,0.010968232,0.00006600444,0.0004672419,0.00015956633,0.000007772667,0.000012425916,0.000003484174,0.0004470387],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993258,0.000034149143,0.0003153153,0.00010396054,0.00010335267,0.000117391595],"domain_scores_gemma":[0.9992038,0.0002975046,0.00023776131,0.00009999107,0.00007280343,0.00008811902],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002141617,0.00009612723,0.00023693236,0.0000064347028,0.000112442554,0.000023663155,0.00006884042,0.000113200345,0.00008548224],"category_scores_gemma":[0.00022924894,0.000049905597,0.0000836968,0.0000600609,0.00007676408,0.00003778674,0.00002221592,0.00017472333,3.7827394e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00092714024,0.00009378924,0.013604805,0.00007590644,0.00009370928,0.000008543419,0.000021587577,0.0000016309406,0.9709651,0.000006564245,0.0043960093,0.009805204],"study_design_scores_gemma":[0.0016450284,0.0001643689,0.0076362384,0.00024119459,0.00011006813,0.000023047454,0.00017682882,0.000088851026,0.98321027,0.00016500591,0.006478478,0.000060608258],"about_ca_topic_score_codex":0.000019513474,"about_ca_topic_score_gemma":0.0000013003547,"teacher_disagreement_score":0.029079767,"about_ca_system_score_codex":0.00006600374,"about_ca_system_score_gemma":0.00007187023,"threshold_uncertainty_score":0.20350912},"labels":[],"label_agreement":null},{"id":"W4414192454","doi":"10.1101/2025.09.09.675181","title":"Isolation of functional lysosomes from skeletal muscle","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Skeletal muscle; Lysosome; Organelle; Mitochondrion; Autophagy; Function (biology); Myocyte; Enzyme","score_opus":0.014004920321313282,"score_gpt":0.2358536227035656,"score_spread":0.22184870238225232,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414192454","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882421,0.0032688412,0.005351351,0.00021901874,0.001338361,0.00052974763,0.000737526,0.0002479952,0.00006505063],"genre_scores_gemma":[0.9955479,0.0002760894,0.0029390128,0.0003374077,0.0007308417,0.000080380414,0.000005192324,0.000047860285,0.000035300196],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981351,0.000065652464,0.00050030055,0.00063449587,0.00041063371,0.00025382522],"domain_scores_gemma":[0.99800676,0.00008362556,0.00032899762,0.00096672657,0.00043815144,0.0001757611],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016332704,0.00035998132,0.00060551515,0.000263768,0.00007093598,0.000030355526,0.00019128552,0.00046440706,0.0005159332],"category_scores_gemma":[0.00010657462,0.00037296847,0.00029831598,0.00030499758,0.00010085943,0.0000839218,0.00018674716,0.0004783685,0.00004322216],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018865753,0.00055043463,0.018578298,0.0006974629,0.001086402,0.000044488388,0.000014312753,0.00008782114,0.9766999,0.0011154832,0.0009183632,0.000018402772],"study_design_scores_gemma":[0.0012772641,0.00006026229,0.84171265,0.0005994982,0.00052410446,3.733294e-9,0.0000028710156,0.0007667415,0.15208486,0.00002464919,0.0025969618,0.0003501039],"about_ca_topic_score_codex":0.00006681219,"about_ca_topic_score_gemma":7.0730124e-7,"teacher_disagreement_score":0.824615,"about_ca_system_score_codex":0.00015101946,"about_ca_system_score_gemma":0.00096406497,"threshold_uncertainty_score":0.9998722},"labels":[],"label_agreement":null},{"id":"W4414380358","doi":"10.1016/j.bbamcr.2025.120061","title":"Corrigendum to “Inhibition of autophagy sensitises cells to hydrogen peroxide-induced apoptosis: Protective effect of mild thermotolerance acquired at 40 °C” [Biochim. Biophys. Acta Mol. Cell Res. (2016) volume 1863(12) 3050-3064 / PMID: 27666506]","year":2025,"lang":"en","type":"erratum","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Cell; Volume (thermodynamics); Autophagy; Hydrogen","score_opus":0.022137911922072696,"score_gpt":0.3062245325748891,"score_spread":0.28408662065281637,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414380358","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97267807,0.0014610924,0.00004827625,0.0011675315,0.002652513,0.011862093,0.0017026212,0.00023300946,0.008194778],"genre_scores_gemma":[0.94700253,0.0009311593,0.00025332434,0.00078821485,0.0007593358,0.0013534615,0.0014036681,0.00053246936,0.046975825],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.98572546,0.0027048101,0.0018979369,0.0033628517,0.003885091,0.0024238194],"domain_scores_gemma":[0.9913911,0.0003909395,0.0011253501,0.0040062037,0.0016695547,0.0014168087],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.0015841996,0.0020967487,0.003547718,0.002342896,0.00051017007,0.00014356468,0.0017090678,0.0019466187,0.00023745152],"category_scores_gemma":[0.00035709984,0.0019463403,0.0018955879,0.002951159,0.0007742857,0.00018632537,0.0016602677,0.0023732262,0.00032322528],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0076356158,0.0015537621,5.275627e-7,0.004155822,0.0009322403,0.0002345477,0.00076840335,0.000009347105,0.85623795,0.0000062927825,0.12807135,0.0003941647],"study_design_scores_gemma":[0.0035302213,0.006775343,0.00024683427,0.0039790715,0.0008368672,0.000007445476,0.000103619976,0.00017395469,0.97879386,0.000044647935,0.004097133,0.0014110111],"about_ca_topic_score_codex":0.000813791,"about_ca_topic_score_gemma":0.000012793196,"teacher_disagreement_score":0.12397421,"about_ca_system_score_codex":0.0010577965,"about_ca_system_score_gemma":0.0027187238,"threshold_uncertainty_score":0.99992836},"labels":[],"label_agreement":null},{"id":"W4414383439","doi":"10.1152/ajpcell.00471.2025","title":"Isolation of functional lysosomes from skeletal muscle","year":2025,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Skeletal muscle; Lysosome; Organelle; Mitochondrion; Autophagy; Function (biology); Myocyte; Enzyme","score_opus":0.006797273520678352,"score_gpt":0.25315844929860676,"score_spread":0.2463611757779284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414383439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99703604,0.0007992364,0.0006725887,0.0003899075,0.00047444296,0.000089974616,0.000016508997,0.000014716149,0.00050658995],"genre_scores_gemma":[0.9969871,0.0002051002,0.0008844502,0.0012555069,0.0004670788,0.0000038634057,0.00004859516,0.000014235744,0.0001340565],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9986592,0.00017648413,0.0005720659,0.00023340364,0.00014184188,0.00021701999],"domain_scores_gemma":[0.9983052,0.00029440006,0.0007519397,0.00028311598,0.00027249596,0.000092840404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009056666,0.00018129019,0.0008355322,0.00021915666,0.000050933642,0.0000022855131,0.00016416614,0.00008624447,0.00052782247],"category_scores_gemma":[0.000041346153,0.00014405882,0.00038161888,0.00031008862,0.00063301943,0.00008014782,0.00004462263,0.00029837908,0.000019444746],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011705979,0.0005059253,0.00051328796,0.00002815191,0.00044775498,0.0000034059485,0.000086650216,0.0002726891,0.99097514,0.00016942566,0.0014016621,0.004425306],"study_design_scores_gemma":[0.0028782303,0.0022201464,0.9008139,0.00007435095,0.00029807375,0.000008773821,0.00049913145,0.0002546517,0.08101091,0.010344922,0.0014539049,0.0001430185],"about_ca_topic_score_codex":0.00004970797,"about_ca_topic_score_gemma":6.3630847e-7,"teacher_disagreement_score":0.90996426,"about_ca_system_score_codex":0.00004154474,"about_ca_system_score_gemma":0.0002794193,"threshold_uncertainty_score":0.58745486},"labels":[],"label_agreement":null},{"id":"W4414800470","doi":"10.1016/j.biopha.2025.118620","title":"Autophagy inhibition enhances sensitivity of alpelisib in PI3K–mutated non-small cell lung cancer","year":2025,"lang":"en","type":"article","venue":"Biomedicine & Pharmacotherapy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"Ministry of Science and ICT, South Korea; National Research Foundation of Korea; Yuhan","keywords":"Autophagy; PI3K/AKT/mTOR pathway; Lung cancer; Apoptosis; Cancer; Cell growth; Cell; Cell culture","score_opus":0.00931478664570765,"score_gpt":0.3333545237424597,"score_spread":0.32403973709675205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414800470","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9813836,0.012050629,0.0016918506,0.00164702,0.0006375429,0.0010517356,0.000045962744,0.000099691155,0.0013919432],"genre_scores_gemma":[0.9873313,0.0060572997,0.00015404979,0.0047078785,0.00031813522,0.000102697435,0.00006674882,0.00003787174,0.0012240526],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980233,0.00014837843,0.0006510662,0.000447915,0.0003225899,0.00040680513],"domain_scores_gemma":[0.99901104,0.00013926918,0.00022145448,0.0002923398,0.00017388994,0.00016197983],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005366061,0.00032328596,0.0006987065,0.00068045163,0.000053002455,0.000008339063,0.00009198589,0.00014475075,0.0006990301],"category_scores_gemma":[0.000013864904,0.0002747631,0.00015559247,0.0012098493,0.00020181565,0.00009599944,0.000024121195,0.0002689317,0.0000074387362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011174746,0.000833389,0.011201898,0.0005849712,0.00023104748,0.00021478474,0.000736981,0.000018512606,0.9598956,0.000019444034,0.0037549285,0.021390973],"study_design_scores_gemma":[0.011731721,0.0002321376,0.04953795,0.0009771028,0.00021629363,0.0000073437723,0.000102202765,0.0048144916,0.9297795,0.000051914674,0.0023459306,0.00020340375],"about_ca_topic_score_codex":0.000841567,"about_ca_topic_score_gemma":0.000039944225,"teacher_disagreement_score":0.03833605,"about_ca_system_score_codex":0.00016871409,"about_ca_system_score_gemma":0.0004694404,"threshold_uncertainty_score":0.99997044},"labels":[],"label_agreement":null},{"id":"W4414877475","doi":"10.3389/fonc.2025.1675537","title":"Context-dependent rewiring of dual-function proteins in cancer: a sequential strategy to restore apoptosis","year":2025,"lang":"en","type":"review","venue":"Frontiers in Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McGill University","keywords":"Apoptosis; Programmed cell death; Crosstalk; Tumor microenvironment; Cancer cell; Cell; Cell fate determination; Cancer therapy","score_opus":0.05269228912948137,"score_gpt":0.3972286173589737,"score_spread":0.3445363282294923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414877475","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00086727855,0.9912798,0.0006371761,0.00010817447,0.0023770088,0.0033369083,0.000074315634,0.000030602303,0.0012887463],"genre_scores_gemma":[0.0016656667,0.9938516,0.00047716263,0.00022226268,0.00026401223,0.0017416978,0.00007841441,0.000041128198,0.00165805],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99744976,0.0003788881,0.0009781336,0.00056336424,0.00024295777,0.0003868983],"domain_scores_gemma":[0.9989486,0.00007737494,0.00033758208,0.0004342053,0.00007152852,0.00013076476],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000407296,0.00034819712,0.0027268538,0.0010447069,0.00002734151,0.000006324547,0.00018447332,0.00071296847,0.000112422764],"category_scores_gemma":[0.00011762369,0.00032109738,0.00035589805,0.00067893846,0.00008137165,0.000044960398,0.000085859996,0.000682339,0.000005734321],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006387176,0.00036491343,0.00033749724,0.009873363,0.0005548634,0.00014455948,0.00015523825,0.000026704205,0.00000927347,0.00012778664,0.0047955024,0.9829716],"study_design_scores_gemma":[0.0024954397,0.0018587661,0.0001545485,0.02252239,0.0013467483,0.000013950044,0.00029549788,0.000010601198,0.0000856827,0.00019513004,0.97071236,0.00030888614],"about_ca_topic_score_codex":0.00092750596,"about_ca_topic_score_gemma":0.00058199564,"teacher_disagreement_score":0.9826627,"about_ca_system_score_codex":0.0022290372,"about_ca_system_score_gemma":0.0033578614,"threshold_uncertainty_score":0.9999241},"labels":[],"label_agreement":null},{"id":"W4414877860","doi":"10.1002/ana.78013","title":"Mutations in the Key Autophagy Tethering Factor <scp>EPG5</scp> Link Neurodevelopmental and Neurodegenerative Disorders Including Early‐Onset Parkinsonism","year":2025,"lang":"en","type":"article","venue":"Annals of Neurology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; Children's Hospital of Eastern Ontario; University of British Columbia; University Health Network","funders":"Medizinische Fakultät, Universität zu Köln; National Institute of Neurological Disorders and Stroke; H2020 Marie Skłodowska-Curie Actions; HORIZON EUROPE Framework Programme; National Human Genome Research Institute; Estonian Research Competency Council; European Commission; Universität zu Köln; ZonMw; Horizon 2020 Framework Programme; Deutsche Forschungsgemeinschaft; Action Medical Research","keywords":"Parkinsonism; Autophagy; Disease; Parkinson's disease; Key (lock); Neurodevelopmental disorder","score_opus":0.046356737227213674,"score_gpt":0.33354885054095346,"score_spread":0.2871921133137398,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414877860","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98794675,0.00069020415,0.000072998504,0.009891269,0.00016643998,0.00037285467,0.000022214632,0.000036522284,0.00080077705],"genre_scores_gemma":[0.9853571,0.00078639796,0.0000662569,0.013581768,0.000037354403,0.00004638789,0.000014105985,0.000018996881,0.00009164704],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99856114,0.00030111196,0.00033348135,0.00034539224,0.00014910672,0.00030975172],"domain_scores_gemma":[0.9988579,0.0006832961,0.00010164053,0.00023603979,0.00005743997,0.00006366474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017266089,0.00019003438,0.00030644343,0.00023944858,0.00014515921,0.000019228048,0.00016888492,0.00010900502,0.000009417613],"category_scores_gemma":[0.00032114764,0.00015382802,0.00007028813,0.00037652306,0.00021649158,0.00008487002,0.000092949,0.0003763015,0.0000034050092],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010190936,0.001963283,0.76642656,0.000390568,0.0009217989,0.0012163848,0.0596521,0.00091402465,0.05263899,0.005716033,0.002829274,0.10631188],"study_design_scores_gemma":[0.0008917017,0.00047618,0.98242646,0.00001952119,0.000026126818,0.000030338952,0.00013136327,0.00054058596,0.007376343,0.0021930041,0.0058352323,0.000053127464],"about_ca_topic_score_codex":0.000052590294,"about_ca_topic_score_gemma":0.00003198128,"teacher_disagreement_score":0.2159999,"about_ca_system_score_codex":0.0000041839644,"about_ca_system_score_gemma":0.000108634034,"threshold_uncertainty_score":0.62729245},"labels":[],"label_agreement":null},{"id":"W4414890524","doi":"10.1139/bcb-2025-0085","title":"TGFB1-mediated autophagy facilitates oxaliplatin resistance in stomach adenocarcinoma","year":2025,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Autophagy; Oxaliplatin; Gene knockdown; Apoptosis; Carcinogenesis; Oncogene; Transfection; Cell growth; Cell","score_opus":0.007050615328951253,"score_gpt":0.25500168864850037,"score_spread":0.2479510733195491,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414890524","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9518929,0.03145827,0.000009900609,0.0003534981,0.000059895072,0.00013829094,0.00004723398,0.000046954847,0.015993033],"genre_scores_gemma":[0.98969644,0.00039127842,0.00011234887,0.00053388544,0.000037086513,0.000026510805,0.00018217995,0.000006005188,0.009014285],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909085,0.000040200608,0.00023077472,0.00035609305,0.000043758944,0.00023835046],"domain_scores_gemma":[0.99949676,0.000114178976,0.000043237877,0.00023046292,0.000028881186,0.00008649617],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000099208206,0.00015332058,0.0002597024,0.00006134559,0.000045798843,0.0000058027836,0.00007964699,0.00025017845,0.00013561241],"category_scores_gemma":[0.000064268505,0.00013676494,0.0000477299,0.00017982369,0.0001798611,0.000014007755,0.000036994046,0.00016414889,0.000012600654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054360327,0.00017873364,0.05154605,0.0003917379,0.000049617127,0.00007173337,0.00013239495,2.3036232e-7,0.94480586,0.00040921834,0.00091683323,0.00095397665],"study_design_scores_gemma":[0.0026191713,0.000090483954,0.09482934,0.000090914975,0.00003698505,0.0000051363145,0.00018575601,0.000054231736,0.8890576,0.0013051257,0.011544743,0.00018051751],"about_ca_topic_score_codex":0.000017153747,"about_ca_topic_score_gemma":0.0000036178928,"teacher_disagreement_score":0.05574828,"about_ca_system_score_codex":0.00003586294,"about_ca_system_score_gemma":0.000121769284,"threshold_uncertainty_score":0.55771124},"labels":[],"label_agreement":null},{"id":"W4414935717","doi":"10.1080/27694127.2025.2562429","title":"Influence of skeletal muscle heterogeneity on autophagic signaling and response","year":2025,"lang":"en","type":"review","venue":"Autophagy Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Skeletal muscle; Autophagy; Proteostasis; Organelle; Myocyte; Glycolysis; Flux (metallurgy); Lysosome","score_opus":0.022592999101016652,"score_gpt":0.34751903003725115,"score_spread":0.3249260309362345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414935717","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3797653,0.6190024,0.0000023586401,0.000009215823,0.00013028478,0.00077833456,0.000022216498,0.00009344333,0.00019645719],"genre_scores_gemma":[0.097827055,0.900502,0.00008573827,0.00023851819,0.000093082854,0.00012451987,0.00006445169,0.00006921397,0.0009953715],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963528,0.0003509799,0.0014679339,0.0009319562,0.00050258194,0.00039376662],"domain_scores_gemma":[0.99666643,0.000643435,0.0010128391,0.001273553,0.00013942744,0.00026431435],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008641782,0.00063648255,0.0025297105,0.00048388282,0.00010288339,0.00002274186,0.0001512846,0.0005073024,0.00006723155],"category_scores_gemma":[0.0006419147,0.0005219598,0.0007785901,0.00047863676,0.00021036067,0.000080527905,0.00013225988,0.0005033312,0.000014447871],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003367911,0.0007086319,0.00011828618,0.04420715,0.0014265699,0.016940327,0.00012998618,0.000057982685,0.0007316283,0.00014026761,0.00013830206,0.9350641],"study_design_scores_gemma":[0.001343062,0.0014341963,0.017619194,0.073767625,0.0052647726,0.0044755954,0.000010885866,0.000013980555,0.0057878504,0.00041496853,0.8885858,0.0012820631],"about_ca_topic_score_codex":0.000015058632,"about_ca_topic_score_gemma":3.6958892e-7,"teacher_disagreement_score":0.93378204,"about_ca_system_score_codex":0.00013577486,"about_ca_system_score_gemma":0.0014534126,"threshold_uncertainty_score":0.9997232},"labels":[],"label_agreement":null},{"id":"W4415038501","doi":"10.1083/jcb.202411184","title":"PEX14 acts as a molecular link between optineurin and the autophagic machinery to induce pexophagy","year":2025,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Herculesstichting; University of Illinois at Urbana-Champaign; Monash University; Universiteit van Amsterdam; Vlaamse regering; Fonds Wetenschappelijk Onderzoek; Ministry of Higher Education, Egypt; China Scholarship Council; Francis Crick Institute; KU Leuven; Albert-Ludwigs-Universität Freiburg; University of Toronto; Vlaams Instituut voor Biotechnologie","keywords":"Optineurin; Autophagy; Peroxisome; Colocalization; Bafilomycin; ATG8; ATG16L1; Membrane protein","score_opus":0.008945945129639131,"score_gpt":0.29819653601139445,"score_spread":0.2892505908817553,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415038501","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97138673,0.007394835,0.00035884327,0.014263541,0.00018388967,0.00026377852,0.0000024918036,0.000012157294,0.0061337426],"genre_scores_gemma":[0.9909435,0.0007019922,0.00012957757,0.0068887114,0.00040065154,0.0000030656722,0.0000019396052,0.000011709068,0.00091883447],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987976,0.0003962177,0.0003716585,0.00011226918,0.000115478295,0.00020676435],"domain_scores_gemma":[0.99877995,0.00050319405,0.0001983838,0.00028248856,0.00010238345,0.00013358788],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008663443,0.00014845179,0.0004268323,0.00014058335,0.000087923865,0.000012137096,0.00030054525,0.00010909965,0.000057289893],"category_scores_gemma":[0.00018801092,0.00006975322,0.00012983946,0.00018995805,0.00020156674,0.000023855235,0.00010874797,0.00048534904,0.000017947888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0058815638,0.00014529252,0.0012035236,0.00009124087,0.0010340804,0.0003344513,0.0015272225,0.000068234396,0.9495437,0.006162252,0.000805609,0.033202793],"study_design_scores_gemma":[0.012202328,0.002206991,0.038371604,0.00017152292,0.0014369965,0.00055175635,0.00023270815,0.00009214253,0.89384514,0.021472957,0.029175868,0.00023996989],"about_ca_topic_score_codex":0.000018037064,"about_ca_topic_score_gemma":3.4936085e-7,"teacher_disagreement_score":0.05569858,"about_ca_system_score_codex":0.000022302658,"about_ca_system_score_gemma":0.0001893885,"threshold_uncertainty_score":0.28444538},"labels":[],"label_agreement":null},{"id":"W4415095722","doi":"10.1080/27694127.2025.2560903","title":"The space-time continuum in neurological disorders of the autophagosome-lysosome fusion machinery","year":2025,"lang":"en","type":"review","venue":"Autophagy Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Thomas Hospital","funders":"Horizon 2020 Framework Programme; Great Ormond Street Hospital Charity; Action Medical Research","keywords":"Autophagy; Phenotype; Disease; mitochondrial fusion; Pathogenesis; Amyotrophic lateral sclerosis; Mechanism (biology); Neurodegeneration","score_opus":0.00881651477295917,"score_gpt":0.2924258019451918,"score_spread":0.2836092871722326,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415095722","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005472838,0.98455536,0.0000019567153,0.00062997954,0.0018940564,0.0026767647,0.000020292917,0.00012829414,0.004620432],"genre_scores_gemma":[0.003132173,0.9785575,0.000016184664,0.0003463886,0.00020279404,0.00027119243,0.000067564186,0.00007577856,0.017330404],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9952137,0.0006209202,0.0019597437,0.00088914623,0.00068679167,0.0006297012],"domain_scores_gemma":[0.9952187,0.0009740268,0.0014199633,0.00215382,0.0000801909,0.00015331007],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008887602,0.0007312209,0.0026552596,0.00027733264,0.0002437584,0.000038864287,0.0005783337,0.0006545357,0.00023147001],"category_scores_gemma":[0.00085423863,0.0003622202,0.0016835314,0.0011134094,0.00044761397,0.00006198708,0.0004701973,0.0011756783,0.000027275031],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014789353,0.00087409694,0.0027711778,0.008862254,0.00070314493,0.003213345,0.000074914635,0.0000032809778,0.00003719584,0.0005589764,0.0055072694,0.97724646],"study_design_scores_gemma":[0.0006422512,0.00017232752,0.014098256,0.00730743,0.0012757044,0.0007792764,0.0000041981916,0.00004180613,0.00004630195,0.0019241989,0.97332126,0.00038699267],"about_ca_topic_score_codex":0.000043107128,"about_ca_topic_score_gemma":0.000023129092,"teacher_disagreement_score":0.97685945,"about_ca_system_score_codex":0.00007621331,"about_ca_system_score_gemma":0.0011903486,"threshold_uncertainty_score":0.999883},"labels":[],"label_agreement":null},{"id":"W4415247385","doi":"10.1016/j.biopha.2025.118651","title":"Erratum to “Autophagy inhibition enhances sensitivity of alpelisib in PI3K–mutated non-small cell lung cancer” [Biomed. Pharmacother. 192 (2025), 118620]","year":2025,"lang":"en","type":"erratum","venue":"Biomedicine & Pharmacotherapy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Sensitivity (control systems); Cell; Lung; Human lung","score_opus":0.01235940809543696,"score_gpt":0.33679115025107964,"score_spread":0.3244317421556427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415247385","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6853792,0.16936131,0.0027623074,0.011748357,0.076265514,0.01503951,0.0034280978,0.0010611999,0.03495449],"genre_scores_gemma":[0.40452483,0.15081969,0.00083419087,0.04054433,0.015602663,0.0020106777,0.004965368,0.000957957,0.3797403],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.992451,0.0005528336,0.0021909496,0.0018794922,0.0014056781,0.0015200132],"domain_scores_gemma":[0.99592346,0.0002921994,0.0011179768,0.0010614146,0.0006725857,0.00093235524],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0013118881,0.001668828,0.0031277302,0.0031422228,0.00016260732,0.00004874708,0.0005400278,0.0010347394,0.0030234624],"category_scores_gemma":[0.00005111197,0.0015332059,0.0006988504,0.0038562042,0.00044736857,0.00020410161,0.00014802266,0.002018667,0.00005385785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019283142,0.0011947345,0.000259973,0.0025394934,0.0007494619,0.00063089415,0.0009080579,0.000014039627,0.49113232,0.000002353116,0.48979315,0.010847195],"study_design_scores_gemma":[0.017321408,0.00092646317,0.0023434232,0.0075448016,0.0013710298,0.000030653242,0.0001648345,0.002669641,0.7054596,0.00003460571,0.2608456,0.0012879344],"about_ca_topic_score_codex":0.0026610764,"about_ca_topic_score_gemma":0.0001755421,"teacher_disagreement_score":0.3447858,"about_ca_system_score_codex":0.0008842166,"about_ca_system_score_gemma":0.0031312613,"threshold_uncertainty_score":0.99960583},"labels":[],"label_agreement":null},{"id":"W4415722475","doi":"10.3389/fphys.2025.1664909","title":"Mitophagy as a therapeutic target for exercise-induced fatigue: modulation by natural compounds and mechanistic insights","year":2025,"lang":"en","type":"review","venue":"Frontiers in Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Department of Science and Technology of Jilin Province; Education Department of Jilin Province; People's Government of Jilin Province","keywords":"Mitophagy; Mitochondrion; Autophagy; Mechanism (biology); Oxidative phosphorylation; Intracellular","score_opus":0.023158435224762786,"score_gpt":0.32946837252231714,"score_spread":0.30630993729755435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415722475","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004408757,0.9932467,0.0018020623,0.000022547323,0.0019867856,0.00230544,0.00005393194,0.000051220602,0.00009044769],"genre_scores_gemma":[0.015721554,0.9795239,0.0011449354,0.00028156536,0.00017822381,0.0006869658,0.001691483,0.000057397374,0.0007139919],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998203,0.00016655998,0.0005083042,0.00065058266,0.00012488417,0.0003466645],"domain_scores_gemma":[0.99906147,0.00017630623,0.00023406083,0.00037574023,0.000059763024,0.00009263478],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000068872636,0.00048333823,0.0022772127,0.0003606702,0.000094663636,0.000013888166,0.00018440296,0.00053824444,0.000013810113],"category_scores_gemma":[0.0000419734,0.0003874961,0.0003266953,0.00027674576,0.000089265,0.000053423617,0.000045169254,0.00038484563,0.0000031933932],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00064261456,0.00030823308,0.0000047141175,0.02072251,0.0010359291,0.00001732363,0.00014621683,0.0000014615383,0.0014234638,0.0008658118,0.010513944,0.9643178],"study_design_scores_gemma":[0.006856603,0.0014317691,0.00019783304,0.019461814,0.0034296648,0.00003230316,0.00012336213,0.004857116,0.0005865088,0.16201459,0.7994811,0.0015273482],"about_ca_topic_score_codex":0.00000954937,"about_ca_topic_score_gemma":4.7354624e-7,"teacher_disagreement_score":0.9627904,"about_ca_system_score_codex":0.00015359282,"about_ca_system_score_gemma":0.00031217004,"threshold_uncertainty_score":0.9998577},"labels":[],"label_agreement":null},{"id":"W4415933175","doi":"10.1182/blood.2025030061","title":"PIKfyve inhibition in MM disrupts autophagy and lysosome function, increasing MHC expression and cholesterol metabolism","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto; Evonik (Canada); Systems, Applications & Products in Data Processing (Canada); Hospital for Sick Children; Princess Margaret Cancer Centre","funders":"National Cancer Institute; National Science Council; Regeneron Pharmaceuticals; Sanofi; Genentech; AstraZeneca; Amgen; Pfizer; Bristol-Myers Squibb; GlaxoSmithKline","keywords":"Autophagy; Downregulation and upregulation; Lysosome; Regulator; Cytotoxicity; Myeloid; Major histocompatibility complex; Cell culture","score_opus":0.0058201903199480735,"score_gpt":0.25002383291733354,"score_spread":0.24420364259738547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415933175","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99217856,0.006449435,0.000085704145,0.00024299625,0.000088796456,0.00027369446,0.000005188415,0.00005995224,0.00061567023],"genre_scores_gemma":[0.99827033,0.00035647556,0.00011292325,0.0009155795,0.000103933126,0.000033095555,0.00001953182,0.000012877656,0.00017523798],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99917257,0.00007360756,0.00020695805,0.00027010762,0.00011751389,0.00015926968],"domain_scores_gemma":[0.9996093,0.000046679852,0.00004635867,0.00017086642,0.000029701276,0.00009710568],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015361632,0.00013584213,0.00024280882,0.00019354768,0.00007913045,0.000030655854,0.000018995217,0.00010182477,0.00002561885],"category_scores_gemma":[0.000049970517,0.00011726029,0.0000317056,0.00017527484,0.000056936307,0.00016158479,0.000047361744,0.0001348342,0.000002998784],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012835608,0.0018059134,0.12001064,0.00047658305,0.00026088,0.00023957105,0.0012556938,0.000002056957,0.8510318,0.0016950662,0.00018785273,0.02175041],"study_design_scores_gemma":[0.008112361,0.00006366758,0.87313485,0.00045358363,0.00025941525,0.00006558544,0.00009550929,0.000030841875,0.115178734,0.0019958834,0.00050539675,0.0001041761],"about_ca_topic_score_codex":0.000042601303,"about_ca_topic_score_gemma":0.0000052304276,"teacher_disagreement_score":0.7531242,"about_ca_system_score_codex":0.000011876321,"about_ca_system_score_gemma":0.000039347535,"threshold_uncertainty_score":0.4781736},"labels":[],"label_agreement":null},{"id":"W4415971716","doi":"10.1101/2025.11.04.25339335","title":"Elenagen, a p62/SQSTM1-encoding plasmid, improves overall survival in platinum-resistant ovarian cancer patients: a phase II trial","year":2025,"lang":"","type":"preprint","venue":"medRxiv","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Gemcitabine; Clinical endpoint; Ovarian cancer; Overall survival; Survival analysis; Phases of clinical research; Clinical trial; Chemotherapy","score_opus":0.025699261997120748,"score_gpt":0.3234022214232914,"score_spread":0.29770295942617064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415971716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9674341,0.00434502,0.00014128188,0.0007628115,0.0131664295,0.006923939,0.0018149557,0.00019755018,0.0052138744],"genre_scores_gemma":[0.98384774,0.004498386,0.00015155948,0.0010574388,0.0026666059,0.0018488689,0.00054279185,0.00017429814,0.0052123223],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9889349,0.0009595667,0.0034932562,0.002820918,0.0018144952,0.0019768928],"domain_scores_gemma":[0.99431425,0.000745275,0.0015657512,0.0020116714,0.000488554,0.00087446824],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.0018173045,0.0018859003,0.0032371269,0.0011621035,0.00063863234,0.00019313014,0.0013318338,0.0013904468,0.003078776],"category_scores_gemma":[0.0012075992,0.0017895593,0.0010284557,0.0010168504,0.00034017253,0.00033975334,0.0013757286,0.002889858,0.00004886968],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.77274007,0.048154555,0.039879356,0.006698464,0.008996474,0.0020458095,0.016971467,0.0004905849,0.04813923,0.00422335,0.0021251272,0.0495355],"study_design_scores_gemma":[0.8494968,0.015963621,0.05724252,0.014843604,0.0037524698,0.000003572945,0.0007253938,0.009105283,0.013266313,0.0037569911,0.027156757,0.0046867165],"about_ca_topic_score_codex":0.0026267252,"about_ca_topic_score_gemma":0.0006497586,"teacher_disagreement_score":0.07675668,"about_ca_system_score_codex":0.0013911093,"about_ca_system_score_gemma":0.003703666,"threshold_uncertainty_score":0.99990594},"labels":[],"label_agreement":null},{"id":"W4416231371","doi":"10.3390/ijms262210994","title":"Repurposing Antimalarials for Oral Cancer: Selective Efficacy of Hydroxychloroquine on Gingival Squamous Cell Carcinoma","year":2025,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"King Saud University","keywords":"Hydroxychloroquine; Autophagy; Chloroquine; Apoptosis; Tongue; Viability assay; Drug repositioning; Transcriptome; Flow cytometry; Annexin","score_opus":0.016760032173722118,"score_gpt":0.35029836494674654,"score_spread":0.3335383327730244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416231371","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913644,0.0023358746,0.0027187185,0.00116515,0.00080912083,0.00018352333,0.000009821897,0.000005212283,0.0014081479],"genre_scores_gemma":[0.9975275,0.00004648406,0.0015371825,0.00065225665,0.00014206584,0.0000036434876,0.0000015395561,0.0000058383803,0.00008350503],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987441,0.0000390414,0.0003795731,0.00015258601,0.00055751787,0.00012718649],"domain_scores_gemma":[0.99877363,0.00017152658,0.00034698512,0.00007595765,0.00057899737,0.000052893007],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044837937,0.00009197694,0.0002454159,0.00034928773,0.00005566558,0.000028445893,0.0003198016,0.000036858626,0.000021327041],"category_scores_gemma":[0.00022376272,0.00007193155,0.00021522451,0.00022065,0.0001356701,0.00008602306,0.00002442839,0.00009469684,3.499323e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0052303,0.0014565794,0.018724347,0.000079535086,0.00061090046,0.0004330235,0.0005578503,0.0068717883,0.9303642,0.005401344,0.0009596982,0.029310456],"study_design_scores_gemma":[0.004051163,0.0014218639,0.014900171,0.00022662766,0.00015031743,0.000045901892,0.00006139553,0.0012379149,0.9758871,0.0013983671,0.00054248766,0.00007667498],"about_ca_topic_score_codex":0.000031042335,"about_ca_topic_score_gemma":7.3674425e-7,"teacher_disagreement_score":0.045522936,"about_ca_system_score_codex":0.0000849411,"about_ca_system_score_gemma":0.0005797631,"threshold_uncertainty_score":0.29332834},"labels":[],"label_agreement":null},{"id":"W4416331941","doi":"10.1152/ajpregu.00223.2025","title":"The effect of increasing levels of hyperthermia on autophagy and cellular stress in peripheral blood mononuclear cells from young adults","year":2025,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Hyperthermia; Peripheral blood mononuclear cell; Homeostasis; Heat shock; Heat shock protein; In vivo; Hsp70; Core temperature; Young adult","score_opus":0.0076634376193182255,"score_gpt":0.26480315233709856,"score_spread":0.25713971471778035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416331941","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99695826,0.0024368502,0.000015135596,0.000047443402,0.00011136711,0.0002682429,0.0000435318,0.0000054267066,0.000113744],"genre_scores_gemma":[0.99946034,0.00020440355,0.000112674985,0.00009890755,0.00007754228,0.000009327853,0.000005358786,0.000012066008,0.000019352263],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99750197,0.0011648814,0.0006389608,0.00031579522,0.00014318596,0.00023520997],"domain_scores_gemma":[0.9974605,0.0012123068,0.00076622155,0.0002678263,0.00020403705,0.00008913606],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023626348,0.00032775907,0.0015461467,0.00016477551,0.00009658473,0.0000065971653,0.00019644674,0.000087125336,0.000026426573],"category_scores_gemma":[0.000048943442,0.00018898869,0.00020282983,0.00022400924,0.0020027126,0.00006860459,0.00005645674,0.0004371464,5.5916956e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011820609,0.00026742465,0.0064373277,0.000045443925,0.0009884977,0.0000069017015,0.0022012347,0.00011022596,0.97360575,0.00048791032,0.00001897622,0.0040096994],"study_design_scores_gemma":[0.0023092688,0.005470746,0.46589294,0.0004325472,0.00013772643,0.0000051263887,0.0026678722,0.00032049677,0.5220702,0.0005941557,0.000007552513,0.00009134109],"about_ca_topic_score_codex":0.00032276844,"about_ca_topic_score_gemma":0.000024703011,"teacher_disagreement_score":0.4594556,"about_ca_system_score_codex":0.000037663147,"about_ca_system_score_gemma":0.00011234859,"threshold_uncertainty_score":0.7706735},"labels":[],"label_agreement":null},{"id":"W4416398157","doi":"10.1242/dmm.052214","title":"Autophagy inhibition in intestinal stem cells favors enteroendocrine cell differentiation through Stat92E activity","year":2025,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Université de Sherbrooke","keywords":"Autophagy; Enteroendocrine cell; Stem cell; Enterocyte; Cellular differentiation; Intestinal epithelium; Transcription factor; Homeostasis","score_opus":0.017574658836232465,"score_gpt":0.2667117898740015,"score_spread":0.24913713103776905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416398157","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7094283,0.00028981303,0.28839132,0.00027652804,0.0002544944,0.00069992425,0.00006935032,0.00015538317,0.00043487037],"genre_scores_gemma":[0.99669623,0.00014747269,0.0006334261,0.0010210774,0.00004466318,0.00018096602,0.00013711577,0.000041074047,0.0010980007],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99797,0.00013737175,0.00039563776,0.0006094335,0.0004243846,0.00046318886],"domain_scores_gemma":[0.9989769,0.000049231403,0.00013382509,0.00047751013,0.00009955008,0.00026298946],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000991125,0.00035182913,0.0004218651,0.00025757184,0.00010342829,0.00004462788,0.00010002517,0.00007639161,0.00014181284],"category_scores_gemma":[0.000007926135,0.00034081924,0.00021421858,0.0003427441,0.000041611194,0.00042519733,0.000098602315,0.00027528184,0.000029283166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008843363,0.011428663,0.0010255084,0.0024326483,0.00034968895,0.00268325,0.0017148667,0.0069547854,0.82967365,0.118037514,0.0008617263,0.015994355],"study_design_scores_gemma":[0.0046804775,0.00020818057,0.004186384,0.00049543014,0.00028440534,0.000004564306,0.00015986417,0.0961154,0.7670905,0.12642837,0.000036926496,0.00030948376],"about_ca_topic_score_codex":0.000070825525,"about_ca_topic_score_gemma":0.0000095795585,"teacher_disagreement_score":0.2877579,"about_ca_system_score_codex":0.0002680175,"about_ca_system_score_gemma":0.00024929346,"threshold_uncertainty_score":0.9999044},"labels":[],"label_agreement":null},{"id":"W4416439290","doi":"10.1113/ep093041","title":"Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse","year":2025,"lang":"en","type":"article","venue":"Experimental Physiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research","keywords":"Mitophagy; Skeletal muscle; Mitochondrion; Organelle; Lysosome","score_opus":0.007599228151154976,"score_gpt":0.3344997612378774,"score_spread":0.3269005330867224,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416439290","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9897401,0.009207009,0.0000011647968,0.000020361307,0.000086746215,0.00021518904,0.0000049590667,0.000017097384,0.00070739083],"genre_scores_gemma":[0.999392,0.00020730216,0.000033068838,0.000117351265,0.000033150827,0.000028970835,0.000017914082,0.000008993868,0.00016130056],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99939436,0.000028082255,0.0001706489,0.00019639765,0.000048713617,0.0001618194],"domain_scores_gemma":[0.99968827,0.000023613002,0.000037767513,0.00018317846,0.000010633915,0.000056549554],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000023822102,0.00011943319,0.00031950642,0.00010394536,0.000020675523,0.000002321759,0.00005240768,0.00006653408,0.00024800078],"category_scores_gemma":[0.0000072143207,0.00009660697,0.00011022542,0.00011753931,0.0001719106,0.00004263751,0.00005592872,0.000080167054,0.000005259089],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027375235,0.000768998,0.0013947205,0.000036268666,0.00006738506,0.000037398782,0.0003942749,0.0000027697056,0.99311817,0.00021339332,0.0002772829,0.0034156013],"study_design_scores_gemma":[0.0021093225,0.00037329854,0.8021029,0.00009821379,0.000013577961,0.000002421058,0.00021246733,0.000047582005,0.19450247,0.0003996978,0.000068346104,0.000069664966],"about_ca_topic_score_codex":0.00018229935,"about_ca_topic_score_gemma":0.0000011486076,"teacher_disagreement_score":0.80070823,"about_ca_system_score_codex":0.00004739677,"about_ca_system_score_gemma":0.00004960721,"threshold_uncertainty_score":0.39395177},"labels":[],"label_agreement":null},{"id":"W4416451661","doi":"10.1080/15548627.2025.2593585","title":"Regulation of pexophagy by a novel TBK1-MARCHF7-PXMP4-NBR1 axis in PEX1-depleted HeLa cells","year":2025,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Korea Institute for Advancement of Technology; National Research Foundation of Korea; Ministry of Science and ICT, South Korea; Ministry of Food and Drug Safety; Ministry of Trade, Industry and Energy; National Research Foundation","keywords":"Ubiquitin; Ubiquitin ligase; Phosphorylation; Peroxisome; Ubiquitin-Protein Ligases; Downregulation and upregulation; Gene knockdown; Serine; SUMO protein","score_opus":0.007249300076798487,"score_gpt":0.27083500498715796,"score_spread":0.2635857049103595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416451661","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9845211,0.0035293358,0.0019492144,0.0006826516,0.00038021023,0.00080945063,0.00008691934,0.00014892213,0.007892207],"genre_scores_gemma":[0.9900039,0.00013491476,0.00060702796,0.0011238969,0.00007474668,0.00005824747,0.00011780622,0.0000399505,0.0078395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979667,0.0000777029,0.00067251467,0.00048137244,0.00038269014,0.00041903465],"domain_scores_gemma":[0.9987236,0.00017432583,0.00017686636,0.00065268774,0.0001341422,0.00013833454],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027125247,0.0002791378,0.0006074164,0.00041342946,0.000060097813,0.000015048459,0.00021495405,0.00023626808,0.0006054714],"category_scores_gemma":[0.00009804987,0.00027231724,0.00020118312,0.0008492623,0.00015051842,0.00012413033,0.000072623465,0.00026396484,0.000050499188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006148134,0.0011239679,0.0013173278,0.0002783333,0.00020145881,0.00004577783,0.00041529958,0.000037511323,0.97583,0.0037003374,0.0075497064,0.008885421],"study_design_scores_gemma":[0.006477916,0.00030074955,0.1633137,0.0003351486,0.00013335753,0.000011306836,0.000098322664,0.0028842436,0.8128198,0.0022909697,0.01107206,0.00026243803],"about_ca_topic_score_codex":0.00023295176,"about_ca_topic_score_gemma":0.000015638403,"teacher_disagreement_score":0.16301025,"about_ca_system_score_codex":0.00014498312,"about_ca_system_score_gemma":0.00029722133,"threshold_uncertainty_score":0.9999729},"labels":[],"label_agreement":null},{"id":"W4416705497","doi":"10.1001/jamapsychiatry.2025.3580","title":"Autophagy in Stress-Induced Neuropsychiatric Disorders and Depression","year":2025,"lang":"en","type":"article","venue":"JAMA Psychiatry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Autophagy; Depression (economics); MEDLINE; Bipolar disorder; Mood disorders","score_opus":0.004406810452393353,"score_gpt":0.27303163216037435,"score_spread":0.268624821707981,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416705497","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9742472,0.0075734714,0.00004739084,0.005413077,0.0015528204,0.00036477743,0.000006052612,0.000097402946,0.010697782],"genre_scores_gemma":[0.9944471,0.00066036195,0.00040847392,0.0037662387,0.00023982493,0.000028912838,0.000011370099,0.000021951453,0.00041575741],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9988863,0.000055487068,0.00027101245,0.00038382702,0.0001513553,0.00025202017],"domain_scores_gemma":[0.999395,0.000038010538,0.00005811639,0.00037175583,0.000021507327,0.00011557257],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000081718565,0.0001799217,0.00024476278,0.0003432467,0.00007705528,0.000029220757,0.00010388116,0.00016228357,0.00007008621],"category_scores_gemma":[0.000041537704,0.00015760383,0.00008294044,0.00054906314,0.000033817538,0.000100312835,0.00004702574,0.00033328056,0.000012462536],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005151186,0.00065883173,0.9140655,0.00020289615,0.00005902913,0.00001722803,0.000111179615,0.0000045557344,0.0005458635,0.0023872806,0.0033287902,0.07810377],"study_design_scores_gemma":[0.0052233776,0.00010190735,0.98555803,0.0002535362,0.00006471813,0.0000064011165,0.00016781397,0.0002896622,0.00035790136,0.0063375128,0.0015033351,0.00013581984],"about_ca_topic_score_codex":0.000062765685,"about_ca_topic_score_gemma":0.00008193044,"teacher_disagreement_score":0.07796795,"about_ca_system_score_codex":0.000021521137,"about_ca_system_score_gemma":0.00019070259,"threshold_uncertainty_score":0.6426898},"labels":[],"label_agreement":null},{"id":"W4416758536","doi":"10.1038/s41467-025-65308-8","title":"Deleterious variants in the autophagy-related gene RB1CC1/FIP200 impair immunity to SARS-CoV-2","year":2025,"lang":"en","type":"article","venue":"Nature Communications","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Genome Canada; University of British Columbia; BC Children's Hospital; St. Paul's Hospital","funders":"H. Lundbeck A/S; Stavros Niarchos Foundation; Novo Nordisk; Fondation pour la Recherche Médicale; National Institutes of Health; Fisher Center for Alzheimer's Research Foundation; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Lundbeckfonden; Fondation du Souffle; Institut National de la Santé et de la Recherche Médicale; Novo Nordisk Fonden; Institut des maladies génétiques Imagine; National Research Foundation; Ministère de l'Enseignement supérieur, de la Recherche et de l'Innovation; National Institute of Allergy and Infectious Diseases; Danmarks Grundforskningsfond; CHIST-ERA; National Center for Advancing Translational Sciences; HORIZON EUROPE Framework Programme; Agence Nationale de la Recherche; Georgia Clinical and Translational Science Alliance; St. Giles Foundation","keywords":"Autophagy; Gene; Immunity; Function (biology); Interferon; Viral replication; RNA; HEK 293 cells; Innate immune system","score_opus":0.021880288836587703,"score_gpt":0.3604412245411649,"score_spread":0.3385609357045772,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416758536","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9392306,0.016505796,0.00009912802,0.025043486,0.0002343523,0.0011127113,0.000037997226,0.00016673107,0.017569162],"genre_scores_gemma":[0.97405505,0.0006602666,0.0016737035,0.02300894,0.000022809028,0.00014345812,0.00014649639,0.000017840244,0.00027140544],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985894,0.00038935087,0.00036942176,0.00020298774,0.00018820105,0.00026067125],"domain_scores_gemma":[0.9961398,0.00030479397,0.00006761077,0.0033050112,0.00013756959,0.000045193447],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004991006,0.00018051163,0.00027191683,0.00026590037,0.0003436832,0.000037454432,0.0014801053,0.000347179,0.000027101283],"category_scores_gemma":[0.00026370745,0.00013747609,0.00012985013,0.0013314969,0.000117266296,0.000070197755,0.00029597906,0.0015472469,0.00007264114],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012799741,0.010009668,0.020889547,0.00018145694,0.002336646,0.00037445218,0.017960984,0.000056365465,0.60501343,0.15200743,0.13672216,0.05316787],"study_design_scores_gemma":[0.0041103335,0.00025710848,0.8168163,0.00035997093,0.0003412634,0.00012745088,0.0005042484,0.0014612016,0.02743073,0.006531272,0.141613,0.00044714604],"about_ca_topic_score_codex":0.00016985784,"about_ca_topic_score_gemma":0.00027577332,"teacher_disagreement_score":0.79592675,"about_ca_system_score_codex":0.00013026522,"about_ca_system_score_gemma":0.00025773843,"threshold_uncertainty_score":0.6722104},"labels":[],"label_agreement":null},{"id":"W4417016989","doi":"10.1182/blood-2025-3316","title":"Autophagy/lysosome disruption via pikfyve inhibition in multiple myeloma","year":2025,"lang":"en","type":"article","venue":"Blood","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Systems, Applications & Products in Data Processing (Canada); Hospital for Sick Children; Princess Margaret Cancer Centre","funders":"","keywords":"Autophagy; Downregulation and upregulation; Cell culture; Proteasome; Ex vivo; Multiple myeloma; Phenotype; Ubiquitin","score_opus":0.010004865590765384,"score_gpt":0.2660244296044689,"score_spread":0.2560195640137035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417016989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949285,0.0009006797,0.00054267625,0.00039617365,0.00013521862,0.00037628453,0.000007225951,0.000121817575,0.0025914633],"genre_scores_gemma":[0.99788445,0.000061317005,0.00018493552,0.00080663385,0.00011640664,0.00006359613,0.00007187741,0.000013926108,0.00079684815],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99914783,0.00003491081,0.0002373425,0.00023549417,0.00014351726,0.0002008749],"domain_scores_gemma":[0.99956584,0.000040557898,0.000041976895,0.0002460521,0.000035546327,0.00007000925],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000921844,0.00012530935,0.00020631669,0.0002055728,0.000051964485,0.00001176505,0.000034936555,0.00010950511,0.00012504088],"category_scores_gemma":[0.00004850533,0.00011764039,0.00008759127,0.00033788817,0.000040153158,0.00009102143,0.00002542206,0.00014377903,0.00008885854],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010575943,0.00860601,0.23412336,0.0005413651,0.00048702426,0.0017541572,0.0010482724,0.000026775067,0.70202327,0.004361292,0.0006637871,0.045307122],"study_design_scores_gemma":[0.009925933,0.00015023214,0.6948363,0.00026788673,0.00015821791,0.000036894573,0.000056135155,0.0006505156,0.29009452,0.0030617844,0.0006170022,0.00014456676],"about_ca_topic_score_codex":0.000036224148,"about_ca_topic_score_gemma":0.000021364185,"teacher_disagreement_score":0.46071294,"about_ca_system_score_codex":0.00004829767,"about_ca_system_score_gemma":0.00006941104,"threshold_uncertainty_score":0.47972357},"labels":[],"label_agreement":null},{"id":"W4417483313","doi":"10.1016/j.cej.2025.171980","title":"TFEB-driven autophagy enhancement via a ROS-triggered NIR-II nanoplatform for targeted non-alcoholic fatty liver disease therapy","year":2025,"lang":"en","type":"article","venue":"Chemical Engineering Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of South China; National Natural Science Foundation of China; Natural Science Foundation of Hunan Province; Outstanding Youth Foundation of Jiangsu Province of China; Education Department of Hunan Province; Government of Xinjiang Uygur Autonomous Region of China; Outstanding Youth Scientist Foundation of Hunan Province; Spinal Cord Injury Canada","keywords":"Autophagy; Fatty liver; Therapeutic approach; Activator (genetics); TFEB; Signal transduction; Nanocarriers; Disease; Subcellular localization","score_opus":0.009646555328894808,"score_gpt":0.2551171731954758,"score_spread":0.24547061786658098,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417483313","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85762393,0.006242584,0.13415776,0.00036498805,0.00061877933,0.0007495439,0.000020533798,0.00014506734,0.0000767874],"genre_scores_gemma":[0.990867,0.00073993776,0.006036342,0.0008312595,0.0006282745,0.00015312855,0.00006751454,0.000057667257,0.0006188848],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983297,0.000006964706,0.00047607382,0.00031644458,0.00031573162,0.00055509864],"domain_scores_gemma":[0.9987785,0.00007421166,0.00010638587,0.00031365608,0.00015735591,0.0005698695],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013870288,0.0003394804,0.00047515778,0.00019113297,0.00017844437,0.000045342244,0.00023223307,0.00015986268,0.00027830046],"category_scores_gemma":[0.00010058289,0.0002864768,0.00042908243,0.00025979112,0.000046414134,0.00012912703,0.000056349934,0.00043971246,0.000012132316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012893655,0.0005868439,0.000113162176,0.0002253791,0.0006632218,0.00013024975,0.00017627045,0.00054373225,0.98187464,0.000110016175,0.0019214193,0.012365672],"study_design_scores_gemma":[0.007158658,0.00025502927,0.00398026,0.00043785543,0.00020490821,0.000060260725,0.000005440791,0.08991595,0.8878781,0.00029441484,0.009446399,0.00036272313],"about_ca_topic_score_codex":0.0000020271389,"about_ca_topic_score_gemma":3.275595e-8,"teacher_disagreement_score":0.13324304,"about_ca_system_score_codex":0.00026630965,"about_ca_system_score_gemma":0.00026423763,"threshold_uncertainty_score":0.99995875},"labels":[],"label_agreement":null},{"id":"W47168186","doi":"10.1016/s0076-6879(08)03235-7","title":"Chapter Thirty‐Five Quantitative Analysis of Autophagic Activity in Drosophila Neural Tissues by Measuring the Turnover Rates of Pathway Substrates","year":2008,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Autophagy; Cell biology; Biology; Lysosome; Western blot; Cytoplasm; Autophagy-related protein 13; Flux (metallurgy); Protein turnover; Biochemistry; Chemistry; Signal transduction; Enzyme; Protein biosynthesis; Gene; Apoptosis","score_opus":0.09355337638479501,"score_gpt":0.42899875876921045,"score_spread":0.33544538238441546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W47168186","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98774433,0.0060485746,0.0037103533,0.00045254742,0.00043303063,0.0007378099,0.00005337277,0.000044903572,0.0007750606],"genre_scores_gemma":[0.8579738,0.0004390914,0.14068268,0.00053603144,0.00003944704,0.00011543058,0.00002052982,0.000056385386,0.0001366146],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9862772,0.00979079,0.0016054433,0.0010813851,0.00038951612,0.00085565477],"domain_scores_gemma":[0.98834884,0.009417583,0.00085391174,0.0010328148,0.00020764263,0.00013923229],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0067561916,0.00065581803,0.002891761,0.0019587926,0.00010602904,0.000007057879,0.0006148117,0.0007805315,0.0003074422],"category_scores_gemma":[0.002392396,0.00051256217,0.0005096298,0.002436108,0.0020357259,0.00016189442,0.00016929906,0.0015026778,0.000004183434],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0050558625,0.0026260966,0.15919422,0.00014392183,0.002095731,0.0012274513,0.010868085,0.0026913015,0.7826582,0.013445262,0.000031359268,0.01996249],"study_design_scores_gemma":[0.0022741873,0.0011544083,0.7004152,0.00007323455,0.00030523105,0.00011469346,0.00040043567,0.0023763676,0.2853083,0.0071735107,0.000061204526,0.0003432175],"about_ca_topic_score_codex":0.001173165,"about_ca_topic_score_gemma":0.0006872494,"teacher_disagreement_score":0.541221,"about_ca_system_score_codex":0.00017585824,"about_ca_system_score_gemma":0.0001683593,"threshold_uncertainty_score":0.9997326},"labels":[],"label_agreement":null},{"id":"W568396243","doi":"10.6000/1929-2279.2015.04.02.8","title":"Metabolic Imbalance Associated Mitophagy in Tumor Cells: Genesis and Implications","year":2015,"lang":"en","type":"article","venue":"Journal of cancer research updates","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Mitophagy; Reprogramming; Mitochondrion; Carcinogenesis; Biology; Cancer research; Function (biology); Cell biology; Cancer; Bioinformatics; Genetics; Gene; Autophagy; Apoptosis","score_opus":0.07358224170101194,"score_gpt":0.42900684183951754,"score_spread":0.35542460013850563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W568396243","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9301163,0.06622925,0.0000042200927,0.0031977056,0.000083719584,0.00015179873,0.000022856675,0.000006725836,0.00018743462],"genre_scores_gemma":[0.9881104,0.010894275,0.00015581737,0.0003428795,0.0002686265,0.000025752815,0.0000031825125,0.000016191127,0.00018282724],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99855083,0.00016904218,0.0003295435,0.00012489302,0.0005292441,0.00029647117],"domain_scores_gemma":[0.99845034,0.00011485087,0.0001503488,0.0001555544,0.0007657863,0.0003631255],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011993713,0.00008483574,0.00032622975,0.0003234028,0.000048775513,0.000033643915,0.00015214489,0.000044693395,0.000083295265],"category_scores_gemma":[0.00028717032,0.00006472645,0.000060132927,0.0005063456,0.00011101687,0.00015335334,0.00003873558,0.00035716232,0.000007913488],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015765687,0.00096920313,0.7556826,0.00007947907,0.0007101616,0.0005030854,0.0011042788,0.000059726503,0.18193954,0.00047079026,0.041915767,0.0149888005],"study_design_scores_gemma":[0.0037491722,0.00033421093,0.8641132,0.00016906767,0.00006810174,0.00006459336,0.00038721456,0.00008464991,0.10445235,0.0028485581,0.02362336,0.00010551547],"about_ca_topic_score_codex":0.00027871932,"about_ca_topic_score_gemma":0.00006504827,"teacher_disagreement_score":0.10843061,"about_ca_system_score_codex":0.00016600861,"about_ca_system_score_gemma":0.00078610936,"threshold_uncertainty_score":0.2639468},"labels":[],"label_agreement":null},{"id":"W59711999","doi":"10.1155/2011/581264","title":"Autophagy: A Primer for the Gastroenterologist/Hepatologist","year":2011,"lang":"en","type":"review","venue":"Canadian Journal of Gastroenterology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Foundation of Canada; Crohn's and Colitis Foundation","keywords":"Autophagy; Cell biology; ATG16L1; Biology; Intracellular; Disease; Cytosol; Medicine; Biochemistry; Apoptosis; Enzyme","score_opus":0.07220081696037549,"score_gpt":0.32922328804753587,"score_spread":0.25702247108716036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W59711999","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00032372048,0.9949938,0.0013263309,0.00045655837,0.0015106458,0.0010944896,0.00015808799,0.0000125272945,0.00012385071],"genre_scores_gemma":[0.0016980219,0.994382,0.00051487284,0.0020408465,0.0007977228,0.000109684435,0.00004618447,0.00009150507,0.0003191553],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99719393,0.00024514066,0.0011876759,0.00031063464,0.00012609137,0.0009365368],"domain_scores_gemma":[0.9967411,0.00018472674,0.0012118724,0.00059720036,0.0002918512,0.00097320473],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00055006414,0.00050451676,0.0024624306,0.0005520042,0.00017454737,0.000029716504,0.0008034461,0.00037531427,0.0004079891],"category_scores_gemma":[0.00019143763,0.00029969445,0.001755337,0.000113392816,0.0006806998,0.00005608631,0.000029674467,0.00089581753,0.000027429956],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0045900834,0.00043147162,0.013754603,0.008537693,0.01389516,0.005021086,0.00027715607,0.000002265139,9.857367e-7,0.0013304353,0.079467274,0.8726918],"study_design_scores_gemma":[0.001426598,0.003944911,0.00072685216,0.0016891386,0.0042293463,0.009331902,0.000014079854,0.0000030556696,7.6054647e-7,0.00007620968,0.97845286,0.00010429696],"about_ca_topic_score_codex":0.00040514904,"about_ca_topic_score_gemma":0.0020710018,"teacher_disagreement_score":0.89898556,"about_ca_system_score_codex":0.00026787168,"about_ca_system_score_gemma":0.0026029022,"threshold_uncertainty_score":0.9999455},"labels":[],"label_agreement":null},{"id":"W6894348044","doi":"10.5683/sp3/5q8sek","title":"Environics Focus Ontario 2002-1","year":2009,"lang":"en","type":"dataset","venue":"Borealis","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Innovative Research Group (Canada)","funders":"","keywords":"Focus (optics); Public opinion; Field (mathematics); Focus group; Government (linguistics)","score_opus":0.013584933001037318,"score_gpt":0.26354905932127864,"score_spread":0.24996412632024131,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6894348044","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000031518197,0.0033000403,0.0000028041998,0.0002764974,0.000058659065,0.00032863204,0.9896596,0.000050684688,0.0062915822],"genre_scores_gemma":[0.000007854854,0.0022831073,0.00005212818,0.0023316762,0.0005411297,0.000021656193,0.9928002,0.00002604559,0.0019362227],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99861574,0.00002622194,0.00028013016,0.00036222232,0.0003807701,0.00033490674],"domain_scores_gemma":[0.9983928,0.000021413816,0.00013030207,0.0011550215,0.00003748636,0.0002629379],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000079742385,0.00033013528,0.0005152838,0.00010956398,0.000059745515,0.000021824973,0.00022573481,0.0004442882,0.005784735],"category_scores_gemma":[0.000025213261,0.0002841857,0.00024398242,0.00005956824,0.000058581616,0.000034978977,0.00003399181,0.00054832106,0.0002883077],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011450695,0.00026129198,0.0000051011834,0.000030444853,0.0001650297,0.00069412065,0.000025842795,3.0265275e-7,0.0000016603668,0.000015952979,0.9921417,0.0065440037],"study_design_scores_gemma":[0.0009127917,0.00033267523,0.0037377062,0.00009730831,0.0005353763,0.00006210047,0.0000029180828,6.5770877e-7,0.00006134365,0.00026354092,0.993731,0.00026255928],"about_ca_topic_score_codex":0.5279483,"about_ca_topic_score_gemma":0.5157898,"teacher_disagreement_score":0.012158523,"about_ca_system_score_codex":0.00036845496,"about_ca_system_score_gemma":0.00071513007,"threshold_uncertainty_score":0.999961},"labels":[],"label_agreement":null},{"id":"W6901710509","doi":"10.60692/8tkd0-ahb09","title":"Additional file 5 of QKI degradation in macrophage by RNF6 protects mice from MRSA infection via enhancing PI3K p110β dependent autophagy","year":2022,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Autophagy; Macrophage; PI3K/AKT/mTOR pathway; Degradation (telecommunications); Downregulation and upregulation; Proteolysis","score_opus":0.010318976327011795,"score_gpt":0.19722093834207088,"score_spread":0.1869019620150591,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6901710509","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.80904275,0.000021145026,0.004525908,0.000012727293,0.00021830318,0.0010637442,0.18405809,0.00016028227,0.0008970365],"genre_scores_gemma":[0.9526561,3.4676378e-7,0.00021796895,0.00016496197,0.00006313219,0.0014822279,0.04502428,0.000015359377,0.0003756018],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.9981976,0.00012926695,0.0007333985,0.00018214583,0.0005569869,0.00020059524],"domain_scores_gemma":[0.9989908,0.000055235516,0.0005159936,0.00023937866,0.000112558344,0.0000860614],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00017817158,0.00017564998,0.00028560104,0.00032056184,0.00015648734,0.000030026195,0.00008819789,0.000094072115,0.12721883],"category_scores_gemma":[0.00005049157,0.00017362756,0.00009333847,0.00032643863,0.000018714914,0.0004552384,0.000057864396,0.00021586979,0.00034577274],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005482236,0.00060798257,0.029696077,0.005394126,0.0015454931,0.00025310376,0.12710848,0.0023964862,0.012565771,0.00010363876,0.78710496,0.027741648],"study_design_scores_gemma":[0.020683778,0.0019297858,0.50654024,0.0036486727,0.00036276956,0.00049125555,0.022122806,0.04783474,0.3063137,0.00004428448,0.087976545,0.0020514212],"about_ca_topic_score_codex":0.00018393327,"about_ca_topic_score_gemma":0.0000029354924,"teacher_disagreement_score":0.6991284,"about_ca_system_score_codex":0.00044157216,"about_ca_system_score_gemma":0.00013106412,"threshold_uncertainty_score":0.873579},"labels":[],"label_agreement":null},{"id":"W6901711483","doi":"10.60692/2699d-6rb56","title":"The nucleoprotein of influenza A virus inhibits the innate immune response by inducing mitophagy","year":2023,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Mitophagy; Nucleoprotein; Autophagy; Innate immune system; Virus; Influenza A virus; Mitochondrion; Viral replication","score_opus":0.0268155151989056,"score_gpt":0.2507848005853284,"score_spread":0.22396928538642283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6901711483","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997969,0.000091541275,0.00008776362,0.00032247364,0.00019343977,0.00076763396,0.000079568665,0.00017899924,0.00030961656],"genre_scores_gemma":[0.9988292,0.0000022356191,0.0000068404315,0.00056953554,0.00004627291,0.00013194192,0.000014459075,0.000016372704,0.00038313412],"study_design_codex":"qualitative","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982714,0.00018816312,0.00076529116,0.000103116836,0.00041864355,0.00025335746],"domain_scores_gemma":[0.9987011,0.00005109476,0.0003954188,0.000608899,0.00017257605,0.00007093897],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001352222,0.00015693322,0.00023041929,0.00017227378,0.00031020952,0.00007983545,0.00020367528,0.000103270075,0.000012002952],"category_scores_gemma":[0.00012469366,0.000084955915,0.00011401668,0.0005900468,0.00008658731,0.00021204642,0.000080667145,0.00015493705,0.0005955919],"study_design_candidate":"qualitative","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.036554,0.00005738199,0.061112557,0.0028766594,0.002463361,0.00010625631,0.80135673,0.0004351285,0.06393947,0.0012905075,0.013642614,0.016165363],"study_design_scores_gemma":[0.0070868833,0.0004468156,0.43876082,0.00115832,0.000118154014,0.00010723415,0.047934897,0.0018627814,0.48504302,0.000012029917,0.017047402,0.0004216367],"about_ca_topic_score_codex":0.000023412003,"about_ca_topic_score_gemma":9.186624e-8,"teacher_disagreement_score":0.7534218,"about_ca_system_score_codex":0.000056981855,"about_ca_system_score_gemma":0.000086530206,"threshold_uncertainty_score":0.7655328},"labels":[],"label_agreement":null},{"id":"W6901720813","doi":"10.60692/9yy64-nx160","title":"Autophagy and its mediated mitochondrial quality control maintain pollen tube growth and male fertility in Arabidopsis","year":2022,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; University of Ottawa","funders":"","keywords":"Autophagy; Pollen tube; Arabidopsis; Pollen; Crosstalk; Organelle; Organelle biogenesis; Mitochondrion; Biogenesis","score_opus":0.02094413752922463,"score_gpt":0.23997476492795428,"score_spread":0.21903062739872964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6901720813","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99689895,0.00007000789,0.00028349494,0.00026092952,0.00022308766,0.00093195215,0.00042633567,0.00010415172,0.00080110045],"genre_scores_gemma":[0.99887633,9.0188576e-7,0.000024485826,0.0006884598,0.000048865764,0.00021151478,0.000056716937,0.0000096846725,0.000083044106],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998207,0.00029479963,0.00068434805,0.00019838507,0.00036858837,0.0002469124],"domain_scores_gemma":[0.9993095,0.000037049354,0.00019785724,0.00021365179,0.000069424896,0.00017254763],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053674256,0.0001724882,0.00041877342,0.0002438937,0.00016307629,0.00004470838,0.00007556127,0.000085858555,0.00019796201],"category_scores_gemma":[0.00008708729,0.00015339165,0.00006022571,0.00021113243,0.000034998513,0.00030354565,0.00006719708,0.00017675357,0.000033705233],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008456118,0.000057086218,0.91542935,0.0019922648,0.0003591101,0.00012459503,0.07057519,0.000035978042,0.00033379204,0.0020840256,0.000103268714,0.00044924504],"study_design_scores_gemma":[0.0130373845,0.00018274502,0.9703678,0.0000637451,0.000064802,0.0001379356,0.010387406,0.004769449,0.00068866793,0.000012982481,0.00006665484,0.00022043112],"about_ca_topic_score_codex":0.000047253834,"about_ca_topic_score_gemma":4.896095e-7,"teacher_disagreement_score":0.060187783,"about_ca_system_score_codex":0.00014631254,"about_ca_system_score_gemma":0.00007619258,"threshold_uncertainty_score":0.625513},"labels":[],"label_agreement":null},{"id":"W6901818285","doi":"10.60692/qdzrq-q0623","title":"Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase","year":2018,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Agriculture and Agri-Food Canada","funders":"","keywords":"Autophagy; Virus; RNA; Viral structural protein; Polymerase; Mutant; Intracellular; Viral protein","score_opus":0.030454127636750244,"score_gpt":0.2576262244630193,"score_spread":0.22717209682626907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6901818285","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973194,0.000013918151,0.0006983027,0.000030771054,0.00028826317,0.00035544205,0.000039269282,0.00003942035,0.0012152242],"genre_scores_gemma":[0.99962735,0.000004000954,0.000033516153,0.0001688979,0.000076161166,0.000014685838,0.000018547245,0.000005209664,0.0000516402],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9991426,0.000057812755,0.0004006767,0.00008147333,0.00020650834,0.00011096551],"domain_scores_gemma":[0.9994362,0.000006351167,0.00023621491,0.00021965036,0.00006310008,0.000038468082],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001227152,0.00009625733,0.00015374049,0.0001234025,0.00008363491,0.000020740694,0.00003970269,0.00009001763,0.000013509847],"category_scores_gemma":[0.000017993165,0.00006116723,0.000037329497,0.00015710921,0.00005148343,0.00047130277,0.000027948554,0.00007009256,0.00003255413],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009307232,0.00001735816,0.95553255,0.00039381464,0.00005099033,0.0000037282466,0.03948248,0.000010116357,0.00093806675,0.00016458554,0.00014846213,0.002327097],"study_design_scores_gemma":[0.0021358607,0.00012521152,0.84231615,0.00047056732,0.000029652352,0.0000331611,0.0008242293,0.0009915205,0.15290625,0.000007806319,0.00008209315,0.00007749567],"about_ca_topic_score_codex":0.00019293644,"about_ca_topic_score_gemma":0.000002462696,"teacher_disagreement_score":0.15196818,"about_ca_system_score_codex":0.000050555514,"about_ca_system_score_gemma":0.00003755016,"threshold_uncertainty_score":0.24943271},"labels":[],"label_agreement":null},{"id":"W6902024695","doi":"10.6084/m9.figshare.26602936.v1","title":"Additional file 1 of Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; McMaster University; University of Manitoba","funders":"","keywords":"Autophagy; Senescence; Glycolysis; Glioblastoma; Tumor cells; Metabolism","score_opus":0.01774706220372753,"score_gpt":0.2808810288174589,"score_spread":0.2631339666137314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6902024695","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3223106,0.00092448643,8.956949e-8,0.000009474747,0.000008659989,0.0001362335,0.6765244,0.00004471588,0.000041320363],"genre_scores_gemma":[0.6974036,0.000001765401,0.00003836805,0.00003541956,0.000070550304,0.00017827538,0.30206472,0.000016014834,0.00019128548],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.9991863,0.00002395955,0.00022809335,0.00025741608,0.00016272173,0.00014152404],"domain_scores_gemma":[0.99900264,0.0006236304,0.000057928373,0.00014568004,0.000062651605,0.000107480504],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000018080575,0.00012805751,0.00024337952,0.00013941101,0.000054458837,0.00003905569,0.00004943295,0.00006791429,0.82754964],"category_scores_gemma":[0.00021162165,0.000121977755,0.00006106294,0.00021653563,0.0000432112,0.000106983476,0.00004940383,0.000097085795,0.00009514547],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017877122,0.00014779226,0.004074762,0.0026826803,0.00028693362,0.0017245963,0.00029354682,0.000042343683,0.00061876635,0.000017289221,0.98320794,0.006724602],"study_design_scores_gemma":[0.0006126012,0.00018669665,0.92022324,0.008478655,0.000050327573,0.00031275142,0.000029469355,0.0032301664,0.0054216073,0.00013920612,0.06106908,0.000246193],"about_ca_topic_score_codex":0.000007316749,"about_ca_topic_score_gemma":0.00001385189,"teacher_disagreement_score":0.9221388,"about_ca_system_score_codex":0.000028067987,"about_ca_system_score_gemma":0.00009751657,"threshold_uncertainty_score":0.49741083},"labels":[],"label_agreement":null},{"id":"W6902089197","doi":"10.6084/m9.figshare.21971683","title":"PRKN/parkin-mediated mitophagy is induced by the probiotics <i>Saccharomyces boulardii</i> and <i>Lactococcus lactis</i>","year":2023,"lang":"en","type":"article","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Mitophagy; Mitochondrion; Neurodegeneration; Downregulation and upregulation; Probiotic; Parkinson's disease","score_opus":0.031813644986160336,"score_gpt":0.28325496281789236,"score_spread":0.251441317831732,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6902089197","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7423467,0.0079005305,4.379899e-7,0.008685831,0.000360902,0.004064576,0.23030533,0.0012860012,0.00504968],"genre_scores_gemma":[0.9498543,0.00012012833,0.0000069758826,0.0072571593,0.00029792383,0.00037842098,0.04050996,0.000068140005,0.0015069584],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99860734,0.00004970907,0.0002333724,0.00036699817,0.00033363962,0.0004089336],"domain_scores_gemma":[0.9988823,0.00023555815,0.00011439866,0.00044639458,0.00009516874,0.00022616012],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000070640504,0.0002526679,0.0002977009,0.0000701463,0.0001847985,0.000079409816,0.00019659052,0.00019700947,0.016098415],"category_scores_gemma":[0.00030737414,0.0001762379,0.0001128467,0.0004996028,0.000024504101,0.00011442874,0.00011426225,0.0003249572,0.0023583365],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008081577,0.00007111341,0.0002987556,0.00022053614,0.00017791874,0.000091925096,0.0003553859,2.125032e-7,0.01682294,0.0000024231254,0.979802,0.0020759848],"study_design_scores_gemma":[0.002537564,0.0003330039,0.020793023,0.000991072,0.00012505233,0.00005313882,0.00019428456,0.00019892237,0.14447561,0.00009760344,0.8297712,0.00042949826],"about_ca_topic_score_codex":0.000008053175,"about_ca_topic_score_gemma":0.0000018566077,"teacher_disagreement_score":0.20750761,"about_ca_system_score_codex":0.000028427507,"about_ca_system_score_gemma":0.00012999456,"threshold_uncertainty_score":0.99841845},"labels":[],"label_agreement":null},{"id":"W6902097377","doi":"10.6084/m9.figshare.12284756","title":"Additional file 1 of Activated CAMKKβ-AMPK signaling promotes autophagy in a spheroid model of ovarian tumour metastasis","year":2020,"lang":"en","type":"article","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"","keywords":"Autophagy; Transfection; Spheroid; Gene knockdown; Cell culture; Metastasis; Cell; Downregulation and upregulation","score_opus":0.055394941978363234,"score_gpt":0.26186066951841125,"score_spread":0.20646572754004802,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6902097377","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008134349,0.00007761562,0.0000030273877,0.000086347216,0.0000030071303,0.00028575124,0.9906485,0.0000432071,0.00071816385],"genre_scores_gemma":[0.4062954,4.6665843e-7,0.0016500317,0.0002521107,0.00005108943,0.00026932286,0.591378,0.000023085006,0.00008054503],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990258,0.000032989024,0.00030843582,0.00021350216,0.00025427336,0.00016498001],"domain_scores_gemma":[0.9990938,0.00030920884,0.00018775181,0.00013911861,0.00013556649,0.00013460686],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000017441818,0.00014079711,0.00036049358,0.000062859435,0.000020460746,0.0000047933017,0.000112806636,0.000078963654,0.9817411],"category_scores_gemma":[0.0014720968,0.00013191691,0.00013932199,0.00028293615,0.000011049831,0.000088934336,0.000041747964,0.0001558198,0.0001816481],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020964586,0.00022490484,0.0000016081682,0.00045574768,0.00013194693,0.000052886113,0.0003010364,0.0005141126,0.073193744,0.0000076113697,0.9242453,0.00066144735],"study_design_scores_gemma":[0.002500118,0.00045754825,0.0020125601,0.0071910145,0.000085775624,0.000012328731,0.0001721421,0.051454797,0.9150323,0.00031881485,0.020410305,0.0003522698],"about_ca_topic_score_codex":0.0000068398026,"about_ca_topic_score_gemma":0.0000011953382,"teacher_disagreement_score":0.98155946,"about_ca_system_score_codex":0.000024338631,"about_ca_system_score_gemma":0.00037665057,"threshold_uncertainty_score":0.5379415},"labels":[],"label_agreement":null},{"id":"W6902099812","doi":"10.6084/m9.figshare.21971683.v1","title":"PRKN/parkin-mediated mitophagy is induced by the probiotics <i>Saccharomyces boulardii</i> and <i>Lactococcus lactis</i>","year":2023,"lang":"en","type":"article","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Mitophagy; Mitochondrion; Neurodegeneration; Downregulation and upregulation; Probiotic; Parkinson's disease","score_opus":0.031813644986160336,"score_gpt":0.28325496281789236,"score_spread":0.251441317831732,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6902099812","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7423467,0.0079005305,4.379899e-7,0.008685831,0.000360902,0.004064576,0.23030533,0.0012860012,0.00504968],"genre_scores_gemma":[0.9498543,0.00012012833,0.0000069758826,0.0072571593,0.00029792383,0.00037842098,0.04050996,0.000068140005,0.0015069584],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99860734,0.00004970907,0.0002333724,0.00036699817,0.00033363962,0.0004089336],"domain_scores_gemma":[0.9988823,0.00023555815,0.00011439866,0.00044639458,0.00009516874,0.00022616012],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000070640504,0.0002526679,0.0002977009,0.0000701463,0.0001847985,0.000079409816,0.00019659052,0.00019700947,0.016098415],"category_scores_gemma":[0.00030737414,0.0001762379,0.0001128467,0.0004996028,0.000024504101,0.00011442874,0.00011426225,0.0003249572,0.0023583365],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008081577,0.00007111341,0.0002987556,0.00022053614,0.00017791874,0.000091925096,0.0003553859,2.125032e-7,0.01682294,0.0000024231254,0.979802,0.0020759848],"study_design_scores_gemma":[0.002537564,0.0003330039,0.020793023,0.000991072,0.00012505233,0.00005313882,0.00019428456,0.00019892237,0.14447561,0.00009760344,0.8297712,0.00042949826],"about_ca_topic_score_codex":0.000008053175,"about_ca_topic_score_gemma":0.0000018566077,"teacher_disagreement_score":0.20750761,"about_ca_system_score_codex":0.000028427507,"about_ca_system_score_gemma":0.00012999456,"threshold_uncertainty_score":0.99841845},"labels":[],"label_agreement":null},{"id":"W6902146978","doi":"10.6084/m9.figshare.12284756.v1","title":"Additional file 1 of Activated CAMKKβ-AMPK signaling promotes autophagy in a spheroid model of ovarian tumour metastasis","year":2020,"lang":"en","type":"article","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"","keywords":"Autophagy; Transfection; Spheroid; Gene knockdown; Cell culture; Metastasis; Cell; Downregulation and upregulation","score_opus":0.055394941978363234,"score_gpt":0.26186066951841125,"score_spread":0.20646572754004802,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6902146978","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008134349,0.00007761562,0.0000030273877,0.000086347216,0.0000030071303,0.00028575124,0.9906485,0.0000432071,0.00071816385],"genre_scores_gemma":[0.4062954,4.6665843e-7,0.0016500317,0.0002521107,0.00005108943,0.00026932286,0.591378,0.000023085006,0.00008054503],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990258,0.000032989024,0.00030843582,0.00021350216,0.00025427336,0.00016498001],"domain_scores_gemma":[0.9990938,0.00030920884,0.00018775181,0.00013911861,0.00013556649,0.00013460686],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000017441818,0.00014079711,0.00036049358,0.000062859435,0.000020460746,0.0000047933017,0.000112806636,0.000078963654,0.9817411],"category_scores_gemma":[0.0014720968,0.00013191691,0.00013932199,0.00028293615,0.000011049831,0.000088934336,0.000041747964,0.0001558198,0.0001816481],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020964586,0.00022490484,0.0000016081682,0.00045574768,0.00013194693,0.000052886113,0.0003010364,0.0005141126,0.073193744,0.0000076113697,0.9242453,0.00066144735],"study_design_scores_gemma":[0.002500118,0.00045754825,0.0020125601,0.0071910145,0.000085775624,0.000012328731,0.0001721421,0.051454797,0.9150323,0.00031881485,0.020410305,0.0003522698],"about_ca_topic_score_codex":0.0000068398026,"about_ca_topic_score_gemma":0.0000011953382,"teacher_disagreement_score":0.98155946,"about_ca_system_score_codex":0.000024338631,"about_ca_system_score_gemma":0.00037665057,"threshold_uncertainty_score":0.5379415},"labels":[],"label_agreement":null},{"id":"W6902524217","doi":"10.6084/m9.figshare.29604845.v1","title":"Additional file 1 of Targeting autophagy and plasminogen activator inhibitor-1 increases survival and remodels the tumor microenvironment in glioblastoma","year":2025,"lang":"en","type":"article","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Glioblastoma; Autophagy; Tumor microenvironment; Plasminogen activator; Activator (genetics); Tumor cells","score_opus":0.010030470148393733,"score_gpt":0.230094950429938,"score_spread":0.22006448028154427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6902524217","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.18916309,0.0005679293,6.2578295e-8,0.000051260486,0.000007796237,0.0002018153,0.80955124,0.000013488404,0.00044329782],"genre_scores_gemma":[0.6719957,0.000016200349,0.00014989015,0.0005768527,0.00013847319,0.0005907798,0.32592794,0.000022504344,0.0005816893],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993428,0.00004001977,0.0001708463,0.0001854721,0.00012908956,0.00013177229],"domain_scores_gemma":[0.9988347,0.00089074206,0.00007331112,0.000121476325,0.000021399903,0.00005834008],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00002670354,0.00011204721,0.00018112459,0.00006378867,0.0000594691,0.000010056636,0.000053869,0.000044828328,0.78157395],"category_scores_gemma":[0.000748564,0.00008580473,0.00003524818,0.00009657402,0.000032876782,0.000056818204,0.00009876015,0.000108487344,0.000032737156],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001596397,0.00009244258,0.00006299335,0.00014307679,0.00003895923,0.000035890134,0.00003824738,0.0000015806258,0.001253748,0.0000058206465,0.99713403,0.0010335945],"study_design_scores_gemma":[0.0029001366,0.00032502337,0.25454664,0.011044751,0.000057424415,0.000066058456,0.00058312604,0.001134725,0.09081736,0.00023869814,0.637942,0.0003440398],"about_ca_topic_score_codex":0.000007850685,"about_ca_topic_score_gemma":0.000003726002,"teacher_disagreement_score":0.7815412,"about_ca_system_score_codex":0.000032091324,"about_ca_system_score_gemma":0.00010467976,"threshold_uncertainty_score":0.34990153},"labels":[],"label_agreement":null},{"id":"W6917719367","doi":"10.57907/mirri/suzcaj","title":"MIRRI0051604","year":2022,"lang":"en","type":"dataset","venue":"Entrepôt pour orphelin","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Organism; Taxon; Identification (biology); Natural (archaeology)","score_opus":0.014042202746072553,"score_gpt":0.28887623982623717,"score_spread":0.27483403708016463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6917719367","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00092061196,0.00398947,0.0000038931425,0.0011091746,0.0009011804,0.00046568582,0.9924328,0.00012584007,0.00005139792],"genre_scores_gemma":[0.000043520515,0.0015899152,0.00007065092,0.0042727976,0.0009256472,0.000102636695,0.98403686,0.000055917197,0.008902081],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979369,0.00010648601,0.00041320207,0.0005396703,0.0005996449,0.00040411024],"domain_scores_gemma":[0.99827796,0.00009257177,0.00020721088,0.0010694753,0.00005286863,0.000299892],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00017611326,0.00039016877,0.00056119316,0.00019238619,0.00012614294,0.00002554964,0.00031749878,0.00025524042,0.99127746],"category_scores_gemma":[0.000099674755,0.00035436862,0.000388486,0.00016370746,0.000050471965,0.000032063537,0.00017416492,0.0007769337,0.22082885],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002152683,0.00056192756,0.000040111354,0.00013653128,0.00033004337,0.0016206935,0.000019987612,0.0000020861569,0.00007261526,0.000010686196,0.9960363,0.000953786],"study_design_scores_gemma":[0.0016586272,0.00015306524,0.00014651634,0.00007576581,0.00047672956,0.00014385258,0.000051229723,0.0000035002097,0.00029805873,0.00012871361,0.99654526,0.00031869358],"about_ca_topic_score_codex":0.00015130626,"about_ca_topic_score_gemma":0.000009189097,"teacher_disagreement_score":0.7704486,"about_ca_system_score_codex":0.00017325756,"about_ca_system_score_gemma":0.0005324822,"threshold_uncertainty_score":0.9998908},"labels":[],"label_agreement":null},{"id":"W6918026401","doi":"10.58067/c6nr-6h76","title":"Fundamentals of Business Math","year":2023,"lang":"en","type":"book","venue":"Conestoga College Repository","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Conestoga College","funders":"","keywords":"Calculus (dental); Business management; Work (physics); Algebra over a field","score_opus":0.018463873809177377,"score_gpt":0.25796400101745487,"score_spread":0.23950012720827749,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6918026401","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.043317012,0.009079055,0.0000188931,0.00015732861,0.003852763,0.0016803634,0.0004082024,0.0005263333,0.94096005],"genre_scores_gemma":[0.018157134,0.00041863942,0.00004123363,0.00015570044,0.0008414314,0.000064694,0.00018559922,0.0001468484,0.9799887],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981592,0.000034554356,0.0005994886,0.00042318756,0.00054266053,0.00024088085],"domain_scores_gemma":[0.9981278,0.00013273278,0.00041460557,0.00077561446,0.00036610872,0.00018314908],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011279786,0.0003598608,0.0009817863,0.00026381126,0.00010131636,0.000010831528,0.00018010559,0.00045256037,0.00011668221],"category_scores_gemma":[0.00002755629,0.00033866346,0.00032591601,0.00023641426,0.00025363723,0.000044607736,0.000086774766,0.0002631815,0.00023580343],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023658315,0.0013147717,0.0014290909,0.010701231,0.0047035664,0.023163471,0.00051010284,0.000010862508,0.02379656,0.041518886,0.88859063,0.0018949672],"study_design_scores_gemma":[0.0072036334,0.0008681682,0.026518509,0.0080986535,0.0030320634,0.0020019573,0.00025105887,0.00007503439,0.012234832,0.00286058,0.9354238,0.0014317125],"about_ca_topic_score_codex":0.000011807474,"about_ca_topic_score_gemma":9.546566e-7,"teacher_disagreement_score":0.04683314,"about_ca_system_score_codex":0.0003151039,"about_ca_system_score_gemma":0.0023563965,"threshold_uncertainty_score":0.99990654},"labels":[],"label_agreement":null},{"id":"W6920352140","doi":"10.60692/3mga5-dwa78","title":"Autophagy in protists and their hosts: When, how and why?","year":2023,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Autophagy; Protist; Intracellular parasite; Protozoa; Model organism; Mechanism (biology); Autophagosome; Organism","score_opus":0.02686929115108009,"score_gpt":0.22170326668140242,"score_spread":0.19483397553032233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920352140","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99736196,0.000040209037,0.00041257803,0.00045056042,0.000094855226,0.00067285437,0.00004051534,0.00023794743,0.00068853906],"genre_scores_gemma":[0.9990743,0.00000259715,0.000034302797,0.00042305505,0.000044886398,0.000105873194,0.000025007688,0.00000921811,0.0002807739],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99931175,0.000030222089,0.00024033379,0.00011385955,0.00012751986,0.00017633261],"domain_scores_gemma":[0.9995735,0.000006945426,0.00008745567,0.00018317958,0.00004792514,0.000100943995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020536232,0.00013106324,0.0002192306,0.0002765946,0.00005361998,0.00009041548,0.00003854674,0.000080577534,0.000010363702],"category_scores_gemma":[0.0000139515405,0.00009266256,0.000026840495,0.00018228668,0.000033207132,0.00038335967,0.000035001744,0.00007132121,0.00009828222],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039833266,0.000008756095,0.6331803,0.0035969072,0.00017099665,0.00011886676,0.349239,0.0000049478285,0.00005580769,0.0008351356,0.0017041941,0.010686739],"study_design_scores_gemma":[0.0040063323,0.00013069638,0.9611851,0.0006316097,0.000022096312,0.00019703929,0.024894355,0.004930029,0.001913337,0.00002594037,0.0018470366,0.00021641512],"about_ca_topic_score_codex":0.000005462386,"about_ca_topic_score_gemma":2.4276628e-7,"teacher_disagreement_score":0.3280048,"about_ca_system_score_codex":0.000040297607,"about_ca_system_score_gemma":0.00002473256,"threshold_uncertainty_score":0.37786692},"labels":[],"label_agreement":null},{"id":"W6920543080","doi":"10.60692/hknjf-y2255","title":"Autophagy and its mediated mitochondrial quality control maintain pollen tube growth and male fertility in Arabidopsis","year":2022,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; University of Ottawa","funders":"","keywords":"Autophagy; Pollen tube; Arabidopsis; Pollen; Crosstalk; Organelle; Organelle biogenesis; Mitochondrion; Biogenesis","score_opus":0.02094413752922463,"score_gpt":0.23997476492795428,"score_spread":0.21903062739872964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920543080","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99689895,0.00007000789,0.00028349494,0.00026092952,0.00022308766,0.00093195215,0.00042633567,0.00010415172,0.00080110045],"genre_scores_gemma":[0.99887633,9.0188576e-7,0.000024485826,0.0006884598,0.000048865764,0.00021151478,0.000056716937,0.0000096846725,0.000083044106],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.998207,0.00029479963,0.00068434805,0.00019838507,0.00036858837,0.0002469124],"domain_scores_gemma":[0.9993095,0.000037049354,0.00019785724,0.00021365179,0.000069424896,0.00017254763],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053674256,0.0001724882,0.00041877342,0.0002438937,0.00016307629,0.00004470838,0.00007556127,0.000085858555,0.00019796201],"category_scores_gemma":[0.00008708729,0.00015339165,0.00006022571,0.00021113243,0.000034998513,0.00030354565,0.00006719708,0.00017675357,0.000033705233],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008456118,0.000057086218,0.91542935,0.0019922648,0.0003591101,0.00012459503,0.07057519,0.000035978042,0.00033379204,0.0020840256,0.000103268714,0.00044924504],"study_design_scores_gemma":[0.0130373845,0.00018274502,0.9703678,0.0000637451,0.000064802,0.0001379356,0.010387406,0.004769449,0.00068866793,0.000012982481,0.00006665484,0.00022043112],"about_ca_topic_score_codex":0.000047253834,"about_ca_topic_score_gemma":4.896095e-7,"teacher_disagreement_score":0.060187783,"about_ca_system_score_codex":0.00014631254,"about_ca_system_score_gemma":0.00007619258,"threshold_uncertainty_score":0.625513},"labels":[],"label_agreement":null},{"id":"W6920581221","doi":"10.60692/hpmgn-nxd12","title":"Autophagy in major human diseases","year":2021,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Grossman; Biological sciences; Research center; Section (typography); Cancer; Medical school; Publishing","score_opus":0.024463391884650295,"score_gpt":0.24994327423306206,"score_spread":0.22547988234841176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920581221","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914212,0.000046025383,0.00039203843,0.00006379266,0.00017250016,0.000248247,0.00006445549,0.00018215504,0.0074095377],"genre_scores_gemma":[0.99837536,2.2819825e-7,0.000050659582,0.0005878957,0.000093976916,0.000053981872,0.00010743334,0.000009531437,0.0007209466],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989776,0.00003981687,0.00044185805,0.0001191374,0.00023353772,0.00018803363],"domain_scores_gemma":[0.9993134,0.0000034325312,0.000102140686,0.00033795965,0.000109929955,0.00013312596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007553116,0.00012476777,0.00024775436,0.00017835076,0.00006925585,0.000058535512,0.0000572305,0.0000729302,0.00026261483],"category_scores_gemma":[0.000013531008,0.00010589568,0.00009522829,0.00023224126,0.000018933213,0.00030436428,0.000027960237,0.00007528358,0.0006664854],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025960413,0.000041155887,0.9552354,0.0016829396,0.00019618009,0.0006962168,0.037494082,0.000028514545,0.00009363794,0.0027719194,0.00050612935,0.0009941758],"study_design_scores_gemma":[0.004137195,0.00004643704,0.9810795,0.0003425697,0.00007424542,0.0001311326,0.0065158466,0.00036232534,0.0065090456,0.000008802806,0.0006236214,0.00016926871],"about_ca_topic_score_codex":0.0000042363067,"about_ca_topic_score_gemma":1.831285e-7,"teacher_disagreement_score":0.030978234,"about_ca_system_score_codex":0.00010594051,"about_ca_system_score_gemma":0.00009506382,"threshold_uncertainty_score":0.85665435},"labels":[],"label_agreement":null},{"id":"W6920833439","doi":"10.6084/m9.figshare.26602936","title":"Additional file 1 of Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; McMaster University; University of Manitoba","funders":"","keywords":"Autophagy; Senescence; Glycolysis; Glioblastoma; Tumor cells; Metabolism","score_opus":0.01774706220372753,"score_gpt":0.2808810288174589,"score_spread":0.2631339666137314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6920833439","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3223106,0.00092448643,8.956949e-8,0.000009474747,0.000008659989,0.0001362335,0.6765244,0.00004471588,0.000041320363],"genre_scores_gemma":[0.6974036,0.000001765401,0.00003836805,0.00003541956,0.000070550304,0.00017827538,0.30206472,0.000016014834,0.00019128548],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.9991863,0.00002395955,0.00022809335,0.00025741608,0.00016272173,0.00014152404],"domain_scores_gemma":[0.99900264,0.0006236304,0.000057928373,0.00014568004,0.000062651605,0.000107480504],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000018080575,0.00012805751,0.00024337952,0.00013941101,0.000054458837,0.00003905569,0.00004943295,0.00006791429,0.82754964],"category_scores_gemma":[0.00021162165,0.000121977755,0.00006106294,0.00021653563,0.0000432112,0.000106983476,0.00004940383,0.000097085795,0.00009514547],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017877122,0.00014779226,0.004074762,0.0026826803,0.00028693362,0.0017245963,0.00029354682,0.000042343683,0.00061876635,0.000017289221,0.98320794,0.006724602],"study_design_scores_gemma":[0.0006126012,0.00018669665,0.92022324,0.008478655,0.000050327573,0.00031275142,0.000029469355,0.0032301664,0.0054216073,0.00013920612,0.06106908,0.000246193],"about_ca_topic_score_codex":0.000007316749,"about_ca_topic_score_gemma":0.00001385189,"teacher_disagreement_score":0.9221388,"about_ca_system_score_codex":0.000028067987,"about_ca_system_score_gemma":0.00009751657,"threshold_uncertainty_score":0.49741083},"labels":[],"label_agreement":null},{"id":"W6929483853","doi":"10.48550/arxiv.2311.15687","title":"Auditory cortex and beyond: Deficits in congenital amusia","year":2023,"lang":"en","type":"preprint","venue":"arXiv (Cornell University)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Automotive Partnership Council","funders":"","keywords":"Cognitive neuroscience of music; Auditory cortex; Perception; Pitch (Music); Cognition; Auditory perception; Pitch perception","score_opus":0.05956760047760727,"score_gpt":0.21149502009928076,"score_spread":0.1519274196216735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6929483853","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99442357,0.00038704296,0.00020088344,0.00007328335,0.0006787071,0.00041865726,0.00005622008,0.00018279474,0.0035788647],"genre_scores_gemma":[0.9938933,0.0009563361,0.000020547312,0.00021048663,0.00020272219,0.0000018730598,0.0000887134,0.000042937816,0.004583065],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99868953,0.000054028576,0.00017865538,0.0007124745,0.00008284891,0.00028247712],"domain_scores_gemma":[0.9990317,0.00008121921,0.00011137701,0.0004892984,0.00006834512,0.00021801236],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010619938,0.00026906325,0.00042573674,0.000341963,0.000056405577,0.000018117627,0.00017901445,0.00034370882,0.000120816716],"category_scores_gemma":[0.000029008912,0.00030932654,0.00014564881,0.0002796396,0.00017052259,0.00007188921,0.00037558787,0.00056599936,0.0001675581],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006831338,0.0032995313,0.73500746,0.0033263136,0.0058393106,0.09967337,0.0049742474,0.016658282,0.004707411,0.09516042,0.018832317,0.0056899735],"study_design_scores_gemma":[0.0054423274,0.00028069757,0.9441299,0.0003914434,0.0008448276,0.00003723128,0.0010195446,0.018277403,0.00016385477,0.027324853,0.0011651185,0.00092278875],"about_ca_topic_score_codex":0.00015102797,"about_ca_topic_score_gemma":0.00011985886,"teacher_disagreement_score":0.20912242,"about_ca_system_score_codex":0.00015329372,"about_ca_system_score_gemma":0.00024317384,"threshold_uncertainty_score":0.99993587},"labels":[],"label_agreement":null},{"id":"W6929848320","doi":"10.5061/dryad.brv15dv5z","title":"Depot-specific analysis of human adipose cells and their responses to Bisphenol S","year":2020,"lang":"en","type":"dataset","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; Health Canada","funders":"","keywords":"Nucleofection; Articular cartilage damage; Fusible alloy; TSG101","score_opus":0.0425664388426434,"score_gpt":0.28271838921095765,"score_spread":0.24015195036831427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6929848320","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0172102,0.0004914304,0.00014829607,0.0002525053,0.000045170014,0.00065472274,0.9800596,0.00022113702,0.00091688713],"genre_scores_gemma":[0.030689023,0.000924969,0.00004502457,0.0004931497,0.00014405012,8.5581036e-8,0.96664345,0.00080068404,0.00025954022],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.998092,0.00032424254,0.00039039925,0.00056025514,0.00036180427,0.0002713192],"domain_scores_gemma":[0.99815756,0.00004650879,0.00017981017,0.0008325522,0.0003613952,0.0004221633],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00030992905,0.00025299747,0.0005753136,0.0008551234,0.0006783431,0.00021178658,0.00065057684,0.00012979443,0.0120238755],"category_scores_gemma":[0.00022454813,0.00023005722,0.00016238049,0.001417842,0.0002162446,0.00005755694,0.00079151266,0.00033256476,0.0025130163],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053875503,0.0001944256,0.0000010551107,0.00016543285,0.0012291324,0.00006621593,0.00052769756,0.0000036500699,0.019015387,0.000049880713,0.9717651,0.006443253],"study_design_scores_gemma":[0.0005075199,0.0007529623,0.0007151569,0.00006954619,0.00064659846,0.000016001242,0.00016779726,0.000015354923,0.002905792,0.000012746488,0.993995,0.00019548803],"about_ca_topic_score_codex":0.000020583157,"about_ca_topic_score_gemma":6.0717804e-7,"teacher_disagreement_score":0.022229921,"about_ca_system_score_codex":0.000075077915,"about_ca_system_score_gemma":0.000008990736,"threshold_uncertainty_score":0.99826366},"labels":[],"label_agreement":null},{"id":"W6930049307","doi":"10.5281/zenodo.10668331","title":"Fig. 2. Prevalence estimates and 95 in Evidence for intercontinental parasite exchange through molecular detection and characterization of haematozoa in northern pintails (Anas acuta) sampled throughout the North Pacific Basin","year":2015,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Wildlife refuge; Wildlife; Confidence interval; Parasite hosting; Wildlife conservation","score_opus":0.046142494185812157,"score_gpt":0.3102648557979779,"score_spread":0.26412236161216573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930049307","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98153895,0.00466248,0.0027994171,0.0005064338,0.00009529994,0.0038615987,0.0008952515,0.00032665321,0.0053139264],"genre_scores_gemma":[0.9885049,0.005405711,0.00017634967,0.00012924742,0.00010729251,0.0000022332601,0.0018375788,0.002040731,0.0017959846],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986215,0.00019953852,0.00029928633,0.00040544692,0.0002503941,0.00022380069],"domain_scores_gemma":[0.99912536,0.000036136174,0.00023157326,0.00033070432,0.00019962658,0.000076608274],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003461753,0.00020951718,0.00033855787,0.00018853424,0.00016206452,0.00011378429,0.0002465376,0.00011008255,0.00061906053],"category_scores_gemma":[0.0003897473,0.00017820451,0.00004056474,0.00032988272,0.00019965148,0.00020055388,0.00023539392,0.00018865435,0.000046972124],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01582759,0.0038312275,0.049962834,0.038852006,0.0026309816,0.0007394997,0.112973236,0.000032233176,0.29073757,0.0012353094,0.083748735,0.39942876],"study_design_scores_gemma":[0.009913166,0.0026600738,0.17242827,0.008528431,0.0005847911,0.0005292414,0.0020315275,0.002577065,0.0052402774,0.00048937823,0.7937576,0.0012601418],"about_ca_topic_score_codex":0.00010015389,"about_ca_topic_score_gemma":0.000065079126,"teacher_disagreement_score":0.7100089,"about_ca_system_score_codex":0.00008933275,"about_ca_system_score_gemma":0.000009539561,"threshold_uncertainty_score":0.7266969},"labels":[],"label_agreement":null},{"id":"W6930124137","doi":"10.5061/dryad.g2t6204","title":"Data from: Impacts of dead-wood manipulation on the biodiversity of temperate and boreal forests - A systematic review","year":2019,"lang":"en","type":"dataset","venue":"Data Archiving and Networked Services (DANS)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Biodiversity; Species richness; Abundance (ecology); Taiga; Temperate rainforest; Habitat; Boreal; Temperate forest","score_opus":0.05400112397635414,"score_gpt":0.30524533972567647,"score_spread":0.2512442157493223,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930124137","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.112766966,0.017920824,0.000005411108,0.00008083494,0.000065521395,0.0011319862,0.86800563,0.000010554625,0.000012251038],"genre_scores_gemma":[0.043109454,0.036987297,0.00002178479,0.0006061536,0.00008827827,0.0000061607616,0.9191636,0.0000127830635,0.0000045276624],"study_design_codex":"not_applicable","study_design_gemma":"systematic_review","domain_scores_codex":[0.9979584,0.000328334,0.00056504714,0.00057389855,0.00036451072,0.00020977431],"domain_scores_gemma":[0.9948744,0.0005910597,0.0006898182,0.0036840073,0.000037911635,0.00012280163],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007660474,0.0003213068,0.0010891987,0.00007744346,0.00010620477,0.000032242337,0.0013886464,0.000111297406,0.000025579076],"category_scores_gemma":[0.00006092511,0.00019550681,0.000053009382,0.0001367859,0.000101709986,0.00018626203,0.0010956809,0.0002686294,0.000012907799],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004939206,0.00019172778,0.0063548773,0.41097325,0.0014706143,0.000028806791,0.0002631673,0.000003889859,0.000027227221,0.0000052834507,0.5800924,0.00009488401],"study_design_scores_gemma":[0.0028971245,0.00076991174,0.17850155,0.7609878,0.017640883,0.00007061414,0.0004616033,0.02513307,0.000035439654,0.00016181181,0.012386445,0.0009537105],"about_ca_topic_score_codex":0.0024907712,"about_ca_topic_score_gemma":0.001305965,"teacher_disagreement_score":0.5677059,"about_ca_system_score_codex":0.000010635652,"about_ca_system_score_gemma":0.000063842956,"threshold_uncertainty_score":0.7972536},"labels":[],"label_agreement":null},{"id":"W6930315438","doi":"10.5281/zenodo.12571621","title":"Implementation of the Entrepreneurship Education Curriculum: The Panacea to National Development","year":2024,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Panacea (medicine); Vocational education; Government (linguistics); Entrepreneurship; National development; Curriculum; Sustainable development; Meaning (existential)","score_opus":0.02847074942768124,"score_gpt":0.31633792428684276,"score_spread":0.2878671748591615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930315438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9568523,0.0005027221,0.00073648477,0.009966557,0.00037829636,0.0013607168,0.00007550123,0.00034735762,0.029780038],"genre_scores_gemma":[0.9978919,0.000022617363,0.00008175614,0.00056771433,0.000128599,2.750065e-7,0.00029742066,0.00020936383,0.00080032804],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989798,0.00011881202,0.00017559553,0.00018078332,0.0004190798,0.00012591796],"domain_scores_gemma":[0.99927,0.000015462347,0.000041289284,0.00020827272,0.00039199146,0.00007295322],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0003613671,0.00006834118,0.000059675967,0.00010417993,0.00060655584,0.00014723271,0.00030718214,0.000019623261,0.0052253576],"category_scores_gemma":[0.0001264032,0.00004435197,0.00004493977,0.0005092086,0.000047741167,0.00007013219,0.00022074056,0.00010418543,0.0011935186],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050093084,0.00033241257,0.00039824878,0.00018458425,0.00018992936,0.0000029625942,0.00720003,0.000027920825,0.009062148,0.028344164,0.34341985,0.61078763],"study_design_scores_gemma":[0.00017995776,0.00006231772,0.031285554,0.00007516476,0.00002583883,0.000038508915,0.0010553638,0.00004420179,0.009344073,0.00030533012,0.9575251,0.000058634527],"about_ca_topic_score_codex":0.000014289336,"about_ca_topic_score_gemma":5.930432e-7,"teacher_disagreement_score":0.61410517,"about_ca_system_score_codex":0.00015775143,"about_ca_system_score_gemma":0.000061928295,"threshold_uncertainty_score":0.99958414},"labels":[],"label_agreement":null},{"id":"W6930330019","doi":"10.5281/zenodo.13235050","title":"JuliaGPU/GPUCompiler.jl: v0.27.0","year":2024,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Perimeter Institute","funders":"","keywords":"Set (abstract data type); Function (biology); Software; Closed set","score_opus":0.03201978788812003,"score_gpt":0.2813891993250766,"score_spread":0.24936941143695657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930330019","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00008660672,0.0032697385,0.00025576653,0.00095189235,0.0004810381,0.00070846366,0.00055038877,0.0032790336,0.99041706],"genre_scores_gemma":[0.0039146836,0.0010503937,0.00016320198,0.0007047073,0.0013857841,7.991222e-8,0.0040345406,0.020105412,0.9686412],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979808,0.00015247773,0.00026785076,0.0006486839,0.0005306899,0.0004194959],"domain_scores_gemma":[0.99851686,0.000009163399,0.00011911489,0.0008181416,0.0001982297,0.00033849254],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002678002,0.0003080566,0.00036758004,0.000522319,0.00038615157,0.00039039197,0.0006407014,0.00024260592,0.2016403],"category_scores_gemma":[0.00015111918,0.0002926833,0.00016998172,0.0004889291,0.00019235967,0.00005381142,0.0006343798,0.0005787958,0.1874709],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007251221,0.00016115344,5.2852886e-7,0.00041827463,0.000310168,0.00021660615,0.00020008559,3.965337e-7,0.00027744062,0.0017964022,0.9721234,0.024423046],"study_design_scores_gemma":[0.00070729805,0.00026408955,0.000042862364,0.00044554766,0.0001474529,0.00021222542,0.000064939355,0.00002834717,0.00012942746,0.00028249543,0.9974051,0.00027017426],"about_ca_topic_score_codex":0.0000186015,"about_ca_topic_score_gemma":2.0421395e-7,"teacher_disagreement_score":0.025281753,"about_ca_system_score_codex":0.00013641114,"about_ca_system_score_gemma":0.000010795151,"threshold_uncertainty_score":0.99995255},"labels":[],"label_agreement":null},{"id":"W6930383516","doi":"10.5281/zenodo.1319688","title":"Productive Capabilities: A Framework For Vocational Education","year":2018,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Vocational education; Work (physics); Apprenticeship; Order (exchange)","score_opus":0.03184613818385675,"score_gpt":0.3088589740162825,"score_spread":0.27701283583242575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930383516","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.44925663,0.0009601308,0.11750302,0.01722155,0.0016085323,0.007554423,0.00082331145,0.0028683585,0.40220404],"genre_scores_gemma":[0.9850807,0.000031283726,0.005735217,0.0010538511,0.0020326893,7.863292e-7,0.001839649,0.00089939055,0.0033263909],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989485,0.00008354491,0.00016924106,0.0003430759,0.00023254534,0.00022305897],"domain_scores_gemma":[0.99795747,0.00003505725,0.00006898726,0.00040489872,0.0013832713,0.00015033945],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0003045637,0.00010085451,0.00011538337,0.00013254493,0.0011583157,0.00014083063,0.00026010323,0.00006175489,0.0102938935],"category_scores_gemma":[0.001378534,0.00010007982,0.00005620599,0.00030007836,0.00026493016,0.00013804346,0.00011752938,0.00013138726,0.0025427868],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010847404,0.0013654549,0.000018086424,0.00031161768,0.00022244426,0.0000020192053,0.008576782,0.0000015471461,0.0054357233,0.21644177,0.3317115,0.4348283],"study_design_scores_gemma":[0.00051947014,0.00072180957,0.0029967558,0.00007709922,0.000036118556,0.000058929247,0.0010199407,0.00005588688,0.003614316,0.020329233,0.97044516,0.00012528732],"about_ca_topic_score_codex":0.0000049259725,"about_ca_topic_score_gemma":5.351145e-8,"teacher_disagreement_score":0.6387336,"about_ca_system_score_codex":0.00015328488,"about_ca_system_score_gemma":0.00003605856,"threshold_uncertainty_score":0.99823385},"labels":[],"label_agreement":null},{"id":"W6930420880","doi":"10.5281/zenodo.12571069","title":"dockstore/dockstore: 1.15.3","year":2024,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"Duration (music); Test (biology); Relation (database); Window (computing); Redundancy (engineering)","score_opus":0.02642516767774526,"score_gpt":0.27486480321947165,"score_spread":0.2484396355417264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930420880","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00007904597,0.0046022288,0.00022666674,0.0005910661,0.00041375417,0.0006714102,0.0004572033,0.0032926165,0.989666],"genre_scores_gemma":[0.007614331,0.0010164245,0.0001459184,0.00062846846,0.0016425904,1.1343515e-7,0.003881,0.022648823,0.9624223],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99804425,0.00013804097,0.00024892006,0.00063552085,0.0005247228,0.00040851888],"domain_scores_gemma":[0.998542,0.00000787316,0.0001162522,0.00081430475,0.00018190495,0.00033764477],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00024835128,0.00030173396,0.00034843525,0.00054689497,0.00043147008,0.00034416906,0.0006030143,0.00024648232,0.2113492],"category_scores_gemma":[0.00015861071,0.00028510654,0.00016794108,0.00047511247,0.00019125686,0.00005416565,0.00058519386,0.00054830906,0.12527855],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006859764,0.00013754414,4.3831542e-7,0.00039723798,0.00029838487,0.0002345424,0.00023988553,3.0465918e-7,0.00031992057,0.0032451523,0.9709513,0.024106702],"study_design_scores_gemma":[0.000648098,0.0002519345,0.000028961074,0.00040286733,0.00015126803,0.0002485519,0.00006462013,0.00001635864,0.0001271489,0.00035970265,0.99743515,0.0002653458],"about_ca_topic_score_codex":0.000022467832,"about_ca_topic_score_gemma":1.7995083e-7,"teacher_disagreement_score":0.08607066,"about_ca_system_score_codex":0.00019086828,"about_ca_system_score_gemma":0.0000114666145,"threshold_uncertainty_score":0.9999601},"labels":[],"label_agreement":null},{"id":"W6930479133","doi":"10.5281/zenodo.13651811","title":"Fig. 2 in New genus of dimeropygid trilobites from the earliest Ordovician of Laurentia","year":2006,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Laurentia; Ordovician; Cove; Section (typography); Genus; Subgenus; Trilobite","score_opus":0.020975009997394163,"score_gpt":0.2475011933196716,"score_spread":0.22652618332227745,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930479133","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.015601162,0.008065155,0.00027929424,0.0008319452,0.00018562829,0.001400988,0.002137237,0.00050506153,0.9709935],"genre_scores_gemma":[0.39219502,0.0027188696,0.0008859114,0.0009137036,0.0033390562,2.0225873e-7,0.02792915,0.021678658,0.5503394],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99865127,0.00017943923,0.00032731623,0.00027655705,0.00035732178,0.00020810298],"domain_scores_gemma":[0.9989006,0.000028345157,0.00025628746,0.00058849173,0.00012871526,0.000097597345],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00016084687,0.00017165381,0.00034607534,0.0002514943,0.00013868166,0.00004929652,0.0005835955,0.00013820888,0.038532004],"category_scores_gemma":[0.00017184827,0.0001388465,0.00009956322,0.00044805577,0.00018604189,0.00003218592,0.00027092264,0.00025763782,0.0010374866],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015478944,0.00023684022,0.000098115386,0.00008827678,0.00017879343,0.000018992858,0.0003817435,0.0000026372581,0.00154386,0.00039353155,0.96849245,0.028409954],"study_design_scores_gemma":[0.0012122077,0.00019376517,0.0053285956,0.00033092516,0.000086154425,0.000006226398,0.00007758548,0.0000096563335,0.00053452415,0.00007794065,0.992029,0.00011343242],"about_ca_topic_score_codex":0.0016725997,"about_ca_topic_score_gemma":0.0000311242,"teacher_disagreement_score":0.42065412,"about_ca_system_score_codex":0.000041797073,"about_ca_system_score_gemma":0.000021829219,"threshold_uncertainty_score":0.9997403},"labels":[],"label_agreement":null},{"id":"W6931028258","doi":"10.5281/zenodo.6159980","title":"Epimicta Foerster","year":2013,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Ovipositor; Depression (economics); Head (geology); Genus; Wing; Margin (machine learning)","score_opus":0.03064204254476581,"score_gpt":0.2537949941771207,"score_spread":0.22315295163235488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931028258","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.47747996,0.00027755048,0.0017988308,0.004984099,0.00014381453,0.0011930882,0.000063605396,0.001479177,0.51257986],"genre_scores_gemma":[0.9916862,0.00007094295,0.00022965854,0.001287647,0.00018789904,5.871015e-8,0.0006656054,0.0009779255,0.0048940443],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99901664,0.00009117853,0.00015407025,0.00024173083,0.00023508862,0.0002612765],"domain_scores_gemma":[0.999008,0.000009918834,0.000042319185,0.00038950038,0.00032556502,0.00022471258],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001553462,0.00009766689,0.00012159966,0.00012108015,0.00070620055,0.00026078115,0.00030987346,0.000048353588,0.08856142],"category_scores_gemma":[0.00014187624,0.000089588306,0.0000612071,0.00023633629,0.000096392214,0.0001757447,0.0002867036,0.0001613493,0.04363853],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013100644,0.0003462021,0.000033306478,0.000087264416,0.00015764605,0.000045812103,0.00096403994,0.0000042289935,0.027386371,0.0028474526,0.7713709,0.19662575],"study_design_scores_gemma":[0.00089454866,0.00025380685,0.006436713,0.000027299775,0.000024949106,0.00013752654,0.00018725169,0.00022869352,0.0019830829,0.0003924713,0.98931736,0.00011630343],"about_ca_topic_score_codex":0.000010677403,"about_ca_topic_score_gemma":1.7336143e-8,"teacher_disagreement_score":0.51420623,"about_ca_system_score_codex":0.00006679552,"about_ca_system_score_gemma":0.0000027971353,"threshold_uncertainty_score":0.9571061},"labels":[],"label_agreement":null},{"id":"W6931086742","doi":"10.5281/zenodo.5181388","title":"MS8 Choice of Vocabulary Publication platform for SSHOC","year":2021,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canarie","funders":"","keywords":"Metadata; Vocabulary; Milestone; Ontology; Controlled vocabulary; License; Set (abstract data type); Table (database); Publishing","score_opus":0.05383678186092796,"score_gpt":0.29599230563326906,"score_spread":0.2421555237723411,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931086742","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5890738,0.002428437,0.02571182,0.010704247,0.00041174344,0.0032087853,0.0011941195,0.001989468,0.3652776],"genre_scores_gemma":[0.9845705,0.00020968926,0.00087141444,0.0009201847,0.00030546906,2.1325056e-7,0.0075335912,0.0010271143,0.00456182],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989543,0.00005674371,0.00023983707,0.000266839,0.00026625782,0.00021603935],"domain_scores_gemma":[0.9980198,0.000035716137,0.0000976395,0.00044110688,0.0012510124,0.00015472028],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00027996668,0.00009200587,0.00016104651,0.00012816976,0.0005283319,0.0001255127,0.0002692901,0.00006267254,0.009627241],"category_scores_gemma":[0.0010166272,0.0000944676,0.00008594734,0.00041647072,0.000078721474,0.00018586572,0.00021960629,0.00012170795,0.00080501434],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007862194,0.0013914932,0.0000833611,0.00082765945,0.00049675757,0.000044082593,0.0014337633,0.00001566877,0.119440205,0.028277058,0.4585595,0.38864422],"study_design_scores_gemma":[0.0014282843,0.0002796057,0.0027332513,0.00004376157,0.00004765049,0.00007329487,0.00015697957,0.00032145737,0.029981317,0.00029468807,0.9645423,0.00009736745],"about_ca_topic_score_codex":0.000003910293,"about_ca_topic_score_gemma":1.0805049e-7,"teacher_disagreement_score":0.5059828,"about_ca_system_score_codex":0.00007462786,"about_ca_system_score_gemma":0.000016850838,"threshold_uncertainty_score":0.999973},"labels":[],"label_agreement":null},{"id":"W6931239652","doi":"10.5281/zenodo.14980973","title":"Fig. 51 in A revision of the genus Sclerocoelus Marshall (Diptera: Sphaeroceridae)","year":2025,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Aedeagus; Genus; Scale (ratio); Taxonomy (biology); Male genitalia","score_opus":0.02225678642731423,"score_gpt":0.26010925311278726,"score_spread":0.23785246668547302,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931239652","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0023577877,0.0025134892,0.00020459338,0.0006190299,0.00016769044,0.0013304258,0.0003512149,0.00040440971,0.99205136],"genre_scores_gemma":[0.27905798,0.005263633,0.00033217456,0.0015171664,0.00066315505,1.8069058e-7,0.002079768,0.010128494,0.7009575],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.998409,0.00022859291,0.00031469934,0.00038400514,0.00040084228,0.0002628919],"domain_scores_gemma":[0.9987389,0.000012398968,0.00019409148,0.00074773584,0.00020212887,0.00010475367],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000269437,0.00020026453,0.0003396722,0.00036160983,0.0002650014,0.00007663461,0.00074516033,0.0001712012,0.050286047],"category_scores_gemma":[0.00030441786,0.00016284196,0.00012685893,0.00060994364,0.00014116016,0.000037459144,0.0007530772,0.0003723333,0.0017904445],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017591356,0.00024011428,0.000016570106,0.0006668416,0.00012404061,0.000040475268,0.00025443995,0.000002441748,0.00041008228,0.00075549533,0.80192626,0.19538732],"study_design_scores_gemma":[0.0010836544,0.000113513524,0.0016073771,0.001442875,0.000051860734,0.000025452377,0.00003994577,0.000027650345,0.00022114904,0.000036548674,0.9952227,0.0001272774],"about_ca_topic_score_codex":0.000054246535,"about_ca_topic_score_gemma":0.0000010470196,"teacher_disagreement_score":0.2910939,"about_ca_system_score_codex":0.00012851834,"about_ca_system_score_gemma":0.000021803531,"threshold_uncertainty_score":0.9989868},"labels":[],"label_agreement":null},{"id":"W6931246917","doi":"10.5281/zenodo.5834182","title":"tobiste/PlateTectonicStressR: PlateTectonicStressR 1.1 release","year":2022,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Stress (linguistics); Orientation (vector space); Intraplate earthquake; Motion (physics); Relative motion; Component (thermodynamics)","score_opus":0.021945922513042396,"score_gpt":0.25278962063431726,"score_spread":0.23084369812127487,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931246917","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018462702,0.002837555,0.00005070936,0.00033234857,0.00024622327,0.0010625595,0.0014810277,0.0030285458,0.98911476],"genre_scores_gemma":[0.058251463,0.004155528,0.00028372582,0.0013086669,0.0011827191,8.0734935e-7,0.0303361,0.039666746,0.8648142],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973525,0.00027417377,0.00033918515,0.00077277323,0.0006959136,0.0005654814],"domain_scores_gemma":[0.99796665,0.000020431487,0.0002571603,0.001172408,0.00017172757,0.00041160078],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00027487692,0.00037497943,0.0004518248,0.000564746,0.0012916322,0.00025348013,0.0009279792,0.0002507773,0.400435],"category_scores_gemma":[0.00024838967,0.00039489483,0.00020722288,0.0005514794,0.00020442369,0.00006748649,0.0010906091,0.00089269044,0.011396037],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027701884,0.00029546345,0.0000016226411,0.00028654851,0.00037870675,0.00045218266,0.00017434292,0.0000065961294,0.0007217653,0.0006877186,0.9539978,0.04272022],"study_design_scores_gemma":[0.0016470307,0.0004300976,0.0000705925,0.00015949243,0.00013235625,0.00036422967,0.0001260889,0.000055286677,0.00027266183,0.000059818783,0.99631804,0.0003643267],"about_ca_topic_score_codex":0.000048217298,"about_ca_topic_score_gemma":6.4258796e-7,"teacher_disagreement_score":0.38903895,"about_ca_system_score_codex":0.00035616488,"about_ca_system_score_gemma":0.0000228041,"threshold_uncertainty_score":0.9998503},"labels":[],"label_agreement":null},{"id":"W6931487259","doi":"10.5281/zenodo.4401223","title":"FIGURES 35–38. Paragrallomyia pseudoalbibasis n in A redefinition of Paragrallomyia Hendel (Diptera: Micropezidae, Taeniapterinae) and a revision of the P. albibasis complex","year":2020,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Dorsum; Fork (system call); Dorsal fin","score_opus":0.04065099731134313,"score_gpt":0.2638440032786553,"score_spread":0.22319300596731217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931487259","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06279876,0.0069207675,0.00032270292,0.0032705984,0.00017785885,0.003950944,0.0020258536,0.0007693402,0.91976315],"genre_scores_gemma":[0.9671701,0.0062047793,0.0012382424,0.00062073587,0.00025897817,3.0733446e-7,0.0021152883,0.0043822024,0.018009353],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99795866,0.000358878,0.00050509686,0.00047703504,0.00043874458,0.00026159923],"domain_scores_gemma":[0.99869746,0.000024526353,0.00040214692,0.00060714,0.00011532056,0.00015343112],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002520222,0.00027532785,0.00056416466,0.00039071226,0.00023586146,0.00007490139,0.00053918926,0.0001717364,0.013233628],"category_scores_gemma":[0.0002195586,0.00022610133,0.00016089612,0.00064541725,0.0003196798,0.00004850202,0.0005832853,0.00033515293,0.00020729599],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008676979,0.00048369213,0.000112216694,0.0020136854,0.00038992832,0.000073826566,0.0011282056,0.000002506029,0.009599231,0.0015939786,0.89258224,0.091152824],"study_design_scores_gemma":[0.0015136898,0.00034392506,0.0033042743,0.0012840127,0.000096139935,0.00008506209,0.00010691389,0.000061035,0.00079329,0.000060891143,0.99215466,0.00019612335],"about_ca_topic_score_codex":0.00011647056,"about_ca_topic_score_gemma":0.000001847422,"teacher_disagreement_score":0.9043714,"about_ca_system_score_codex":0.000056630226,"about_ca_system_score_gemma":0.000012846354,"threshold_uncertainty_score":0.9876684},"labels":[],"label_agreement":null},{"id":"W6931704363","doi":"10.5281/zenodo.5897495","title":"FIG. 5 in Biological and cultural history of domesticated dogs in the Americas","year":2022,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Hairless; Domestication; White (mutation); Labrador Retriever; Native american","score_opus":0.05164294409798013,"score_gpt":0.28737614912556686,"score_spread":0.23573320502758674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931704363","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.025370885,0.0044438243,0.0000103896555,0.00060922734,0.00006848558,0.0008405611,0.00015247248,0.00021318528,0.968291],"genre_scores_gemma":[0.79327506,0.008320755,0.00016460236,0.0017457807,0.0003075774,7.413632e-7,0.007518755,0.005771472,0.18289524],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.998905,0.00034585182,0.00016710888,0.00023028004,0.00019917269,0.00015256702],"domain_scores_gemma":[0.99953747,0.000020323765,0.00009283227,0.00025445255,0.00004164382,0.00005325837],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00027403855,0.00010625036,0.00020733323,0.00024947478,0.000087001485,0.000021312293,0.0003330775,0.00006946026,0.08759492],"category_scores_gemma":[0.00024123382,0.00007571412,0.000032740085,0.00031086663,0.00028205346,0.000020571528,0.0002671205,0.00031079282,0.00035087435],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019623859,0.0003635908,0.0001125631,0.00009652936,0.00005152185,0.00017375787,0.002653525,9.2480695e-7,0.0007079016,0.00066851027,0.9778086,0.017166354],"study_design_scores_gemma":[0.00069574645,0.0002629098,0.0051254956,0.000042982345,0.000012571873,0.00007416933,0.00037822413,0.000013681775,0.0000028258216,0.000027845823,0.99328536,0.00007819684],"about_ca_topic_score_codex":0.0000672892,"about_ca_topic_score_gemma":4.5182142e-7,"teacher_disagreement_score":0.78539574,"about_ca_system_score_codex":0.00019876503,"about_ca_system_score_gemma":0.000007471746,"threshold_uncertainty_score":0.9132391},"labels":[],"label_agreement":null},{"id":"W6939183564","doi":"10.60692/749n6-9rx61","title":"Blockade of Uttroside B-Induced Autophagic Pro-Survival Signals Augments Its Chemotherapeutic Efficacy Against Hepatocellular Carcinoma","year":2022,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Autophagy; Bafilomycin; Apoptosis; Hepatocellular carcinoma; Blockade; Chloroquine; Cytotoxicity; Cancer cell","score_opus":0.05664768846057101,"score_gpt":0.251053576676268,"score_spread":0.194405888215697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6939183564","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957919,0.00005488576,0.00025748968,0.00005460792,0.0004016403,0.0014971759,0.00012248197,0.00021052266,0.0016092914],"genre_scores_gemma":[0.9987921,3.5870931e-7,0.000027770673,0.0004531815,0.00009497088,0.00022086696,0.000087765206,0.00003315457,0.0002898162],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974615,0.00015301099,0.00094172754,0.00022385544,0.00086505956,0.00035482977],"domain_scores_gemma":[0.9985434,0.000012518414,0.0005583931,0.0005277022,0.00017751336,0.00018051261],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042195644,0.00028388406,0.00055124005,0.00032140533,0.0002296311,0.000038031863,0.00023313884,0.00009596883,0.00024320043],"category_scores_gemma":[0.000011633833,0.00025352326,0.00023638693,0.00038804696,0.00002574506,0.00023411211,0.000094792515,0.00021047403,0.00020389816],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0045065912,0.00042502637,0.7319031,0.0065040747,0.0025228339,0.00029656565,0.19593741,0.0014758819,0.052077614,0.00042922096,0.000146616,0.0037750672],"study_design_scores_gemma":[0.020823138,0.0011246529,0.27999914,0.00045318302,0.000545128,0.00019418937,0.015330687,0.042107217,0.6380035,0.0000034635825,0.00056529464,0.0008503716],"about_ca_topic_score_codex":0.0000051644793,"about_ca_topic_score_gemma":8.966176e-9,"teacher_disagreement_score":0.58592594,"about_ca_system_score_codex":0.00026168316,"about_ca_system_score_gemma":0.00019254454,"threshold_uncertainty_score":0.9999917},"labels":[],"label_agreement":null},{"id":"W6939807176","doi":"10.6084/m9.figshare.29604845","title":"Additional file 1 of Targeting autophagy and plasminogen activator inhibitor-1 increases survival and remodels the tumor microenvironment in glioblastoma","year":2025,"lang":"en","type":"article","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Glioblastoma; Autophagy; Tumor microenvironment; Plasminogen activator; Activator (genetics); Tumor cells","score_opus":0.010030470148393733,"score_gpt":0.230094950429938,"score_spread":0.22006448028154427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6939807176","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.18916309,0.0005679293,6.2578295e-8,0.000051260486,0.000007796237,0.0002018153,0.80955124,0.000013488404,0.00044329782],"genre_scores_gemma":[0.6719957,0.000016200349,0.00014989015,0.0005768527,0.00013847319,0.0005907798,0.32592794,0.000022504344,0.0005816893],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993428,0.00004001977,0.0001708463,0.0001854721,0.00012908956,0.00013177229],"domain_scores_gemma":[0.9988347,0.00089074206,0.00007331112,0.000121476325,0.000021399903,0.00005834008],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00002670354,0.00011204721,0.00018112459,0.00006378867,0.0000594691,0.000010056636,0.000053869,0.000044828328,0.78157395],"category_scores_gemma":[0.000748564,0.00008580473,0.00003524818,0.00009657402,0.000032876782,0.000056818204,0.00009876015,0.000108487344,0.000032737156],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001596397,0.00009244258,0.00006299335,0.00014307679,0.00003895923,0.000035890134,0.00003824738,0.0000015806258,0.001253748,0.0000058206465,0.99713403,0.0010335945],"study_design_scores_gemma":[0.0029001366,0.00032502337,0.25454664,0.011044751,0.000057424415,0.000066058456,0.00058312604,0.001134725,0.09081736,0.00023869814,0.637942,0.0003440398],"about_ca_topic_score_codex":0.000007850685,"about_ca_topic_score_gemma":0.000003726002,"teacher_disagreement_score":0.7815412,"about_ca_system_score_codex":0.000032091324,"about_ca_system_score_gemma":0.00010467976,"threshold_uncertainty_score":0.34990153},"labels":[],"label_agreement":null},{"id":"W6958183832","doi":"10.6084/m9.figshare.29604851.v1","title":"Additional file 3 of Targeting autophagy and plasminogen activator inhibitor-1 increases survival and remodels the tumor microenvironment in glioblastoma","year":2025,"lang":"en","type":"article","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Glioblastoma; Autophagy; Tumor microenvironment; Plasminogen activator; Activator (genetics); Tumor cells","score_opus":0.009867472126617038,"score_gpt":0.2297813828158426,"score_spread":0.21991391068922556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6958183832","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.19033569,0.0005711049,6.295905e-8,0.000051040606,0.000007873928,0.00020189495,0.80837274,0.000013476767,0.00044610104],"genre_scores_gemma":[0.67689234,0.000016424025,0.00014806021,0.00057612115,0.0001399971,0.0005794967,0.3210323,0.000022491662,0.0005927714],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993428,0.00003998128,0.00017092223,0.0001853913,0.0001291158,0.00013176216],"domain_scores_gemma":[0.9988426,0.00088287255,0.00007332249,0.00012129407,0.000021588367,0.00005833498],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000026691458,0.000112031456,0.00018114306,0.0000637674,0.000059463993,0.000010077269,0.00005383516,0.00004482452,0.77729607],"category_scores_gemma":[0.0007483634,0.00008578289,0.000035245932,0.00009653824,0.000032879117,0.000056861867,0.00009868887,0.0001084652,0.000033094664],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016159649,0.00009297355,0.00006347138,0.00014642028,0.000039169205,0.00003654846,0.000038487382,0.000001590967,0.0012647009,0.000005820289,0.9970939,0.0010553064],"study_design_scores_gemma":[0.0029071486,0.0003209166,0.25024402,0.010897376,0.0000562684,0.000064706124,0.00057383167,0.001123742,0.09170675,0.00023670094,0.6415283,0.00034020536],"about_ca_topic_score_codex":0.00000793968,"about_ca_topic_score_gemma":0.0000037512882,"teacher_disagreement_score":0.777263,"about_ca_system_score_codex":0.00003221848,"about_ca_system_score_gemma":0.00010473757,"threshold_uncertainty_score":0.34981248},"labels":[],"label_agreement":null},{"id":"W6958245272","doi":"10.60692/qxt0t-6t249","title":"Beclin1 restricts RNA virus infection in plants through suppression and degradation of the viral polymerase","year":2018,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Agriculture and Agri-Food Canada","funders":"","keywords":"Autophagy; Virus; RNA; Viral structural protein; Polymerase; Mutant; Intracellular; Viral protein","score_opus":0.030454127636750244,"score_gpt":0.2576262244630193,"score_spread":0.22717209682626907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6958245272","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973194,0.000013918151,0.0006983027,0.000030771054,0.00028826317,0.00035544205,0.000039269282,0.00003942035,0.0012152242],"genre_scores_gemma":[0.99962735,0.000004000954,0.000033516153,0.0001688979,0.000076161166,0.000014685838,0.000018547245,0.000005209664,0.0000516402],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9991426,0.000057812755,0.0004006767,0.00008147333,0.00020650834,0.00011096551],"domain_scores_gemma":[0.9994362,0.000006351167,0.00023621491,0.00021965036,0.00006310008,0.000038468082],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001227152,0.00009625733,0.00015374049,0.0001234025,0.00008363491,0.000020740694,0.00003970269,0.00009001763,0.000013509847],"category_scores_gemma":[0.000017993165,0.00006116723,0.000037329497,0.00015710921,0.00005148343,0.00047130277,0.000027948554,0.00007009256,0.00003255413],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009307232,0.00001735816,0.95553255,0.00039381464,0.00005099033,0.0000037282466,0.03948248,0.000010116357,0.00093806675,0.00016458554,0.00014846213,0.002327097],"study_design_scores_gemma":[0.0021358607,0.00012521152,0.84231615,0.00047056732,0.000029652352,0.0000331611,0.0008242293,0.0009915205,0.15290625,0.000007806319,0.00008209315,0.00007749567],"about_ca_topic_score_codex":0.00019293644,"about_ca_topic_score_gemma":0.000002462696,"teacher_disagreement_score":0.15196818,"about_ca_system_score_codex":0.000050555514,"about_ca_system_score_gemma":0.00003755016,"threshold_uncertainty_score":0.24943271},"labels":[],"label_agreement":null},{"id":"W6958683978","doi":"10.6084/m9.figshare.29604851","title":"Additional file 3 of Targeting autophagy and plasminogen activator inhibitor-1 increases survival and remodels the tumor microenvironment in glioblastoma","year":2025,"lang":"en","type":"article","venue":"Figshare","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Glioblastoma; Autophagy; Tumor microenvironment; Plasminogen activator; Activator (genetics); Tumor cells","score_opus":0.009867472126617038,"score_gpt":0.2297813828158426,"score_spread":0.21991391068922556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6958683978","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.19033569,0.0005711049,6.295905e-8,0.000051040606,0.000007873928,0.00020189495,0.80837274,0.000013476767,0.00044610104],"genre_scores_gemma":[0.67689234,0.000016424025,0.00014806021,0.00057612115,0.0001399971,0.0005794967,0.3210323,0.000022491662,0.0005927714],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993428,0.00003998128,0.00017092223,0.0001853913,0.0001291158,0.00013176216],"domain_scores_gemma":[0.9988426,0.00088287255,0.00007332249,0.00012129407,0.000021588367,0.00005833498],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000026691458,0.000112031456,0.00018114306,0.0000637674,0.000059463993,0.000010077269,0.00005383516,0.00004482452,0.77729607],"category_scores_gemma":[0.0007483634,0.00008578289,0.000035245932,0.00009653824,0.000032879117,0.000056861867,0.00009868887,0.0001084652,0.000033094664],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016159649,0.00009297355,0.00006347138,0.00014642028,0.000039169205,0.00003654846,0.000038487382,0.000001590967,0.0012647009,0.000005820289,0.9970939,0.0010553064],"study_design_scores_gemma":[0.0029071486,0.0003209166,0.25024402,0.010897376,0.0000562684,0.000064706124,0.00057383167,0.001123742,0.09170675,0.00023670094,0.6415283,0.00034020536],"about_ca_topic_score_codex":0.00000793968,"about_ca_topic_score_gemma":0.0000037512882,"teacher_disagreement_score":0.777263,"about_ca_system_score_codex":0.00003221848,"about_ca_system_score_gemma":0.00010473757,"threshold_uncertainty_score":0.34981248},"labels":[],"label_agreement":null},{"id":"W6976300402","doi":"10.60692/33gyv-y7n72","title":"Autophagy in major human diseases","year":2021,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Grossman; Biological sciences; Research center; Section (typography); Cancer; Medical school; Publishing","score_opus":0.024463391884650295,"score_gpt":0.24994327423306206,"score_spread":0.22547988234841176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6976300402","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914212,0.000046025383,0.00039203843,0.00006379266,0.00017250016,0.000248247,0.00006445549,0.00018215504,0.0074095377],"genre_scores_gemma":[0.99837536,2.2819825e-7,0.000050659582,0.0005878957,0.000093976916,0.000053981872,0.00010743334,0.000009531437,0.0007209466],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9989776,0.00003981687,0.00044185805,0.0001191374,0.00023353772,0.00018803363],"domain_scores_gemma":[0.9993134,0.0000034325312,0.000102140686,0.00033795965,0.000109929955,0.00013312596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007553116,0.00012476777,0.00024775436,0.00017835076,0.00006925585,0.000058535512,0.0000572305,0.0000729302,0.00026261483],"category_scores_gemma":[0.000013531008,0.00010589568,0.00009522829,0.00023224126,0.000018933213,0.00030436428,0.000027960237,0.00007528358,0.0006664854],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025960413,0.000041155887,0.9552354,0.0016829396,0.00019618009,0.0006962168,0.037494082,0.000028514545,0.00009363794,0.0027719194,0.00050612935,0.0009941758],"study_design_scores_gemma":[0.004137195,0.00004643704,0.9810795,0.0003425697,0.00007424542,0.0001311326,0.0065158466,0.00036232534,0.0065090456,0.000008802806,0.0006236214,0.00016926871],"about_ca_topic_score_codex":0.0000042363067,"about_ca_topic_score_gemma":1.831285e-7,"teacher_disagreement_score":0.030978234,"about_ca_system_score_codex":0.00010594051,"about_ca_system_score_gemma":0.00009506382,"threshold_uncertainty_score":0.85665435},"labels":[],"label_agreement":null},{"id":"W6976503868","doi":"10.60692/1hgp3-vx464","title":"Autophagy in protists and their hosts: When, how and why?","year":2023,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Autophagy; Protist; Intracellular parasite; Protozoa; Model organism; Mechanism (biology); Autophagosome; Organism","score_opus":0.02686929115108009,"score_gpt":0.22170326668140242,"score_spread":0.19483397553032233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6976503868","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99736196,0.000040209037,0.00041257803,0.00045056042,0.000094855226,0.00067285437,0.00004051534,0.00023794743,0.00068853906],"genre_scores_gemma":[0.9990743,0.00000259715,0.000034302797,0.00042305505,0.000044886398,0.000105873194,0.000025007688,0.00000921811,0.0002807739],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99931175,0.000030222089,0.00024033379,0.00011385955,0.00012751986,0.00017633261],"domain_scores_gemma":[0.9995735,0.000006945426,0.00008745567,0.00018317958,0.00004792514,0.000100943995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020536232,0.00013106324,0.0002192306,0.0002765946,0.00005361998,0.00009041548,0.00003854674,0.000080577534,0.000010363702],"category_scores_gemma":[0.0000139515405,0.00009266256,0.000026840495,0.00018228668,0.000033207132,0.00038335967,0.000035001744,0.00007132121,0.00009828222],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039833266,0.000008756095,0.6331803,0.0035969072,0.00017099665,0.00011886676,0.349239,0.0000049478285,0.00005580769,0.0008351356,0.0017041941,0.010686739],"study_design_scores_gemma":[0.0040063323,0.00013069638,0.9611851,0.0006316097,0.000022096312,0.00019703929,0.024894355,0.004930029,0.001913337,0.00002594037,0.0018470366,0.00021641512],"about_ca_topic_score_codex":0.000005462386,"about_ca_topic_score_gemma":2.4276628e-7,"teacher_disagreement_score":0.3280048,"about_ca_system_score_codex":0.000040297607,"about_ca_system_score_gemma":0.00002473256,"threshold_uncertainty_score":0.37786692},"labels":[],"label_agreement":null},{"id":"W6977494626","doi":"10.60692/4q53j-6zd55","title":"Blockade of Uttroside B-Induced Autophagic Pro-Survival Signals Augments Its Chemotherapeutic Efficacy Against Hepatocellular Carcinoma","year":2022,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Autophagy; Bafilomycin; Apoptosis; Hepatocellular carcinoma; Blockade; Chloroquine; Cytotoxicity; Cancer cell","score_opus":0.05664768846057101,"score_gpt":0.251053576676268,"score_spread":0.194405888215697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6977494626","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957919,0.00005488576,0.00025748968,0.00005460792,0.0004016403,0.0014971759,0.00012248197,0.00021052266,0.0016092914],"genre_scores_gemma":[0.9987921,3.5870931e-7,0.000027770673,0.0004531815,0.00009497088,0.00022086696,0.000087765206,0.00003315457,0.0002898162],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974615,0.00015301099,0.00094172754,0.00022385544,0.00086505956,0.00035482977],"domain_scores_gemma":[0.9985434,0.000012518414,0.0005583931,0.0005277022,0.00017751336,0.00018051261],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042195644,0.00028388406,0.00055124005,0.00032140533,0.0002296311,0.000038031863,0.00023313884,0.00009596883,0.00024320043],"category_scores_gemma":[0.000011633833,0.00025352326,0.00023638693,0.00038804696,0.00002574506,0.00023411211,0.000094792515,0.00021047403,0.00020389816],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0045065912,0.00042502637,0.7319031,0.0065040747,0.0025228339,0.00029656565,0.19593741,0.0014758819,0.052077614,0.00042922096,0.000146616,0.0037750672],"study_design_scores_gemma":[0.020823138,0.0011246529,0.27999914,0.00045318302,0.000545128,0.00019418937,0.015330687,0.042107217,0.6380035,0.0000034635825,0.00056529464,0.0008503716],"about_ca_topic_score_codex":0.0000051644793,"about_ca_topic_score_gemma":8.966176e-9,"teacher_disagreement_score":0.58592594,"about_ca_system_score_codex":0.00026168316,"about_ca_system_score_gemma":0.00019254454,"threshold_uncertainty_score":0.9999917},"labels":[],"label_agreement":null},{"id":"W69881358","doi":"10.1016/j.jmb.2019.12.035","title":"Autophagy Induction as a Therapeutic Strategy for Neurodegenerative Diseases","year":2019,"lang":"en","type":"review","venue":"Journal of Molecular Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":240,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Cambridge Centre for Parkinson-Plus; Ontario Ministry of Research and Innovation; National Institute for Health and Care Research; Tau Consortium; National Institutes of Health; Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii; Medical Research Council; Fondation Roger de Spoelberch; Alzheimer's Society; Cambridge Trust; UK Dementia Research Institute; Alzheimer’s Research UK; NIHR Cambridge Biomedical Research Centre; Raymond and Beverly Sackler Foundation","keywords":"Autophagy; Biology; Computational biology; Neuroscience; Cell biology; Genetics; Apoptosis","score_opus":0.08706765566896756,"score_gpt":0.43503596780787235,"score_spread":0.3479683121389048,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W69881358","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009919859,0.99492514,0.0021017438,0.000074568845,0.0008002979,0.0009483551,0.000057690268,0.000012874309,0.00008733387],"genre_scores_gemma":[0.0017839596,0.9961981,0.00014532365,0.0006410118,0.0007281344,0.000044280783,0.0001399526,0.000068614914,0.00025060703],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99822277,0.0003438087,0.0007441208,0.00028799623,0.00015014525,0.00025116932],"domain_scores_gemma":[0.99818295,0.00012944294,0.0009552518,0.000299065,0.00025940852,0.00017387961],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015775183,0.00036042047,0.0018975624,0.00030306957,0.00003841213,0.000017368002,0.00020459846,0.000422446,0.000093579394],"category_scores_gemma":[0.0000974213,0.0002366343,0.001358207,0.00015070738,0.00008179426,0.0000418968,0.000022751265,0.00044399465,0.00002689919],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029150714,0.00026586372,0.0000020629557,0.0029964559,0.0023472167,0.00027127843,0.000014142793,0.0000068365944,0.0017567324,0.0028352817,0.00020899854,0.9890036],"study_design_scores_gemma":[0.0019423052,0.0058984472,0.000024870515,0.0022757181,0.008050364,0.0021390626,0.000016294262,0.000007887219,0.001215824,0.0044244574,0.97366536,0.0003394056],"about_ca_topic_score_codex":0.000001244639,"about_ca_topic_score_gemma":6.8866925e-8,"teacher_disagreement_score":0.9886642,"about_ca_system_score_codex":0.00008736712,"about_ca_system_score_gemma":0.0014281002,"threshold_uncertainty_score":0.96496665},"labels":[],"label_agreement":null},{"id":"W6995355444","doi":"","title":"Nest of Stone","year":2016,"lang":"en","type":"other","venue":"University of the Arts London Research Online (University of the Arts London)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Movie theater; Jury; Atmosphere (unit); Nest (protein structural motif)","score_opus":0.03379101343650468,"score_gpt":0.30302888356630026,"score_spread":0.26923787012979555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6995355444","genre_codex":"empirical","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6323376,0.0033365635,0.00031063773,0.038346227,0.0008990368,0.00411141,0.0027056723,0.0002452013,0.3177076],"genre_scores_gemma":[0.089215785,0.0025500825,0.000565508,0.00010418145,0.00015205539,8.405594e-8,0.000046643625,0.00013078483,0.90723485],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969999,0.0004106433,0.00021224639,0.0004822019,0.0013784089,0.0005166026],"domain_scores_gemma":[0.9963394,0.00022786499,0.0006571128,0.0019916035,0.0005220948,0.00026195263],"candidate_categories":["sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00053632405,0.0003075702,0.00083788444,0.00068825716,0.0004127942,0.0000051348325,0.0021470136,0.00033512953,0.0063878396],"category_scores_gemma":[0.00010687835,0.00023446573,0.0008051253,0.0006233476,0.0029547256,0.00013226131,0.0014673055,0.0006986351,0.00013645868],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00380357,0.0027469627,0.0054301624,0.0012422646,0.0021273796,0.0003523967,0.0019059796,0.000020036043,0.011252575,0.004359996,0.95830667,0.008451983],"study_design_scores_gemma":[0.0063408487,0.00041357975,0.019964116,0.0027047482,0.0006140805,0.000025029654,0.0026745591,0.00006777902,0.0024886106,0.00055516907,0.96379066,0.000360841],"about_ca_topic_score_codex":0.0035543898,"about_ca_topic_score_gemma":0.002470674,"teacher_disagreement_score":0.58952725,"about_ca_system_score_codex":0.0001775976,"about_ca_system_score_gemma":0.0006589534,"threshold_uncertainty_score":0.99975866},"labels":[],"label_agreement":null},{"id":"W6995678240","doi":"","title":"Phytogeography, genetic variation and antioxidant phytochemistry of Â«SorbusÂ» spp. in the Eeyou Istchee, James Bay, region of Quebec","year":2010,"lang":"en","type":"other","venue":"Library and Archives Canada (Government of Canada)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Genetic variation; Antioxidant; Genetic analysis; Bark (sound); Genetic variability; Gene; Gene expression","score_opus":0.0026607724495015207,"score_gpt":0.15850426983367882,"score_spread":0.1558434973841773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6995678240","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.58420557,0.0094358595,0.000055612974,0.0015738732,0.00017693946,0.0007671282,0.00054807664,0.000013758247,0.4032232],"genre_scores_gemma":[0.9746956,0.0021458643,0.00038079548,0.0004607241,0.00010821018,0.000009951594,0.000020340762,0.00006174316,0.022116736],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99844843,0.000043863685,0.0002937985,0.00020893755,0.00085340923,0.00015157094],"domain_scores_gemma":[0.99915874,0.0000906384,0.00035051364,0.0003021745,9.542646e-7,0.00009695607],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000119586275,0.00019631702,0.00039205435,0.000049068978,0.00002472659,0.0000050594767,0.00014562912,0.00008347767,0.00006737844],"category_scores_gemma":[0.0000031964828,0.0001547057,0.000047770904,0.000088860514,0.00017670906,0.000043578435,0.000038812097,0.0001777108,6.9728207e-10],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0043152287,0.0011170249,0.52649,0.014479775,0.0022383113,0.0013028232,0.0016154671,0.000015024829,0.32364562,0.020069152,0.05333395,0.05137766],"study_design_scores_gemma":[0.0013403257,0.00012755577,0.9093704,0.0012365611,0.0001729295,0.00003115272,0.0012230746,0.00010584801,0.058239873,0.00074142584,0.027125144,0.00028566908],"about_ca_topic_score_codex":0.03203231,"about_ca_topic_score_gemma":0.06019065,"teacher_disagreement_score":0.39049008,"about_ca_system_score_codex":0.000002878813,"about_ca_system_score_gemma":0.0009398833,"threshold_uncertainty_score":0.97441345},"labels":[],"label_agreement":null},{"id":"W6995691405","doi":"","title":"480.phpماذا تنتظرون ؟","year":2022,"lang":"ar","type":"other","venue":"Bulletin of Miscellaneous Information (Royal Gardens Kew)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Islam; Brother; State (computer science); Supporter","score_opus":0.005976500595268828,"score_gpt":0.1989795112196625,"score_spread":0.19300301062439368,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6995691405","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011580124,0.0037172323,1.0753816e-7,0.00039024276,0.001064871,0.001180089,0.0004805135,0.00022891191,0.99178004],"genre_scores_gemma":[0.006053466,0.0022083824,0.0002425331,0.0022622724,0.0007110222,0.000071803195,0.00091383257,0.00024053486,0.98729616],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99593574,0.00023822834,0.0014240138,0.0004713713,0.0012085581,0.0007220927],"domain_scores_gemma":[0.9969161,0.00018881205,0.0011488799,0.0010635138,0.00024064448,0.0004420102],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00047695616,0.00077983324,0.001109985,0.00018688089,0.000265408,0.00006226387,0.00065756915,0.0006390989,0.98396343],"category_scores_gemma":[0.00021131056,0.00078518846,0.00062591425,0.00002200379,0.00031608113,2.496294e-7,0.00025780097,0.0009151405,0.1911218],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00072037545,0.00028161315,0.000021840864,0.0012328165,0.00062386045,0.00028624927,0.00068253616,0.00021433218,0.0000013280277,0.00012758558,0.99231946,0.0034879695],"study_design_scores_gemma":[0.0026631511,0.0010115965,0.00007414262,0.00042545891,0.00051102496,0.00022681654,0.0008111967,0.000034853012,0.00002972606,0.000032002874,0.9934791,0.00070097385],"about_ca_topic_score_codex":0.0020516787,"about_ca_topic_score_gemma":0.00014220426,"teacher_disagreement_score":0.7928416,"about_ca_system_score_codex":0.00025356788,"about_ca_system_score_gemma":0.00020381759,"threshold_uncertainty_score":0.9994599},"labels":[],"label_agreement":null},{"id":"W6996451662","doi":"","title":"Roles of autophagy &amp; mitophagy in the regulation of skeletal muscle function","year":2021,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Genome Canada; Canadian Institutes of Health Research; McGill University Health Centre; Génome Québec; McGill University","keywords":"Autophagy; Mitophagy; Skeletal muscle; Function (biology); Myocyte","score_opus":0.01520073568744058,"score_gpt":0.26323156644352663,"score_spread":0.24803083075608606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6996451662","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9770733,0.0029537296,4.944316e-7,0.000017357277,0.0007008458,0.0007730696,0.00027375744,0.00006165173,0.018145783],"genre_scores_gemma":[0.99200875,0.00040229518,0.00018079743,0.00018917401,0.00009812293,0.00010032422,0.0030377726,0.000107329004,0.0038754155],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99616426,0.00047493348,0.0012005906,0.00068388146,0.0010798861,0.00039643864],"domain_scores_gemma":[0.9972324,0.00024073162,0.0008398194,0.0010228277,0.0005313914,0.00013282358],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007827847,0.0005143932,0.0009805948,0.00048135032,0.0002207451,0.000018656645,0.00034916075,0.0007266135,0.00077037397],"category_scores_gemma":[0.000424326,0.00044550817,0.00061913126,0.00087881536,0.00008711695,0.00029531287,0.00004105764,0.00093546475,0.000039721228],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012648631,0.0016893934,0.00019826741,0.0018129923,0.0006661921,0.00008341975,0.00015195683,0.000066627195,0.7387733,0.03448613,0.000017617569,0.22078928],"study_design_scores_gemma":[0.004335937,0.0006835496,0.5317764,0.0019815348,0.0011613978,0.000051922754,0.0018188376,0.00003565334,0.40748143,0.020764858,0.029086301,0.00082217494],"about_ca_topic_score_codex":0.00018021603,"about_ca_topic_score_gemma":0.0010314302,"teacher_disagreement_score":0.5315781,"about_ca_system_score_codex":0.0002028988,"about_ca_system_score_gemma":0.00014818707,"threshold_uncertainty_score":0.99979967},"labels":[],"label_agreement":null},{"id":"W7008550309","doi":"","title":"Characterizing the Role of the PÎ˛ Peptide: A Potential Mitochondria to Nuclear Signal in Mitochondrial Quality Control","year":2016,"lang":"en","type":"dissertation","venue":"TSpace (University of Toronto)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Mitochondrion; Mitophagy; Proteolysis; Parkin; PINK1; Peptide; Cytosol; Proteasome","score_opus":0.006835150456547206,"score_gpt":0.2501299337800406,"score_spread":0.2432947833234934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7008550309","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9821253,0.00051410065,0.000029883624,0.0014209617,0.00064941903,0.0010796643,0.000106122934,0.00002331952,0.014051235],"genre_scores_gemma":[0.9926246,0.00008540447,0.00009242777,0.00012721233,0.00025200736,0.0000017357877,0.00003501085,0.000027523893,0.0067540724],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985397,0.00020473244,0.00023254404,0.00030603432,0.00047249673,0.00024449878],"domain_scores_gemma":[0.9986418,0.00007506179,0.00046354573,0.000539863,0.00016234441,0.000117425785],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014147343,0.00022298825,0.0005862356,0.00005233728,0.00015877408,0.000008571093,0.0004944165,0.0002580881,0.0069084084],"category_scores_gemma":[0.000042702643,0.00016163742,0.0004451352,0.00007360129,0.00010666304,0.00015079694,0.00005703926,0.00022995925,0.000022332184],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01124465,0.00027956514,0.00061001605,0.000146203,0.00048765432,0.000020979076,0.027338697,0.00000208071,0.9421614,0.0005067565,0.00043028963,0.016771698],"study_design_scores_gemma":[0.0060742144,0.0003350246,0.94337004,0.0008906533,0.0005830144,0.0000036041893,0.03853922,0.000058403388,0.006184494,0.00009050836,0.0035435867,0.00032721425],"about_ca_topic_score_codex":0.028315628,"about_ca_topic_score_gemma":0.012279905,"teacher_disagreement_score":0.94276005,"about_ca_system_score_codex":0.00021734663,"about_ca_system_score_gemma":0.00023289738,"threshold_uncertainty_score":0.9939994},"labels":[],"label_agreement":null},{"id":"W7008983950","doi":"","title":"Deciphering the role of autophagy-mediated focal adhesion turnover in cancer cells and therapeutic implications","year":2017,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fondation du cancer du sein du Québec","keywords":"Cancer; Cell adhesion; Adhesion; Cancer cell; Focal adhesion; Extracellular matrix","score_opus":0.01799832555307439,"score_gpt":0.28917622295385575,"score_spread":0.27117789740078135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7008983950","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97892123,0.008340328,4.6555687e-8,0.000029750472,0.00036654127,0.0009687563,0.0005791859,0.00006866736,0.010725512],"genre_scores_gemma":[0.99459606,0.002791897,0.000030403806,0.00023917,0.000054735814,0.00029776365,0.0002641568,0.00012621624,0.001599579],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997628,0.00014395466,0.00067214883,0.0006451691,0.000457557,0.0004531837],"domain_scores_gemma":[0.9977291,0.00026147117,0.00060118845,0.00095258787,0.00022718174,0.00022846786],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003725764,0.0004951615,0.0007279308,0.00021547424,0.0005656128,0.000039328705,0.00045088812,0.00058595126,0.00025943996],"category_scores_gemma":[0.000129123,0.00038757673,0.00024819272,0.00025586283,0.00012122421,0.00020182584,0.000046844198,0.0009971773,0.000029341945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058354833,0.00032677499,0.0010771147,0.00024940027,0.00035054528,0.000022391107,0.0000707365,0.000011254521,0.73392445,0.0038287546,0.0000014809575,0.25955352],"study_design_scores_gemma":[0.0023927332,0.00021619016,0.2509697,0.0011053671,0.0006077269,0.00001704917,0.0003404765,0.00011073347,0.7099082,0.011858696,0.021880923,0.00059222814],"about_ca_topic_score_codex":0.00063966244,"about_ca_topic_score_gemma":0.0012895563,"teacher_disagreement_score":0.2589613,"about_ca_system_score_codex":0.00028910008,"about_ca_system_score_gemma":0.00014875,"threshold_uncertainty_score":0.9998576},"labels":[],"label_agreement":null},{"id":"W7031487716","doi":"","title":"Cincinnati, Ohio","year":2009,"lang":"en","type":"other","venue":"OhioLink ETD Center (Ohio Library and Information Network)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Fountain; Yard; Alley; Gallon (US); Quarter (Canadian coin); Electric light; George (robot); Phoenix","score_opus":0.007231384565035599,"score_gpt":0.21684544719034207,"score_spread":0.20961406262530646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7031487716","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000040755684,0.004158181,0.00018165493,0.00093423825,0.00057260046,0.0006898457,0.00013665888,0.0006577568,0.99262834],"genre_scores_gemma":[0.012885521,0.048795562,0.00252807,0.08290885,0.008415409,0.00008100777,0.012047344,0.00064069283,0.8316975],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99834883,0.00005355267,0.00058446324,0.00025694448,0.00027880774,0.00047742823],"domain_scores_gemma":[0.99874055,0.000025093672,0.00038772487,0.0004772525,0.000017560538,0.0003518284],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007237198,0.00046396628,0.00058302394,0.00033244397,0.00010014846,0.00012913348,0.00018298606,0.0005340064,0.0084975865],"category_scores_gemma":[0.000005206859,0.00039658032,0.00018830305,0.00028648233,0.000073767835,0.002437191,0.000087515466,0.0004615589,0.00032105154],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020048206,0.00007646594,0.00009507534,0.00023213672,0.00017762523,0.000019144532,0.00006912473,0.000006516883,7.08602e-7,0.14637768,0.8250578,0.02768723],"study_design_scores_gemma":[0.0020532345,0.00017379534,0.0019062968,0.0009958707,0.000082227765,0.000051934338,0.0000027754725,0.000278926,0.000027797774,0.0004580691,0.99359673,0.0003723205],"about_ca_topic_score_codex":7.176053e-8,"about_ca_topic_score_gemma":2.8967085e-7,"teacher_disagreement_score":0.16853894,"about_ca_system_score_codex":0.000012974272,"about_ca_system_score_gemma":0.00011241759,"threshold_uncertainty_score":0.9998486},"labels":[],"label_agreement":null},{"id":"W7037780579","doi":"","title":"Exploring the Significance of Autophagy in Host Defense in an Enteric Parasitic Infection","year":2024,"lang":"en","type":"dissertation","venue":"MacSphere (McMaster University)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University Medical Centre","funders":"","keywords":"Autophagy; Immune system; ATG16L1; Host (biology); In vitro; Feces; Gut flora; Intestinal mucosa","score_opus":0.033517721819643374,"score_gpt":0.26029856192736606,"score_spread":0.22678084010772268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7037780579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.955226,0.00035240882,0.0000103711245,0.000021851352,0.0004295142,0.00051321153,0.000009097866,0.000048292182,0.043389246],"genre_scores_gemma":[0.9430508,0.0003207202,0.000014131295,0.000039060633,0.000061027247,0.000013727117,0.00009705724,0.000038293427,0.056365192],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.998837,0.00012343921,0.00025634427,0.00036576914,0.00019309834,0.00022433011],"domain_scores_gemma":[0.99944633,0.000045507113,0.00011418758,0.00027144753,0.000048959533,0.00007358124],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008729207,0.00023706093,0.000365504,0.000428638,0.000035528632,0.000020159996,0.0001487012,0.00013489257,0.004091752],"category_scores_gemma":[0.000009405575,0.00021539073,0.0001358012,0.0009034705,0.000046413523,0.00025452726,0.00001739302,0.00042549864,0.000030923533],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012017708,0.0032331252,0.15213144,0.008566416,0.0011300466,0.010256468,0.05328054,0.00089681946,0.059593074,0.005125543,0.00013232697,0.6936365],"study_design_scores_gemma":[0.0029190206,0.000707923,0.95238596,0.0026703195,0.00054644747,0.000015435671,0.012685678,0.0005034473,0.014888449,0.00021515299,0.011919147,0.0005430005],"about_ca_topic_score_codex":0.0007249731,"about_ca_topic_score_gemma":0.0034479732,"teacher_disagreement_score":0.8002545,"about_ca_system_score_codex":0.00023320931,"about_ca_system_score_gemma":0.00016024378,"threshold_uncertainty_score":0.99681866},"labels":[],"label_agreement":null},{"id":"W7066333412","doi":"","title":"Investigating the effects of acute oxidative stress on the expression, localization and activity of cell death regulatory protein BNIP3","year":2017,"lang":"en","type":"dissertation","venue":"Mspace (University of Manitoba)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Programmed cell death; Oxidative stress; Autophagy; Gene knockdown; Mitochondrion; Cell; Reactive oxygen species; Oxidative phosphorylation; Apoptosis","score_opus":0.01142094112595967,"score_gpt":0.22928287740949543,"score_spread":0.21786193628353576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7066333412","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975096,0.00015923218,0.00010269166,0.00013376419,0.000056128614,0.0009439244,0.000031911764,0.00001127061,0.0010514503],"genre_scores_gemma":[0.9986203,0.00012963716,0.00007559459,0.000015020853,0.00002155823,0.0000018223806,0.000065878805,0.000015805077,0.0010544357],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991025,0.00017620991,0.000084441344,0.00019983697,0.000338352,0.00009869646],"domain_scores_gemma":[0.9983158,0.00017345812,0.000801091,0.00048667847,0.00016930775,0.00005363733],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013793072,0.00016592785,0.00033524388,0.00007704298,0.00027769647,0.0000066138487,0.00023263774,0.00017263985,0.000005199928],"category_scores_gemma":[0.000084771396,0.00012185844,0.000097708806,0.00006796336,0.00026082055,0.00009629091,0.000042749078,0.00022156368,8.4097087e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010971784,0.00039029977,0.013279117,0.004107243,0.00065829663,0.000029049701,0.0051876446,0.000013327394,0.97250843,0.0007092488,0.0006399361,0.0013802283],"study_design_scores_gemma":[0.0006562645,0.00025568323,0.24741845,0.0023606296,0.00040641215,3.1816643e-7,0.005103528,0.00010892556,0.7434075,0.00018140205,0.000018683304,0.00008218855],"about_ca_topic_score_codex":0.00039144617,"about_ca_topic_score_gemma":0.0013386474,"teacher_disagreement_score":0.23413934,"about_ca_system_score_codex":0.00003273986,"about_ca_system_score_gemma":0.00012256799,"threshold_uncertainty_score":0.49692428},"labels":[],"label_agreement":null},{"id":"W7084756029","doi":"10.48495/hd76sb148","title":"Note written by Henry Labouchere [1889/1890]. IE TCD MS 9384/1235","year":2025,"lang":"en","type":"other","venue":"Digital Collections (East Carolina University)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"MEDLINE; Period (music); Key (lock)","score_opus":0.005352131429987344,"score_gpt":0.21134156716544222,"score_spread":0.2059894357354549,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7084756029","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00024323656,0.0016409296,0.0010734848,0.00023978324,0.0004919217,0.00087653287,0.0030591148,0.0006628,0.9917122],"genre_scores_gemma":[0.009976268,0.00046893806,0.00006491997,0.00024296684,0.0005103588,0.000009722621,0.00063425925,0.00024697318,0.9878456],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99820566,0.00004777944,0.00022543452,0.000697641,0.00035706817,0.00046639788],"domain_scores_gemma":[0.9985573,0.00004817431,0.00016820063,0.0006438802,0.0002121427,0.00037028219],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000030232117,0.0005216365,0.00070416706,0.0015622049,0.00038071765,0.00012101093,0.00032775287,0.000622953,0.0024658735],"category_scores_gemma":[0.00003365725,0.00059231906,0.0004760428,0.0026639462,0.00022096194,0.00019442028,0.00014184626,0.0005391557,0.00027401044],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052187365,0.0006743694,0.0007237032,0.00024931107,0.0011692757,0.00087826885,0.000065784916,0.0000032608682,0.00002804069,0.00095792225,0.992061,0.0026671586],"study_design_scores_gemma":[0.002543953,0.00020031106,0.00009851497,0.00033515037,0.0005163464,0.000060124483,0.00021360631,0.000012804865,0.000069798814,0.00012411286,0.99534595,0.00047935266],"about_ca_topic_score_codex":0.00035980972,"about_ca_topic_score_gemma":0.00010666387,"teacher_disagreement_score":0.0097330315,"about_ca_system_score_codex":0.00054477743,"about_ca_system_score_gemma":0.0011383817,"threshold_uncertainty_score":0.9996528},"labels":[],"label_agreement":null},{"id":"W7093838303","doi":"","title":"The Smart Outdoor Power Equipment Market to Hit $11.56 Billion by 2029 – Arizton – US and Canada Report","year":2025,"lang":"en","type":"other","venue":"","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Power (physics); Electronic equipment; Electricity; Electric power industry","score_opus":0.0034904669281300205,"score_gpt":0.23597029970201097,"score_spread":0.23247983277388096,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7093838303","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011740274,0.0041886037,0.0000620064,0.007471762,0.001244274,0.001069,0.00017258554,0.00009608512,0.9845216],"genre_scores_gemma":[0.0027320236,0.000723143,0.00005736961,0.006802587,0.00016012791,0.00006117764,0.000101021564,0.00013741934,0.98922515],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99840945,0.000037338803,0.00031427955,0.00046203643,0.00044947892,0.00032742607],"domain_scores_gemma":[0.9987775,0.000061169325,0.00013054615,0.00069810933,0.000046467365,0.00028621286],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020445527,0.00030924098,0.00040182503,0.00009529333,0.000084346764,0.000033000757,0.00013150828,0.00018754305,0.015317768],"category_scores_gemma":[0.000059641618,0.00018813398,0.000092622744,0.00010389562,0.00004431564,0.0000103806115,0.000088067725,0.0001506956,0.000020140995],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009428082,0.000041333995,0.0017555925,0.00004591605,0.00037174186,0.0004694429,0.0000069749863,1.9557493e-8,0.000028054877,0.000081262755,0.99494857,0.0021568018],"study_design_scores_gemma":[0.0005066597,0.00007244301,0.0033887231,0.00020860863,0.00013995494,0.000029184223,0.000044174492,0.0000019290933,0.0001681909,0.000023698261,0.99520653,0.00020989458],"about_ca_topic_score_codex":0.4868837,"about_ca_topic_score_gemma":0.4380524,"teacher_disagreement_score":0.04883129,"about_ca_system_score_codex":0.00018990907,"about_ca_system_score_gemma":0.0010833995,"threshold_uncertainty_score":0.98558235},"labels":[],"label_agreement":null},{"id":"W7106244845","doi":"10.5281/zenodo.17657471","title":"Autophagy maintains stemness by preventing senescence.","year":2016,"lang":"","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Autophagy; Senescence; Satellite; Regeneration (biology); Stem cell; Cellular senescence; Function (biology); Sarcopenia","score_opus":0.024087371508776764,"score_gpt":0.2602948415532852,"score_spread":0.23620747004450843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7106244845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5634546,0.011266836,0.07290066,0.012507898,0.0027319214,0.007128357,0.005242347,0.0063336217,0.31843373],"genre_scores_gemma":[0.970554,0.0016748367,0.00007911488,0.00043470482,0.00069324125,1.2806946e-7,0.0008952142,0.003043811,0.022624964],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99521685,0.000948031,0.00073772256,0.001030002,0.0009068897,0.0011604911],"domain_scores_gemma":[0.9968453,0.00008720181,0.0003515414,0.0011050412,0.0008383109,0.00077260734],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0013398994,0.00044376735,0.00047921398,0.0003077539,0.0031957862,0.00066752883,0.0013845952,0.000228357,0.11734795],"category_scores_gemma":[0.00084118225,0.00037308095,0.00021501555,0.0007767389,0.00054911117,0.0005181888,0.0013292242,0.00041076294,0.028932652],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00056585256,0.0010567484,0.000027748949,0.00041664456,0.00047656387,0.00020023446,0.0013545528,0.0000020509995,0.15534315,0.004162672,0.23344396,0.60294986],"study_design_scores_gemma":[0.003784739,0.0007920809,0.0013014828,0.0008095364,0.00016148076,0.00024170474,0.00064498145,0.00021819999,0.027761756,0.00033088558,0.9634171,0.00053606165],"about_ca_topic_score_codex":0.000013448916,"about_ca_topic_score_gemma":8.843499e-8,"teacher_disagreement_score":0.72997314,"about_ca_system_score_codex":0.00053951936,"about_ca_system_score_gemma":0.000028343478,"threshold_uncertainty_score":0.9998721},"labels":[],"label_agreement":null},{"id":"W7106333003","doi":"10.5281/zenodo.17657472","title":"Autophagy maintains stemness by preventing senescence.","year":2016,"lang":"","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Autophagy; Senescence; Satellite; Regeneration (biology); Stem cell; Cellular senescence; Function (biology); Sarcopenia","score_opus":0.024087371508776764,"score_gpt":0.2602948415532852,"score_spread":0.23620747004450843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7106333003","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5634546,0.011266836,0.07290066,0.012507898,0.0027319214,0.007128357,0.005242347,0.0063336217,0.31843373],"genre_scores_gemma":[0.970554,0.0016748367,0.00007911488,0.00043470482,0.00069324125,1.2806946e-7,0.0008952142,0.003043811,0.022624964],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99521685,0.000948031,0.00073772256,0.001030002,0.0009068897,0.0011604911],"domain_scores_gemma":[0.9968453,0.00008720181,0.0003515414,0.0011050412,0.0008383109,0.00077260734],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0013398994,0.00044376735,0.00047921398,0.0003077539,0.0031957862,0.00066752883,0.0013845952,0.000228357,0.11734795],"category_scores_gemma":[0.00084118225,0.00037308095,0.00021501555,0.0007767389,0.00054911117,0.0005181888,0.0013292242,0.00041076294,0.028932652],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00056585256,0.0010567484,0.000027748949,0.00041664456,0.00047656387,0.00020023446,0.0013545528,0.0000020509995,0.15534315,0.004162672,0.23344396,0.60294986],"study_design_scores_gemma":[0.003784739,0.0007920809,0.0013014828,0.0008095364,0.00016148076,0.00024170474,0.00064498145,0.00021819999,0.027761756,0.00033088558,0.9634171,0.00053606165],"about_ca_topic_score_codex":0.000013448916,"about_ca_topic_score_gemma":8.843499e-8,"teacher_disagreement_score":0.72997314,"about_ca_system_score_codex":0.00053951936,"about_ca_system_score_gemma":0.000028343478,"threshold_uncertainty_score":0.9998721},"labels":[],"label_agreement":null},{"id":"W7111891364","doi":"","title":"PEROXISOOMDYSFUNCTIE EN AUTOFAGIE: DE KLOOF OVERBRUGGEN","year":2025,"lang":"en","type":"article","venue":"Lirias","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Illinois at Urbana-Champaign; University of Toronto; National Institutes of Health; Universiteit van Amsterdam; Vlaamse regering; Servier; European Commission; China Scholarship Council; KU Leuven; Florida State University","keywords":"Peroxisome; Autophagy; Organelle; Intracellular; ATG8; Mitophagy","score_opus":0.0031941110646028937,"score_gpt":0.3002463525963699,"score_spread":0.297052241531767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7111891364","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8863406,0.0024628735,0.00080763065,0.0044713956,0.0005060499,0.00027944992,0.00000800258,0.00023911994,0.10488484],"genre_scores_gemma":[0.94737124,0.00014037342,0.00045381064,0.007972269,0.0003054798,0.000027626325,0.000017675531,0.000017890465,0.043693617],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992426,0.000040574017,0.0001479721,0.00019173688,0.0001390541,0.00023806063],"domain_scores_gemma":[0.9993934,0.00008138522,0.000026078042,0.00035232495,0.000033481425,0.00011333241],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00012481281,0.000118748714,0.0001970355,0.00008382244,0.000057481422,0.000015998543,0.000098493736,0.00010988031,0.0013118205],"category_scores_gemma":[0.0000997207,0.000102610284,0.00011660269,0.00017569779,0.00003774752,0.000045905508,0.00003825032,0.00015521613,0.00020493308],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033240174,0.0021619133,0.11085054,0.00079782004,0.0026547809,0.0010969832,0.006528756,0.00005896107,0.0844002,0.111100234,0.56129766,0.115728125],"study_design_scores_gemma":[0.005091365,0.00023786454,0.39074013,0.00025133963,0.0004114582,0.000037812613,0.00044272793,0.00050236174,0.037216324,0.010354004,0.55443656,0.0002780702],"about_ca_topic_score_codex":0.000036437094,"about_ca_topic_score_gemma":0.0000029829748,"teacher_disagreement_score":0.27988958,"about_ca_system_score_codex":0.00010308605,"about_ca_system_score_gemma":0.00029505332,"threshold_uncertainty_score":0.9996011},"labels":[],"label_agreement":null},{"id":"W7113726656","doi":"","title":"Dysregulation of Inositol Polyphosphate 5-Phosphatase OCRL in Alzheimer’s Disease: Implications for Autophagy Dysfunction","year":2025,"lang":"en","type":"article","venue":"Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; Institute of Genetics; National Institutes of Health; Fondation Médicale Reine Elisabeth; Fondation pour la Recherche sur Alzheimer; Koning Boudewijnstichting; Université de Liège; University of Pennsylvania; China Scholarship Council; Centre Hospitalier Universitaire de Rennes; Fonds De La Recherche Scientifique - FNRS; Centre Hospitalier Régional Universitaire de Montpellier; Rush University; Fondation pour l'Aide à la Recherche sur la Sclérose en Plaques; Association France Parkinson; University of Pittsburgh; University of Miami","keywords":"Autophagy; Inositol; Polyphosphate; Inositol phosphate","score_opus":0.01209300474992897,"score_gpt":0.2473670870103435,"score_spread":0.23527408226041452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7113726656","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88687694,0.02396588,0.07192566,0.008944729,0.00052514096,0.0027279144,0.0010533449,0.0005753179,0.0034050571],"genre_scores_gemma":[0.9910557,0.0015835633,0.002925701,0.0011014119,0.00013657066,0.000050177885,0.0010320732,0.00005993028,0.00205485],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"observational","domain_scores_codex":[0.99741244,0.00013994762,0.0005636575,0.00077647023,0.00028972412,0.00081772864],"domain_scores_gemma":[0.9977024,0.00021672138,0.00034790242,0.0008377232,0.00029492378,0.00060032646],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002616319,0.00050798,0.0006521737,0.0010164795,0.0007043529,0.000060778522,0.0006301535,0.00046015295,0.00021333981],"category_scores_gemma":[0.00007558858,0.0006181865,0.0005069811,0.0016685944,0.00036647212,0.0009933898,0.00024004406,0.00036783106,0.000021924894],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.03527317,0.0038828356,0.17867252,0.0014144406,0.0027200866,0.0011145355,0.0054449327,0.016163986,0.015315663,0.5934017,0.060101926,0.086494245],"study_design_scores_gemma":[0.022688055,0.0003346771,0.86315054,0.0009699778,0.0022595043,0.00011331113,0.002771058,0.019602718,0.021263108,0.0068664975,0.0591033,0.0008772693],"about_ca_topic_score_codex":0.0005690858,"about_ca_topic_score_gemma":0.00012091674,"teacher_disagreement_score":0.684478,"about_ca_system_score_codex":0.0009877296,"about_ca_system_score_gemma":0.002124099,"threshold_uncertainty_score":0.99962693},"labels":[],"label_agreement":null},{"id":"W7117471421","doi":"10.1242/dmm.052770","title":"First person – Camille Lacarrière-Keïta","year":2025,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"First person; Selection (genetic algorithm); Expression (computer science); Autophagy; Enteroendocrine cell","score_opus":0.019139763001385587,"score_gpt":0.2634243803403835,"score_spread":0.24428461733899792,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117471421","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.60410404,0.012332664,0.3285023,0.009555017,0.0014062118,0.0025321133,0.00036124044,0.0011753271,0.040031087],"genre_scores_gemma":[0.9865712,0.00018707982,0.000849668,0.004850215,0.000105683815,0.00016200691,0.00010541271,0.00004514658,0.0071235956],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9984536,0.000034265016,0.00021373997,0.0005043915,0.00038909234,0.00040488222],"domain_scores_gemma":[0.99861944,0.000029644421,0.00004985202,0.00068040576,0.00010384498,0.00051679346],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010591572,0.0002788989,0.00034351967,0.00017436215,0.00023228751,0.00003399379,0.00018914166,0.00011234201,0.00048605795],"category_scores_gemma":[0.000030354033,0.0002534785,0.00030700845,0.00025912124,0.000047676123,0.00013701261,0.000056577752,0.00015800155,0.0001010237],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002899594,0.0016634752,0.0005534092,0.0008988172,0.00090187014,0.0010249058,0.0010493376,0.0026126925,0.0044712783,0.9633198,0.014261461,0.0063434085],"study_design_scores_gemma":[0.009038017,0.00036446346,0.00909839,0.0011294286,0.0021026973,0.000015106711,0.0012571043,0.35341716,0.012903682,0.6002767,0.009279165,0.001118109],"about_ca_topic_score_codex":0.000046803892,"about_ca_topic_score_gemma":0.0000058249066,"teacher_disagreement_score":0.38246715,"about_ca_system_score_codex":0.00010936659,"about_ca_system_score_gemma":0.00031340308,"threshold_uncertainty_score":0.9999918},"labels":[],"label_agreement":null},{"id":"W7117725431","doi":"10.1080/15548627.2025.2610452","title":"PEX14 powers OPTN (optineurin) to drive peroxisome turnover","year":2025,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"KU Leuven","keywords":"Autophagy; Peroxisome; Organelle; Transport protein; Receptor; Membrane protein","score_opus":0.006753904845703569,"score_gpt":0.2950704810547024,"score_spread":0.2883165762089988,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117725431","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9308309,0.0011204794,0.00040792933,0.0034202775,0.0007205012,0.00054122735,0.000013027248,0.0002637954,0.06268185],"genre_scores_gemma":[0.95085496,0.000046344237,0.00052236865,0.013019457,0.00019413918,0.000052678228,0.000019074443,0.000032371758,0.035258617],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.99856037,0.000031704396,0.00028494975,0.00043830424,0.00027059362,0.00041410155],"domain_scores_gemma":[0.9989093,0.00006344983,0.000046699442,0.0006021911,0.000098344935,0.0002800302],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009954068,0.00023997076,0.0003696601,0.0002543314,0.000095323245,0.000030811974,0.0002008035,0.0001202515,0.0012785388],"category_scores_gemma":[0.000095300835,0.00021348102,0.00019686553,0.00046726942,0.000064075095,0.00009152903,0.00009671029,0.0002146023,0.00065707765],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004567525,0.004332814,0.03012228,0.0008610833,0.003407774,0.0042933873,0.006081909,0.00033040755,0.33988854,0.11127057,0.39779526,0.09704845],"study_design_scores_gemma":[0.006028936,0.0008693395,0.4299701,0.000326729,0.00034466616,0.000079016296,0.0003249358,0.00028585698,0.1993046,0.0017517039,0.3600842,0.00062992255],"about_ca_topic_score_codex":0.000026871892,"about_ca_topic_score_gemma":0.0000022876538,"teacher_disagreement_score":0.3998478,"about_ca_system_score_codex":0.000106450854,"about_ca_system_score_gemma":0.00020677784,"threshold_uncertainty_score":0.99963444},"labels":[],"label_agreement":null},{"id":"W7123679999","doi":"10.1134/s1819712425700849","title":"The Effect of Trehalose on Autophagy Gene Transcription and Ultrastructure in Neurons and Glia of 5-Month-Old db/db Mice, a Model of Type 2 Diabetes-Associated Neurodegeneration","year":2025,"lang":"en","type":"article","venue":"Neurochemical Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Western University","funders":"","keywords":"Trehalose; Autophagy; Neurodegeneration; Lipofuscin; Transcription factor; Neuroinflammation; Gene expression; Lipid droplet; Transcription (linguistics)","score_opus":0.0050091683360594715,"score_gpt":0.23882261481598968,"score_spread":0.23381344647993021,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7123679999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985478,0.00085893145,0.000015134574,0.00023469646,0.00010073437,0.00018759635,0.000015233553,0.0000065977233,0.000033298373],"genre_scores_gemma":[0.99912935,0.0005807503,0.000026945625,0.00018990114,0.000025531632,0.0000027209032,0.000006726096,0.000011602054,0.00002645922],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899703,0.00014529939,0.0003739677,0.00015170293,0.00018862943,0.0001433721],"domain_scores_gemma":[0.9993613,0.0002098461,0.00015747908,0.00012451124,0.00007367064,0.00007320776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001519376,0.00013434287,0.00033896643,0.00010012807,0.00004585729,0.000008915541,0.00007246566,0.00009880087,0.0000028742995],"category_scores_gemma":[0.00022135266,0.00009190759,0.000082585044,0.00018531323,0.00010418259,0.000039251103,0.000011082961,0.00035393966,4.8492193e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012649692,0.00010063157,0.009481575,0.00007835674,0.00005125635,0.0000059807944,0.00007100374,0.0002478569,0.9858403,0.00003397622,0.000050856215,0.0027731922],"study_design_scores_gemma":[0.002756116,0.0010610374,0.114207,0.00012583515,0.00015465022,0.0000111492855,0.0000038686635,0.014515219,0.86683923,0.00027678275,0.0000028551576,0.00004624127],"about_ca_topic_score_codex":0.0000026203013,"about_ca_topic_score_gemma":0.0000016134397,"teacher_disagreement_score":0.1190011,"about_ca_system_score_codex":0.000017975322,"about_ca_system_score_gemma":0.000048115162,"threshold_uncertainty_score":0.37478828},"labels":[],"label_agreement":null},{"id":"W7132863091","doi":"","title":"The Role of Lipid Transfer Proteins in Autophagy","year":2019,"lang":"","type":"dissertation","venue":"TSpace","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Amgen (Canada)","funders":"","keywords":"Autophagy; Lipid-anchored protein; Autophagosome; Phosphatidylinositol; Organelle; Ubiquitin; Phagosome; Membrane protein; ATG8","score_opus":0.008746647767590272,"score_gpt":0.3088454585544423,"score_spread":0.300098810786852,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7132863091","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9316444,0.03706967,0.000057593876,0.00032030905,0.0010480469,0.0033360652,0.000016011916,0.000029474111,0.026478462],"genre_scores_gemma":[0.94333917,0.004327871,0.000014564363,0.00008406426,0.00032527177,0.0002349468,0.00015169906,0.0001020244,0.05142037],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970899,0.00021381966,0.0008232617,0.00054335635,0.0006968816,0.0006327825],"domain_scores_gemma":[0.9982252,0.00024869686,0.00023879246,0.0009690352,0.0001440942,0.0001741668],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00044819902,0.000536242,0.0009345175,0.00021778308,0.00013607049,0.00002841603,0.00045770733,0.0005904936,0.0012745159],"category_scores_gemma":[0.00009278307,0.00039757814,0.00041863834,0.00045878792,0.00015137701,0.000074373194,0.00001769617,0.0008264635,0.00029069302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.013740098,0.0027593733,0.0025437418,0.002690928,0.0017317872,0.00010596893,0.15153976,0.00011070597,0.6678699,0.025577439,0.0001528999,0.13117735],"study_design_scores_gemma":[0.0054238834,0.0012968901,0.02741629,0.0022478164,0.00045808946,0.000005805546,0.049017254,0.0013927978,0.8707178,0.00080536556,0.040559914,0.00065808784],"about_ca_topic_score_codex":0.00050091726,"about_ca_topic_score_gemma":0.00015800915,"teacher_disagreement_score":0.20284787,"about_ca_system_score_codex":0.000113324,"about_ca_system_score_gemma":0.0010639656,"threshold_uncertainty_score":0.9998476},"labels":[],"label_agreement":null},{"id":"W7133064888","doi":"","title":"Identifying Probiotics that Modulate Mitophagy in Models of Mitochondrial Dysfunction","year":2023,"lang":"","type":"dissertation","venue":"TSpace","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Mitophagy; Neuroprotection; Probiotic; Mitochondrion; Mechanism (biology); Saccharomyces boulardii; Function (biology); Model organism","score_opus":0.06053622082811027,"score_gpt":0.36001687244112146,"score_spread":0.2994806516130112,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7133064888","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9789618,0.005005578,0.0019745152,0.000095274474,0.010067091,0.0023182204,0.00002865343,0.0001523352,0.0013964801],"genre_scores_gemma":[0.95242435,0.0038479615,0.0005123097,0.000048614587,0.0009458694,0.00011194254,0.0012520675,0.00025725062,0.040599663],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9957807,0.00020030516,0.0011640916,0.001009483,0.001063216,0.00078219105],"domain_scores_gemma":[0.99736756,0.00017292496,0.0009730317,0.00091909827,0.00030817487,0.00025920477],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031577112,0.0007712256,0.0014176778,0.0009982692,0.00013488877,0.00005865779,0.0003447356,0.0010528906,0.00041915703],"category_scores_gemma":[0.000117500465,0.0008242511,0.0005532997,0.0010876862,0.0001153778,0.00030967282,0.00006810911,0.00092211453,0.00021736184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.030609965,0.0044309273,0.003315093,0.022863263,0.0049309526,0.0016680006,0.2408861,0.057868082,0.60894823,0.0029305923,0.002530165,0.019018644],"study_design_scores_gemma":[0.027144728,0.0021693925,0.05129096,0.020863844,0.0035224627,0.00003281866,0.09677142,0.1508242,0.62014484,0.02402154,0.00015165121,0.0030621088],"about_ca_topic_score_codex":0.0009778166,"about_ca_topic_score_gemma":0.00032378506,"teacher_disagreement_score":0.14411469,"about_ca_system_score_codex":0.00030053037,"about_ca_system_score_gemma":0.0006010209,"threshold_uncertainty_score":0.9994208},"labels":[],"label_agreement":null},{"id":"W7133095259","doi":"","title":"The role of autophagy in innate immunity to intracellular bacterial pathogens","year":2008,"lang":"","type":"dissertation","venue":"TSpace","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"Phagosome; Autophagy; Vacuole; Intracellular parasite; Listeria monocytogenes; Salmonella enterica; Innate immune system; Population; Intracellular","score_opus":0.009851759488047772,"score_gpt":0.30041534828629707,"score_spread":0.2905635887982493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7133095259","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9712343,0.02183088,0.00000981347,0.0002117098,0.0015418271,0.0014803467,0.000044743596,0.000038876762,0.0036074722],"genre_scores_gemma":[0.9826385,0.009377408,0.00007012142,0.00010034855,0.00049514923,0.00012584632,0.00057031994,0.00011006152,0.0065122778],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963519,0.0005073042,0.0011205369,0.0005585974,0.0006683643,0.00079328456],"domain_scores_gemma":[0.99712545,0.00030576647,0.00062275166,0.0012765862,0.00030633397,0.00036311868],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006578905,0.00064536335,0.0010821394,0.00034504067,0.00037542958,0.0000386081,0.00064059877,0.0006223406,0.0010661312],"category_scores_gemma":[0.0004027276,0.00053587876,0.00035835966,0.0006327405,0.00020510868,0.00007432605,0.000098576784,0.00097234023,0.00019467778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0065771043,0.0008789474,0.00058117753,0.00020483267,0.0004369986,0.00028672992,0.075820476,0.000041263636,0.873404,0.0004947767,0.00012311684,0.041150548],"study_design_scores_gemma":[0.0033082436,0.0009871867,0.06514646,0.0009103593,0.0003302345,0.00002395719,0.03254167,0.0003894285,0.8627647,0.00048321302,0.03239727,0.00071728684],"about_ca_topic_score_codex":0.0014893131,"about_ca_topic_score_gemma":0.00033818692,"teacher_disagreement_score":0.064565286,"about_ca_system_score_codex":0.00020483254,"about_ca_system_score_gemma":0.001019481,"threshold_uncertainty_score":0.99984705},"labels":[],"label_agreement":null},{"id":"W7133109252","doi":"","title":"Autophagy in the Susceptibility to Crohn&apos;s Disease","year":2022,"lang":"","type":"dissertation","venue":"TSpace","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"ATG16L1; Autophagy; Inflammation; Immune system; Programmed cell death; Disease; Intestinal mucosa; Ulcerative colitis; Cytokine; Inflammatory bowel disease","score_opus":0.03749080974342861,"score_gpt":0.42564568911681555,"score_spread":0.38815487937338694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7133109252","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9701866,0.009873407,0.000018640847,0.0041038636,0.001907637,0.0041946014,0.000113531416,0.000105963256,0.009495761],"genre_scores_gemma":[0.94435376,0.0006144758,0.000031382162,0.0059614023,0.00063666643,0.001068664,0.0016101691,0.000134056,0.045589447],"study_design_codex":"qualitative","study_design_gemma":"observational","domain_scores_codex":[0.9938461,0.0010103636,0.0009341318,0.0014743719,0.0016530888,0.0010819432],"domain_scores_gemma":[0.9956003,0.00048621843,0.00034738187,0.0024729779,0.00016936327,0.0009237757],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0013681274,0.00089591986,0.0010063582,0.0004580621,0.00059256266,0.00012055736,0.0011991784,0.00029967088,0.03852412],"category_scores_gemma":[0.0006976887,0.0007368428,0.0006342946,0.0015400896,0.000140352,0.00010902819,0.00015358436,0.0016176882,0.0008009313],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.057831712,0.01717837,0.025025932,0.0055777766,0.0015006277,0.020213252,0.77205235,0.0014718376,0.007786523,0.008980036,0.038341634,0.044039965],"study_design_scores_gemma":[0.0030799122,0.00093618763,0.8551022,0.00047450874,0.00091037987,0.000011320551,0.09179768,0.00036616132,0.0008523095,0.0010160857,0.04440455,0.0010487101],"about_ca_topic_score_codex":0.0013704202,"about_ca_topic_score_gemma":0.00067158986,"teacher_disagreement_score":0.8300763,"about_ca_system_score_codex":0.0006343995,"about_ca_system_score_gemma":0.0017347564,"threshold_uncertainty_score":0.99997705},"labels":[],"label_agreement":null},{"id":"W752674381","doi":"10.5287/ora-kz5bnxapw","title":"The role of ATF4 in hypoxia-induced cell death in cancer","year":2011,"lang":"en","type":"dissertation","venue":"Oxford University Research Archive (ORA) (University of Oxford)","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Integrated stress response; Apoptosis; Cancer cell; Hypoxia (environmental); Programmed cell death; ATF4; Cancer research; Biology; Effector; Cell biology; Unfolded protein response; Chemistry; Cancer; Messenger RNA; Genetics; Gene","score_opus":0.03127125639714688,"score_gpt":0.2876434289349123,"score_spread":0.2563721725377654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W752674381","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8688788,0.00072338857,0.000010928618,0.000082404935,0.0000673249,0.0008965143,0.00017031799,0.000019043224,0.1291513],"genre_scores_gemma":[0.9635691,0.016854182,0.00032268555,0.000008024846,0.000029686391,0.0000012382974,0.00034215333,0.00004036265,0.018832581],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9971219,0.00042080195,0.00027179744,0.0005732131,0.0008426043,0.000769696],"domain_scores_gemma":[0.99789095,0.00036563544,0.00032875952,0.00067858485,0.00043216464,0.00030391506],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00059903867,0.00031242173,0.00072706264,0.0015970271,0.0004005981,0.000009749306,0.0012150359,0.00034857204,0.00034126674],"category_scores_gemma":[0.000049814287,0.00033596295,0.0003517066,0.0010987305,0.0004275519,0.00023966114,0.00030941758,0.0014025675,0.0000064093565],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.106466636,0.008386007,0.4687086,0.0043361075,0.0025463137,0.0053585595,0.07562867,0.000068454145,0.09952953,0.04627002,0.0020497215,0.18065137],"study_design_scores_gemma":[0.008107664,0.001623815,0.79446167,0.0014461898,0.00029874133,0.0000044867506,0.10374953,0.00068334164,0.007938225,0.009470619,0.071548454,0.0006672579],"about_ca_topic_score_codex":0.013569434,"about_ca_topic_score_gemma":0.031343214,"teacher_disagreement_score":0.32575306,"about_ca_system_score_codex":0.00041091713,"about_ca_system_score_gemma":0.0016453917,"threshold_uncertainty_score":0.9999092},"labels":[],"label_agreement":null},{"id":"W76547902","doi":"10.1016/b978-0-12-405881-1.00013-6","title":"Investigating the Role of Reactive Oxygen Species in Regulating Autophagy","year":2013,"lang":"en","type":"review","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Manitoba Health Research Council","keywords":"Autophagy; Reactive oxygen species; Chemistry; Cell biology; Biology; Biochemistry; Apoptosis","score_opus":0.10919583384027508,"score_gpt":0.46487965423831024,"score_spread":0.35568382039803514,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W76547902","genre_codex":"review","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011054054,0.97258323,0.0014904329,0.0002191358,0.0013634008,0.0038173238,0.000034877892,0.00012679449,0.009310765],"genre_scores_gemma":[0.00034182228,0.38810417,0.6080941,0.0006784926,0.00041353115,0.0013405357,0.00008305667,0.0002433698,0.0007009318],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9610689,0.030562121,0.004190247,0.0020102446,0.0004800509,0.0016883961],"domain_scores_gemma":[0.97151077,0.023124931,0.0024731632,0.0024028528,0.00019568362,0.00029258823],"candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.015161841,0.0015454794,0.007819996,0.0026815382,0.00015747752,0.000027005543,0.0014892211,0.0029925935,0.0006261163],"category_scores_gemma":[0.01151296,0.001169854,0.0009909323,0.002705943,0.0021091443,0.00015294713,0.000662641,0.005103644,0.00003768907],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014135172,0.0006682407,0.0009115641,0.0024027245,0.00051281904,0.00030843716,0.0020829767,0.000045726265,0.007967578,0.013724297,0.00007523793,0.97115904],"study_design_scores_gemma":[0.0072964495,0.003007399,0.071406774,0.024521887,0.002126941,0.0029798103,0.0033795193,0.00059431576,0.015116297,0.25281075,0.61321443,0.0035454426],"about_ca_topic_score_codex":0.0007153331,"about_ca_topic_score_gemma":0.00019688281,"teacher_disagreement_score":0.9676136,"about_ca_system_score_codex":0.000942795,"about_ca_system_score_gemma":0.0010261529,"threshold_uncertainty_score":0.9997294},"labels":[],"label_agreement":null},{"id":"W820716646","doi":"10.1371/journal.pone.0131068","title":"Autophagy-Associated Atrophy and Metabolic Remodeling of the Mouse Diaphragm after Short-Term Intermittent Hypoxia","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre; Christie (Canada)","funders":"Canadian Institutes of Health Research; McGill University Health Centre; McGill University","keywords":"Internal medicine; Endocrinology; Atrophy; Intermittent hypoxia; Calpain; Muscle atrophy; Sarcopenia; Biology; Myosin; Skeletal muscle; Myofibril; Downregulation and upregulation; Mitophagy; Autophagy; Cell biology; Medicine; Biochemistry; Apoptosis","score_opus":0.04792768566681428,"score_gpt":0.2509739869041551,"score_spread":0.20304630123734085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W820716646","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99483776,0.004182772,0.000013344055,0.00023513175,0.00004881688,0.00036800184,0.00002420584,0.000060212493,0.00022977349],"genre_scores_gemma":[0.9979897,0.0002805783,0.000289896,0.000498309,0.00011073341,0.000036240923,0.000010480403,0.00003369041,0.0007503531],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988002,0.00006582644,0.00028382716,0.0002112574,0.00042861624,0.0002102758],"domain_scores_gemma":[0.9991197,0.000023139604,0.00008272888,0.00041820595,0.00015988892,0.00019634815],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015062118,0.0001583105,0.00042103406,0.00006381105,0.00003550477,0.000013239981,0.000117895455,0.00008760331,0.000041483585],"category_scores_gemma":[0.0001088974,0.00010837853,0.00012499909,0.00013179306,0.00009807055,0.00007127125,0.00009834339,0.00017517242,0.0000097544635],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021912113,0.0093054855,0.28926927,0.00043661185,0.0053671785,0.00016313486,0.0055806837,0.000014749884,0.6773837,0.0003065083,0.00033551443,0.009645921],"study_design_scores_gemma":[0.0031433452,0.00030326928,0.69444543,0.0005151842,0.0019177261,0.000011121429,0.00011947355,0.002908793,0.29558912,0.0006861761,0.000068482695,0.00029183895],"about_ca_topic_score_codex":0.000016133632,"about_ca_topic_score_gemma":0.0000040321847,"teacher_disagreement_score":0.40517616,"about_ca_system_score_codex":0.000040523144,"about_ca_system_score_gemma":0.00006965048,"threshold_uncertainty_score":0.44195482},"labels":[],"label_agreement":null}]}