{"meta":{"query_hash":"a34c73639718","filters":{"topic":"Bioactive Compounds and Antitumor Agents"},"cohort_total":235,"direct_labels_cover":0,"predictions_cover":235,"exported":235,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/a34c73639718","api":"https://metacan.xera.ac/api/v1/cohort?topic=Bioactive+Compounds+and+Antitumor+Agents"},"results":[{"id":"W1483346783","doi":"10.1002/ptr.3503","title":"Shikonin Derivatives Protect Immune Organs from Damage and Promote Immune Responses <i>In Vivo</i> in Tumour‐bearing Mice","year":2011,"lang":"en","type":"article","venue":"Phytotherapy Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Department of Science and Technology of Jilin Province; University of Manitoba","keywords":"Immune system; CD19; Lymphocyte; Biology; Immunology; In vivo; Pharmacology; Natural killer cell; Cancer research; In vitro; Cytotoxic T cell; Biochemistry","score_opus":0.2805862298595079,"score_gpt":0.4663316924170993,"score_spread":0.18574546255759145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1483346783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918449,0.0031865733,0.00001967661,0.00066072773,0.00013044635,0.0010420881,0.00005797899,0.000041970932,0.0030156614],"genre_scores_gemma":[0.9966207,0.0014272487,0.0005440893,0.00017226912,0.00008560954,0.0001737559,0.0000052174573,0.000051745537,0.00091936544],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9959366,0.0020377303,0.00041776153,0.00055571675,0.00026078633,0.00079144514],"domain_scores_gemma":[0.9988417,0.00056803675,0.00009044225,0.0002626818,0.000102671474,0.00013448899],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0026516744,0.00025676747,0.00039075024,0.00042611716,0.00028226172,0.00005440914,0.00047594626,0.00021708537,0.0018361303],"category_scores_gemma":[0.00012504494,0.00024257196,0.000057123874,0.000730189,0.00056958495,0.00023853431,0.00021851904,0.0016102504,0.00003337364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030401594,0.0006599192,0.077153444,0.000038925347,0.00007500717,0.00016935672,0.0067533287,0.0000011555506,0.90849465,0.00017926349,0.00005528685,0.003379493],"study_design_scores_gemma":[0.002193341,0.00026985342,0.28405312,0.00011473417,0.0000048895054,0.0000051546135,0.0005317004,0.0002558959,0.7071956,0.0010033938,0.004146545,0.00022578568],"about_ca_topic_score_codex":0.0018714846,"about_ca_topic_score_gemma":0.00046118326,"teacher_disagreement_score":0.20689966,"about_ca_system_score_codex":0.000103880884,"about_ca_system_score_gemma":0.00012178567,"threshold_uncertainty_score":0.9990763},"labels":[],"label_agreement":null},{"id":"W1503237489","doi":"10.1023/a:1014478417580","title":"Suppression of Programmed Cell Death by Intracellular cAMP Is not Mediated by Expression of Genes Encoding an Inhibitor of Apoptosis","year":2002,"lang":"en","type":"article","venue":"Biochemistry (Moscow)","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Forskolin; Apoptosis; Cycloheximide; Biology; Programmed cell death; Cell biology; Signal transduction; Intracellular; DNA fragmentation; Molecular biology; Protein biosynthesis; Endocrinology; Biochemistry; Stimulation","score_opus":0.07049044269259917,"score_gpt":0.34711392511856565,"score_spread":0.27662348242596646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1503237489","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99523,0.0028771143,0.000036890946,0.000084184474,0.0002427697,0.00024350782,0.0008179441,0.000030613002,0.0004369686],"genre_scores_gemma":[0.9978361,0.00077653385,0.00040963982,0.00008131092,0.00008227305,0.000021403672,0.00026179448,0.00002622319,0.00050470995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99822223,0.00015528874,0.0005857871,0.0004080647,0.00028321397,0.00034542472],"domain_scores_gemma":[0.9986671,0.00011353018,0.00053471304,0.00029569474,0.00015745341,0.00023147669],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022094061,0.00027659532,0.00042974937,0.000044848046,0.000098874756,0.000008719205,0.0003623328,0.00049039884,0.0012460423],"category_scores_gemma":[0.000042078846,0.00025330472,0.00012306118,0.00016864545,0.0002751916,0.00008660804,0.00011845896,0.00030715787,0.000004818201],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002280451,0.0016870175,0.010751803,0.0004611834,0.00004899174,0.000002162332,0.00033492382,0.0000011461196,0.96356666,8.00279e-7,0.02178432,0.0011329531],"study_design_scores_gemma":[0.0012681442,0.00020438858,0.000035509365,0.00009560444,0.000086175685,0.0000015917987,0.00017842962,0.00052407023,0.98848265,0.0000024922485,0.008886011,0.00023490281],"about_ca_topic_score_codex":0.00002487341,"about_ca_topic_score_gemma":1.4639383e-7,"teacher_disagreement_score":0.024916027,"about_ca_system_score_codex":0.00003114304,"about_ca_system_score_gemma":0.000029895908,"threshold_uncertainty_score":0.9999919},"labels":[],"label_agreement":null},{"id":"W1528416445","doi":"10.1139/v01-127","title":"A synthesis of 6,11-disubstituted benzo[<i>b</i>]carbazoles","year":2001,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Isoquinoline; Methyllithium; Carbazole; Regioselectivity; Indole test; Sodium borohydride; Reagent; Stereochemistry; Tandem; Lithium aluminium hydride; Quinone; Lithium (medication); Borohydride; Medicinal chemistry; Organic chemistry","score_opus":0.07335526226652966,"score_gpt":0.35579086352508216,"score_spread":0.2824356012585525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1528416445","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98611426,0.0011441407,0.000023150382,0.0006398785,0.000469271,0.00003780056,0.00006789581,0.0000051766515,0.011498414],"genre_scores_gemma":[0.99880695,0.00017099881,0.00006661086,0.00023744711,0.00029156165,0.0000016464645,0.000003490163,0.000012522012,0.00040877255],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902934,0.000053374635,0.00039296804,0.000107093256,0.00010987807,0.00030733447],"domain_scores_gemma":[0.9985634,0.000115825234,0.00031033164,0.000120893485,0.00022278157,0.0006667602],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002707783,0.00014026913,0.00028695175,0.000085662505,0.00011731218,0.00001519074,0.00036270462,0.00019673465,0.002392724],"category_scores_gemma":[0.00016841835,0.00013450412,0.00016269943,0.00017445814,0.00028167275,0.000084479514,0.000012556242,0.00038490983,0.000007598221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002363087,0.00023705636,0.40282786,0.00021972608,0.00049387716,0.0021636635,0.0004269987,0.00017044794,0.559229,0.00014557289,0.02393492,0.009914594],"study_design_scores_gemma":[0.000749178,0.000024489382,0.009747368,0.00011539179,0.00016415992,0.0007919704,0.0002876364,0.00005336791,0.742086,0.00012829925,0.24564381,0.00020830828],"about_ca_topic_score_codex":0.0003151297,"about_ca_topic_score_gemma":0.0008602461,"teacher_disagreement_score":0.39308047,"about_ca_system_score_codex":0.00009033579,"about_ca_system_score_gemma":0.0007344014,"threshold_uncertainty_score":0.99851924},"labels":[],"label_agreement":null},{"id":"W1545045252","doi":"","title":"STUDIES ON THE T CELL SUPPRESSIVE AND ANTI-ANGIOGENIC ACTIVITIES OF THE DIETARY PHYTOCHEMICAL PIPERINE","year":2013,"lang":"en","type":"article","venue":"Library and Archives Canada (Government of Canada)","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Piperine; Phytochemical; Traditional medicine; Pharmacology; Chemistry; Medicine","score_opus":0.029478367762954726,"score_gpt":0.2538906057499982,"score_spread":0.2244122379870435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1545045252","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9719709,0.00084529875,3.3297866e-7,0.0067521962,0.00024953854,0.00019837204,0.00013342373,0.0000029520074,0.019846944],"genre_scores_gemma":[0.9949458,0.0004942883,0.000017960154,0.002587525,0.00004244955,0.000013797399,0.0000011890276,0.000008210719,0.0018887508],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898875,0.00013441395,0.00016625697,0.000144701,0.00038021101,0.000185663],"domain_scores_gemma":[0.99903136,0.00061646773,0.00013526742,0.0001257786,0.0000011531775,0.0000899789],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000013215954,0.00014140658,0.00019451915,0.000008364829,0.00022084457,0.000007402526,0.00019029653,0.000026489779,0.000080436395],"category_scores_gemma":[0.0000047344474,0.000082963816,0.000038478327,0.00004118849,0.00039947894,0.00010837378,0.00022401304,0.00020019985,4.151041e-9],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002632327,0.000101972786,0.05994679,0.00020097657,0.00039166876,0.000013359867,0.00039517216,0.00003192095,0.922807,0.006509091,0.008046872,0.001291952],"study_design_scores_gemma":[0.00022912576,0.000043525826,0.061488874,0.000034414395,0.000036042013,0.0000026730634,0.0030615958,0.00029122375,0.9308394,0.00036259077,0.0035101324,0.00010036983],"about_ca_topic_score_codex":0.00022115161,"about_ca_topic_score_gemma":0.00049917004,"teacher_disagreement_score":0.022974886,"about_ca_system_score_codex":0.0000028139236,"about_ca_system_score_gemma":0.00017778666,"threshold_uncertainty_score":0.33831662},"labels":[],"label_agreement":null},{"id":"W1581059395","doi":"10.6000/1929-2279.2015.04.02.1","title":"Bufalin Induces Apoptosis of MDA-MB-231 Cell Through Activation of JNK/p53 Pathway","year":2015,"lang":"en","type":"article","venue":"Journal of cancer research updates","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Bufalin; Apoptosis; MAPK/ERK pathway; Chemistry; Cancer research; Cancer; Breast cancer; Pharmacology; Internal medicine; Kinase; Biology; Medicine; Biochemistry","score_opus":0.4402836992531155,"score_gpt":0.5547447525320045,"score_spread":0.114461053278889,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1581059395","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992066,0.0025423118,0.000051194773,0.0017037501,0.00064671534,0.0001744615,0.00006995299,0.0000052668242,0.002740341],"genre_scores_gemma":[0.99634373,0.0024727166,0.0003294212,0.00014974149,0.00040438495,0.000008607733,0.000005926301,0.000017219116,0.0002682723],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973528,0.0007200188,0.0006341473,0.0001570591,0.00077263464,0.00036334546],"domain_scores_gemma":[0.9968167,0.00038157293,0.0006848011,0.0001420027,0.0017570901,0.0002178276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0023587209,0.00014359794,0.00040902797,0.00026542967,0.00010884752,0.000022234628,0.00048548295,0.00019541563,0.0005737582],"category_scores_gemma":[0.00020303605,0.00011265805,0.00013782945,0.00047297726,0.00040809237,0.00043397385,0.00012850705,0.0010471629,0.000010010762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001577358,0.00086683925,0.016771683,0.00016872499,0.00033085098,0.000010205485,0.0016529477,0.00022683112,0.94189245,0.00039069078,0.03107129,0.005040157],"study_design_scores_gemma":[0.0015823116,0.00055941526,0.0014352651,0.00010632756,0.000046598085,0.000003904908,0.0010515082,0.000043134532,0.9332491,0.0013873184,0.060435206,0.00009991128],"about_ca_topic_score_codex":0.00025690306,"about_ca_topic_score_gemma":0.000013906324,"teacher_disagreement_score":0.029363917,"about_ca_system_score_codex":0.00015465521,"about_ca_system_score_gemma":0.00069348246,"threshold_uncertainty_score":0.628225},"labels":[],"label_agreement":null},{"id":"W1590504688","doi":"10.1158/1538-7445.am2014-3804","title":"Abstract 3804: CPA-7, an inhibitor of STAT3, is a potent tumoricidal agent in peripheral tumor models and is impermeable to the CNS","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Survivin; Glioma; Cancer research; STAT3; Cisplatin; Apoptosis; Medicine; Biology; Chemistry; Molecular biology; Chemotherapy; Internal medicine; Biochemistry","score_opus":0.2743382566298365,"score_gpt":0.5091478968132257,"score_spread":0.23480964018338918,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1590504688","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99298227,0.00073411135,0.000040520434,0.0037544135,0.00033389343,0.0005754238,0.00017660987,0.000012413467,0.0013903697],"genre_scores_gemma":[0.99607646,0.00043315097,0.000042689517,0.0024393976,0.0003073435,0.00013697734,0.000004337902,0.000024684849,0.00053494435],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99772996,0.00043222378,0.00030131658,0.0004409003,0.00040923132,0.0006863755],"domain_scores_gemma":[0.998959,0.00013894176,0.00006351792,0.0002745297,0.00023333514,0.00033066445],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015918047,0.00017735931,0.00027080072,0.0001669771,0.00029754904,0.000055031196,0.00039767323,0.00009997453,0.0012883778],"category_scores_gemma":[0.000031937496,0.00013375422,0.00005783584,0.00035731954,0.00031356548,0.00016651549,0.00022357488,0.00085509,0.000024537463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033903173,0.0021152091,0.04872003,0.0006049748,0.00029961593,0.00016900204,0.031431347,0.0069483696,0.7209887,0.0018207023,0.09964417,0.08386756],"study_design_scores_gemma":[0.0071389494,0.0025336354,0.16806388,0.00036195214,0.00008869034,0.000038325637,0.005771003,0.08324131,0.45128837,0.0038429594,0.27639982,0.0012310991],"about_ca_topic_score_codex":0.0015126562,"about_ca_topic_score_gemma":0.00041754617,"teacher_disagreement_score":0.26970035,"about_ca_system_score_codex":0.00020031592,"about_ca_system_score_gemma":0.00019596846,"threshold_uncertainty_score":0.99962455},"labels":[],"label_agreement":null},{"id":"W1594745238","doi":"10.1186/1744-8069-3-2","title":"Progress and Future of Molecular Pain","year":2007,"lang":"en","type":"article","venue":"Molecular Pain","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Pain medicine; Neuroscience; Chronic pain; Cover (algebra); Molecular neuroscience; Feature (linguistics); Medicine; Cognitive science; Psychology; Bioinformatics; Biology; Psychiatry; Engineering; Anesthesiology","score_opus":0.03664009001477209,"score_gpt":0.38428225621900103,"score_spread":0.34764216620422894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1594745238","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9658459,0.008159208,0.021489182,0.0014563042,0.00033559828,0.00036089026,0.000015408934,0.000054882683,0.0022826246],"genre_scores_gemma":[0.9948988,0.00009676718,0.0014497623,0.003307014,0.00012813597,0.000010247208,0.00001642812,0.000024371322,0.000068490386],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99796885,0.0009602473,0.00025904505,0.0002728432,0.00016095431,0.0003780584],"domain_scores_gemma":[0.9993015,0.00015420797,0.00011122488,0.00017207535,0.00007727544,0.00018374373],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0039879335,0.00019046885,0.00021967437,0.00009875901,0.00009073267,0.000012724518,0.00016918161,0.00024245188,0.00014341269],"category_scores_gemma":[0.000058226782,0.0001814708,0.00009748591,0.00020265213,0.00027622454,0.00003374545,0.00007055594,0.0003304997,0.000005700789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021025736,0.0004244932,0.03670967,0.00017045517,0.0002557356,0.0009967108,0.0002951831,0.0000070747474,0.5484314,0.0069706882,0.001651127,0.4038772],"study_design_scores_gemma":[0.0017201575,0.0004719677,0.010502961,0.00004031454,0.00012731327,0.000036354657,0.0004240213,0.0011036366,0.6058949,0.0012424963,0.3779188,0.0005170143],"about_ca_topic_score_codex":0.0000046058963,"about_ca_topic_score_gemma":0.000003236314,"teacher_disagreement_score":0.4033602,"about_ca_system_score_codex":0.000019682251,"about_ca_system_score_gemma":0.000024270492,"threshold_uncertainty_score":0.7400164},"labels":[],"label_agreement":null},{"id":"W1759449679","doi":"10.4137/dti.s1146","title":"A Model for NAD(P)H: Quinoneoxidoreductase 1 (NQO1) Targeted Individualized Cancer Chemotherapy","year":2009,"lang":"en","type":"article","venue":"Drug Target Insights","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"CancerCare Manitoba Foundation; Welch Foundation","keywords":"Cancer research; Chemotherapy; Benzoquinone; NAD+ kinase; Medicine; Bone marrow; Pharmacology; Chemistry; Enzyme; Biochemistry; Immunology; Internal medicine","score_opus":0.12457566101711524,"score_gpt":0.43092028224312057,"score_spread":0.3063446212260053,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1759449679","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98101366,0.004087419,0.0025868795,0.0050927117,0.0017540543,0.0014085062,0.0007487994,0.00028911248,0.0030188493],"genre_scores_gemma":[0.9753218,0.000558758,0.0060240957,0.013383751,0.0005731324,0.00020110178,0.00030023485,0.000050027586,0.003587096],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99782723,0.00018364398,0.00044588526,0.00060008717,0.00023332817,0.0007098198],"domain_scores_gemma":[0.9988465,0.00011413062,0.00022227666,0.00027433372,0.00019725229,0.00034552044],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00029047494,0.00043752725,0.00050021417,0.00018241252,0.0005181223,0.00005111868,0.00044937033,0.00031384107,0.0009170782],"category_scores_gemma":[0.000028105243,0.00038577398,0.00025472377,0.00027846976,0.00015873631,0.0002468562,0.00003941568,0.0004964525,0.000039570314],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0042850045,0.0042533297,0.0025256735,0.0001638984,0.0012838043,0.00010094208,0.020917576,0.006058399,0.4528198,0.016648479,0.46334,0.027603095],"study_design_scores_gemma":[0.009051431,0.0001962849,0.0013213917,0.000036102727,0.00020969112,0.00001041713,0.00017179301,0.19443654,0.22041017,0.025834842,0.54725903,0.00106231],"about_ca_topic_score_codex":0.000026769518,"about_ca_topic_score_gemma":0.000030232028,"teacher_disagreement_score":0.23240963,"about_ca_system_score_codex":0.000114308605,"about_ca_system_score_gemma":0.00021377907,"threshold_uncertainty_score":0.99999624},"labels":[],"label_agreement":null},{"id":"W1798925125","doi":"10.1139/cjpp-2014-0032","title":"Vitronetcin promotes cell growth and inhibits apoptotic stimuli in a human hepatoma cell line via the activation of caspases","year":2014,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Apoptosis; Cell biology; Cell growth; Biology; Cell culture; Cell; Flow cytometry; Chemistry; Molecular biology; Biochemistry","score_opus":0.05103928470241917,"score_gpt":0.34514080647400186,"score_spread":0.29410152177158266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1798925125","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974382,0.0006617459,0.0000519976,0.00091020094,0.0004725793,0.00022579137,0.0000184862,0.000003928015,0.00021708927],"genre_scores_gemma":[0.9981434,0.00014944171,0.000040171548,0.0013318375,0.0002787527,0.0000049888345,0.000007575235,0.000014123804,0.000029731376],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980657,0.00084078114,0.00044864873,0.00020747997,0.000055637367,0.0003817325],"domain_scores_gemma":[0.998564,0.0005170153,0.00040074327,0.00007066297,0.00012751305,0.00032006446],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005231011,0.00020363019,0.00042266014,0.00027312653,0.00026855047,0.000008008063,0.00020531114,0.0002422587,0.00036075045],"category_scores_gemma":[0.000034429744,0.00015924666,0.000061627834,0.00016650764,0.00070948614,0.00011092397,0.000040773913,0.0007894492,0.000001735267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022048237,0.00018051702,0.013616693,0.00018619731,0.00006761024,0.00001960053,0.00062377495,0.00011560566,0.9837893,0.0001497771,0.00052794477,0.0005024882],"study_design_scores_gemma":[0.002592411,0.0010874569,0.01822245,0.000022823046,0.0001454829,0.000055129465,0.000083785475,0.0013808036,0.9737016,0.0015492813,0.0009896759,0.00016907546],"about_ca_topic_score_codex":0.0006975572,"about_ca_topic_score_gemma":0.00053284277,"teacher_disagreement_score":0.010087684,"about_ca_system_score_codex":0.000034267017,"about_ca_system_score_gemma":0.00018727119,"threshold_uncertainty_score":0.649389},"labels":[],"label_agreement":null},{"id":"W1846814999","doi":"10.1016/j.tiv.2015.09.029","title":"Antigenotoxic, anti-photogenotoxic and antioxidant activities of natural naphthoquinone shikonin and acetylshikonin and Arnebia euchroma callus extracts evaluated by the umu-test and EPR method","year":2015,"lang":"en","type":"article","venue":"Toxicology in Vitro","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Warszawski Uniwersytet Medyczny; University of Saskatchewan","keywords":"Genotoxicity; Chemistry; DPPH; Antioxidant; Cytotoxicity; Pharmacology; Apoptosis; Traditional medicine; Biochemistry; In vitro; Organic chemistry; Biology; Medicine; Toxicity","score_opus":0.09518259978800049,"score_gpt":0.4163275304472309,"score_spread":0.32114493065923044,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1846814999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9833412,0.013570188,0.00007252398,0.0011538701,0.0004468185,0.00089271343,0.00020302586,0.00004783763,0.0002717778],"genre_scores_gemma":[0.99584323,0.0018950547,0.00093739276,0.0008789368,0.0000839336,0.000055364988,0.000021679783,0.00004228009,0.00024212529],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99611944,0.0015039869,0.00060416415,0.00076541665,0.0002500438,0.00075696333],"domain_scores_gemma":[0.99719596,0.001713996,0.00035622317,0.00025882022,0.00010444652,0.00037057925],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002490164,0.0005081406,0.0009010925,0.00024136563,0.0003485111,0.000069699476,0.00026285893,0.00058021134,0.000053550655],"category_scores_gemma":[0.00034012776,0.00041115933,0.000059847032,0.00031424963,0.0019657959,0.0002819937,0.0003945782,0.001132887,0.0000026374757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008066727,0.0004375341,0.035085663,0.000084070845,0.00019691272,0.00012658791,0.0016139307,0.0000071592176,0.95422727,0.00011317885,0.00059186603,0.006709185],"study_design_scores_gemma":[0.006223673,0.0008427903,0.15858194,0.000051342602,0.00028227325,0.0014124614,0.001351431,0.0077241696,0.8206462,0.00037390375,0.0018711082,0.0006386761],"about_ca_topic_score_codex":0.00014269147,"about_ca_topic_score_gemma":0.00010783152,"teacher_disagreement_score":0.13358101,"about_ca_system_score_codex":0.00008036563,"about_ca_system_score_gemma":0.00014749145,"threshold_uncertainty_score":0.999834},"labels":[],"label_agreement":null},{"id":"W1907174366","doi":"10.5376/mpr.2013.03.0003","title":"Excision Wound Healing and Antioxidant Activity of Different Root Extract of &lt;i&gt;Plumbago indica&lt;/i&gt;","year":2013,"lang":"en","type":"article","venue":"Medicinal Plant Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Traditional medicine; Antioxidant; Wound healing; Chemistry; Biology; Medicine; Biochemistry; Immunology","score_opus":0.16812068556445167,"score_gpt":0.448551802212351,"score_spread":0.2804311166478993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1907174366","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99388754,0.0017835168,0.00011671484,0.0006801666,0.00028867327,0.0006472318,0.00009882306,0.000018509187,0.0024788333],"genre_scores_gemma":[0.99788105,0.001333122,0.000042978827,0.000040722414,0.00018963276,0.000029388662,0.000020037056,0.000017547713,0.0004455091],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9965402,0.0009365759,0.00048604095,0.00041561708,0.00093500986,0.00068654324],"domain_scores_gemma":[0.9974442,0.0014082668,0.00022933044,0.0002420211,0.00027670004,0.00039945566],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002407044,0.000234656,0.0005696187,0.0004158307,0.0003113458,0.00002601344,0.00035494592,0.00028959286,0.0015036121],"category_scores_gemma":[0.0002170599,0.0001762888,0.00008693942,0.00030374734,0.0010288147,0.00015709653,0.0002648921,0.001230719,0.000037012804],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007065216,0.0008965742,0.029350718,0.0003435235,0.0001369979,0.00007689539,0.00039461703,0.0000023753503,0.93246037,0.0004978336,0.0041826116,0.030950956],"study_design_scores_gemma":[0.0025680896,0.0014209229,0.7860472,0.0004484958,0.00008621913,0.00011769939,0.00019682093,0.003322181,0.18566193,0.00088519516,0.018948343,0.00029690348],"about_ca_topic_score_codex":0.0001676734,"about_ca_topic_score_gemma":0.00012250972,"teacher_disagreement_score":0.75669646,"about_ca_system_score_codex":0.000071967544,"about_ca_system_score_gemma":0.00012109901,"threshold_uncertainty_score":0.99940914},"labels":[],"label_agreement":null},{"id":"W1929646536","doi":"10.1016/j.jfluchem.2015.08.016","title":"2-(Fluoro-) and 2-(methoxyanilino)-1,4-naphthoquinones. Synthesis and mechanism and effect of fluorine substitution on redox reactivity and NMR","year":2015,"lang":"en","type":"article","venue":"Journal of Fluorine Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Catalysis; Carbon-13 NMR; Redox; Reactivity (psychology); Fluorine; Fluorine-19 NMR; Reaction mechanism; Proton NMR; Medicinal chemistry; Organic chemistry; Nuclear magnetic resonance spectroscopy","score_opus":0.07434108629151075,"score_gpt":0.38370065565041794,"score_spread":0.3093595693589072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1929646536","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99663746,0.0022393353,0.000030109533,0.0002680761,0.0002620639,0.00011900855,0.000026847902,0.00001167678,0.00040541432],"genre_scores_gemma":[0.99715555,0.0020766577,0.00035071687,0.000036963953,0.00027003617,0.0000043772334,0.0000021080052,0.00001539603,0.00008821167],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986949,0.00023251546,0.00039422806,0.0002703742,0.0001918804,0.00021609981],"domain_scores_gemma":[0.9982568,0.0006689118,0.00040012845,0.00012661054,0.00015956245,0.00038799815],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015685225,0.0002695877,0.00058704737,0.00007990985,0.000109477674,0.00002523918,0.00009987516,0.00025733717,0.000030354848],"category_scores_gemma":[0.00047768562,0.00021323244,0.000066626366,0.00009264263,0.00033518363,0.00017762225,0.00012258826,0.000607648,5.022513e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015470431,0.00016658416,0.024040617,0.00038576958,0.00018363603,0.00010149845,0.000101509446,0.000002674145,0.96171516,0.00012291389,0.00014141297,0.0114911515],"study_design_scores_gemma":[0.002529855,0.0005798706,0.007196108,0.00012531981,0.0002806828,0.0011061337,0.00007538192,0.00020702972,0.9854021,0.00031794287,0.0019864934,0.00019308373],"about_ca_topic_score_codex":0.000007924982,"about_ca_topic_score_gemma":6.0530806e-7,"teacher_disagreement_score":0.023686908,"about_ca_system_score_codex":0.00004956134,"about_ca_system_score_gemma":0.000050630526,"threshold_uncertainty_score":0.8695367},"labels":[],"label_agreement":null},{"id":"W1967899692","doi":"10.1021/jp802623r","title":"Nonlinear Phenomena in Light-Mediated Bromate−Hydroquinone−Benzoquinone Reactions","year":2008,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry A","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Bromate; Hydroquinone; Benzoquinone; Nonlinear system; 1,4-Benzoquinone; Chemistry; Photochemistry; Quinone; Inorganic chemistry; Physics; Organic chemistry","score_opus":0.07396369179682992,"score_gpt":0.3738759196964917,"score_spread":0.29991222789966177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967899692","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901309,0.0002321528,0.000012146143,0.0008068254,0.00011294187,0.00007215608,0.000017308392,0.00001699882,0.008598595],"genre_scores_gemma":[0.9971794,0.00026020833,0.000022271412,0.00021546887,0.0015951253,0.0000023760915,0.000005608021,0.000015198861,0.00070434506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988121,0.00017126389,0.00040213778,0.00011417962,0.00021033594,0.0002899859],"domain_scores_gemma":[0.99889266,0.00035303942,0.0003225052,0.00014758793,0.00010871505,0.00017550829],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036455086,0.00017281316,0.000311721,0.000037090536,0.0001912111,0.000007108146,0.00036252488,0.000112977286,0.00028843086],"category_scores_gemma":[0.00007096929,0.00011956958,0.00014832194,0.0002652158,0.0002362959,0.0001224286,0.000062554005,0.0010779473,0.000059230806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003813866,0.0013541515,0.00038814294,0.00003388588,0.000120123885,0.0001695158,0.00078714645,0.00057241786,0.9945672,0.000009259217,0.0014202428,0.00019653993],"study_design_scores_gemma":[0.0027922455,0.00024612574,0.0018439009,0.00006322482,0.00015272289,0.000929449,0.00029563456,0.008940523,0.8807381,0.00018503952,0.10351909,0.00029396144],"about_ca_topic_score_codex":0.000008511194,"about_ca_topic_score_gemma":9.698797e-7,"teacher_disagreement_score":0.113829106,"about_ca_system_score_codex":0.000079581405,"about_ca_system_score_gemma":0.0000890475,"threshold_uncertainty_score":0.48759058},"labels":[],"label_agreement":null},{"id":"W1968042102","doi":"10.1007/s11033-008-9356-7","title":"Dual role of shikonin in early and late stages of collagen type II arthritis","year":2008,"lang":"en","type":"article","venue":"Molecular Biology Reports","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Arthritis; Cartilage; Messenger RNA; Tumor necrosis factor alpha; Cytokine; Type II collagen; Medicine; Collagen-induced arthritis; Interleukin; Immunology; Inflammation; Endocrinology; Andrology; Internal medicine; Chemistry; Anatomy; Biochemistry","score_opus":0.047020964786226686,"score_gpt":0.3705367066876031,"score_spread":0.3235157419013764,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968042102","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941186,0.0041449894,0.000008608627,0.000059192575,0.00029021973,0.00017399227,0.000021990354,0.000012211059,0.0011702132],"genre_scores_gemma":[0.99876213,0.0007515224,0.00014729022,0.00010458661,0.000016018734,0.0000063999996,0.000018412626,0.000010524419,0.00018314304],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885184,0.00020991743,0.0004073146,0.00025469775,0.00005907529,0.0002171821],"domain_scores_gemma":[0.9994256,0.000039204726,0.00023801991,0.00014429487,0.000085267806,0.00006761658],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029105437,0.00012765231,0.00033121757,0.0001045018,0.00007705497,0.0000015895375,0.00005792725,0.00024524255,0.00011244949],"category_scores_gemma":[0.00005320485,0.0001253673,0.000051234667,0.00016859958,0.00046473317,0.00002745598,0.000119267694,0.00015426344,0.0000014529962],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000664614,0.000117928044,0.45483628,0.0000075659946,0.0000626036,0.0010665288,0.0002807381,0.000009615494,0.54250354,0.00015144565,0.000035589987,0.0008617016],"study_design_scores_gemma":[0.0008865697,0.0006608586,0.38956177,0.000024427569,0.00003556159,0.0006567718,0.000036191836,0.000029825653,0.60025024,0.0012300286,0.0064242263,0.00020353515],"about_ca_topic_score_codex":0.00008579993,"about_ca_topic_score_gemma":0.000016481004,"teacher_disagreement_score":0.0652745,"about_ca_system_score_codex":0.000009815343,"about_ca_system_score_gemma":0.00006631672,"threshold_uncertainty_score":0.51123303},"labels":[],"label_agreement":null},{"id":"W1971357574","doi":"10.1016/s0960-894x(02)00987-3","title":"A facile synthesis of C2-symmetric 17β-estradiol dimers","year":2003,"lang":"it","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Saint-François d'Assise; Université du Québec à Trois-Rivières","funders":"","keywords":"Chemistry; Chemical synthesis; Combinatorial chemistry; Stereochemistry; In vitro; Biochemistry","score_opus":0.06561764248673992,"score_gpt":0.34003376668094026,"score_spread":0.27441612419420036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971357574","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9764448,0.004404298,0.0001229328,0.0040724464,0.0021565247,0.0004168302,0.0003311951,0.000073710784,0.011977264],"genre_scores_gemma":[0.99485654,0.0012097324,0.000113491005,0.002309399,0.00059070287,0.00002617904,0.000034022043,0.000072261806,0.0007876746],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99592733,0.00051134743,0.0009732349,0.0008748889,0.00062694296,0.0010862652],"domain_scores_gemma":[0.9971963,0.00081192877,0.00063286885,0.0005378382,0.00013280904,0.00068825815],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00097225275,0.00074131216,0.0010124939,0.00017864905,0.0003101613,0.000028758846,0.000738492,0.00071462983,0.010375529],"category_scores_gemma":[0.00079499645,0.00073497137,0.00040196456,0.0010576515,0.0012366454,0.00010295248,0.00009565252,0.001424114,0.00018163014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019388061,0.0006933921,0.01159715,0.00078152015,0.001046232,0.00033603224,0.0002754138,0.0000055532514,0.9647897,0.000052982792,0.018157484,0.0020707],"study_design_scores_gemma":[0.0018935761,0.000088536275,0.0032724976,0.0002286755,0.0013200734,0.00029564183,0.00073847646,0.000056021967,0.92366177,0.000011686157,0.06773619,0.0006968457],"about_ca_topic_score_codex":0.000042346426,"about_ca_topic_score_gemma":7.0289855e-7,"teacher_disagreement_score":0.049578708,"about_ca_system_score_codex":0.0003204845,"about_ca_system_score_gemma":0.0003645737,"threshold_uncertainty_score":0.9995101},"labels":[],"label_agreement":null},{"id":"W1973407369","doi":"10.1016/j.freeradbiomed.2007.07.005","title":"Mechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin F","year":2007,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo; University of Manitoba","funders":"National Cancer Institute","keywords":"Glutathione; Chemistry; Cytotoxicity; Buthionine sulfoximine; Hydrogen peroxide; Catalase; DNA damage; Reactive oxygen species; Biochemistry; Peroxidase; Hydroxyl radical; Sulfoxide; Antioxidant; Radical; DNA; Stereochemistry; In vitro; Enzyme; Organic chemistry","score_opus":0.07265312980657405,"score_gpt":0.40403401712297315,"score_spread":0.3313808873163991,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973407369","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98998725,0.0012718482,0.0004473061,0.0036934027,0.0017094596,0.00033092426,0.000054392876,0.000013626149,0.0024917917],"genre_scores_gemma":[0.9976202,0.00029161628,0.000060621893,0.0015871221,0.00024338941,0.0000014636877,0.000003801512,0.0000074445634,0.00018429964],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985127,0.00037187836,0.00042482073,0.00023113527,0.00013276457,0.0003267121],"domain_scores_gemma":[0.99872714,0.00047357156,0.00026846392,0.00033917575,0.000059483493,0.00013215758],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0012698682,0.00016900848,0.0004162446,0.00005935994,0.00023012992,0.0000010846152,0.0005463208,0.00031403924,0.00022070795],"category_scores_gemma":[0.00044963983,0.00008285435,0.0001025069,0.00027300022,0.003503212,0.000021355996,0.00027005502,0.00057781173,0.000001979614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024663162,0.00026398903,0.17697735,0.00008147039,0.0001289194,0.0000114414015,0.0001808212,4.7122782e-7,0.73783034,0.080823675,0.0015325639,0.001922352],"study_design_scores_gemma":[0.0028303892,0.0004814706,0.36821568,0.00012332948,0.00021722956,0.00008445148,0.00009216733,0.00007807086,0.6104047,0.010338458,0.0069950297,0.00013907127],"about_ca_topic_score_codex":0.00006641069,"about_ca_topic_score_gemma":0.000045534467,"teacher_disagreement_score":0.19123833,"about_ca_system_score_codex":0.000016352347,"about_ca_system_score_gemma":0.000045898,"threshold_uncertainty_score":0.9992087},"labels":[],"label_agreement":null},{"id":"W1974973003","doi":"10.1371/journal.pone.0107149","title":"Fatty Acid Esters of Phloridzin Induce Apoptosis of Human Liver Cancer Cells through Altered Gene Expression","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Atlantic Canada Opportunities Agency; Faculty of Medicine, Dalhousie University; Dalhousie University","keywords":"Phloretin; Cancer cell; Biochemistry; Apoptosis; Chemistry; Biology; Molecular biology; Cancer","score_opus":0.25896367439714757,"score_gpt":0.39848887515477277,"score_spread":0.1395252007576252,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974973003","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99767226,0.00029828976,0.00017757663,0.00009626356,0.00036265136,0.00025163242,0.00010175361,0.00002543504,0.0010141105],"genre_scores_gemma":[0.9969378,0.0005906544,0.0016085551,0.00040088143,0.00025691817,0.000032334705,0.00001768754,0.000022081862,0.00013309186],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986576,0.0002493696,0.00034180467,0.00027158312,0.00021482386,0.0002648173],"domain_scores_gemma":[0.99914944,0.000088694986,0.00030749862,0.00022737663,0.00013253407,0.000094457966],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019635551,0.00018243835,0.0004116656,0.000056795474,0.00012336532,0.000006089872,0.00027423556,0.00019773848,0.0008207913],"category_scores_gemma":[0.000015026274,0.00016926641,0.000091072594,0.00011407355,0.00021104365,0.00012092821,0.00012241604,0.00032379606,0.00001982642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000149159,0.0019424376,0.012653696,0.00026396493,0.00032670275,9.201338e-7,0.00071984954,0.000009761753,0.9826039,0.000056696656,0.0006669295,0.0006059947],"study_design_scores_gemma":[0.0010813193,0.0001982827,0.0030623486,0.00015735687,0.00028356447,2.5182067e-7,0.000040541625,0.00014461786,0.9944237,0.00006279641,0.0003723811,0.00017286105],"about_ca_topic_score_codex":0.000084655105,"about_ca_topic_score_gemma":0.0000071890013,"teacher_disagreement_score":0.011819792,"about_ca_system_score_codex":0.000033237404,"about_ca_system_score_gemma":0.000022556587,"threshold_uncertainty_score":0.8987089},"labels":[],"label_agreement":null},{"id":"W1975090633","doi":"10.1016/j.bmcl.2010.02.060","title":"Design, synthesis, and biological evaluation of a novel series of quercetin diacylglucosides as potent anti-MRSA and anti-VRE agents","year":2010,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Guelph","keywords":"Chemistry; DNA gyrase; Escherichia coli; Quercetin; In vitro; Stereochemistry; Antibacterial agent; Microbiology; Combinatorial chemistry; Antibiotics; Biochemistry; Biology; Gene","score_opus":0.1576320448530112,"score_gpt":0.3900674770453906,"score_spread":0.2324354321923794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975090633","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99663794,0.00045991744,0.000100382334,0.002116856,0.00025633821,0.00025303205,0.000043300504,0.00001925225,0.00011295797],"genre_scores_gemma":[0.9984793,0.00047295357,0.00035534293,0.00049907813,0.00014179536,0.000013347698,0.000015137571,0.000013771526,0.0000092832615],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985889,0.00017757482,0.0003559146,0.00033850467,0.00029157952,0.0002475349],"domain_scores_gemma":[0.9990442,0.00024968665,0.000255344,0.00015435499,0.00013611626,0.00016029965],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012047333,0.00022608228,0.00038646208,0.000041170457,0.000108712426,0.000009867174,0.00017405997,0.00026517373,0.0005792741],"category_scores_gemma":[0.0004588221,0.00018477096,0.00005039675,0.00011027394,0.00091951934,0.00006266454,0.0000930913,0.00040807045,0.000001976816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001231062,0.00023369261,0.030733716,0.0001384294,0.00013372533,0.000012334626,0.00018393327,0.0000024580897,0.96660763,0.000011334104,0.0003094196,0.0015101988],"study_design_scores_gemma":[0.0011802935,0.000047991598,0.08364893,0.000066408786,0.00030434912,0.000106440966,0.00023597438,0.00024329023,0.91359395,0.000015778394,0.00038691767,0.00016966357],"about_ca_topic_score_codex":0.000028967394,"about_ca_topic_score_gemma":9.693018e-7,"teacher_disagreement_score":0.05301369,"about_ca_system_score_codex":0.000023612454,"about_ca_system_score_gemma":0.000081809776,"threshold_uncertainty_score":0.7534742},"labels":[],"label_agreement":null},{"id":"W1979553293","doi":"10.1016/j.molimm.2005.10.006","title":"Granulocyte macrophage-colony stimulating factor reduces the affinity of SHP-2 for the ITIM of CLECSF6 in neutrophils: A new mechanism of action for SHP-2","year":2005,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"","keywords":"Protein tyrosine phosphatase; Phosphorylation; Phosphatase; Cell biology; Receptor; Activator (genetics); Repressor; Tyrosine phosphorylation; Biology; Biochemistry; Chemistry; Transcription factor; Gene","score_opus":0.17220757369728265,"score_gpt":0.44225392898342214,"score_spread":0.2700463552861395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979553293","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876069,0.001758391,0.006842562,0.0016831808,0.00058167876,0.0013130334,0.00013347025,0.0000147848095,0.00006602391],"genre_scores_gemma":[0.99819446,0.00024453615,0.00092645746,0.0003158203,0.00008246209,0.00010784281,0.000013994491,0.000025402102,0.00008901216],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99834985,0.00035831347,0.00057254,0.00025517162,0.00010270948,0.00036139635],"domain_scores_gemma":[0.99814564,0.00091418705,0.00047391257,0.00026295098,0.00016663808,0.000036697125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049881777,0.00020456569,0.00043493722,0.00011598611,0.00017084423,0.0000069121925,0.00046254037,0.00028567488,0.00013041624],"category_scores_gemma":[0.00018837437,0.00014820027,0.000259946,0.0002020025,0.00034945845,0.00006368509,0.00010591143,0.00039896573,0.0000018535005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014626372,0.0002883903,0.00020853996,0.00006564239,0.0003880208,0.0000023421046,0.00060276483,0.0014963001,0.9694842,0.003786562,0.000085994085,0.022128595],"study_design_scores_gemma":[0.0029658184,0.0006023813,0.004654267,0.000022945915,0.00018260798,0.000008217759,0.0002366062,0.0076802103,0.9789269,0.0017539075,0.002829671,0.00013646547],"about_ca_topic_score_codex":0.00010262561,"about_ca_topic_score_gemma":0.00005184842,"teacher_disagreement_score":0.021992128,"about_ca_system_score_codex":0.000050875235,"about_ca_system_score_gemma":0.00011158864,"threshold_uncertainty_score":0.6043431},"labels":[],"label_agreement":null},{"id":"W1982069658","doi":"10.1021/tx800423s","title":"Prostaglandin H Synthase-1-Catalyzed Bioactivation of Neurotransmitters, Their Precursors, and Metabolites: Oxidative DNA Damage and Electron Spin Resonance Spectroscopy Studies","year":2009,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Chemistry; DNA oxidation; Hydroxyl radical; Reactive oxygen species; Oxidative stress; Biochemistry; Metabolite; DNA damage; Autoxidation; Reactive intermediate; Oxidative phosphorylation; Horseradish peroxidase; Enzyme; Antioxidant; DNA; Catalysis","score_opus":0.2046262849334357,"score_gpt":0.5034220694851365,"score_spread":0.29879578455170075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982069658","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9846903,0.006054422,0.000011542929,0.008119207,0.00007693914,0.00075191114,0.000058608082,0.000023265045,0.00021380118],"genre_scores_gemma":[0.9946192,0.0045636157,0.00024293366,0.00034581136,0.00007783098,0.00006905553,0.000022115062,0.000014422015,0.000045005763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99725527,0.0008888516,0.00032782697,0.0005869557,0.00020454696,0.0007365365],"domain_scores_gemma":[0.99812776,0.0012427495,0.00011182381,0.00017895039,0.0001569013,0.0001818456],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013313213,0.0002484483,0.00053747284,0.00030474062,0.00014332765,0.000026025858,0.00024316498,0.00028951486,0.00002475077],"category_scores_gemma":[0.0005772748,0.00020880366,0.000046288267,0.0005354056,0.001443567,0.00018795619,0.00013453438,0.0011319076,0.0000015187743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013024968,0.0004657663,0.0038752486,0.000102902115,0.00007538339,0.000026728943,0.0007679664,3.118615e-7,0.9865199,0.0018452249,0.0004636755,0.0045544025],"study_design_scores_gemma":[0.0016490277,0.0006151266,0.018124908,0.00006418989,0.000022494785,0.000012118494,0.00029746926,0.00017812096,0.9715318,0.003961468,0.0033678995,0.00017535653],"about_ca_topic_score_codex":0.000006138699,"about_ca_topic_score_gemma":0.00000829826,"teacher_disagreement_score":0.014988073,"about_ca_system_score_codex":0.00011809968,"about_ca_system_score_gemma":0.00007804315,"threshold_uncertainty_score":0.8514766},"labels":[],"label_agreement":null},{"id":"W1984109058","doi":"10.1016/s0960-894x(00)00346-2","title":"4-Alkylidenyl glutamic acids, potent and selective GluR5 agonists","year":2000,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Therapure Biopharma (Canada)","funders":"","keywords":"Chemistry; Glutamic acid; Agonist; Pharmacology; Receptor; Glutamate receptor; AMPA receptor; Biochemistry; Stereochemistry; Amino acid; Medicine","score_opus":0.04208958669357008,"score_gpt":0.3492225250164096,"score_spread":0.3071329383228395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984109058","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9869579,0.0013441875,0.000036667836,0.00734357,0.00034831112,0.00018005572,0.000029398141,0.00010852672,0.0036513694],"genre_scores_gemma":[0.99005175,0.00070670235,0.00005701127,0.007219761,0.00072525046,0.000012835869,0.000040643532,0.00003338419,0.0011526657],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99822205,0.00010701667,0.00030743913,0.00054572365,0.00024821097,0.00056956965],"domain_scores_gemma":[0.99919766,0.00008841109,0.00009921664,0.00020299086,0.00004710487,0.00036459736],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00026586372,0.00034516703,0.0003312804,0.0000340624,0.00032774778,0.000033087355,0.00028823176,0.00026686664,0.004928184],"category_scores_gemma":[0.000036205896,0.00032102136,0.00008485671,0.00021475813,0.0005295837,0.00008603353,0.00006408509,0.0007956476,0.00015489821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002207624,0.00013187488,0.006375949,0.00007627778,0.00018927066,0.00024056686,0.0002866003,0.0000024738335,0.96679324,0.000005230038,0.011468484,0.014209283],"study_design_scores_gemma":[0.0032234825,0.00009687534,0.03488737,0.0000771315,0.00035595492,0.00086754514,0.00023970408,0.00023774459,0.80895215,0.000058719856,0.15027505,0.00072827784],"about_ca_topic_score_codex":0.00002981435,"about_ca_topic_score_gemma":0.0000021486646,"teacher_disagreement_score":0.15784109,"about_ca_system_score_codex":0.00016135693,"about_ca_system_score_gemma":0.00007363597,"threshold_uncertainty_score":0.9999242},"labels":[],"label_agreement":null},{"id":"W1986215736","doi":"10.1021/jo001523s","title":"Synthesis of (±)-Puraquinonic Acid:  An Inducer of Cell Differentiation","year":2001,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Ring (chemistry); Inducer; Derivative (finance); Stereochemistry; Organic chemistry; Biochemistry","score_opus":0.06782864204675101,"score_gpt":0.36155417069124557,"score_spread":0.2937255286444945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986215736","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99779516,0.00044229414,0.0000872319,0.00015733995,0.00018824675,0.000039754388,0.000009683706,0.0000043327286,0.0012759351],"genre_scores_gemma":[0.9988319,0.0007335376,0.000034780696,0.000045242654,0.00017234679,4.3295046e-7,0.000001700545,0.0000120161185,0.00016801008],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904627,0.0001593486,0.0004215502,0.000068323716,0.00016337416,0.00014115742],"domain_scores_gemma":[0.9987244,0.00017419065,0.0006924809,0.00015619687,0.00016845786,0.00008425193],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00050733483,0.00011123463,0.00024989396,0.000027258395,0.00006425142,0.0000044244753,0.00038564764,0.00014404976,0.0038032287],"category_scores_gemma":[0.000055964727,0.00007736283,0.00009539474,0.00013301519,0.00012803971,0.00008031014,0.00004937545,0.00042259722,0.000003925225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026362494,0.00046236138,0.0076474184,0.0000692127,0.00012583111,0.000007149828,0.00027165766,0.0000050819494,0.9897679,0.0000018531191,0.00015981692,0.001218057],"study_design_scores_gemma":[0.00058300624,0.00007026445,0.008064056,0.000026964994,0.00031072652,0.00014056433,0.0003778205,0.000040123945,0.9898772,0.00005418145,0.00038179877,0.00007325636],"about_ca_topic_score_codex":0.0000021454775,"about_ca_topic_score_gemma":0.0000010595405,"teacher_disagreement_score":0.0037993037,"about_ca_system_score_codex":0.000038433354,"about_ca_system_score_gemma":0.00008553914,"threshold_uncertainty_score":0.99710745},"labels":[],"label_agreement":null},{"id":"W1988213404","doi":"10.1159/000239442","title":"Purpurogallin Inhibits DNA Synthesis of Murine Fibrosarcoma L-929 and Human U-87 MG Glioblastoma Cells in vitro","year":2009,"lang":"en","type":"article","venue":"Chemotherapy","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"","keywords":"Fibrosarcoma; In vitro; DNA; Cell culture; Molecular biology; DNA synthesis; Chemistry; Cell; Biochemistry; Biology; Genetics","score_opus":0.041369056446350014,"score_gpt":0.36687157748348176,"score_spread":0.32550252103713173,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988213404","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99724674,0.00034874777,0.000011299944,0.00071742677,0.00013324036,0.0002650061,0.000056701592,0.000043051168,0.001177802],"genre_scores_gemma":[0.99769735,0.00040862852,0.00021361513,0.0011884865,0.00011639007,0.000010454547,0.000007999313,0.000022708156,0.00033438558],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987134,0.0001360218,0.00034871537,0.00032516202,0.00011839536,0.00035835686],"domain_scores_gemma":[0.9993735,0.0001372328,0.00014322784,0.00017312032,0.00004208691,0.00013085046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002562489,0.0002428828,0.0003924992,0.0001248025,0.00010627343,0.00001736516,0.00020351306,0.00022071315,0.00034506267],"category_scores_gemma":[0.0000115288385,0.00023578599,0.000090809925,0.00021126476,0.00020745659,0.00008657276,0.00003362615,0.00032276296,0.000012154716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007794719,0.0006750228,0.0018546242,0.00004394919,0.000048520178,0.000028716799,0.00023493383,0.0000031857855,0.9682017,0.00014487572,0.0013028082,0.026682224],"study_design_scores_gemma":[0.002175342,0.00026914268,0.012720065,0.00003642497,0.000021671276,0.000011308513,0.000032813357,0.00013968012,0.9637581,0.000322659,0.020298308,0.00021445985],"about_ca_topic_score_codex":0.000012186646,"about_ca_topic_score_gemma":0.000008426825,"teacher_disagreement_score":0.026467765,"about_ca_system_score_codex":0.00003968859,"about_ca_system_score_gemma":0.000022591013,"threshold_uncertainty_score":0.9615073},"labels":[],"label_agreement":null},{"id":"W1989526884","doi":"10.1038/sj.onc.1209251","title":"Regulation of p53 and suppression of apoptosis by the soluble guanylyl cyclase/cGMP pathway in human ovarian cancer cells","year":2005,"lang":"en","type":"article","venue":"Oncogene","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":81,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"University of Ottawa","keywords":"Soluble guanylyl cyclase; Biology; Apoptosis; Downregulation and upregulation; Carcinogenesis; Cancer research; Signal transduction; Cyclic guanosine monophosphate; Cell biology; Endocrinology; Cancer; Biochemistry; Nitric oxide; Gene; Guanylate cyclase","score_opus":0.07322262851504488,"score_gpt":0.3953192335258515,"score_spread":0.3220966050108066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989526884","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99626076,0.00095807394,0.000035861547,0.0006590867,0.00028261403,0.0001995224,0.000108161395,0.000008111574,0.0014877805],"genre_scores_gemma":[0.99836785,0.00036803517,0.00009259691,0.00021046457,0.00008680413,0.000017083457,0.000020485457,0.0000109008815,0.00082577043],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907964,0.00018200741,0.00028028307,0.00017266416,0.00010681248,0.00017857787],"domain_scores_gemma":[0.99951524,0.00007238676,0.00017998269,0.00013129161,0.00004693391,0.00005419335],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032138533,0.000112887436,0.00019306605,0.000048948586,0.000120282915,0.000005802819,0.00013371957,0.0001470258,0.0007949445],"category_scores_gemma":[0.000005295894,0.00008683445,0.00004463646,0.00011771902,0.00016534317,0.000071291186,0.000066141256,0.00018150415,0.000002456882],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000089086825,0.0002656693,0.0065591647,0.000025762174,0.00003891266,4.7121438e-7,0.00032221508,0.00017794756,0.97066665,0.00015854319,0.0047218865,0.016973682],"study_design_scores_gemma":[0.0011058055,0.000053514934,0.0043812576,0.00003135056,0.000033913453,0.0000010564032,0.00004793256,0.0011341716,0.9593211,0.00007918704,0.033720106,0.00009061061],"about_ca_topic_score_codex":0.00021031231,"about_ca_topic_score_gemma":0.000102012644,"teacher_disagreement_score":0.02899822,"about_ca_system_score_codex":0.000038037615,"about_ca_system_score_gemma":0.00003292295,"threshold_uncertainty_score":0.8704085},"labels":[],"label_agreement":null},{"id":"W1992682420","doi":"10.1159/000220373","title":"Evidence for the Mode of Chemical Action of 1,4–Naphthoquinones in Bacteriostasis","year":2009,"lang":"en","type":"article","venue":"Chemotherapia","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Raytheon Technologies (Canada)","funders":"","keywords":"Icon; Citation; Subject (documents); World Wide Web; Action (physics); Library science; Computer science; Information retrieval; Physics","score_opus":0.33733902070367916,"score_gpt":0.510108302094641,"score_spread":0.17276928139096182,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992682420","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99702054,0.0008247804,0.00031277825,0.0012311343,0.00017104695,0.0002602074,0.000017668272,0.000009056058,0.0001527647],"genre_scores_gemma":[0.998364,0.00070569507,0.0002868256,0.00049725344,0.00006912989,0.0000120000195,0.000002635911,0.0000066207526,0.000055842716],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993909,0.00004750262,0.00021890733,0.0001302201,0.00006461085,0.00014787933],"domain_scores_gemma":[0.9992881,0.0003782407,0.0001243346,0.00012260281,0.000058554484,0.000028180573],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018495199,0.00009294778,0.00017726663,0.000040058712,0.00003082869,0.000003631366,0.00018470385,0.00011130452,0.0001829551],"category_scores_gemma":[0.000035313755,0.00006894533,0.00009255073,0.000108738575,0.00012337803,0.00006866845,0.000012319532,0.00014007068,0.0000012162583],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071693043,0.00020676953,0.004925585,0.000047250396,0.000044080312,3.3198788e-7,0.00034959483,0.000015274798,0.9278925,0.00023062942,0.0003239381,0.06524713],"study_design_scores_gemma":[0.0008590722,0.00009685186,0.01728468,0.000052244344,0.000032754393,0.0000024641522,0.000050557206,0.0013437965,0.9769116,0.0006078749,0.0026814863,0.00007658921],"about_ca_topic_score_codex":0.000012332476,"about_ca_topic_score_gemma":0.0000027505926,"teacher_disagreement_score":0.06517054,"about_ca_system_score_codex":0.000023091827,"about_ca_system_score_gemma":0.000025393425,"threshold_uncertainty_score":0.28115088},"labels":[],"label_agreement":null},{"id":"W1993578579","doi":"10.1139/o01-240","title":"Gene expression of immunomodulatory cytokines induced by <i>Narcissus tazetta</i> lectin in the mouse","year":2002,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Biology; Narcissus; Gene; Gene expression; Lectin; Genetics; Molecular biology; Cell biology; Botany","score_opus":0.06509922864941846,"score_gpt":0.34002208186165217,"score_spread":0.2749228532122337,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993578579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99089783,0.0058562006,0.00000414593,0.00021454786,0.00015328176,0.000114267204,0.000053321564,0.000013081134,0.0026933064],"genre_scores_gemma":[0.99782526,0.0007586245,0.00002852078,0.000512987,0.00007887125,0.000017612096,0.000055269506,0.000007957016,0.00071486604],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99897623,0.00022145755,0.00023748333,0.0002694824,0.00004786643,0.00024748372],"domain_scores_gemma":[0.9995042,0.00012020859,0.00012057642,0.00017336808,0.000026305082,0.0000553467],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023184289,0.0001650708,0.00019519127,0.000027375127,0.000116362186,0.0000067549868,0.0002465317,0.00035022234,0.0002363489],"category_scores_gemma":[0.000017830822,0.000121767545,0.000049552695,0.00010141664,0.00023569197,0.000024602286,0.00007097051,0.00036989638,0.000005381182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008039189,0.00036952877,0.0054439544,0.00003675586,0.000012700746,0.000005289381,0.00016930519,6.2700605e-7,0.9875181,0.000006729589,0.0046595796,0.0016970369],"study_design_scores_gemma":[0.00081961876,0.00009686628,0.0002836332,0.000004745577,0.000014845367,0.000010916271,0.00012356603,0.000036075817,0.9684867,0.000024654946,0.029962795,0.00013552773],"about_ca_topic_score_codex":0.000012048943,"about_ca_topic_score_gemma":6.9384794e-7,"teacher_disagreement_score":0.025303215,"about_ca_system_score_codex":0.000012817694,"about_ca_system_score_gemma":0.000009794874,"threshold_uncertainty_score":0.49655363},"labels":[],"label_agreement":null},{"id":"W1994270337","doi":"10.1107/s1600536801005049","title":"A novel chiral<i>C</i><sub>2</sub>axially symmetric acenaphthoquinone diketal","year":2001,"lang":"en","type":"article","venue":"Acta Crystallographica Section E Structure Reports Online","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"van der Waals force; Pentane; Chemistry; Envelope (radar); Moiety; Crystallography; Axial symmetry; Symmetry (geometry); Naphthalene; Crystal structure; Planar; Stereochemistry; Physics; Molecule; Geometry; Mathematics; Quantum mechanics; Organic chemistry","score_opus":0.04384467501015152,"score_gpt":0.34361450651412523,"score_spread":0.29976983150397374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994270337","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98978287,0.0004817716,0.0008546305,0.0009435836,0.0050331,0.0006648846,0.00030749553,0.0003531287,0.001578533],"genre_scores_gemma":[0.99408334,0.0015140757,0.00048957265,0.0012299216,0.0017419492,0.000023592307,0.0006147155,0.00009080849,0.00021200365],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961798,0.00023870645,0.0010187696,0.0010727949,0.0005617264,0.000928169],"domain_scores_gemma":[0.9975585,0.00014985705,0.00080600195,0.0005957321,0.00038081172,0.0005091358],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005061775,0.0006764018,0.00066809123,0.0009711127,0.00069621793,0.00009015207,0.00033162933,0.0008902357,0.00050585624],"category_scores_gemma":[0.00018528529,0.00061843847,0.00047384945,0.0025489437,0.00045861368,0.00040208438,0.00019551362,0.001755449,3.1881336e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033356948,0.0010144518,0.028833354,0.000042385884,0.0005385757,0.00087926525,0.000057664576,0.0000987984,0.96066576,0.000028884948,0.0011833812,0.006323906],"study_design_scores_gemma":[0.0027907651,0.0005800521,0.201788,0.000060507704,0.00061111903,0.016881911,0.00012232679,0.0005970203,0.009841524,0.0014488335,0.76392955,0.0013484114],"about_ca_topic_score_codex":0.000039662285,"about_ca_topic_score_gemma":0.0003251412,"teacher_disagreement_score":0.95082426,"about_ca_system_score_codex":0.00011242037,"about_ca_system_score_gemma":0.00014474789,"threshold_uncertainty_score":0.9996267},"labels":[],"label_agreement":null},{"id":"W1997360236","doi":"10.1073/pnas.1015258108","title":"Design, synthesis, and biological evaluation of a biyouyanagin compound library","year":2011,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Cancer Institute; Japan Society for the Promotion of Science; National Institute on Drug Abuse; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada","keywords":"Drug discovery; Lead compound; Combinatorial chemistry; Small molecule; Computational biology; Chemistry; Human immunodeficiency virus (HIV); Molecule; Nanotechnology; Modular design; Biology; Computer science; Biochemistry; Organic chemistry; Materials science; In vitro; Virology","score_opus":0.4993620276848994,"score_gpt":0.4524355318684172,"score_spread":0.04692649581648223,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997360236","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98869056,0.00041340478,0.0000022924849,0.00059941004,0.000027956425,0.00020512343,0.000015357353,0.000007197094,0.010038712],"genre_scores_gemma":[0.99799174,0.00014682968,0.001610709,0.00019539331,0.000024182678,0.000010619684,8.30727e-8,0.0000021836004,0.000018266437],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900466,0.000068938345,0.00023240954,0.00015735875,0.00043725307,0.000099402816],"domain_scores_gemma":[0.9991958,0.0002658288,0.00032496214,0.0000047871067,0.0001768602,0.000031766263],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0025396387,0.000071603296,0.0001351832,0.00010562336,0.00013075366,0.000006093693,0.0004110728,0.00010417094,0.00018613505],"category_scores_gemma":[0.00026047308,0.000044775123,0.00003894559,0.00031448173,0.0014164455,0.00027269172,0.00012399946,0.00013737724,6.873642e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020191606,0.0003835551,0.19824941,0.00008880858,0.000109352215,2.1236863e-8,0.00062597654,0.000028202921,0.75046986,0.044288024,0.0012973521,0.004257541],"study_design_scores_gemma":[0.00021195998,0.00005834699,0.22528434,0.00003417618,0.000052599713,0.0000057733,0.00011848356,0.0028446119,0.7258735,0.045315657,0.00014359714,0.000056995854],"about_ca_topic_score_codex":0.0000018917754,"about_ca_topic_score_gemma":8.502186e-9,"teacher_disagreement_score":0.027034925,"about_ca_system_score_codex":0.000008669584,"about_ca_system_score_gemma":0.00003338058,"threshold_uncertainty_score":0.52189523},"labels":[],"label_agreement":null},{"id":"W1998647759","doi":"10.1007/s11010-011-1040-x","title":"5,6-Dihydro-2H-pyranones and 5,6-dihydro-2H-pyridones and their derivatives modulate in vitro human T lymphocyte function","year":2011,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Infrastructure Canada","keywords":"In vitro; Lymphocyte; Function (biology); Chemistry; Clinical chemistry; Pharmacology; Biology; Immunology; Biochemistry; Cell biology","score_opus":0.04994861737679741,"score_gpt":0.3083939370392057,"score_spread":0.2584453196624083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998647759","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98902166,0.008378982,0.00047068912,0.00008434715,0.00014109173,0.00019941447,0.0000310187,0.000048702004,0.0016241247],"genre_scores_gemma":[0.9988973,0.00026959123,0.00009650159,0.00035952887,0.00006544252,0.000025613843,0.00006863449,0.000034569926,0.0001828163],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983966,0.0001601443,0.0002942399,0.0006054827,0.000093947616,0.00044963448],"domain_scores_gemma":[0.99935657,0.000033002143,0.00011436116,0.00020869014,0.0000401129,0.00024724327],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025875008,0.0003868933,0.00034580685,0.00009138599,0.00028587453,0.000042866883,0.00013752755,0.00035497834,0.000087309374],"category_scores_gemma":[0.000012242363,0.00035986918,0.00007792176,0.00013650554,0.0005117404,0.000093142065,0.00018774606,0.0003508522,0.0000030458427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034746417,0.00019019995,0.00816623,0.00014690415,0.00015136406,0.00011253886,0.00040453873,0.0000018715245,0.9874124,0.00013371899,0.000018036812,0.0029147465],"study_design_scores_gemma":[0.0017711413,0.00008532707,0.0022168737,0.000032491353,0.00008606785,0.00005250271,0.00034177094,0.0007150856,0.9924942,0.0011702774,0.0006236299,0.00041058773],"about_ca_topic_score_codex":0.000053427837,"about_ca_topic_score_gemma":0.000002958237,"teacher_disagreement_score":0.00987567,"about_ca_system_score_codex":0.00003349639,"about_ca_system_score_gemma":0.000027261958,"threshold_uncertainty_score":0.9998853},"labels":[],"label_agreement":null},{"id":"W1999544453","doi":"10.1039/b910133k","title":"Cytotoxicity of the traditional chinese medicine (TCM) plumbagin in its copper chemistry","year":2009,"lang":"en","type":"article","venue":"Dalton Transactions","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Plumbagin; Cytotoxicity; Chemistry; Metal; Copper; Ligand (biochemistry); Fluorescence; Stereochemistry; Topoisomerase; DNA; Nuclear chemistry; In vitro; Biochemistry; Organic chemistry; Receptor; Biology","score_opus":0.10700143043903076,"score_gpt":0.3912184001388898,"score_spread":0.28421696969985905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999544453","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9815007,0.00021207918,0.00024954948,0.005551562,0.0005604869,0.00023185705,0.00023130613,0.000029799456,0.011432683],"genre_scores_gemma":[0.9978601,0.000113529,0.00001540508,0.0010820038,0.00013864678,0.000013774332,0.000020125664,0.0000069298753,0.0007495193],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99904335,0.00011899354,0.00028673798,0.00018753046,0.00015678894,0.00020658592],"domain_scores_gemma":[0.9995193,0.00012153538,0.00008168119,0.00013617316,0.0000493465,0.000091972],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020652196,0.0001479787,0.0002099219,0.000048602422,0.00017981652,0.0000037952436,0.00022446658,0.00015730108,0.0032713371],"category_scores_gemma":[0.000022120486,0.00010690718,0.00010959716,0.00035406608,0.00022796553,0.00008468782,0.0000038340254,0.0006138352,0.000009192781],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021976525,0.0018541688,0.013022449,0.00008413873,0.00010355124,0.000016038717,0.00095696404,0.0007894139,0.97717166,0.00057171355,0.0025439768,0.0026661572],"study_design_scores_gemma":[0.004713039,0.00017122188,0.69199055,0.00010364301,0.00015129508,0.00008295649,0.00016998684,0.0036699395,0.283869,0.0015197713,0.013169342,0.0003892684],"about_ca_topic_score_codex":0.0000176506,"about_ca_topic_score_gemma":0.000030682822,"teacher_disagreement_score":0.6933027,"about_ca_system_score_codex":0.000054314212,"about_ca_system_score_gemma":0.000056028388,"threshold_uncertainty_score":0.99763983},"labels":[],"label_agreement":null},{"id":"W1999575823","doi":"10.1139/v10-106","title":"Reactions of toluquinone – cyclopentadiene Diels –Alder epoxide adducts with nucleophiles under heterogeneous conditions","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Epoxide; Cyclopentadiene; Chemistry; Nucleophile; Adduct; Sulfur; Organic chemistry; Diels–Alder reaction; Catalysis","score_opus":0.05207285412963607,"score_gpt":0.3524610069553192,"score_spread":0.3003881528256831,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999575823","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99205214,0.00018344495,0.000015301644,0.0009236783,0.00063210627,0.000064207525,0.00017319861,0.000005889466,0.005950038],"genre_scores_gemma":[0.9984203,0.000038430255,0.00013761899,0.0003421677,0.00028304008,0.0000026207606,0.000016343338,0.000018501234,0.0007409908],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909157,0.00003653342,0.0003434979,0.00013061023,0.000102624814,0.0002951493],"domain_scores_gemma":[0.9984362,0.00007378061,0.00033538396,0.00015418486,0.0002870575,0.000713368],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014601718,0.00014878101,0.00023823763,0.0000790302,0.00021369166,0.000021396118,0.00025220512,0.00018671737,0.004881849],"category_scores_gemma":[0.00003960088,0.00013371588,0.000102689024,0.000110318215,0.0005666985,0.000111403875,0.000012907583,0.0007589063,0.000010228713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006628595,0.00013018359,0.009276808,0.000050088274,0.00034611335,0.0004571327,0.00012885852,0.00027811076,0.9856385,0.00016688334,0.0032222911,0.00023876589],"study_design_scores_gemma":[0.0011922395,0.00009874689,0.010338366,0.0000689888,0.0001857032,0.0034751063,0.00029900824,0.0000147483615,0.90393674,0.00046001465,0.07967788,0.00025242538],"about_ca_topic_score_codex":0.00028879975,"about_ca_topic_score_gemma":0.0028338754,"teacher_disagreement_score":0.08170171,"about_ca_system_score_codex":0.0000621541,"about_ca_system_score_gemma":0.0006834633,"threshold_uncertainty_score":0.9960278},"labels":[],"label_agreement":null},{"id":"W1999687139","doi":"10.1021/jo7017075","title":"Synthesis of 4-Formyl Estrone Using a Positional Protecting Group and Its Conversion to Other C-4-Substituted Estrogens","year":2007,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Estrone; Chemistry; Yield (engineering); Hydroxymethyl; Estrogen; Dichloromethane; Triethylamine; Medicinal chemistry; Methyl group; Organic chemistry; Group (periodic table); Hormone; Solvent; Materials science; Biochemistry","score_opus":0.07499289086022692,"score_gpt":0.373308252233079,"score_spread":0.2983153613728521,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999687139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99788326,0.0002942276,0.0012673197,0.00017037895,0.00012026478,0.00009854669,0.000013238461,0.000005739248,0.0001470137],"genre_scores_gemma":[0.99916553,0.000029690902,0.00047510996,0.0001063197,0.0001901649,3.9528967e-7,4.9757637e-7,0.000011845654,0.000020438669],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99921304,0.000068455665,0.00031150627,0.00007818483,0.00014589763,0.00018291689],"domain_scores_gemma":[0.9990961,0.00025887965,0.00033023776,0.000062526946,0.00012131643,0.00013094908],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011170817,0.000109653745,0.00018031309,0.000034426208,0.00018455165,0.000006396786,0.00016707591,0.00010741253,0.00062906794],"category_scores_gemma":[0.00011361538,0.0000825062,0.00005531308,0.00013642208,0.00008677227,0.0000632282,0.0000616849,0.00042645136,0.00000240867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000508081,0.000107089385,0.002280958,0.00006189239,0.00015550443,0.000017595545,0.00019102958,0.00002308165,0.99625915,0.0000070825886,0.000020588459,0.00036793595],"study_design_scores_gemma":[0.0005441647,0.000043043416,0.0016049091,0.00008089284,0.00020272886,0.0007490067,0.00038285594,0.00018379526,0.9958168,0.000014028751,0.00029252976,0.00008522637],"about_ca_topic_score_codex":0.000003642661,"about_ca_topic_score_gemma":8.3060024e-7,"teacher_disagreement_score":0.0012822665,"about_ca_system_score_codex":0.000075555756,"about_ca_system_score_gemma":0.00005784534,"threshold_uncertainty_score":0.68878525},"labels":[],"label_agreement":null},{"id":"W2000704821","doi":"10.1016/s0223-5234(01)01294-6","title":"Cytotoxic 1,4-bis(2-oxo-1-cycloalkylmethylene)benzenes and related compounds","year":2002,"lang":"en","type":"article","venue":"European Journal of Medicinal Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Chemistry; Stereochemistry; Cytotoxic T cell; Benzene derivatives; Chemical synthesis; Benzene; Cytotoxicity; Melphalan; Cell culture; In vitro; Organic chemistry; Biochemistry; Chemotherapy","score_opus":0.09538352064319038,"score_gpt":0.3582120489853702,"score_spread":0.2628285283421798,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000704821","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91071796,0.008961479,0.00003608893,0.001450419,0.0008328848,0.000054513337,0.00000858894,0.000029611956,0.07790844],"genre_scores_gemma":[0.9936136,0.0021861338,0.00015825457,0.00060952676,0.000754621,4.6195066e-7,0.0000031650598,0.00003330295,0.0026409521],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980238,0.00048193196,0.0006612548,0.00021794987,0.00029391033,0.00032114825],"domain_scores_gemma":[0.9985788,0.00017985678,0.0004947669,0.00014491526,0.0001499728,0.00045167695],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0013114597,0.00024701594,0.00037056764,0.00007051574,0.00020341188,0.000027695382,0.00036897705,0.00011176811,0.0029099367],"category_scores_gemma":[0.00014244068,0.00020564748,0.00013854723,0.00014846525,0.00039806683,0.0001134844,0.00009268862,0.0012351113,0.00004691175],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027711957,0.00043865733,0.0069566756,0.00015447097,0.00053575897,0.0044040866,0.0009347047,0.000018673032,0.933171,0.000023392346,0.03156764,0.02151782],"study_design_scores_gemma":[0.015333482,0.0013803488,0.037049804,0.0007056006,0.0012713651,0.021377737,0.0014798944,0.0012933903,0.23560625,0.00021310542,0.6830901,0.0011989395],"about_ca_topic_score_codex":8.926108e-7,"about_ca_topic_score_gemma":1.4705448e-7,"teacher_disagreement_score":0.6975647,"about_ca_system_score_codex":0.000046326622,"about_ca_system_score_gemma":0.000027366645,"threshold_uncertainty_score":0.9980015},"labels":[],"label_agreement":null},{"id":"W2001382118","doi":"10.1002/jat.1483","title":"Cytotoxic effects of polychlorinated biphenyl hydroquinone metabolites in rat hepatocytes","year":2009,"lang":"en","type":"article","venue":"Journal of Applied Toxicology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Agency for Toxic Substances and Disease Registry; National Institute of Environmental Health Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Glutathione; Chemistry; Hydroquinone; Quinone; Autoxidation; Oxidative stress; Biochemistry; Metabolite; Toxicity; Benzoquinone; Semiquinone; Hepatocyte; Antioxidant; Organic chemistry; Enzyme","score_opus":0.04362732325351525,"score_gpt":0.36888756343294654,"score_spread":0.3252602401794313,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001382118","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929626,0.0018862243,0.0000644445,0.000524371,0.0013962011,0.00040907285,0.0000056964486,0.000020853511,0.0027305407],"genre_scores_gemma":[0.9969503,0.00070760027,0.00052086345,0.0014234456,0.00028047877,0.000011426482,0.0000028545169,0.000018970355,0.00008405036],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99779236,0.000286521,0.00089917984,0.0002535002,0.00022368447,0.00054477056],"domain_scores_gemma":[0.99805355,0.00059629907,0.00081813365,0.00017152516,0.00012762357,0.00023288408],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000772541,0.0003042951,0.0010088631,0.0005659784,0.00008309993,0.000012611801,0.00045779388,0.00044092943,0.00027454065],"category_scores_gemma":[0.00009329841,0.0002643199,0.00022069251,0.0005103667,0.00026376202,0.00013645414,0.00006337836,0.001009157,0.00001815815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020676658,0.001678383,0.0053589195,0.000070731636,0.00021701296,0.00046257308,0.00031506998,0.00013531336,0.97405857,0.005959183,0.0007255651,0.008951002],"study_design_scores_gemma":[0.0054316786,0.0014389801,0.020413633,0.000040427472,0.00019661267,0.00016898848,0.00007379761,0.00016853494,0.9569176,0.0036103541,0.011280535,0.00025885223],"about_ca_topic_score_codex":0.00000267365,"about_ca_topic_score_gemma":0.000004450172,"teacher_disagreement_score":0.017140975,"about_ca_system_score_codex":0.000107871085,"about_ca_system_score_gemma":0.00013904028,"threshold_uncertainty_score":0.9999809},"labels":[],"label_agreement":null},{"id":"W2009214751","doi":"10.5539/ijb.v5n3p1","title":"Antioxidant Activity and Immunomodulatory of Extracts From Roots of Actinidia kolomikta","year":2013,"lang":"en","type":"article","venue":"International Journal of Biology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Antioxidant; Nitric oxide; Actinidia; Chemistry; EC50; Apoptosis; Food science; Traditional medicine; Biochemistry; Botany; In vitro; Biology; Medicine","score_opus":0.07811565251477076,"score_gpt":0.41445154091054903,"score_spread":0.33633588839577827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009214751","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99608403,0.0008466754,0.00019087065,0.00046759754,0.0018095585,0.000068602036,0.00008084369,0.0000033005879,0.0004485267],"genre_scores_gemma":[0.9986661,0.00063244655,0.00031276618,0.00014025123,0.00020932648,0.000001269018,0.0000037403877,0.0000062462827,0.00002786726],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99898905,0.00021811905,0.00044567723,0.000113821225,0.00010927342,0.00012406669],"domain_scores_gemma":[0.9982075,0.0003836541,0.00081050297,0.000071596056,0.0004510771,0.00007567713],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002946967,0.00010731995,0.00030715953,0.00014415153,0.00002535521,0.000007003424,0.00030987232,0.00017001775,0.0006315512],"category_scores_gemma":[0.000096664175,0.000087748485,0.00010871265,0.000039154977,0.00028733345,0.00018404367,0.0000952178,0.00033369052,0.0000060657953],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003973249,0.0002901693,0.11375568,0.0000053590206,0.0005554368,0.000012305523,0.00007789856,0.000004323376,0.8506937,0.00028088398,0.00024401843,0.03368292],"study_design_scores_gemma":[0.0012623155,0.0002674735,0.7569396,0.000029047516,0.000045022964,0.00006591894,0.000049635168,0.00013930119,0.2360666,0.0014119649,0.0036432268,0.00007988504],"about_ca_topic_score_codex":0.00025488294,"about_ca_topic_score_gemma":0.000008856582,"teacher_disagreement_score":0.64318395,"about_ca_system_score_codex":0.000026483436,"about_ca_system_score_gemma":0.000064171094,"threshold_uncertainty_score":0.69150424},"labels":[],"label_agreement":null},{"id":"W2011903845","doi":"10.1139/y08-074","title":"<i>Leonurus sibiricus</i>induces nitric oxide and tumor necrosis factor-α in mouse peritoneal macrophages","year":2008,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Wonkwang University","keywords":"Pyrrolidine dithiocarbamate; Nitric oxide; Tumor necrosis factor alpha; Nitric oxide synthase; Stimulation; Chemistry; Immune system; Immunology; Pharmacology; Biology; NF-κB; Inflammation; Endocrinology","score_opus":0.07201891623740571,"score_gpt":0.3512448444462569,"score_spread":0.2792259282088512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011903845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99489224,0.002932337,0.0000019875492,0.0006895482,0.0010066708,0.00018565234,0.00011899635,0.00001107064,0.00016150229],"genre_scores_gemma":[0.99379784,0.001971873,0.00007004154,0.0034775909,0.00033873503,0.00000925332,0.000005416076,0.00002341246,0.00030586755],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977479,0.0006008002,0.0005309022,0.00033805438,0.000077612945,0.0007047482],"domain_scores_gemma":[0.9982646,0.00033668487,0.00030644482,0.00008345084,0.00014207597,0.0008667286],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00029544378,0.0003146886,0.00062200933,0.0005149535,0.0005109802,0.000015920357,0.0002885851,0.00032347965,0.0013871575],"category_scores_gemma":[0.000041224437,0.0002625698,0.00010345597,0.0002536461,0.0012042611,0.00022442116,0.000054423992,0.0012273167,0.000013440286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028866995,0.00012939914,0.094950326,0.000058099475,0.00017399689,0.0014237153,0.0006380485,0.000026303676,0.8975513,0.000041828407,0.003981287,0.0007370348],"study_design_scores_gemma":[0.004917468,0.0004952468,0.4584343,0.000019770057,0.00015209093,0.0027408262,0.00026695273,0.00013328918,0.5062311,0.00043200827,0.025610026,0.0005668693],"about_ca_topic_score_codex":0.00093977444,"about_ca_topic_score_gemma":0.0005886837,"teacher_disagreement_score":0.39132017,"about_ca_system_score_codex":0.00009382683,"about_ca_system_score_gemma":0.0005308937,"threshold_uncertainty_score":0.99998266},"labels":[],"label_agreement":null},{"id":"W2017171169","doi":"10.1371/journal.pone.0022510","title":"Shikonin Increases Glucose Uptake in Skeletal Muscle Cells and Improves Plasma Glucose Levels in Diabetic Goto-Kakizaki Rats","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Stockholms Universitet; Hospital for Sick Children; Medical Research Council; Vetenskapsrådet; National Health and Medical Research Council; Karolinska Institutet","keywords":"Glucose uptake; GLUT4; Internal medicine; Skeletal muscle; Endocrinology; Insulin; Glucose transporter; Glucose homeostasis; Myocyte; Carbohydrate metabolism; Chemistry; Snf3; Insulin resistance; Biology; Medicine","score_opus":0.1643071748128553,"score_gpt":0.33334361801465756,"score_spread":0.16903644320180225,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017171169","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99631286,0.001097802,0.0000018741146,0.00007653391,0.00018590645,0.0006171727,0.00012997533,0.000057298468,0.0015205743],"genre_scores_gemma":[0.9978034,0.00071133836,0.00055959506,0.0004570016,0.00009593964,0.00008999507,0.00001529784,0.0000378291,0.0002296291],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978378,0.000374799,0.00046214866,0.00050751155,0.00017828688,0.0006394886],"domain_scores_gemma":[0.9990908,0.0002534688,0.00013493924,0.00020953517,0.000051708837,0.00025956286],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048858486,0.0003232181,0.00048647943,0.00023165076,0.00012139763,0.000030309213,0.0002713071,0.0002980863,0.00076590246],"category_scores_gemma":[0.00008466769,0.0003268449,0.000064110005,0.00028495025,0.00029844607,0.00024101912,0.00019484133,0.0007271112,0.00011034509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019882584,0.007640966,0.06525492,0.00017306492,0.00018105023,0.00023943945,0.0010390214,0.0000016962568,0.9141326,0.00016425001,0.0000605555,0.010913621],"study_design_scores_gemma":[0.0024406041,0.0002525092,0.38633958,0.00010935173,0.00012017633,0.0000030668264,0.00015939282,0.0014063596,0.6079835,0.00027153417,0.0005505322,0.00036337483],"about_ca_topic_score_codex":0.00022437016,"about_ca_topic_score_gemma":0.00036086724,"teacher_disagreement_score":0.32108465,"about_ca_system_score_codex":0.00007585157,"about_ca_system_score_gemma":0.00006771169,"threshold_uncertainty_score":0.99991834},"labels":[],"label_agreement":null},{"id":"W2020407061","doi":"10.1016/j.jchromb.2014.07.028","title":"Development of a UPLC–MS/MS bioanalytical method for the pharmacokinetic study of (−)-epiafzelechin, a flavan-3-ol with osteoprotective activity, in C57BL/6J mice","year":2014,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Hong Kong Polytechnic University","keywords":"Chemistry; Chromatography; Formic acid; Pharmacokinetics; Cmax; High-performance liquid chromatography; Bioanalysis; Detection limit; Extraction (chemistry); In vivo; Quantitative analysis (chemistry); Elution; Gradient elution; Pharmacology","score_opus":0.07591936929000684,"score_gpt":0.42162291208774405,"score_spread":0.3457035427977372,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020407061","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9795517,0.00027264707,0.018342359,0.00025149534,0.00026810507,0.0010877323,0.000012837367,0.000008716046,0.00020440707],"genre_scores_gemma":[0.99043196,0.000052058313,0.009192907,0.000118681295,0.000100495046,0.000068530535,6.123297e-7,0.000024973575,0.000009759273],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99738795,0.000723164,0.00088103674,0.00024935938,0.00040643616,0.00035205268],"domain_scores_gemma":[0.99710935,0.001099137,0.0010755291,0.00017134275,0.00040056973,0.00014405749],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002392635,0.00028645963,0.00080922246,0.0005456629,0.00016316299,0.000016410537,0.0005018645,0.00017611611,0.00006962421],"category_scores_gemma":[0.00007188901,0.0001825444,0.00028703205,0.00078075647,0.00024053328,0.00012492068,0.000082391074,0.0009261883,7.313279e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.014347964,0.015480683,0.18064825,0.00086056354,0.009021029,0.0000743902,0.012837977,0.0010867009,0.66493315,0.0002986211,0.0007011286,0.09970956],"study_design_scores_gemma":[0.023758102,0.0061381543,0.20487411,0.00035612794,0.0022312324,0.00021691353,0.0027989603,0.010861284,0.733948,0.00040920253,0.013759726,0.0006481693],"about_ca_topic_score_codex":0.00004858062,"about_ca_topic_score_gemma":0.00017772612,"teacher_disagreement_score":0.09906139,"about_ca_system_score_codex":0.00004503483,"about_ca_system_score_gemma":0.00016367514,"threshold_uncertainty_score":0.7443945},"labels":[],"label_agreement":null},{"id":"W2022383336","doi":"10.1158/1538-7445.am2012-1077","title":"Abstract 1077: Bufalin inhibited cell proliferation and expression of insulin-like growth factor 2 and type 1 receptor in human colorectal cancer cells","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Bufalin; Insulin-like growth factor 1 receptor; Cell growth; Cell cycle; Insulin-like growth factor; Chemistry; Molecular biology; Flow cytometry; Receptor; Cell; Growth factor; Endocrinology; Internal medicine; Biology; Apoptosis; Biochemistry; Medicine","score_opus":0.1999447531325063,"score_gpt":0.48570431621688287,"score_spread":0.28575956308437656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022383336","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942859,0.004173884,9.0936095e-7,0.0001145672,0.0004962311,0.00048810823,0.00012087993,0.000012124081,0.00030741518],"genre_scores_gemma":[0.99525857,0.0040715793,0.000024136203,0.000070131166,0.00023696566,0.000089446774,0.000018554629,0.000018707306,0.00021193431],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99850273,0.0003561476,0.00024077744,0.00025282253,0.00021353265,0.00043401567],"domain_scores_gemma":[0.9992338,0.00016930778,0.00008772753,0.00006948575,0.00023191478,0.00020777018],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006767466,0.00013772896,0.00020079048,0.00019586063,0.0001945445,0.00002225737,0.00010637614,0.00023056027,0.0011352919],"category_scores_gemma":[0.000029215467,0.00012223712,0.0000201778,0.000290776,0.00029252665,0.000191961,0.00012229425,0.0007305868,0.000008211699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044634475,0.00025960442,0.19168767,0.00017995172,0.000012835423,0.0000017727587,0.0012035763,0.0000027207177,0.8032179,0.000019014356,0.0019341302,0.0010345101],"study_design_scores_gemma":[0.0010623995,0.000110544825,0.09925781,0.00007327333,0.000007391323,4.8696137e-7,0.00012870043,0.000027117127,0.89562017,0.000019551393,0.0035705606,0.00012197241],"about_ca_topic_score_codex":0.0004566152,"about_ca_topic_score_gemma":0.00011275394,"teacher_disagreement_score":0.09242987,"about_ca_system_score_codex":0.0001230022,"about_ca_system_score_gemma":0.00010764342,"threshold_uncertainty_score":0.9997778},"labels":[],"label_agreement":null},{"id":"W2024421129","doi":"10.1155/2015/751348","title":"Advances in the Research and Development of Natural Health Products as Main Stream Cancer Therapeutics","year":2015,"lang":"en","type":"review","venue":"Evidence-based Complementary and Alternative Medicine","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; University of Windsor","funders":"","keywords":"Cancer; Medicine; Cancer therapy; Disease; Cancer treatment; Intensive care medicine; Internal medicine","score_opus":0.7226954710158353,"score_gpt":0.6319151726244708,"score_spread":0.09078029839136448,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024421129","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0027057182,0.9891619,0.0000107383585,0.0057326998,0.0005962285,0.001605312,0.000108924345,0.000007326581,0.00007113871],"genre_scores_gemma":[0.019014439,0.9783833,0.00016941008,0.0015994387,0.00043291334,0.00018645135,0.00014641444,0.000017594115,0.00005002801],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9950979,0.0024340954,0.0008063895,0.0005463339,0.00063755544,0.00047777555],"domain_scores_gemma":[0.9971504,0.0017858376,0.00047706408,0.0002019097,0.00024180092,0.0001429559],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00506613,0.00039085923,0.0011068333,0.00032282918,0.0003398559,0.00001597453,0.00053585233,0.000062172716,0.00017113233],"category_scores_gemma":[0.00007487517,0.00022580237,0.000038254857,0.0004922618,0.0010909066,0.00016667088,0.00017023098,0.0012059249,0.0000024825524],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001795792,0.00021192603,0.0011856727,0.005966534,0.00018757692,0.000034768036,0.0024823297,0.0000013570871,0.000013884344,0.00031944722,0.0010748273,0.9883421],"study_design_scores_gemma":[0.0011962563,0.0008024846,0.00019117893,0.014191068,0.00013795697,0.000018444774,0.0013613754,0.000036782152,0.00008932269,0.0002926899,0.9814725,0.00020991861],"about_ca_topic_score_codex":0.0004238835,"about_ca_topic_score_gemma":0.00043663086,"teacher_disagreement_score":0.9881322,"about_ca_system_score_codex":0.00027639733,"about_ca_system_score_gemma":0.0011300987,"threshold_uncertainty_score":0.9207954},"labels":[],"label_agreement":null},{"id":"W2025424557","doi":"10.1139/y10-085","title":"Shikonin inhibits the proliferation and induces the apoptosis of human HepG2 cells","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Apoptosis; Annexin; Cell growth; Molecular biology; Cell biology; Cell cycle; Biology; Programmed cell death; Fragmentation (computing); Cancer cell; Fas receptor; Flow cytometry; Cell; MTT assay; Chemistry; Biochemistry; Cancer","score_opus":0.06374126087315204,"score_gpt":0.37148395003004714,"score_spread":0.30774268915689507,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025424557","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99300724,0.0005150852,0.0000018307605,0.003678907,0.002221719,0.00020635319,0.000028751918,0.0000031158293,0.00033698636],"genre_scores_gemma":[0.9964947,0.00018989225,0.000017860495,0.0026166774,0.00059617177,0.000008389455,0.0000029808737,0.000009451605,0.000063839056],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985692,0.00056308316,0.00035648653,0.0001520237,0.000055664146,0.0003035552],"domain_scores_gemma":[0.9987431,0.0003675607,0.00034709234,0.00008642256,0.00017099851,0.0002848107],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000791127,0.00015840537,0.00027960248,0.00012206886,0.0006973734,0.000016632845,0.0002980394,0.00026096258,0.0010007822],"category_scores_gemma":[0.000025781683,0.0000959385,0.00006761011,0.00011688363,0.0015548608,0.00009982237,0.000041427662,0.0013132669,0.000002937289],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000076241944,0.00004321505,0.0038298324,0.000029357296,0.00017667918,0.0000061858536,0.0010096871,0.000008305179,0.9878979,0.001437511,0.0044506514,0.0010344844],"study_design_scores_gemma":[0.0008730632,0.000304409,0.01358188,0.000006661787,0.00019968532,0.00008903245,0.00019252817,0.000046453326,0.96545446,0.0013671509,0.017770346,0.00011434203],"about_ca_topic_score_codex":0.00019734612,"about_ca_topic_score_gemma":0.0010748972,"teacher_disagreement_score":0.022443403,"about_ca_system_score_codex":0.000013229352,"about_ca_system_score_gemma":0.00027841504,"threshold_uncertainty_score":0.99991244},"labels":[],"label_agreement":null},{"id":"W2027177342","doi":"10.1038/sj.bjc.6602171","title":"Dietary induction of NQO1 increases the antitumour activity of mitomycin C in human colon tumours in vivo","year":2004,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CancerCare Manitoba; University of Manitoba","funders":"National Cancer Institute; Canadian Institutes of Health Research; American Institute for Cancer Research","keywords":"Dicoumarol; In vivo; Mitomycin C; Pharmacology; Toxicity; Ratón; NAD+ kinase; In vitro; Chemistry; Biology; Enzyme; Biochemistry; Medicine; Immunology; Internal medicine","score_opus":0.08621952986380309,"score_gpt":0.42144747229488816,"score_spread":0.33522794243108506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027177342","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994458,0.0042119003,0.000003793997,0.00037475108,0.00051520823,0.00014655634,0.000058205966,0.0000028619852,0.00022873019],"genre_scores_gemma":[0.9968555,0.0027739862,0.00002496702,0.00011749332,0.00018624225,0.000005461978,8.29824e-7,0.000009565208,0.000025984818],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998689,0.0003350528,0.00047952041,0.00011364947,0.00018711238,0.00019565405],"domain_scores_gemma":[0.9991027,0.000079993595,0.0005475625,0.000061072984,0.00014689937,0.000061744395],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006941249,0.00010608213,0.00036172144,0.00015412063,0.00007841206,0.000010353492,0.00022011415,0.000119509146,0.00019797328],"category_scores_gemma":[0.000050483006,0.00010033533,0.000114480754,0.00027842927,0.00026738344,0.00021156635,0.000040279076,0.00071803376,3.0222412e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069654285,0.0015788777,0.40064466,0.00009324487,0.00012331216,0.0004432106,0.00027822435,0.0019204821,0.5790187,0.00005121148,0.0007385956,0.014412955],"study_design_scores_gemma":[0.002626519,0.00018232051,0.7284435,0.00043873463,0.00006487798,0.00024670773,0.00014661539,0.0000133296635,0.26670137,0.0003163176,0.0007264788,0.00009322445],"about_ca_topic_score_codex":0.007802533,"about_ca_topic_score_gemma":0.010445626,"teacher_disagreement_score":0.32779884,"about_ca_system_score_codex":0.00014353986,"about_ca_system_score_gemma":0.00019969647,"threshold_uncertainty_score":0.99880457},"labels":[],"label_agreement":null},{"id":"W2031028099","doi":"10.3762/bjoc.9.158","title":"Thiourea-catalyzed Diels–Alder reaction of a naphthoquinone monoketal dienophile","year":2013,"lang":"en","type":"article","venue":"Beilstein Journal of Organic Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Tellabs (Canada)","funders":"","keywords":"Chemistry; Diels–Alder reaction; Naphthoquinone; Thiourea; Catalysis; Organic chemistry; Combinatorial chemistry; Photochemistry","score_opus":0.05702627673223892,"score_gpt":0.3555109031659617,"score_spread":0.29848462643372276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031028099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99459183,0.0010907054,0.000052960433,0.0005540266,0.00058767723,0.000121340185,0.000014600528,0.000016958988,0.0029698748],"genre_scores_gemma":[0.9979907,0.00029549515,0.00016166674,0.00009412115,0.00046365015,0.0000038944613,0.00000951416,0.000026345211,0.0009546132],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985296,0.00009103892,0.00066348456,0.00018202336,0.00024211213,0.00029172172],"domain_scores_gemma":[0.9982929,0.00012661766,0.00075935666,0.00019347385,0.00038077074,0.0002468629],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00038463724,0.00021459228,0.00041733732,0.00005665095,0.00010505909,0.00002116022,0.0003583765,0.0002805017,0.0066268425],"category_scores_gemma":[0.00011626186,0.00018522723,0.00021248733,0.0001938639,0.0001789509,0.00024929305,0.0000885428,0.0007359638,0.00005099123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015886618,0.0004815428,0.0039356938,0.000095843156,0.00031300023,0.00005046304,0.0001951669,0.0000021994697,0.9904903,0.000009416643,0.0022635383,0.0020039252],"study_design_scores_gemma":[0.0019981416,0.0001141782,0.006990991,0.000066461806,0.00019608722,0.0006529013,0.00044734753,0.000038365724,0.9837631,0.0002129918,0.00530688,0.00021256466],"about_ca_topic_score_codex":0.00000779425,"about_ca_topic_score_gemma":7.129877e-7,"teacher_disagreement_score":0.0067272554,"about_ca_system_score_codex":0.00008299588,"about_ca_system_score_gemma":0.0001259361,"threshold_uncertainty_score":0.99428123},"labels":[],"label_agreement":null},{"id":"W2032786541","doi":"10.1016/s0022-2836(03)00444-3","title":"Structural Insights into the Activation of P.vivax Plasmepsin","year":2003,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":55,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; Canada Research Chairs","keywords":"Biology; Computational biology","score_opus":0.07219434717894091,"score_gpt":0.4173164477245963,"score_spread":0.3451221005456554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2032786541","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99492216,0.0010557794,0.0012523704,0.000697154,0.00094865926,0.00007963125,0.0000015383068,0.000003231691,0.0010394527],"genre_scores_gemma":[0.9984875,0.00016020944,0.000583012,0.0006384515,0.00007993599,0.0000010944084,0.0000022255583,0.00000744238,0.00004013974],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998587,0.0007170208,0.00036435478,0.000095921285,0.00008573462,0.00014993873],"domain_scores_gemma":[0.999068,0.00013852493,0.00043993423,0.00009844044,0.00019064797,0.0000644589],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003650921,0.00011318503,0.00022160374,0.00009784797,0.00010721322,0.0000056534063,0.00022836402,0.0001798742,0.00016691553],"category_scores_gemma":[0.00016266647,0.00006920254,0.00013185953,0.00013727642,0.00025076352,0.000064633416,0.000029424156,0.0004525821,0.0000033998588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019619454,0.00006344835,0.004256299,0.000008584329,0.0002288545,0.000023766917,0.00042181337,0.0001341887,0.9711503,0.02048542,0.0003114127,0.002719713],"study_design_scores_gemma":[0.0009985749,0.00042489657,0.002684872,0.000011087471,0.00007247772,0.00014002236,0.00016467305,0.0000658543,0.9232973,0.013961483,0.058079313,0.000099437784],"about_ca_topic_score_codex":0.0000049420173,"about_ca_topic_score_gemma":0.000002299615,"teacher_disagreement_score":0.0577679,"about_ca_system_score_codex":0.00003123502,"about_ca_system_score_gemma":0.00008233781,"threshold_uncertainty_score":0.28219977},"labels":[],"label_agreement":null},{"id":"W2035613220","doi":"10.1007/s00280-001-0395-1","title":"The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase","year":2001,"lang":"en","type":"article","venue":"Cancer Chemotherapy and Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Tirapazamine; Quinone; Chemistry; Moiety; Benzoquinone; Enzyme; Stereochemistry; Mitomycin C; Cytotoxicity; Pharmacology; Biochemistry; Combinatorial chemistry; In vitro; Medicine","score_opus":0.05966073775841671,"score_gpt":0.40343111872770565,"score_spread":0.3437703809692889,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035613220","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994012,0.0022375283,0.000039670198,0.0016100438,0.0013228693,0.00042161174,0.000056363315,0.000015410635,0.00028452283],"genre_scores_gemma":[0.98625946,0.012376946,0.000004337386,0.0006443343,0.00030916743,0.0000830934,0.000017717926,0.000016007343,0.000288906],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99879736,0.00034901497,0.00024284708,0.0002774499,0.000105535866,0.00022779962],"domain_scores_gemma":[0.9991532,0.00036257214,0.00023941771,0.0000764851,0.00007248976,0.000095854215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035575073,0.00019688455,0.00026926448,0.000070653085,0.00023489674,0.0000072752323,0.00009213911,0.00017391425,0.0005512468],"category_scores_gemma":[0.000009256101,0.00014550514,0.00005844548,0.00017683672,0.0006879511,0.00008852671,0.000025306968,0.00030837048,0.000001274798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008073665,0.0002165411,0.014718908,0.000064812906,0.00049794087,0.0000016879878,0.00037956293,0.000046536952,0.89796776,0.00008697046,0.018749781,0.059195843],"study_design_scores_gemma":[0.004390244,0.0009276569,0.009764044,0.000017637263,0.00013612007,0.000016608097,0.00009232218,0.00031457184,0.93520784,0.000105754785,0.04888299,0.00014421913],"about_ca_topic_score_codex":0.000029641935,"about_ca_topic_score_gemma":0.0000011054054,"teacher_disagreement_score":0.059051625,"about_ca_system_score_codex":0.000051423867,"about_ca_system_score_gemma":0.000028195183,"threshold_uncertainty_score":0.6035766},"labels":[],"label_agreement":null},{"id":"W2037166773","doi":"10.1139/y11-058","title":"Protective effects of diosmetin extracted from <i>Galium verum</i> L. on the thymus of U14-bearing mice","year":2011,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Fas ligand; Apoptosis; CD8; Biology; Tumor necrosis factor alpha; Flow cytometry; Molecular biology; T lymphocyte; Endocrinology; Immune system; Immunology; Programmed cell death; Biochemistry","score_opus":0.07957957873381126,"score_gpt":0.33370336592353195,"score_spread":0.2541237871897207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037166773","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99462795,0.0013993673,0.000025088428,0.00035252198,0.00229972,0.0003483762,0.000085754466,0.0000048830584,0.000856349],"genre_scores_gemma":[0.9979365,0.000210069,0.000066146706,0.0014457561,0.0002812664,0.0000132217865,0.0000034159352,0.000016184076,0.000027436832],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977515,0.001094852,0.00047586302,0.00021539668,0.00007616778,0.00038624724],"domain_scores_gemma":[0.9974807,0.0011913503,0.0006442146,0.0001170935,0.00023702481,0.00032960915],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004883083,0.00022292329,0.0005291596,0.00020004917,0.00020828171,0.000003443465,0.0004174829,0.000306105,0.002026911],"category_scores_gemma":[0.00010783984,0.0001648656,0.00015254095,0.00016906697,0.00095817755,0.000079668025,0.000043171338,0.0010789377,0.000007835108],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010935514,0.00022728457,0.0043791113,0.00010632656,0.00079507136,0.000112113274,0.001746849,0.000009285196,0.98778707,0.00060193375,0.0015481192,0.0015932971],"study_design_scores_gemma":[0.0016447358,0.0009147629,0.07318147,0.000054707823,0.0003527827,0.00003321414,0.000138168,0.000035277924,0.9172125,0.0024687022,0.0038123855,0.00015129226],"about_ca_topic_score_codex":0.001444973,"about_ca_topic_score_gemma":0.00034394322,"teacher_disagreement_score":0.07057456,"about_ca_system_score_codex":0.000041939173,"about_ca_system_score_gemma":0.000332954,"threshold_uncertainty_score":0.9988854},"labels":[],"label_agreement":null},{"id":"W2037407093","doi":"10.3390/molecules190914902","title":"1,4-Naphthoquinones: From Oxidative Damage to Cellular and Inter-Cellular Signaling","year":2014,"lang":"en","type":"review","venue":"Molecules","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":221,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Juglone; Plumbagin; Oxidative stress; Menadione; Cell biology; Lawsone; Oxidative phosphorylation; Reactive oxygen species; Signal transduction; Chemistry; Pro-oxidant; Redox; Biochemistry; Cell signaling; Biology","score_opus":0.1447821862825263,"score_gpt":0.4342533037244728,"score_spread":0.28947111744194653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037407093","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009535293,0.979671,0.00711418,0.000072248586,0.0010065871,0.0008597337,0.0004317863,0.00008821247,0.0012209704],"genre_scores_gemma":[0.008324158,0.9870945,0.0011558764,0.0010377339,0.00068589905,0.00013232192,0.0005942236,0.0001385238,0.00083675707],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99662936,0.0011457704,0.00063615286,0.000892443,0.00017129509,0.00052501017],"domain_scores_gemma":[0.9982603,0.00052348146,0.00034475076,0.00038608108,0.00007634086,0.00040901834],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00044717893,0.0007242866,0.0016235022,0.00025038313,0.000254207,0.00010292356,0.00058801426,0.0006620143,0.00076103583],"category_scores_gemma":[0.00007239922,0.00063150155,0.000387063,0.00023916394,0.00023548804,0.00006480535,0.00047206154,0.0010273794,0.0005051361],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008934106,0.0004385951,0.00009326109,0.0062045357,0.0019685284,0.00083537615,0.0007498937,0.000007567992,0.047375366,0.00077545084,0.005856665,0.9356054],"study_design_scores_gemma":[0.00034723344,0.00011566547,0.0000034436187,0.0022600295,0.0011195804,0.0000072036423,0.00006031432,0.000074186275,0.008510981,0.00013539963,0.98667735,0.0006885902],"about_ca_topic_score_codex":0.000037414142,"about_ca_topic_score_gemma":0.0000061360465,"teacher_disagreement_score":0.9808207,"about_ca_system_score_codex":0.00007156177,"about_ca_system_score_gemma":0.000071681134,"threshold_uncertainty_score":0.99961364},"labels":[],"label_agreement":null},{"id":"W2038529531","doi":"10.1139/v10-084","title":"Naphthalene derivatives from Diospyros wallichii","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Diospyros; Naphthalene; Coumarin; Antifungal; Terpene; Stereochemistry; Hydroxymethyl; Organic chemistry; Botany; Microbiology","score_opus":0.06407282299434026,"score_gpt":0.3643517656291144,"score_spread":0.30027894263477417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038529531","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867915,0.0005406103,0.000014438689,0.0009297266,0.0013460016,0.00003340295,0.0001210822,0.000006113594,0.010217109],"genre_scores_gemma":[0.9973882,0.00003319831,0.00020090188,0.00058943836,0.00090482336,0.0000012081972,0.000011667246,0.000014581286,0.0008559753],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991697,0.00003799479,0.00027802083,0.00012626394,0.000092140195,0.00029587178],"domain_scores_gemma":[0.9985249,0.000098257624,0.0002134597,0.00012534772,0.00015661429,0.00088143564],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00019983658,0.00014195958,0.00020026953,0.000042144096,0.00018119265,0.000034495646,0.00038959706,0.00024644707,0.008649258],"category_scores_gemma":[0.00013034829,0.00013217071,0.00011622135,0.0000823394,0.00027857296,0.00010172114,0.00001571104,0.0011448856,0.000023341896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000344447,0.000043048032,0.07539118,0.000013669107,0.00016158937,0.00041433139,0.00026430885,0.000003548684,0.9137593,0.000025829671,0.0077577764,0.0021309555],"study_design_scores_gemma":[0.00078384636,0.000022746292,0.028637638,0.000022289902,0.000047214573,0.00024271339,0.00015338209,0.000021333655,0.6847848,0.0005662087,0.28452393,0.00019385718],"about_ca_topic_score_codex":0.00032510792,"about_ca_topic_score_gemma":0.0016129494,"teacher_disagreement_score":0.27676615,"about_ca_system_score_codex":0.000045190784,"about_ca_system_score_gemma":0.00063047645,"threshold_uncertainty_score":0.992257},"labels":[],"label_agreement":null},{"id":"W2038906803","doi":"10.1002/chin.200727170","title":"Total Synthesis of (.+‐.)‐Herbindole A (I), (.+‐.)‐Herbindole B (II), and (.+‐.)‐cis‐Trikentrin A (III).","year":2007,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Combinatorial chemistry; Stereochemistry","score_opus":0.05892505516835763,"score_gpt":0.3736362880231092,"score_spread":0.3147112328547516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038906803","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8526424,0.00077323744,0.000008116434,0.00010714671,0.00032905198,0.00031607394,0.000030073683,0.000044407265,0.1457495],"genre_scores_gemma":[0.99462926,0.00021828573,0.00008694982,0.0002483885,0.00012742385,0.00002352883,0.00000849461,0.000023215607,0.0046344763],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981992,0.0000061998408,0.00063046353,0.0003166982,0.0002056139,0.0006417767],"domain_scores_gemma":[0.99883,0.00039403705,0.00022815602,0.0002122443,0.000080203965,0.00025533658],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001022701,0.00028124204,0.00046055592,0.00022657667,0.00016999875,0.000017803979,0.00024425538,0.00035572427,0.0008940437],"category_scores_gemma":[0.00009640134,0.00027139418,0.0001269827,0.00035909304,0.00032977198,0.0001994476,0.00022468193,0.00047627144,0.000029426126],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037218402,0.0018640026,0.062531814,0.0006516227,0.00042211395,0.00030189235,0.0044366443,0.0000073976553,0.1699795,0.0022403307,0.0072941366,0.7465487],"study_design_scores_gemma":[0.0033112934,0.00017226754,0.033117805,0.00010902329,0.00008841102,0.000117174895,0.00085092837,0.000113994065,0.92017156,0.00014037981,0.041354995,0.00045214355],"about_ca_topic_score_codex":0.00008447847,"about_ca_topic_score_gemma":0.000045978337,"teacher_disagreement_score":0.7501921,"about_ca_system_score_codex":0.00010846387,"about_ca_system_score_gemma":0.00007200492,"threshold_uncertainty_score":0.99997383},"labels":[],"label_agreement":null},{"id":"W2039607641","doi":"10.1016/j.bmc.2005.04.032","title":"1,12-Substituted tetracyclines as antioxidant agents","year":2005,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Steacie Institute for Molecular Sciences; Biotechnology Research Institute; National Research Council Canada","funders":"","keywords":"Chemistry; Tetracycline; Minocycline; Antioxidant; ABTS; DPPH; Hydrazine (antidepressant); Superoxide; Oxidative stress; Stereochemistry; Combinatorial chemistry; Antibiotics; Biochemistry; Enzyme","score_opus":0.11368880976965857,"score_gpt":0.4257164382617278,"score_spread":0.3120276284920692,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039607641","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97216606,0.0011563447,0.000043207114,0.0028633655,0.0009881519,0.00016891652,0.00003563155,0.00017921701,0.02239908],"genre_scores_gemma":[0.98916274,0.00057359587,0.00013849912,0.0025854993,0.0021591196,0.00001122017,0.000052922776,0.000034563545,0.0052818274],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981322,0.00007065448,0.00043953428,0.00047621774,0.00032585778,0.0005554951],"domain_scores_gemma":[0.9989068,0.000097600634,0.0001761195,0.00027958097,0.00010118427,0.0004387002],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00034799497,0.00033797004,0.00033205692,0.00004527224,0.00027760095,0.000023957906,0.00045376792,0.000390189,0.013062554],"category_scores_gemma":[0.00017697168,0.00030114816,0.0001268758,0.00017598116,0.00035658263,0.00012082811,0.00010913595,0.0007651131,0.00078003237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015431165,0.0005154804,0.009877797,0.00008411115,0.00017211755,0.0001987745,0.00015962686,0.0000032700798,0.96193814,0.00004156818,0.018532416,0.008322375],"study_design_scores_gemma":[0.0016275363,0.000036126086,0.011202551,0.000046840138,0.00014781236,0.00027522838,0.00015151734,0.00022066913,0.6011262,0.00003871502,0.384811,0.00031575616],"about_ca_topic_score_codex":0.000019571698,"about_ca_topic_score_gemma":0.0000061956252,"teacher_disagreement_score":0.36627862,"about_ca_system_score_codex":0.00012993286,"about_ca_system_score_gemma":0.00015685527,"threshold_uncertainty_score":0.999998},"labels":[],"label_agreement":null},{"id":"W2040084570","doi":"10.1007/s11224-011-9735-x","title":"Theoretical study of substituent and solvent effects on the thermodynamics for cis/trans isomerization and intramolecular rearrangements of 2,2′-diphenoquinones","year":2011,"lang":"en","type":"article","venue":"Structural Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Okanagan College","funders":"Western Canada Research Grid","keywords":"Chemistry; Isomerization; Substituent; Acetonitrile; Solvent; Intramolecular force; Gibbs free energy; Solvent effects; Polar effect; Medicinal chemistry; Computational chemistry; Stereochemistry; Organic chemistry; Thermodynamics; Catalysis","score_opus":0.059688318447248936,"score_gpt":0.3542786284778226,"score_spread":0.2945903100305737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040084570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985412,0.000106233114,0.000102836144,0.00004084173,0.000105633844,0.0004839606,0.000033018787,0.0000069688913,0.00057934737],"genre_scores_gemma":[0.99979,0.00003789847,0.000053128937,0.00004734088,0.000026739677,0.000021052889,0.000008904422,0.000008939744,0.000005967609],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993986,0.00006780498,0.00016335702,0.00016400697,0.000081663624,0.00012456042],"domain_scores_gemma":[0.9995942,0.00011665218,0.00009321321,0.000103696795,0.0000462628,0.000045968354],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011764484,0.00012336852,0.00016228904,0.0000120915265,0.00009105124,0.0000046051405,0.00010402497,0.0000796392,0.00013075823],"category_scores_gemma":[0.000022702716,0.00008293297,0.000034689336,0.00004119441,0.0003475151,0.000018909739,0.000036359066,0.00013079007,7.423642e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008464175,0.00021356606,0.012087589,0.00037115908,0.00029222202,0.0000040040895,0.002361229,0.000004257,0.9724351,0.008384273,0.0000054228344,0.0029947234],"study_design_scores_gemma":[0.0019323737,0.00054408377,0.040239576,0.00003386046,0.0002480318,0.000005895898,0.0008906806,0.0014212504,0.94805676,0.0064652343,0.0000139902195,0.00014826086],"about_ca_topic_score_codex":0.000004253578,"about_ca_topic_score_gemma":9.963591e-7,"teacher_disagreement_score":0.028151989,"about_ca_system_score_codex":0.000007780191,"about_ca_system_score_gemma":0.0000071077757,"threshold_uncertainty_score":0.33819082},"labels":[],"label_agreement":null},{"id":"W2040643895","doi":"10.1039/c2ob25492a","title":"The first isocyanide of plant origin expands functional group diversity in cruciferous phytoalexins: synthesis, structure and bioactivity of isocyalexin A","year":2012,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Isocyanide; Chemistry; Phytoalexin; Chemical structure; Botany; Stereochemistry; Organic chemistry; Biology; Biochemistry","score_opus":0.05808904188040707,"score_gpt":0.320236584733921,"score_spread":0.26214754285351394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040643895","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960918,0.0021755446,0.00072959496,0.00015550596,0.00023576635,0.00012899099,0.00029142055,0.000014944031,0.00017643235],"genre_scores_gemma":[0.99931407,0.00040185588,0.00003308589,0.00008499484,0.000091081456,0.0000059176728,0.000022970951,0.000014460625,0.000031538584],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988974,0.00009788387,0.00025646624,0.00023849642,0.00017028718,0.0003395093],"domain_scores_gemma":[0.9992363,0.00020575126,0.00020507691,0.00019624611,0.00004038851,0.00011622536],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003217079,0.00020455022,0.0002714718,0.0000338353,0.00029085675,0.000009120029,0.00023016718,0.00025956324,0.00040275618],"category_scores_gemma":[0.00006563992,0.00016765842,0.00008528572,0.00020613289,0.0004339339,0.00008301477,0.00030834763,0.00034198974,0.0000019849454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023820471,0.0003029153,0.1586426,0.00015089185,0.00014863092,0.000009797595,0.00018276554,2.537468e-7,0.83970594,0.00007602019,0.00018951032,0.0003524536],"study_design_scores_gemma":[0.0007614222,0.000025466012,0.061241858,0.00003724115,0.00009479572,0.0000495122,0.00018439893,0.0000355801,0.93416613,0.00008282758,0.0031416176,0.00017915825],"about_ca_topic_score_codex":0.000043332777,"about_ca_topic_score_gemma":0.00003603884,"teacher_disagreement_score":0.09740074,"about_ca_system_score_codex":0.000077998295,"about_ca_system_score_gemma":0.00004137996,"threshold_uncertainty_score":0.6836912},"labels":[],"label_agreement":null},{"id":"W2049574160","doi":"10.1074/jbc.m113.457002","title":"Chloroquine Binding Reveals Flavin Redox Switch Function of Quinone Reductase 2","year":2013,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Saskatchewan; Canadian Light Source","keywords":"Quinone; Chemistry; Cofactor; Stereochemistry; Flavin adenine dinucleotide; Reductase; Redox; Enzyme; Biochemistry","score_opus":0.11139768870720632,"score_gpt":0.3869014440403148,"score_spread":0.27550375533310845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049574160","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962175,0.0007163563,0.000038254715,0.00054942275,0.0005425168,0.00010089755,0.000024059957,0.000014453635,0.0017965597],"genre_scores_gemma":[0.99780786,0.0004003378,0.00023878245,0.00023652833,0.00061912433,0.000004555194,0.0000162707,0.000008526446,0.0006680065],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99856883,0.00012888644,0.0006932648,0.00017793603,0.00015243441,0.00027866996],"domain_scores_gemma":[0.99847597,0.0001655346,0.0007180662,0.00011845491,0.00029607143,0.0002258941],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006436869,0.00017764853,0.0004202592,0.00004564462,0.00009188348,0.000014655866,0.00027592777,0.00038373563,0.004936102],"category_scores_gemma":[0.00020977884,0.00012356341,0.00021055351,0.00016853846,0.0002415689,0.00011712748,0.00007792703,0.00072914077,0.000040389445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037378987,0.0003668998,0.014321744,0.000055991568,0.00014404322,0.000032423486,0.000021693162,0.0000048564993,0.9732149,0.000014747182,0.0089838635,0.0024650432],"study_design_scores_gemma":[0.0011644897,0.00046478724,0.015595868,0.000062315965,0.00009354084,0.00020412037,0.00019643226,0.000024456136,0.97310454,0.00061710086,0.008290186,0.00018215642],"about_ca_topic_score_codex":0.0000033178233,"about_ca_topic_score_gemma":7.074626e-8,"teacher_disagreement_score":0.0048957127,"about_ca_system_score_codex":0.0000563358,"about_ca_system_score_gemma":0.00004191848,"threshold_uncertainty_score":0.9959735},"labels":[],"label_agreement":null},{"id":"W2050395172","doi":"10.1016/j.bmcl.2009.07.007","title":"Benzo[c][2,7]naphthyridines as inhibitors of PDK-1","year":2009,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Chemistry; Stereochemistry; Crystal structure; Potency; Crystallography; In vitro; Biochemistry","score_opus":0.05960049505898765,"score_gpt":0.3892484320361612,"score_spread":0.32964793697717354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050395172","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9781757,0.0007366224,0.000021509088,0.014960081,0.00067125895,0.00013196345,0.000021251262,0.00007416684,0.0052074557],"genre_scores_gemma":[0.9914006,0.00012896572,0.000047904636,0.0070561185,0.0009780462,0.000003516809,0.000032361902,0.000018312161,0.00033416148],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99846953,0.000067737834,0.00037343166,0.00036563922,0.00029746213,0.00042621043],"domain_scores_gemma":[0.99910957,0.000088305664,0.00022218241,0.0002343855,0.000078414785,0.0002671483],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00029594984,0.00028509085,0.00035258394,0.000051920193,0.00013303618,0.000010246305,0.00037186863,0.0002449418,0.002356901],"category_scores_gemma":[0.000102700855,0.00025637314,0.00014099163,0.00027498647,0.0003549907,0.00007242466,0.00005037208,0.0005414806,0.00007078213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013901464,0.00020109754,0.0032073106,0.00006695013,0.000087024346,0.00011141063,0.00014025843,0.0000012872239,0.9604796,0.000035007954,0.032591153,0.0029398554],"study_design_scores_gemma":[0.0011639884,0.0000959165,0.0050821193,0.00006017552,0.00012515188,0.00013006407,0.00015673357,0.000014837284,0.9578874,0.000060934588,0.03496188,0.00026081162],"about_ca_topic_score_codex":0.000011602635,"about_ca_topic_score_gemma":4.1258974e-7,"teacher_disagreement_score":0.013224922,"about_ca_system_score_codex":0.000071983784,"about_ca_system_score_gemma":0.000075836644,"threshold_uncertainty_score":0.99998885},"labels":[],"label_agreement":null},{"id":"W2050433141","doi":"10.1158/1078-0432.ccr-04-1751","title":"Preclinical Evaluation of the Pharmacodynamic Properties of 2,5-Diaziridinyl-3-Hydroxymethyl-6-Methyl-1,4-Benzoquinone","year":2005,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Christie (Canada)","funders":"Department of Health and Social Care; National Institute for Health and Care Research","keywords":"In vivo; Comet assay; DNA damage; Pharmacology; Cytotoxicity; Cisplatin; Mitomycin C; DNA; Topoisomerase; In vitro; Chemistry; Biochemistry; Biology; Chemotherapy","score_opus":0.7834550027564526,"score_gpt":0.6806333684334336,"score_spread":0.10282163432301905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050433141","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9828763,0.0077962955,0.0000068651543,0.0038954138,0.0015336786,0.0011305393,0.000080299666,0.000020369418,0.0026602133],"genre_scores_gemma":[0.994806,0.00276096,0.000058536967,0.00045811935,0.00086295337,0.0001675188,0.0000035392222,0.000027679007,0.00085471437],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9894088,0.006724387,0.0013206713,0.00052179553,0.0014468012,0.0005775297],"domain_scores_gemma":[0.995568,0.0015856058,0.00042693786,0.0005180265,0.0016697138,0.00023173286],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.020435091,0.0001986598,0.00053670513,0.000137689,0.0002787966,0.000014237192,0.0010110514,0.00041506,0.002376436],"category_scores_gemma":[0.0020821954,0.00013440696,0.00040127404,0.00064329966,0.0024150724,0.00014147552,0.0005051706,0.0022018827,0.000055853016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024002923,0.0036872611,0.11519733,0.00030713566,0.00081027276,0.0000021598858,0.0005299769,0.0024052423,0.48153523,0.00042286149,0.011317762,0.38138446],"study_design_scores_gemma":[0.008088458,0.0006089941,0.08488297,0.00036173634,0.0007122849,0.000004004666,0.00020176463,0.08802873,0.73818254,0.00073936407,0.07778257,0.00040656436],"about_ca_topic_score_codex":0.00012260034,"about_ca_topic_score_gemma":0.00014018438,"teacher_disagreement_score":0.3809779,"about_ca_system_score_codex":0.00019517766,"about_ca_system_score_gemma":0.0010328448,"threshold_uncertainty_score":0.9985355},"labels":[],"label_agreement":null},{"id":"W2052224849","doi":"10.1002/chin.200433116","title":"The Diels—Alder Reactions of Quinone Imine Ketals.","year":2004,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Quinone; Imine; Diels–Alder reaction; Organic chemistry; Medicinal chemistry; Catalysis","score_opus":0.10513937401561436,"score_gpt":0.41147647388532427,"score_spread":0.3063370998697099,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052224849","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.38945433,0.00090096507,0.000013128371,0.0023043326,0.0012556349,0.00026961393,0.00003839028,0.000069404094,0.6056942],"genre_scores_gemma":[0.9868001,0.0005724511,0.00003153832,0.00035732347,0.00013952328,0.000018349698,0.000014332067,0.000009335389,0.012057098],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992663,0.0000018915283,0.00026930275,0.00010901812,0.000100979036,0.0002524569],"domain_scores_gemma":[0.9993771,0.0001286176,0.00013944998,0.00017583351,0.00008588053,0.000093122326],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022973192,0.00011903669,0.00013574107,0.000028639359,0.00028856331,0.000012501304,0.00021235672,0.00012493921,0.0003916664],"category_scores_gemma":[0.000052201132,0.000083021885,0.00009746102,0.00013449657,0.00031981347,0.000098770885,0.00006838988,0.00030078352,0.000074630865],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008857294,0.0017365051,0.0041747675,0.0003423371,0.0011893439,0.000055016244,0.0030194519,0.00007162927,0.3831369,0.04458135,0.07828799,0.48251897],"study_design_scores_gemma":[0.00081309705,0.0000450137,0.0018727938,0.000013318538,0.00004322449,0.000020533773,0.00022192062,0.000011490445,0.5266355,0.000640747,0.46958154,0.00010079789],"about_ca_topic_score_codex":0.000022929133,"about_ca_topic_score_gemma":0.000014039612,"teacher_disagreement_score":0.5973457,"about_ca_system_score_codex":0.000053382108,"about_ca_system_score_gemma":0.00005698666,"threshold_uncertainty_score":0.42884725},"labels":[],"label_agreement":null},{"id":"W2058737189","doi":"10.1007/s00280-007-0417-8","title":"Role of NADPH cytochrome P450 reductase in activation of RH1","year":2007,"lang":"en","type":"article","venue":"Cancer Chemotherapy and Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Cytochrome P450; Reductase; Chemistry; Cytochrome P450 reductase; Pharmacology; Biochemistry; Cell biology; Enzyme; Biology; Cytochrome c; Apoptosis; Coenzyme Q – cytochrome c reductase","score_opus":0.06604078805472001,"score_gpt":0.44078947350474135,"score_spread":0.3747486854500213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058737189","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941568,0.0027203686,0.00003504486,0.00043683097,0.00032693657,0.00033872473,0.000051208757,0.00001635582,0.0019177741],"genre_scores_gemma":[0.9954605,0.0026043283,0.00009930862,0.001435754,0.00023233012,0.000027240749,0.0000101040205,0.000018876586,0.00011155283],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99873334,0.00013841157,0.00042436863,0.00026695314,0.00009237629,0.0003445656],"domain_scores_gemma":[0.99922734,0.00020691082,0.00026803193,0.000086749984,0.00009289809,0.0001180489],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00052197394,0.00018327887,0.00036598157,0.00019392,0.00006214065,0.0000027225485,0.00016308422,0.0002533097,0.002118866],"category_scores_gemma":[0.000008119573,0.0001830109,0.000064252876,0.0002996939,0.00038847007,0.00009689398,0.000035593283,0.00037714458,0.0000017606861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017707825,0.00041835068,0.017839877,0.00009022531,0.0001642444,0.0000053712897,0.0012765542,0.000030235682,0.9332608,0.00028983472,0.0005604338,0.044293296],"study_design_scores_gemma":[0.003127755,0.00014537253,0.042495936,0.000023825643,0.000046896093,0.0000066238144,0.00030109996,0.00023228455,0.92151207,0.0005130448,0.031436566,0.00015851737],"about_ca_topic_score_codex":0.00014178517,"about_ca_topic_score_gemma":0.000026408263,"teacher_disagreement_score":0.04413478,"about_ca_system_score_codex":0.000074644624,"about_ca_system_score_gemma":0.00009182289,"threshold_uncertainty_score":0.9987933},"labels":[],"label_agreement":null},{"id":"W2061288567","doi":"10.1080/10715760600833077","title":"The reductive activation of the antitumor drug RH1 to its semiquinone free radical by NADPH cytochrome P450 reductase and by HCT116 human colon cancer cells","year":2006,"lang":"en","type":"article","venue":"Free Radical Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Semiquinone; Chemistry; Reductase; Radical; Oxidoreductase; Spin trapping; Benzoquinone; Biochemistry; Enzyme; Stereochemistry; Photochemistry; Quinone","score_opus":0.10601419305230342,"score_gpt":0.46092209359913616,"score_spread":0.35490790054683274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061288567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97600156,0.0028568513,0.000013770908,0.016917093,0.0003324582,0.0012041698,0.0010198306,0.000028950028,0.0016253255],"genre_scores_gemma":[0.9925656,0.00063719146,0.00003755013,0.00035845063,0.00048350057,0.00017038113,0.000037872265,0.00003589735,0.0056735845],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9955924,0.0015313718,0.00045673415,0.0005876011,0.000936253,0.00089561334],"domain_scores_gemma":[0.9974967,0.0010500648,0.00016296761,0.0005733868,0.00031240835,0.00040447497],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0019968606,0.00026328187,0.0003392369,0.00011670142,0.0016146718,0.000082874816,0.0013649879,0.00029073728,0.00046724465],"category_scores_gemma":[0.0005540983,0.00017878604,0.00010238717,0.00070547283,0.0026934315,0.00016196798,0.00073076924,0.0017657507,0.000017946339],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002737878,0.0003303908,0.0002546762,0.000026794498,0.00005271613,0.0000063007474,0.00012361983,0.0000043008977,0.5689215,0.0011436957,0.42825207,0.00061012286],"study_design_scores_gemma":[0.0014554072,0.00019894072,0.0034012464,0.000064500025,0.000035046858,0.000007251311,0.00013445319,0.00013425147,0.7724194,0.0017933281,0.22016203,0.00019418144],"about_ca_topic_score_codex":0.0014121394,"about_ca_topic_score_gemma":0.00017150384,"teacher_disagreement_score":0.20809005,"about_ca_system_score_codex":0.00031006595,"about_ca_system_score_gemma":0.00027870547,"threshold_uncertainty_score":0.9996851},"labels":[],"label_agreement":null},{"id":"W2062642760","doi":"10.1039/c4ra11940a","title":"Synthesis of novel dispiropyrrolothiazoles by three-component 1,3-dipolar cycloaddition and evaluation of their antimycobacterial activity","year":2014,"lang":"en","type":"article","venue":"RSC Advances","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Compute Canada","keywords":"Antimycobacterial; Component (thermodynamics); 1,3-Dipolar cycloaddition; Cycloaddition; Chemistry; Combinatorial chemistry; Stereochemistry; Organic chemistry; Mycobacterium tuberculosis; Medicine; Tuberculosis; Physics","score_opus":0.08067299642632356,"score_gpt":0.385601262345021,"score_spread":0.3049282659186975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062642760","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956776,0.001077071,0.0014132415,0.00011339804,0.00047264004,0.00022975219,0.00050675933,0.000018067258,0.00049149094],"genre_scores_gemma":[0.99901414,0.0005692486,0.00020885836,0.000037223,0.00010551842,0.000024155706,0.000026530435,0.000010604776,0.0000037143882],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988581,0.00030669698,0.00023185588,0.00022615168,0.00020946343,0.0001677341],"domain_scores_gemma":[0.99896187,0.00041422655,0.00031630314,0.00012114546,0.00012529817,0.000061187384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00080258434,0.00015788674,0.00030158638,0.000053207415,0.00011673823,0.0000074103127,0.00011908848,0.00012020514,0.00016258864],"category_scores_gemma":[0.000094228875,0.00013152101,0.000063036314,0.00007322028,0.00030874368,0.00023270298,0.000048060585,0.00014273902,0.0000017130558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029619015,0.00053000276,0.012894725,0.000084996966,0.00008583361,1.0177697e-7,0.000058921265,0.00007104078,0.84906495,0.0002173885,0.00007678576,0.13661908],"study_design_scores_gemma":[0.0014041406,0.00012952849,0.09407027,0.000057121648,0.00021020675,0.0000026183586,0.00003087583,0.015231867,0.87803113,0.00050097005,0.010156988,0.00017425603],"about_ca_topic_score_codex":0.00002067743,"about_ca_topic_score_gemma":0.000022203447,"teacher_disagreement_score":0.13644482,"about_ca_system_score_codex":0.000021669426,"about_ca_system_score_gemma":0.000020363139,"threshold_uncertainty_score":0.53632706},"labels":[],"label_agreement":null},{"id":"W2063536777","doi":"10.1254/jphs.92.203","title":"The Epoxy Group of Pramanicin Is Required for the Optimal Endothelium-Dependent Relaxation of Rat Aorta","year":2003,"lang":"en","type":"article","venue":"Journal of Pharmacological Sciences","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"McMaster University","keywords":"Epoxy; Aorta; Endothelium; Group (periodic table); Relaxation (psychology); Chemistry; Cardiology; Internal medicine; Medicine; Organic chemistry","score_opus":0.19290743660890639,"score_gpt":0.458371439725134,"score_spread":0.26546400311622764,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063536777","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9859318,0.0037922342,0.0014564977,0.0037254451,0.003302792,0.00058437313,0.000025677698,0.0000070613355,0.0011741054],"genre_scores_gemma":[0.99590826,0.0019855818,0.0009295174,0.0007201682,0.0001514177,0.000013620086,3.1403607e-7,0.0000051657653,0.0002859464],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99765956,0.0006202971,0.00077157014,0.00017663045,0.00044082617,0.00033113698],"domain_scores_gemma":[0.9958052,0.002415589,0.0012778642,0.00008154877,0.00031080458,0.000108976594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0052725635,0.00014520348,0.0002916203,0.000059032165,0.00069033774,0.00003484295,0.00077757094,0.00011706963,0.0005855809],"category_scores_gemma":[0.0004596112,0.000066721776,0.00025408913,0.00028849856,0.001200247,0.00017933373,0.00006227384,0.00041721927,0.00000286561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011858316,0.0009322096,0.009911668,0.000028299763,0.0005444714,0.00001659977,0.00046953486,0.0013454031,0.9539996,0.012092479,0.012507966,0.006965966],"study_design_scores_gemma":[0.003916984,0.0029244125,0.003886454,0.000030281553,0.00082005316,0.00012635153,0.0017114806,0.004310724,0.84070086,0.002888578,0.13845526,0.00022856295],"about_ca_topic_score_codex":0.0000042726824,"about_ca_topic_score_gemma":0.0000027479712,"teacher_disagreement_score":0.12594728,"about_ca_system_score_codex":0.00004125708,"about_ca_system_score_gemma":0.00013731219,"threshold_uncertainty_score":0.64117},"labels":[],"label_agreement":null},{"id":"W2066316435","doi":"10.1007/s00044-011-9788-9","title":"Cobalt mediated ring contraction reaction of lapachol and initial antibacterial evaluation of naphthoquinones derived from lapachol","year":2011,"lang":"en","type":"article","venue":"Medicinal Chemistry Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick","funders":"","keywords":"Chemistry; Contraction (grammar); Ring (chemistry); Pharmacology; Stereochemistry; Combinatorial chemistry; Organic chemistry; Internal medicine; Biology; Medicine","score_opus":0.46150446755058894,"score_gpt":0.526519126750625,"score_spread":0.06501465920003602,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066316435","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909995,0.0003755711,0.000010076446,0.00006741575,0.00037297717,0.00027523216,0.00009866998,0.000015373636,0.0077851675],"genre_scores_gemma":[0.9991647,0.00025199004,0.000030527895,0.000017088687,0.00035329885,0.000020652566,0.00012040628,0.00001139767,0.000029921775],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99768716,0.0007019932,0.00036602834,0.000272972,0.00069750065,0.00027433995],"domain_scores_gemma":[0.99821806,0.00043954517,0.0002176904,0.00014463092,0.00081891794,0.00016118365],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0029810593,0.00013140206,0.0002814194,0.000084750354,0.0001362049,0.0000071744535,0.00014796437,0.00027942393,0.0015768615],"category_scores_gemma":[0.0006998254,0.0001229611,0.000041563133,0.00018348367,0.000680628,0.00013124169,0.000067819,0.0006995632,0.000005465163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001804092,0.00031549006,0.0140226185,0.0001117804,0.00014192997,0.000014067036,0.0007503978,3.4025348e-7,0.97627056,0.000007202644,0.00007445545,0.0064870575],"study_design_scores_gemma":[0.0030570324,0.00014883539,0.08493491,0.00009165888,0.00015357276,0.000017706787,0.0008326963,0.00061011617,0.90956926,0.00013319172,0.00035731198,0.00009367906],"about_ca_topic_score_codex":0.00047964495,"about_ca_topic_score_gemma":0.000014773424,"teacher_disagreement_score":0.070912294,"about_ca_system_score_codex":0.00007276413,"about_ca_system_score_gemma":0.00015662744,"threshold_uncertainty_score":0.9993358},"labels":[],"label_agreement":null},{"id":"W2070090424","doi":"10.1158/0008-5472.can-08-4754","title":"Peroxisome Proliferator-Activated Receptor-γ Contributes to the Inhibitory Effects of Embelin on Colon Carcinogenesis","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Immunovaccine (Canada)","funders":"","keywords":"XIAP; Peroxisome proliferator-activated receptor; Chemistry; Apoptosis; Carcinogenesis; Cancer research; Receptor; Endocrinology; Internal medicine; Colorectal cancer; Cancer; Biology; Medicine; Biochemistry; Programmed cell death; Caspase","score_opus":0.17425735658433236,"score_gpt":0.5030674927568697,"score_spread":0.3288101361725373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070090424","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868673,0.0027164214,0.000005995294,0.0074701207,0.0009530545,0.0013230841,0.000067007626,0.000034068893,0.0005629344],"genre_scores_gemma":[0.9953025,0.00061078026,0.0000068292647,0.002687064,0.0004367673,0.00029604568,0.000007692479,0.000018881294,0.000633437],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99727225,0.001108862,0.00024588022,0.0003654292,0.00039748597,0.00061009685],"domain_scores_gemma":[0.99820167,0.00075197883,0.00006768174,0.0002704284,0.00049589516,0.00021236786],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011326919,0.00018223868,0.00029073277,0.00021695642,0.00048323118,0.000029840108,0.00044272607,0.00021460647,0.0002553979],"category_scores_gemma":[0.00027842127,0.00013125206,0.000083097715,0.000760589,0.00027073445,0.000050795144,0.00009403371,0.0008979936,0.00011508292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014680595,0.00040476193,0.0056688725,0.000070129165,0.000115084855,0.000013133027,0.0003566616,0.00006200517,0.93104655,0.0006066284,0.049895205,0.010292895],"study_design_scores_gemma":[0.0010377472,0.0007948503,0.015466291,0.00011143146,0.000022558761,6.763129e-7,0.00006970781,0.000023054612,0.87705654,0.00009071965,0.1052046,0.000121820165],"about_ca_topic_score_codex":0.000060022714,"about_ca_topic_score_gemma":0.000020893034,"teacher_disagreement_score":0.055309393,"about_ca_system_score_codex":0.00029936526,"about_ca_system_score_gemma":0.0002477611,"threshold_uncertainty_score":0.5352304},"labels":[],"label_agreement":null},{"id":"W2072331709","doi":"10.1158/1538-7445.am2012-3851","title":"Abstract 3851: Killing of Kras mutant colon cancer cells by the αGBP cytokine, a physiological PI3K inhibitor therapeutically effective <i>in vivo</i>","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"KRAS; Cancer research; PI3K/AKT/mTOR pathway; Biology; Cancer; Carcinogenesis; Colorectal cancer; Signal transduction; Cell biology","score_opus":0.2041251391819229,"score_gpt":0.5047044591029548,"score_spread":0.30057931992103193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072331709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98908114,0.00670004,0.000008841231,0.0007939471,0.0009358355,0.0010262858,0.0003479028,0.000021829115,0.0010841745],"genre_scores_gemma":[0.993518,0.004175213,0.000007890427,0.0008373232,0.00063530315,0.00058473443,0.000004776968,0.000028709454,0.00020807797],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99680173,0.0010065981,0.0003476845,0.00037392037,0.000428291,0.0010417489],"domain_scores_gemma":[0.99797654,0.001223371,0.00012215642,0.00021054468,0.00023660963,0.00023077779],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0020111226,0.00023791975,0.00037278346,0.0000968898,0.00032237335,0.000024357809,0.00047080117,0.000306379,0.0021196532],"category_scores_gemma":[0.000045560286,0.0001567202,0.000120681696,0.00050298916,0.00090960076,0.00012324727,0.00017611055,0.0017113445,0.000039945327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009010971,0.0007774576,0.0073503377,0.00008817356,0.00015030561,0.000012093932,0.00061842636,0.00006519466,0.97242045,0.00016556297,0.009904502,0.0075463946],"study_design_scores_gemma":[0.0011171823,0.00020063351,0.013156421,0.00008847675,0.000035052468,0.0000019661788,0.00019858856,0.00014224935,0.91437995,0.00007301772,0.0704152,0.00019127557],"about_ca_topic_score_codex":0.0006576093,"about_ca_topic_score_gemma":0.000099248995,"teacher_disagreement_score":0.0605107,"about_ca_system_score_codex":0.00031182182,"about_ca_system_score_gemma":0.0001643647,"threshold_uncertainty_score":0.9987925},"labels":[],"label_agreement":null},{"id":"W2075023632","doi":"10.1002/mc.20199","title":"Targeting NAD(P)H:Quinone Oxidoreductase (NQO1) in Pancreatic Cancer","year":2006,"lang":"en","type":"erratum","venue":"Molecular Carcinogenesis","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; National Cancer Institute; Foundation of Hope for Research and Treatment of Mental Illness; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs","keywords":"Pancreatic cancer; Biology; Clonogenic assay; NAD+ kinase; Pancreatic Intraepithelial Neoplasia; Cancer research; Pancreas; Cell culture; Cancer; Gemcitabine; Cancer cell; Molecular biology; Cell; Internal medicine; Endocrinology; Biochemistry; Enzyme; Medicine","score_opus":0.06188180249549044,"score_gpt":0.3802559168254417,"score_spread":0.3183741143299512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075023632","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7850881,0.149374,0.00024705444,0.0010423787,0.035741102,0.0016129118,0.0015177848,0.00022723422,0.02514939],"genre_scores_gemma":[0.9069004,0.009772291,0.000416218,0.003236024,0.0038528428,0.0007527627,0.0036154042,0.0004310569,0.071023],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9953869,0.0008566007,0.0008503401,0.001159712,0.00049220264,0.0012542281],"domain_scores_gemma":[0.9984525,0.00009190602,0.00042620563,0.00051091565,0.0001998518,0.00031865065],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00051369827,0.0009152147,0.0011315014,0.0005188298,0.00028507263,0.000063719344,0.00070824847,0.0014829524,0.0011123356],"category_scores_gemma":[0.00007090311,0.00096540456,0.0004492861,0.0006962868,0.00029121875,0.00008419838,0.0002739105,0.0019860151,0.000087612745],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016185736,0.0005297992,0.026613435,0.00058807025,0.0006688967,0.0032025746,0.00012928889,0.0013413455,0.16798985,0.00006545767,0.7970863,0.001623105],"study_design_scores_gemma":[0.0022982256,0.00011796593,0.012452102,0.0003651595,0.0017437886,0.00004687773,0.00010694608,0.0021665301,0.061210513,0.00014896374,0.91730845,0.0020345002],"about_ca_topic_score_codex":0.0030135096,"about_ca_topic_score_gemma":0.00030550544,"teacher_disagreement_score":0.13960171,"about_ca_system_score_codex":0.00052044855,"about_ca_system_score_gemma":0.00055894605,"threshold_uncertainty_score":0.9998133},"labels":[],"label_agreement":null},{"id":"W2075417276","doi":"10.1139/v05-121","title":"Ambident reactivity of phenoxyl radicals in DNA adduction","year":2005,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; University of Guelph","keywords":"Chemistry; Radical; Deoxyguanosine; Reactivity (psychology); Photochemistry; Adduct; Peroxide; Reactive oxygen species; Peroxidase; Redox; Organic chemistry; Biochemistry; Enzyme","score_opus":0.07732918907146771,"score_gpt":0.37966971822449863,"score_spread":0.3023405291530309,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075417276","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99364936,0.0007253688,0.000013106973,0.001152093,0.00034864162,0.000037736692,0.000017774262,0.0000022761417,0.004053654],"genre_scores_gemma":[0.9988871,0.000082835046,0.000047297133,0.00021520509,0.0004595591,8.756087e-7,0.0000022970944,0.0000074112986,0.00029738582],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991672,0.000067365145,0.00035395875,0.00009282021,0.00009325457,0.00022538743],"domain_scores_gemma":[0.9990969,0.00004953725,0.0002637917,0.00008020499,0.0000927285,0.0004168646],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00043001643,0.0000933885,0.0002136431,0.00008164544,0.000050549017,0.000008640493,0.00018251527,0.00016134877,0.0014872024],"category_scores_gemma":[0.000083705425,0.00009496951,0.0000887488,0.00010692755,0.0001709132,0.00011722496,0.000008439183,0.00054181984,0.000005208668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010747301,0.00018892615,0.044077057,0.00005847152,0.000088333,0.00017922811,0.0003729897,0.00013318432,0.9267542,0.000021279475,0.009045675,0.018973218],"study_design_scores_gemma":[0.0010240613,0.000030243702,0.020954128,0.000056178727,0.000035028406,0.00022113512,0.00016018134,0.00005033349,0.80273753,0.00012682407,0.1744826,0.00012178112],"about_ca_topic_score_codex":0.00032805937,"about_ca_topic_score_gemma":0.001082562,"teacher_disagreement_score":0.16543692,"about_ca_system_score_codex":0.00023973825,"about_ca_system_score_gemma":0.00055597443,"threshold_uncertainty_score":0.9994256},"labels":[],"label_agreement":null},{"id":"W2078248627","doi":"10.1021/np020144m","title":"Antineoplastic Agents. 488. Isolation and Structure of Yukonin from a Yukon Territory Fungus","year":2002,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Cancer Institute","keywords":"Fungus; Lactone; Isolation (microbiology); Biology; Terpene; Stereochemistry; Cancer cell lines; Bioassay; Cell culture; Microbiology; Chemistry; Botany; Cancer; Cancer cell; Genetics","score_opus":0.08260745516612879,"score_gpt":0.36198595609904266,"score_spread":0.2793785009329139,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078248627","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98623157,0.009297671,0.000009136126,0.0009715644,0.003217754,0.00011095267,0.000047898175,0.000008151337,0.00010527886],"genre_scores_gemma":[0.99752265,0.00042743213,0.00051411294,0.00024619864,0.0009909049,1.9672026e-7,0.0000076935485,0.000011472531,0.0002793521],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988575,0.00017577996,0.00041153416,0.00017864523,0.00019272287,0.0001838176],"domain_scores_gemma":[0.998926,0.00012535945,0.00052731304,0.00009314264,0.00023792112,0.000090266774],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001510488,0.00015959676,0.00029911863,0.00012930838,0.00009560514,0.000018135226,0.00015773092,0.00014860976,0.00039322226],"category_scores_gemma":[0.00017411918,0.00012331358,0.0000663671,0.00014123142,0.0001281019,0.00024644035,0.000046486213,0.0007736451,0.0000043123114],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040033623,0.00023834914,0.03428079,0.000088241984,0.00030246176,0.00008828902,0.0006432367,0.000047057216,0.93704283,0.000032716875,0.0174728,0.00936288],"study_design_scores_gemma":[0.005969032,0.00087630004,0.4980446,0.0002394321,0.00073273125,0.00074487773,0.0001946925,0.009381008,0.42700198,0.0006527149,0.055553485,0.000609152],"about_ca_topic_score_codex":0.000007933392,"about_ca_topic_score_gemma":0.000004221518,"teacher_disagreement_score":0.5100409,"about_ca_system_score_codex":0.000030643634,"about_ca_system_score_gemma":0.000024834773,"threshold_uncertainty_score":0.5028582},"labels":[],"label_agreement":null},{"id":"W2078657061","doi":"10.1002/ijc.26183","title":"Cisplatin increases B‐cell‐lymphoma‐2 expression <i>via</i> activation of protein kinase C and Akt2 in endometrial cancer cells","year":2011,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Cisplatin; Apoptosis; Cancer research; Protein kinase B; AKT2; Chemistry; Cancer cell; Protein kinase C; Cell culture; Small hairpin RNA; Molecular biology; Kinase; Biology; Cancer; AKT1; Cell biology; Medicine; Internal medicine; Gene knockdown; Chemotherapy; Biochemistry","score_opus":0.0971827784483581,"score_gpt":0.411684430279313,"score_spread":0.3145016518309549,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078657061","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960512,0.0016425888,0.00020972725,0.00011631322,0.001199183,0.00015282765,0.00005663978,0.0000036577364,0.0005678485],"genre_scores_gemma":[0.99781513,0.001166841,0.00031294834,0.00020611113,0.00039282165,0.000018961808,0.0000020143596,0.00001014916,0.00007503532],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886423,0.00016104079,0.00045101103,0.00012069894,0.00027367452,0.00012935323],"domain_scores_gemma":[0.99880373,0.00013038407,0.00061039784,0.0000451904,0.00032356798,0.000086720975],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003181528,0.000118026655,0.00021426374,0.00028864644,0.000031961576,0.000010755843,0.000227702,0.000106159496,0.00094379357],"category_scores_gemma":[0.00004482556,0.000100034966,0.00007269501,0.00012154337,0.00009534167,0.0002465899,0.00006226292,0.00022271852,0.0000012074623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0035761823,0.0007796558,0.042153858,0.00002729257,0.0001485828,0.000052041527,0.0003669709,0.00006189747,0.9136637,0.000046312736,0.00034375972,0.03877975],"study_design_scores_gemma":[0.00574168,0.00010439446,0.02046917,0.00022585863,0.000043456115,0.0000086696255,0.000051992254,0.00013981647,0.9685921,0.00026433953,0.0042563337,0.00010218384],"about_ca_topic_score_codex":0.00076355983,"about_ca_topic_score_gemma":0.000053829634,"teacher_disagreement_score":0.05492841,"about_ca_system_score_codex":0.00013265654,"about_ca_system_score_gemma":0.0001430639,"threshold_uncertainty_score":0.9999695},"labels":[],"label_agreement":null},{"id":"W2082627431","doi":"10.1139/y2012-134","title":"Anticancer activity and mechanism of juglone on human cervical carcinoma HeLa cells","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Juglone; HeLa; Mechanism (biology); Cervical carcinoma; Carcinoma; Chemistry; Cancer research; Cell biology; In vitro; Biology; Pharmacology; Cervical cancer; Biochemistry; Medicine; Cancer; Internal medicine","score_opus":0.10711637546538914,"score_gpt":0.4008443807959901,"score_spread":0.29372800533060095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082627431","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950542,0.0010794002,0.000012586948,0.00054479524,0.0024897088,0.00014005648,0.00007183283,0.0000044178823,0.00060303573],"genre_scores_gemma":[0.9971988,0.0002708555,0.00003413039,0.0017389442,0.0006627773,0.000003994073,0.0000026307791,0.000015694653,0.00007214509],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99826944,0.0005764014,0.00032349819,0.00019262072,0.000069779635,0.0005682347],"domain_scores_gemma":[0.998359,0.00026113784,0.0003135803,0.00008189433,0.00011571469,0.00086862134],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00050745264,0.00021970601,0.0005092648,0.00023778703,0.00030350906,0.0000054497586,0.0001853373,0.0003365116,0.0024297806],"category_scores_gemma":[0.000011466756,0.00019648824,0.000093211434,0.00010483922,0.00077509944,0.00013459449,0.00004488512,0.00083164015,0.0000081632315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032885224,0.000209692,0.014812885,0.00009811282,0.00024313739,0.000048373622,0.000466033,0.000005744234,0.97711784,0.004351859,0.0016617136,0.00065574783],"study_design_scores_gemma":[0.001957336,0.0007993813,0.11124655,0.000013757361,0.00028442807,0.00014239532,0.00007149137,0.000058236754,0.8761063,0.0010609024,0.0080432715,0.00021591889],"about_ca_topic_score_codex":0.0003027316,"about_ca_topic_score_gemma":0.00016761101,"teacher_disagreement_score":0.10101152,"about_ca_system_score_codex":0.000056655022,"about_ca_system_score_gemma":0.00020069367,"threshold_uncertainty_score":0.9984821},"labels":[],"label_agreement":null},{"id":"W2082766071","doi":"10.1139/w04-088","title":"Use of 1,4-naphthoquinones for control of<i>Erwinia carotovora</i>","year":2004,"lang":"en","type":"article","venue":"Canadian Journal of Microbiology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Erwinia; Microbiology; Biology; Bacteria; Chemistry; Genetics","score_opus":0.13154620109436035,"score_gpt":0.3720925865317194,"score_spread":0.24054638543735904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082766071","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99281496,0.0014616437,0.0016610061,0.00086967833,0.0016552779,0.00031476258,0.0011378509,0.0000027316398,0.000082061364],"genre_scores_gemma":[0.99802506,0.00006110499,0.0007078846,0.0009718861,0.0001423857,0.0000034777877,0.000012950734,0.000013228576,0.0000620189],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99879277,0.00016343669,0.00055899104,0.00011671183,0.00002517439,0.00034292002],"domain_scores_gemma":[0.9983698,0.00025558643,0.0005213701,0.00009910817,0.0004515094,0.00030259992],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038881312,0.0001400538,0.00048461577,0.00024364171,0.0000898408,0.00000600064,0.00025879935,0.0002567511,0.00016124836],"category_scores_gemma":[0.000117669486,0.0001238689,0.00023917423,0.0001006401,0.00051743997,0.00007675774,0.000009517944,0.00028544216,0.000003482484],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044110333,0.00009566585,0.02447866,0.000055881632,0.00044223553,0.00007193137,0.00026033752,0.000766972,0.96737826,0.0012711419,0.0038800423,0.0008577867],"study_design_scores_gemma":[0.008170234,0.0015816162,0.0052540344,0.000113257076,0.00042422971,0.001144043,0.00015446225,0.000020900536,0.45297402,0.00077714707,0.52906704,0.00031903642],"about_ca_topic_score_codex":0.0006776178,"about_ca_topic_score_gemma":0.0023370066,"teacher_disagreement_score":0.52518696,"about_ca_system_score_codex":0.00007438326,"about_ca_system_score_gemma":0.0009479592,"threshold_uncertainty_score":0.5051227},"labels":[],"label_agreement":null},{"id":"W2084996945","doi":"10.2478/bf02476181","title":"Antiinflammatory, analgesic and kinase inhibition activities of some acridine derivatives","year":2004,"lang":"en","type":"article","venue":"Open Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Indian Council for Cultural Relations; University of Alberta","keywords":"Chemistry; Condensation; Analgesic; Acridine; Aryl; Condensation reaction; Medicinal chemistry; Organic chemistry; Stereochemistry; Pharmacology; Catalysis; Medicine","score_opus":0.08792190833813561,"score_gpt":0.40737614716137405,"score_spread":0.3194542388232384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084996945","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99320537,0.0003461616,0.000014049584,0.00044418973,0.00008448544,0.00014742759,0.00005761086,0.000017612028,0.005683111],"genre_scores_gemma":[0.99881923,0.0002760809,0.00014080602,0.00019485861,0.000094854804,0.000014680681,0.000027119102,0.000011584055,0.00042077943],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993174,0.000038748258,0.00017502977,0.00021588677,0.000073876916,0.00017903883],"domain_scores_gemma":[0.99958116,0.00004507158,0.00013208862,0.00011200406,0.000034031425,0.00009566608],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016305008,0.00014230245,0.0002105731,0.000020415602,0.00015498401,0.00003560867,0.00016481926,0.00012807091,0.0003991565],"category_scores_gemma":[0.00001956748,0.00013963369,0.00003850296,0.00007595605,0.0003183266,0.00030901135,0.0002129833,0.00022369713,0.0000043468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014231725,0.00021399425,0.003592191,0.00015770918,0.00007368974,0.00004147733,0.00021043039,0.000010562945,0.9935605,0.00059457,0.0003255937,0.0010769492],"study_design_scores_gemma":[0.001580059,0.000033279834,0.0041405964,0.000057963764,0.00003416638,0.000020077152,0.0003606019,0.000012949675,0.9895366,0.0011791204,0.0028882357,0.00015637784],"about_ca_topic_score_codex":0.000020628228,"about_ca_topic_score_gemma":0.0000023158573,"teacher_disagreement_score":0.005613884,"about_ca_system_score_codex":0.000034247656,"about_ca_system_score_gemma":0.00006575194,"threshold_uncertainty_score":0.56940967},"labels":[],"label_agreement":null},{"id":"W2085704486","doi":"10.1007/s12079-009-0084-0","title":"The lectin concanavalin‐A signals MT1‐MMP catalytic independent induction of COX‐2 through an IKKγ/NF‐κB‐dependent pathway","year":2010,"lang":"en","type":"article","venue":"Journal of Cell Communication and Signaling","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"National Cancer Institute; Canadian Institutes of Health Research; Fonds Québécois de la Recherche sur la Nature et les Technologies; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Concanavalin A; Lectin; NF-κB; Matrix metalloproteinase; Inflammation; Computer science; Cancer research; Medicine; Chemistry; Immunology; Biochemistry; Internal medicine; In vitro","score_opus":0.1165769033523747,"score_gpt":0.4088533024446194,"score_spread":0.29227639909224473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085704486","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938488,0.0020558992,0.000416681,0.0006786361,0.00089814735,0.00018041089,0.000008795261,0.000010883832,0.0019017317],"genre_scores_gemma":[0.99660146,0.0021036833,0.00063847733,0.00029291774,0.00016529154,0.0000038902,0.000009007659,0.000016481588,0.0001687895],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977321,0.00084023294,0.0007702302,0.00014148431,0.00029806563,0.00021790892],"domain_scores_gemma":[0.99724644,0.0006979347,0.0010693838,0.00033405964,0.0004926282,0.00015954842],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002765768,0.00016904304,0.00030042024,0.00008758781,0.00066962384,0.00007908913,0.0006068804,0.00022819113,0.00018673329],"category_scores_gemma":[0.00009019756,0.0001267592,0.00011421005,0.00013535496,0.00033842985,0.00038354553,0.00011545306,0.0016103387,0.0000038289095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028686153,0.0004138341,0.0022848432,0.000029253397,0.00014022847,0.000007736974,0.0021620244,0.00019515204,0.98696065,0.0017909631,0.00022120641,0.0055072624],"study_design_scores_gemma":[0.0019402755,0.0003469668,0.0011490735,0.000046646357,0.00017524009,0.00014465253,0.0029019732,0.00091366336,0.9619524,0.0028334914,0.027378423,0.00021720737],"about_ca_topic_score_codex":0.00007623029,"about_ca_topic_score_gemma":0.00012180329,"teacher_disagreement_score":0.027157217,"about_ca_system_score_codex":0.000040549126,"about_ca_system_score_gemma":0.00017225092,"threshold_uncertainty_score":0.699621},"labels":[],"label_agreement":null},{"id":"W2086365050","doi":"10.1021/jp040280v","title":"Spectroscopic Studies of the Intermediates in the Conversion of 1,4,11,12-Tetrahydro-9,10-anthraquinone to 9,10-Anthraquinone by Reaction with Oxygen under Basic Conditions","year":2004,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry A","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick","funders":"","keywords":"Chemistry; Anthraquinone; Electron paramagnetic resonance; Radical ion; Nuclear magnetic resonance spectroscopy; Photochemistry; Spectroscopy; Radical; Inorganic chemistry; Ion; Medicinal chemistry; Organic chemistry; Nuclear magnetic resonance","score_opus":0.06611767596142512,"score_gpt":0.3999050515520359,"score_spread":0.3337873755906108,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086365050","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962441,0.000273801,0.00002711699,0.0027866382,0.00008939513,0.00017110216,0.000035174216,0.0000039503134,0.00036876596],"genre_scores_gemma":[0.99923474,0.000108694614,0.0000051946827,0.00027457657,0.00019202218,0.0000047480185,0.000004055498,0.000009229293,0.00016676675],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988407,0.0002118804,0.0003446889,0.000111628135,0.0002932097,0.00019790868],"domain_scores_gemma":[0.9986665,0.00048400596,0.00044712628,0.00018863467,0.00015069942,0.00006301575],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041240582,0.00016709176,0.0003489272,0.00002812063,0.00014993109,0.000006469492,0.0004729528,0.00007115882,0.00016239875],"category_scores_gemma":[0.000059863865,0.00008143543,0.00013576965,0.00024549436,0.0008136182,0.000086510125,0.00007986347,0.0005581562,0.000005708478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005488566,0.000896056,0.000524395,0.00010160957,0.00023793224,0.000006948619,0.0017548449,0.00071682205,0.9935899,0.000039157643,0.0015594846,0.00002400963],"study_design_scores_gemma":[0.0016337453,0.00045030413,0.0055568498,0.00018347554,0.00030785985,0.00004415108,0.0031026616,0.000043491353,0.9875507,0.00045188467,0.0005811542,0.00009376607],"about_ca_topic_score_codex":0.000014103205,"about_ca_topic_score_gemma":0.0000065529885,"teacher_disagreement_score":0.006039227,"about_ca_system_score_codex":0.000097642056,"about_ca_system_score_gemma":0.00007719991,"threshold_uncertainty_score":0.33208403},"labels":[],"label_agreement":null},{"id":"W2086643924","doi":"10.1139/v06-054","title":"From enolates to anthraquinones","year":2006,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Anthraquinones; Anthraquinone; Quinone; Enone; Naphthoquinone; Organic chemistry; Medicinal chemistry","score_opus":0.05671935041103224,"score_gpt":0.3638036128629674,"score_spread":0.3070842624519352,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086643924","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9870078,0.0010490094,0.0000313291,0.0014079942,0.0007391427,0.000031239648,0.00010607046,0.000005444271,0.009621984],"genre_scores_gemma":[0.9968674,0.000011307439,0.00014105605,0.0005468096,0.0013298612,8.329717e-7,0.000010559707,0.000010548615,0.001081611],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929136,0.000028533119,0.00024303478,0.0001016725,0.000068809386,0.00026658527],"domain_scores_gemma":[0.9990265,0.000056054676,0.00011657923,0.00007843541,0.000118928234,0.00060354144],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001227889,0.000109145694,0.0001660401,0.00005163521,0.00012271163,0.000032154865,0.00024988758,0.00014094688,0.0034592652],"category_scores_gemma":[0.00003241406,0.000104834544,0.00008039096,0.00009292078,0.00009594663,0.000058118185,0.0000108500435,0.00033214074,0.000045058256],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006554178,0.000063523374,0.08953502,0.000018709414,0.00012002189,0.0008795232,0.0003049085,0.00012713163,0.79223114,0.000026334337,0.11372281,0.0029053288],"study_design_scores_gemma":[0.0005067075,0.000027538323,0.011651731,0.00003148344,0.000041310686,0.00011077052,0.00017210822,0.0000136050185,0.5722386,0.0006437207,0.4144001,0.00016231342],"about_ca_topic_score_codex":0.0025108396,"about_ca_topic_score_gemma":0.0012108006,"teacher_disagreement_score":0.3006773,"about_ca_system_score_codex":0.00008681236,"about_ca_system_score_gemma":0.0003644912,"threshold_uncertainty_score":0.9974517},"labels":[],"label_agreement":null},{"id":"W2088983187","doi":"10.1016/j.bmc.2008.06.023","title":"The discovery of small molecule chemical probes of Bcl-XL and Mcl-1","year":2008,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Steacie Institute for Molecular Sciences; Biotechnology Research Institute; McGill University; Ontario Institute for Cancer Research","funders":"Broad Institute; Abbott Laboratories","keywords":"Chemistry; Small molecule; In silico; Molecule; Chemical library; Scaffold; Combinatorial chemistry; Stereochemistry; Bcl-xL; Drug discovery; Biophysics; Biochemistry; Organic chemistry; Database","score_opus":0.08559728218779089,"score_gpt":0.3535175244373098,"score_spread":0.26792024224951894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2088983187","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99355274,0.0038940953,0.000028554703,0.00047483048,0.00014283707,0.00010030214,0.000025521638,0.000014147314,0.0017669648],"genre_scores_gemma":[0.9976896,0.0011512064,0.000040006486,0.00013241346,0.00016230001,0.000005354311,0.000009619063,0.000012299518,0.0007971694],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990656,0.000045448473,0.0003018933,0.00020311643,0.00015396206,0.00022999119],"domain_scores_gemma":[0.9993008,0.0001815906,0.00016603892,0.00016467889,0.00007766638,0.00010924733],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002155734,0.00015215707,0.00024573188,0.00001231859,0.00013357474,0.0000042825172,0.00025451658,0.00017414759,0.00011559228],"category_scores_gemma":[0.00011554844,0.00010610947,0.00006499357,0.00010980394,0.0011288697,0.000032070893,0.000112270944,0.0003442035,0.0000022085642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015841858,0.00017893754,0.008482269,0.00016259482,0.00009514265,0.000019834932,0.00017132392,8.622727e-8,0.9888031,0.0000555661,0.0013664714,0.00050623843],"study_design_scores_gemma":[0.00081556314,0.00004990082,0.002839057,0.000037524176,0.00007937865,0.00014316798,0.0002001065,0.00003456925,0.99212563,0.00004902193,0.0035198207,0.00010623921],"about_ca_topic_score_codex":0.000011411123,"about_ca_topic_score_gemma":8.698317e-7,"teacher_disagreement_score":0.005643212,"about_ca_system_score_codex":0.000021976492,"about_ca_system_score_gemma":0.000112980335,"threshold_uncertainty_score":0.4327019},"labels":[],"label_agreement":null},{"id":"W2091801473","doi":"10.1016/j.ijpharm.2007.06.032","title":"Polymeric micelles for the solubilization and delivery of STAT3 inhibitor cucurbitacins in solid tumors","year":2007,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":89,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Ministry of Health and Medical Education","keywords":"Solubilization; Micelle; Chemistry; Pharmacology; Dosage form; Chromatography; Medicine; Organic chemistry; Aqueous solution; Biochemistry","score_opus":0.11955863341718823,"score_gpt":0.46888409520869034,"score_spread":0.34932546179150215,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091801473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98786825,0.0039103944,0.004325011,0.00090611837,0.0025646242,0.0002096931,0.0000616415,0.0000051786906,0.0001491014],"genre_scores_gemma":[0.9959605,0.0023122632,0.00039583843,0.00076288247,0.0004889783,0.0000022767929,0.0000050180047,0.00001350679,0.0000587839],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99864763,0.00008443727,0.00068498374,0.00010985073,0.0002582102,0.00021490928],"domain_scores_gemma":[0.997953,0.00084269664,0.0005377652,0.000050731367,0.0005167336,0.00009907454],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011534797,0.0001291685,0.00020785576,0.0002578598,0.00007624799,0.00002040547,0.00032646235,0.000070349626,0.00006663914],"category_scores_gemma":[0.00009046524,0.00010082633,0.00010674588,0.00013378411,0.00020739183,0.00016448539,0.00007260761,0.0003713348,0.0000010928296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003815823,0.0010313183,0.14854465,0.00008952908,0.0008962828,0.00015702737,0.0020577766,0.0013699835,0.73994267,0.0010445997,0.001066625,0.0999837],"study_design_scores_gemma":[0.0057649785,0.00023390487,0.0221554,0.00011608918,0.0002373613,0.00022610626,0.0013747375,0.016127767,0.9025501,0.00040206432,0.050581478,0.00023000027],"about_ca_topic_score_codex":0.000013831313,"about_ca_topic_score_gemma":0.000030659547,"teacher_disagreement_score":0.16260745,"about_ca_system_score_codex":0.00007678935,"about_ca_system_score_gemma":0.00010352754,"threshold_uncertainty_score":0.41115782},"labels":[],"label_agreement":null},{"id":"W2091840812","doi":"10.5206/wurjhns.2012-13.7","title":"Western Faculty Profile: Dr. Moshmi Bhattacharya","year":2012,"lang":"en","type":"article","venue":"Western Undergraduate Research Journal Health and Natural Sciences","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"Western University","funders":"Robarts Research Institute; Strong","keywords":"Breast cancer; Oncology; Medicine; Cancer; Internal medicine","score_opus":0.4009799391075765,"score_gpt":0.5868521287542784,"score_spread":0.18587218964670188,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091840812","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9051814,0.02789553,0.000028942932,0.0634844,0.0021762922,0.00042212338,0.000029606326,0.000039659455,0.00074203237],"genre_scores_gemma":[0.9858926,0.007387843,0.000117671625,0.0027833981,0.0011304767,0.000011953605,0.0000141827995,0.000014412336,0.0026474688],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9942777,0.001714402,0.00044918127,0.00034100973,0.0009945922,0.0022230968],"domain_scores_gemma":[0.99686116,0.0004210227,0.00023541559,0.0001046239,0.00020532879,0.0021724673],"candidate_categories":["sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.007370026,0.00025162878,0.00032643604,0.0003162331,0.0033001527,0.00028130997,0.00051829556,0.00016724046,0.00007489741],"category_scores_gemma":[0.00010505471,0.00017135702,0.00008516838,0.0006847589,0.0011429465,0.0011648919,0.00026268276,0.0026283292,0.000143235],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002249509,0.0003676299,0.91627157,0.00013563424,0.00006375221,0.000023339362,0.0010592797,0.000001380735,0.0007219249,0.00092139904,0.01155562,0.068653546],"study_design_scores_gemma":[0.0027372197,0.0019403017,0.39001432,0.0002796978,0.000034889974,0.002527577,0.0020398872,0.00056943746,0.0019798637,0.00215469,0.59486926,0.00085286365],"about_ca_topic_score_codex":0.000093510316,"about_ca_topic_score_gemma":0.00006633963,"teacher_disagreement_score":0.58331364,"about_ca_system_score_codex":0.00015985325,"about_ca_system_score_gemma":0.00045145233,"threshold_uncertainty_score":0.99967265},"labels":[],"label_agreement":null},{"id":"W2092140599","doi":"10.1002/chin.200208125","title":"ChemInform Abstract: The Diels—Alder Reactions of Quinone Imine Ketals: A Versatile Synthesis of Highly Substituted 5‐Methoxyindoles.","year":2002,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Imine; Quinone; Diels–Alder reaction; Organic chemistry; Combinatorial chemistry; Catalysis","score_opus":0.13152598298506596,"score_gpt":0.37168177849104594,"score_spread":0.24015579550597999,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092140599","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.23812401,0.0006744643,0.0000011413317,0.0006058534,0.0005245495,0.00039475106,0.00019893375,0.000063433814,0.7594128],"genre_scores_gemma":[0.9893382,0.0006557269,0.000040244322,0.00016122418,0.000121972,0.000052075084,0.000023996481,0.000018453668,0.009588086],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99849355,0.0000015093175,0.0006934138,0.00019779766,0.00024140858,0.00037232935],"domain_scores_gemma":[0.9980235,0.0007367864,0.00053638243,0.00037102916,0.00019163138,0.000140636],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00046165107,0.00025746063,0.00042028853,0.00010540683,0.00018642587,0.000013108709,0.00043163914,0.0002868984,0.007214464],"category_scores_gemma":[0.0002741855,0.00019479956,0.00023712702,0.0003328263,0.0006139062,0.00024355763,0.00010244298,0.0004856579,0.00007876282],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048877526,0.0016120094,0.0012227208,0.00094398647,0.0012093346,0.000024614457,0.0035162119,0.0000093000535,0.258211,0.001230586,0.087286025,0.64424545],"study_design_scores_gemma":[0.0007192298,0.000030380721,0.0030487983,0.00006297357,0.00020372031,0.000019909277,0.00048788052,0.00013728571,0.84399635,0.000027287886,0.15107015,0.00019604081],"about_ca_topic_score_codex":0.00005497186,"about_ca_topic_score_gemma":0.000008046461,"teacher_disagreement_score":0.7512142,"about_ca_system_score_codex":0.00006907114,"about_ca_system_score_gemma":0.00004350354,"threshold_uncertainty_score":0.99369305},"labels":[],"label_agreement":null},{"id":"W2092211760","doi":"10.1016/j.ejmech.2010.05.046","title":"Design and synthesis of chloroquine analogs with anti-breast cancer property","year":2010,"lang":"en","type":"article","venue":"European Journal of Medicinal Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"NOSM University; Laurentian University; Sudbury Regional Hospital","funders":"Ontario Ministry of Research and Innovation","keywords":"Chemistry; Trifluoromethyl; Breast cancer; Amine gas treating; Cisplatin; Cancer; Cancer cell; Chloroquine; Stereochemistry; Tertiary amine; Pharmacology; Cell culture; Cancer cell lines; Cell growth; Chemical synthesis; Cancer research; Chemotherapy; In vitro; Internal medicine; Biochemistry; Medicine; Immunology; Biology; Organic chemistry; Malaria","score_opus":0.059303318050520824,"score_gpt":0.3495110839429834,"score_spread":0.2902077658924626,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092211760","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948898,0.0004123135,0.000294382,0.0012483085,0.0002505161,0.00005928609,0.000016863289,0.0000072737284,0.00282127],"genre_scores_gemma":[0.9980788,0.00043188917,0.00059140235,0.00017832461,0.0005063783,9.91836e-7,6.5982266e-7,0.00001946379,0.00019204905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893427,0.00021121411,0.0003409611,0.00013507763,0.00019907037,0.00017940775],"domain_scores_gemma":[0.99886906,0.00013733562,0.00041599205,0.0000954704,0.00024139414,0.00024074051],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012456357,0.00015420308,0.00030638528,0.00003762544,0.000077395154,0.000008655446,0.00024386363,0.000055350258,0.000830728],"category_scores_gemma":[0.00006925127,0.00008594781,0.000047030546,0.00008959242,0.00048134296,0.00006803825,0.00003877126,0.0008305131,0.0000019011961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009942891,0.0002550283,0.02306141,0.00015388105,0.00026462125,0.000661346,0.00013866663,0.000027314414,0.9511247,0.0000017610151,0.0016543785,0.021662556],"study_design_scores_gemma":[0.0034953635,0.00041225893,0.06918979,0.00047525507,0.0006389815,0.0057186577,0.00023363788,0.0002876618,0.90589654,0.00000613101,0.013362612,0.000283129],"about_ca_topic_score_codex":0.0000036303354,"about_ca_topic_score_gemma":5.002875e-7,"teacher_disagreement_score":0.046128374,"about_ca_system_score_codex":0.000012156283,"about_ca_system_score_gemma":0.00010332063,"threshold_uncertainty_score":0.9095889},"labels":[],"label_agreement":null},{"id":"W2092539716","doi":"10.1089/jmf.2009.0279","title":"<i>Genipa americana</i> (Rubiaceae) Fruit Extract Affects Mitogen-Activated Protein Kinase Cell Pathways in Human Trophoblast–Derived BeWo Cells: Implications for Placental Development","year":2011,"lang":"en","type":"article","venue":"Journal of Medicinal Food","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke; Université du Québec à Montréal","funders":"Universidade Estadual de Santa Cruz","keywords":"Biology; Cell growth; MAPK/ERK pathway; Cell biology; Viability assay; Kinase; p38 mitogen-activated protein kinases; Protein kinase A; Trophoblast; Cell culture; Mitogen-activated protein kinase; Cell; Biochemistry; Placenta; Fetus","score_opus":0.16508885189616299,"score_gpt":0.37383337928749744,"score_spread":0.20874452739133445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092539716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99604386,0.0006482812,0.00063824747,0.0002567804,0.0008703103,0.00086725934,0.000060019032,0.00001995105,0.00059528626],"genre_scores_gemma":[0.9968784,0.00006790115,0.0021795894,0.0003730318,0.0002681823,0.00007970798,0.000015004089,0.00003752096,0.00010069802],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979192,0.0002784295,0.00073302636,0.00028945613,0.00024277884,0.000537121],"domain_scores_gemma":[0.99829584,0.00016272496,0.00078291266,0.00014640205,0.00019207517,0.00042004295],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00065127783,0.0003140551,0.0005144513,0.00026459023,0.0002949671,0.000014458971,0.0004111234,0.00020493164,0.0002534212],"category_scores_gemma":[0.00004178752,0.00027227087,0.00019246146,0.00025013756,0.00019173503,0.00015067114,0.000059640966,0.0008482088,0.0000076513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013589204,0.0015425781,0.0033354869,0.0000999316,0.00020139324,0.00009173449,0.0022217461,0.0000056860026,0.9847534,0.000059464233,0.0014614434,0.0048682364],"study_design_scores_gemma":[0.00555367,0.0026606556,0.01517968,0.00013218434,0.00013618979,0.00007007906,0.000940996,0.00001605307,0.9599172,0.00014126801,0.014956924,0.0002951179],"about_ca_topic_score_codex":0.00001611919,"about_ca_topic_score_gemma":0.000048206635,"teacher_disagreement_score":0.024836197,"about_ca_system_score_codex":0.00026696073,"about_ca_system_score_gemma":0.0003873922,"threshold_uncertainty_score":0.99997294},"labels":[],"label_agreement":null},{"id":"W2093463529","doi":"10.1002/chin.200119203","title":"ChemInform Abstract: Isobenzofurans and ortho‐Benzoquinone Monoketals in Syntheses of Xestoquinone and Its 9‐ and 10‐Methoxy Derivatives.","year":2001,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Chemistry; Benzoquinone; Combinatorial chemistry; Service (business); Information retrieval; Stereochemistry; Organic chemistry; Computer science; Business","score_opus":0.12478252919360786,"score_gpt":0.3919036405730694,"score_spread":0.2671211113794616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093463529","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81704843,0.0027156367,2.476065e-7,0.00018377016,0.000059744354,0.00025435642,0.000047027057,0.000024072044,0.1796667],"genre_scores_gemma":[0.9882132,0.0052689263,0.00004279401,0.00022158773,0.000042707343,0.000023790355,0.0000142237595,0.000017913426,0.0061548846],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99869484,0.0000014392022,0.00048477337,0.00029306806,0.00012665495,0.00039925685],"domain_scores_gemma":[0.998922,0.00042461767,0.00021881855,0.000127062,0.00008122118,0.00022626351],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00044839297,0.00029052576,0.00045545542,0.00014589484,0.00011260209,0.000026790598,0.00013826862,0.00029252423,0.0013189139],"category_scores_gemma":[0.00017126961,0.00027155096,0.00004767813,0.00020437586,0.00038095078,0.0004097375,0.00015567846,0.00036774031,0.000008273578],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009259083,0.00047505816,0.048392355,0.0008531241,0.00028087737,0.00009996274,0.0042552254,8.43564e-7,0.13272126,0.00073660334,0.0019304443,0.8093283],"study_design_scores_gemma":[0.0029352808,0.0001956935,0.16502413,0.00023797293,0.00012943188,0.00024147461,0.0015962789,0.00020759428,0.7323441,0.00019027309,0.09619181,0.0007059582],"about_ca_topic_score_codex":0.000026447922,"about_ca_topic_score_gemma":0.000021140013,"teacher_disagreement_score":0.80862236,"about_ca_system_score_codex":0.000030318639,"about_ca_system_score_gemma":0.00003803124,"threshold_uncertainty_score":0.99997365},"labels":[],"label_agreement":null},{"id":"W2093609735","doi":"10.1016/s0014-2999(99)00892-4","title":"The effect of protein kinase C activation on colonic epithelial cellular integrity","year":2000,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Protein kinase C; Staurosporine; Phorbol; Protein kinase A; Protein kinase inhibitor; Molecular biology; Superoxide dismutase; Cytosol; Biochemistry; Chemistry; Biology; Kinase; Oxidative stress; Enzyme","score_opus":0.05506748728462322,"score_gpt":0.37848500692288206,"score_spread":0.3234175196382588,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093609735","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99122137,0.00033816195,0.000043912794,0.0016752209,0.0015565704,0.00041288868,0.000016428876,0.000016347349,0.0047191256],"genre_scores_gemma":[0.9974666,0.0002930119,0.000032871456,0.0005570973,0.000825931,0.000006141933,0.0000026052683,0.000028684171,0.00078703417],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9930768,0.0055206097,0.0006559907,0.0001806325,0.0002145899,0.0003513757],"domain_scores_gemma":[0.998217,0.0007545622,0.00060273113,0.0001209924,0.00015317615,0.00015153862],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0033525908,0.00023334572,0.00036118313,0.00010934373,0.00033477243,0.000018286417,0.0005773015,0.000092565926,0.0022829121],"category_scores_gemma":[0.00010689288,0.00015013487,0.00023796744,0.00017829295,0.00041898072,0.00010186503,0.000050960876,0.0015892822,0.00017414014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008338038,0.00040420692,0.00050861476,0.000035149384,0.0003496621,0.00035280088,0.00014507376,0.00021008524,0.90486616,0.00008831008,0.009084055,0.07561784],"study_design_scores_gemma":[0.0037919753,0.0042880257,0.0012090337,0.00003688858,0.00015580417,0.000036612266,0.000013856862,0.00014577374,0.750506,0.000025076177,0.23967536,0.00011562376],"about_ca_topic_score_codex":0.0000025117106,"about_ca_topic_score_gemma":4.6967708e-7,"teacher_disagreement_score":0.2305913,"about_ca_system_score_codex":0.000077102464,"about_ca_system_score_gemma":0.00007101894,"threshold_uncertainty_score":0.99862915},"labels":[],"label_agreement":null},{"id":"W2094761209","doi":"10.1007/s12013-007-0037-2","title":"An Overview of DNA and RNA Bindings to Antioxidant Flavonoids","year":2007,"lang":"en","type":"article","venue":"Cell Biochemistry and Biophysics","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":110,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"","keywords":"DNA; Delphinidin; Chemistry; Kaempferol; RNA; Transfer RNA; Stereochemistry; Flavonoid; Quercetin; Biochemistry; Antioxidant; Cyanidin","score_opus":0.0909659849509268,"score_gpt":0.4091885814139949,"score_spread":0.3182225964630681,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094761209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967495,0.0010417507,0.000056220768,0.000073619514,0.00017724428,0.00010596175,0.000063361884,0.000021631207,0.0017106959],"genre_scores_gemma":[0.9980305,0.0008125832,0.00023434118,0.0004537548,0.00018573905,0.0000018505743,0.000016838552,0.0000111932195,0.00025320787],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991154,0.000027334738,0.00020719932,0.00030323226,0.00008180994,0.00026500662],"domain_scores_gemma":[0.9993675,0.00004920693,0.0000969319,0.000146567,0.000057559348,0.00028223355],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028186076,0.00017921202,0.00020620902,0.000036062575,0.00013409392,0.000018496274,0.00013522751,0.00018347379,0.000041633215],"category_scores_gemma":[0.0000064413016,0.00016727354,0.000047269277,0.00017858633,0.00023138164,0.00006243866,0.000084362706,0.00020120558,0.0000057841976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000102715065,0.0002754266,0.003109844,0.0002517914,0.000026452371,0.000012209049,0.00015205162,4.197941e-7,0.98718137,0.00019141211,0.00019705686,0.008499271],"study_design_scores_gemma":[0.00044339136,0.00014554067,0.00442399,0.00002843759,0.0000522608,0.000006185688,0.0001638917,0.0000378907,0.9903458,0.000114619535,0.0040298677,0.0002081256],"about_ca_topic_score_codex":0.0000063380176,"about_ca_topic_score_gemma":5.86281e-7,"teacher_disagreement_score":0.008291146,"about_ca_system_score_codex":0.000013667298,"about_ca_system_score_gemma":0.000020883308,"threshold_uncertainty_score":0.6821217},"labels":[],"label_agreement":null},{"id":"W2096892038","doi":"10.1021/bi500959t","title":"Quinone Reductase 2 Is an Adventitious Target of Protein Kinase CK2 Inhibitors TBBz (TBI) and DMAT","year":2014,"lang":"en","type":"article","venue":"Biochemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Chemistry; Quinone; Apoptosis; Biochemistry","score_opus":0.05311839308048297,"score_gpt":0.37210525196326855,"score_spread":0.31898685888278555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096892038","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961283,0.00077662966,0.000026912825,0.00033627226,0.00026138217,0.00018972,0.0001818548,0.00004326616,0.0020556438],"genre_scores_gemma":[0.99771893,0.00003820675,0.0004391452,0.0003726388,0.00035426396,0.000022121214,0.00008505719,0.000019386358,0.00095024926],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988607,0.000117145006,0.00026781196,0.00035744166,0.00012603207,0.0002708539],"domain_scores_gemma":[0.99924237,0.000026928728,0.0001618604,0.00023872669,0.000083150786,0.00024695823],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002884606,0.00020120046,0.00022833578,0.00003973991,0.00014039237,0.000017335366,0.00017225774,0.00026222976,0.0006699549],"category_scores_gemma":[0.000049373364,0.00020072174,0.000072065035,0.00009825156,0.00035399917,0.000079026075,0.00009014247,0.00028627733,0.000015949317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012510126,0.00047158744,0.004128502,0.00025472985,0.00005373521,0.000015445778,0.00012814673,9.368494e-7,0.9872339,0.000086841625,0.0059401244,0.0015609805],"study_design_scores_gemma":[0.00092929206,0.00012845763,0.0004635537,0.000045903547,0.00004569111,0.000019852143,0.000102089514,0.00020635851,0.9755457,0.00031542042,0.021974342,0.0002233074],"about_ca_topic_score_codex":0.000016810502,"about_ca_topic_score_gemma":8.010866e-7,"teacher_disagreement_score":0.016034218,"about_ca_system_score_codex":0.00002581415,"about_ca_system_score_gemma":0.000047341902,"threshold_uncertainty_score":0.8185195},"labels":[],"label_agreement":null},{"id":"W2099894699","doi":"10.1093/pcp/pcg057","title":"Molecular Cloning and Characterization of a cDNA Encoding a Novel Apoplastic Protein Preferentially Expressed in a Shikonin-Producing Callus Strain of Lithospermum erythrorhizon","year":2003,"lang":"en","type":"article","venue":"Plant and Cell Physiology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Nagoya City University; University of British Columbia","keywords":"Complementary DNA; cDNA library; Apoplast; Biochemistry; Pigment; Chemistry; Amino acid; Cell wall; Molecular biology; Peptide sequence; Callus; Biology; Gene; Botany","score_opus":0.05383428081415005,"score_gpt":0.3088417289315418,"score_spread":0.2550074481173918,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099894699","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986336,0.00014211165,0.0003252353,0.000019889698,0.00011714487,0.0003062839,0.00016308803,0.000008738156,0.00028388892],"genre_scores_gemma":[0.99951017,0.00012144256,0.00018423727,0.00003414131,0.000021470805,0.000019494433,0.00007524811,0.000010732474,0.000023076716],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888724,0.00021392074,0.00029719225,0.0003073696,0.00005822989,0.00023607256],"domain_scores_gemma":[0.99954516,0.00008492999,0.00019863015,0.00008106407,0.000033179782,0.000057045057],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002243013,0.00015702481,0.00032437476,0.00009365209,0.000055153476,0.0000061390247,0.00006761755,0.00014913894,0.00004190408],"category_scores_gemma":[0.00003111124,0.00014917343,0.000030232008,0.00009087619,0.00013161589,0.000059071874,0.000047111767,0.00023841164,4.110033e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028193253,0.0002806188,0.0032811328,0.00031729517,0.000037615155,0.000006341308,0.0008149936,0.000031837964,0.9934082,0.0013180741,0.0000012292543,0.00022070353],"study_design_scores_gemma":[0.0014697595,0.00019926118,0.03138737,0.000111568115,0.000043386877,0.000008430982,0.00009414453,0.0013928358,0.9647919,0.0001857296,0.00015176563,0.0001638349],"about_ca_topic_score_codex":0.000022866052,"about_ca_topic_score_gemma":0.000008123359,"teacher_disagreement_score":0.028616311,"about_ca_system_score_codex":0.000009911079,"about_ca_system_score_gemma":0.000040109582,"threshold_uncertainty_score":0.6083116},"labels":[],"label_agreement":null},{"id":"W2102815947","doi":"10.1183/09031936.00084211","title":"Plumbagin reverses proliferation and resistance to apoptosis in experimental PAH","year":2012,"lang":"en","type":"article","venue":"European Respiratory Journal","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"Canadian Institutes of Health Research; Université Laval","keywords":"Plumbagin; Medicine; Apoptosis; Resistance (ecology); Cancer research; Immunology; Genetics; Biology; Ecology","score_opus":0.14464923406175026,"score_gpt":0.41420971700009984,"score_spread":0.26956048293834955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2102815947","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9856198,0.0022609234,0.00003559592,0.0002863049,0.00078544393,0.00015511917,0.0000066648918,0.000016539967,0.010833654],"genre_scores_gemma":[0.99379385,0.00005608153,0.00034568767,0.0045192167,0.0008146986,0.0000053523718,0.0000010708304,0.000021491076,0.00044253736],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981041,0.0009948554,0.00027931973,0.00016091185,0.000120637225,0.0003401906],"domain_scores_gemma":[0.99939895,0.00003531983,0.00009841942,0.00008431549,0.000037435475,0.00034557766],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013500969,0.00013804971,0.0001331963,0.0001299614,0.00027171377,0.000058294754,0.00012957252,0.0000476015,0.0002770514],"category_scores_gemma":[0.00005140867,0.00012976573,0.000035690577,0.00012029124,0.00007046444,0.0002836134,0.00007528413,0.00048093832,0.00010607247],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000602976,0.0006506399,0.51544565,0.00002585567,0.00006151489,0.00012843899,0.0037627867,0.000013547075,0.4137985,0.00049590104,0.06070784,0.004306343],"study_design_scores_gemma":[0.0015490232,0.00015244447,0.17483352,0.000052435804,0.000019654766,0.000044079356,0.00053273153,0.000004926304,0.10337537,0.000015427831,0.71914077,0.00027962963],"about_ca_topic_score_codex":4.911006e-7,"about_ca_topic_score_gemma":0.0000032719743,"teacher_disagreement_score":0.6584329,"about_ca_system_score_codex":0.000079459685,"about_ca_system_score_gemma":0.000023540428,"threshold_uncertainty_score":0.52916926},"labels":[],"label_agreement":null},{"id":"W2105546486","doi":"10.1128/iai.68.9.5462-5465.2000","title":"Role of Inducible Nitric Oxide Synthase in Resistance to<i>Mycobacterium leprae</i>in Mice","year":2000,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Thomas Hospital","funders":"","keywords":"Mycobacterium leprae; Leprosy; Nitric oxide synthase; Biology; Immunity; Nitric oxide; Microbiology; Immunology; Mycobacterium; Bacteria; Immune system; Genetics","score_opus":0.05422806203598708,"score_gpt":0.3700707771236951,"score_spread":0.31584271508770806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2105546486","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9889781,0.000468012,0.0000035170206,0.00010106659,0.00010946058,0.00017805275,0.000014303073,0.000019106297,0.010128381],"genre_scores_gemma":[0.99820817,0.0008110507,0.000031230134,0.0003367099,0.000020967542,0.000016651682,0.0000056304825,0.0000072778294,0.00056231493],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9989617,0.00036478086,0.0002548691,0.00016566679,0.000052318395,0.0002006895],"domain_scores_gemma":[0.9996082,0.00010558337,0.000056623125,0.000116263094,0.000036051704,0.000077273246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045357263,0.00011279528,0.00018550752,0.0002021452,0.00009791142,0.000011292707,0.000079620564,0.00013774872,0.00079149957],"category_scores_gemma":[0.000047151007,0.000119688426,0.000033518365,0.0004897622,0.00007644264,0.00013548008,0.000035212855,0.00048169662,0.000036265585],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00059583934,0.0007401968,0.4282772,0.00004708824,0.000022056753,0.000006951708,0.00040784312,0.00006629684,0.557149,0.000089738154,0.00023235272,0.012365447],"study_design_scores_gemma":[0.0008927208,0.00004805259,0.8414256,0.000041774732,0.000012134046,0.0000066803436,0.000083158426,0.0000752644,0.10301573,0.00017156957,0.054095253,0.00013204079],"about_ca_topic_score_codex":0.0014387226,"about_ca_topic_score_gemma":0.0008164192,"teacher_disagreement_score":0.45413327,"about_ca_system_score_codex":0.000050699156,"about_ca_system_score_gemma":0.000027087654,"threshold_uncertainty_score":0.8666366},"labels":[],"label_agreement":null},{"id":"W2110016973","doi":"10.1039/c4ce00328d","title":"Rapid and facile solvent-free mechanosynthesis in a cell lysis mill: preparation and mechanochemical complexation of aminobenzoquinones","year":2014,"lang":"en","type":"article","venue":"CrystEngComm","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Concordia University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Mechanosynthesis; Lysis; Ball mill; Solvent; Chemistry; Chemical engineering; Mechanochemistry; Reagent; Materials science; Organic chemistry; Metallurgy; Biochemistry","score_opus":0.08125827100826279,"score_gpt":0.3578709485037895,"score_spread":0.2766126774955267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110016973","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965228,0.00070077315,0.0008788154,0.00024272688,0.0001251642,0.0002454418,0.00004481916,0.000024613135,0.0012148711],"genre_scores_gemma":[0.9987246,0.00029386574,0.0006761032,0.00014528095,0.000041437957,0.000025391737,0.000022827504,0.000010922275,0.000059583548],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987739,0.000354235,0.00030401815,0.0002683633,0.00010155222,0.00019793377],"domain_scores_gemma":[0.99918336,0.00032305912,0.00015285527,0.0001940075,0.00005540729,0.00009132748],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048727755,0.0001580303,0.00030363,0.0001250036,0.00010369136,0.000015868778,0.00015112676,0.00018549638,0.00013038318],"category_scores_gemma":[0.00008798861,0.00015174721,0.00004847639,0.00011295827,0.00013010472,0.0000939705,0.00013702692,0.00017724159,0.000003226078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003000785,0.00035824633,0.014665995,0.00026927813,0.000060400856,0.0000026938872,0.001003961,0.000017128483,0.97138685,0.0013544407,0.00079198653,0.009788942],"study_design_scores_gemma":[0.004015285,0.00043970274,0.01570266,0.00007993447,0.00023157889,0.000018695468,0.0006233805,0.053567726,0.90598935,0.0037570545,0.015112057,0.00046257325],"about_ca_topic_score_codex":0.0000324542,"about_ca_topic_score_gemma":0.000046951656,"teacher_disagreement_score":0.0653975,"about_ca_system_score_codex":0.000020881116,"about_ca_system_score_gemma":0.000012923395,"threshold_uncertainty_score":0.6188072},"labels":[],"label_agreement":null},{"id":"W2110961018","doi":"10.1089/dna.2008.0735","title":"DNA Adducts with Antioxidant Flavonoids: Morin, Apigenin, and Naringin","year":2008,"lang":"en","type":"article","venue":"DNA and Cell Biology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Morin; Naringin; Apigenin; DNA; Binding constant; Flavonoid; Polyphenol; Luteolin; Biology; Biochemistry; Fisetin; Chemistry; Antioxidant; Binding site; Chromatography","score_opus":0.07387883988888011,"score_gpt":0.34318183758538434,"score_spread":0.26930299769650423,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110961018","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98985106,0.0027528116,0.000052334104,0.0002186717,0.00041223544,0.00017405907,0.00003218989,0.00005321744,0.006453413],"genre_scores_gemma":[0.99441415,0.00312123,0.00015113922,0.0007838672,0.00017402813,0.000014207345,0.000022314736,0.000016356662,0.0013026948],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880004,0.00015420122,0.00017966446,0.00041442705,0.000046187484,0.0004054848],"domain_scores_gemma":[0.9994656,0.0000834602,0.00008232359,0.0001242089,0.00004787172,0.00019653662],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014670924,0.00022937241,0.00027786827,0.000076840915,0.00037828978,0.000010993917,0.00011362576,0.00024174666,0.00022020403],"category_scores_gemma":[0.000006628023,0.0001777604,0.00003507751,0.00009176109,0.0006734056,0.00006279754,0.00009502711,0.0003317032,0.00003950134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003221076,0.00024409726,0.14204589,0.000050654628,0.00012721958,0.00019721704,0.0006222149,0.0000024694093,0.8480457,0.0012209583,0.0014737379,0.0056477524],"study_design_scores_gemma":[0.004148358,0.001254216,0.08678509,0.00001779792,0.00015504999,0.0005694995,0.0003324936,0.00026242173,0.53613853,0.00035948146,0.36918956,0.0007874591],"about_ca_topic_score_codex":0.000024355937,"about_ca_topic_score_gemma":0.000009663036,"teacher_disagreement_score":0.36771584,"about_ca_system_score_codex":0.00001213691,"about_ca_system_score_gemma":0.000037756596,"threshold_uncertainty_score":0.72488594},"labels":[],"label_agreement":null},{"id":"W2114005603","doi":"10.1016/j.cbi.2007.02.011","title":"Molecular cytotoxic mechanisms of catecholic polychlorinated biphenyl metabolites in isolated rat hepatocytes","year":2007,"lang":"en","type":"article","venue":"Chemico-Biological Interactions","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Environmental Health Sciences","keywords":"Chemistry; Cytotoxicity; Uridine diphosphate; Glucuronidation; Cytotoxic T cell; Metabolite; Biochemistry; Biphenyl; Catechol; Polychlorinated biphenyl; Stereochemistry; Microsome; In vitro; Organic chemistry; Enzyme","score_opus":0.12032907829461852,"score_gpt":0.4251875774150037,"score_spread":0.30485849912038515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114005603","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992794,0.00042869768,0.0025593138,0.00020093139,0.0008854418,0.00032587413,0.0000470453,0.00011450966,0.0026442152],"genre_scores_gemma":[0.9984859,0.00016532249,0.00029128062,0.00064987957,0.000059736656,0.000041620922,0.000085552,0.00001906147,0.0002016471],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99823713,0.00015493439,0.0005549595,0.00041330306,0.000096525415,0.00054311584],"domain_scores_gemma":[0.9988568,0.00040351745,0.00022549626,0.00020302631,0.00012488697,0.00018628893],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00046320708,0.0002882245,0.00043814533,0.0002503343,0.00011146997,0.000015021384,0.00033074492,0.0003963789,0.0012502369],"category_scores_gemma":[0.00015443098,0.00024257542,0.00019851116,0.00055541645,0.00025875994,0.00012786155,0.00013492182,0.00093341654,0.000059187292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042651352,0.00069543597,0.00905254,0.000013661203,0.00011805574,0.00007327726,0.000081393286,0.00001524533,0.98515284,0.0036653038,0.00010933615,0.00059639825],"study_design_scores_gemma":[0.0008044303,0.00012930916,0.002779286,0.00002372465,0.000047287373,0.000050510935,0.00017420662,0.00057822204,0.9838572,0.0018506069,0.009447274,0.00025790549],"about_ca_topic_score_codex":0.00005095479,"about_ca_topic_score_gemma":0.000019955089,"teacher_disagreement_score":0.009337937,"about_ca_system_score_codex":0.00009283369,"about_ca_system_score_gemma":0.000024613848,"threshold_uncertainty_score":0.99966276},"labels":[],"label_agreement":null},{"id":"W2125465637","doi":"10.1021/jo701435p","title":"Total Synthesis of Streptonigrone","year":2007,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Total synthesis; Quinoline; Sequence (biology); Combinatorial chemistry; Surface modification; Key (lock); Stereochemistry; Organic chemistry; Biochemistry; Computer science","score_opus":0.05438509649721856,"score_gpt":0.37834042825278125,"score_spread":0.3239553317555627,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125465637","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945667,0.00059078523,0.00018953333,0.00030922474,0.00028182135,0.000029989493,0.000007303413,0.0000057614325,0.004018886],"genre_scores_gemma":[0.9989611,0.0001986813,0.000067970606,0.00007605168,0.00030819222,1.418438e-7,4.188534e-7,0.0000103182965,0.00037710465],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912953,0.00006492648,0.00040289058,0.000057286186,0.00016170688,0.00018365151],"domain_scores_gemma":[0.9987273,0.00048036332,0.00043179805,0.00012139914,0.00013482392,0.00010427995],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0013156518,0.00010029067,0.00020501933,0.000021868444,0.000080023754,0.0000039749007,0.0003072031,0.000119070995,0.0041578356],"category_scores_gemma":[0.00014295358,0.00006807618,0.00010131759,0.00012980755,0.00018234646,0.000041135252,0.000057012945,0.00049282855,0.000008745157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029774976,0.00019841532,0.0038351647,0.000038495382,0.00019766096,0.00003168204,0.00017573789,0.000008825612,0.99111015,0.0000050839535,0.0010697398,0.0030312943],"study_design_scores_gemma":[0.0004172643,0.00003668657,0.0054857032,0.000023656525,0.00019104063,0.00052804104,0.0005258993,0.000012088131,0.99068415,0.000034608052,0.0019903819,0.000070502334],"about_ca_topic_score_codex":0.0000015350771,"about_ca_topic_score_gemma":8.8042646e-7,"teacher_disagreement_score":0.004394425,"about_ca_system_score_codex":0.0000472289,"about_ca_system_score_gemma":0.00007518698,"threshold_uncertainty_score":0.9967525},"labels":[],"label_agreement":null},{"id":"W2134071192","doi":"10.1139/v09-070","title":"Studies on chemo- and diastereo-selectivity of the Diels–Alder reactions of sulfinyltoluquinones with cyclopentadiene","year":2009,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Cyclopentadiene; Chemistry; Cycloaddition; Adduct; Selectivity; Catalysis; Diels–Alder reaction; Double bond; Organic chemistry; Medicinal chemistry","score_opus":0.08995445314155866,"score_gpt":0.37664209623035144,"score_spread":0.2866876430887928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134071192","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952421,0.0008547374,0.0000019572387,0.0010636097,0.00019398618,0.000052968935,0.000022683107,0.0000014390058,0.002566524],"genre_scores_gemma":[0.9991875,0.00011168534,0.000019516508,0.00022895142,0.000078969155,6.6967226e-7,5.010358e-7,0.0000050143303,0.000367141],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993631,0.00004996528,0.00025311587,0.0000896232,0.00008464069,0.00015950805],"domain_scores_gemma":[0.9990527,0.00009379193,0.0003547814,0.00009771865,0.00019932634,0.00020165209],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020086448,0.000107642605,0.00024346322,0.000038581795,0.00012651396,0.0000061352202,0.00015390053,0.00007809889,0.00006611543],"category_scores_gemma":[0.00008451581,0.00007197883,0.000064477645,0.00012300794,0.00035629998,0.000055312044,0.000010369568,0.00036335026,2.320182e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00057075644,0.00040961397,0.19797382,0.00029812832,0.0009875294,0.00013520842,0.0024010239,0.00017854129,0.78717875,0.00016858925,0.003316375,0.0063816365],"study_design_scores_gemma":[0.0008555323,0.0002153928,0.07182723,0.00019184004,0.000121997895,0.0003134828,0.0006612993,0.0000068890845,0.92148775,0.00016573808,0.0040431833,0.00010968752],"about_ca_topic_score_codex":0.00006406585,"about_ca_topic_score_gemma":0.00048686637,"teacher_disagreement_score":0.13430893,"about_ca_system_score_codex":0.000061460174,"about_ca_system_score_gemma":0.00028139201,"threshold_uncertainty_score":0.29352117},"labels":[],"label_agreement":null},{"id":"W2141287168","doi":"10.1002/adsc.200505248","title":"Synthesis of Aryl‐Substituted 1,4‐Benzoquinone <i>via</i> Water‐Promoted and In(OTf)<sub>3</sub>‐Catalyzed <i>in situ</i> Conjugate Addition‐Dehydrogenation of Aromatic Compounds to 1,4‐Benzoquinone in Water","year":2006,"lang":"en","type":"article","venue":"Advanced Synthesis & Catalysis","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Chemistry; Dehydrogenation; Regioselectivity; Catalysis; Conjugate; Nucleophile; Aryl; Medicinal chemistry; Quinone; In situ; 1,4-Benzoquinone; Benzoquinone; Nucleophilic addition; Organic chemistry; Alkyl","score_opus":0.02112138670805138,"score_gpt":0.29750200995963977,"score_spread":0.2763806232515884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141287168","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99766594,0.00030157415,0.00018565432,0.00034438603,0.00014519077,0.00078288966,0.00021851709,0.000049577415,0.00030624395],"genre_scores_gemma":[0.9983658,0.0002327946,0.0003640649,0.00010714269,0.00003597424,0.0003429809,0.00048573225,0.00005499369,0.000010496977],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99611515,0.0003424429,0.0015542079,0.00080155506,0.00036608215,0.0008205617],"domain_scores_gemma":[0.9979205,0.00094734493,0.00035434435,0.000471731,0.00013005629,0.00017603894],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010761883,0.000531997,0.0013517352,0.0011596632,0.00013260136,0.00002239894,0.00040026347,0.00033807216,0.000084413245],"category_scores_gemma":[0.00017713483,0.00046218024,0.00020988505,0.0009819202,0.00038526006,0.00048217422,0.0001763694,0.000382692,0.000050144678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00077005225,0.001432858,0.0068240324,0.00023580198,0.00020071992,0.000096530544,0.0004174779,0.0027676143,0.9819689,0.000018491524,0.000025746087,0.0052417987],"study_design_scores_gemma":[0.0016000407,0.00004888206,0.013942245,0.00032810398,0.00032226153,0.000019797462,0.00011654731,0.0008886941,0.9815515,0.00055547914,0.00009569819,0.0005307369],"about_ca_topic_score_codex":0.00041243472,"about_ca_topic_score_gemma":0.0026103975,"teacher_disagreement_score":0.007118213,"about_ca_system_score_codex":0.0002074957,"about_ca_system_score_gemma":0.00003944142,"threshold_uncertainty_score":0.999783},"labels":[],"label_agreement":null},{"id":"W2149263297","doi":"10.1039/c5ob02100f","title":"2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition","year":2015,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Chemistry; Hsp90; Heat shock protein; Tubulin; Hsp90 inhibitor; Biochemistry; Cell biology; Microtubule","score_opus":0.06509029212372049,"score_gpt":0.369466096866853,"score_spread":0.3043758047431325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149263297","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9920465,0.0014802046,0.0020300888,0.0013886245,0.00029019214,0.00036754424,0.000040699615,0.00010113587,0.0022550432],"genre_scores_gemma":[0.997287,0.00020367504,0.00012565576,0.0010857793,0.00026866546,0.000031817348,0.000102285645,0.000048128117,0.0008470054],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99825156,0.00012261755,0.00032163667,0.0005505053,0.00028005958,0.0004736349],"domain_scores_gemma":[0.99903744,0.000017317014,0.00009617738,0.0002496844,0.00013616944,0.0004631915],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028861946,0.00033289904,0.00028475033,0.000040442814,0.00023184504,0.00006443263,0.00018716301,0.00034669432,0.0008539988],"category_scores_gemma":[0.000084884785,0.00032508024,0.00009052807,0.00023711182,0.00025065005,0.00011071439,0.0002390311,0.00044863386,0.00015028351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015198,0.00027492116,0.0018017098,0.00013125922,0.00012031697,0.000335642,0.00014049231,0.0000014855107,0.99515796,0.000024427214,0.00118069,0.0006791022],"study_design_scores_gemma":[0.0019117552,0.00007902996,0.0004337062,0.00008467732,0.000112076596,0.0002495641,0.00018608331,0.00045543571,0.98367953,0.00015607198,0.01225688,0.00039520185],"about_ca_topic_score_codex":0.000027831993,"about_ca_topic_score_gemma":0.000002037035,"teacher_disagreement_score":0.011478456,"about_ca_system_score_codex":0.00014656204,"about_ca_system_score_gemma":0.00014805456,"threshold_uncertainty_score":0.9999201},"labels":[],"label_agreement":null},{"id":"W2151663541","doi":"10.1139/cjpp-2014-0464","title":"Shikonin inhibits TNF-α-induced growth and invasion of rat aortic vascular smooth muscle cells","year":2015,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Apoptosis; Vascular smooth muscle; Cyclin D1; Tumor necrosis factor alpha; Cell growth; Cell cycle; Cancer research; Protein kinase B; Biology; Cell biology; Chemistry; Pharmacology; Endocrinology; Biochemistry; Smooth muscle","score_opus":0.09481311645342887,"score_gpt":0.35174450192788326,"score_spread":0.2569313854744544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151663541","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99346036,0.0020922222,0.000012485817,0.00067510287,0.0032353809,0.00018854858,0.00002338329,0.0000067850438,0.00030572063],"genre_scores_gemma":[0.9970229,0.0006731284,0.000088703535,0.00180567,0.00035148964,0.000004476494,0.000005818527,0.00001936036,0.000028445416],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978456,0.000779288,0.0005188563,0.00027086507,0.000095562435,0.0004898166],"domain_scores_gemma":[0.99782896,0.00024364846,0.0003992216,0.00009221451,0.00029565176,0.0011403162],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00073887495,0.00024866575,0.00057358894,0.00032392287,0.00020983601,0.00001106507,0.0002477491,0.00037552,0.00060892757],"category_scores_gemma":[0.00006477282,0.00022390345,0.00011015818,0.00019620179,0.00070750277,0.00017851157,0.000066443296,0.0008008775,0.0000081829885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021851654,0.00010408603,0.0033950403,0.000108303626,0.00022057806,0.000102476486,0.00085807306,0.000028881987,0.98738754,0.00020330465,0.0048933923,0.002479809],"study_design_scores_gemma":[0.004804395,0.0011490883,0.0157845,0.000036625293,0.0004561686,0.0000779611,0.00031792422,0.00028180494,0.9576586,0.0016845397,0.017400956,0.00034746746],"about_ca_topic_score_codex":0.00040577792,"about_ca_topic_score_gemma":0.0002502089,"teacher_disagreement_score":0.02972897,"about_ca_system_score_codex":0.000056278965,"about_ca_system_score_gemma":0.00076032523,"threshold_uncertainty_score":0.9130517},"labels":[],"label_agreement":null},{"id":"W2154150745","doi":"10.1073/pnas.0803171105","title":"Interferon regulatory factor 4 differentially regulates the production of Th2 cytokines in naïve vs. effector/memory CD4 <sup>+</sup> T cells","year":2008,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Effector; Cytokine; Biology; IL-2 receptor; Interleukin 21; Cell biology; Gene knockdown; T cell; Molecular biology; Immunology; Cell culture; Immune system","score_opus":0.10501790939294797,"score_gpt":0.36885052061496454,"score_spread":0.26383261122201657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2154150745","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99705863,0.00017526021,2.0755826e-7,0.0016485056,0.0001767262,0.00035259416,0.00002347689,0.0000114712075,0.0005531572],"genre_scores_gemma":[0.9991242,0.00011068261,0.000059792153,0.0001693434,0.00015680336,0.000012186839,3.2876028e-7,0.000006242158,0.00036040047],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99839336,0.00006427445,0.00042530388,0.0002861157,0.00063284993,0.00019811052],"domain_scores_gemma":[0.99893916,0.00025528524,0.0005011642,0.000018263014,0.00025102342,0.00003508567],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010839815,0.00015118929,0.00024643747,0.00018371885,0.00028513488,0.000010092592,0.0007883453,0.00015496064,0.0000584512],"category_scores_gemma":[0.00024295546,0.00008888696,0.00011352799,0.0005308907,0.0021510245,0.0002946784,0.0001699429,0.0003960959,0.0000018338861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020830249,0.0002022223,0.05310259,0.000127381,0.000047612637,3.5103998e-8,0.0010925748,0.0004728536,0.94180447,0.00095994625,0.0016238538,0.0003581812],"study_design_scores_gemma":[0.00022743648,0.00007764772,0.2708567,0.000080417,0.000017971066,0.000008457708,0.00012669197,0.00087698933,0.72649586,0.0009620998,0.00019612038,0.00007360113],"about_ca_topic_score_codex":0.000008183193,"about_ca_topic_score_gemma":2.2027383e-7,"teacher_disagreement_score":0.21775411,"about_ca_system_score_codex":0.000046256737,"about_ca_system_score_gemma":0.000043476186,"threshold_uncertainty_score":0.79255396},"labels":[],"label_agreement":null},{"id":"W2154353832","doi":"10.1002/ptr.906","title":"Isolation of an antimicrobial compound from <i>Impatiens balsamina</i> L. using bioassay‐guided fractionation","year":2001,"lang":"en","type":"article","venue":"Phytotherapy Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Western University","funders":"","keywords":"Brine shrimp; Artemia salina; Antimicrobial; Fractionation; Bioassay; Pharmacognosy; Chromatography; Bioactive compound; Impatiens; Biology; Bacteria; Chemistry; Traditional medicine; Botany; Microbiology; Biological activity; Organic chemistry; Toxicity; Biochemistry; In vitro","score_opus":0.4354282630916434,"score_gpt":0.550773071673836,"score_spread":0.11534480858219265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2154353832","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99475145,0.00020004844,0.0018108244,0.00033865217,0.0006121075,0.00037643456,0.00015529114,0.0000388339,0.0017163616],"genre_scores_gemma":[0.99639237,0.00048014385,0.0018395607,0.00037806193,0.0005330617,0.000010281503,0.00013951563,0.00003101044,0.00019597702],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974561,0.0010166054,0.00035418355,0.0003560711,0.0003888005,0.00042828458],"domain_scores_gemma":[0.9985759,0.00037528982,0.00016442678,0.00023014014,0.00051317504,0.00014106132],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001071893,0.00016291795,0.00024204091,0.00027565274,0.00045655278,0.000047150974,0.00026687531,0.00022395769,0.0014009209],"category_scores_gemma":[0.000037983074,0.00016447373,0.00007907021,0.00054267497,0.0003398433,0.00037872585,0.000048531027,0.00056936336,0.00003564298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007754271,0.00092983,0.047500603,0.00001297968,0.00011083329,0.000015157761,0.00040663453,0.00031316135,0.93961734,0.00012648485,0.0017671821,0.008424343],"study_design_scores_gemma":[0.0061886734,0.0008602406,0.0918966,0.000086688284,0.000072116396,0.000060113187,0.00047320424,0.13391457,0.66711855,0.0028357948,0.09583629,0.0006571379],"about_ca_topic_score_codex":0.0007328674,"about_ca_topic_score_gemma":0.00008460803,"teacher_disagreement_score":0.27249882,"about_ca_system_score_codex":0.00013471072,"about_ca_system_score_gemma":0.00010602154,"threshold_uncertainty_score":0.99951196},"labels":[],"label_agreement":null},{"id":"W2158182233","doi":"10.1093/toxsci/kfh182","title":"Application of Quantitative Structure-Toxicity Relationships for the Comparison of the Cytotoxicity of 14 p-Benzoquinone Congeners in Primary Cultured Rat Hepatocytes Versus PC12 Cells","year":2004,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cytotoxicity; Glutathione; Chemistry; Benzoquinone; Reactive oxygen species; Cytotoxic T cell; Hepatocyte; Quinone; Toxicity; Biochemistry; Hydrogen peroxide; In vitro; Enzyme; Organic chemistry","score_opus":0.2838262276235889,"score_gpt":0.45769474730183857,"score_spread":0.17386851967824968,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158182233","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99567014,0.00041355996,0.0013419694,0.000525618,0.0004692053,0.0010784445,0.00012337868,0.000010496288,0.00036717692],"genre_scores_gemma":[0.99804753,0.00004302256,0.0016876674,0.00013403728,0.000023673741,0.000044355995,0.000005734069,0.0000036419165,0.000010338183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982116,0.0004442259,0.0005379741,0.00027819403,0.0002753089,0.00025265582],"domain_scores_gemma":[0.99720156,0.001882513,0.00057193206,0.00014955187,0.00014273927,0.000051694133],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010779065,0.00015299719,0.00037981503,0.000050070532,0.0004181375,0.00000938366,0.00065265474,0.00023392348,0.0000466826],"category_scores_gemma":[0.000315035,0.00008191486,0.0001342699,0.0006146059,0.0023768272,0.00009285232,0.00011879187,0.0003868005,0.000001023999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007310189,0.000647712,0.08149682,0.000041832256,0.00004943405,2.2002946e-7,0.00074252806,0.018029748,0.87934554,0.018437669,0.00008234929,0.00039510487],"study_design_scores_gemma":[0.0015305809,0.0006454437,0.12398402,0.000014153788,0.000066742294,5.4060985e-7,0.0008288846,0.004607289,0.8657157,0.0022947693,0.0001997373,0.00011216473],"about_ca_topic_score_codex":0.00004345018,"about_ca_topic_score_gemma":0.0003108657,"teacher_disagreement_score":0.042487193,"about_ca_system_score_codex":0.00009320203,"about_ca_system_score_gemma":0.0001254554,"threshold_uncertainty_score":0.8757519},"labels":[],"label_agreement":null},{"id":"W2164754292","doi":"10.1002/jcb.20064","title":"Ryanodine receptor signaling is required for anti‐CD3‐induced T cell proliferation, interleukin‐2 synthesis, and interleukin‐2 receptor signaling","year":2004,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Ryanodine receptor; Cell biology; Cell growth; T cell; Receptor; Signal transduction; Biology; Interleukin 2; Dantrolene; IL-2 receptor; Chemistry; Endocrinology; Intracellular; Internal medicine; Immunology; Biochemistry; Calcium; Immune system; Medicine","score_opus":0.06814528733785223,"score_gpt":0.35510177913445434,"score_spread":0.2869564917966021,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2164754292","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928051,0.0015658427,0.0026174972,0.001387158,0.0010556477,0.00029811013,0.00008449608,0.000027208576,0.00015892141],"genre_scores_gemma":[0.9944391,0.00026595424,0.0029850316,0.0006341865,0.0012498157,0.00001833647,0.000032258577,0.00005130595,0.00032399385],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978108,0.0001349276,0.00094237796,0.0004011228,0.00026811674,0.00044266344],"domain_scores_gemma":[0.99785155,0.00022955755,0.00087155146,0.00018383151,0.0005224478,0.00034107943],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010158657,0.0003773465,0.00055987574,0.00014623937,0.0003104503,0.00011019718,0.00039669,0.0004635022,0.0005153817],"category_scores_gemma":[0.0002150583,0.0003479722,0.0003160224,0.00016990602,0.00016544864,0.00021023511,0.00008496531,0.00072599197,0.000015279551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00062088756,0.00041320658,0.00052248914,0.00030714428,0.00028143128,0.000031192525,0.00053095934,0.00003498496,0.9932543,0.000015485764,0.0030095917,0.0009783406],"study_design_scores_gemma":[0.0024719723,0.0003093579,0.000008405854,0.0003228687,0.0002092775,0.000077071934,0.00047530045,0.00008757342,0.9868086,0.00014257741,0.008713322,0.00037366783],"about_ca_topic_score_codex":0.0000028196378,"about_ca_topic_score_gemma":2.922429e-7,"teacher_disagreement_score":0.006445681,"about_ca_system_score_codex":0.00020825426,"about_ca_system_score_gemma":0.00027533734,"threshold_uncertainty_score":0.99989724},"labels":[],"label_agreement":null},{"id":"W2167995914","doi":"10.3233/spe-2009-0368","title":"Structural analysis of DNA and RNA interactions with antioxidant flavonoids","year":2009,"lang":"en","type":"article","venue":"","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"","keywords":"Chemistry; Delphinidin; DNA; Kaempferol; Apigenin; RNA; Flavonoid; Antioxidant; Stereochemistry; Biochemistry; Naringin; Cyanidin; Chromatography","score_opus":0.08289936099426008,"score_gpt":0.41956331691724164,"score_spread":0.33666395592298154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167995914","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98982775,0.000076061144,0.00023388187,0.00044819302,0.00014007956,0.0000782818,0.000026000453,0.000027060865,0.009142677],"genre_scores_gemma":[0.9983669,0.00005115119,0.00031014608,0.0005866908,0.00003506338,0.0000013123805,0.000010704845,0.000003730195,0.0006342927],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9993657,0.00006671056,0.00017072985,0.00017279135,0.00006825595,0.0001558511],"domain_scores_gemma":[0.99960184,0.000059980855,0.00008606497,0.000095562784,0.00006599318,0.00009057139],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008696432,0.0001138258,0.00023629563,0.0001983404,0.00011737469,0.0000135864475,0.00007940234,0.000054919776,0.0010102339],"category_scores_gemma":[0.0000055166456,0.00008135078,0.00007345906,0.00041393324,0.00013265568,0.00011004059,0.0000193249,0.0001901094,0.000002924935],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005871948,0.00034358064,0.18119927,0.000018675519,0.0037222358,0.000035585777,0.0006626199,0.00035953682,0.771072,0.008220305,0.0010763558,0.03270266],"study_design_scores_gemma":[0.0009785204,0.00032531854,0.87467295,0.000008469745,0.001914256,0.000020762038,0.00024153286,0.015252498,0.10283374,0.00021466063,0.0033026824,0.00023463416],"about_ca_topic_score_codex":0.000021238211,"about_ca_topic_score_gemma":0.000066858076,"teacher_disagreement_score":0.69347364,"about_ca_system_score_codex":0.000013233484,"about_ca_system_score_gemma":0.000013910851,"threshold_uncertainty_score":0.99990296},"labels":[],"label_agreement":null},{"id":"W2170080049","doi":"10.1139/o06-087","title":"Aminonaphthoquinone induces oxidative stress in <i>Staphylococcus aureus</i>","year":2006,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Universidade Federal do Rio Grande do Sul","keywords":"Staphylococcus aureus; Chemistry; Salicylhydroxamic acid; Reactive oxygen species; Thiobarbituric acid; Oxidative stress; Biochemistry; Lipid peroxidation; Naphthoquinone; Antimycin A; Scavenger; Antioxidant; Bacteria; Mitochondrion; Biology; Organic chemistry; Enzyme","score_opus":0.04327624738549756,"score_gpt":0.3489713294574314,"score_spread":0.30569508207193385,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2170080049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9711001,0.0031511486,0.000010629003,0.00017362233,0.0002537802,0.00013098078,0.00018639877,0.000031718497,0.024961654],"genre_scores_gemma":[0.99753857,0.0002790299,0.00006402824,0.00032507873,0.00028305917,0.000025613215,0.00019011417,0.000010238383,0.0012842661],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986992,0.00015317467,0.00026214318,0.00043503402,0.00004610894,0.00040437962],"domain_scores_gemma":[0.99949133,0.00012445723,0.000114463575,0.0001308017,0.000037662514,0.00010127843],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018128852,0.00023194693,0.00024382814,0.000058310237,0.00012725726,0.000014263208,0.00018725521,0.00048211688,0.00025918335],"category_scores_gemma":[0.0000106956695,0.00021351535,0.000051608975,0.00014524235,0.00041706488,0.000041141036,0.000106495136,0.00043653708,0.000015906446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000089083296,0.00041739413,0.07514059,0.000050430444,0.000019721987,0.0000355567,0.000038887687,0.0000044099993,0.92139935,0.0002480564,0.0010788452,0.0014776601],"study_design_scores_gemma":[0.0010251383,0.00007223773,0.006541743,0.000010960302,0.00001981367,0.000004615407,0.00015500946,0.000026558962,0.9634654,0.00035847165,0.028065851,0.00025422827],"about_ca_topic_score_codex":0.000089596644,"about_ca_topic_score_gemma":0.000020632371,"teacher_disagreement_score":0.06859885,"about_ca_system_score_codex":0.000030010928,"about_ca_system_score_gemma":0.000039666018,"threshold_uncertainty_score":0.87069035},"labels":[],"label_agreement":null},{"id":"W2180086034","doi":"10.1159/000441727","title":"The Small Molecule Indirubin-3'-Oxime Inhibits Protein Kinase R: Antiapoptotic and Antioxidant Effect in Rat Cardiac Myocytes","year":2015,"lang":"en","type":"article","venue":"Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Indirubin; Antioxidant; Myocyte; Chemistry; Protein kinase A; Kinase; Pharmacology; Protein kinase C; Small molecule; Oxime; Cardiac myocyte; Cell biology; Biochemistry; Medicine; Biology","score_opus":0.08172550162689081,"score_gpt":0.38600532770392953,"score_spread":0.30427982607703874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2180086034","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.986158,0.0065185516,0.000011426405,0.0015869798,0.0026359728,0.0014945999,0.000026545133,0.00009006615,0.0014778252],"genre_scores_gemma":[0.9967246,0.0006586099,0.000052146086,0.0012380843,0.00032021274,0.00027489415,0.000012490993,0.0000416909,0.0006772378],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9958083,0.002086807,0.0004582359,0.0005668497,0.00018241176,0.00089736574],"domain_scores_gemma":[0.9984461,0.0006126786,0.00018695161,0.00019398845,0.00011959236,0.000440681],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0019939686,0.00041467798,0.00053684006,0.00018876135,0.00039439418,0.00006520231,0.00038539703,0.0003086414,0.00010341411],"category_scores_gemma":[0.00014655326,0.00031745498,0.000118673845,0.0003950948,0.00064821955,0.00013866773,0.00034151378,0.0010536454,0.0001621044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014701737,0.00043205215,0.045759354,0.00009412641,0.00029891412,0.00035282937,0.00039099017,0.00003689494,0.9332827,0.00047675238,0.010096613,0.007308598],"study_design_scores_gemma":[0.0057346937,0.00063526584,0.005303221,0.000029412047,0.00022438921,0.000033187072,0.000119890006,0.0011668836,0.9294682,0.00029526593,0.056515526,0.0004740757],"about_ca_topic_score_codex":0.00005795858,"about_ca_topic_score_gemma":0.000028276501,"teacher_disagreement_score":0.046418913,"about_ca_system_score_codex":0.00013412964,"about_ca_system_score_gemma":0.00015944395,"threshold_uncertainty_score":0.99992776},"labels":[],"label_agreement":null},{"id":"W2181294473","doi":"10.7164/antibiotics.55.1072","title":"Chloroquinocin, a Novel Chlorinated Naphthoquinone Antibiotic from Streptomyces sp., LL-A9227.","year":2002,"lang":"en","type":"article","venue":"The Journal of Antibiotics","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Streptomyces; Naphthoquinone; Antibiotics; Microbiology; Chemistry; Beta-lactam; Biology; Bacteria; Organic chemistry; Genetics","score_opus":0.16070467200278518,"score_gpt":0.3842893016214175,"score_spread":0.22358462961863232,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2181294473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99007404,0.002436516,0.00033209423,0.0016973029,0.0027286739,0.00019130694,0.00011145266,0.0000416107,0.0023870328],"genre_scores_gemma":[0.99317646,0.0035104323,0.00054541207,0.0009870323,0.00095647335,1.8620298e-8,0.0000070950487,0.000040703788,0.00077638886],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99765354,0.00032633884,0.0008106618,0.00022989008,0.0004201478,0.0005594026],"domain_scores_gemma":[0.9976289,0.00054840744,0.0008452109,0.0003374234,0.00035772898,0.0002822898],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009484407,0.0003602436,0.0005593308,0.00017589428,0.0004068092,0.000065511354,0.0008766844,0.00029273602,0.0016379398],"category_scores_gemma":[0.00012306836,0.00024645147,0.0002649022,0.0004233174,0.00050849584,0.00026216343,0.00016174253,0.0012705598,0.00019149798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013654702,0.004040786,0.09529604,0.00010746096,0.002412036,0.00060298806,0.0026165182,0.00061099126,0.8542558,0.00064687233,0.027876373,0.0101686595],"study_design_scores_gemma":[0.0077618742,0.0015300151,0.07943433,0.00033674017,0.001871233,0.0011830667,0.0015191977,0.009310636,0.84036356,0.00032381993,0.055384535,0.0009810125],"about_ca_topic_score_codex":0.00003916393,"about_ca_topic_score_gemma":0.000009996677,"teacher_disagreement_score":0.027508164,"about_ca_system_score_codex":0.00007377301,"about_ca_system_score_gemma":0.000048967995,"threshold_uncertainty_score":0.99999875},"labels":[],"label_agreement":null},{"id":"W2201671543","doi":"10.6000/1927-7229.2015.04.04.2","title":"Standardized Extract of the Persian Gulf Sponge, Axinella Sinoxea Selectively Induces Apoptosis through Mitochondria in Human Chronic Lymphocytic Leukemia Cells","year":2015,"lang":"en","type":"article","venue":"Journal of Analytical Oncology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Mitochondrion; Chronic lymphocytic leukemia; Leukemia; Biology; Apoptosis; Cytochrome c; Reactive oxygen species; Biochemistry; Immunology","score_opus":0.1529341826526883,"score_gpt":0.44773091317054275,"score_spread":0.2947967305178545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2201671543","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9849938,0.0005618983,0.0001896594,0.0008777451,0.0015557621,0.0002440817,0.000022132639,0.00000884586,0.011546051],"genre_scores_gemma":[0.99782383,0.00020253428,0.0003558388,0.00048769338,0.0005505979,0.0000031701004,0.0000016196728,0.00002217643,0.0005525433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99639654,0.0011786285,0.0011024742,0.00027664736,0.00044569527,0.00060000137],"domain_scores_gemma":[0.99742573,0.000556018,0.0009303707,0.00019594937,0.0005384739,0.00035343866],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016584423,0.0002864806,0.0009886147,0.00023729136,0.00015142809,0.000022758366,0.0006684386,0.0005331731,0.00046352574],"category_scores_gemma":[0.0002910662,0.00020183349,0.0004322588,0.00062672433,0.00072757265,0.00021938345,0.00014179636,0.0014311881,0.000012528836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":true,"about_ca_system_consensus":true,"study_design_scores_codex":[0.008306833,0.0025707055,0.022124128,0.00019243063,0.0027207523,0.0007926961,0.0048737684,0.011736134,0.88588494,0.0035284671,0.051350694,0.005918429],"study_design_scores_gemma":[0.039572097,0.010012041,0.020985777,0.00035429464,0.002656356,0.0009746621,0.0035070048,0.009845345,0.61907816,0.005890739,0.28595394,0.0011696056],"about_ca_topic_score_codex":0.000095305724,"about_ca_topic_score_gemma":0.00008494401,"teacher_disagreement_score":0.2668068,"about_ca_system_score_codex":0.00792143,"about_ca_system_score_gemma":0.0056595714,"threshold_uncertainty_score":0.9999774},"labels":[],"label_agreement":null},{"id":"W2212511730","doi":"10.1007/0-387-23188-9_2","title":"Topology and Transmembrane Organization of Ryanodine Receptors","year":2006,"lang":"en","type":"book-chapter","venue":"Kluwer Academic Publishers eBooks","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Ryanodine receptor; Topology (electrical circuits); Transmembrane domain; Transmembrane protein; Receptor; Neuroscience; Computer science; Biology; Mathematics; Genetics; Combinatorics","score_opus":0.06981009031614559,"score_gpt":0.35003076665538935,"score_spread":0.28022067633924375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2212511730","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011897828,0.0012722157,0.0001016625,0.0012788505,0.0027252852,0.00059775927,0.00017114566,0.00015540839,0.98179984],"genre_scores_gemma":[0.20956239,0.0004141915,0.000081909726,0.0014985439,0.00089897506,0.0000115999155,0.00040931025,0.00015927468,0.7869638],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99785024,0.00011712942,0.0007499432,0.0005993078,0.0002476111,0.0004357422],"domain_scores_gemma":[0.99859834,0.00017175198,0.0005084901,0.00022379118,0.000268301,0.00022931631],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0004501475,0.00051035103,0.000718448,0.00035210812,0.00016999009,0.000041695483,0.00046553614,0.0024420808,0.0030581143],"category_scores_gemma":[0.00003968295,0.00051066664,0.00013442653,0.00006147175,0.0009508544,0.00023549423,0.0001475213,0.0023545795,0.000026334728],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028785682,0.000108494336,0.0061816694,0.0005852144,0.0010958832,0.00006092181,0.00090422237,0.000014416908,0.025027035,0.06299757,0.86063117,0.042105556],"study_design_scores_gemma":[0.0012800975,0.00008626838,0.00023079885,0.000075078286,0.00039548427,0.00005274842,0.000026769787,0.000020112842,0.006972386,0.0040102876,0.98632616,0.00052382296],"about_ca_topic_score_codex":0.000025231444,"about_ca_topic_score_gemma":0.000004909951,"teacher_disagreement_score":0.19766456,"about_ca_system_score_codex":0.000093395676,"about_ca_system_score_gemma":0.00015163189,"threshold_uncertainty_score":0.999947},"labels":[],"label_agreement":null},{"id":"W2257382202","doi":"10.1155/2016/8253726","title":"Evaluating the Effects of Tetrachloro-1,4-benzoquinone, an Active Metabolite of Pentachlorophenol, on the Growth of Human Breast Cancer Cells","year":2016,"lang":"en","type":"article","venue":"Journal of Toxicology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"College of Pharmacy and Nutrition, University of Saskatchewan; University of Saskatchewan","keywords":"Cytotoxicity; Apoptosis; Pentachlorophenol; Oxidative stress; Intracellular; Metabolite; Chemistry; Reactive oxygen species; Cancer cell; DNA damage; Cancer research; Biochemistry; Pharmacology; Biology; Cancer; In vitro; DNA; Environmental chemistry; Genetics","score_opus":0.1352291607677549,"score_gpt":0.46663018879719415,"score_spread":0.33140102802943927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2257382202","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955401,0.0005294496,0.00001889796,0.0015156878,0.0015815465,0.00036131605,0.00014471018,0.0000043741425,0.00030396093],"genre_scores_gemma":[0.998445,0.00042936296,0.000046016452,0.0006103813,0.00033674575,0.00001376119,7.3111335e-7,0.000020810572,0.000097233686],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99664193,0.0016400269,0.0008286843,0.00019322852,0.00036452964,0.00033159406],"domain_scores_gemma":[0.9947004,0.0024429034,0.0018563861,0.0002466484,0.000632311,0.00012139471],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015494415,0.00022978328,0.0006676207,0.00016795911,0.00019715494,0.0000061438004,0.000742947,0.00021479926,0.0008700229],"category_scores_gemma":[0.00021829893,0.00010885411,0.00028879027,0.00019753884,0.0008267703,0.00017450427,0.00011175754,0.0006420597,0.0000029335756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015647397,0.0011539804,0.0076199947,0.00010253654,0.0007743407,0.000015199876,0.0006904404,0.000022655606,0.9755839,0.0020766645,0.00039725352,0.009998312],"study_design_scores_gemma":[0.002220844,0.003319584,0.09024925,0.00011381303,0.00055492576,0.00005246997,0.00021181078,0.000033747463,0.90217364,0.00082930864,0.00012678807,0.000113824186],"about_ca_topic_score_codex":0.00003123486,"about_ca_topic_score_gemma":0.000014700801,"teacher_disagreement_score":0.08262925,"about_ca_system_score_codex":0.00008334259,"about_ca_system_score_gemma":0.00016895887,"threshold_uncertainty_score":0.95261407},"labels":[],"label_agreement":null},{"id":"W2300347061","doi":"10.1139/cjpp-2015-0465","title":"Antinociceptive properties of shikonin: in vitro and in vivo studies","year":2016,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Pharmacology; Nociception; Analgesic; In vivo; Hyperalgesia; Chemistry; IC50; Sodium channel; Sodium channel blocker; Morphine; In vitro; Medicine; Sodium; Receptor; Biochemistry; Biology","score_opus":0.12630724654629905,"score_gpt":0.3908942870543978,"score_spread":0.2645870405080988,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2300347061","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894874,0.007791524,0.0000010440287,0.0015510704,0.0008691699,0.00013094085,0.000035582067,0.000002102878,0.00013117438],"genre_scores_gemma":[0.99622476,0.002728345,0.000024944307,0.0007969806,0.00013538479,0.0000063895063,3.1102263e-7,0.000008329494,0.000074551244],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99841005,0.00054719346,0.00044031805,0.00018527928,0.000038182414,0.00037900358],"domain_scores_gemma":[0.999036,0.00029940243,0.00024358922,0.000044619053,0.00013828979,0.00023806446],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000527261,0.00016249799,0.00052768993,0.00039625,0.00008195326,0.0000026514308,0.00014652747,0.00019581427,0.00045012528],"category_scores_gemma":[0.00006199166,0.00011150245,0.000047364178,0.00013690985,0.001327415,0.00013993988,0.000040468003,0.00040374094,0.0000016507933],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00097364734,0.000061039435,0.0338474,0.00009912685,0.0001860949,0.00013373954,0.0012968166,0.0000059996414,0.961183,0.000093208655,0.0005895,0.0015304035],"study_design_scores_gemma":[0.0030794411,0.00023753497,0.031406157,0.000091524555,0.0000670486,0.000099095545,0.00052241393,0.00002225554,0.9598723,0.0008145032,0.003635569,0.00015212438],"about_ca_topic_score_codex":0.00017554565,"about_ca_topic_score_gemma":0.0010812889,"teacher_disagreement_score":0.0067373724,"about_ca_system_score_codex":0.00007092842,"about_ca_system_score_gemma":0.0002816054,"threshold_uncertainty_score":0.4928556},"labels":[],"label_agreement":null},{"id":"W2322439409","doi":"10.1021/tx200365r","title":"Hydroxyl Radical-Induced Oxidation of a Phenolic C-Linked 2′-Deoxyguanosine Adduct Yields a Reactive Catechol","year":2011,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Chemistry; Adduct; Deoxyguanosine; Catechol; Hydroxyl radical; Hydroxylation; Moiety; Reactivity (psychology); Medicinal chemistry; Horseradish peroxidase; Stereochemistry; DNA oxidation; Radical; DNA; DNA damage; Organic chemistry; Biochemistry; Enzyme","score_opus":0.5500672748851677,"score_gpt":0.52679628029913,"score_spread":0.023270994586037763,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2322439409","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98241657,0.00017794549,0.000022660603,0.0012023676,0.00036750504,0.0007003359,0.000019888996,0.000051089737,0.015041654],"genre_scores_gemma":[0.9985096,0.0001588697,0.0003190833,0.00040694914,0.00019654728,0.00019515163,0.000029670953,0.000033252458,0.00015087433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9961943,0.0010857888,0.00063679373,0.0006524736,0.00038685836,0.0010437819],"domain_scores_gemma":[0.99769574,0.001041281,0.00018200002,0.00039123424,0.00030621543,0.0003835295],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0020049731,0.00026327028,0.00054342765,0.00053743983,0.0001319109,0.000010155152,0.00073620887,0.0013387689,0.0018501105],"category_scores_gemma":[0.0010475005,0.0002533334,0.00012451241,0.0010071815,0.0012804448,0.00015071698,0.00036918733,0.003284526,0.00012630704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013146013,0.0019982108,0.0029362014,0.000065333756,0.00010638864,0.00012542376,0.0009918974,5.434007e-7,0.9826997,0.0023770828,0.0012498718,0.0061347443],"study_design_scores_gemma":[0.002117247,0.000534628,0.0042198943,0.000043512522,0.000028243625,0.00003136331,0.00017416499,0.00021890033,0.9826498,0.0045889965,0.005160086,0.00023317694],"about_ca_topic_score_codex":0.00016959225,"about_ca_topic_score_gemma":0.000026023316,"teacher_disagreement_score":0.016093047,"about_ca_system_score_codex":0.00032446094,"about_ca_system_score_gemma":0.00028149836,"threshold_uncertainty_score":0.9999919},"labels":[],"label_agreement":null},{"id":"W2336701277","doi":"10.1016/j.tetlet.2015.07.046","title":"Synthesis of novel 2-(fluoroanilino)-3-(2,4-dinitroanilino) derivatives of 1,4-naphthoquinone","year":2015,"lang":"en","type":"article","venue":"Tetrahedron Letters","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Consejo Nacional de Ciencia y Tecnología","keywords":"Chemistry; 1,4-Naphthoquinone; Aniline; Naphthoquinone; Nucleophile; Substituent; Polar effect; Lewis acids and bases; Chlorine atom; Medicinal chemistry; Combinatorial chemistry; Organic chemistry; Catalysis","score_opus":0.21727030732445327,"score_gpt":0.41808415234169766,"score_spread":0.2008138450172444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2336701277","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919986,0.00031524705,0.0012082462,0.0009845573,0.00071178714,0.00024175788,0.0001255988,0.00005690339,0.0043572993],"genre_scores_gemma":[0.99563533,0.000041328127,0.0030595588,0.00097443996,0.00013773912,0.000018656267,0.000010758601,0.000031030115,0.00009117942],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99812984,0.00024066397,0.00058708887,0.00033158384,0.00031151072,0.0003993342],"domain_scores_gemma":[0.9984168,0.0005180854,0.00036695538,0.0002824829,0.00018329684,0.00023239345],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00067352975,0.00027055937,0.00053520116,0.00020460863,0.00006883426,0.000007852187,0.0004241734,0.0001958489,0.0003893083],"category_scores_gemma":[0.00026561835,0.00025475764,0.00018396815,0.000328176,0.00066513405,0.00015689147,0.000105617895,0.00037048035,0.000022927732],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043919493,0.0010203862,0.0424816,0.00011002345,0.00031034285,0.000020228212,0.00066300126,0.00024111426,0.94468814,0.0006382931,0.005453839,0.0039338535],"study_design_scores_gemma":[0.0025886477,0.00025512563,0.022141159,0.000065242624,0.00019759411,0.000029230729,0.00071965036,0.0008804193,0.96524286,0.000068407506,0.0074256496,0.0003860241],"about_ca_topic_score_codex":0.000051042553,"about_ca_topic_score_gemma":0.0000037996522,"teacher_disagreement_score":0.02055473,"about_ca_system_score_codex":0.00007478091,"about_ca_system_score_gemma":0.00008817331,"threshold_uncertainty_score":0.99999046},"labels":[],"label_agreement":null},{"id":"W2341723586","doi":"10.1021/acs.biochem.5b00884","title":"Binding of DNA-Intercalating Agents to Oxidized and Reduced Quinone Reductase 2","year":2015,"lang":"en","type":"article","venue":"Biochemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Ethidium bromide; Chemistry; Acridine orange; Intercalation (chemistry); DNA; Stereochemistry; Quinone; Biochemistry; Apoptosis; Organic chemistry","score_opus":0.20229488950730232,"score_gpt":0.4467908554356698,"score_spread":0.2444959659283675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2341723586","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957596,0.00019150662,0.000009640727,0.00038860875,0.00044534137,0.00013019046,0.000065292974,0.000032811746,0.0029770136],"genre_scores_gemma":[0.99784976,0.000017769918,0.00064568454,0.00023759172,0.0001633724,0.000009439802,0.000027406986,0.000014229777,0.0010347501],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902374,0.00007131633,0.00025396064,0.00028388205,0.000118682205,0.0002484388],"domain_scores_gemma":[0.9992162,0.00004712154,0.00011725659,0.00015088289,0.00009021374,0.00037830928],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033815476,0.00015306265,0.00021254357,0.000048993283,0.00007607007,0.000014206953,0.0001571934,0.00016479797,0.00014824343],"category_scores_gemma":[0.00019297597,0.00015274044,0.000048442223,0.00014367358,0.00012753147,0.0000404257,0.00015901423,0.00020199684,0.000023792478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021648011,0.00012727948,0.0028255198,0.00005771948,0.00006222508,0.000018059043,0.0003679953,0.0000014551671,0.98245215,0.000012276689,0.012881968,0.0009768454],"study_design_scores_gemma":[0.0011342998,0.00006301033,0.0004179151,0.000046965557,0.00004339204,0.000025113122,0.00050747866,0.000088943474,0.993374,0.000029124276,0.0041033193,0.00016645805],"about_ca_topic_score_codex":0.000010672892,"about_ca_topic_score_gemma":5.923933e-7,"teacher_disagreement_score":0.010921804,"about_ca_system_score_codex":0.00005626079,"about_ca_system_score_gemma":0.00006482476,"threshold_uncertainty_score":0.62285745},"labels":[],"label_agreement":null},{"id":"W2377781261","doi":"","title":"Tissue Distribution and Excretion of Radioactivity in Mice After Intragastric Administration of ~3H-β,β-dimethylacrylshikonin","year":2008,"lang":"en","type":"article","venue":"","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CAE (Canada)","funders":"","keywords":"Urine; Excretion; Feces; Chemistry; Kidney; Distribution (mathematics); Internal medicine; Endocrinology; Biology; Medicine; Biochemistry","score_opus":0.07154764715155887,"score_gpt":0.3904746898034398,"score_spread":0.31892704265188093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2377781261","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965464,0.0002982976,0.0020231698,0.00013992841,0.00014038618,0.0001985853,0.000090708294,0.000011680691,0.00055083423],"genre_scores_gemma":[0.9992001,0.00031038586,0.00025100465,0.000038367638,0.000032857373,0.00001209321,0.0000468005,0.0000054758452,0.000102922124],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901676,0.00024378377,0.00030493873,0.00018041796,0.00009573116,0.00015837986],"domain_scores_gemma":[0.9995262,0.00013042576,0.00014419219,0.00006940223,0.00006329665,0.00006650609],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003151145,0.0001148476,0.00022160815,0.00008322291,0.00004638647,0.0000028466523,0.000059767524,0.00016741361,0.0002636044],"category_scores_gemma":[0.00003799607,0.00011106741,0.000034014425,0.00023203189,0.00027932192,0.00014070299,0.000029140041,0.00022664829,0.0000030347253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025514867,0.0013222258,0.35956216,0.00017345698,0.000078347366,0.00010032631,0.0005426501,0.000025940046,0.6140839,0.0008912035,0.00044975698,0.020218568],"study_design_scores_gemma":[0.00078796776,0.00023629231,0.48681465,0.000011177098,0.000027007598,0.000054347765,0.000041793875,0.00039487396,0.51064414,0.00006388358,0.0008316919,0.00009216651],"about_ca_topic_score_codex":0.000062405765,"about_ca_topic_score_gemma":0.00003254707,"teacher_disagreement_score":0.12725247,"about_ca_system_score_codex":0.000039384344,"about_ca_system_score_gemma":0.000050783245,"threshold_uncertainty_score":0.45291975},"labels":[],"label_agreement":null},{"id":"W2392724482","doi":"","title":"Anti-tumor effect of 2-acetyl-furonaphthoquinone and its derivatives","year":2014,"lang":"en","type":"article","venue":"Central South Pharmacy","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Furan; Traditional medicine; Broad spectrum; Stereochemistry; Chemistry; Cancer research; Medicine; Combinatorial chemistry; Organic chemistry","score_opus":0.07704147419494918,"score_gpt":0.4030437964838809,"score_spread":0.3260023222889317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2392724482","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953198,0.0012096117,0.00024717307,0.00020611197,0.0009476656,0.00044094885,0.000088077795,0.0000754722,0.0014651503],"genre_scores_gemma":[0.9986115,0.0002017963,0.00006295341,0.00060986774,0.00029276818,0.000017321106,0.000015850903,0.000031143823,0.00015679564],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99773055,0.000725908,0.00034210665,0.0003952343,0.00016327067,0.00064295006],"domain_scores_gemma":[0.9989004,0.00031156396,0.00021879742,0.00013273288,0.00006593015,0.00037057203],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00053845084,0.0003241394,0.0005051847,0.00008418451,0.00022328767,0.000020827012,0.00025074385,0.00008514015,0.0008456103],"category_scores_gemma":[0.000117622505,0.00027463623,0.00013137185,0.0001843245,0.00028832923,0.00015825579,0.00014349024,0.0004476597,0.000057012676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008106941,0.00027068544,0.4117871,0.0004510534,0.00032186386,0.000034123186,0.0011521974,0.000051296447,0.5711797,0.0008909768,0.0007956303,0.0122546675],"study_design_scores_gemma":[0.006568589,0.00042371187,0.06971597,0.00004653706,0.00027043215,0.00003426222,0.000057620036,0.0045796377,0.8428952,0.000035881687,0.07492875,0.00044338498],"about_ca_topic_score_codex":0.000005375926,"about_ca_topic_score_gemma":3.4967914e-7,"teacher_disagreement_score":0.34207112,"about_ca_system_score_codex":0.000022940148,"about_ca_system_score_gemma":0.000029195475,"threshold_uncertainty_score":0.99997056},"labels":[],"label_agreement":null},{"id":"W2413639144","doi":"10.4238/2015.december.21.18","title":"O-naphthoquinone isolated from Capraria biflora L. induces selective cytotoxicity in tumor cell lines","year":2015,"lang":"en","type":"article","venue":"Genetics and Molecular Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Cytotoxicity; HeLa; Apoptosis; Cell culture; Cytotoxic T cell; Molecular biology; Chemistry; Biology; Biochemistry; In vitro; Genetics","score_opus":0.2512293310422111,"score_gpt":0.4745100904099936,"score_spread":0.22328075936778247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2413639144","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911519,0.005240436,0.00013247153,0.0004944968,0.0002259131,0.00042426217,0.000106267405,0.000017714334,0.0022065074],"genre_scores_gemma":[0.99823534,0.0006865929,0.00031291906,0.00040376597,0.00010005544,0.00003741496,0.000035830282,0.000028833147,0.00015924833],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974748,0.0008349929,0.00025386745,0.0005012487,0.00033925253,0.0005958533],"domain_scores_gemma":[0.99881464,0.00013053254,0.00007467352,0.00023937355,0.00033179135,0.00040895963],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001025729,0.00020214313,0.00024902407,0.00018433819,0.00026861712,0.00011965624,0.00036703527,0.00026043184,0.00006367381],"category_scores_gemma":[0.00011265715,0.00019718538,0.00003999498,0.00036514812,0.00037237114,0.00006287861,0.00041868244,0.0010465303,0.000033145505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003292073,0.00045857963,0.02134995,0.000015784888,0.00006462374,0.00028220288,0.00047431217,0.000035506408,0.9714448,0.000054071395,0.0044154446,0.0010755406],"study_design_scores_gemma":[0.0024990486,0.0004943439,0.009114419,0.000018413635,0.000026907841,0.000007655512,0.00036332064,0.0036665632,0.97134167,0.0016511587,0.010504791,0.00031173122],"about_ca_topic_score_codex":0.00068060507,"about_ca_topic_score_gemma":0.00008875819,"teacher_disagreement_score":0.012235531,"about_ca_system_score_codex":0.00006940779,"about_ca_system_score_gemma":0.00017785458,"threshold_uncertainty_score":0.8040986},"labels":[],"label_agreement":null},{"id":"W2540213618","doi":"10.1158/1557-3265.hemmal14-a19","title":"Abstract A19: MALT1 inhibition as an anchor for combinatorial therapy of ABC-DLBCL.","year":2015,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency; Université de Montréal","funders":"","keywords":"Cancer research; breakpoint cluster region; Diffuse large B-cell lymphoma; Chemistry; Cell growth; Biology; Lymphoma; Molecular biology; Cell biology; Receptor; Biochemistry; Immunology","score_opus":0.7850792158000355,"score_gpt":0.6958353942198646,"score_spread":0.08924382158017086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2540213618","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98987335,0.0011464597,0.0000116462215,0.001395038,0.0035618974,0.0008467446,0.00015161558,0.000030363522,0.0029828714],"genre_scores_gemma":[0.9943081,0.002281427,0.000059045444,0.0006482708,0.0021444713,0.0001936441,0.00004461906,0.000027461929,0.000292976],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971451,0.000878916,0.0005778075,0.00043147037,0.00044469011,0.0005219917],"domain_scores_gemma":[0.99681216,0.0011664465,0.00015982785,0.00024749446,0.0010459636,0.00056809676],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0063257325,0.00014585031,0.00035657253,0.00008399364,0.00022355819,0.0000316615,0.0003345246,0.00042366397,0.0009536217],"category_scores_gemma":[0.0006012387,0.0001269754,0.00016328889,0.00023989262,0.0008006728,0.00016765553,0.00009137276,0.001152775,0.00007070229],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.060004517,0.021490674,0.1774952,0.00036448648,0.0009022372,0.00012663467,0.0012231716,0.00004548359,0.06387815,0.02561027,0.3270511,0.3218081],"study_design_scores_gemma":[0.028594617,0.006725105,0.04530979,0.000086733606,0.000039885825,0.0000039958436,0.0004070419,0.0004301516,0.083960846,0.04139673,0.7926006,0.00044456238],"about_ca_topic_score_codex":0.0001918901,"about_ca_topic_score_gemma":0.000037463473,"teacher_disagreement_score":0.46554947,"about_ca_system_score_codex":0.00010315171,"about_ca_system_score_gemma":0.00069567695,"threshold_uncertainty_score":0.99995965},"labels":[],"label_agreement":null},{"id":"W2546616443","doi":"10.1016/j.ceca.2016.10.004","title":"Ligand binding to Ryanodine Receptors revealed through cryo-electron microscopy","year":2016,"lang":"en","type":"article","venue":"Cell Calcium","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Ryanodine receptor; Cryo-electron microscopy; Biophysics; Electron microscope; Receptor; Ligand (biochemistry); Chemistry; Crystallography; Cell biology; Biology; Biochemistry; Physics; Optics","score_opus":0.11801871599099709,"score_gpt":0.4409372870713758,"score_spread":0.3229185710803787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2546616443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97925127,0.00041768065,0.0010927696,0.0027415145,0.0031290376,0.0003941698,0.000065186265,0.00011758871,0.012790815],"genre_scores_gemma":[0.9645976,0.00030760845,0.0005209142,0.0025507885,0.00053296634,0.00003269135,0.000014869984,0.000045384648,0.031397197],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99811596,0.00019184232,0.00030974878,0.0004983642,0.00014109327,0.0007429789],"domain_scores_gemma":[0.99908155,0.00018037071,0.00011642231,0.0002405861,0.000088837594,0.0002922149],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00032653988,0.00028955392,0.0003064984,0.00009889166,0.0003183976,0.000031304968,0.00033535165,0.00027641936,0.001644293],"category_scores_gemma":[0.00004410049,0.0002137328,0.00012582375,0.00029068903,0.00014973004,0.00014482233,0.00013411109,0.0003500728,0.0018753549],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025880247,0.00017462578,0.008500959,0.000027102908,0.000042319905,0.000018894978,0.00021748253,0.0000011088742,0.8772661,0.00011213054,0.11217896,0.0012015083],"study_design_scores_gemma":[0.0008969048,0.00014948066,0.0004008435,0.000024555966,0.000035573197,0.0000050564117,0.00002131851,0.0000023805942,0.5835885,0.00006465489,0.41460508,0.00020566603],"about_ca_topic_score_codex":0.000012096055,"about_ca_topic_score_gemma":0.000004820306,"teacher_disagreement_score":0.30242613,"about_ca_system_score_codex":0.00017441332,"about_ca_system_score_gemma":0.00006652058,"threshold_uncertainty_score":0.99926835},"labels":[],"label_agreement":null},{"id":"W2549813000","doi":"10.1182/blood.v108.11.3421.3421","title":"Chemical Library Screening Identifies Novel Inhibitors of Cyclin D2 (CCND2) Transactivation That Selectively Induce Apoptosis in Multiple Myeloma Cells.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Cyclin D2; Cancer research; Cell cycle; Biology; Chemistry; Cyclin; Molecular biology; Apoptosis; Biochemistry","score_opus":0.07967812500013023,"score_gpt":0.3235447068192255,"score_spread":0.24386658181909526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2549813000","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974776,0.00018451326,0.00051573256,0.00014824138,0.00030625745,0.00028871335,0.00009212344,0.000071016504,0.0009158273],"genre_scores_gemma":[0.99826324,0.00003597538,0.0011238687,0.00011901265,0.00019243304,0.000027214586,0.000058067206,0.000032875498,0.00014730298],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99857396,0.00013835836,0.00040974352,0.0003570348,0.00017604463,0.00034486523],"domain_scores_gemma":[0.9993025,0.00026950226,0.0002024993,0.00010883758,0.000042244144,0.000074422685],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019660544,0.00022729051,0.00030060633,0.00020207472,0.000113724964,0.000027756298,0.00021153584,0.00033468063,0.000120081386],"category_scores_gemma":[0.000018591425,0.00023706428,0.00012634236,0.00042253506,0.00016743831,0.00039660654,0.000056080742,0.00055607496,0.000006068671],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018300458,0.0017475527,0.17702481,0.000047912807,0.00008685821,0.0000049818927,0.00020799457,0.00006469624,0.8190997,0.00003110445,0.00028560794,0.0012157204],"study_design_scores_gemma":[0.003474555,0.000033427128,0.08843738,0.000048706945,0.000084437204,0.0000042161137,0.000117673655,0.0003938702,0.90650547,0.00006220866,0.0006152542,0.00022283017],"about_ca_topic_score_codex":0.0001227873,"about_ca_topic_score_gemma":0.000020032034,"teacher_disagreement_score":0.08858744,"about_ca_system_score_codex":0.00001983878,"about_ca_system_score_gemma":0.000044071137,"threshold_uncertainty_score":0.9667201},"labels":[],"label_agreement":null},{"id":"W2586187189","doi":"10.1093/annonc/mdw370.03","title":"A randomized phase III study of napabucasin [BBI608] (NAPA) vs placebo (PBO) in patients (pts) with pretreated advanced colorectal cancer (ACRC): the CCTG/AGITG CO.23 trial","year":2016,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; University of Alberta; University of Toronto; Vancouver General Hospital; Ottawa Hospital; Princess Margaret Cancer Centre; University of Ottawa","funders":"","keywords":"NAPA; Medicine; Internal medicine; Gastroenterology; Placebo; Nausea; Clinical endpoint; Phases of clinical research; Cancer; Progression-free survival; Randomized controlled trial; Clinical trial; Overall survival; Pathology","score_opus":0.1505263278603289,"score_gpt":0.49311956011415614,"score_spread":0.3425932322538272,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2586187189","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907485,0.00017818593,0.000010464352,0.0011960155,0.00084867317,0.004841681,0.00020806014,0.000028623252,0.0019397765],"genre_scores_gemma":[0.99781835,0.00047222103,0.000015361324,0.00049756636,0.000101268255,0.0007278434,0.000022701523,0.0000308613,0.00031380903],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9948409,0.0027313435,0.0010529716,0.0004879353,0.00030503655,0.00058179686],"domain_scores_gemma":[0.9958615,0.0022193,0.0010098577,0.00025894324,0.00049624895,0.00015416666],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017565516,0.00037143912,0.0015401995,0.00022394642,0.00015980385,0.000007858357,0.00046025944,0.00032524072,0.00069837214],"category_scores_gemma":[0.00029524157,0.00020610944,0.0001995164,0.00040004513,0.0010723494,0.00016077183,0.00010733333,0.00046208047,0.000011247169],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.92557895,0.014502372,0.023074972,0.000024775876,0.0012010381,0.000039986146,0.0021954074,0.000031845913,0.0037080827,0.000056106925,0.0019434959,0.027642937],"study_design_scores_gemma":[0.93987,0.021756418,0.005577152,0.00007152375,0.0003344177,0.0000039948186,0.00052454916,0.00008757102,0.02397621,0.000050214934,0.0074696066,0.0002783384],"about_ca_topic_score_codex":0.00020557735,"about_ca_topic_score_gemma":0.00069225125,"teacher_disagreement_score":0.0273646,"about_ca_system_score_codex":0.00010879479,"about_ca_system_score_gemma":0.0003295023,"threshold_uncertainty_score":0.84048986},"labels":[],"label_agreement":null},{"id":"W2594470329","doi":"10.1111/jphp.12712","title":"Characterization of anti-inflammatory effect and possible mechanism of action of <i>Tibouchina granulosa</i>","year":2017,"lang":"en","type":"article","venue":"Journal of Pharmacy and Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Carrageenan; Inflammation; Anti-inflammatory; Mechanism of action; Pharmacology; Cytokine; Antioxidant; Chemistry; Biology; Immunology; Biochemistry; In vitro","score_opus":0.06871365069374713,"score_gpt":0.42075017594187736,"score_spread":0.3520365252481302,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2594470329","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958461,0.0006419924,0.00015384932,0.00032289655,0.0024050383,0.00029644585,0.00008828494,0.000006876251,0.00023852213],"genre_scores_gemma":[0.993574,0.0058196993,0.000059577866,0.00016352354,0.00031456357,0.0000039262236,0.000005677456,0.000017945384,0.00004103489],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997978,0.000550987,0.000845608,0.00018898227,0.00019052986,0.00024593217],"domain_scores_gemma":[0.9966966,0.00024984012,0.002426896,0.00012828696,0.00030791175,0.00019047578],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012932897,0.00023768905,0.00075189845,0.00025389294,0.0002766225,0.000015913987,0.0003376886,0.00016781324,0.00032696346],"category_scores_gemma":[0.000045297922,0.00020628635,0.00016687223,0.000077836325,0.0006149014,0.0004973349,0.00013907907,0.000564837,9.2706205e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020870832,0.0003316306,0.08465184,0.00070593273,0.0005080764,0.000040431452,0.00031782707,0.0000049512723,0.9017877,0.00033149836,0.00013773072,0.009095304],"study_design_scores_gemma":[0.0067163403,0.0006202994,0.037860252,0.000059649352,0.0008041915,0.00016369624,0.000025544665,0.00079703314,0.9496585,0.00023242195,0.0029108196,0.00015121394],"about_ca_topic_score_codex":0.000020531816,"about_ca_topic_score_gemma":0.0000020084365,"teacher_disagreement_score":0.04787084,"about_ca_system_score_codex":0.000018265346,"about_ca_system_score_gemma":0.00010026191,"threshold_uncertainty_score":0.8412113},"labels":[],"label_agreement":null},{"id":"W2603977557","doi":"10.1200/jco.2017.35.4_suppl.593","title":"Cancer stemness inhibition and chemosensitization: Phase 1b/II study of cancer stemness inhibitor napabucasin (BBI-608) with FOLFIRI +/- bevacizumab (Bev) administered to colorectal cancer (CRC) patients (pts).","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Medicine; Irinotecan; Colorectal cancer; Bevacizumab; Internal medicine; Cancer; FOLFIRI; Tolerability; Oncology; Phases of clinical research; Combination therapy; Pharmacology; Gastroenterology; Adverse effect; Chemotherapy","score_opus":0.28323780627631084,"score_gpt":0.5737039434525277,"score_spread":0.2904661371762169,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2603977557","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98949516,0.0003739648,0.000017438659,0.0032996822,0.0052936054,0.0010410371,0.00021527255,0.0000131002525,0.00025072164],"genre_scores_gemma":[0.99597234,0.0005902058,0.00007821853,0.0014866064,0.0015483467,0.000095880925,0.0000079301035,0.000040895833,0.0001795559],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9954709,0.000937899,0.00214366,0.0005090934,0.00049956253,0.0004388984],"domain_scores_gemma":[0.9927837,0.0006962186,0.0039933496,0.00026061857,0.0017083824,0.0005577276],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0016698425,0.00037690465,0.0017281236,0.00017609111,0.00078830094,0.00005970369,0.00040340557,0.0005807364,0.0003465163],"category_scores_gemma":[0.0005251337,0.0002919934,0.00020327278,0.00019005836,0.0006352836,0.0004365528,0.00032271934,0.0012743531,0.0000030965102],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.037695114,0.026211645,0.75064313,0.00017374511,0.001799253,0.00046668146,0.0023405137,0.00010758369,0.004837951,0.000021941323,0.0042057484,0.17149669],"study_design_scores_gemma":[0.1177379,0.050770495,0.7634136,0.0006769111,0.0023640606,0.000092999835,0.0017607382,0.0003318222,0.02056927,0.000041552285,0.04139785,0.0008428144],"about_ca_topic_score_codex":0.00035445133,"about_ca_topic_score_gemma":0.00480737,"teacher_disagreement_score":0.17065388,"about_ca_system_score_codex":0.00031056404,"about_ca_system_score_gemma":0.0012236205,"threshold_uncertainty_score":0.9999532},"labels":[],"label_agreement":null},{"id":"W2622706150","doi":"10.1200/jco.2017.35.15_suppl.1084","title":"A phase 2 study of napabucasin with weekly paclitaxel in previously treated metastatic breast cancer.","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St Mary's Hospital Centre","funders":"","keywords":"Medicine; Metastatic breast cancer; Breast cancer; Paclitaxel; Internal medicine; Taxane; Cancer; Oncology; Adverse effect; Pharmacology","score_opus":0.438716383470474,"score_gpt":0.6221150318501938,"score_spread":0.1833986483797198,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2622706150","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940593,0.00030439923,0.000011306797,0.0029639911,0.0010736763,0.00047465603,0.00004806815,0.0000055866603,0.0010590025],"genre_scores_gemma":[0.9981146,0.0006585956,0.0001974991,0.00045349938,0.00033821698,0.000015451806,0.0000010678267,0.000017784458,0.00020329283],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99509746,0.0018426041,0.002199017,0.00025572078,0.00025453608,0.0003506847],"domain_scores_gemma":[0.99350524,0.0013529515,0.0040253913,0.00028810583,0.00047086895,0.00035744318],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0040950566,0.00021790335,0.0017510743,0.00015777834,0.00017021305,0.000021071017,0.000629122,0.00026494585,0.00041646496],"category_scores_gemma":[0.0006579674,0.00014582241,0.00025350324,0.00012680756,0.00061581907,0.00025347783,0.00009581191,0.001487455,0.0000053898866],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.020002818,0.045623682,0.782047,0.000044238448,0.0016219259,0.0024735094,0.0006264312,0.000043926768,0.00059451465,0.000035128687,0.0012575787,0.14562926],"study_design_scores_gemma":[0.07847775,0.047599908,0.8590037,0.00015437164,0.0015032479,0.0004780463,0.0012906382,0.00033066957,0.00025571822,0.00011706066,0.010544313,0.00024453874],"about_ca_topic_score_codex":0.00034884308,"about_ca_topic_score_gemma":0.0012215886,"teacher_disagreement_score":0.14538471,"about_ca_system_score_codex":0.00011646403,"about_ca_system_score_gemma":0.0008677982,"threshold_uncertainty_score":0.64623344},"labels":[],"label_agreement":null},{"id":"W2722759707","doi":"10.1200/jco.2017.35.15_suppl.e13525","title":"BBI608-201GBM: A phase Ib/II clinical study of napabucasin (BBI608) in combination with temozolomide (TMZ) for adult patients with recurrent glioblastoma (GBM).","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Nausea; Tolerability; Internal medicine; Temozolomide; Oncology; Cancer; Bevacizumab; Pharmacology; Gastroenterology; Adverse effect; Chemotherapy","score_opus":0.29302632920703436,"score_gpt":0.5846921575951359,"score_spread":0.29166582838810157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2722759707","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924723,0.000047461293,0.00009382258,0.0021599857,0.003353493,0.0013842266,0.000048077658,0.000010069513,0.00043058474],"genre_scores_gemma":[0.99746174,0.00016285162,0.0007912014,0.0008815081,0.000528501,0.000034448538,0.000007707102,0.000032521115,0.000099553756],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99328494,0.0017849198,0.0035623824,0.0004658249,0.00044385748,0.0004580784],"domain_scores_gemma":[0.98764426,0.0029899552,0.006340353,0.00039611466,0.0021809342,0.0004483856],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0055323816,0.00032541153,0.0020466303,0.00022531104,0.000403241,0.000028507882,0.0008071174,0.0006578359,0.0000845498],"category_scores_gemma":[0.0037909083,0.00020670066,0.00035086134,0.00015490506,0.00089361996,0.00036264115,0.00019098257,0.0020674712,0.0000047868352],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.09277454,0.07311734,0.66163576,0.000043447013,0.0008819151,0.00020930915,0.00033260538,0.00001531069,0.000029359491,0.00011301449,0.0031171408,0.16773026],"study_design_scores_gemma":[0.14742905,0.21757665,0.60151,0.00016126371,0.00073421036,0.000032275228,0.00045619803,0.0005341942,0.00013160169,0.00018839852,0.030946488,0.00029968657],"about_ca_topic_score_codex":0.000023035069,"about_ca_topic_score_gemma":0.0008910468,"teacher_disagreement_score":0.16743056,"about_ca_system_score_codex":0.00013243842,"about_ca_system_score_gemma":0.0008173445,"threshold_uncertainty_score":0.8982249},"labels":[],"label_agreement":null},{"id":"W2732470776","doi":"10.1093/annonc/mdx302.002","title":"Phase 1b/II study of cancer stemness inhibitor napabucasin in combination with FOLFIRI +/− bevacizumab (bev) in metastatic colorectal cancer (mCRC) patients (pts)","year":2017,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Medicine; FOLFIRI; Internal medicine; Cancer; Colorectal cancer; Gastroenterology; Oncology; Combination therapy; Irinotecan","score_opus":0.2443052311328311,"score_gpt":0.5327082909976887,"score_spread":0.2884030598648576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2732470776","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957766,0.0003271753,0.0000018885406,0.00090446486,0.0009300512,0.001243127,0.00019091036,0.000009662818,0.0006161402],"genre_scores_gemma":[0.99893814,0.00031748932,0.000019955005,0.0002559632,0.000046988618,0.00030479187,0.000019721785,0.000022766983,0.000074189484],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9975243,0.0006649341,0.00072310376,0.00039912201,0.00024974946,0.00043877983],"domain_scores_gemma":[0.9979872,0.00022796767,0.0009771141,0.00023370769,0.0004614246,0.00011258351],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00069421995,0.0002636835,0.0008253245,0.00030403442,0.00025949406,0.000013311029,0.0004403305,0.00021122393,0.00023039112],"category_scores_gemma":[0.00009517964,0.00023354204,0.00006987396,0.0002447206,0.00042691373,0.0002754224,0.00019175309,0.00048293665,0.0000024201552],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008684257,0.07060647,0.796228,0.00015338424,0.0005725339,0.00014838493,0.0051884456,0.00015395554,0.0056257555,0.00010199882,0.00082255935,0.11171427],"study_design_scores_gemma":[0.11981753,0.036194704,0.77049464,0.00024434645,0.00036022486,0.0000054267894,0.0020103524,0.0010177796,0.061087206,0.00020777264,0.007981521,0.000578505],"about_ca_topic_score_codex":0.0028515174,"about_ca_topic_score_gemma":0.024815409,"teacher_disagreement_score":0.111135766,"about_ca_system_score_codex":0.00016745552,"about_ca_system_score_gemma":0.00033411666,"threshold_uncertainty_score":0.99297917},"labels":[],"label_agreement":null},{"id":"W2762459784","doi":"10.1021/acs.chemrestox.7b00227","title":"Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase κ","year":2017,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Institute of Cancer Research; National Institute of General Medical Sciences; Department of Biotechnology, Ministry of Science and Technology, India; Canadian Institutes of Health Research; Central Michigan University","keywords":"DNA polymerase; DNA; DNA damage; DNA replication; Processivity; DNA polymerase delta; DNA adduct; Polymerase; Biology; Molecular biology; Chemistry; Genetics; Polymerase chain reaction; Gene; Reverse transcriptase","score_opus":0.33596491655728566,"score_gpt":0.5320840848448136,"score_spread":0.19611916828752796,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2762459784","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98399675,0.00017676191,0.00003802017,0.0056098574,0.000373399,0.00064999977,0.0001544787,0.000045409997,0.008955304],"genre_scores_gemma":[0.99790865,0.000113416856,0.00010426613,0.0004654217,0.00027074158,0.0001845415,0.00008546011,0.00004242227,0.0008251066],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9958933,0.0009325073,0.00064316567,0.00094479474,0.00045235755,0.0011338516],"domain_scores_gemma":[0.99644274,0.00069067336,0.00035681162,0.0017766203,0.0002641193,0.0004690246],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0025488213,0.0003027729,0.00056463864,0.00027071967,0.0007683634,0.000059843158,0.0023209176,0.00082751835,0.001156742],"category_scores_gemma":[0.0014021123,0.00030777213,0.00014148856,0.0002463621,0.0021675676,0.00019980616,0.0013569798,0.0017759884,0.000068140536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048643863,0.0011242387,0.002517411,0.00007687036,0.0000656137,0.000086833534,0.00013416448,2.3699641e-7,0.9673704,0.012209662,0.014467337,0.0014607854],"study_design_scores_gemma":[0.0027742798,0.00036041165,0.0038049885,0.000040881227,0.000024266204,0.000011335319,0.00009860647,0.00017178674,0.9737831,0.012147851,0.006512866,0.00026964],"about_ca_topic_score_codex":0.00008706684,"about_ca_topic_score_gemma":0.00004427094,"teacher_disagreement_score":0.0139118545,"about_ca_system_score_codex":0.000254927,"about_ca_system_score_gemma":0.00014629465,"threshold_uncertainty_score":0.9999374},"labels":[],"label_agreement":null},{"id":"W2770181257","doi":"10.1186/s12870-017-1148-6","title":"Involvement of LeMDR, an ATP-binding cassette protein gene, in shikonin transport and biosynthesis in Lithospermum erythrorhizon","year":2017,"lang":"en","type":"article","venue":"BMC Plant Biology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Program for Changjiang Scholars and Innovative Research Team in University; Program for New Century Excellent Talents in University; Brock University; National Natural Science Foundation of China","keywords":"ATP-binding cassette transporter; Biology; Biochemistry; Biosynthesis; Methyl jasmonate; Elicitor; Naphthoquinone; Yeast; Cell biology; Gene; Transporter; Botany","score_opus":0.18647376179653097,"score_gpt":0.4112492224857286,"score_spread":0.22477546068919763,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2770181257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978396,0.00026303728,0.000019754896,0.00029674722,0.000266836,0.00048902095,0.00052306574,0.000016679121,0.0002852433],"genre_scores_gemma":[0.9987802,0.0002778541,0.00049624423,0.00013398551,0.000062085106,0.000048398048,0.00012203848,0.00001402118,0.00006520357],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99831516,0.0003430875,0.00042281838,0.00043283254,0.000059621987,0.00042650013],"domain_scores_gemma":[0.99925554,0.000111264366,0.00024762377,0.00025459033,0.000021814047,0.00010914027],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008376875,0.00021939524,0.00043279203,0.00020365945,0.0001751806,0.000013225999,0.0003372034,0.00036839995,0.00009304038],"category_scores_gemma":[0.00003970066,0.00019704526,0.00005148,0.00006565903,0.00037295424,0.00013388618,0.00008359836,0.0003584087,0.000005306291],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032725523,0.00024631844,0.65849054,0.000058097845,0.000027773487,0.00007434096,0.00029206873,0.0000021424162,0.33889696,0.00061305106,0.000010032246,0.0009613866],"study_design_scores_gemma":[0.0020374097,0.0003026474,0.71459514,0.00009667727,0.000035014113,0.000028972188,0.00016676821,0.00046380702,0.2784979,0.00023219266,0.0032239228,0.00031951678],"about_ca_topic_score_codex":0.00086021976,"about_ca_topic_score_gemma":0.0059362296,"teacher_disagreement_score":0.060399055,"about_ca_system_score_codex":0.000052255276,"about_ca_system_score_gemma":0.000072270515,"threshold_uncertainty_score":0.80352724},"labels":[],"label_agreement":null},{"id":"W2783414972","doi":"10.18632/oncotarget.24157","title":"Bufalin inhibits gastric cancer invasion and metastasis by down-regulating Wnt/ASCL2 expression","year":2018,"lang":"en","type":"article","venue":"Oncotarget","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Vancouver Biotech (Canada)","funders":"Health System Independent Innovation Science Foundation of Shanghai Putuo District","keywords":"Cancer; Wnt signaling pathway; Metastasis; Cancer research; Medicine; Oncology; Biology; Bioinformatics; Internal medicine; Pathology; Signal transduction; Cell biology","score_opus":0.10968019375539541,"score_gpt":0.4254467561811352,"score_spread":0.3157665624257398,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2783414972","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99261016,0.002745674,0.00011586212,0.0010494123,0.0008822712,0.0002259608,0.0001549315,0.000068851856,0.002146853],"genre_scores_gemma":[0.9947853,0.0009013363,0.00093166425,0.0014003688,0.000522854,0.00003182821,0.00004951482,0.000027389055,0.0013497124],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99837655,0.0002839512,0.0002856316,0.00043742213,0.00017693809,0.00043951662],"domain_scores_gemma":[0.9992188,0.00011303169,0.00016955973,0.00013760697,0.00010763686,0.00025335507],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00041198832,0.00024978438,0.00027504555,0.000087695145,0.00049253966,0.000039077186,0.0001630007,0.00021629319,0.002702435],"category_scores_gemma":[0.000036544283,0.00021222937,0.00006554348,0.00021875808,0.00027846236,0.00015708931,0.00019147263,0.00038047272,0.00008896695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001798092,0.00019561635,0.054799154,0.000034153996,0.000072295494,0.000006745162,0.00032122797,0.000008018564,0.7920131,0.000048246053,0.14325711,0.009064487],"study_design_scores_gemma":[0.0015366682,0.00018767618,0.006746596,0.00007018707,0.00010455902,0.000015286496,0.00008854022,0.000533976,0.6700207,0.00018561284,0.3201939,0.00031629213],"about_ca_topic_score_codex":0.00013556048,"about_ca_topic_score_gemma":0.00006503104,"teacher_disagreement_score":0.17693676,"about_ca_system_score_codex":0.00006107866,"about_ca_system_score_gemma":0.000044081353,"threshold_uncertainty_score":0.99820924},"labels":[],"label_agreement":null},{"id":"W2787038964","doi":"10.1016/s2468-1253(18)30009-8","title":"Napabucasin versus placebo in refractory advanced colorectal cancer: a randomised phase 3 trial","year":2018,"lang":"en","type":"article","venue":"The Lancet. Gastroenterology & hepatology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":168,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; University of Alberta; University of Toronto; Ottawa Hospital; BC Cancer Agency; Princess Margaret Cancer Centre; University of Ottawa; University of British Columbia","funders":"Canadian Cancer Society Research Institute; Boston Biomedical; Cancer Research Institute","keywords":"Placebo; Medicine; Colorectal cancer; Refractory (planetary science); Internal medicine; Oncology; Clinical trial; Cancer; Alternative medicine; Biology; Pathology","score_opus":0.11179583937330008,"score_gpt":0.4385704081685156,"score_spread":0.32677456879521555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2787038964","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98142624,0.00039761903,0.00011141156,0.0035797504,0.01082841,0.0017426093,0.00012808599,0.00013042391,0.0016554324],"genre_scores_gemma":[0.9905947,0.0005280071,0.00009518738,0.005465797,0.0022633981,0.0008270562,0.00004449244,0.000048358263,0.0001329886],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99393934,0.002549633,0.0008456919,0.0008459533,0.0001818265,0.0016375545],"domain_scores_gemma":[0.99772054,0.00093091273,0.00048728083,0.00045369563,0.00015326882,0.00025428005],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0012386556,0.0005262199,0.0013333089,0.0002429536,0.00045765252,0.000024132793,0.0009009891,0.0005967234,0.0015534303],"category_scores_gemma":[0.00013033151,0.00043969927,0.0002532475,0.0002831349,0.0019643486,0.00013827044,0.00019250973,0.0016738944,0.00015397093],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.87738806,0.0013383044,0.080902845,0.00001795871,0.00050499977,0.0002264854,0.00043449903,0.000012653234,0.022066182,0.00008027277,0.011126783,0.0059009446],"study_design_scores_gemma":[0.8503135,0.009334443,0.0061805034,0.000021747946,0.00030255687,0.00016994879,0.00016727265,0.002618589,0.0039333124,0.00010943316,0.1264537,0.00039501284],"about_ca_topic_score_codex":0.000110791494,"about_ca_topic_score_gemma":0.005474369,"teacher_disagreement_score":0.11532692,"about_ca_system_score_codex":0.00028262404,"about_ca_system_score_gemma":0.00020968221,"threshold_uncertainty_score":0.99980545},"labels":[],"label_agreement":null},{"id":"W2792644844","doi":"10.1016/j.ejmech.2018.03.043","title":"New cytokinin derivatives possess UVA and UVB photoprotective effect on human skin cells and prevent oxidative stress","year":2018,"lang":"en","type":"article","venue":"European Journal of Medicinal Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministerstvo Školství, Mládeže a Tělovýchovy; University of Ottawa","keywords":"Chemistry; HaCaT; Juglone; Bioassay; Oxidative stress; Kinetin; Biological activity; Antioxidant; Singlet oxygen; Cytokinin; Reactive oxygen species; Stereochemistry; Photoprotection; Biochemistry; In vitro; Organic chemistry; Oxygen; Tissue culture","score_opus":0.0641232843174508,"score_gpt":0.396574707801742,"score_spread":0.3324514234842912,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792644844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99052495,0.00041612278,0.00024675918,0.0001967511,0.00027410086,0.00014290887,0.000019006804,0.000010548403,0.008168855],"genre_scores_gemma":[0.9977038,0.00009387238,0.00014408224,0.00026855062,0.0012751363,0.0000010390122,0.000002501121,0.00002298017,0.00048803462],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982886,0.0006774602,0.0003406497,0.0002472237,0.00021590144,0.00023016873],"domain_scores_gemma":[0.9987733,0.00022378768,0.0004159351,0.00009863225,0.00012802315,0.00036033956],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010137884,0.00024329433,0.00032563912,0.000049785056,0.00023043487,0.000028139852,0.00022340518,0.00007234587,0.00046193838],"category_scores_gemma":[0.00008813944,0.00018619822,0.0000624914,0.000078918856,0.0005168313,0.0000798768,0.00009960403,0.00087646896,0.000007384455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009119836,0.00017596156,0.0019828123,0.00012128039,0.00028134484,0.00049248885,0.0016283504,0.0000012893488,0.9750881,0.000009823415,0.0017958422,0.017510707],"study_design_scores_gemma":[0.0027223628,0.0027395105,0.013569563,0.00037275426,0.00013651531,0.0002569917,0.0004508325,0.00000897219,0.97533095,0.000052442523,0.0041825194,0.00017661123],"about_ca_topic_score_codex":0.0000042352435,"about_ca_topic_score_gemma":6.957732e-7,"teacher_disagreement_score":0.017334096,"about_ca_system_score_codex":0.000040909687,"about_ca_system_score_gemma":0.00004677642,"threshold_uncertainty_score":0.7592943},"labels":[],"label_agreement":null},{"id":"W2804014342","doi":"10.1016/j.etap.2018.05.006","title":"Hepatoprotective effect of lawsone on rifampicin-isoniazid induced hepatotoxicity in in vitro and in vivo models","year":2018,"lang":"en","type":"article","venue":"Environmental Toxicology and Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Population and Public Health; King Saud University","keywords":"Lawsone; Pharmacology; In vivo; Hepatoprotection; Lawsonia inermis; Chemistry; Biochemistry; Rifampicin; ABTS; Plumbagin; In vitro; Biology; Antioxidant; Traditional medicine; Medicine; Glutathione; Antibiotics; Enzyme; Botany; Biotechnology; DPPH; Organic chemistry","score_opus":0.055671111941370796,"score_gpt":0.37155282744909757,"score_spread":0.31588171550772676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2804014342","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964732,0.00036913544,0.000005318238,0.0002625053,0.00057076226,0.0011331127,0.00007987302,0.000016703681,0.0010893793],"genre_scores_gemma":[0.9975563,0.0006015306,0.000037223006,0.0014390761,0.000104363244,0.00017969363,0.0000060592674,0.000024994646,0.000050703242],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99659264,0.0014407963,0.00052858336,0.00068481604,0.000112273934,0.0006408932],"domain_scores_gemma":[0.99883956,0.00068265427,0.00017413178,0.00012796868,0.0000066863727,0.00016902885],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010172687,0.00039034715,0.00075085124,0.00043983036,0.00012674902,0.0000051454736,0.00019031632,0.00065902766,0.0007467797],"category_scores_gemma":[0.000022736678,0.0003821792,0.000056249934,0.0002432999,0.0011184615,0.00015318941,0.000224862,0.0011849066,0.0000144846035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007021526,0.0009737847,0.22081715,0.000041667514,0.000058742695,0.0001440593,0.0006729891,0.000058846425,0.76652265,0.00006323115,0.000035449633,0.003589898],"study_design_scores_gemma":[0.008312579,0.0023679454,0.108365044,0.00002247902,0.00004210688,0.000036940866,0.0000833775,0.006113491,0.8735164,0.00037952542,0.0004563986,0.00030372816],"about_ca_topic_score_codex":0.0001079976,"about_ca_topic_score_gemma":0.00023841683,"teacher_disagreement_score":0.11245211,"about_ca_system_score_codex":0.0002246601,"about_ca_system_score_gemma":0.000026234213,"threshold_uncertainty_score":0.999863},"labels":[],"label_agreement":null},{"id":"W2809783990","doi":"10.1002/anie.201804351","title":"Total Synthesis Establishes the Biosynthetic Pathway to the Naphterpin and Marinone Natural Products","year":2018,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Australian Research Council; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Biosynthesis; Halogenation; Total synthesis; Stereochemistry; Biomimetic synthesis; Enzyme; Chlorine; Biochemistry; Organic chemistry","score_opus":0.05349005272961124,"score_gpt":0.35123780660955617,"score_spread":0.2977477538799449,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2809783990","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91131026,0.00033856768,0.00020514257,0.06592547,0.009849979,0.00045097794,0.00025997826,0.00007477778,0.011584871],"genre_scores_gemma":[0.99102813,0.00006678885,0.00006707849,0.0027471362,0.003992866,0.00007499553,0.000040602776,0.000012193336,0.001970223],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906737,0.00008566191,0.0001605853,0.0002765152,0.0002026796,0.00020718727],"domain_scores_gemma":[0.9992045,0.00026821336,0.000078883764,0.0001490532,0.00023753924,0.00006179838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036532906,0.00014735504,0.000098441975,0.0000548301,0.00036575107,0.00009154325,0.0003045257,0.000080179976,0.0005076227],"category_scores_gemma":[0.0002785144,0.000088670706,0.00004621421,0.00014671085,0.00034147163,0.0001768901,0.00016871927,0.0002740508,0.00009994746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00063430733,0.00036554324,0.0026079102,0.000041716336,0.00046801026,0.00002721805,0.0018027205,0.000003649991,0.8047453,0.00190216,0.12869196,0.058709472],"study_design_scores_gemma":[0.00016916245,0.000034295845,0.0071099075,0.000021383208,0.000032447864,0.00006458341,0.00013600804,0.0001444767,0.77445525,0.0001566888,0.21756472,0.00011105473],"about_ca_topic_score_codex":0.000049391285,"about_ca_topic_score_gemma":0.000036622507,"teacher_disagreement_score":0.088872775,"about_ca_system_score_codex":0.00005220834,"about_ca_system_score_gemma":0.000028203247,"threshold_uncertainty_score":0.5558113},"labels":[],"label_agreement":null},{"id":"W2886059997","doi":"10.2298/jsc180627062j","title":"Alkylamino and aralkylamino derivatives of avarone and its mimetic as selective agents against non-small cell lung cancer cells, their antibacterial and antifungal potential","year":2018,"lang":"en","type":"article","venue":"Journal of the Serbian Chemical Society","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"HaCaT; Antimicrobial; Chemistry; Cancer cell; Moiety; Quinone; Cytotoxicity; Multiple drug resistance; Apoptosis; Cytotoxic T cell; Stereochemistry; Antibiotics; Biochemistry; Cancer; Biology; In vitro; Organic chemistry","score_opus":0.03465660977414752,"score_gpt":0.33563433954629585,"score_spread":0.3009777297721483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886059997","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99684864,0.0015216691,0.00002193288,0.0003933228,0.0007672012,0.00022757705,0.0000729707,0.0000054817865,0.00014118067],"genre_scores_gemma":[0.9957498,0.002622796,0.00022282351,0.0007109739,0.0005351809,0.0000016622639,0.0000016183976,0.000019149253,0.00013603024],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99872845,0.00017115686,0.00038150378,0.00024447867,0.00015145954,0.00032297117],"domain_scores_gemma":[0.99888694,0.000102354265,0.00049696106,0.00008369765,0.000237998,0.00019204734],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033756517,0.00024414939,0.00040156976,0.000027147264,0.00026502402,0.000035935343,0.0002452762,0.00026282523,0.00008725466],"category_scores_gemma":[0.000021884287,0.00017121808,0.00018977067,0.00013055121,0.0006206138,0.00013448064,0.00025596804,0.00063536345,7.1603694e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026845714,0.00019784966,0.013365303,0.00017666807,0.00044867775,0.0000055028436,0.0021600972,0.0000028103777,0.98137194,0.000004136984,0.0013638284,0.00063475093],"study_design_scores_gemma":[0.0020023764,0.00015791002,0.044649843,0.00010354338,0.00028640064,0.000047738493,0.00031355573,0.0020120654,0.9497775,0.000052313546,0.00041289412,0.00018387254],"about_ca_topic_score_codex":0.000008441936,"about_ca_topic_score_gemma":0.0000012490913,"teacher_disagreement_score":0.03159443,"about_ca_system_score_codex":0.00005227524,"about_ca_system_score_gemma":0.000096068434,"threshold_uncertainty_score":0.6982071},"labels":[],"label_agreement":null},{"id":"W2888129406","doi":"10.1139/cjc-2018-0145","title":"Synthesis, characterization, and anticancer evaluation of some new <i>N</i>1-(anthraquinon-2-yl) amidrazone derivatives","year":2018,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Piperazine; Bromide; K562 cells; In vitro; Amine gas treating; Cell culture; Chloride; Stereochemistry; Chronic myelogenous leukemia; Combinatorial chemistry; Proton NMR; Cancer cell lines; Cancer cell; Leukemia; Organic chemistry; Biochemistry; Cancer","score_opus":0.09868938369453503,"score_gpt":0.38783945076575715,"score_spread":0.28915006707122215,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2888129406","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961753,0.0011971997,0.00013001313,0.0010786862,0.00044434034,0.00006969287,0.00005343337,0.0000030091494,0.0008483162],"genre_scores_gemma":[0.9983993,0.00028565852,0.00006381666,0.0002875631,0.0007819218,0.0000016249934,0.0000066805646,0.000010925553,0.0001624735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990967,0.00009662778,0.00031948226,0.00011741353,0.00016648206,0.00020331243],"domain_scores_gemma":[0.99848264,0.000070875416,0.0003493033,0.00008777823,0.0005458948,0.00046351287],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005508864,0.00011645423,0.00022215389,0.00006682054,0.00013361771,0.000020370464,0.0001621164,0.00013196691,0.0020552694],"category_scores_gemma":[0.0002487182,0.000111982474,0.000048467653,0.000110306915,0.00050712563,0.0001889057,0.000012837201,0.00020889095,0.0000033515203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000064769054,0.00003405542,0.030482644,0.000053604854,0.00017012602,0.000013410185,0.0004436497,0.000002578113,0.94608325,0.000039161212,0.0021722186,0.02044053],"study_design_scores_gemma":[0.0007690351,0.000046581703,0.0426649,0.000102260696,0.00018535473,0.00007983632,0.0001224306,0.00017213277,0.9332335,0.00021853349,0.022273267,0.00013214062],"about_ca_topic_score_codex":0.00010568097,"about_ca_topic_score_gemma":0.00011459063,"teacher_disagreement_score":0.020308388,"about_ca_system_score_codex":0.000082377264,"about_ca_system_score_gemma":0.0013987595,"threshold_uncertainty_score":0.99885696},"labels":[],"label_agreement":null},{"id":"W2888134140","doi":"10.1002/open.201800117","title":"SAHAquines, Novel Hybrids Based on SAHA and Primaquine Motifs, as Potential Cytostatic and Antiplasmodial Agents","year":2018,"lang":"en","type":"article","venue":"ChemistryOpen","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Hrvatska Zaklada za Znanost","keywords":"Primaquine; Chemistry; Hydroxylamine; Combinatorial chemistry; Acetylation; Stereochemistry; Hydrolysis; Antimalarial Agent; Plasmodium falciparum; Biochemistry; Biology; Malaria; Chloroquine","score_opus":0.08593371108747677,"score_gpt":0.4121352944277741,"score_spread":0.3262015833402973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2888134140","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898815,0.000103638595,0.00015398469,0.0005987319,0.0005020585,0.0002968,0.00013901225,0.000048445163,0.008275842],"genre_scores_gemma":[0.9952532,0.000075907374,0.00027256992,0.002717079,0.00044503313,0.00001052144,0.000091993716,0.000029284662,0.0011043987],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986202,0.00005812448,0.00023765638,0.00051408727,0.00017585873,0.00039405134],"domain_scores_gemma":[0.99919844,0.00009708963,0.00010954543,0.00020863867,0.00008831185,0.0002979661],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00025131705,0.00029107998,0.0002786204,0.000049942573,0.0003450346,0.00008074091,0.00022871162,0.00017143691,0.0011132215],"category_scores_gemma":[0.00008173215,0.0002758741,0.000050858056,0.000102941856,0.0005725713,0.00009426366,0.00018429304,0.00034862646,0.00007555609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014522598,0.00076920685,0.020240188,0.00020676105,0.00018604335,0.0001471902,0.00012472065,0.000030497453,0.9531899,0.00005427744,0.01635472,0.0072442484],"study_design_scores_gemma":[0.010628334,0.0008369974,0.04029033,0.00012089322,0.00029922728,0.00024861493,0.00007774811,0.02918045,0.84330046,0.00020306953,0.07396206,0.0008518163],"about_ca_topic_score_codex":0.000022658765,"about_ca_topic_score_gemma":0.0000019363613,"teacher_disagreement_score":0.10988944,"about_ca_system_score_codex":0.000040951934,"about_ca_system_score_gemma":0.000081021215,"threshold_uncertainty_score":0.99996936},"labels":[],"label_agreement":null},{"id":"W2889685701","doi":"10.1200/jco.2016.34.15_suppl.5578","title":"A phase Ib/II study of cancer stemness inhibitor napabucasin (BB608) combined with weekly paclitaxel in platinum-resistant ovarian cancer.","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; St Mary's Hospital Centre","funders":"","keywords":"Medicine; Ovarian cancer; Paclitaxel; Cancer; Cancer research; Oncology; Internal medicine","score_opus":0.2935424440650372,"score_gpt":0.5664334602611045,"score_spread":0.2728910161960673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2889685701","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9884862,0.00050362485,0.000029074285,0.0067046247,0.0031005512,0.0005796778,0.00010296353,0.00001109191,0.00048222154],"genre_scores_gemma":[0.9971019,0.0006010145,0.00014028272,0.0007722516,0.00082068663,0.000044404835,9.918131e-7,0.000028819064,0.0004896713],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9937961,0.002020986,0.0029532746,0.00036623265,0.0003952638,0.0004681245],"domain_scores_gemma":[0.9931246,0.002623287,0.003006581,0.00020900735,0.0006087729,0.00042774246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0035510568,0.00029866956,0.0018960015,0.00022821876,0.00014769433,0.000009354911,0.00046542275,0.00054131524,0.00090988685],"category_scores_gemma":[0.0005084166,0.00017442326,0.00022733651,0.0003492262,0.0005545792,0.00021320963,0.00013984783,0.0013673038,0.000004231345],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.11567008,0.058628496,0.5928597,0.00008798665,0.0023802198,0.0018426605,0.0015055157,0.00005884029,0.03222269,0.00025823704,0.005034721,0.18945089],"study_design_scores_gemma":[0.24664605,0.19839305,0.45367354,0.0008767068,0.0015232414,0.0000818935,0.002789253,0.00016106458,0.0053924094,0.0003757094,0.089346714,0.0007403905],"about_ca_topic_score_codex":0.0003098071,"about_ca_topic_score_gemma":0.0042765485,"teacher_disagreement_score":0.1887105,"about_ca_system_score_codex":0.00029595636,"about_ca_system_score_gemma":0.0015958116,"threshold_uncertainty_score":0.9962623},"labels":[],"label_agreement":null},{"id":"W2890388049","doi":"10.1200/jco.2017.35.15_suppl.3529","title":"Phase 1b/II study of cancer stemness inhibitor napabucasin (BBI-608) in combination with FOLFIRI +/- bevacizumab (bev) in metastatic colorectal cancer (mCRC) patients (pts).","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Medicine; FOLFIRI; Bevacizumab; Internal medicine; Colorectal cancer; Cancer; Oncology; Combination therapy; Irinotecan; Gastroenterology; Pharmacology; Chemotherapy","score_opus":0.3085729750230846,"score_gpt":0.5868428381078282,"score_spread":0.2782698630847436,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2890388049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933388,0.00030412746,0.0000066053035,0.0012613833,0.0038864762,0.000849577,0.000057296194,0.0000053345957,0.00029040093],"genre_scores_gemma":[0.9986438,0.00045901845,0.000085688254,0.0003597047,0.00028395813,0.00006560441,0.0000042822785,0.000024626197,0.00007332561],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9943734,0.0017931338,0.0026270153,0.00035312175,0.00044064084,0.00041271994],"domain_scores_gemma":[0.9933691,0.0012571181,0.004164449,0.00020627202,0.0007301108,0.00027296157],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0031986802,0.00028132997,0.0017643764,0.0003037626,0.00026419718,0.000024227225,0.00062065053,0.00039783545,0.0002603493],"category_scores_gemma":[0.0008450465,0.00021428429,0.00020509203,0.00022235738,0.0005355958,0.0004159616,0.0001956968,0.0017768969,0.0000027574106],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01697901,0.075789854,0.7941222,0.000051621235,0.00067270873,0.00047223706,0.0011910817,0.00012682211,0.0004934232,0.0000253137,0.0004978893,0.109577805],"study_design_scores_gemma":[0.14472374,0.040213767,0.805439,0.00019086742,0.00059845473,0.000015344725,0.0008155912,0.0006573003,0.0012803002,0.000115452596,0.0056722513,0.00027795142],"about_ca_topic_score_codex":0.000717649,"about_ca_topic_score_gemma":0.014193005,"teacher_disagreement_score":0.12774473,"about_ca_system_score_codex":0.0004189998,"about_ca_system_score_gemma":0.0011441682,"threshold_uncertainty_score":0.87382597},"labels":[],"label_agreement":null},{"id":"W2890697824","doi":"10.1200/jco.2016.34.15_suppl.3564","title":"Phase 1b extension study of cancer stemness inhibitor BB608 (napabucasin) administered in combination with FOLFIRI +/- bevacizumab (Bev) in patients (pts) with advanced colorectal cancer (CRC).","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Medicine; FOLFIRI; Bevacizumab; Internal medicine; Colorectal cancer; Gastroenterology; Adverse effect; Irinotecan; Cancer; Oncology; Surgery; Chemotherapy","score_opus":0.20684317347930398,"score_gpt":0.5463825819132724,"score_spread":0.3395394084339684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2890697824","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956406,0.00022104921,0.00001864693,0.0010625726,0.0020213502,0.0008891489,0.000042367563,0.000007584301,0.00009669246],"genre_scores_gemma":[0.998714,0.0004644191,0.000100371064,0.00037831496,0.00019841663,0.00006028095,0.0000029159746,0.000028037119,0.000053233132],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9950501,0.0015033911,0.0022290603,0.0003997932,0.0004276971,0.00039001307],"domain_scores_gemma":[0.9946307,0.0014789698,0.0025718668,0.00014817658,0.00089567126,0.00027459496],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016721283,0.0002794527,0.0014950045,0.0002888478,0.000072159455,0.000007861043,0.000300681,0.00042853729,0.00018639702],"category_scores_gemma":[0.00034688145,0.0001651911,0.00013081776,0.00037025928,0.00039663533,0.00034109858,0.00008272786,0.0010234358,0.0000024966548],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.06885166,0.048359364,0.67801017,0.000029362976,0.00030514432,0.00033228289,0.00043168696,0.000055016495,0.001925703,0.000009307051,0.00016117563,0.20152912],"study_design_scores_gemma":[0.18644425,0.07360409,0.73315126,0.0004147984,0.00027708945,0.000018106168,0.00046818022,0.00009156113,0.0024925526,0.000028741875,0.0027610254,0.00024833984],"about_ca_topic_score_codex":0.00008551061,"about_ca_topic_score_gemma":0.004020323,"teacher_disagreement_score":0.20128077,"about_ca_system_score_codex":0.00046833677,"about_ca_system_score_gemma":0.0010362224,"threshold_uncertainty_score":0.67362976},"labels":[],"label_agreement":null},{"id":"W2891033814","doi":"10.1200/jco.2017.35.15_suppl.9052","title":"A phase 1b/2 study of napabucasin with weekly paclitaxel in advanced, previously treated non-squamous non-small cell lung cancer.","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St Mary's Hospital Centre; Ottawa Hospital; University of Ottawa","funders":"","keywords":"Medicine; Lung cancer; Internal medicine; Cancer; Oncology; Taxane; Paclitaxel; Breast cancer","score_opus":0.23669700405385305,"score_gpt":0.5656816634140758,"score_spread":0.3289846593602227,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891033814","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924311,0.00066990795,0.000047998583,0.00089931104,0.0018048041,0.0009525639,0.000025734149,0.00000772804,0.003160865],"genre_scores_gemma":[0.9968543,0.0011528278,0.0004109781,0.0004898123,0.00051542075,0.000036191992,0.0000017323979,0.0000324875,0.0005062372],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9951574,0.0011125995,0.0025269575,0.00040288613,0.00026505886,0.0005350797],"domain_scores_gemma":[0.99230313,0.0016385972,0.004638338,0.00041066707,0.00053517165,0.0004741059],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0033202027,0.00032992926,0.0020317466,0.00019055637,0.00024663942,0.000025603871,0.000891904,0.00056749943,0.00016990145],"category_scores_gemma":[0.0005883789,0.00024164308,0.00033895887,0.0001546027,0.00050684647,0.00026186812,0.00015831951,0.002204031,0.0000056229283],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01881865,0.057487316,0.8520978,0.000121975914,0.0006638316,0.002573091,0.001185667,0.00020298855,0.002726772,0.0000051016855,0.001560162,0.06255664],"study_design_scores_gemma":[0.2029681,0.09298329,0.67679536,0.0003365496,0.0019768013,0.00015190554,0.0021387152,0.0022962727,0.003234927,0.00004154104,0.016474599,0.00060192967],"about_ca_topic_score_codex":0.00031324817,"about_ca_topic_score_gemma":0.0016992075,"teacher_disagreement_score":0.18414946,"about_ca_system_score_codex":0.00018947515,"about_ca_system_score_gemma":0.0011515865,"threshold_uncertainty_score":0.98539186},"labels":[],"label_agreement":null},{"id":"W2891770034","doi":"10.3390/pharmaceutics10030144","title":"DOX-Vit D, a Novel Doxorubicin Delivery Approach, Inhibits Human Osteosarcoma Cell Proliferation by Inducing Apoptosis While Inhibiting Akt and mTOR Signaling Pathways","year":2018,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Doxorubicin; PI3K/AKT/mTOR pathway; Apoptosis; Protein kinase B; Cell growth; Cancer research; Cancer cell; MTT assay; Chemistry; Signal transduction; Pharmacology; Biology; Cancer; Cell biology; Chemotherapy; Biochemistry","score_opus":0.16720889361291086,"score_gpt":0.37828541739855154,"score_spread":0.21107652378564068,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891770034","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907143,0.00080814346,0.0016395851,0.00026125566,0.0006784859,0.0008939574,0.0002830082,0.00021414181,0.0045070997],"genre_scores_gemma":[0.9936291,0.00013972579,0.0017151054,0.002754373,0.0011175927,0.00007799534,0.00020545171,0.000092786446,0.0002678618],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966612,0.0003936933,0.0007412935,0.00087407505,0.00037491444,0.0009548172],"domain_scores_gemma":[0.9982864,0.00021097556,0.00041994886,0.00026591498,0.00032345738,0.0004932764],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0010875238,0.0005777678,0.00048578173,0.00023800576,0.0014628641,0.00019899361,0.00039931876,0.0004540412,0.0002394179],"category_scores_gemma":[0.00005264741,0.0005985,0.00012728239,0.00044633466,0.0004866543,0.00046977375,0.0005024429,0.0012597966,0.000054328306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017352677,0.0011019977,0.00637414,0.00021849542,0.0001327577,0.000005912294,0.0022472194,0.00002913199,0.9822601,0.00013360912,0.003693724,0.0036293515],"study_design_scores_gemma":[0.003655198,0.00030724602,0.00007361407,0.000069600836,0.00028810196,0.00003482973,0.0007212493,0.011293329,0.9657978,0.00006365543,0.017010882,0.0006844938],"about_ca_topic_score_codex":0.000034629466,"about_ca_topic_score_gemma":0.000006806077,"teacher_disagreement_score":0.016462335,"about_ca_system_score_codex":0.0001507735,"about_ca_system_score_gemma":0.00009008897,"threshold_uncertainty_score":0.9998371},"labels":[],"label_agreement":null},{"id":"W2892205551","doi":"10.1200/jco.2017.35.15_suppl.5548","title":"A phase 1b/2 study of napabucasin with weekly paclitaxel in advanced, previously treated platinum resistant ovarian cancer.","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St Mary's Hospital Centre","funders":"","keywords":"Medicine; Taxane; Internal medicine; Ovarian cancer; Cancer; Paclitaxel; Oncology; Tolerability; Adverse effect; Gastroenterology; Breast cancer","score_opus":0.3722542817996232,"score_gpt":0.6021979240114069,"score_spread":0.2299436422117837,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2892205551","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925289,0.0004249114,0.000013116983,0.0021506352,0.0013637394,0.0005650563,0.00003429596,0.000007804829,0.002911547],"genre_scores_gemma":[0.99764925,0.0006953623,0.00045597806,0.00038680734,0.00041626717,0.000019562081,0.0000015071313,0.00002197518,0.00035330118],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9949378,0.0015602167,0.0024835442,0.00032462864,0.0002825998,0.0004112349],"domain_scores_gemma":[0.992812,0.0014584617,0.0045389817,0.00036245576,0.00045659742,0.0003715165],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003901729,0.00024876095,0.0017493495,0.00015768743,0.0002387566,0.000022740927,0.00068559765,0.00044995223,0.00024466254],"category_scores_gemma":[0.0012508566,0.00017569821,0.00021448125,0.00013968292,0.0005724018,0.00026990855,0.00011417098,0.0017704489,0.0000038857283],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.06727559,0.056565832,0.6887164,0.00005887289,0.001389885,0.0036614393,0.001057497,0.000086810964,0.004131398,0.00011905897,0.001361204,0.17557602],"study_design_scores_gemma":[0.14456193,0.096224904,0.70658904,0.0002897778,0.0009511357,0.00012495025,0.0016972837,0.00026571768,0.0008004297,0.00021864935,0.04791261,0.0003635494],"about_ca_topic_score_codex":0.00028761104,"about_ca_topic_score_gemma":0.0027333002,"teacher_disagreement_score":0.17521246,"about_ca_system_score_codex":0.0001610767,"about_ca_system_score_gemma":0.0009501183,"threshold_uncertainty_score":0.7691818},"labels":[],"label_agreement":null},{"id":"W2898642120","doi":"10.1002/prot.25607","title":"Validation of chemical genetics for the study of zipper‐interacting protein kinase signaling","year":2018,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canada Research Chairs; Canadian Institutes of Health Research; Alberta Innovates - Health Solutions","keywords":"Kinase; Phosphorylation; Biology; Cell biology; Biochemistry; Protein kinase A; Plasma protein binding; Docking (animal)","score_opus":0.07883189320233781,"score_gpt":0.37512213905784203,"score_spread":0.29629024585550423,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898642120","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898576,0.00005830258,0.007718509,0.00006275557,0.00042776868,0.0017302422,0.000051156352,0.000016419852,0.00007725626],"genre_scores_gemma":[0.99571824,0.000004513422,0.003914629,0.00007972707,0.00020062093,0.000039718077,0.000014593682,0.000008953193,0.000018989504],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907666,0.000063244086,0.00044090653,0.00011275762,0.00013876497,0.00016766362],"domain_scores_gemma":[0.99901664,0.0001276312,0.00038988484,0.00012851873,0.00028639226,0.00005093618],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032430992,0.0001389111,0.00017821927,0.000062053325,0.00021957008,0.000021880871,0.000120059456,0.000121845434,0.00012039964],"category_scores_gemma":[0.00010285655,0.00009256085,0.000048647915,0.00013649456,0.00018386998,0.000101688034,0.00006501839,0.00020761434,9.3656917e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000884117,0.0002698245,0.0049035223,0.0003696215,0.00024658497,1.9273661e-7,0.0029653076,0.00006607255,0.95295924,0.0002130118,0.000083481034,0.03703901],"study_design_scores_gemma":[0.001673557,0.0012682565,0.00067607715,0.000038168648,0.00020193178,0.0000049325477,0.0025491028,0.022932645,0.96871895,0.00027283427,0.0015319424,0.00013161771],"about_ca_topic_score_codex":0.0000072844286,"about_ca_topic_score_gemma":0.000003636801,"teacher_disagreement_score":0.036907397,"about_ca_system_score_codex":0.000014508358,"about_ca_system_score_gemma":0.000028010685,"threshold_uncertainty_score":0.3774522},"labels":[],"label_agreement":null},{"id":"W2900914615","doi":"10.1039/c8ra08138g","title":"Synthesis and biological study of acridine-based imidazolium salts","year":2018,"lang":"en","type":"article","venue":"RSC Advances","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Universiti Malaya","keywords":"Acridine; Acridine derivatives; Chemistry; Combinatorial chemistry; Organic chemistry; Stereochemistry","score_opus":0.15435379836892268,"score_gpt":0.445413633601306,"score_spread":0.2910598352323833,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2900914615","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99684054,0.0008211875,0.0000655623,0.00016605042,0.00048948504,0.00022116925,0.000028993893,0.000053698903,0.0013133291],"genre_scores_gemma":[0.99901396,0.00025394282,0.00019902362,0.00027854228,0.00019369196,0.00002494728,0.0000017520164,0.00000806742,0.000026087604],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901164,0.00022146227,0.0001988121,0.00026276705,0.00008386118,0.00022144109],"domain_scores_gemma":[0.9992127,0.0003901917,0.00011164391,0.00011439743,0.00008031187,0.00009079869],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024281323,0.00014139044,0.00024303584,0.00005706871,0.0001862942,0.000007534084,0.00015361067,0.00009482837,0.00030173972],"category_scores_gemma":[0.00009207886,0.00010639015,0.00003644174,0.00012378604,0.0004759008,0.00007873079,0.000064725464,0.00014885834,0.000018626446],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014956502,0.0030884205,0.86578155,0.00008812876,0.00022075338,0.000041950105,0.0007553282,0.00003716549,0.07570049,0.00043935858,0.001085283,0.051265903],"study_design_scores_gemma":[0.004229354,0.003792774,0.30530503,0.000056562058,0.00025921804,0.000016216387,0.0025268672,0.0018033243,0.5523646,0.0005909069,0.12839687,0.00065824785],"about_ca_topic_score_codex":0.000010015221,"about_ca_topic_score_gemma":0.00003120553,"teacher_disagreement_score":0.56047654,"about_ca_system_score_codex":0.000010726624,"about_ca_system_score_gemma":0.000017449265,"threshold_uncertainty_score":0.43384644},"labels":[],"label_agreement":null},{"id":"W2901553097","doi":"10.1039/c8ra07060a","title":"Facile synthesis of indole heterocyclic compounds based micellar nano anti-cancer drugs","year":2018,"lang":"en","type":"article","venue":"RSC Advances","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Population and Public Health; King Saud University","keywords":"Chemistry; Adduct; Indole test; Combinatorial chemistry; Micelle; Nano-; DNA adduct; Nuclear chemistry; Organic chemistry; Aqueous solution; Materials science","score_opus":0.07295990619165443,"score_gpt":0.4079932002418778,"score_spread":0.33503329405022336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901553097","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867722,0.0023863816,0.00020927994,0.00024679626,0.0012536017,0.00019741265,0.00026915726,0.00006807307,0.008597114],"genre_scores_gemma":[0.9969388,0.00088142743,0.00049693516,0.0007918442,0.00029576055,0.0000410346,0.000011734048,0.000022627286,0.0005198035],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985041,0.0002244862,0.00033301517,0.0003525439,0.00018844998,0.0003974098],"domain_scores_gemma":[0.99896383,0.00032546572,0.0002487369,0.0001940338,0.00013989146,0.00012804107],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020791889,0.00023912716,0.00039593526,0.0001088547,0.00029053958,0.00001637804,0.00035008744,0.00016527802,0.0015421446],"category_scores_gemma":[0.000030137979,0.00021586668,0.0001370739,0.00021926676,0.0006828516,0.00018449986,0.00007132179,0.00022173676,0.00012757783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036825132,0.0006261404,0.06693941,0.00020547265,0.00019996219,0.000006744923,0.0002682504,0.00012276419,0.8973867,0.000093133014,0.00300185,0.030781262],"study_design_scores_gemma":[0.000624976,0.00007847253,0.0013522018,0.000043538847,0.000061124134,0.0000014331488,0.00009046523,0.0005078847,0.708625,0.000052984662,0.28836673,0.00019515902],"about_ca_topic_score_codex":0.000022936922,"about_ca_topic_score_gemma":0.000019965015,"teacher_disagreement_score":0.2853649,"about_ca_system_score_codex":0.000045557124,"about_ca_system_score_gemma":0.00004293095,"threshold_uncertainty_score":0.9993706},"labels":[],"label_agreement":null},{"id":"W2902749844","doi":"10.1139/bcb-2018-0310","title":"Shikonin exerts antitumor activity by causing mitochondrial dysfunction in hepatocellular carcinoma through PKM2–AMPK–PGC1α signaling pathway","year":2018,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"AMPK; Mitochondrion; Oxidative stress; PKM2; Cell biology; Apoptosis; Reactive oxygen species; Citric acid cycle; Oxidative phosphorylation; Biology; Signal transduction; AMP-activated protein kinase; Cancer research; Chemistry; Glycolysis; Biochemistry; Protein kinase A; Phosphorylation; Pyruvate kinase; Metabolism","score_opus":0.06204302198010215,"score_gpt":0.33799718204574947,"score_spread":0.2759541600656473,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902749844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927192,0.0014897683,0.0003624487,0.00013775032,0.0014548858,0.00024298104,0.00011559126,0.000049296075,0.0034280866],"genre_scores_gemma":[0.9977033,0.00013039655,0.00012887195,0.0003695154,0.00083105324,0.000024451505,0.00012542706,0.000021817987,0.0006651659],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980114,0.00029424593,0.00032066315,0.00071359036,0.00008038929,0.000579705],"domain_scores_gemma":[0.9992665,0.00011804438,0.00018596092,0.0002021955,0.000070990434,0.00015627951],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026610258,0.0003417207,0.00037066068,0.000048207734,0.00037117334,0.000030698957,0.00015510358,0.00067510287,0.00034966995],"category_scores_gemma":[0.000030162026,0.00033282957,0.00008767833,0.00018358647,0.000630319,0.00010895457,0.00013065051,0.0005639383,0.000022262975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005048581,0.00030819848,0.05465316,0.00007962186,0.00003113505,0.000060129394,0.00016459324,9.632482e-7,0.9413989,0.000027447632,0.0014586176,0.0013123855],"study_design_scores_gemma":[0.0017430739,0.00018875135,0.00047576806,0.000021154683,0.00004063296,0.000033110122,0.00009569442,0.00056946813,0.964487,0.00010553246,0.031872332,0.00036747212],"about_ca_topic_score_codex":0.00014485169,"about_ca_topic_score_gemma":0.000009153469,"teacher_disagreement_score":0.054177392,"about_ca_system_score_codex":0.000084466476,"about_ca_system_score_gemma":0.00009410417,"threshold_uncertainty_score":0.9999124},"labels":[],"label_agreement":null},{"id":"W2906592541","doi":"10.1124/mol.118.114231","title":"S29434, a Quinone Reductase 2 Inhibitor: Main Biochemical and Cellular Characterization","year":2018,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Francis Xavier University","funders":"Natural Sciences and Engineering Research Council of Canada; Servier; Agence Nationale de la Recherche","keywords":"Reactive oxygen species; NAD+ kinase; Enzyme; Reductase; Quinone; Biochemistry; Cytosol; Chemistry; Cell biology; Biology","score_opus":0.04606515854142725,"score_gpt":0.37843262684054435,"score_spread":0.3323674682991171,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2906592541","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99219996,0.00053448445,0.0011713506,0.0017928719,0.002424628,0.000442822,0.000096927186,0.00011156599,0.001225385],"genre_scores_gemma":[0.991312,0.00013700052,0.00027127995,0.0064050355,0.0011625284,0.000054582237,0.00017899444,0.000044433174,0.00043413433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977667,0.0005309359,0.00035259398,0.0005991702,0.0001478179,0.0006028081],"domain_scores_gemma":[0.99913377,0.00005854234,0.00014662747,0.00017642272,0.00012803556,0.00035663],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003899246,0.0003188397,0.00031632325,0.00016356747,0.000303065,0.00003205239,0.00024184992,0.0003861705,0.0022979046],"category_scores_gemma":[0.00002823638,0.00033212022,0.00008864979,0.00027236965,0.0008994796,0.00011125492,0.00017762276,0.0005385033,0.00023398746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003617062,0.0003483583,0.00053376256,0.000033585064,0.00017326685,0.00033671528,0.0002396889,6.188055e-7,0.98302746,0.00032245094,0.012584666,0.0020377196],"study_design_scores_gemma":[0.0018874555,0.00025051573,0.00046397786,0.000007668649,0.0001881918,0.000100716425,0.000028672719,0.0006151003,0.88448787,0.000116169394,0.11153745,0.00031622715],"about_ca_topic_score_codex":0.000005779587,"about_ca_topic_score_gemma":8.0293614e-7,"teacher_disagreement_score":0.098952785,"about_ca_system_score_codex":0.00007044206,"about_ca_system_score_gemma":0.00006847706,"threshold_uncertainty_score":0.9999131},"labels":[],"label_agreement":null},{"id":"W2916947788","doi":"10.1039/c8ob02690d","title":"Synthesis and antitubercular activity of 1- and 3-substituted benzo[<i>g</i>]isoquinoline-5,10-diones","year":2019,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"Vlaamse regering; Universiteit Antwerpen; Agentschap voor Innovatie door Wetenschap en Technologie; Fonds Wetenschappelijk Onderzoek","keywords":"Chemistry; Isoquinoline; Stereochemistry; Potency; Cytotoxicity; Genotoxicity; Selectivity; In vitro; Biochemistry; Organic chemistry; Toxicity","score_opus":0.035516308777936996,"score_gpt":0.3378110388492294,"score_spread":0.30229473007129243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2916947788","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959051,0.0015302601,0.0005913077,0.00024420625,0.00012878518,0.00016866511,0.00005250236,0.000044023036,0.0013351666],"genre_scores_gemma":[0.9988348,0.0005768742,0.00008871116,0.00010175578,0.00005156922,0.000006199474,0.000014085284,0.000027200562,0.0002987865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99884313,0.00008620288,0.00021036879,0.0004350603,0.00014039144,0.0002848578],"domain_scores_gemma":[0.99925864,0.00008882945,0.00014009232,0.00026654266,0.00008023018,0.00016567273],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002012232,0.0002486585,0.00035707795,0.000038877948,0.00010749687,0.000021754771,0.00017401205,0.00031936803,0.0019057173],"category_scores_gemma":[0.0000703658,0.0002466375,0.000080505786,0.00019172492,0.00031405836,0.000088967274,0.00017725556,0.00025805781,0.00003592679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010545349,0.00018919348,0.0087053655,0.00036608148,0.00022040565,0.000040816336,0.00004269832,3.2240263e-7,0.9885998,0.000027928367,0.00010040763,0.0016015762],"study_design_scores_gemma":[0.00075995526,0.00002594562,0.0037446108,0.000046624515,0.00017077272,0.0001007203,0.000039732477,0.00033683048,0.9898429,0.0000234308,0.0046433606,0.00026510627],"about_ca_topic_score_codex":0.000012343776,"about_ca_topic_score_gemma":0.0000010541384,"teacher_disagreement_score":0.004960755,"about_ca_system_score_codex":0.000025102903,"about_ca_system_score_gemma":0.000056278102,"threshold_uncertainty_score":0.99999857},"labels":[],"label_agreement":null},{"id":"W2921121581","doi":"10.3390/md17030171","title":"Stereo-Selective Pharmacokinetics of Ilimaquinone Epimers Extracted from a Marine Sponge in Rats","year":2019,"lang":"en","type":"article","venue":"Marine Drugs","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Small and Medium Business Administration; National Research Foundation of Korea; Korea Institute for Industrial Economics and Trade; Ministry of Science, ICT and Future Planning; National Research Foundation","keywords":"Sponge; Epimer; Pharmacokinetics; Stereochemistry; Chemistry; Pharmacology; Biology; Computational biology; Botany","score_opus":0.0500949502594407,"score_gpt":0.3741672494659611,"score_spread":0.32407229920652036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921121581","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9571122,0.00011198589,0.000006384905,0.00025734538,0.0010703352,0.00060616556,0.00013225431,0.000051219366,0.040652122],"genre_scores_gemma":[0.9953129,0.00026116095,0.00027572463,0.000634672,0.00015391497,0.000025778523,0.00021982436,0.000040276784,0.003075718],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9978119,0.00038113937,0.00055633415,0.0005035586,0.0002237985,0.00052326947],"domain_scores_gemma":[0.9987563,0.00040968205,0.00026269665,0.00028303135,0.00012208517,0.0001662254],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004149172,0.0003349299,0.00056301366,0.00024263779,0.00005325126,0.000015068875,0.0003695091,0.00023811606,0.010927866],"category_scores_gemma":[0.00003140707,0.0003371585,0.00013626054,0.0004906143,0.00016395778,0.00014751413,0.00047576756,0.00086199713,0.00023340015],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002255843,0.0012829832,0.71045876,0.00008788819,0.00036509102,0.0001234918,0.0009527002,0.00006162169,0.23384093,0.00013563197,0.0010807113,0.049354367],"study_design_scores_gemma":[0.008429076,0.00032411033,0.7153063,0.000041849817,0.00022462723,0.000012935551,0.00034165976,0.0044725495,0.22538874,0.0005914626,0.04420909,0.00065759843],"about_ca_topic_score_codex":0.0008509134,"about_ca_topic_score_gemma":0.00013881744,"teacher_disagreement_score":0.048696768,"about_ca_system_score_codex":0.000109483,"about_ca_system_score_gemma":0.00007297156,"threshold_uncertainty_score":0.99990803},"labels":[],"label_agreement":null},{"id":"W2921268404","doi":"10.1039/c8ob03109f","title":"Synthesis, bioactivity, and enzymatic modification of antibacterial thiotetromycin derivatives","year":2019,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; University of California, San Diego; National Institutes of Health; Eli Lilly and Company","keywords":"Chemistry; Enzyme; Combinatorial chemistry; Surface modification; Organic chemistry","score_opus":0.04414559865457823,"score_gpt":0.351180476558488,"score_spread":0.30703487790390976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921268404","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99555665,0.00030472933,0.0020089503,0.0002024492,0.00018971777,0.00017716725,0.000039237304,0.000034862565,0.0014862133],"genre_scores_gemma":[0.9993423,0.00015046248,0.00017245197,0.000072633076,0.000054886452,0.0000061249475,0.000022828182,0.00002276252,0.00015551355],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989805,0.00012182781,0.00023628668,0.0003201892,0.00012274944,0.00021843282],"domain_scores_gemma":[0.99929893,0.000115966446,0.00019073668,0.00024134676,0.000057250585,0.0000957943],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020896408,0.00018925656,0.00027414953,0.00003483065,0.000072964096,0.00002081321,0.00019321646,0.0002351955,0.0016886649],"category_scores_gemma":[0.00008427918,0.00018492634,0.00006603039,0.00016858231,0.00020126623,0.00007909355,0.00011308457,0.00020995419,0.00003899051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006865294,0.00021457109,0.0076516625,0.00030901187,0.0001387912,0.00000675867,0.00009753945,1.1103402e-7,0.99049616,0.000051749692,0.00004630878,0.0009186964],"study_design_scores_gemma":[0.00056209054,0.000029770728,0.0064292066,0.00004125634,0.000078828176,0.000025915744,0.00009627731,0.00017965764,0.9914211,0.00005513988,0.00088890665,0.00019187004],"about_ca_topic_score_codex":0.0000056120657,"about_ca_topic_score_gemma":2.900451e-7,"teacher_disagreement_score":0.003785664,"about_ca_system_score_codex":0.00003421582,"about_ca_system_score_gemma":0.000056754605,"threshold_uncertainty_score":0.99922395},"labels":[],"label_agreement":null},{"id":"W2929504922","doi":"10.1016/j.molstruc.2019.03.082","title":"Trimerization of Vitamin K3: Molecular structure and density functional theoretic investigations","year":2019,"lang":"en","type":"article","venue":"Journal of Molecular Structure","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Science and Engineering Research Board; Board of Research in Nuclear Sciences; Department of Science and Technology, Ministry of Science and Technology, India; Saskatchewan Pulse Growers","keywords":"Chemistry; Sodium ethoxide; Stacking; Non-covalent interactions; Dimer; Density functional theory; Molecule; Crystallography; Reactivity (psychology); Anthraquinone; Crystal structure; Stereochemistry; Computational chemistry; Organic chemistry; Hydrogen bond","score_opus":0.026466912827477398,"score_gpt":0.3272993511718646,"score_spread":0.3008324383443872,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2929504922","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99572325,0.0004931717,0.0023834715,0.00031579242,0.00074788264,0.00016222095,0.000064654705,0.000006000172,0.00010355439],"genre_scores_gemma":[0.9978186,0.000041068368,0.001284595,0.00070501893,0.000076663615,3.841742e-7,0.00002461349,0.000016409487,0.000032678377],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987803,0.000272997,0.00036713923,0.00016370145,0.0002576112,0.00015825286],"domain_scores_gemma":[0.99891067,0.00006384801,0.00045767726,0.00012678548,0.0002980308,0.00014300922],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016661859,0.00017449234,0.00030272696,0.00014836651,0.000073902214,0.000018544672,0.0001480627,0.00024696745,0.0008488207],"category_scores_gemma":[0.00007849165,0.00014546808,0.000117603566,0.0001946279,0.00022640542,0.00010761803,0.000050821178,0.0005872439,0.0000017238508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016214939,0.000034598834,0.026292715,0.000062185725,0.00024024305,0.000046183522,0.00017394045,0.0012030333,0.9659791,0.0049877493,0.0001843846,0.0006337231],"study_design_scores_gemma":[0.0019020777,0.00023238025,0.05512599,0.00003911526,0.00031995238,0.0004083381,0.000107711814,0.00049667625,0.92646486,0.013765493,0.0009435028,0.00019388292],"about_ca_topic_score_codex":0.000001506909,"about_ca_topic_score_gemma":8.3428796e-7,"teacher_disagreement_score":0.039514214,"about_ca_system_score_codex":0.000028633502,"about_ca_system_score_gemma":0.00011351656,"threshold_uncertainty_score":0.9293992},"labels":[],"label_agreement":null},{"id":"W2948652499","doi":"10.1002/cbic.201900313","title":"Negative Cooperativity in NAD(P)H Quinone Oxidoreductase 1 (NQO1)","year":2019,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Queen's University; Association for International Cancer Research; Medical Research Council; Department of Education and Learning, Northern Ireland","keywords":"Dicoumarol; NAD+ kinase; Cooperativity; Chemistry; Allosteric regulation; Oxidoreductase; Cofactor; Cooperative binding; Binding site; Stereochemistry; Biochemistry; Ligand (biochemistry); Enzyme; Receptor","score_opus":0.09678753024887404,"score_gpt":0.42349251783674036,"score_spread":0.3267049875878663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2948652499","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97264016,0.0003053023,0.000007036818,0.00056755496,0.00085194,0.00040811158,0.000046706253,0.000054508426,0.025118696],"genre_scores_gemma":[0.9940512,0.00006265582,0.00012300682,0.0012108658,0.00015143809,0.0000318788,0.000042033626,0.00002233666,0.0043045497],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855375,0.00016873845,0.00025559022,0.00044448758,0.00012519042,0.000452232],"domain_scores_gemma":[0.999264,0.00015465179,0.00008930469,0.00023828755,0.00008131526,0.00017241886],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00034288544,0.00024571427,0.00031949297,0.00008490427,0.00009488758,0.000023490453,0.000254814,0.00026058816,0.003147502],"category_scores_gemma":[0.000066301465,0.00023754031,0.00008575172,0.0003258966,0.00019983019,0.0001457361,0.00012239136,0.00065150607,0.0008679562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032411842,0.00083207723,0.059503466,0.00007009631,0.00009609141,0.00006813665,0.00083347416,0.000025837662,0.9271357,0.0010135149,0.008063099,0.0020344104],"study_design_scores_gemma":[0.002239,0.00008344775,0.012648685,0.00002264813,0.000019699763,0.000014917316,0.00031288387,0.0004491056,0.9670275,0.00017372576,0.01670076,0.000307625],"about_ca_topic_score_codex":0.000043345226,"about_ca_topic_score_gemma":0.000026630723,"teacher_disagreement_score":0.04685478,"about_ca_system_score_codex":0.0001122588,"about_ca_system_score_gemma":0.000095422605,"threshold_uncertainty_score":0.99991},"labels":[],"label_agreement":null},{"id":"W2950266697","doi":"10.1002/chin.200425113","title":"An Efficient Synthesis of Substituted Anthraquinones and Naphthoquinones.","year":2004,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Chemistry; Anthraquinones; Combinatorial chemistry; Organic chemistry; Computational chemistry; Botany","score_opus":0.0700627554000227,"score_gpt":0.3920244513933453,"score_spread":0.3219616959933226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950266697","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97120345,0.0003097147,0.000012273662,0.000105042454,0.00028127283,0.00014049956,0.00004045217,0.0000476283,0.02785969],"genre_scores_gemma":[0.99942815,0.0001569441,0.0001414799,0.00009393163,0.0000635439,0.000015219032,0.0000118117105,0.000010510931,0.0000784087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992215,0.0000028847485,0.0002379362,0.0001845489,0.00010530597,0.0002478485],"domain_scores_gemma":[0.99940914,0.00008164385,0.000110399735,0.00015781364,0.000070767455,0.00017025908],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021525823,0.00015633735,0.00022442768,0.00007287824,0.00013598491,0.000012551805,0.00016857998,0.00016718992,0.00027358232],"category_scores_gemma":[0.000038264054,0.00013822733,0.000055241657,0.00013895927,0.00042375756,0.00010885002,0.00004886497,0.0001696011,0.000016947995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008625373,0.0024759562,0.015801642,0.0006025579,0.0004136853,0.0001218549,0.003289866,0.00050411955,0.70388365,0.011301155,0.0006517205,0.26009125],"study_design_scores_gemma":[0.0009372116,0.000050304883,0.009400133,0.00003532021,0.00007051799,0.000042252334,0.00027205565,0.00019436078,0.985592,0.000083475454,0.003129507,0.00019287685],"about_ca_topic_score_codex":0.000021983462,"about_ca_topic_score_gemma":0.0000041329604,"teacher_disagreement_score":0.28170833,"about_ca_system_score_codex":0.00003563621,"about_ca_system_score_gemma":0.000051456936,"threshold_uncertainty_score":0.5636747},"labels":[],"label_agreement":null},{"id":"W2950291420","doi":"10.1002/chin.200219054","title":"ChemInform Abstract: Excited State Intramolecular Redox Reaction of 2‐(Hydroxymethyl)anthraquinone in Aqueous Solution.","year":2002,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Chemistry; Intramolecular force; Hydroxymethyl; Redox; Anthraquinone; Aqueous solution; Excited state; Photochemistry; Combinatorial chemistry; Stereochemistry; Organic chemistry; Atomic physics","score_opus":0.07538262619201638,"score_gpt":0.35866601442971235,"score_spread":0.28328338823769594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950291420","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.43288192,0.00096507336,0.0000027071007,0.00022483189,0.00050739426,0.00036056255,0.00005200696,0.000085686814,0.5649198],"genre_scores_gemma":[0.98741245,0.00072843244,0.000027937345,0.0003074074,0.000087565735,0.000030990264,0.00006604578,0.000023278371,0.011315882],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982792,0.0000012020695,0.00068770634,0.00026766807,0.00022735543,0.0005368305],"domain_scores_gemma":[0.9989872,0.00010867373,0.00035000124,0.00025674625,0.00011598742,0.00018140781],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00039176588,0.0002759987,0.00036567307,0.00020739766,0.000105983425,0.000016927528,0.00026912836,0.0003479852,0.002955985],"category_scores_gemma":[0.00008759863,0.00028277922,0.0001350514,0.00041148515,0.00030385648,0.000326141,0.000085999614,0.00071311713,0.00013558991],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021134922,0.000589142,0.0003221615,0.00018172567,0.00012106896,0.00008921991,0.0010677045,0.000005019248,0.31775478,0.00005908088,0.01692207,0.6626767],"study_design_scores_gemma":[0.0016908266,0.00008427908,0.0025423027,0.0000529439,0.000041248753,0.000050029197,0.00011412397,0.0010374108,0.867069,0.00011564481,0.12687355,0.00032862113],"about_ca_topic_score_codex":0.00007488267,"about_ca_topic_score_gemma":0.000015776892,"teacher_disagreement_score":0.6623481,"about_ca_system_score_codex":0.00019309399,"about_ca_system_score_gemma":0.000035831596,"threshold_uncertainty_score":0.99996245},"labels":[],"label_agreement":null},{"id":"W2950394256","doi":"10.1002/chin.200610219","title":"Novel and Expanded Jadomycins Incorporating Non‐proteogenic Amino Acids.","year":2006,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Chemistry; Combinatorial chemistry","score_opus":0.07155703273549265,"score_gpt":0.363185647980783,"score_spread":0.2916286152452904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950394256","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.76846004,0.0001958168,0.00007122363,0.00017758046,0.00034914896,0.0003102851,0.00003921175,0.000079808,0.23031689],"genre_scores_gemma":[0.99243885,0.000028175418,0.00043875838,0.0005846729,0.0003197909,0.00003715576,0.00005780046,0.000017567905,0.0060772155],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990046,0.0000017959915,0.00029641378,0.00024103264,0.000109586086,0.00034655578],"domain_scores_gemma":[0.9994424,0.000060471477,0.0001613463,0.00013829359,0.00006292518,0.00013453863],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020879951,0.00021767127,0.0002164243,0.00006158034,0.00026639554,0.00003991595,0.00016226587,0.00022938244,0.0002518125],"category_scores_gemma":[0.000018753382,0.0002014735,0.00007045005,0.00014291136,0.00021713524,0.0001875345,0.00012988962,0.00036815228,0.000053009004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014657645,0.0003421301,0.03721289,0.00012268494,0.00010357329,0.000029030234,0.00032850282,0.0000036828308,0.8676174,0.0011753483,0.01157546,0.081342705],"study_design_scores_gemma":[0.0028557908,0.00007527723,0.029666753,0.000023760967,0.00007407386,0.00010822582,0.00018280427,0.0006649525,0.9040694,0.0003419405,0.061513864,0.00042310994],"about_ca_topic_score_codex":0.000045684585,"about_ca_topic_score_gemma":0.00001913324,"teacher_disagreement_score":0.22423968,"about_ca_system_score_codex":0.00005389097,"about_ca_system_score_gemma":0.000048791215,"threshold_uncertainty_score":0.82158506},"labels":[],"label_agreement":null},{"id":"W2950534807","doi":"10.1002/chin.200925191","title":"ChemInform Abstract: Total Synthesis of FR901483 (V).","year":2009,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Service (business); Combinatorial chemistry; Business; Marketing","score_opus":0.07098265046401872,"score_gpt":0.3789144704614589,"score_spread":0.3079318199974401,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950534807","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.1502679,0.00013478001,1.684374e-7,0.0002809585,0.000293027,0.00013423031,0.000048109305,0.00006102213,0.8487798],"genre_scores_gemma":[0.9859404,0.00010099806,0.000027096346,0.0006167591,0.00016967133,0.000011453129,0.000022331407,0.000010207417,0.013101097],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988472,1.9757718e-7,0.000418401,0.00017648032,0.00017133824,0.00038639666],"domain_scores_gemma":[0.99913937,0.0001507924,0.00021987641,0.00020920567,0.0000943911,0.0001863454],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00024859002,0.00021796825,0.00030633097,0.0000728054,0.00010751149,0.000014939175,0.00027864423,0.00028292942,0.005237695],"category_scores_gemma":[0.00009559097,0.00019943558,0.00017227551,0.0001548129,0.00016029633,0.00021304747,0.000050156694,0.00036198375,0.0001435359],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016236231,0.00029267496,0.00033826203,0.00007833375,0.0000888499,0.000013867233,0.0003189034,5.890022e-7,0.037409205,0.00069270434,0.043771412,0.91683286],"study_design_scores_gemma":[0.0005013984,0.00006102341,0.014787931,0.000028275535,0.000060677274,0.000028244529,0.00014455925,0.00002240629,0.882153,0.00012925387,0.101849064,0.00023415897],"about_ca_topic_score_codex":0.000005598575,"about_ca_topic_score_gemma":6.710049e-7,"teacher_disagreement_score":0.9165987,"about_ca_system_score_codex":0.000058864065,"about_ca_system_score_gemma":0.000062601124,"threshold_uncertainty_score":0.99567163},"labels":[],"label_agreement":null},{"id":"W2950558484","doi":"10.1002/chin.200421208","title":"Three‐Component Homo [3 + 2] Dipolar Cycloaddition. A Diversity‐Oriented Synthesis of Tetrahydro‐1,2‐oxazines and FR900482 Skeletal Congeners.","year":2004,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Oxazines; Component (thermodynamics); Cycloaddition; Dipole; Stereochemistry; Diversity (politics); 1,3-Dipolar cycloaddition; Combinatorial chemistry; Organic chemistry; Catalysis","score_opus":0.05044649804593998,"score_gpt":0.3271054504278863,"score_spread":0.2766589523819463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950558484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9626315,0.000850254,0.000048255504,0.00036389168,0.0004952637,0.00027359853,0.00036647316,0.000076360026,0.034894396],"genre_scores_gemma":[0.998817,0.00038538186,0.00015115354,0.00023956255,0.00012087687,0.000019393208,0.00006273176,0.00001355321,0.00019029167],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989357,0.0000034616523,0.00028781214,0.0002556502,0.00018721946,0.00033015112],"domain_scores_gemma":[0.9992187,0.00013672592,0.00016656287,0.00017292435,0.00010009124,0.00020502145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001760321,0.00023331183,0.0003128542,0.000103187274,0.0003760235,0.000013440352,0.0002667957,0.00021662565,0.0005654476],"category_scores_gemma":[0.00006067503,0.00021860834,0.00013243727,0.00017592868,0.00051072566,0.00018715362,0.00038998036,0.00029025425,0.000032606382],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016518955,0.005105056,0.1366414,0.0017249306,0.004626945,0.0004568366,0.007136563,0.0000828768,0.28960857,0.021291507,0.032856546,0.49881688],"study_design_scores_gemma":[0.003555492,0.00018056715,0.039915342,0.00012216071,0.00049245957,0.000075648735,0.00044147347,0.00015042319,0.88318044,0.0013053545,0.06994902,0.0006316187],"about_ca_topic_score_codex":0.00007698946,"about_ca_topic_score_gemma":0.000029902329,"teacher_disagreement_score":0.59357184,"about_ca_system_score_codex":0.00008254618,"about_ca_system_score_gemma":0.00004350783,"threshold_uncertainty_score":0.891459},"labels":[],"label_agreement":null},{"id":"W2951187224","doi":"10.1002/chin.200127212","title":"ChemInform Abstract: A Synthesis of Puraquinonic Acid.","year":2001,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Service (business); Computer science; Information retrieval; World Wide Web; Business; Marketing","score_opus":0.09131924981426776,"score_gpt":0.38401137224402715,"score_spread":0.2926921224297594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951187224","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.17525688,0.00026576506,2.3483193e-7,0.00018741071,0.0003208785,0.00015335975,0.000036222817,0.0000618877,0.82371736],"genre_scores_gemma":[0.9802696,0.00052297127,0.00001838512,0.0003863289,0.00015691183,0.00004169933,0.00002198243,0.000017562214,0.018564537],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987319,2.596341e-7,0.00044558762,0.0001921668,0.00017939291,0.0004506534],"domain_scores_gemma":[0.99902177,0.00017412085,0.000248555,0.00024751047,0.00010769473,0.00020037768],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003005638,0.00023138116,0.0003200828,0.00008664553,0.000121143334,0.00001623534,0.00038046177,0.0002983549,0.010979196],"category_scores_gemma":[0.000106180414,0.00021035875,0.00018213787,0.00022858218,0.00024923368,0.00023762463,0.00010417922,0.00038175934,0.0002725357],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000269203,0.0002861262,0.0025681364,0.00016431573,0.00019086884,0.000041692143,0.00034972417,2.6996094e-7,0.05067882,0.00035725327,0.033544865,0.91154873],"study_design_scores_gemma":[0.00046155232,0.000027449832,0.003868367,0.000026336382,0.00006048156,0.000051956107,0.00017122351,0.000014275036,0.6811805,0.000049958242,0.31390065,0.00018729286],"about_ca_topic_score_codex":0.000011296364,"about_ca_topic_score_gemma":0.0000041218427,"teacher_disagreement_score":0.91136146,"about_ca_system_score_codex":0.00008068468,"about_ca_system_score_gemma":0.000080889666,"threshold_uncertainty_score":0.9899249},"labels":[],"label_agreement":null},{"id":"W2951239749","doi":"10.1021/ol016562k","title":"The Diels−Alder Reactions of Quinone Imine Ketals:  A Versatile Synthesis of Highly Substituted 5-Methoxyindoles","year":2001,"lang":"en","type":"article","venue":"Organic Letters","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Imine; Quinone; Yield (engineering); Organic chemistry; Diels–Alder reaction; Combinatorial chemistry; Catalysis","score_opus":0.07855024250679302,"score_gpt":0.3689226271181528,"score_spread":0.29037238461135984,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951239749","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915107,0.00031766572,0.00027355496,0.006182995,0.0006666901,0.00018020446,0.000039427203,0.000036081772,0.0007927108],"genre_scores_gemma":[0.99816096,0.0007241131,0.00013705094,0.0006325289,0.000120626246,0.00001544035,0.0000065605705,0.000020467623,0.00018228084],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99865824,0.00030368962,0.00038764963,0.00020127495,0.00015524928,0.00029387392],"domain_scores_gemma":[0.99831736,0.0009832137,0.00027411347,0.0002610119,0.000084078056,0.00008023454],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046517912,0.00016566223,0.0002753354,0.000081334714,0.00026032352,0.00001132279,0.00030353776,0.00012060111,0.000793454],"category_scores_gemma":[0.00019632063,0.0001252069,0.00012606713,0.00033144784,0.00047963753,0.000094508316,0.000065666034,0.000300731,0.000037045003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002052004,0.00023054396,0.007363219,0.000034125438,0.00034634088,0.00002222916,0.00019652276,0.00001477282,0.98440945,0.00028513657,0.0040074983,0.0028849845],"study_design_scores_gemma":[0.0008140659,0.000040349103,0.016124884,0.000037336315,0.00027325418,0.000033176006,0.00027577823,0.00011145683,0.9318316,0.000038317732,0.05024294,0.00017684423],"about_ca_topic_score_codex":0.00006642808,"about_ca_topic_score_gemma":0.000037180464,"teacher_disagreement_score":0.05257783,"about_ca_system_score_codex":0.000049870727,"about_ca_system_score_gemma":0.000044505727,"threshold_uncertainty_score":0.8687765},"labels":[],"label_agreement":null},{"id":"W2951700673","doi":"10.1002/chin.200810224","title":"ChemInform Abstract: Total Synthesis of Streptonigrone.","year":2008,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Service (business); Total synthesis; Combinatorial chemistry; Nanotechnology; Stereochemistry; Business; Marketing","score_opus":0.09673656448490599,"score_gpt":0.3673750246612622,"score_spread":0.27063846017635623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951700673","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.39606333,0.00010374316,9.008504e-8,0.00005996772,0.00024630298,0.0001001379,0.000052138468,0.00004362858,0.6033307],"genre_scores_gemma":[0.9759247,0.00025561292,0.000024465866,0.0001728283,0.00013938107,0.000026258844,0.000025168069,0.000015637752,0.023415947],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99882793,2.1720862e-7,0.00042436318,0.00018194185,0.00018854826,0.0003769986],"domain_scores_gemma":[0.9990705,0.00019142314,0.00022357435,0.00021835123,0.00010229741,0.00019379942],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018203924,0.00021480229,0.000309377,0.00007705473,0.00017873247,0.000006793099,0.00025959124,0.0002674928,0.007979644],"category_scores_gemma":[0.000089994595,0.00019974115,0.00017470361,0.0001605262,0.00038307157,0.00021055649,0.00009275652,0.0003556131,0.000178261],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004014286,0.0007976152,0.009851824,0.00041353368,0.00045086915,0.00009295546,0.001817603,0.0000023849348,0.06552188,0.00053853984,0.14987174,0.77023965],"study_design_scores_gemma":[0.00051816076,0.000033140466,0.021448158,0.000022885875,0.000040356874,0.00008410682,0.00020528334,0.000019648965,0.89863235,0.000015655456,0.07875007,0.0002301641],"about_ca_topic_score_codex":0.000016759002,"about_ca_topic_score_gemma":0.0000014134563,"teacher_disagreement_score":0.8331105,"about_ca_system_score_codex":0.00006430432,"about_ca_system_score_gemma":0.00010863001,"threshold_uncertainty_score":0.9929272},"labels":[],"label_agreement":null},{"id":"W2951882971","doi":"10.1002/chin.200125195","title":"ChemInform Abstract: Synthesis of (.+‐.)‐Puraquinonic Acid: An Inducer of Cell Differentiation.","year":2001,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Inducer; Service (business); Combinatorial chemistry; World Wide Web; Stereochemistry; Biochemistry; Business; Marketing; Computer science","score_opus":0.0862829549278538,"score_gpt":0.36938700253870094,"score_spread":0.2831040476108471,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951882971","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6032284,0.00010237104,3.8153868e-7,0.000029007082,0.00018923149,0.000119303615,0.00004634752,0.000024282534,0.39626068],"genre_scores_gemma":[0.99463916,0.00030513937,0.000026062082,0.00011881616,0.000102944825,0.000023104836,0.000056982717,0.000017870036,0.0047099157],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987314,6.655496e-7,0.0005470553,0.00018572349,0.00019695847,0.00033820176],"domain_scores_gemma":[0.998827,0.00013355634,0.0004360057,0.00027246858,0.000154985,0.00017597839],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00024147278,0.00022269467,0.00035309166,0.000106699525,0.00008809257,0.000011275087,0.00037264382,0.00032189648,0.0066594332],"category_scores_gemma":[0.000043537522,0.00020325926,0.0001511062,0.00019704385,0.00020427028,0.00031657304,0.00008411464,0.00033237052,0.000045992812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030122584,0.00096688455,0.007057595,0.00036177438,0.00016901857,0.000008781215,0.0009364957,7.216113e-7,0.61261535,0.00017567736,0.00392481,0.37348166],"study_design_scores_gemma":[0.0006653096,0.000062561485,0.021531582,0.000025491388,0.000105310886,0.0000101562455,0.0003443385,0.000029786563,0.9581696,0.00004337376,0.018807216,0.00020531903],"about_ca_topic_score_codex":0.000016923123,"about_ca_topic_score_gemma":0.0000049668265,"teacher_disagreement_score":0.39155075,"about_ca_system_score_codex":0.000057778154,"about_ca_system_score_gemma":0.000081294274,"threshold_uncertainty_score":0.9942486},"labels":[],"label_agreement":null},{"id":"W2952132909","doi":"10.1002/chin.200622087","title":"Synthesis of Aryl‐Substituted 1,4‐Benzoquinone via Water‐Promoted and In(OTf)<sub>3</sub>‐Catalyzed in situ Conjugate Addition‐Dehydration of Aromatic Compounds to 1,4‐Benzoquinone in Water.","year":2006,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Chemistry; Benzoquinone; Conjugate; Dehydration; In situ; Aryl; Catalysis; 1,4-Benzoquinone; Combinatorial chemistry; Organic chemistry; Quinone; Biochemistry; Alkyl","score_opus":0.02949176313527126,"score_gpt":0.30415555276909223,"score_spread":0.274663789633821,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952132909","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951348,0.00006416238,0.000011222353,0.00016615455,0.00014451714,0.0006054834,0.00007780289,0.000027600245,0.0037682713],"genre_scores_gemma":[0.99912363,0.000053766882,0.000048705086,0.000075864686,0.00003981356,0.000093460985,0.0005121429,0.000020962358,0.000031651685],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979058,0.0000153902,0.0010429389,0.00032745724,0.00019038646,0.000518051],"domain_scores_gemma":[0.9992028,0.00020084807,0.00019547272,0.0002091508,0.00007541121,0.00011635406],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00060235977,0.00030728613,0.0006642676,0.000503975,0.0000646242,0.000017164148,0.00021966832,0.00030218062,0.00010210304],"category_scores_gemma":[0.000048099584,0.0002604929,0.00007237076,0.0003967973,0.00026610016,0.00031872978,0.00012666141,0.000326984,0.000032374788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005336196,0.00066348986,0.0038752845,0.00030798803,0.00004776549,0.00004247564,0.00089413824,0.00008783196,0.9895315,0.000022588687,0.00017308877,0.003820184],"study_design_scores_gemma":[0.002045535,0.000058481775,0.02890123,0.0002338126,0.00005021167,0.000018052355,0.00009854722,0.000628342,0.9671662,0.0003881688,0.0001083891,0.0003030165],"about_ca_topic_score_codex":0.00021466504,"about_ca_topic_score_gemma":0.0009222537,"teacher_disagreement_score":0.025025945,"about_ca_system_score_codex":0.00014726198,"about_ca_system_score_gemma":0.000037326092,"threshold_uncertainty_score":0.99998474},"labels":[],"label_agreement":null},{"id":"W2952366091","doi":"10.1002/chin.200312193","title":"Caminoside A (I), an Antimicrobial Glycolipid Isolated from the Marine Sponge Caminus sphaeroconia","year":2003,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Sponge; Antimicrobial; Glycolipid; Stereochemistry; Microbiology; Organic chemistry; Biochemistry; Botany","score_opus":0.07036573433868566,"score_gpt":0.359373598548162,"score_spread":0.28900786420947633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952366091","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8790287,0.00012318572,0.0000071998493,0.0002368574,0.0013019822,0.00037840285,0.00015042824,0.000096865944,0.1186764],"genre_scores_gemma":[0.98937476,0.00010812445,0.00008975709,0.003973969,0.00039894637,0.000026195743,0.00019918135,0.00002964588,0.005799415],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99861467,0.000018812321,0.00035481917,0.00033193498,0.00012675597,0.0005529797],"domain_scores_gemma":[0.99896705,0.00017947241,0.00015925881,0.00035833928,0.00009081859,0.00024506781],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00030603673,0.0003103128,0.00027767182,0.000036493304,0.00040190603,0.00006455685,0.00045244966,0.00031276097,0.005082211],"category_scores_gemma":[0.000065777334,0.00023801386,0.000118339914,0.00020216046,0.00026965063,0.00023135923,0.00013313879,0.0006414037,0.00027536118],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002448501,0.0018441209,0.13376841,0.0001197834,0.0012880232,0.00055112364,0.005339415,0.000010449087,0.3122116,0.0022742348,0.17463471,0.36550963],"study_design_scores_gemma":[0.0022651313,0.00009918726,0.017812155,0.000013102696,0.00015063267,0.00011784692,0.00022751713,0.00020280147,0.3833919,0.00011275614,0.59517944,0.00042756755],"about_ca_topic_score_codex":0.00020330888,"about_ca_topic_score_gemma":0.000165829,"teacher_disagreement_score":0.42054468,"about_ca_system_score_codex":0.000091141716,"about_ca_system_score_gemma":0.000108298445,"threshold_uncertainty_score":0.99582726},"labels":[],"label_agreement":null},{"id":"W2952516740","doi":"10.1002/chin.200027218","title":"ChemInform Abstract: Synthesis of a Novel Thyrotropin Releasing Hormone (TRH) Analogue Incorporating a Piperazin‐2‐one Ring.","year":2000,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Chemistry; Thyrotropin-releasing hormone; Ring (chemistry); Combinatorial chemistry; Stereochemistry; Hormone; Organic chemistry; Biochemistry","score_opus":0.09355866580076751,"score_gpt":0.35773043813194766,"score_spread":0.26417177233118017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952516740","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3969993,0.00032967198,0.0000020615705,0.000202896,0.00011611037,0.00026365113,0.00010836621,0.00009224732,0.60188574],"genre_scores_gemma":[0.9932836,0.00055149244,0.00037090798,0.00053910294,0.00023693655,0.000053105166,0.0000669295,0.000035548775,0.0048623467],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980799,7.8833426e-7,0.0007702767,0.00031937571,0.0002771764,0.0005524594],"domain_scores_gemma":[0.9986443,0.00024003389,0.00041750804,0.00030918472,0.00013936475,0.00024962059],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00032300738,0.00035367245,0.00052016985,0.0001252374,0.00027108623,0.000038275553,0.00040954284,0.00039005556,0.0030737475],"category_scores_gemma":[0.0001314321,0.00035019976,0.00020497803,0.00035342213,0.0003542286,0.0003717115,0.00010134655,0.00067787553,0.00011053512],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005227609,0.0008129897,0.00035017967,0.000261012,0.0002869933,0.000018710703,0.0006440823,0.000010491107,0.21022242,0.00038850043,0.006407587,0.7800743],"study_design_scores_gemma":[0.0027700595,0.00013216662,0.014019626,0.00023353555,0.00021783893,0.00007216661,0.00036764215,0.0008378127,0.9081368,0.000083283034,0.072393686,0.0007353806],"about_ca_topic_score_codex":0.000073968244,"about_ca_topic_score_gemma":0.000007640028,"teacher_disagreement_score":0.7793389,"about_ca_system_score_codex":0.00013591412,"about_ca_system_score_gemma":0.00011481305,"threshold_uncertainty_score":0.999895},"labels":[],"label_agreement":null},{"id":"W2952938380","doi":"10.1002/chin.200418196","title":"The Difluoromethylene Group as a Replacement for the Labile Oxygen in Steroid Sulfates: a New Approach to Steroid Sulfatase Inhibitors.","year":2004,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Chemistry; Steroid sulfatase; Steroid; Stereochemistry; Humanities; Art; Biochemistry","score_opus":0.08843018977826005,"score_gpt":0.3849828258683846,"score_spread":0.29655263609012456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952938380","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8872354,0.004625258,0.00061862124,0.0146177905,0.0032144722,0.008827847,0.00045573775,0.00021963625,0.08018524],"genre_scores_gemma":[0.9819109,0.00041209723,0.00041099967,0.004760629,0.0005475858,0.0009241689,0.00015148293,0.00004498428,0.010837192],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982741,0.000010161707,0.00047969763,0.00038491946,0.00021002546,0.0006410932],"domain_scores_gemma":[0.9986445,0.00043616685,0.00014721189,0.00043462627,0.0000644678,0.00027307274],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011012686,0.00028915843,0.00025502162,0.000070387505,0.00048970303,0.000105282736,0.00064182753,0.00018467955,0.00012398801],"category_scores_gemma":[0.00015409166,0.000179604,0.00013819165,0.00033344812,0.0001638768,0.00015150536,0.00026140016,0.0004538144,0.00012076816],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008843157,0.0029922999,0.0021301687,0.0004353628,0.0010850737,0.000029677249,0.018469768,0.0003238463,0.081081584,0.0076033226,0.36984032,0.50716543],"study_design_scores_gemma":[0.0048456416,0.000329688,0.0009396108,0.000030888976,0.00007276171,0.000019102077,0.0017672204,0.00007193698,0.18868013,0.00057145074,0.8023506,0.00032099683],"about_ca_topic_score_codex":0.00013526707,"about_ca_topic_score_gemma":0.00009790852,"teacher_disagreement_score":0.5068444,"about_ca_system_score_codex":0.0002814109,"about_ca_system_score_gemma":0.0001407363,"threshold_uncertainty_score":0.7324039},"labels":[],"label_agreement":null},{"id":"W2953304876","doi":"10.1002/chin.200708228","title":"Aminoglycosides: Ancient and Modern","year":2007,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; World Wide Web; Nanotechnology; Computer science","score_opus":0.10719295434253542,"score_gpt":0.41221948977718487,"score_spread":0.3050265354346494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953304876","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.65245247,0.00057465467,0.000060316757,0.00009121743,0.000376058,0.00010932515,0.000009293615,0.00005359769,0.34627303],"genre_scores_gemma":[0.9925237,0.00010364383,0.00008296123,0.0019041339,0.0001330211,0.000004600331,0.000010053282,0.000008745686,0.0052290973],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992315,7.9784434e-7,0.00017673722,0.00015782818,0.0000877336,0.00034537292],"domain_scores_gemma":[0.99951375,0.000082182356,0.000057331425,0.00009734293,0.00004252714,0.00020684174],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003848922,0.00012442155,0.00011712404,0.000049424387,0.0001459546,0.000016294287,0.00010723886,0.00014402461,0.00032976997],"category_scores_gemma":[0.000022799317,0.00011157336,0.000039467996,0.000084893574,0.00016831457,0.000100266436,0.000077159515,0.00024217917,0.00005392271],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017400541,0.00015164303,0.015421061,0.0000618185,0.00006814474,0.000055537646,0.0013152322,6.5411956e-7,0.06956184,0.0011032919,0.020886717,0.89120007],"study_design_scores_gemma":[0.0009212434,0.000051311625,0.025533883,0.000010127403,0.00003350787,0.000060095765,0.00025879501,0.0003637308,0.48290786,0.00030423948,0.489323,0.00023221674],"about_ca_topic_score_codex":0.000003759873,"about_ca_topic_score_gemma":0.000006334401,"teacher_disagreement_score":0.89096785,"about_ca_system_score_codex":0.000045249704,"about_ca_system_score_gemma":0.000019009585,"threshold_uncertainty_score":0.45498297},"labels":[],"label_agreement":null},{"id":"W2981799902","doi":"10.3390/cancers11111646","title":"STAT3: An Emerging Therapeutic Target for Hepatocellular Carcinoma","year":2019,"lang":"en","type":"review","venue":"Cancers","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":135,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Health and Medical Research Fund; Terry Fox Foundation","keywords":"STAT3; Hepatocellular carcinoma; Medicine; STAT protein; Cancer research; Targeted therapy; Clinical trial; Transcription factor; Metastasis; Cancer; Oncology; Internal medicine; Biology; Signal transduction; Gene","score_opus":0.37632641200594713,"score_gpt":0.5037783466143937,"score_spread":0.12745193460844656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2981799902","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00042980447,0.99110204,0.00034072908,0.000024845642,0.0044850614,0.0018855388,0.00078518596,0.000070856724,0.00087595684],"genre_scores_gemma":[0.0028901908,0.99250644,0.00013854339,0.0005639057,0.00076337624,0.00042977213,0.00059437036,0.0001290468,0.0019843578],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976337,0.00039388362,0.0004773747,0.000681755,0.0001320746,0.00068121805],"domain_scores_gemma":[0.99869287,0.00020244703,0.00037440457,0.00038420476,0.00009319462,0.00025288176],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00039931192,0.0005603106,0.0013481115,0.00015360324,0.00027066382,0.00003813005,0.0005648614,0.0005666934,0.00100747],"category_scores_gemma":[0.000009835477,0.00049240806,0.0006005183,0.00020275083,0.00014597012,0.00011137164,0.00006539428,0.0007776811,0.00012011207],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008855836,0.00006234677,0.00058618607,0.013926894,0.0009235599,0.000036222522,0.0001837293,0.00005226485,0.000040778854,0.00057721173,0.0063469913,0.97717524],"study_design_scores_gemma":[0.0006051143,0.00021210175,0.0000037211234,0.00045993336,0.0014517119,0.000010717414,0.000052284864,0.0026529718,0.00005681955,0.00008846492,0.99382555,0.00058061606],"about_ca_topic_score_codex":0.000035093562,"about_ca_topic_score_gemma":0.000004520875,"teacher_disagreement_score":0.98747855,"about_ca_system_score_codex":0.0010444599,"about_ca_system_score_gemma":0.0013987144,"threshold_uncertainty_score":0.99990577},"labels":[],"label_agreement":null},{"id":"W2994119889","doi":"10.1002/chem.201904607","title":"An Activatable Photosensitizer Targeting Human NAD(P)H: Quinone Oxidoreductase 1","year":2019,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"NAD+ kinase; Photosensitizer; Quinone; Oxidoreductase; Chemistry; Stereochemistry; Photochemistry; Biochemistry; Enzyme","score_opus":0.07695641304058672,"score_gpt":0.3950037925198306,"score_spread":0.3180473794792439,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2994119889","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9742604,0.0001671797,0.000028225091,0.00012771139,0.00076147565,0.00011231259,0.000036939695,0.000080166355,0.024425585],"genre_scores_gemma":[0.9933922,0.000030789375,0.00035990876,0.0006572214,0.0014746669,0.0000014149987,0.000073873,0.00006805534,0.003941853],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977517,0.0006070694,0.00042948054,0.0004015497,0.00020617292,0.0006040275],"domain_scores_gemma":[0.9986424,0.000044494078,0.0003111877,0.0002878295,0.00014652852,0.0005675907],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0012320994,0.0003029436,0.00027895885,0.000044226086,0.0006599862,0.0001445727,0.000499984,0.00010419377,0.010270772],"category_scores_gemma":[0.000035775123,0.00028692008,0.00015076157,0.00012770902,0.0001619524,0.0002172425,0.00011378269,0.001572196,0.00048928225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014219464,0.00034876712,0.0035691333,0.000048368256,0.00011552557,0.0007606201,0.00024061167,0.00008717388,0.98180765,0.0000062860363,0.012045811,0.00082786055],"study_design_scores_gemma":[0.0029224253,0.00016074214,0.002307749,0.00006220033,0.00009014926,0.0013037729,0.0008949488,0.0012244427,0.8328965,0.00003566548,0.15750544,0.0005959998],"about_ca_topic_score_codex":0.0000027540164,"about_ca_topic_score_gemma":1.0958992e-7,"teacher_disagreement_score":0.14891118,"about_ca_system_score_codex":0.00008895917,"about_ca_system_score_gemma":0.00007144881,"threshold_uncertainty_score":0.9999583},"labels":[],"label_agreement":null},{"id":"W2995594743","doi":"10.1038/s41598-019-55839-8","title":"Biological Evaluation of Noscapine analogues as Potent and Microtubule-Targeted Anticancer Agents","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"University of Delhi; Council of Scientific and Industrial Research, India; Indian Council of Medical Research","keywords":"Noscapine; Microtubule; Computational biology; Pharmacology; Bioinformatics; Chemistry; Biology; Genetics; Alkaloid; Stereochemistry","score_opus":0.17621271477930298,"score_gpt":0.44370715562167234,"score_spread":0.2674944408423694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2995594743","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98865235,0.0012011,0.000007818115,0.00014528455,0.0064577116,0.00060106715,0.000014480696,0.00002556588,0.0028946355],"genre_scores_gemma":[0.9985739,0.00010467004,0.00008038768,0.0001679272,0.000048563852,0.00001411769,0.00010227135,0.000008024267,0.0009001557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979334,0.0003059249,0.00043063727,0.0006137922,0.00043198408,0.00028424646],"domain_scores_gemma":[0.9987859,0.000048058144,0.000320309,0.00031015414,0.00040115457,0.00013439052],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0029691176,0.00015225996,0.00025717332,0.00013679262,0.0001813386,0.000043066713,0.00011446817,0.00015379692,0.0028031536],"category_scores_gemma":[0.00013750463,0.00012166386,0.000084763386,0.00027413585,0.00047461383,0.000099157034,0.0001102584,0.00017912684,0.00008413852],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006920916,0.00029342558,0.3234028,0.000036269063,0.00011870227,0.00005919234,0.00020855122,0.0000662565,0.663526,0.00009376354,0.0051744604,0.0069513684],"study_design_scores_gemma":[0.0018447414,0.0003072768,0.41931048,0.000071965296,0.00031132647,0.0002918903,0.00026837966,0.005526469,0.47569624,0.0058292183,0.09006792,0.00047408673],"about_ca_topic_score_codex":0.000021970633,"about_ca_topic_score_gemma":0.000004748485,"teacher_disagreement_score":0.18782975,"about_ca_system_score_codex":0.000045014236,"about_ca_system_score_gemma":0.00012580746,"threshold_uncertainty_score":0.99810845},"labels":[],"label_agreement":null},{"id":"W3031246863","doi":"10.1038/s41438-020-0301-9","title":"Hybrid de novo genome assembly of red gromwell (Lithospermum erythrorhizon) reveals evolutionary insight into shikonin biosynthesis","year":2020,"lang":"en","type":"article","venue":"Horticulture Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McGill University; Purdue University; U.S. Department of Agriculture; National Institute of Food and Agriculture; National Science Foundation","keywords":"Biology; Genome; Sequence assembly; Gene; Proteome; Transcriptome; Botany; Whole genome sequencing; Genetics; Gene expression","score_opus":0.18347389646925097,"score_gpt":0.44390897836151616,"score_spread":0.26043508189226516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3031246863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97810197,0.0031453043,0.00011509077,0.010348237,0.00018509327,0.00061811146,0.00012589863,0.00008449913,0.0072758063],"genre_scores_gemma":[0.99575794,0.0012362066,0.00084371126,0.0008768572,0.00051116315,0.000053309028,0.00006166575,0.000037804428,0.00062135165],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9959265,0.0014343383,0.0005319678,0.0006061981,0.00062209397,0.00087892025],"domain_scores_gemma":[0.9978995,0.00045632507,0.00014318753,0.00028839792,0.0005890445,0.0006235987],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001325582,0.00028114932,0.00047120437,0.00016167837,0.0004863216,0.00004228444,0.00064284663,0.00034250898,0.0013558279],"category_scores_gemma":[0.0005839298,0.00023355943,0.00020221071,0.0007313548,0.00059584086,0.00018670164,0.00035102307,0.0013725943,0.0002534473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00057973777,0.000551645,0.01307477,0.00025186624,0.00030416143,0.0003332557,0.0018383316,0.000028472983,0.9624052,0.0009433881,0.018552436,0.0011367393],"study_design_scores_gemma":[0.0015596198,0.00082532526,0.09910344,0.00011616663,0.00018547232,0.00011948186,0.00075134914,0.0013682303,0.58978236,0.00080375763,0.30473602,0.00064879],"about_ca_topic_score_codex":0.00004184086,"about_ca_topic_score_gemma":0.000009437128,"teacher_disagreement_score":0.37262288,"about_ca_system_score_codex":0.00025127325,"about_ca_system_score_gemma":0.0002481202,"threshold_uncertainty_score":0.9995571},"labels":[],"label_agreement":null},{"id":"W3044179993","doi":"10.1039/d0ob01368d","title":"Discovery and properties of a new indigoid structure type based on dimeric <i>cis</i>-indigos","year":2020,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; University of Victoria","keywords":"Indigo; Chemistry; Indole test; Sodium hydride; Hydride; Stereochemistry; Redox; Crystallography; Photochemistry; Medicinal chemistry; Organic chemistry; Metal","score_opus":0.05923818239282216,"score_gpt":0.3229394996309035,"score_spread":0.2637013172380814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3044179993","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99524784,0.0011137212,0.0016575825,0.0011073018,0.00018168379,0.0001750485,0.00005097317,0.00004583542,0.0004200213],"genre_scores_gemma":[0.99684566,0.000058885453,0.00006996448,0.002589833,0.0001309479,0.0000015021396,0.00003360696,0.00002991645,0.00023966069],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902904,0.0000529178,0.00019194606,0.00034097923,0.00015253933,0.00023254973],"domain_scores_gemma":[0.99944955,0.00001752986,0.00011721485,0.00016435883,0.00004187435,0.0002094627],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004568268,0.00022462317,0.00024127713,0.000019819618,0.00008657979,0.00002907475,0.00021428223,0.00021741762,0.0006061171],"category_scores_gemma":[0.00006327206,0.00019269214,0.00006380079,0.00028490226,0.00017287779,0.000056528217,0.00009289159,0.00036006162,0.0000118886455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036976425,0.0000943323,0.0015354095,0.00023457172,0.00009774176,0.00003912228,0.00023514967,0.000002207407,0.9960544,0.0000040236996,0.00087150617,0.00046173474],"study_design_scores_gemma":[0.000976937,0.00013813461,0.00024363857,0.000036349826,0.00009144242,0.00001282327,0.00006407956,0.00033754253,0.9923756,0.000012855298,0.0054963166,0.00021424257],"about_ca_topic_score_codex":0.0000055592764,"about_ca_topic_score_gemma":4.886491e-7,"teacher_disagreement_score":0.0046248105,"about_ca_system_score_codex":0.000024657671,"about_ca_system_score_gemma":0.00020322221,"threshold_uncertainty_score":0.7857758},"labels":[],"label_agreement":null},{"id":"W3092249496","doi":"10.21577/0103-5053.20200202","title":"Synthesis and Biological Evaluation of Benzo[f]indole-4,9-diones N-Linked to Carbohydrate Chains as New Type of Antitumor Agents","year":2020,"lang":"en","type":"article","venue":"Journal of the Brazilian Chemical Society","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Air (Canada)","funders":"Fundação Oswaldo Cruz; Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Indole test; Chemistry; Carbohydrate; Combinatorial chemistry; Stereochemistry; Biochemistry","score_opus":0.2601216018620365,"score_gpt":0.4414256967134327,"score_spread":0.1813040948513962,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092249496","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99192214,0.0003824584,0.000019849802,0.0069558015,0.00036718673,0.00020066187,0.000022013486,0.0000056832905,0.00012421476],"genre_scores_gemma":[0.99703926,0.00023018946,0.00032518196,0.0021169134,0.00023956987,0.0000013991369,0.000001315726,0.0000092158125,0.000036933678],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986174,0.00025306482,0.00046109708,0.00015776254,0.00033789888,0.00017278966],"domain_scores_gemma":[0.9986328,0.00018399683,0.00044304744,0.000090515336,0.00031918258,0.00033045403],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074379245,0.00014065969,0.00038101885,0.00001934369,0.00007558577,0.000008406871,0.00035074912,0.00019620004,0.00028196286],"category_scores_gemma":[0.0009519084,0.0000935816,0.00030557608,0.00028318973,0.00021676367,0.000055629545,0.00015534353,0.0004042906,0.0000043847253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036889542,0.00016752568,0.014306088,0.0000441489,0.00031415588,0.0000023221291,0.00083087914,0.0001114439,0.97152454,0.00004283802,0.0101283975,0.0021587647],"study_design_scores_gemma":[0.001720263,0.00028550957,0.03701343,0.00010294444,0.00055758475,0.000023301576,0.00030445095,0.0038046674,0.9512591,0.00034704094,0.004400665,0.0001810551],"about_ca_topic_score_codex":0.0000067756437,"about_ca_topic_score_gemma":3.92356e-7,"teacher_disagreement_score":0.022707345,"about_ca_system_score_codex":0.000045411933,"about_ca_system_score_gemma":0.00019541758,"threshold_uncertainty_score":0.38161469},"labels":[],"label_agreement":null},{"id":"W3100358749","doi":"10.1080/07391102.2020.1846622","title":"Antimicrobial activity of<i>Plumbago indica</i>and ligand screening of plumbagin against methicillin-resistant<i>Staphylococcus aureus</i>","year":2020,"lang":"en","type":"article","venue":"Journal of Biomolecular Structure and Dynamics","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"University of Sri Jayewardenepura","keywords":"Plumbagin; Antimicrobial; DNA gyrase; Staphylococcus aureus; Minimum inhibitory concentration; Chemistry; Antibacterial activity; Microbiology; Docking (animal); Traditional medicine; Biology; Bacteria; Biochemistry; Escherichia coli; Botany; Medicine","score_opus":0.03903196942547921,"score_gpt":0.33916418690529815,"score_spread":0.30013221747981894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3100358749","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866637,0.0014126417,0.010109295,0.001014843,0.00023409483,0.00013608353,0.00035919237,0.0000068797426,0.0000632674],"genre_scores_gemma":[0.99584514,0.0007137388,0.0021524688,0.0011337022,0.00012081768,2.5479488e-7,0.000010424009,0.000019712481,0.0000037440475],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985403,0.00024009768,0.00053747563,0.00022024316,0.00023165726,0.00023021987],"domain_scores_gemma":[0.99850315,0.000103974526,0.0008225315,0.000101428916,0.00021178382,0.00025710868],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003309021,0.0002373663,0.00060997566,0.00014802936,0.000121915735,0.000025578369,0.0002263111,0.00032190568,0.000010083117],"category_scores_gemma":[0.000073849675,0.00020747975,0.00018148952,0.00027272422,0.0004630133,0.000115248215,0.00013329354,0.0007937915,1.1863912e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007834674,0.000076027565,0.010213518,0.00023528516,0.00049877155,0.00013777758,0.00049731106,0.00014078929,0.9781182,0.0001439202,0.00012444782,0.009030507],"study_design_scores_gemma":[0.0030793517,0.0005460562,0.009990654,0.00011761176,0.0005353764,0.000048998714,0.00014310787,0.0067561134,0.976355,0.0002542776,0.0018377424,0.0003356688],"about_ca_topic_score_codex":0.000013228209,"about_ca_topic_score_gemma":0.000015344045,"teacher_disagreement_score":0.009181435,"about_ca_system_score_codex":0.000018343317,"about_ca_system_score_gemma":0.00009643015,"threshold_uncertainty_score":0.84607786},"labels":[],"label_agreement":null},{"id":"W3112144762","doi":"10.1093/neuonc/noaa215.211","title":"CTNI-45. A PHASE 1B/2 CLINICAL STUDY OF NAPABUCASIN IN COMBINATION WITH TEMOZOLOMIDE FOR ADULT PATIENTS WITH RECURRENT OR PROGRESSED GLIOBLASTOMA MULTIFORME (GBM)","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Calgary","funders":"","keywords":"Temozolomide; Medicine; Internal medicine; Tolerability; Phases of clinical research; Adverse effect; Oncology; Surgery; Gastroenterology; Clinical trial; Chemotherapy","score_opus":0.1544762611913571,"score_gpt":0.4754712240521156,"score_spread":0.3209949628607585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112144762","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993385,0.000016720514,0.0000655335,0.0015101131,0.0006732818,0.0040612174,0.00012888775,0.000060726165,0.000098529694],"genre_scores_gemma":[0.99655575,0.000027769682,0.0003746501,0.0025358603,0.00011741186,0.00028717128,0.000049396305,0.00004421376,0.000007755885],"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","domain_scores_codex":[0.9967068,0.0010032775,0.00089588406,0.0006748632,0.00024118776,0.0004780054],"domain_scores_gemma":[0.9971283,0.001110559,0.0006513871,0.00018309717,0.0006278208,0.00029880495],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004223723,0.0003340485,0.0007970065,0.00014304723,0.0001439975,0.000014323874,0.00032304108,0.00030721398,0.000076693526],"category_scores_gemma":[0.00054360053,0.00023919054,0.000079205674,0.00049765594,0.0003395119,0.00014209059,0.000102478094,0.0008635406,0.000009115875],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.18932287,0.104536965,0.57284695,0.00026240578,0.0004900942,0.00045927608,0.0036509966,0.000052322455,0.007859595,0.00007666925,0.003154514,0.11728735],"study_design_scores_gemma":[0.38193816,0.42721942,0.073066704,0.00012141154,0.0008463511,0.000046045152,0.0031172426,0.019342294,0.011908315,0.000023825602,0.08135502,0.0010152267],"about_ca_topic_score_codex":0.00000893656,"about_ca_topic_score_gemma":0.0003648985,"teacher_disagreement_score":0.49978024,"about_ca_system_score_codex":0.00010643694,"about_ca_system_score_gemma":0.00030584287,"threshold_uncertainty_score":0.97539073},"labels":[],"label_agreement":null},{"id":"W3122808051","doi":"10.1200/jco.2021.39.3_suppl.477","title":"Effect of food on exposure to napabucasin: Data from two phase I studies.","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Pharmacology","score_opus":0.6275197424482802,"score_gpt":0.6712003606688983,"score_spread":0.043680618220618084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3122808051","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98262143,0.003493529,0.0000612624,0.003910557,0.008189238,0.00016882394,0.00022175998,0.000007940089,0.0013254775],"genre_scores_gemma":[0.9898292,0.001398503,0.0006487349,0.0055730417,0.002370526,0.0000023463924,0.000024116578,0.00001682271,0.0001367368],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99319136,0.0038236044,0.0020292166,0.00038239025,0.00028991397,0.00028352524],"domain_scores_gemma":[0.9840068,0.013093831,0.0014210374,0.00046448628,0.00055312406,0.00046071768],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0060471594,0.00021446864,0.0018129469,0.00008997652,0.00008378907,0.000008707091,0.0007321423,0.0004159155,0.0007606592],"category_scores_gemma":[0.007180624,0.00015588218,0.0004043858,0.0002071957,0.0002899954,0.000115044124,0.000425885,0.0016362651,0.00006422631],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.037030857,0.011269086,0.038830973,0.00011696017,0.008496553,0.0043665464,0.00047745235,0.00017953893,0.02561277,0.0002746106,0.13301027,0.7403344],"study_design_scores_gemma":[0.05070926,0.11758284,0.0077733127,0.00020911002,0.002104684,0.00020453465,0.0003704118,0.00020411998,0.07877243,0.00062330323,0.74108374,0.00036222854],"about_ca_topic_score_codex":0.0000032586217,"about_ca_topic_score_gemma":0.00003508177,"teacher_disagreement_score":0.7399722,"about_ca_system_score_codex":0.0000763437,"about_ca_system_score_gemma":0.0006373121,"threshold_uncertainty_score":0.85963964},"labels":[],"label_agreement":null},{"id":"W3129058379","doi":"10.1016/j.jep.2021.113896","title":"Phytochemical constituents, distributions and traditional usages of Arnebia euchroma: A review","year":2021,"lang":"en","type":"review","venue":"Journal of Ethnopharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":94,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministry of Environment - Saskatchewan","keywords":"Phytochemical; Traditional medicine; Biology; Medicine","score_opus":0.42982479592959605,"score_gpt":0.5431475198763285,"score_spread":0.11332272394673243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3129058379","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011336925,0.9938506,0.00004064958,0.00045788375,0.0027223704,0.0004890113,0.0009133736,0.0000103085995,0.00038209543],"genre_scores_gemma":[0.0009354338,0.99717754,0.00024511176,0.0006454005,0.0006799532,0.000034292614,0.00016201459,0.000028882672,0.00009135535],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9958002,0.0013725923,0.0017887694,0.00035505358,0.00028737716,0.00039599763],"domain_scores_gemma":[0.9954312,0.0014194709,0.00208921,0.0001543993,0.00052794104,0.00037779327],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011357206,0.0004858249,0.0031282075,0.00023134694,0.00015312785,0.000013712058,0.00048819554,0.00071546144,0.0026508279],"category_scores_gemma":[0.00035410578,0.00040383948,0.00097328314,0.00043369696,0.0010882737,0.00012243658,0.00017989463,0.0024522066,0.000012462268],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015916905,0.0032786957,0.00018223503,0.07191533,0.007863652,0.00249457,0.00006458912,0.0000012945425,0.009595759,0.0027946092,0.38754156,0.51410854],"study_design_scores_gemma":[0.0011480062,0.00018275352,0.00002889607,0.014205948,0.0072134743,0.0014267355,0.000009759291,0.0000021932497,0.0005855742,0.00007207817,0.9748123,0.00031225584],"about_ca_topic_score_codex":0.000001196854,"about_ca_topic_score_gemma":4.9805385e-7,"teacher_disagreement_score":0.58727074,"about_ca_system_score_codex":0.00016154545,"about_ca_system_score_gemma":0.0010961804,"threshold_uncertainty_score":0.9998492},"labels":[],"label_agreement":null},{"id":"W3134361672","doi":"10.4103/1735-5362.310520","title":"The effects of Benjakul extract and its isolated compounds on cell cycle arrest and apoptosis in human non-small cell lung cancer cell line NCI-H226","year":2021,"lang":"en","type":"article","venue":"Research in Pharmaceutical Sciences","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Plumbagin; Cytotoxicity; Apoptosis; Cell cycle; Flow cytometry; Sulforhodamine B; Population; Molecular biology; Cell cycle checkpoint; Chemistry; Cell; Cell culture; Biology; Biochemistry; In vitro; Medicine; Botany","score_opus":0.1723257655393342,"score_gpt":0.5065358180285481,"score_spread":0.33421005248921387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3134361672","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97431904,0.01666668,0.000003106133,0.0011095663,0.00049114175,0.0006293225,0.000019546853,0.000011669821,0.006749931],"genre_scores_gemma":[0.98140377,0.017809782,0.000024367724,0.00026702054,0.00009308099,0.00006408397,0.000003012284,0.0000143841235,0.00032050858],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9960775,0.0013318046,0.00041677887,0.00065084023,0.00050962466,0.0010135019],"domain_scores_gemma":[0.99587625,0.00333593,0.00009399594,0.00014546562,0.0001567015,0.00039162656],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002983848,0.00023799701,0.0003275407,0.00018411079,0.00085113297,0.00012737949,0.0005029071,0.00020601136,0.00014509982],"category_scores_gemma":[0.00009736907,0.00018028346,0.00005471438,0.0010018676,0.0011855856,0.00017106307,0.00041024503,0.0015170637,0.000005617518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002587627,0.0015963861,0.059607334,0.00093971164,0.000028123633,0.00012541696,0.0004760264,0.00017525766,0.93233496,0.0003200835,0.00038448186,0.0037534728],"study_design_scores_gemma":[0.002763862,0.00048161394,0.0119769955,0.00021420457,0.000039642247,0.0000031569782,0.00036580692,0.06371005,0.91731954,0.00022677805,0.002633408,0.0002649698],"about_ca_topic_score_codex":0.00021791489,"about_ca_topic_score_gemma":0.0002890201,"teacher_disagreement_score":0.063534796,"about_ca_system_score_codex":0.00012746047,"about_ca_system_score_gemma":0.0002294146,"threshold_uncertainty_score":0.73517466},"labels":[],"label_agreement":null},{"id":"W3138591322","doi":"10.1016/j.crbiot.2021.03.002","title":"Natural products and their applications","year":2021,"lang":"en","type":"article","venue":"Current Research in Biotechnology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Natural (archaeology); Computer science; Geography; Archaeology","score_opus":0.3565524167949689,"score_gpt":0.5430192776929736,"score_spread":0.18646686089800474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3138591322","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91306746,0.055620555,0.00017868841,0.027481105,0.0011540975,0.00080487464,0.000043911514,0.00014200322,0.0015072846],"genre_scores_gemma":[0.992777,0.006455591,0.00012361955,0.00008523564,0.00014495588,0.00015164618,0.00003142872,0.000009789158,0.000220736],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982907,0.00040045657,0.00017496821,0.0004916801,0.00010264998,0.0005395407],"domain_scores_gemma":[0.99919856,0.00020756463,0.000030673433,0.00027903987,0.00020666826,0.000077526354],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072381843,0.00012635152,0.00017117792,0.00032682603,0.00024082027,0.000023895484,0.00027965,0.00029220353,0.00008615087],"category_scores_gemma":[0.00014614924,0.00010763429,0.000025684483,0.0011006441,0.0008806786,0.00005457562,0.00045115553,0.0021658083,0.000080871396],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046867328,0.0007540565,0.008140667,0.00017356375,0.000040434545,0.00005787211,0.00012206219,5.298881e-7,0.37865892,0.041074697,0.003802676,0.56712765],"study_design_scores_gemma":[0.00045531167,0.000032539483,0.0024052502,0.000021814609,0.0000033423728,0.00005834849,0.00022357154,0.00024368135,0.2744896,0.004760607,0.7171853,0.00012061494],"about_ca_topic_score_codex":0.0000043676478,"about_ca_topic_score_gemma":0.000022523582,"teacher_disagreement_score":0.71338266,"about_ca_system_score_codex":0.000070994145,"about_ca_system_score_gemma":0.00013926676,"threshold_uncertainty_score":0.94094795},"labels":[],"label_agreement":null},{"id":"W3144339028","doi":"10.1021/acs.joc.1c00165","title":"Unveiling KuQuinone Redox Species: An Electrochemical and Computational Cross Study","year":2021,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Università degli Studi di Roma Tor Vergata","keywords":"Chemistry; Redox; Electrochemistry; Molecule; Hydrogen bond; Computational chemistry; Electrolyte; Solvent; Supporting electrolyte; Photochemistry; Combinatorial chemistry; Inorganic chemistry; Organic chemistry; Physical chemistry; Electrode","score_opus":0.0746756550261405,"score_gpt":0.41346909684865546,"score_spread":0.338793441822515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3144339028","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978722,0.0007772257,0.00023385599,0.00037308584,0.00016014563,0.000042584925,0.00000468989,0.000008959337,0.00052727596],"genre_scores_gemma":[0.99837524,0.00013432563,0.00014138091,0.0002535369,0.00044570738,3.3583748e-7,0.000005592575,0.0000116512165,0.00063221314],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904907,0.00015986513,0.00031336534,0.00012304077,0.00017895055,0.00017572836],"domain_scores_gemma":[0.99908483,0.00021034614,0.00019845841,0.00010701001,0.00026032128,0.000139047],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006021058,0.000118272044,0.0001921884,0.000010864509,0.00021608341,0.00003967118,0.0002234829,0.00009279281,0.0027402344],"category_scores_gemma":[0.00008288775,0.00008953382,0.000046617475,0.00012638944,0.0001720408,0.000078256446,0.00009116477,0.0007146112,0.0000046631203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020469919,0.0006239492,0.01891619,0.000019841296,0.00019129398,0.00012030848,0.0006608541,0.000040586805,0.9787726,0.0000045802244,0.00033624264,0.000108869936],"study_design_scores_gemma":[0.0022980415,0.0001636828,0.024497723,0.000014903323,0.00021908066,0.0025487475,0.0025528597,0.00033929158,0.9648365,0.00027152567,0.0020928557,0.00016483093],"about_ca_topic_score_codex":3.704091e-7,"about_ca_topic_score_gemma":9.614411e-7,"teacher_disagreement_score":0.0139361285,"about_ca_system_score_codex":0.000053562766,"about_ca_system_score_gemma":0.00016593214,"threshold_uncertainty_score":0.9981714},"labels":[],"label_agreement":null},{"id":"W3146190083","doi":"10.21203/rs.3.rs-223104/v1","title":"Synthesis, characterization and antimicrobial properties of two derivatives of pyrrolidine-2,5-dione fused at positions-3,4 to a dibenzobarrelene backbone","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Deutscher Akademischer Austauschdienst","keywords":"Chemistry; Antimicrobial; Pyrrolidine; Aniline; Stereochemistry; Proton NMR; Chemical structure; Combinatorial chemistry; Organic chemistry","score_opus":0.21910278992522775,"score_gpt":0.467265804241969,"score_spread":0.24816301431674126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3146190083","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99490184,0.0010086106,0.00019632229,0.0014756628,0.0003053579,0.0011157251,0.0008562581,0.000027595317,0.0001126602],"genre_scores_gemma":[0.9963831,0.0023300059,0.00027602975,0.00009251855,0.00015509245,0.00016550254,0.00031015102,0.00003983279,0.00024777904],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965164,0.0014515715,0.0005417332,0.00058691995,0.00042811132,0.00047526462],"domain_scores_gemma":[0.9978278,0.00028448648,0.0002510212,0.00035350036,0.0010567991,0.00022635593],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009651688,0.00029309018,0.000678302,0.0004275239,0.0003205982,0.000054740118,0.0003253425,0.0003620888,0.00046571053],"category_scores_gemma":[0.0002855513,0.00027568816,0.00014590849,0.00035554875,0.0005667548,0.00010623911,0.0015183772,0.0009092993,0.000010769375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008020789,0.00072911865,0.012023312,0.002545613,0.00031497888,0.000023118833,0.0017139456,0.0000652751,0.98005533,0.000071409886,0.00023099939,0.0014247991],"study_design_scores_gemma":[0.00069776294,0.00014265817,0.039812177,0.0016896657,0.000083911975,0.000011944221,0.00026498287,0.00035140556,0.95601654,0.000014074469,0.00066377077,0.00025108233],"about_ca_topic_score_codex":0.00009102765,"about_ca_topic_score_gemma":0.000051589268,"teacher_disagreement_score":0.027788866,"about_ca_system_score_codex":0.00013461478,"about_ca_system_score_gemma":0.00026348195,"threshold_uncertainty_score":0.99996954},"labels":[],"label_agreement":null},{"id":"W3153630040","doi":"10.1016/j.tranon.2021.101061","title":"ROS mediated apoptotic pathways in primary effusion lymphoma: Comment on induction of apoptosis by Shikonin through ROS-mediated intrinsic and extrinsic pathways in primary effusion lymphoma","year":2021,"lang":"en","type":"article","venue":"Translational Oncology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Microsemi (Canada)","funders":"","keywords":"Apoptosis; Primary effusion lymphoma; Interconnectivity; Lymphoma; Cancer research; Medicine; Effusion; Mechanism (biology); Cell biology; Immunology; Chemistry; Biology; Biochemistry; Surgery","score_opus":0.07916711223718204,"score_gpt":0.34348702748875976,"score_spread":0.2643199152515777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3153630040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898428,0.0013641112,0.00010020715,0.0042802077,0.0008948756,0.0007607657,0.00034794587,0.000059130376,0.00235001],"genre_scores_gemma":[0.99017465,0.0018802754,0.00035473445,0.0052712807,0.00010836258,0.000097087875,0.0020477967,0.000040729978,0.00002507122],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9958191,0.001434996,0.001049471,0.0007194708,0.00041785423,0.00055909227],"domain_scores_gemma":[0.997366,0.0017397187,0.00035930594,0.00020453293,0.00015310114,0.00017730378],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009046426,0.00043128827,0.00086391193,0.00032917445,0.00019616443,0.000016083372,0.00020967294,0.0008358934,0.00026449957],"category_scores_gemma":[0.00008729265,0.0004418001,0.00012918486,0.0007983829,0.00037065364,0.0002501196,0.00012488272,0.0006005392,0.000026617654],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0045028348,0.010570548,0.046358168,0.00032795357,0.00021580956,0.00024050484,0.002942697,0.000242024,0.7554853,0.0020801127,0.0017808599,0.17525321],"study_design_scores_gemma":[0.03914844,0.0015217736,0.79526025,0.0002940392,0.0002050893,0.000089770976,0.00042933194,0.0020100097,0.12246041,0.0012797801,0.036343955,0.0009571198],"about_ca_topic_score_codex":0.00009452642,"about_ca_topic_score_gemma":0.00008733335,"teacher_disagreement_score":0.7489021,"about_ca_system_score_codex":0.00084190705,"about_ca_system_score_gemma":0.00072763424,"threshold_uncertainty_score":0.99980336},"labels":[],"label_agreement":null},{"id":"W3159277719","doi":"","title":"Role of NADPH:cytochrome P450 reductase in RH1 activation","year":2005,"lang":"en","type":"article","venue":"","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Dicoumarol; Reductase; Enzyme; Biochemistry; Cytotoxicity; Cytochrome P450 reductase; Transfection; Cytochrome P450; Biology; In vitro; Cytochrome c; NAD+ kinase; Apoptosis; Gene","score_opus":0.09552476335230177,"score_gpt":0.43171521043598593,"score_spread":0.3361904470836842,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3159277719","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96732855,0.00018598145,0.000015996478,0.00071746146,0.00008001511,0.00019583397,0.000016959471,0.000032399894,0.03142681],"genre_scores_gemma":[0.99770796,0.000066317276,0.0004053206,0.000680002,0.00016414408,0.000014665042,0.000018403138,0.000010741415,0.00093245343],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990653,0.00012604441,0.00027051126,0.00019629685,0.00009770595,0.0002441859],"domain_scores_gemma":[0.9995654,0.00007907223,0.00009951198,0.00011775482,0.00005202634,0.00008622407],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00023954353,0.00012480328,0.00017812406,0.00013117144,0.00006284074,0.00000668989,0.00015149835,0.00015975957,0.002985252],"category_scores_gemma":[0.000025660975,0.0001167143,0.00005551747,0.00020668816,0.000102487254,0.0001766148,0.000048875416,0.00030667608,0.0000912975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015277578,0.00052866456,0.0061652814,0.000011695219,0.00003650995,0.0000026714472,0.00037739874,0.00009976135,0.966632,0.002090232,0.0013980995,0.02250492],"study_design_scores_gemma":[0.0011823071,0.000071231014,0.052957185,0.000014011761,0.000019447705,0.00000723311,0.00046872656,0.0020751632,0.8513454,0.00068897684,0.09099803,0.00017228904],"about_ca_topic_score_codex":0.000071264185,"about_ca_topic_score_gemma":0.000050265327,"teacher_disagreement_score":0.11528659,"about_ca_system_score_codex":0.00007114989,"about_ca_system_score_gemma":0.000048294554,"threshold_uncertainty_score":0.9979262},"labels":[],"label_agreement":null},{"id":"W3163084951","doi":"","title":"Metabolomic Profiling and Biological Investigation of Tabebuia aurea (Silva Manso) Leaves, Family Bignoniaceae","year":2021,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Bignoniaceae; Ethyl acetate; Chemical constituents; Traditional medicine; Chemistry; Kaempferol; Rutin; Biology; Antioxidant; Botany; Biochemistry; Chromatography; Flavonoid","score_opus":0.10589604964794981,"score_gpt":0.3791116478794355,"score_spread":0.2732155982314857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3163084951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9783333,0.01943433,0.00061002007,0.0006331877,0.00041211295,0.0001242071,0.0000150041205,0.00002428852,0.00041352992],"genre_scores_gemma":[0.978495,0.019782942,0.0004369016,0.0005545673,0.00022373171,0.000004874131,0.000019679159,0.000015779178,0.0004665004],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975294,0.0005259269,0.00038653583,0.0002785882,0.00013538008,0.0011441773],"domain_scores_gemma":[0.9992336,0.000117243406,0.00023686394,0.00010116065,0.00016100136,0.000150108],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014863691,0.00019812684,0.00032677312,0.000096566226,0.0002747989,0.000026066704,0.00017256323,0.00024665406,0.000076183984],"category_scores_gemma":[0.000063641506,0.0001666528,0.000114341725,0.0002244003,0.00034546078,0.00013148552,0.00007335834,0.002047368,0.000010212046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022373008,0.00013860661,0.14937818,0.000027256943,0.0005428871,0.00003140292,0.0001733501,0.000020395264,0.7824283,0.059537165,0.00017053248,0.0073281536],"study_design_scores_gemma":[0.0065698354,0.0011920533,0.17226025,0.00008506479,0.00076444546,0.002374216,0.007342863,0.0009654956,0.61025447,0.17707181,0.020082816,0.0010366942],"about_ca_topic_score_codex":0.000010863598,"about_ca_topic_score_gemma":0.000034375767,"teacher_disagreement_score":0.17217389,"about_ca_system_score_codex":0.00015691016,"about_ca_system_score_gemma":0.0011296528,"threshold_uncertainty_score":0.88949096},"labels":[],"label_agreement":null},{"id":"W3168266824","doi":"10.3390/cancers13112840","title":"A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Terry Fox Foundation; University of Sharjah","keywords":"Apoptosis; Thioredoxin; In vivo; Thioredoxin reductase; Cancer research; Cell cycle; PI3K/AKT/mTOR pathway; Cell growth; Drug discovery; DNA damage; Cell cycle checkpoint; Pharmacology; Programmed cell death; Cancer; Cancer cell; Protein kinase B; Chemistry; Biology; Bioinformatics; Biochemistry; Oxidative stress; DNA","score_opus":0.13081049714007265,"score_gpt":0.3976968113736951,"score_spread":0.26688631423362247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3168266824","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9589133,0.02764141,0.00034154177,0.00035941476,0.0024025626,0.00015435624,0.00032509823,0.00005266362,0.009809629],"genre_scores_gemma":[0.9895603,0.006997377,0.00046733452,0.0017891927,0.00036044253,0.000044487686,0.000029035302,0.000024097493,0.0007277148],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988331,0.00012991046,0.00018608788,0.00036474515,0.00010951568,0.00037659658],"domain_scores_gemma":[0.9993489,0.00011899853,0.00009976589,0.00009852835,0.00014332402,0.00019049748],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00019334031,0.00019309718,0.00027769624,0.000023495888,0.000271902,0.000027019354,0.00011241544,0.00011202559,0.0016710559],"category_scores_gemma":[0.000030729963,0.00019116915,0.000068762005,0.00017751504,0.00017291981,0.00011798688,0.00009712509,0.00034446988,0.000009056582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010938492,0.00009173435,0.014184711,0.00008311,0.00029345174,0.00008036047,0.0013988855,0.00040638886,0.9719798,0.0018260599,0.003306718,0.0062393914],"study_design_scores_gemma":[0.002879164,0.000043522174,0.010869652,0.00003028706,0.00023841226,0.000017294537,0.0024623612,0.0023514822,0.6108378,0.00010792259,0.36964667,0.0005153858],"about_ca_topic_score_codex":0.000469798,"about_ca_topic_score_gemma":0.00033675632,"teacher_disagreement_score":0.36633995,"about_ca_system_score_codex":0.0002523334,"about_ca_system_score_gemma":0.00048170082,"threshold_uncertainty_score":0.99924153},"labels":[],"label_agreement":null},{"id":"W3183131010","doi":"10.1016/j.cbi.2021.109574","title":"Interactions of the antioxidant enzymes NAD(P)H: Quinone oxidoreductase 1 (NQO1) and NRH: Quinone oxidoreductase 2 (NQO2) with pharmacological agents, endogenous biochemicals and environmental contaminants","year":2021,"lang":"en","type":"review","venue":"Chemico-Biological Interactions","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":64,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Quinone; Chemistry; NAD+ kinase; Antioxidant; Oxidative stress; Oxidoreductase; Reactive oxygen species; Biochemistry; Enzyme","score_opus":0.25587667413880183,"score_gpt":0.4384849016516901,"score_spread":0.18260822751288824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3183131010","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.38393053,0.61102134,0.0000070311876,0.00014769027,0.0010752326,0.0011041082,0.0022629735,0.000056651843,0.00039443825],"genre_scores_gemma":[0.40160957,0.5965571,0.000098020726,0.00026301757,0.00023255456,0.00021874506,0.000596429,0.000043342436,0.00038122493],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9955389,0.0009337163,0.001219228,0.0012865964,0.0002457233,0.0007758371],"domain_scores_gemma":[0.9966522,0.0012474515,0.0010208904,0.00048399618,0.00010469617,0.00049079856],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00032324545,0.0010271866,0.0021068596,0.00017512243,0.00063407526,0.0000766109,0.00062462786,0.00072845025,0.002560796],"category_scores_gemma":[0.00018464927,0.0006401403,0.0006454806,0.00038664957,0.0024240452,0.00019466018,0.00087875564,0.0024637384,0.000024959729],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042596148,0.004966791,0.0012134083,0.0014505464,0.0038906415,0.00045289798,0.00039371007,0.0000012944889,0.901173,0.00030392452,0.007707362,0.07802048],"study_design_scores_gemma":[0.0014637479,0.00031138875,0.00023522081,0.0019814842,0.0033861792,0.0056057395,0.0010002955,0.000021637468,0.15965042,0.000022471708,0.8252975,0.0010239132],"about_ca_topic_score_codex":0.000035115165,"about_ca_topic_score_gemma":0.000009496017,"teacher_disagreement_score":0.8175901,"about_ca_system_score_codex":0.00027794065,"about_ca_system_score_gemma":0.00016860064,"threshold_uncertainty_score":0.99983764},"labels":[],"label_agreement":null},{"id":"W3186638495","doi":"10.82308/30663","title":"Synthesis of novel chloroquine derivatives and insights into the interactions of a resistance protein","year":2021,"lang":"en","type":"article","venue":"eScholarship@McGill (McGill)","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McGill University","keywords":"Chloroquine; Resistance (ecology); Malaria; Biology; Ecology","score_opus":0.076396163469825,"score_gpt":0.3529631361310335,"score_spread":0.27656697266120844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3186638495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98680466,0.00086768955,0.0000030177846,0.0003189684,0.00026537426,0.00031011875,0.0002353979,0.000028934535,0.011165836],"genre_scores_gemma":[0.9971203,0.0003410197,0.0010435795,0.0002667864,0.000018832105,0.000080314036,0.000007695808,0.000027344166,0.0010941249],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981119,0.0005215231,0.00050657656,0.0004014626,0.00020397027,0.0002545687],"domain_scores_gemma":[0.998046,0.0007755667,0.0003525861,0.00032032773,0.00037775713,0.00012776976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044736304,0.00024449208,0.0003938815,0.000105384584,0.0006688471,0.000015040183,0.00029236457,0.00016228925,0.00022610325],"category_scores_gemma":[0.00079652306,0.00019718365,0.0001334121,0.0004557121,0.00046924382,0.00031141794,0.00026625715,0.00067644764,0.0000065769814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026198852,0.0006465868,0.0002679756,0.0001781399,0.0003136076,0.000020257125,0.00009706009,0.0000066012203,0.925093,0.061746288,0.0000052751175,0.011363235],"study_design_scores_gemma":[0.00071983173,0.000051010134,0.0028560297,0.00019671099,0.00011925574,0.000011637474,0.0005573009,0.00004607183,0.91852903,0.004115917,0.07259449,0.00020272547],"about_ca_topic_score_codex":0.000041053838,"about_ca_topic_score_gemma":0.00049529,"teacher_disagreement_score":0.07258922,"about_ca_system_score_codex":0.00007930872,"about_ca_system_score_gemma":0.00003975987,"threshold_uncertainty_score":0.8040916},"labels":[],"label_agreement":null},{"id":"W3186813330","doi":"10.3390/md19080408","title":"Anti-Cancer and Anti-Inflammatory Activities of Three New Chromone Derivatives from the Marine-Derived Penicillium citrinum","year":2021,"lang":"en","type":"article","venue":"Marine Drugs","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Beef Cattle Research Council; Ministry of Science and Technology, Taiwan","keywords":"Penicillium citrinum; Chromone; Apoptosis; Chemistry; Superoxide; IC50; Western blot; Stereochemistry; HeLa; Cytotoxic T cell; Cancer cell; Biochemistry; Biology; Cancer; Cell; In vitro; Gene; Enzyme","score_opus":0.06532037200022088,"score_gpt":0.3517045169667382,"score_spread":0.2863841449665173,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3186813330","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924388,0.0011665086,0.000046374054,0.0022529776,0.0006605943,0.00021954962,0.000120029166,0.00004877016,0.0030464127],"genre_scores_gemma":[0.99395555,0.0026183368,0.0001972514,0.000831514,0.00044877792,0.000017284883,0.000068277586,0.000030320029,0.0018326868],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9985437,0.00021037314,0.00032263022,0.00039728894,0.00018255405,0.00034345235],"domain_scores_gemma":[0.99882025,0.000445025,0.00021456662,0.00029257868,0.0000904949,0.00013709728],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00019466928,0.00028212368,0.00046947238,0.000045212248,0.0002498031,0.00004455226,0.00028242578,0.0001614356,0.00358076],"category_scores_gemma":[0.000041254025,0.00022652363,0.00012272263,0.00018668591,0.00044882804,0.00016010202,0.00091482233,0.000504366,0.000010962155],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001303543,0.00016789242,0.5459478,0.00005279339,0.00054181396,0.000039882303,0.0008620288,0.000010652344,0.4223598,0.0002998,0.0018726621,0.027714558],"study_design_scores_gemma":[0.0014763232,0.000022011058,0.5607395,0.000020748974,0.0001368358,0.000006554923,0.00060938695,0.0001602246,0.41834673,0.00047918636,0.017774798,0.00022769644],"about_ca_topic_score_codex":0.0009957197,"about_ca_topic_score_gemma":0.0006213913,"teacher_disagreement_score":0.02748686,"about_ca_system_score_codex":0.000033758693,"about_ca_system_score_gemma":0.00019129727,"threshold_uncertainty_score":0.9973301},"labels":[],"label_agreement":null},{"id":"W3205879297","doi":"10.29169/1927-5951.2020.10.02.1","title":"Review of Medicinal Applications, Phytochemistry and Pharmacological Properties of Aristea ecklonii","year":2020,"lang":"en","type":"article","venue":"Journal of Pharmacy and Nutrition Sciences","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"University of Fort Hare","keywords":"Phytochemistry; Phytochemical; Traditional medicine; Antifungal; Web of science; Medicine; Ethnobotany; Medicinal plants; Dermatology","score_opus":0.280657715228794,"score_gpt":0.47502085195222754,"score_spread":0.19436313672343353,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3205879297","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7294828,0.25905013,0.000114450406,0.010437628,0.000117115196,0.00034707956,0.00003099966,0.0000065708227,0.00041318804],"genre_scores_gemma":[0.86487865,0.1317346,0.0002415601,0.0029462676,0.00018188212,0.000009157387,7.4549774e-7,0.0000022100196,0.0000048942975],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988739,0.00014622178,0.0005204114,0.00013765432,0.00020792712,0.000113887196],"domain_scores_gemma":[0.9989556,0.000088795445,0.0005275998,0.000025565841,0.00022773788,0.0001747073],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007578746,0.0000985721,0.00033364023,0.00004911405,0.00012593827,0.000008566251,0.00019434489,0.000039781236,0.00020308772],"category_scores_gemma":[0.000057785517,0.000069125825,0.00006772105,0.00022320489,0.0009237266,0.00017479404,0.000049920116,0.0002813937,5.687324e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071127596,0.0006057401,0.006166454,0.009423585,0.00011841699,0.0000106255675,0.00020285662,0.0000012897544,0.9681375,0.00012899777,0.006112455,0.008380809],"study_design_scores_gemma":[0.0033265615,0.00062272686,0.00030277198,0.0012561245,0.0006307068,0.0002290529,0.0004996228,0.0004002458,0.8594761,0.00017242713,0.13293128,0.00015242802],"about_ca_topic_score_codex":0.0000012506943,"about_ca_topic_score_gemma":4.8936325e-8,"teacher_disagreement_score":0.13539584,"about_ca_system_score_codex":0.000006805429,"about_ca_system_score_gemma":0.00007451844,"threshold_uncertainty_score":0.3403509},"labels":[],"label_agreement":null},{"id":"W4200149034","doi":"10.26434/chemrxiv-2021-l9gq4","title":"Optimization of N-piperidinyl-benzimidazolone derivatives as potent and selective inhibitors of 8-Oxo Guanine DNA Glycosylase 1","year":2021,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Vetenskapsrådet; Fondation pour la Recherche Médicale; Crafoordska Stiftelsen; Cancerfonden; European Federation of Pharmaceutical Industries and Associations; Innovative Medicines Initiative; Pain Relief Foundation; Diamond Light Source; McGill University; European Commission; Torsten Söderbergs Stiftelse","keywords":"Guanine; DNA glycosylase; Chemistry; DNA; Linker; DNA repair; Base excision repair; DNA damage; Deoxyguanosine; Transversion; Biochemistry; Enzyme; Stereochemistry; Gene; Nucleotide; Mutation","score_opus":0.07326965091732478,"score_gpt":0.37985689519823623,"score_spread":0.30658724428091144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200149034","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937362,0.0020937864,0.00084596017,0.0002694549,0.0008332543,0.00046412356,0.000049257866,0.000039224447,0.0016687223],"genre_scores_gemma":[0.99550015,0.0023520577,0.0014281031,0.0001614361,0.00015830593,0.00003996407,0.000180511,0.000040275718,0.00013922746],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99802536,0.0002729975,0.00059695914,0.00060504786,0.00020194374,0.00029768405],"domain_scores_gemma":[0.99821025,0.00017958881,0.0006680754,0.00027297882,0.0005029857,0.0001660926],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003055502,0.00040478254,0.00075212977,0.0001671511,0.000116145224,0.000024340477,0.0002450103,0.0006275839,0.000464956],"category_scores_gemma":[0.00019746496,0.00041313202,0.00020162041,0.00027811297,0.00050144043,0.00009732095,0.0006477591,0.0008457973,0.0000023934597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010639096,0.0020307836,0.017582232,0.0018398026,0.0019196837,0.00010737243,0.0039120214,0.0183373,0.94780564,0.0004754348,0.0014661402,0.0034596706],"study_design_scores_gemma":[0.0011737687,0.00016638526,0.0036230145,0.00023305134,0.0003021997,0.000020339512,0.00050251913,0.004310213,0.98868734,0.00019312405,0.00041441116,0.00037360756],"about_ca_topic_score_codex":0.000046913883,"about_ca_topic_score_gemma":0.0000055171004,"teacher_disagreement_score":0.040881716,"about_ca_system_score_codex":0.00007492286,"about_ca_system_score_gemma":0.000247149,"threshold_uncertainty_score":0.99983203},"labels":[],"label_agreement":null},{"id":"W4237051755","doi":"10.1002/0471203076.emm1059","title":"Elongins","year":2002,"lang":"en","type":"other","venue":"Wiley Encyclopedia of Molecular Medicine","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Library science; Encyclopedia; Sociology; Media studies; Computer science","score_opus":0.05623663735266572,"score_gpt":0.3777076912773049,"score_spread":0.3214710539246392,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4237051755","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005832275,0.024268026,0.00025833948,0.0005966977,0.0028211786,0.00055160385,0.00011581705,0.0001528073,0.9706523],"genre_scores_gemma":[0.008033125,0.06635095,0.00053903204,0.0020662004,0.001975029,0.00008118901,0.00020373116,0.0006177621,0.920133],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99808925,0.00022860602,0.00043927625,0.00045497867,0.00036886724,0.00041901515],"domain_scores_gemma":[0.9987351,0.000083823514,0.0004147158,0.00042929102,0.000064426,0.0002726812],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022545512,0.00045476243,0.00076483976,0.00038071687,0.000044085315,0.0000025191077,0.0004595739,0.00070652587,0.04418879],"category_scores_gemma":[0.00011322967,0.00038498142,0.0001594602,0.00026540234,0.00059041067,0.000019870386,0.000096061456,0.00071942917,0.00031084943],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022555814,0.00022503636,0.0007354641,0.00021428896,0.00032633188,0.0003777156,0.00011253638,0.0000030047743,0.0039757653,0.00037298858,0.9694884,0.024145909],"study_design_scores_gemma":[0.0013551807,0.00018509282,0.00016098046,0.000493416,0.00039001848,0.000021223861,0.00002428228,0.000034340657,0.0006177788,0.00006619281,0.99630743,0.00034404005],"about_ca_topic_score_codex":0.00014361255,"about_ca_topic_score_gemma":0.000022267384,"teacher_disagreement_score":0.050519325,"about_ca_system_score_codex":0.00003115694,"about_ca_system_score_gemma":0.000045437468,"threshold_uncertainty_score":0.9998602},"labels":[],"label_agreement":null},{"id":"W4239161827","doi":"10.1002/chin.200310217","title":"Synthesis of (+)‐Puraquinonic Acid.","year":2003,"lang":"en","type":"article","venue":"ChemInform","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Combinatorial chemistry; Stereochemistry","score_opus":0.0931004842686371,"score_gpt":0.3904708533108143,"score_spread":0.29737036904217723,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4239161827","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.20675552,0.00036438616,0.0000032096739,0.00006403384,0.00040740214,0.00009989101,0.000019832307,0.00003214777,0.79225355],"genre_scores_gemma":[0.9948076,0.00013345982,0.00007552052,0.0002618074,0.00003913063,0.000019088111,0.0000040456052,0.000009773365,0.0046495805],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930054,0.000004156795,0.00022709719,0.0001244024,0.00008963962,0.0002541608],"domain_scores_gemma":[0.99943733,0.00013610882,0.00011101186,0.00015027293,0.000058096346,0.000107173546],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002579304,0.00012641032,0.00019188235,0.000046165474,0.00008034413,0.000006046047,0.00016827857,0.0001596087,0.003335069],"category_scores_gemma":[0.00014238109,0.000112982365,0.000101847116,0.00013258375,0.00016098471,0.00008369818,0.000030698204,0.00020539506,0.00013697501],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026887664,0.00084762776,0.020625222,0.00042389476,0.00059197674,0.000042049738,0.0008485149,0.00000241427,0.3361993,0.024153046,0.06626135,0.5497357],"study_design_scores_gemma":[0.0002850494,0.000019934194,0.0005800376,0.000009043528,0.00004071714,0.0000140389175,0.00009790128,0.000008051216,0.7647014,0.00011939494,0.23402308,0.00010133932],"about_ca_topic_score_codex":0.0000019255053,"about_ca_topic_score_gemma":9.123469e-7,"teacher_disagreement_score":0.7880521,"about_ca_system_score_codex":0.00003550276,"about_ca_system_score_gemma":0.000057614,"threshold_uncertainty_score":0.997576},"labels":[],"label_agreement":null},{"id":"W4240094159","doi":"10.3410/f.1006781.202809","title":"Faculty Opinions recommendation of Synthesis and biological evaluation of an indomethacin library reveals a new class of angiogenesis-related kinase inhibitors.","year":2004,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Class (philosophy); Angiogenesis; Kinase; Computational biology; Pharmacology; Cancer research; Medicine; Bioinformatics; Computer science; Chemistry; Biology; Biochemistry; Artificial intelligence","score_opus":0.144463496565024,"score_gpt":0.45010732397085884,"score_spread":0.30564382740583484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240094159","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00096286804,0.003607692,0.0000042065044,0.0340527,0.0006532796,0.0015542171,0.9591054,0.000022902925,0.0000367659],"genre_scores_gemma":[0.0032943427,0.0011374445,0.00045769723,0.0010664036,0.0001556594,0.00011394339,0.9936328,0.000021222168,0.00012048401],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99395066,0.0023709296,0.0018823369,0.00058634306,0.00093638856,0.00027330997],"domain_scores_gemma":[0.9933742,0.0004073386,0.0023637887,0.0006989824,0.0028068891,0.0003487672],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0031016448,0.00045308427,0.001152842,0.00047241763,0.0001476164,0.000032888514,0.0009261983,0.0012653061,0.0010366194],"category_scores_gemma":[0.005039948,0.00030320094,0.000513476,0.0017023451,0.00070140464,0.00038225262,0.00039415745,0.0008566904,0.000005770064],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000082998835,0.001036905,0.00012613203,0.0035347894,0.0003862595,3.1065437e-7,0.00011226239,8.580837e-7,0.00033779992,0.00021353728,0.9847968,0.0093712965],"study_design_scores_gemma":[0.0015909593,0.00028311805,0.005298209,0.004948963,0.00078148505,0.0000195558,0.000039657178,0.000023371838,0.0031361624,0.00018057077,0.9834127,0.00028525016],"about_ca_topic_score_codex":0.000044709795,"about_ca_topic_score_gemma":0.000002432124,"teacher_disagreement_score":0.034527432,"about_ca_system_score_codex":0.00007590284,"about_ca_system_score_gemma":0.0007873941,"threshold_uncertainty_score":0.999942},"labels":[],"label_agreement":null},{"id":"W4242413941","doi":"10.1002/mc.20107","title":"Targeting NAD(P)H:quinone oxidoreductase (NQO1) in pancreatic cancer","year":2005,"lang":"en","type":"article","venue":"Molecular Carcinogenesis","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; National Cancer Institute; Foundation of Hope for Research and Treatment of Mental Illness; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs","keywords":"Pancreatic cancer; Biology; Clonogenic assay; Cancer research; NAD+ kinase; Pancreatic Intraepithelial Neoplasia; Pancreas; Cancer; Cell culture; Cancer cell; Molecular biology; Cell; Endocrinology; Biochemistry; Enzyme","score_opus":0.07324748171060018,"score_gpt":0.395115716120495,"score_spread":0.3218682344098948,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242413941","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98353255,0.012799384,0.00026309246,0.001300104,0.0004590194,0.00032978703,0.00006208184,0.00006294697,0.0011910587],"genre_scores_gemma":[0.9951037,0.00087530573,0.0007547977,0.0024177565,0.00031426328,0.00012720664,0.000038209902,0.000047552927,0.0003211901],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99791527,0.0003673702,0.0003847846,0.0004794666,0.00020349491,0.0006495862],"domain_scores_gemma":[0.9992975,0.00006246459,0.00010861013,0.00022370373,0.000080171376,0.00022756246],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003658565,0.00029888263,0.00034864934,0.00018535274,0.00017242835,0.000024127869,0.00028701077,0.00022215281,0.0011213614],"category_scores_gemma":[0.000042329586,0.00030441914,0.0001462927,0.0003884671,0.00013415537,0.00010361912,0.000107539854,0.0003716556,0.00009976658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012998328,0.00032276878,0.12767263,0.0000493115,0.00017466728,0.0003739832,0.00030208429,0.0046058367,0.85573035,0.00019122026,0.0018325198,0.008614615],"study_design_scores_gemma":[0.0025617287,0.00007781033,0.038130485,0.000048642432,0.0003784728,0.000036192818,0.00022602349,0.0074709863,0.8757222,0.000087492146,0.07446,0.0007999543],"about_ca_topic_score_codex":0.00034327823,"about_ca_topic_score_gemma":0.00008018214,"teacher_disagreement_score":0.08954215,"about_ca_system_score_codex":0.00020459815,"about_ca_system_score_gemma":0.00010314877,"threshold_uncertainty_score":0.9999408},"labels":[],"label_agreement":null},{"id":"W4243529542","doi":"10.1155/2009/154321","title":"Structural analysis of DNA and RNA interactions with antioxidant flavonoids","year":2009,"lang":"en","type":"article","venue":"Spectroscopy An International Journal","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Natural Sciences and Engineering Research Council of Canada; National and Kapodistrian University of Athens; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Agricultural University of Athens; Islamic Azad University","keywords":"Chemistry; DNA; Stereochemistry; Delphinidin; Kaempferol; Antioxidant; Apigenin; Morin; Adduct; RNA; Flavonoid; Biochemistry; Organic chemistry; Cyanidin","score_opus":0.06255516058498257,"score_gpt":0.4490929548708461,"score_spread":0.38653779428586355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4243529542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952401,0.00006655527,0.0007916981,0.0007995681,0.00086973544,0.00005282951,0.000054442895,0.000016919836,0.002108183],"genre_scores_gemma":[0.9975021,0.00020404656,0.0012502163,0.00053021114,0.00038279363,8.546393e-7,0.00002018603,0.0000064470573,0.00010318084],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9990014,0.00011045251,0.00028565343,0.00018333462,0.00022757266,0.00019157516],"domain_scores_gemma":[0.99922293,0.000041774892,0.00024859206,0.00008641043,0.00023733129,0.00016295454],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001899732,0.00014090016,0.00022932925,0.00042397314,0.0001893594,0.00009055017,0.0002720052,0.000055990742,0.0010848669],"category_scores_gemma":[0.000013234771,0.00011132553,0.000110616624,0.00023877442,0.00014322049,0.00043371774,0.00002351555,0.00048712746,0.0000024322683],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001304381,0.00036539402,0.103367046,0.0000029413732,0.0036187,0.00014372157,0.0006832195,0.0006852612,0.8761987,0.0063518416,0.00025328374,0.007025474],"study_design_scores_gemma":[0.0016292488,0.0009084834,0.7977464,0.00002784684,0.0010834978,0.00050633843,0.00028293495,0.00867923,0.18556745,0.0016051143,0.0016862421,0.00027718092],"about_ca_topic_score_codex":0.000012041156,"about_ca_topic_score_gemma":0.000041235162,"teacher_disagreement_score":0.6943794,"about_ca_system_score_codex":0.000074040174,"about_ca_system_score_gemma":0.00004721221,"threshold_uncertainty_score":0.9998283},"labels":[],"label_agreement":null},{"id":"W4254986934","doi":"10.1002/ange.201804351","title":"Total Synthesis Establishes the Biosynthetic Pathway to the Naphterpin and Marinone Natural Products","year":2018,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Australian Research Council; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Biosynthesis; Chemistry; Halogenation; Total synthesis; Stereochemistry; Biomimetic synthesis; Enzyme; Chlorine; Natural product; Biochemistry; Organic chemistry","score_opus":0.06363162501486763,"score_gpt":0.34495923636579795,"score_spread":0.2813276113509303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4254986934","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9737072,0.001232748,0.0000065991194,0.016115943,0.0014494199,0.0004028935,0.00005943569,0.000058427428,0.006967332],"genre_scores_gemma":[0.9931251,0.00011616821,0.00008274571,0.0029383563,0.0010028208,0.000064206826,0.0000055317482,0.000020586296,0.0026444818],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99874777,0.0001509551,0.00017291465,0.00037524654,0.00014313144,0.0004099987],"domain_scores_gemma":[0.9990211,0.00035133492,0.00006876704,0.00032673657,0.00012042694,0.000111626556],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051016407,0.00022059784,0.00018111954,0.000041125113,0.00062242267,0.00009407845,0.00036762955,0.00011072249,0.0003088783],"category_scores_gemma":[0.0002571652,0.00012065825,0.00005896837,0.00027656948,0.0005904746,0.00010141869,0.00027871339,0.00038073515,0.00013106129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003730339,0.00022249889,0.0044465563,0.000060128827,0.00028319284,0.000032418327,0.0019551702,8.3057955e-7,0.90221304,0.00038301994,0.051868994,0.03816114],"study_design_scores_gemma":[0.00017003033,0.000046726924,0.0062615178,0.000016635913,0.00006121005,0.00006276165,0.00017958335,0.000022862905,0.7657385,0.00003998768,0.22724314,0.0001570559],"about_ca_topic_score_codex":0.000035089935,"about_ca_topic_score_gemma":0.000042381827,"teacher_disagreement_score":0.17537415,"about_ca_system_score_codex":0.000029680012,"about_ca_system_score_gemma":0.000040700732,"threshold_uncertainty_score":0.49203005},"labels":[],"label_agreement":null},{"id":"W4255827122","doi":"10.1107/s1744309105001545","title":"MdaB from<i>Escherichia coli</i>: cloning, purification, crystallization and preliminary X-ray analysis","year":2005,"lang":"en","type":"article","venue":"Acta Crystallographica Section F Structural Biology and Crystallization Communications","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute; Queen's University","funders":"","keywords":"Escherichia coli; Crystallization; Molecular biology; Triclinic crystal system; Gene; Cloning (programming); Chemistry; Biology; Crystallography; Biochemistry; Crystal structure","score_opus":0.04772748760167069,"score_gpt":0.3605904785906872,"score_spread":0.31286299098901654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4255827122","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9746994,0.0029273992,0.015723065,0.004425735,0.0002905936,0.000573573,0.00028676967,0.00025972468,0.0008137899],"genre_scores_gemma":[0.9838031,0.0065848,0.0055658207,0.0010758007,0.00020913436,0.00009834679,0.002481362,0.000029639436,0.0001519864],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9972542,0.0008754002,0.00067197374,0.0006789816,0.00013410792,0.00038532456],"domain_scores_gemma":[0.9977849,0.0004351206,0.0004624309,0.00072653574,0.00033233056,0.00025865415],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0003783157,0.0003882832,0.00042962912,0.00049745466,0.0016603856,0.0001271924,0.0005219861,0.00063095614,0.00060466037],"category_scores_gemma":[0.00009357245,0.00038178888,0.00015230598,0.0012605132,0.0010936161,0.0005225285,0.0003182947,0.0006752903,0.0000013544253],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036670573,0.00030793223,0.22860368,0.000037877027,0.0022325702,0.000001328679,0.0016088171,0.0009186352,0.74884576,0.011608342,0.00076387293,0.004704491],"study_design_scores_gemma":[0.0017372635,0.0002983348,0.5083167,0.000021423368,0.0018082801,0.000016860304,0.0006539003,0.045609087,0.000648564,0.003671307,0.43635923,0.0008590295],"about_ca_topic_score_codex":0.00013617492,"about_ca_topic_score_gemma":0.00044874538,"teacher_disagreement_score":0.7481972,"about_ca_system_score_codex":0.00005868946,"about_ca_system_score_gemma":0.00004703292,"threshold_uncertainty_score":0.9998634},"labels":[],"label_agreement":null},{"id":"W4283271888","doi":"10.5539/ijc.v14n2p1","title":"Synthesis of Analogues of Natural Product ‘Antheminone A’ and Evaluation of Their Anti-Cancer Activity","year":2022,"lang":"en","type":"article","venue":"International Journal of Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Tertiary Education Trust Fund","keywords":"Chemistry; Dicoumarol; Coumarin; Natural product; Combinatorial chemistry; Yield (engineering); Benzaldehyde; Stereochemistry; Cancer cell lines; Cancer cell; Cancer; Organic chemistry","score_opus":0.11768427624280996,"score_gpt":0.44349416030443173,"score_spread":0.32580988406162176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283271888","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99689627,0.0015786359,0.0000035242952,0.00036036526,0.00046947238,0.00004859591,0.0002198419,0.0000015852806,0.00042173598],"genre_scores_gemma":[0.999399,0.00035769443,0.000026765647,0.00002031919,0.00013988517,0.0000045669826,0.0000049432156,0.000004824501,0.000042019416],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989137,0.0001368333,0.0003252819,0.00009126457,0.00046467938,0.00006821008],"domain_scores_gemma":[0.99811846,0.00017628985,0.00083679525,0.000058088568,0.0007804964,0.000029853763],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00092027575,0.000078704106,0.00023286752,0.000062262035,0.000034316716,0.0000030917647,0.0002663555,0.000035239445,0.0007130647],"category_scores_gemma":[0.00012678083,0.00006799568,0.000101003345,0.00006727388,0.00016727124,0.0000781354,0.00009728954,0.0002910773,6.213964e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044896026,0.00042372206,0.02292425,0.000063681495,0.0006472633,0.000003655221,0.00014356893,0.00029254498,0.9534808,0.000005823108,0.00020630713,0.021359427],"study_design_scores_gemma":[0.0006616242,0.000026079373,0.017635435,0.000040309405,0.0001494123,0.00006118921,0.00015794697,0.0008578318,0.97983956,0.00007273619,0.0004436129,0.000054279386],"about_ca_topic_score_codex":0.000008732977,"about_ca_topic_score_gemma":5.007278e-7,"teacher_disagreement_score":0.026358746,"about_ca_system_score_codex":0.000066840854,"about_ca_system_score_gemma":0.00014029689,"threshold_uncertainty_score":0.7807558},"labels":[],"label_agreement":null},{"id":"W4296900401","doi":"10.1002/cmdc.202200310","title":"Optimization of <i>N</i> ‐Piperidinyl‐Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8‐Oxo‐Guanine DNA Glycosylase 1","year":2022,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"HORIZON EUROPE European Research Council; Innovative Medicines Initiative; Dr Åke Olssons Stiftelse för Haematologisk Forskning; Vetenskapsrådet; Crafoordska Stiftelsen; Uppsala Universitet; Cancerfonden; European Federation of Pharmaceutical Industries and Associations; Alfred Österlunds Stiftelse; European Commission; Pain Relief Foundation; Diamond Light Source; McGill University; Karolinska Institutet; Torsten Söderbergs Stiftelse","keywords":"Guanine; DNA glycosylase; Chemistry; DNA; Linker; DNA repair; Base excision repair; Small molecule; DNA damage; Deoxyguanosine; Enzyme; Biochemistry; Stereochemistry; Gene; Nucleotide","score_opus":0.060916680260786706,"score_gpt":0.36200038001530555,"score_spread":0.3010836997545188,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4296900401","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952749,0.00066504866,0.00024099379,0.00042475836,0.00032843807,0.00029939812,0.00011059671,0.000032213713,0.002623643],"genre_scores_gemma":[0.99845463,0.00022950594,0.00051493186,0.00039109873,0.00006850498,0.000048802518,0.000059233116,0.000023943763,0.00020935107],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986924,0.00018053125,0.00036121256,0.000306204,0.00020635968,0.00025330635],"domain_scores_gemma":[0.9991212,0.00015372252,0.0003248165,0.00013070046,0.00014537631,0.00012421203],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031055557,0.00019947572,0.00034393198,0.00010768475,0.00023753016,0.000005705766,0.00017323525,0.000111670066,0.00072021125],"category_scores_gemma":[0.00008154723,0.00020705679,0.000088164634,0.00038321887,0.0003473976,0.00009033847,0.00027215545,0.00039764112,0.0000021352453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010204177,0.001183109,0.008186236,0.00015438866,0.00033572133,0.000026921844,0.002219472,0.0044500604,0.97507155,0.0006669746,0.0036700906,0.0030150414],"study_design_scores_gemma":[0.0015299005,0.00035518114,0.00080374593,0.000013110068,0.00008881159,0.000036473593,0.00081764755,0.002595805,0.9902977,0.00018670583,0.0030807469,0.00019420555],"about_ca_topic_score_codex":0.000020418807,"about_ca_topic_score_gemma":0.0000013868924,"teacher_disagreement_score":0.0152261,"about_ca_system_score_codex":0.00007875387,"about_ca_system_score_gemma":0.00008940845,"threshold_uncertainty_score":0.844353},"labels":[],"label_agreement":null},{"id":"W4308435289","doi":"10.1680/jbibn.21.00053","title":"Apoptosis-based topotecan-loaded superparamagnetic drug delivery system: an in vitro study","year":2022,"lang":"en","type":"article","venue":"Bioinspired Biomimetic and Nanobiomaterials","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Topotecan; Apoptosis; Cytotoxicity; Annexin; Propidium iodide; Drug delivery; Materials science; Superparamagnetism; Cancer research; Nanobiotechnology; Nanoparticle; Chemistry; Nanotechnology; In vitro; Medicine; Programmed cell death; Biochemistry","score_opus":0.06940324159676532,"score_gpt":0.3538205770857067,"score_spread":0.2844173354889414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308435289","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99547756,0.00035376032,0.0000023141322,0.00015024922,0.001919249,0.0014059226,0.00039860606,0.00017085965,0.000121453304],"genre_scores_gemma":[0.99872464,0.000013404678,0.00012488509,0.00044345224,0.000100615915,0.00030400793,0.00018199279,0.000040209783,0.00006679968],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9957924,0.0019368633,0.000669346,0.0007069411,0.0002584988,0.0006359638],"domain_scores_gemma":[0.9990313,0.00011980468,0.00019506738,0.00032325604,0.00006091769,0.0002696225],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013874471,0.00038731087,0.0006166736,0.00042762412,0.0007115036,0.000096115305,0.0004321651,0.0001567345,0.0005171283],"category_scores_gemma":[0.000014712046,0.0003775051,0.00009240565,0.0004681622,0.00024182053,0.000116447845,0.00027564954,0.00019745644,0.000027530814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019468577,0.002537858,0.013188783,0.000097232274,0.00006761528,0.00005968754,0.0003939757,0.0000052041164,0.97925156,0.00001789873,0.00018187599,0.0022514432],"study_design_scores_gemma":[0.00760369,0.0011046461,0.018750904,0.000015854017,0.00020555353,0.000012923282,0.0020365424,0.00075883575,0.96664417,0.000010587536,0.0022900673,0.00056622975],"about_ca_topic_score_codex":0.00047094832,"about_ca_topic_score_gemma":0.000011596064,"teacher_disagreement_score":0.012607402,"about_ca_system_score_codex":0.00021232835,"about_ca_system_score_gemma":0.00011843484,"threshold_uncertainty_score":0.9998677},"labels":[],"label_agreement":null},{"id":"W4327606736","doi":"10.1016/j.eclinm.2023.101897","title":"Napabucasin plus nab-paclitaxel with gemcitabine versus nab-paclitaxel with gemcitabine in previously untreated metastatic pancreatic adenocarcinoma: an adaptive multicentre, randomised, open-label, phase 3, superiority trial","year":2023,"lang":"en","type":"article","venue":"EClinicalMedicine","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Gemcitabine; Hazard ratio; Nab-paclitaxel; Internal medicine; Pancreatic cancer; Oncology; Clinical endpoint; Adenocarcinoma; Gastroenterology; Confidence interval; Cancer; Clinical trial","score_opus":0.38663698791539697,"score_gpt":0.5231980314798126,"score_spread":0.13656104356441562,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4327606736","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98560697,0.0015979273,0.00012566373,0.0016595622,0.0015776623,0.00764781,0.00033482822,0.00029583904,0.0011537168],"genre_scores_gemma":[0.99306834,0.0009280046,0.0014027423,0.00095853844,0.0007478513,0.00080200395,0.00073876145,0.00014578411,0.0012079581],"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","domain_scores_codex":[0.99137264,0.0026056739,0.0019119338,0.0016669208,0.0007670134,0.001675819],"domain_scores_gemma":[0.9922812,0.004469293,0.00070533267,0.00093935407,0.0004270264,0.0011777682],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0039782478,0.0010455879,0.0026188558,0.00047938997,0.0005229041,0.00011808267,0.0010965127,0.00044965406,0.0012590269],"category_scores_gemma":[0.0015799353,0.00075063924,0.00017439731,0.0019634473,0.0013697589,0.0006801926,0.00036730178,0.0019539192,0.00020726636],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.95665765,0.010992677,0.017107004,0.00022811211,0.0023127238,0.0041832966,0.0019458899,0.0001337863,0.00069290237,0.000235071,0.0017326841,0.0037781945],"study_design_scores_gemma":[0.92219067,0.041192845,0.0091434335,0.0004388755,0.003096746,0.00009803833,0.002841984,0.016243909,0.0002191164,0.00009591656,0.003382073,0.0010564073],"about_ca_topic_score_codex":0.00080481113,"about_ca_topic_score_gemma":0.0012807325,"teacher_disagreement_score":0.034467,"about_ca_system_score_codex":0.00041496425,"about_ca_system_score_gemma":0.0009468113,"threshold_uncertainty_score":0.99965394},"labels":[],"label_agreement":null},{"id":"W4361191279","doi":"10.1128/aac.01600-22","title":"The Natural Stilbenoid (–)-Hopeaphenol Inhibits HIV Transcription by Targeting Both PKC and NF-κB Signaling and Cyclin-Dependent Kinase 9","year":2023,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"National Institute of Allergy and Infectious Diseases; Alliance for Accelerating Excellence in Science in Africa; African Academy of Sciences; Ben Franklin Technology Partners of Northeastern Pennsylvania; Canadian Institutes of Health Research; Department of Education and Training; Simon Fraser University; Wellcome Trust; Griffith University; New Partnership for Africa's Development; Australian Research Council; Pennsylvania Department of Community and Economic Development; Fred J. Brotherton Charitable Foundation; Christian R. and Mary F. Lindback Foundation","keywords":"Kinase; Protein kinase C; Signal transduction; Human immunodeficiency virus (HIV); Transcription (linguistics); Transcription factor; Cancer research; Biology; Chemistry; Virology; Cell biology; Biochemistry; Gene","score_opus":0.03870535954623209,"score_gpt":0.3399781606213086,"score_spread":0.3012728010750765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4361191279","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928969,0.0012560048,0.000038238217,0.0045629977,0.0005963735,0.00034740818,0.00010281742,0.00008542664,0.00011383888],"genre_scores_gemma":[0.9793178,0.013609305,0.000052137195,0.005411016,0.00019000364,0.000008873347,0.00007421206,0.000038312915,0.0012983835],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984961,0.00015838692,0.0003013772,0.00044045132,0.00012236202,0.00048132613],"domain_scores_gemma":[0.99948543,0.000114308605,0.00011735673,0.00009294463,0.00003953547,0.00015044482],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047107693,0.00028717204,0.00024291624,0.00006001984,0.0010131797,0.00017374632,0.00013943897,0.00016993887,0.00008039033],"category_scores_gemma":[0.000010042063,0.00022124691,0.00006202951,0.0001426539,0.00030496606,0.00014907346,0.000076245924,0.00043158513,0.000012697735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031611614,0.00011558825,0.009831036,0.000059880007,0.00017010917,0.000021710457,0.0010642592,0.0000065044915,0.91446054,0.00006182743,0.05366841,0.020224012],"study_design_scores_gemma":[0.007955624,0.00018737544,0.013790705,0.000111847825,0.00017355943,0.000056006,0.0010232248,0.0036802178,0.5578003,0.00025798785,0.41399714,0.00096602587],"about_ca_topic_score_codex":0.000026803698,"about_ca_topic_score_gemma":0.000009450156,"teacher_disagreement_score":0.36032873,"about_ca_system_score_codex":0.000019067897,"about_ca_system_score_gemma":0.000016622209,"threshold_uncertainty_score":0.90221876},"labels":[],"label_agreement":null},{"id":"W4366495377","doi":"10.15562/phytomedicine.2022.188","title":"Phytochemical Screening and in vitro Antimicrobial Activity of Lawsonia Inermis Barks","year":2023,"lang":"en","type":"article","venue":"Discovery Phytomedicine - Journal of Natural Products Research and Ethnopharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Lawsonia inermis; Phytochemical; Antimicrobial; Traditional medicine; Agar diffusion test; Antibacterial activity; Punica; Biology; Chemistry; Microbiology; Medicine; Bacteria","score_opus":0.18380572484856197,"score_gpt":0.4914603386590012,"score_spread":0.30765461381043924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366495377","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98724616,0.0035332923,0.0000054818256,0.0077022035,0.001057584,0.00032327793,0.000039879855,0.000012817112,0.00007931908],"genre_scores_gemma":[0.9944253,0.0040647686,0.000094183124,0.00031465414,0.0008009104,0.0000056952285,0.000013408163,0.000019247484,0.00026183334],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972431,0.00068617176,0.0005419613,0.0003877581,0.00042435716,0.000716619],"domain_scores_gemma":[0.99799776,0.00087733095,0.0002795763,0.00011522842,0.0004967039,0.00023339051],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0028254702,0.00022969361,0.00067210465,0.00087789446,0.0001758664,0.000025414714,0.00030385275,0.00022343456,0.000028329838],"category_scores_gemma":[0.0005661188,0.00018067239,0.00006943221,0.0012964216,0.0014915217,0.00049971626,0.00033874845,0.0028141297,0.0000022867457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0078004,0.0003413454,0.004228735,0.00033456742,0.00019390561,0.00043980623,0.0002739135,0.000015955275,0.9638615,0.0000070213864,0.009946489,0.012556335],"study_design_scores_gemma":[0.0053412654,0.0005568217,0.036024414,0.00012955164,0.000061957224,0.00018757685,0.0001717236,0.00075128785,0.95334464,0.00013475236,0.0031141732,0.00018182509],"about_ca_topic_score_codex":0.000026017571,"about_ca_topic_score_gemma":0.0000037390191,"teacher_disagreement_score":0.03179568,"about_ca_system_score_codex":0.000055929762,"about_ca_system_score_gemma":0.00018512455,"threshold_uncertainty_score":0.99948645},"labels":[],"label_agreement":null},{"id":"W4378363830","doi":"10.1021/acs.jmedchem.3c00398","title":"Investigation into the Mechanism of Action of the Tuberculosis Drug Candidate SQ109 and Its Metabolites and Analogues in Mycobacteria","year":2023,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; University of Illinois at Urbana-Champaign; National Institutes of Health; Science Foundation Ireland","keywords":"Mycobacterium smegmatis; Mycobacterium tuberculosis; Chemistry; Mechanism of action; Growth inhibition; Metabolite; Biochemistry; Phosphatase; Mycobacterium; Bedaquiline; Enzyme; Cell growth; IC50; Biosynthesis; Tuberculosis; Bacteria; Microbiology; In vitro; Biology; Genetics","score_opus":0.07899831562065666,"score_gpt":0.3789371423686985,"score_spread":0.29993882674804184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378363830","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958271,0.0015919222,0.0000010444318,0.0021880413,0.0002782323,0.000053667663,0.000009910777,0.0000024281287,0.000047697427],"genre_scores_gemma":[0.99666893,0.002992536,0.000009905638,0.0001320574,0.00012637807,0.000001478159,0.0000027599433,0.000004074919,0.00006186184],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99920636,0.00014995736,0.00031768077,0.0000741259,0.00015858258,0.00009329453],"domain_scores_gemma":[0.9992562,0.00017087157,0.0003552685,0.00005376617,0.00009850162,0.00006536881],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009261061,0.00008117771,0.00020316147,0.000049033355,0.000067640474,0.0000049969162,0.00012412957,0.00007812188,0.00003636377],"category_scores_gemma":[0.00011810245,0.000046480352,0.000042536016,0.0002061527,0.0001947525,0.00007125606,0.000056444453,0.00036751025,2.1847839e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009114874,0.000017974682,0.028820632,0.00020054729,0.00009143594,0.000005656561,0.0018356743,0.0000034012976,0.9677678,0.000073811425,0.00023888088,0.0008530435],"study_design_scores_gemma":[0.00061513577,0.000027534275,0.06533737,0.00012473983,0.00016627758,0.0000541413,0.0014584535,0.0003498812,0.9298927,0.0014686865,0.00046151225,0.00004353111],"about_ca_topic_score_codex":0.000049515984,"about_ca_topic_score_gemma":0.00002352695,"teacher_disagreement_score":0.037875056,"about_ca_system_score_codex":0.000019020843,"about_ca_system_score_gemma":0.00006228408,"threshold_uncertainty_score":0.18954137},"labels":[],"label_agreement":null},{"id":"W4379093502","doi":"10.1021/jacs.3c00398","title":"Photo-Uncaging by C(sp<sup>3</sup>)–C(sp<sup>3</sup>) Bond Cleavage Restores β-Lapachone Activity","year":2023,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Division of Chemistry; Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"Chemistry; Bond cleavage; Cleavage (geology); Stereochemistry; Photochemistry; Organic chemistry; Catalysis","score_opus":0.06212315857110225,"score_gpt":0.37927008242545396,"score_spread":0.3171469238543517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4379093502","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917126,0.00030446218,0.00006217895,0.0061933575,0.00043743296,0.00021885995,0.00013926906,0.00009836702,0.0008334162],"genre_scores_gemma":[0.9920722,0.0008653852,0.00031126966,0.00502454,0.00094168476,0.000010970758,0.000011127462,0.0000656491,0.00069713854],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99681336,0.00048349742,0.0006475027,0.00045517134,0.00068138685,0.00091908744],"domain_scores_gemma":[0.99723816,0.0007342192,0.0010022592,0.00039651777,0.00015606981,0.00047276306],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0012417273,0.00045365715,0.0008419324,0.00006712042,0.00059165875,0.0000779591,0.0011065339,0.00028238323,0.00020808482],"category_scores_gemma":[0.00020921443,0.000336647,0.0011165291,0.00096943113,0.0014821838,0.0002674742,0.00049865135,0.0027000953,0.00007115812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035661078,0.0003719885,0.012785439,0.000031837328,0.00051516504,0.000030419737,0.0010460078,0.00024245882,0.5175952,0.0000058621686,0.46363536,0.0033836917],"study_design_scores_gemma":[0.0030241476,0.00030081128,0.008488587,0.00009584023,0.00054051785,0.00019145427,0.0029174583,0.01224559,0.7324305,0.00033626935,0.23861797,0.0008108242],"about_ca_topic_score_codex":0.00008331429,"about_ca_topic_score_gemma":7.2425416e-7,"teacher_disagreement_score":0.22501738,"about_ca_system_score_codex":0.00041028322,"about_ca_system_score_gemma":0.00016272995,"threshold_uncertainty_score":0.99990857},"labels":[],"label_agreement":null},{"id":"W4381470472","doi":"10.1080/14786419.2023.2225121","title":"Perezone and its phenyl glycine derivative induce cytotoxicity via caspases on human glial cancer cells","year":2023,"lang":"en","type":"article","venue":"Natural Product Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Cytotoxic T cell; Cytotoxicity; Apoptosis; Vacuolization; Chemistry; Glycine; Cell culture; IC50; Caspase 3; Stereochemistry; Molecular biology; Biochemistry; Pharmacology; In vitro; Programmed cell death; Biology; Amino acid; Endocrinology","score_opus":0.4655901654840231,"score_gpt":0.5737525384239427,"score_spread":0.1081623729399196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381470472","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99092877,0.0018502374,4.1822963e-7,0.0043815,0.0010713608,0.00085892976,0.000107609434,0.000113687325,0.00068751664],"genre_scores_gemma":[0.99143255,0.00078322017,0.000009577485,0.00040236223,0.0013145788,0.00009105747,0.00004129028,0.0000319101,0.0058934367],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99675083,0.00081130373,0.00023516259,0.0007569181,0.0005642434,0.0008815165],"domain_scores_gemma":[0.9985585,0.00041291298,0.000070200425,0.00021951598,0.0004970326,0.00024180542],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0013799837,0.000265027,0.0002961892,0.00032721515,0.0011246009,0.000055913762,0.0003539231,0.0002081083,0.0006939757],"category_scores_gemma":[0.00026354613,0.00021741711,0.000058712285,0.0010222151,0.00044929498,0.00016566971,0.00036538122,0.0025087332,0.00025739652],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005535945,0.00025509504,0.0017879251,0.00010148843,0.00012006703,0.00012518444,0.0004861008,0.000017426004,0.9716617,0.00030285862,0.017883655,0.0067048958],"study_design_scores_gemma":[0.0010873695,0.00035288418,0.023815803,0.000043165986,0.000022150289,0.00001010219,0.000120152086,0.00072052836,0.96229684,0.00025340868,0.010997199,0.00028039774],"about_ca_topic_score_codex":0.00022009651,"about_ca_topic_score_gemma":0.00010344651,"teacher_disagreement_score":0.022027878,"about_ca_system_score_codex":0.00016867147,"about_ca_system_score_gemma":0.00010555164,"threshold_uncertainty_score":0.9997925},"labels":[],"label_agreement":null},{"id":"W4383197651","doi":"10.1016/j.sciaf.2023.e01795","title":"Inhibition characteristics of peptide extracts of four medicinal plants on activities of bovine trypsin","year":2023,"lang":"en","type":"article","venue":"Scientific African","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fonds de recherche du Québec; Department for International Development, UK Government; International Development Research Centre; National Research Foundation; Newton Fund; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Trypsin; Momordica; Proteases; Protease; Peptide; Chemistry; Medicinal plants; Biochemistry; IC50; Traditional medicine; Biology; Enzyme; In vitro; Medicine","score_opus":0.15139738524866095,"score_gpt":0.393780582513522,"score_spread":0.24238319726486104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383197651","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921096,0.000023077762,0.000016706874,0.00015785787,0.0014937385,0.00015375395,0.00081646163,0.000028038039,0.0052007805],"genre_scores_gemma":[0.9975221,0.000028126988,0.00003359379,0.0000338386,0.00008092368,0.0000054887896,0.00010590129,0.000010967835,0.0021790224],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985473,0.00016128014,0.0004184123,0.00024734507,0.00035537322,0.00027028605],"domain_scores_gemma":[0.99887514,0.00027935466,0.00044473508,0.00018532624,0.00011458811,0.00010084771],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00085343624,0.00013365927,0.00033356022,0.00035409082,0.00013286466,0.000009045455,0.00017173118,0.0001002606,0.00042252487],"category_scores_gemma":[0.000099796416,0.00011998349,0.00008879403,0.0005208622,0.000846627,0.00007536889,0.00006659734,0.0002297489,0.00002406235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008356547,0.0007142474,0.009342562,0.0002605477,0.00010925398,0.000058923175,0.0026171554,0.000019773375,0.9570414,0.000686513,0.014474662,0.013839317],"study_design_scores_gemma":[0.0012541756,0.0006736559,0.12072056,0.00022790344,0.00009870628,0.000013968676,0.002564581,0.00064246124,0.8574198,0.00038248493,0.015771879,0.00022984498],"about_ca_topic_score_codex":0.00001267368,"about_ca_topic_score_gemma":0.000010084867,"teacher_disagreement_score":0.111378,"about_ca_system_score_codex":0.000026548301,"about_ca_system_score_gemma":0.000094344054,"threshold_uncertainty_score":0.48927847},"labels":[],"label_agreement":null},{"id":"W4384563170","doi":"10.1016/j.ejps.2023.106529","title":"Design, synthesis and biological evaluation of a novel bioactive indane scaffold 2-(diphenylmethylene)c-2,3-dihydro-1H-inden-1-one with potential anticancer activity","year":2023,"lang":"en","type":"article","venue":"European Journal of Pharmaceutical Sciences","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"Trinity College Dublin","keywords":"Chemistry; Cytotoxicity; SKBR3; A549 cell; Stereochemistry; DU145; Moiety; In vitro; Biochemistry; Cancer cell; Biology; Cancer","score_opus":0.4405693627650637,"score_gpt":0.46893937971205785,"score_spread":0.028370016946994148,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384563170","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893825,0.00043861527,0.0071290815,0.0011744793,0.0004800637,0.00032040777,0.00003243666,0.000031074123,0.0010113373],"genre_scores_gemma":[0.9967304,0.0008653797,0.0019416698,0.00018356749,0.00023784513,0.00000524453,7.0517905e-7,0.000017873337,0.000017345008],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99456364,0.0030306817,0.00050652464,0.00040711946,0.000986416,0.00050561223],"domain_scores_gemma":[0.99755955,0.00096851087,0.00055811036,0.00010141856,0.00045025986,0.00036214094],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.011904911,0.0002582043,0.0004564299,0.00032723072,0.00038584467,0.000060482605,0.0004939003,0.00009208976,0.00045631576],"category_scores_gemma":[0.0004213368,0.00017691376,0.000115546485,0.0009419236,0.0020457406,0.0003583012,0.0001870564,0.0005881089,0.000016215665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018631499,0.0011435921,0.0068987645,0.0000447856,0.0005301281,0.00015225568,0.00032696486,0.0029982459,0.8683164,0.0001111803,0.00015810801,0.11745642],"study_design_scores_gemma":[0.0074988455,0.0026189513,0.12640071,0.000255932,0.0013900005,0.00039097646,0.00059417513,0.0929628,0.764989,0.00020578719,0.0020366968,0.00065611006],"about_ca_topic_score_codex":0.0000039136594,"about_ca_topic_score_gemma":7.5222385e-7,"teacher_disagreement_score":0.11950195,"about_ca_system_score_codex":0.00006423901,"about_ca_system_score_gemma":0.00022965469,"threshold_uncertainty_score":0.7537616},"labels":[],"label_agreement":null},{"id":"W4385284415","doi":"10.33393/dti.2009.1337","title":"A Model for NAD(P)H:Quinoneoxidoreductase 1 (NQO1) Targeted Individualized Cancer Chemotherapy","year":2009,"lang":"en","type":"article","venue":"Drug Target Insights","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"CancerCare Manitoba Foundation; Welch Foundation","keywords":"Medicine; Chemotherapy; Cancer imaging; Cancer chemotherapy; Oncology; NAD+ kinase; Cancer; Internal medicine; Medical physics; Bioinformatics; Cancer research; Biology; Biochemistry; Enzyme","score_opus":0.1214002722564105,"score_gpt":0.42995407238189937,"score_spread":0.3085538001254889,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385284415","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98014885,0.0041780397,0.0028094049,0.0052074725,0.0017908314,0.0014689359,0.00076971314,0.00030019053,0.003326551],"genre_scores_gemma":[0.97449815,0.00055903,0.0063874186,0.013555121,0.0005819,0.00020556175,0.0003047749,0.00005092825,0.0038571227],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978075,0.00018163008,0.0004487222,0.00060714275,0.00023558139,0.00071939186],"domain_scores_gemma":[0.99883693,0.000113111346,0.00022344143,0.00027735706,0.00019986209,0.00034926843],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00029160135,0.00044260177,0.0005035236,0.00018401326,0.00052464043,0.000051940395,0.00045511755,0.00031837722,0.00096213794],"category_scores_gemma":[0.00002788883,0.0003903439,0.00025734794,0.00028154385,0.00016066438,0.00024737077,0.000040527775,0.00050111243,0.00004061553],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004261055,0.0041894745,0.0024274478,0.00016462644,0.001290389,0.0001049806,0.01920116,0.0063560726,0.4458682,0.016568411,0.47053313,0.029035047],"study_design_scores_gemma":[0.008864115,0.00019274857,0.0012665788,0.000035020257,0.00020689462,0.000010435591,0.00015147886,0.19827226,0.22022432,0.025129529,0.54460883,0.0010378064],"about_ca_topic_score_codex":0.000022881868,"about_ca_topic_score_gemma":0.000024645567,"teacher_disagreement_score":0.22564387,"about_ca_system_score_codex":0.0001137743,"about_ca_system_score_gemma":0.0002103738,"threshold_uncertainty_score":0.9999511},"labels":[],"label_agreement":null},{"id":"W4385722997","doi":"10.2174/9789815124330123010003","title":"Chromene and its Importance: Chemistry and Biology","year":2023,"lang":"en","type":"book-chapter","venue":"BENTHAM SCIENCE PUBLISHERS eBooks","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Antifungal; Antimicrobial; Chemistry; Benzopyrans; Pharmacology; Human immunodeficiency virus (HIV); Biology; Organic chemistry; Microbiology","score_opus":0.1904110034681234,"score_gpt":0.4121279527822653,"score_spread":0.22171694931414193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385722997","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.077068575,0.0012522985,0.0000015015688,0.00048185443,0.0015490175,0.0004363145,0.00017001273,0.00017242465,0.918868],"genre_scores_gemma":[0.31802738,0.0004110999,0.000036758676,0.00080423325,0.00038642742,0.000036913043,0.000057020512,0.00007054141,0.68016964],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99762446,0.000027479033,0.0003683794,0.001042321,0.00024751568,0.00068987353],"domain_scores_gemma":[0.99860406,0.000107622756,0.0002883957,0.00026393528,0.00019187844,0.00054411375],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009884022,0.00043788337,0.00043963536,0.0001896605,0.00060748437,0.00034129742,0.00060014083,0.0006651871,0.00096076145],"category_scores_gemma":[0.00008436778,0.00041467935,0.00007851685,0.00008456669,0.00246327,0.00037318995,0.0006519326,0.000943278,0.000041441748],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035324818,0.00023469908,0.017990995,0.001327796,0.0013062408,0.00058887823,0.001835521,0.00000285858,0.42185244,0.32999295,0.08016744,0.14434694],"study_design_scores_gemma":[0.0016255148,0.00017904594,0.002190738,0.00011956682,0.00023782458,0.0001551629,0.00016591883,0.00039404008,0.009310052,0.019565966,0.96466905,0.0013871393],"about_ca_topic_score_codex":0.0000053194676,"about_ca_topic_score_gemma":0.000006987995,"teacher_disagreement_score":0.8845016,"about_ca_system_score_codex":0.00010796335,"about_ca_system_score_gemma":0.00033699966,"threshold_uncertainty_score":0.9999525},"labels":[],"label_agreement":null},{"id":"W4387603459","doi":"10.3389/fphar.2023.1279215","title":"Evaluation of anti-inflammatory and immunomodulatory potential of Lawsone (2-hydroxy-1,4-naphthoquinone) using pre-clinical rodent model of rheumatoid arthritis","year":2023,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"King Saud University","keywords":"Lawsone; Pharmacology; Naphthoquinone; Juglone; Inflammation; Chemistry; Rheumatoid arthritis; Medicine; Immunology; Biochemistry; Pathology","score_opus":0.13719765509608806,"score_gpt":0.43679129729821137,"score_spread":0.2995936422021233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387603459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98938376,0.004292534,0.0013321867,0.000051772244,0.0040251208,0.00066942436,0.000115074065,0.000030329358,0.00009979785],"genre_scores_gemma":[0.98699456,0.0116492035,0.0011050641,0.000063233594,0.00008244373,0.000028303875,0.000021203308,0.000029954796,0.000026028592],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99590343,0.0015074108,0.0012833286,0.00042991037,0.00044577464,0.00043014818],"domain_scores_gemma":[0.9984407,0.0001412694,0.0007090389,0.0001965204,0.0003847727,0.00012770644],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0046856604,0.0002464508,0.00086855225,0.00050416106,0.00009156095,0.000004105458,0.0002896414,0.00041441442,0.00013846585],"category_scores_gemma":[0.000074944015,0.00027696518,0.00018375512,0.00036190174,0.0009991315,0.00016356901,0.00022684326,0.00051882694,0.0000030599701],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071403274,0.00075277884,0.19024834,0.00015214938,0.0007108979,0.000024271276,0.0005103674,0.08648101,0.7027894,0.000056387573,0.003214,0.014346344],"study_design_scores_gemma":[0.0066588465,0.00015764682,0.08828177,0.00007224386,0.00030912674,0.000015228738,0.00017927655,0.8190117,0.08401641,0.000763096,0.00030020453,0.00023445442],"about_ca_topic_score_codex":0.00003309401,"about_ca_topic_score_gemma":0.0000046928863,"teacher_disagreement_score":0.73253065,"about_ca_system_score_codex":0.00009129925,"about_ca_system_score_gemma":0.0003574788,"threshold_uncertainty_score":0.99996823},"labels":[],"label_agreement":null},{"id":"W4389572256","doi":"10.3389/fntpr.2023.1281061","title":"Curcuphenols facilitate the immune driven attenuation of metastatic tumour growth","year":2023,"lang":"en","type":"article","venue":"Frontiers in Natural Products","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Coastal Health","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Urology Foundation","keywords":"Immune system; Immunotherapy; Context (archaeology); Cancer immunotherapy; Biology; Immunology; Antigen; Cancer; Human leukocyte antigen; Cancer research; Genetics","score_opus":0.10987707827039558,"score_gpt":0.3741586644029157,"score_spread":0.26428158613252006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389572256","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9828908,0.004239785,0.00007966904,0.0059671234,0.0056109102,0.00072071224,0.00006713945,0.00007393859,0.0003499273],"genre_scores_gemma":[0.99692225,0.0003351644,0.00063754537,0.00016411679,0.00010689918,0.00002879187,0.00007254505,0.000014655389,0.0017180012],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983257,0.0004530748,0.0003573144,0.00030655754,0.00019401248,0.00036334537],"domain_scores_gemma":[0.99931836,0.0001298994,0.00016936261,0.0001733617,0.00017118052,0.000037862395],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008647282,0.00017292974,0.0002915023,0.0001899355,0.0001592493,0.000013188953,0.0003678624,0.00007047168,0.00002692203],"category_scores_gemma":[0.00037090754,0.00012359027,0.00007902251,0.0009851152,0.00029516156,0.00015886423,0.00010446482,0.0006160102,0.00005647161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00086793443,0.0005293771,0.13190745,0.00069592614,0.0009589708,0.00012722172,0.0065690475,0.0009976993,0.56661826,0.0019761086,0.26285535,0.025896687],"study_design_scores_gemma":[0.0050186715,0.0002759832,0.44246215,0.00013722395,0.00040289765,0.000027299197,0.0033850702,0.02617776,0.4661651,0.011709146,0.043243993,0.0009947256],"about_ca_topic_score_codex":0.000033221815,"about_ca_topic_score_gemma":0.000005014853,"teacher_disagreement_score":0.31055468,"about_ca_system_score_codex":0.000057249174,"about_ca_system_score_gemma":0.00005130475,"threshold_uncertainty_score":0.5039865},"labels":[],"label_agreement":null},{"id":"W4391031967","doi":"10.20944/preprints202401.1374.v1","title":"Exploring Solar Drying of Henna (&lt;em&gt;Lawsonia inermis&lt;/em&gt;) and Its Effect on the Bioactivities","year":2024,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick","funders":"","keywords":"Solar dryer; Water content; Food science; Pulp and paper industry; Chemistry; Engineering","score_opus":0.3546685015432753,"score_gpt":0.4223598934258747,"score_spread":0.06769139188259943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391031967","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98423165,0.0027893235,0.000007412317,0.0007739391,0.003933926,0.0013321688,0.00021025201,0.00025073765,0.006470575],"genre_scores_gemma":[0.99461687,0.0026634515,0.000016080638,0.00034655852,0.000588311,0.00054627075,0.000026543554,0.0001158332,0.001080103],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9953631,0.0012394311,0.00075488415,0.0013912441,0.00048712525,0.0007642213],"domain_scores_gemma":[0.99696326,0.0012108363,0.00048262108,0.00090135855,0.00017528818,0.00026661638],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.002564434,0.0008741399,0.0010034202,0.00036236434,0.0004974168,0.00009426804,0.0009374471,0.00067281397,0.00087111787],"category_scores_gemma":[0.00036720975,0.0006967561,0.0004666648,0.00029231093,0.0003953784,0.00018994394,0.0036516192,0.003609959,0.0006451127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011958332,0.0008061832,0.08378434,0.0039349967,0.0033875944,0.00024683838,0.008786298,0.00039961928,0.87928885,0.0059090545,0.00047788487,0.011782489],"study_design_scores_gemma":[0.0010728871,0.00023356688,0.048820373,0.001144795,0.0008477024,0.000034785644,0.00043942017,0.0013988517,0.92418975,0.0016484101,0.019159181,0.0010102541],"about_ca_topic_score_codex":0.000027613352,"about_ca_topic_score_gemma":0.000022023783,"teacher_disagreement_score":0.044900905,"about_ca_system_score_codex":0.00017473857,"about_ca_system_score_gemma":0.00015437888,"threshold_uncertainty_score":0.9995484},"labels":[],"label_agreement":null},{"id":"W4391337939","doi":"10.22541/au.170665207.75493468/v1","title":"Title: Synergic effects of anticancer peptide CIGB-552 and Cisplatin in lung cancer models","year":2024,"lang":"en","type":"preprint","venue":"","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"In vivo; Cisplatin; Combination therapy; Pharmacology; Cancer research; Concomitant; Apoptosis; Lung cancer; Chemotherapy; Chemistry; Medicine; Oncology; Biology; Internal medicine; Biochemistry","score_opus":0.08251194084609488,"score_gpt":0.44734771823531394,"score_spread":0.3648357773892191,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391337939","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83499473,0.026890071,0.00016544409,0.00045649734,0.0038363878,0.0006326423,0.000138477,0.000066792614,0.13281895],"genre_scores_gemma":[0.98778456,0.0049107317,0.00012259171,0.00029188118,0.00014131817,0.00006081817,0.00000899657,0.00002414279,0.0066549657],"study_design_codex":"not_applicable","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9990573,0.00009325417,0.00022460538,0.000326692,0.00009556699,0.0002025927],"domain_scores_gemma":[0.99955493,0.00014106893,0.00007572421,0.00012349538,0.00003447487,0.000070290494],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001605518,0.00019983941,0.00032619195,0.00012624174,0.00002539624,0.000015303987,0.0001312192,0.00033038802,0.0018220696],"category_scores_gemma":[0.000009347719,0.00017285183,0.000072932155,0.00009771958,0.00011773552,0.000023141876,0.0004337953,0.00089973555,0.000025105186],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010601472,0.0018460552,0.076112986,0.055008903,0.005744887,0.0015705808,0.004283132,0.01685476,0.08486874,0.09577965,0.57765895,0.079211235],"study_design_scores_gemma":[0.0027365335,0.00012935333,0.009357204,0.0032911361,0.0015881406,0.000016689592,0.00006771823,0.8507724,0.06437294,0.03686698,0.029291978,0.0015089696],"about_ca_topic_score_codex":0.0001612025,"about_ca_topic_score_gemma":0.000053927164,"teacher_disagreement_score":0.8339176,"about_ca_system_score_codex":0.000061020408,"about_ca_system_score_gemma":0.00011418304,"threshold_uncertainty_score":0.9990904},"labels":[],"label_agreement":null},{"id":"W4392001743","doi":"10.3389/fchem.2024.1351669","title":"Exploring the anticancer and antibacterial potential of naphthoquinone derivatives: a comprehensive computational investigation","year":2024,"lang":"en","type":"article","venue":"Frontiers in Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Alliance de recherche numérique du Canada; North South University","keywords":"In silico; Chemistry; Protein Data Bank (RCSB PDB); Naphthoquinone; Quantitative structure–activity relationship; Stereochemistry; Ligand (biochemistry); Molecular dynamics; Docking (animal); Computational chemistry; Computational biology; Biochemistry; Biology; Organic chemistry","score_opus":0.14678696247259904,"score_gpt":0.37543314926957777,"score_spread":0.22864618679697873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392001743","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951938,0.0012350015,0.001177953,0.00047572068,0.001533681,0.000109986584,0.000048120022,0.000022823348,0.00020295959],"genre_scores_gemma":[0.998015,0.00041702157,0.001138105,0.00012175945,0.00021012106,0.000016265985,0.000031153973,0.000010030631,0.00004053557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992581,0.00008084891,0.0002031351,0.00020702026,0.00010077695,0.0001501244],"domain_scores_gemma":[0.99968874,0.000099823235,0.00005371358,0.00006179496,0.000046092875,0.000049849656],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013439644,0.00011513803,0.00016058623,0.000041444393,0.00008500094,0.000025890004,0.00010179992,0.00009674795,0.00007199348],"category_scores_gemma":[0.000015022365,0.000096097916,0.000040093415,0.0001749465,0.0005185729,0.00014169484,0.000060067377,0.00040411807,0.00000108395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029184663,0.0000923943,0.055853922,0.00071162765,0.00034345296,0.00007040804,0.0019241126,0.00084686006,0.92556316,0.00021906359,0.0048884107,0.009194717],"study_design_scores_gemma":[0.0026685721,0.00007853186,0.32658875,0.0004969449,0.0002132512,0.0001056117,0.003274114,0.064558245,0.58047944,0.005047772,0.01588435,0.0006043849],"about_ca_topic_score_codex":0.000006305004,"about_ca_topic_score_gemma":2.6029767e-7,"teacher_disagreement_score":0.3450837,"about_ca_system_score_codex":0.000034324374,"about_ca_system_score_gemma":0.000058145302,"threshold_uncertainty_score":0.39187592},"labels":[],"label_agreement":null},{"id":"W4393253949","doi":"10.3390/brainsci14040328","title":"Natural Compounds Oridonin and Shikonin Exhibit Potentially Beneficial Regulatory Effects on Select Functions of Microglia","year":2024,"lang":"en","type":"article","venue":"Brain Sciences","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"","keywords":"Microglia; Neuroscience; Natural (archaeology); Chemistry; Biology; Computational biology; Business; Biochemical engineering; Engineering; Inflammation; Immunology","score_opus":0.05616266598585529,"score_gpt":0.3870037681981915,"score_spread":0.3308411022123362,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393253949","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9879266,0.0042871083,0.000040632112,0.0020597244,0.0033715041,0.00018486999,0.000028804721,0.00007629629,0.002024435],"genre_scores_gemma":[0.99743503,0.00004672988,0.00015420167,0.00089727575,0.0003740195,0.0000075942985,0.0000063606003,0.000010085722,0.001068678],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985993,0.00022916813,0.00020380142,0.0004219475,0.0002327629,0.0003130255],"domain_scores_gemma":[0.99899733,0.00070847204,0.00006233324,0.00008615846,0.00005052174,0.000095166186],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008300695,0.00017152276,0.00019595822,0.00020520811,0.00047863368,0.00009945134,0.00021721867,0.00012204437,0.00008863916],"category_scores_gemma":[0.000064770706,0.00013951518,0.000089124434,0.00049257185,0.00061133906,0.00016098972,0.00007501503,0.00037751722,0.000028052718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015683104,0.00016120913,0.008394426,0.00019208631,0.00014517717,0.000053853233,0.00036449268,0.000065339314,0.91040975,0.010883322,0.033917435,0.03525606],"study_design_scores_gemma":[0.001977989,0.0020353196,0.112942174,0.0004897364,0.00029283017,0.00017448272,0.00037521092,0.011707833,0.66363734,0.0022169084,0.20319346,0.0009567273],"about_ca_topic_score_codex":0.000016159549,"about_ca_topic_score_gemma":0.000023308212,"teacher_disagreement_score":0.24677242,"about_ca_system_score_codex":0.000034183333,"about_ca_system_score_gemma":0.0001400858,"threshold_uncertainty_score":0.5689264},"labels":[],"label_agreement":null},{"id":"W4393404987","doi":"10.1080/14786419.2024.2324377","title":"Natural 3,4-dihydro-2(1 <i>h</i> )-quinolinones- Part II: animal, bacterial, and fungal sources","year":2024,"lang":"en","type":"review","venue":"Natural Product Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Drug discovery; Natural (archaeology); Chemistry; Natural compound; Computational biology; Combinatorial chemistry; Biology; Stereochemistry; Biochemical engineering; Biochemistry; Engineering","score_opus":0.38439804901857894,"score_gpt":0.5555658179410089,"score_spread":0.17116776892242996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393404987","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.020915747,0.96592337,1.8073624e-8,0.0010484447,0.008727358,0.0019037927,0.00028416296,0.00021048635,0.0009866483],"genre_scores_gemma":[0.028800862,0.9479095,0.000023555116,0.0001311971,0.006468457,0.00018293597,0.00035859042,0.00014507092,0.015979884],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9921499,0.0023606597,0.00090946775,0.0019550857,0.00090050965,0.0017243964],"domain_scores_gemma":[0.9976338,0.000601488,0.00024277072,0.00064174656,0.0004418081,0.0004383476],"candidate_categories":["metaepi_narrow","sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0033498022,0.0010115585,0.0018744773,0.0007745741,0.0014901584,0.00045933246,0.0011395907,0.0009326562,0.0007174785],"category_scores_gemma":[0.00039471334,0.00071305584,0.000566981,0.001338196,0.0013663461,0.00030711983,0.0019741699,0.010339169,0.00071023504],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003263388,0.00034135533,0.000031273903,0.01912093,0.001263326,0.00055086747,0.00022201356,7.485006e-8,0.0018339166,0.00043779568,0.22973038,0.74614173],"study_design_scores_gemma":[0.00036012367,0.00028824309,0.000014454852,0.002701902,0.0008752205,0.00054426695,0.000026722259,0.000025843583,0.00058746815,0.00006236463,0.99373287,0.00078052795],"about_ca_topic_score_codex":0.00003163375,"about_ca_topic_score_gemma":0.000016735054,"teacher_disagreement_score":0.7640025,"about_ca_system_score_codex":0.00027821935,"about_ca_system_score_gemma":0.0006739724,"threshold_uncertainty_score":0.99980974},"labels":[],"label_agreement":null},{"id":"W4394213598","doi":"10.6084/m9.figshare.13105875","title":"Diosmetin enhances the sensitivity of radiotherapy by suppressing homologous recombination in endometrial cancer","year":2020,"lang":"en","type":"dataset","venue":"Figshare","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Public Health Agency of Canada","funders":"","keywords":"Endometrial cancer; Homologous recombination; Sensitivity (control systems); Homologous chromosome; Cancer research; Radiation therapy; Chemistry; Internal medicine; Oncology; Cancer; Medicine; Biochemistry; Gene; Electronic engineering; Engineering","score_opus":0.14779423918087942,"score_gpt":0.4400885001506572,"score_spread":0.2922942609697778,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394213598","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009381405,0.003021753,8.125209e-7,0.00044273218,0.00091847964,0.0004933518,0.99413234,0.00001742375,0.00003495113],"genre_scores_gemma":[0.016035343,0.0013052743,0.000005590621,0.0007506385,0.00041970628,0.00016890286,0.98124725,0.000018311019,0.00004896851],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973726,0.0013930586,0.00036745422,0.00037613776,0.00019558657,0.00029515443],"domain_scores_gemma":[0.9975843,0.001584545,0.0004844059,0.000187867,0.00008520091,0.0000736947],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003819879,0.00028529926,0.00051458285,0.00013234871,0.00013702472,0.000035059933,0.00038960922,0.00048534377,0.06506608],"category_scores_gemma":[0.0008978646,0.00022692746,0.00014236108,0.0003935835,0.00006712051,0.00007497765,0.00013113047,0.0011610633,0.000119843346],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020014253,0.00020462947,0.00003759358,0.00024638884,0.00014885892,0.000057725287,0.000055328994,0.000012365749,0.008447071,2.026255e-7,0.9857533,0.0048363674],"study_design_scores_gemma":[0.0010824009,0.00007945716,0.00026172324,0.0003764048,0.000055814846,0.0000066667544,0.000012021946,0.00016351989,0.034641616,0.00000478866,0.9630889,0.00022666965],"about_ca_topic_score_codex":0.00015709532,"about_ca_topic_score_gemma":0.0001666631,"teacher_disagreement_score":0.064946234,"about_ca_system_score_codex":0.000106847736,"about_ca_system_score_gemma":0.0001304137,"threshold_uncertainty_score":0.9357886},"labels":[],"label_agreement":null},{"id":"W4394313788","doi":"10.6084/m9.figshare.22226902.v2","title":"φC31 -Mediated Cassette Exchange in Sf9 Insect Cells for Stable Expression","year":2023,"lang":"en","type":"dataset","venue":"Figshare","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"","keywords":"Sf9; Insect; Biology; Cell biology; Chemistry; Botany; Genetics; Gene; Spodoptera; Recombinant DNA","score_opus":0.32576015792847085,"score_gpt":0.4492170574722536,"score_spread":0.12345689954378275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394313788","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016897653,0.0006282241,1.5637931e-7,0.000073256626,0.0016495753,0.0012131878,0.99605674,0.00010436266,0.000105520485],"genre_scores_gemma":[0.00011862947,0.00034451738,0.000010019309,0.0010864682,0.000644659,0.00094617426,0.9955357,0.0000696259,0.0012442274],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99766386,0.0002921973,0.00041679124,0.00064910454,0.0002076283,0.0007704243],"domain_scores_gemma":[0.9979459,0.0010463587,0.00030817976,0.00036001307,0.000120382174,0.00021915215],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00024558842,0.00047434322,0.00054402114,0.00033614162,0.0002141135,0.000055223994,0.00064118026,0.0011306024,0.111861095],"category_scores_gemma":[0.00048491984,0.00046376255,0.00017820478,0.0003792884,0.00002170326,0.00011694856,0.00039986032,0.0012744169,0.012935401],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013754636,0.00022085126,0.00001009419,0.0016453726,0.000063822205,0.000283761,0.000032084572,0.000012402638,0.0019151174,7.3935574e-8,0.9955076,0.00017130395],"study_design_scores_gemma":[0.0013840856,0.00009271526,0.0001351758,0.0011588592,0.000048957416,0.0000033721674,0.000018103277,0.00015930677,0.0064733354,0.0000069954463,0.99001503,0.0005040659],"about_ca_topic_score_codex":0.00009137569,"about_ca_topic_score_gemma":0.00036630893,"teacher_disagreement_score":0.098925695,"about_ca_system_score_codex":0.00014216306,"about_ca_system_score_gemma":0.00016337428,"threshold_uncertainty_score":0.9997814},"labels":[],"label_agreement":null},{"id":"W4394389182","doi":"10.6084/m9.figshare.22226902","title":"φC31 -Mediated Cassette Exchange in Sf9 Insect Cells for Stable Expression","year":2023,"lang":"en","type":"dataset","venue":"Figshare","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"","keywords":"Sf9; Insect; Cell biology; Expression (computer science); Chemistry; Biology; Biophysics; Biological system; Computer science; Botany; Biochemistry; Gene; Spodoptera; Recombinant DNA","score_opus":0.32576015792847085,"score_gpt":0.4492170574722536,"score_spread":0.12345689954378275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394389182","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016897653,0.0006282241,1.5637931e-7,0.000073256626,0.0016495753,0.0012131878,0.99605674,0.00010436266,0.000105520485],"genre_scores_gemma":[0.00011862947,0.00034451738,0.000010019309,0.0010864682,0.000644659,0.00094617426,0.9955357,0.0000696259,0.0012442274],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99766386,0.0002921973,0.00041679124,0.00064910454,0.0002076283,0.0007704243],"domain_scores_gemma":[0.9979459,0.0010463587,0.00030817976,0.00036001307,0.000120382174,0.00021915215],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00024558842,0.00047434322,0.00054402114,0.00033614162,0.0002141135,0.000055223994,0.00064118026,0.0011306024,0.111861095],"category_scores_gemma":[0.00048491984,0.00046376255,0.00017820478,0.0003792884,0.00002170326,0.00011694856,0.00039986032,0.0012744169,0.012935401],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013754636,0.00022085126,0.00001009419,0.0016453726,0.000063822205,0.000283761,0.000032084572,0.000012402638,0.0019151174,7.3935574e-8,0.9955076,0.00017130395],"study_design_scores_gemma":[0.0013840856,0.00009271526,0.0001351758,0.0011588592,0.000048957416,0.0000033721674,0.000018103277,0.00015930677,0.0064733354,0.0000069954463,0.99001503,0.0005040659],"about_ca_topic_score_codex":0.00009137569,"about_ca_topic_score_gemma":0.00036630893,"teacher_disagreement_score":0.098925695,"about_ca_system_score_codex":0.00014216306,"about_ca_system_score_gemma":0.00016337428,"threshold_uncertainty_score":0.9997814},"labels":[],"label_agreement":null},{"id":"W4396531586","doi":"10.32768/abc.2024112159-171","title":"Acquisition of Doxorubicin Resistance Induces Breast Cancer Cell Migration and Epithelial-Mesenchymal Transition that are Reversed by Shikonin-Metformin Synergy","year":2024,"lang":"en","type":"article","venue":"Archives of Breast Cancer","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Genome Canada","funders":"National Institute for Genetic Engineering and Biotechnology","keywords":"Metformin; Doxorubicin; Epithelial–mesenchymal transition; Breast cancer; MCF-7; Cancer research; Chemistry; Drug resistance; Mesenchymal stem cell; Cell; Cancer; Human breast; Medicine; Pharmacology; Internal medicine; Biology; Chemotherapy; Biochemistry; Metastasis; Pathology; Microbiology","score_opus":0.03244131246202887,"score_gpt":0.33774472712549514,"score_spread":0.3053034146634663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396531586","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9761533,0.010744348,0.00020737614,0.0033595809,0.00050187536,0.00022620527,0.007905347,0.00003484649,0.0008670831],"genre_scores_gemma":[0.99015445,0.008648295,0.000082905826,0.0002758101,0.00017874833,0.000049307833,0.00007344132,0.000022900536,0.0005141288],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987058,0.00021003668,0.0002978996,0.00035551435,0.00017002157,0.00026072058],"domain_scores_gemma":[0.9993377,0.00017262326,0.00021238101,0.00011309687,0.0000556096,0.000108587235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016237353,0.00021839348,0.0003069959,0.00010858867,0.00011994368,0.000021019352,0.00013174456,0.00013309464,0.00059516856],"category_scores_gemma":[0.0000017634246,0.00019658978,0.000114171904,0.00016128986,0.0003659498,0.00031686548,0.00003357777,0.0002550579,0.0000017495561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013677336,0.00022105736,0.0063377414,0.0007970869,0.0002334338,0.00001575372,0.0020701992,0.00007952477,0.9577617,0.0002834838,0.0023262866,0.028506003],"study_design_scores_gemma":[0.0018810375,0.000096548596,0.21347994,0.0014520467,0.00046232782,0.00006603071,0.0013064684,0.0024686425,0.7689436,0.00063809386,0.008706976,0.0004982663],"about_ca_topic_score_codex":0.0014071015,"about_ca_topic_score_gemma":0.0010412856,"teacher_disagreement_score":0.20714219,"about_ca_system_score_codex":0.000056832887,"about_ca_system_score_gemma":0.000095018884,"threshold_uncertainty_score":0.8016699},"labels":[],"label_agreement":null},{"id":"W4399272829","doi":"10.1080/14786419.2024.2359545","title":"Biological activity of natural 2-quinolinones","year":2024,"lang":"en","type":"review","venue":"Natural Product Research","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"","keywords":"Traditional medicine; Natural (archaeology); Chemistry; Biology; Medicine","score_opus":0.6530271364491884,"score_gpt":0.6378939548721546,"score_spread":0.015133181577033805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399272829","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0035786096,0.9874743,1.8359123e-7,0.00035818946,0.005623588,0.0014910887,0.00017302706,0.00010745415,0.001193554],"genre_scores_gemma":[0.10200469,0.8905827,0.000029395129,0.0000244001,0.0016346383,0.00009151119,0.00011210034,0.00005485186,0.005465744],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99320996,0.0031554746,0.0006368581,0.0012258127,0.0006918493,0.0010800415],"domain_scores_gemma":[0.9974932,0.00096608885,0.00023332599,0.0005591622,0.0005502266,0.00019798921],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0033985134,0.00061998254,0.0017641431,0.00073071907,0.00033198987,0.00007043862,0.0011893011,0.0008822104,0.00039090717],"category_scores_gemma":[0.0006878941,0.00038017868,0.0007925416,0.0015970102,0.0013311418,0.00012720058,0.0010330144,0.009832123,0.00068877195],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014723146,0.00033004026,0.000014908598,0.014277311,0.00066976825,0.00013262242,0.000044439974,6.8717256e-8,0.0016449329,0.00049983524,0.020329671,0.9619092],"study_design_scores_gemma":[0.0001737907,0.00014589685,0.0000387394,0.0019796484,0.00039106328,0.000109107095,0.000009705567,0.000024196783,0.0018375824,0.0001618205,0.9947215,0.0004069669],"about_ca_topic_score_codex":0.000029418108,"about_ca_topic_score_gemma":0.0000058029627,"teacher_disagreement_score":0.9743918,"about_ca_system_score_codex":0.00025820624,"about_ca_system_score_gemma":0.00056977896,"threshold_uncertainty_score":0.999865},"labels":[],"label_agreement":null},{"id":"W4399492323","doi":"10.1080/07373937.2024.2362822","title":"Exploring forced convective solar drying of henna ( <i>Lawsonia inermis</i> ) and its effect on the biological activities: Comparison with open sun dried product","year":2024,"lang":"en","type":"article","venue":"Drying Technology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick","funders":"","keywords":"Lawsonia inermis; Product (mathematics); Environmental science; Food science; Chemistry; Mathematics; Traditional medicine","score_opus":0.29547713584984503,"score_gpt":0.4255185682793731,"score_spread":0.1300414324295281,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399492323","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99315333,0.0011610488,0.00007082656,0.0024257062,0.0005316143,0.0011382168,0.000027788506,0.00030670982,0.0011847479],"genre_scores_gemma":[0.9988555,0.00025217715,0.00006554949,0.00025708642,0.00007713527,0.00036796805,0.000007654839,0.000034956316,0.000082029204],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998096,0.00039108418,0.00029725718,0.0006292022,0.00012132114,0.0004651683],"domain_scores_gemma":[0.9984195,0.0010311913,0.0001499357,0.00026970048,0.00006145981,0.00006819603],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00083204074,0.00032599593,0.00057333795,0.00024775247,0.00043773022,0.00007256145,0.0005911051,0.0002629123,0.000054204087],"category_scores_gemma":[0.0001691017,0.00020594284,0.00006360223,0.0005813488,0.00064154895,0.00023381054,0.00048746442,0.0012662869,0.000015112032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015389088,0.0002973378,0.042519305,0.00031459855,0.00084654527,0.00012047954,0.0015015131,0.000028381022,0.8867785,0.039119456,0.00048897933,0.026446018],"study_design_scores_gemma":[0.0010800025,0.0015837029,0.0008422807,0.00028253766,0.000117927746,0.000053901982,0.00072373153,0.0011215025,0.9796807,0.00048931607,0.0137137445,0.0003106426],"about_ca_topic_score_codex":0.000014357394,"about_ca_topic_score_gemma":0.000010066699,"teacher_disagreement_score":0.09290223,"about_ca_system_score_codex":0.000066051005,"about_ca_system_score_gemma":0.000056566965,"threshold_uncertainty_score":0.83981055},"labels":[],"label_agreement":null},{"id":"W4400029612","doi":"10.1002/cptc.202400164","title":"Antimicrobial Efficacy of Photocaged β‐Lapachone in <i>Bacillus subtilis</i> Biofilms","year":2024,"lang":"en","type":"article","venue":"ChemPhotoChem","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"Bacillus subtilis; Antimicrobial; Biofilm; Microbiology; Chemistry; Biology; Bacteria","score_opus":0.09421651471096844,"score_gpt":0.4088654984975214,"score_spread":0.314648983786553,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400029612","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98806435,0.0011093906,0.00001658854,0.00022364421,0.0012308412,0.00071536464,0.000118416916,0.00012852991,0.008392904],"genre_scores_gemma":[0.99795353,0.00023950645,0.00013118083,0.0005134045,0.00017948996,0.000058172136,0.000054396834,0.000038189457,0.00083210284],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983345,0.00011562077,0.00045797467,0.00048143734,0.00014616016,0.00046425028],"domain_scores_gemma":[0.9992199,0.00025632855,0.00008256867,0.00024154338,0.00005420571,0.00014547179],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00044833924,0.00028228358,0.00039300372,0.00020650409,0.000070934104,0.00003238022,0.00032185664,0.00033574246,0.0011826617],"category_scores_gemma":[0.0000522041,0.00026976908,0.0002070848,0.00064188143,0.00033788665,0.00010958149,0.00010874472,0.0007244819,0.00015797425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033845365,0.00058316585,0.0032206182,0.00027975338,0.00011486491,0.00018324675,0.00071841094,0.000012184086,0.9798145,0.000097547556,0.011244831,0.0033924237],"study_design_scores_gemma":[0.0019728022,0.00005012633,0.0014938556,0.00012217293,0.000056268567,0.000033658926,0.00006668424,0.0007132375,0.93620443,0.000034748544,0.05898457,0.00026742803],"about_ca_topic_score_codex":0.000047778027,"about_ca_topic_score_gemma":0.000012952378,"teacher_disagreement_score":0.04773974,"about_ca_system_score_codex":0.00009386865,"about_ca_system_score_gemma":0.00012685903,"threshold_uncertainty_score":0.99997544},"labels":[],"label_agreement":null},{"id":"W4401715378","doi":"10.1007/s11274-024-04109-5","title":"Chemical optimization and derivatization of micrococcin p2 to target multiple bacterial infections: new antibiotics from thiopeptides","year":2024,"lang":"en","type":"review","venue":"World Journal of Microbiology and Biotechnology","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Korea National Institute of Health; National Research Foundation of Korea","keywords":"Antibiotics; Antimicrobial; Drug development; Microbiology; Computational biology; Drug resistance; Staphylococcus aureus; Biology; Chemistry; Drug; Bacteria; Pharmacology","score_opus":0.06629815383344806,"score_gpt":0.3800278670475976,"score_spread":0.31372971321414955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401715378","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.019280607,0.9755334,0.0017825661,0.0007834603,0.0017522,0.0004473275,0.0003667042,0.00003797203,0.000015710873],"genre_scores_gemma":[0.006778514,0.98098934,0.011300474,0.00017644606,0.00041424198,0.0000013299133,0.00018478638,0.000034893113,0.000120001416],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980793,0.00026951142,0.00097409566,0.0003765042,0.00003425453,0.00026632112],"domain_scores_gemma":[0.99855846,0.0003199664,0.00074952294,0.00013507574,0.00010478381,0.0001322058],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0002994662,0.0003902326,0.0013730233,0.00079671043,0.000092301896,0.000024692637,0.0002773683,0.0013940572,0.0001655898],"category_scores_gemma":[0.00014634048,0.00030325487,0.00019676304,0.0004904963,0.00043125392,0.00006340876,0.00029744356,0.001254384,0.000010453184],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032920574,0.00041161405,0.00068114506,0.002417536,0.002186356,0.00009438709,0.00015722122,0.000048609774,0.7053464,0.00036942074,0.011259918,0.2766982],"study_design_scores_gemma":[0.00072434515,0.00023446241,0.0000064129376,0.0018036505,0.0012861553,0.00088722294,0.000017916918,0.000028602275,0.051810395,0.00010554566,0.94280136,0.00029393812],"about_ca_topic_score_codex":0.000011685758,"about_ca_topic_score_gemma":0.000029383687,"teacher_disagreement_score":0.93154144,"about_ca_system_score_codex":0.000058248464,"about_ca_system_score_gemma":0.00018966703,"threshold_uncertainty_score":0.99994195},"labels":[],"label_agreement":null},{"id":"W4402315477","doi":"10.1016/j.jics.2024.101347","title":"DFT and molecular docking studies of 10-hydroxylstrictosamide from methanol leaves extract of Sarcocephallus latifolius (Smith, Bruce)","year":2024,"lang":"en","type":"article","venue":"Journal of the Indian Chemical Society","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Regina","funders":"Aalborg Universitet; Association of Arab Universities","keywords":"Chemistry; Methanol; Docking (animal); Stereochemistry; Computational chemistry; Organic chemistry","score_opus":0.1012638268708658,"score_gpt":0.42355949570385354,"score_spread":0.32229566883298777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402315477","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97531426,0.02285907,0.00003233396,0.000980513,0.00054163573,0.00008357224,0.00006043498,0.000007842657,0.000120345656],"genre_scores_gemma":[0.9969199,0.0020208454,0.0005130844,0.00025483183,0.00022542285,9.095448e-7,9.815697e-7,0.000015072406,0.000048987295],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870753,0.00015864024,0.00053024886,0.00015343851,0.00024971474,0.00020041327],"domain_scores_gemma":[0.99853337,0.0007036097,0.0004231988,0.000107000626,0.00013034808,0.00010245521],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005012735,0.00016677933,0.00043241854,0.000039230126,0.00007841267,0.00001776528,0.00031860033,0.0002181518,0.00011118764],"category_scores_gemma":[0.00014031322,0.00011120293,0.000502387,0.00020700521,0.0004809595,0.000103318955,0.0001748099,0.00079891685,0.0000013009297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007725867,0.00013026047,0.005144337,0.0002431245,0.0021423926,0.00006235234,0.003628602,0.00004624311,0.9818146,0.000046307337,0.0027403205,0.0039241794],"study_design_scores_gemma":[0.0006487981,0.000056366578,0.0016565701,0.00030990897,0.00047894736,0.00006498999,0.000805897,0.0004297378,0.9894338,0.0020771862,0.0039117457,0.0001260022],"about_ca_topic_score_codex":0.000010502349,"about_ca_topic_score_gemma":6.1003635e-7,"teacher_disagreement_score":0.021605615,"about_ca_system_score_codex":0.00007900791,"about_ca_system_score_gemma":0.00010420801,"threshold_uncertainty_score":0.45347238},"labels":[],"label_agreement":null},{"id":"W4402730103","doi":"10.1139/cjc-2024-0105","title":"A 1,4-benzoquinone with counteracting inductive donor and acceptor substituents","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Lethbridge","funders":"","keywords":"Chemistry; 1,4-Benzoquinone; Acceptor; Benzoquinone; Photochemistry; Stereochemistry; Quinone; Medicinal chemistry; Organic chemistry","score_opus":0.07086828356438153,"score_gpt":0.374127868868852,"score_spread":0.3032595853044705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402730103","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922971,0.0023524812,0.000024302746,0.00054075057,0.0007289816,0.00004687652,0.00004433366,0.000007873759,0.003957264],"genre_scores_gemma":[0.9985734,0.0000672266,0.00006656729,0.0002402056,0.00046257887,0.000001683175,0.0000036099927,0.000015186983,0.0005695338],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99932474,0.000029787981,0.00019180984,0.000120848,0.0000830685,0.000249757],"domain_scores_gemma":[0.99907154,0.00008038441,0.000103686834,0.000054256867,0.00012702454,0.00056309224],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018815589,0.00013159878,0.0001640333,0.000071482325,0.00014562596,0.0001046084,0.00013899402,0.00012449088,0.0012851675],"category_scores_gemma":[0.00003191531,0.00010806929,0.000046247,0.00011648868,0.00020082056,0.00022268789,0.000011458125,0.00072228425,0.000007984661],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00077725295,0.00019430007,0.2980477,0.001134809,0.0029490062,0.01566286,0.008485451,0.00008369823,0.60016364,0.00025441396,0.033411548,0.038835328],"study_design_scores_gemma":[0.0027500468,0.00024583878,0.011622282,0.00081454363,0.0005103293,0.010896164,0.004014492,0.0003393808,0.3072279,0.0002324227,0.6605369,0.0008097275],"about_ca_topic_score_codex":0.00018252157,"about_ca_topic_score_gemma":0.00034200656,"teacher_disagreement_score":0.6271253,"about_ca_system_score_codex":0.00014049943,"about_ca_system_score_gemma":0.00074005366,"threshold_uncertainty_score":0.99962777},"labels":[],"label_agreement":null},{"id":"W4403457707","doi":"10.1021/jacs.4c11897","title":"A Divergent Synthesis of Numerous Pyrroloiminoquinone Alkaloids Identifies Promising Antiprotozoal Agents","year":2024,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Division of Chemistry; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Deutsche Forschungsgemeinschaft; National Institute of Allergy and Infectious Diseases; Université de Sherbrooke; Steven and Alexandra Cohen Foundation; National Cancer Institute; National Institutes of Health; Yale University; National Science Foundation","keywords":"Antiprotozoal; Chemistry; Computational biology; Biochemistry; In vitro","score_opus":0.0751903830104151,"score_gpt":0.3987592335600924,"score_spread":0.3235688505496773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403457707","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960356,0.00072630664,0.000089406276,0.0016616178,0.001102997,0.00017017419,0.00003459785,0.000019720874,0.00015961292],"genre_scores_gemma":[0.9979292,0.0005226574,0.00042591232,0.0006084953,0.00034756234,0.0000073448896,6.9801933e-7,0.000020538377,0.00013758657],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984345,0.00018913775,0.0005329149,0.00018799429,0.0003606858,0.00029476287],"domain_scores_gemma":[0.9987173,0.00030546985,0.00058224134,0.0001478239,0.00011524888,0.00013191046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006039879,0.00018493025,0.00045754333,0.00003564222,0.00014226705,0.00003841305,0.00054446975,0.00010164789,0.00018632115],"category_scores_gemma":[0.00010517932,0.000121195524,0.0008743929,0.00037698707,0.0008622807,0.00011745447,0.00023079113,0.00076216535,0.000008252664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020946757,0.00033574473,0.012733308,0.00015124082,0.0010637317,0.00002954621,0.00071818166,0.000019437792,0.9565281,0.000021854728,0.019995002,0.00819433],"study_design_scores_gemma":[0.0003663833,0.0000976266,0.0070114387,0.000190769,0.0005360727,0.00013352292,0.00045191846,0.0009133331,0.9787765,0.00021280212,0.011134238,0.00017539877],"about_ca_topic_score_codex":0.000021395828,"about_ca_topic_score_gemma":2.6002792e-7,"teacher_disagreement_score":0.02224834,"about_ca_system_score_codex":0.0001329084,"about_ca_system_score_gemma":0.000104507024,"threshold_uncertainty_score":0.49422103},"labels":[],"label_agreement":null},{"id":"W4407922968","doi":"10.1007/978-3-031-76859-0_8","title":"Role of Biotechnology in the Production of Health Promising Bioactive Molecules","year":2025,"lang":"en","type":"book-chapter","venue":"Sustainable landscape planning and natural resources management","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Biotechnology; Production (economics); Biochemical engineering; Computational biology; Nanotechnology; Biology; Chemistry; Engineering; Materials science","score_opus":0.028284447032203782,"score_gpt":0.3413844071595324,"score_spread":0.3130999601273286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407922968","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.30879033,0.18007192,0.000030781644,0.0067478945,0.00076465285,0.004084377,0.00006589337,0.00012352808,0.49932063],"genre_scores_gemma":[0.9223395,0.0019760542,0.00007229207,0.00015830497,0.000039148264,0.000017593013,0.00003487105,0.000014369083,0.07534786],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985725,0.0001617432,0.0004008642,0.00036032085,0.0001689812,0.00033557435],"domain_scores_gemma":[0.9991326,0.00013297707,0.0004468703,0.0001906139,0.00007092318,0.000026031606],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00083457556,0.00024719592,0.00044924574,0.0005771067,0.00019378068,0.000016367741,0.0002698383,0.00026765995,0.000014114731],"category_scores_gemma":[0.00004056094,0.00018232649,0.000072752344,0.00016874012,0.00022752398,0.000040357216,0.00022602608,0.0007114017,4.4089273e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003251553,0.00072957686,0.009456072,0.014341466,0.0029771016,0.00050724315,0.01393297,0.00051838055,0.0014256008,0.67242706,0.01768157,0.2627514],"study_design_scores_gemma":[0.0015345126,0.00058371696,0.0062652538,0.002160673,0.000475585,0.000029033132,0.052143786,0.00082946883,0.0026274957,0.0144010885,0.918314,0.0006353912],"about_ca_topic_score_codex":0.000045076013,"about_ca_topic_score_gemma":0.0000056665144,"teacher_disagreement_score":0.90063244,"about_ca_system_score_codex":0.00007905024,"about_ca_system_score_gemma":0.000038669597,"threshold_uncertainty_score":0.7435059},"labels":[],"label_agreement":null},{"id":"W4411217546","doi":"10.1017/s0885715625100791","title":"Crystal structure of anisomycin, C <sub>14</sub> H <sub>19</sub> NO <sub>4</sub>","year":2025,"lang":"en","type":"article","venue":"Powder Diffraction","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Canadian Light Source; Natural Sciences and Engineering Research Council of Canada; International Centre for Diffraction Data","keywords":"Anisomycin; Crystal (programming language); Crystallography; Materials science; Chemistry; Computer science","score_opus":0.03752004503595048,"score_gpt":0.3517655192534208,"score_spread":0.31424547421747034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411217546","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98828894,0.000696193,0.0006767203,0.0007885593,0.0055942666,0.0007522207,0.00032908242,0.0002148916,0.002659126],"genre_scores_gemma":[0.9952309,0.001244676,0.000049277613,0.0022549357,0.00070384785,0.000043230822,0.00022230057,0.00007403873,0.00017675573],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962917,0.0005852808,0.00085685635,0.0009105122,0.0004513228,0.00090430886],"domain_scores_gemma":[0.9976149,0.00041082152,0.00060115586,0.0005145869,0.0004998033,0.0003586839],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040245734,0.00067258097,0.00073131017,0.0004413764,0.0006785288,0.00008935576,0.00043439498,0.0009077479,0.000339184],"category_scores_gemma":[0.00019935459,0.0006823329,0.0003848051,0.0007098079,0.0004015287,0.000550629,0.0002456154,0.0016527327,0.0002302507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007892021,0.0007662328,0.011211272,0.00030909813,0.0005482844,0.000040909443,0.00019097817,0.00010962312,0.944433,0.0003980999,0.02284068,0.018362647],"study_design_scores_gemma":[0.0024981615,0.00018065488,0.04650806,0.0000860751,0.00046221193,0.000050106424,0.00014786191,0.0008029991,0.9237693,0.0011886428,0.023737123,0.00056879607],"about_ca_topic_score_codex":0.000028513216,"about_ca_topic_score_gemma":0.00008477824,"teacher_disagreement_score":0.035296787,"about_ca_system_score_codex":0.000327386,"about_ca_system_score_gemma":0.00027091912,"threshold_uncertainty_score":0.9995628},"labels":[],"label_agreement":null},{"id":"W4411849427","doi":"10.1038/s41598-025-07397-5","title":"Barleria extracts containing barlerin and verbascoside boost immunity and regulate CYP450 gene in prostate cancer","year":2025,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Khon Kaen University","keywords":"Verbascoside; Prostate cancer; Immunity; Medicine; Cancer research; Biology; Traditional medicine; Bioinformatics; Cancer; Internal medicine; Immunology; Immune system; Botany","score_opus":0.06323950557552281,"score_gpt":0.4021994093565906,"score_spread":0.3389599037810678,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411849427","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882619,0.004286926,0.000009972189,0.0004463887,0.004664627,0.00042674222,0.000013866908,0.00003802836,0.0018515899],"genre_scores_gemma":[0.99543154,0.0005349919,0.000093810464,0.00028844204,0.00003033717,0.000046848883,0.000021681504,0.000011302272,0.0035410202],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9981575,0.00020931709,0.0004548088,0.00063423614,0.00013127847,0.00041284968],"domain_scores_gemma":[0.99917394,0.00008915219,0.00018705135,0.0002947478,0.00009967368,0.00015541623],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017774866,0.0001944347,0.0002737152,0.00021096582,0.00054138113,0.00019379689,0.000099341414,0.00012333156,0.00020610938],"category_scores_gemma":[0.000086326916,0.00018774347,0.000036782294,0.0003647955,0.0005767208,0.00022575413,0.00021905126,0.00041247765,0.000003124633],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027517095,0.0001605494,0.45882872,0.00010451282,0.000097429765,0.0010242095,0.001089439,0.00009771397,0.5240267,0.00016531635,0.0041740187,0.009956242],"study_design_scores_gemma":[0.0016886082,0.00006153151,0.60998654,0.00023661806,0.00010448307,0.00024942803,0.00041660876,0.0011698001,0.2131658,0.003493936,0.16896418,0.00046246618],"about_ca_topic_score_codex":0.0002687637,"about_ca_topic_score_gemma":0.00026847693,"teacher_disagreement_score":0.3108609,"about_ca_system_score_codex":0.00007480727,"about_ca_system_score_gemma":0.00019640873,"threshold_uncertainty_score":0.7655956},"labels":[],"label_agreement":null},{"id":"W4412009955","doi":"10.1039/d5sc03363b","title":"Chemical diversification of polyprenyl quinones for mechanistic studies on menaquinone-binding peptide antibiotics","year":2025,"lang":"en","type":"article","venue":"Chemical Science","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Queen's University; Universiteit Utrecht; Universiteit Leiden; Queen's University Belfast; Department for the Economy; UK Research and Innovation","keywords":"Antibiotics; Peptide; Chemistry; Diversification (marketing strategy); Biochemistry; Business","score_opus":0.19580930799303298,"score_gpt":0.48477505164754986,"score_spread":0.2889657436545169,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412009955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99606836,0.00011246763,0.00044169847,0.0004496775,0.00089765934,0.0002592743,0.00004289759,0.000032099575,0.0016958594],"genre_scores_gemma":[0.99847835,0.00004818731,0.0008375836,0.00028683458,0.000058512658,0.000004855644,0.0000084299445,0.0000048307024,0.0002724084],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988171,0.000027992292,0.00025853975,0.00038517377,0.00018370035,0.0003275342],"domain_scores_gemma":[0.9989618,0.00045346646,0.00012833317,0.00015173937,0.00020459438,0.00010003849],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005389445,0.00013997326,0.00022983782,0.000111226844,0.00027075983,0.000016453178,0.0004585918,0.000112146095,0.000021513613],"category_scores_gemma":[0.00052605866,0.00012122474,0.0000765618,0.00046953338,0.0011297073,0.00008080103,0.00019605727,0.00018842568,0.000009743834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001586331,0.00019747762,0.00091362157,0.00009760978,0.00004966637,0.0000010191065,0.00015725648,0.000005404717,0.9783638,0.018363899,0.0007744099,0.0009172133],"study_design_scores_gemma":[0.0005144147,0.000056505538,0.00014559725,0.000067439505,0.00007910173,0.0000011184463,0.0003003529,0.0010694681,0.99547154,0.001488366,0.0006844861,0.000121590514],"about_ca_topic_score_codex":0.0000017325948,"about_ca_topic_score_gemma":2.7671825e-7,"teacher_disagreement_score":0.01710777,"about_ca_system_score_codex":0.00014700241,"about_ca_system_score_gemma":0.000087620705,"threshold_uncertainty_score":0.49434015},"labels":[],"label_agreement":null},{"id":"W4413270568","doi":"10.1016/j.tiv.2025.106129","title":"Transcriptomic points of departure for 6PPD-Quinone derived from human Caco-2 and HepG2 cells","year":2025,"lang":"en","type":"article","venue":"Toxicology in Vitro","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Environment and Climate Change Canada; Génome Québec","keywords":"Caco-2; Transcriptome; Quinone; Chemistry; Computational biology; Cell biology; Biology; Biochemistry; In vitro; Gene; Gene expression","score_opus":0.07337825411041567,"score_gpt":0.41460504297571954,"score_spread":0.3412267888653039,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413270568","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99423206,0.00089334644,0.00029708171,0.0013443361,0.0011098825,0.00067167985,0.0004274093,0.00003579423,0.000988424],"genre_scores_gemma":[0.9955459,0.00012593837,0.0009952815,0.002646765,0.000086099164,0.00009591828,0.00007491162,0.000017840086,0.0004112993],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99829614,0.00031908118,0.0004626162,0.00042593514,0.000059966173,0.00043623705],"domain_scores_gemma":[0.99901587,0.00051407394,0.00013671318,0.00017294679,0.000058638376,0.00010177868],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033792242,0.00024487043,0.0005569391,0.00020132467,0.00017617889,0.000010077063,0.0002600084,0.00053447473,0.0002880765],"category_scores_gemma":[0.000032673986,0.00025082813,0.00011650613,0.00015912925,0.0004424394,0.00006549092,0.00007457953,0.00049226714,0.000005906014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013061685,0.0005183275,0.009802588,0.00008394811,0.00022474932,0.000021419233,0.000349343,0.000005166298,0.98344404,0.0006312503,0.0022360354,0.0013769728],"study_design_scores_gemma":[0.004844562,0.00019476362,0.03611907,0.000024899751,0.00020067266,0.000003242708,0.00013297914,0.00037432023,0.94529027,0.0027444877,0.009861908,0.00020880294],"about_ca_topic_score_codex":0.000068683206,"about_ca_topic_score_gemma":0.00030727262,"teacher_disagreement_score":0.038153738,"about_ca_system_score_codex":0.00006640431,"about_ca_system_score_gemma":0.00007053562,"threshold_uncertainty_score":0.9999944},"labels":[],"label_agreement":null},{"id":"W4414484387","doi":"10.1016/j.microc.2025.115484","title":"Ultrasonic-assisted extraction of bioactives from Eleutherococcus senticosus using deep eutectic solvents: Optimization and α-glucosidase inhibitory assessment","year":2025,"lang":"en","type":"article","venue":"Microchemical Journal","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nutrasource","funders":"Natural Science Foundation of Heilongjiang Province; Natural Science Foundation of Ningxia Province","keywords":"Nutraceutical; Extraction (chemistry); Araliaceae; Ginseng; Palmitic acid; IC50","score_opus":0.06581613164905971,"score_gpt":0.4354747996897035,"score_spread":0.3696586680406438,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414484387","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93831587,0.001538167,0.058893625,0.00014915086,0.00072861026,0.00014582285,0.000027930586,0.000020626372,0.00018018708],"genre_scores_gemma":[0.9900524,0.0004713271,0.009038184,0.00020137505,0.00016888764,0.0000038043368,0.00002050441,0.000014186118,0.000029308643],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99861586,0.0002720632,0.00045596794,0.0002612582,0.0001284372,0.0002663987],"domain_scores_gemma":[0.9990051,0.00024301505,0.00033858806,0.000092882095,0.00017448691,0.00014594426],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026047093,0.0002000247,0.00028191652,0.00015343502,0.00029786926,0.000060639188,0.00013558524,0.00026775224,0.0002487022],"category_scores_gemma":[0.00004181435,0.00019148366,0.000118209035,0.00019073175,0.00021868691,0.00018554927,0.000067936824,0.00082990853,0.000001356359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025263833,0.0005983617,0.013370731,0.00003855957,0.00038762225,0.000018053217,0.00010102711,0.0004357496,0.9803311,0.000013354529,0.00012237755,0.0043304036],"study_design_scores_gemma":[0.002484724,0.000052205945,0.010170475,0.00016173787,0.00045884773,0.00016031659,0.000510708,0.018174091,0.9666934,0.00018051459,0.00074042456,0.00021255085],"about_ca_topic_score_codex":0.00001886545,"about_ca_topic_score_gemma":0.000002558881,"teacher_disagreement_score":0.05173654,"about_ca_system_score_codex":0.00023760009,"about_ca_system_score_gemma":0.00012103501,"threshold_uncertainty_score":0.78084767},"labels":[],"label_agreement":null},{"id":"W6903111281","doi":"10.1021/np020144m.s001","title":"Antineoplastic Agents. 488. Isolation and Structure of Yukonin from a Yukon\\nTerritory Fungus","year":2016,"lang":"en","type":"article","venue":"Figshare","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Fungus; Isolation (microbiology); Cancer cell lines; Lactone; Cell culture; Cancer","score_opus":0.12036092761080033,"score_gpt":0.38844639548824283,"score_spread":0.2680854678774425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6903111281","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7892423,0.0006469427,0.000014183455,0.0001330468,0.00045591776,0.00017528248,0.20865704,0.000043223135,0.0006320222],"genre_scores_gemma":[0.99335176,0.000025470626,0.0000520918,0.00025887467,0.00025668976,0.000008854578,0.0057440246,0.000016654509,0.00028559973],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9991078,0.000113781505,0.0002069807,0.00025959258,0.00010103729,0.00021084036],"domain_scores_gemma":[0.99920744,0.000317768,0.00015894866,0.00012511786,0.000076580625,0.00011417733],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000028087532,0.00016427848,0.0001942723,0.000060071394,0.000092946575,0.000013088323,0.00014927286,0.00020955244,0.14197943],"category_scores_gemma":[0.00018086992,0.00012066881,0.00005482026,0.00007008084,0.000039802308,0.00012724078,0.00010964309,0.00018713453,0.00018832154],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000389781,0.00021794254,0.07046602,0.00026388592,0.00036323487,0.00008616448,0.00053211296,0.000010868456,0.5615341,0.00006697029,0.34259918,0.023469733],"study_design_scores_gemma":[0.0038366844,0.00021999351,0.4969947,0.0013206901,0.00014654682,0.000036054484,0.000062989115,0.0015991756,0.13276413,0.00039286696,0.36204624,0.00057992805],"about_ca_topic_score_codex":0.000010531396,"about_ca_topic_score_gemma":0.0000224724,"teacher_disagreement_score":0.42876998,"about_ca_system_score_codex":0.000022500755,"about_ca_system_score_gemma":0.00003441849,"threshold_uncertainty_score":0.85880494},"labels":[],"label_agreement":null},{"id":"W6922013865","doi":"10.1021/jo701435p.s002","title":"Total Synthesis of Streptonigrone","year":2016,"lang":"en","type":"article","venue":"Figshare","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Total synthesis; Quinoline; Key (lock); Surface modification; Chemical synthesis","score_opus":0.17342515163726435,"score_gpt":0.4160903991115327,"score_spread":0.24266524747426838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6922013865","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.45826378,0.00057773676,0.0000067199594,0.0009352345,0.000563807,0.00037359467,0.49515367,0.00016086173,0.04396459],"genre_scores_gemma":[0.99749446,0.000013039728,0.000025935975,0.00011208826,0.000108019776,0.000054805667,0.00085772807,0.000011513803,0.0013224315],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999312,0.00008470876,0.00015415478,0.00016080478,0.000085772896,0.00020255176],"domain_scores_gemma":[0.9991795,0.00043053032,0.0000945315,0.00012856965,0.00007386105,0.000092999275],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00005302906,0.00010388714,0.0001485115,0.000044556153,0.000059332673,0.000004592734,0.00015892467,0.00012439644,0.45381492],"category_scores_gemma":[0.00039788053,0.00007061108,0.00008554678,0.00007960132,0.000028012264,0.00007633492,0.0000819563,0.00009835944,0.002002579],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014293967,0.00037906235,0.0066229613,0.00017330269,0.00022066418,0.00004788675,0.00006837651,0.0000036723272,0.1386432,0.00018457702,0.71309406,0.14041927],"study_design_scores_gemma":[0.0006196139,0.0000688316,0.027972708,0.0005411314,0.000034975357,0.000015210737,0.000022817727,0.000042334388,0.65386224,0.000048203114,0.31655815,0.00021376985],"about_ca_topic_score_codex":0.000001454934,"about_ca_topic_score_gemma":0.0000013226088,"teacher_disagreement_score":0.53923064,"about_ca_system_score_codex":0.000021803846,"about_ca_system_score_gemma":0.000033326964,"threshold_uncertainty_score":0.99877447},"labels":[],"label_agreement":null},{"id":"W6931947712","doi":"10.5284/1073017","title":"Excavations at Brampton, Huntingdonshire, 1966","year":2008,"lang":"en","type":"article","venue":"Archaeology Data Service","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Beaker; Ditch; Pottery; Excavation; Enclosure; Settlement (finance)","score_opus":0.41820267146585904,"score_gpt":0.4626168144329698,"score_spread":0.04441414296711077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931947712","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9819111,0.00043830092,0.0002816957,0.008843986,0.0011202692,0.000262482,0.0006890702,0.00018214116,0.0062709507],"genre_scores_gemma":[0.9742908,0.00055322866,0.0014115137,0.018439496,0.00033349727,0.000026332717,0.002303825,0.000031582185,0.0026097426],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.99779016,0.00040173778,0.00035818355,0.0006764201,0.00015204384,0.00062147697],"domain_scores_gemma":[0.9979393,0.00049829716,0.00015868947,0.0010166517,0.00015353579,0.0002335357],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00047565592,0.0002526439,0.00028886856,0.00012117318,0.00087329966,0.0000058040755,0.0014652819,0.00030220754,0.0030633567],"category_scores_gemma":[0.00010667699,0.000254999,0.000049897317,0.00041147665,0.00082416786,0.00031894766,0.0027259255,0.0006476039,0.0015781755],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032865297,0.000545141,0.87952495,0.000076963704,0.0003738682,0.00038543832,0.002921159,0.000048342572,0.01240188,0.004247906,0.097045824,0.0020998798],"study_design_scores_gemma":[0.0012226218,0.000051218314,0.15365775,0.00000763125,0.00008588607,0.0005868197,0.00007678211,0.0029133402,0.0023149827,0.00055411865,0.83820134,0.000327489],"about_ca_topic_score_codex":0.00035675653,"about_ca_topic_score_gemma":0.0019251296,"teacher_disagreement_score":0.74115556,"about_ca_system_score_codex":0.00004769829,"about_ca_system_score_gemma":0.000106484804,"threshold_uncertainty_score":0.9999902},"labels":[],"label_agreement":null},{"id":"W6949812030","doi":"10.5281/zenodo.5310344","title":"Falcaustra catesbeianae Walton 1929","year":2010,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"South carolina; Square (algebra); West virginia; George (robot); New england","score_opus":0.13934159238546534,"score_gpt":0.38954928419798474,"score_spread":0.2502076918125194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6949812030","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6497893,0.00008600119,0.00056773284,0.0022143824,0.0014827653,0.0005543651,0.00039534763,0.001072707,0.34383744],"genre_scores_gemma":[0.99545926,0.00008150093,0.000120621415,0.00053383486,0.00034847352,4.7328175e-8,0.0006461043,0.0005930765,0.0022170632],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99849445,0.00029876505,0.0002081249,0.00036464428,0.00018760737,0.00044640052],"domain_scores_gemma":[0.99896216,0.00003309399,0.00008755043,0.00029588633,0.00032629463,0.0002950331],"candidate_categories":["sts","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00065984065,0.0001582305,0.00013731491,0.0001471845,0.0022989332,0.00028308653,0.0008265297,0.00017391003,0.050190344],"category_scores_gemma":[0.00022246578,0.00016107962,0.00006452455,0.00032462724,0.00031411735,0.00017267524,0.00054966216,0.00096604746,0.010669603],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016966856,0.0006030487,0.00020120465,0.00006115304,0.00014024852,0.00007237578,0.0008154444,0.000018349096,0.31856355,0.0152396755,0.40424445,0.25987083],"study_design_scores_gemma":[0.0006083646,0.000118250806,0.0023470279,0.000005705714,0.000025184272,0.000112170506,0.00009707794,0.00024209886,0.013588045,0.00017389107,0.98249733,0.00018486104],"about_ca_topic_score_codex":0.000015216802,"about_ca_topic_score_gemma":0.0000014133398,"teacher_disagreement_score":0.57825285,"about_ca_system_score_codex":0.00005175068,"about_ca_system_score_gemma":0.0000044985545,"threshold_uncertainty_score":0.99899995},"labels":[],"label_agreement":null},{"id":"W6955061624","doi":"10.57745/2hcot6","title":"readme_raw_data_rmqs2.txt","year":2024,"lang":"te","type":"dataset","venue":"Recherche Data Gouv France","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Nautical Research Society","funders":"","keywords":"Process (computing); Work (physics); Product (mathematics); Identification (biology)","score_opus":0.6725552076811092,"score_gpt":0.5763692958828016,"score_spread":0.0961859117983076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6955061624","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00024742147,0.025303574,0.00017732549,0.0028681292,0.013806104,0.0012374633,0.9532096,0.00031253186,0.0028378419],"genre_scores_gemma":[0.00019712765,0.084161274,0.0020726088,0.0051013306,0.0039249863,0.00010921853,0.8927825,0.00021631773,0.0114346],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.98639894,0.005161055,0.0016603309,0.0039550206,0.00081862195,0.002006018],"domain_scores_gemma":[0.9879476,0.003162039,0.0007845112,0.0069178585,0.00028341467,0.0009045884],"candidate_categories":["metaepi_narrow","open_science","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"category_scores_codex":[0.009228524,0.0018476989,0.0018239825,0.0004322962,0.00072312687,0.00055150525,0.009989825,0.0056810994,0.01928141],"category_scores_gemma":[0.0019087433,0.0018241837,0.0004079492,0.0017195528,0.001216379,0.0010194058,0.0067848247,0.014597682,0.15735966],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031603838,0.0011527587,0.0002988977,0.0023396362,0.0020968996,0.0011822187,0.00009709652,0.000003610454,0.00088155514,0.00012413946,0.96460557,0.02690156],"study_design_scores_gemma":[0.0013137625,0.00019647653,0.00016821532,0.000973431,0.0025614651,0.000200533,0.00009703602,0.0019549127,0.000667775,0.00053055416,0.9894361,0.0018997315],"about_ca_topic_score_codex":0.0004601183,"about_ca_topic_score_gemma":0.00029944154,"teacher_disagreement_score":0.13807824,"about_ca_system_score_codex":0.0006812704,"about_ca_system_score_gemma":0.0016930136,"threshold_uncertainty_score":0.9994268},"labels":[],"label_agreement":null},{"id":"W6977690332","doi":"10.6084/m9.figshare.c.6119193.v1","title":"Quantitatively assessing aging effects in rapid motor behaviours: a cross-sectional study","year":2022,"lang":"en","type":"other","venue":"Figshare","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Queen's University","funders":"","keywords":"Motor function; Motor system; Motor control; Affect (linguistics); Motor skill; Motor activity; Activities of daily living","score_opus":0.22733547729746015,"score_gpt":0.4974508076069547,"score_spread":0.27011533030949453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6977690332","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07997022,0.0070898673,0.0000032181833,0.000047139663,0.005240104,0.005873819,0.59406155,0.00088160275,0.30683246],"genre_scores_gemma":[0.62942845,0.000036017165,0.00016078509,0.0011388264,0.0018375182,0.0033104757,0.13047405,0.0012547522,0.23235914],"study_design_codex":"not_applicable","study_design_gemma":"observational","domain_scores_codex":[0.9973235,0.000857263,0.0003374715,0.00067934516,0.00032724923,0.00047517446],"domain_scores_gemma":[0.9987846,0.00046201856,0.00035957154,0.00021092751,0.00005251784,0.00013039047],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00029548752,0.0004222014,0.00044035033,0.00048965117,0.0003133596,0.0001573436,0.00046830732,0.00041667273,0.7108042],"category_scores_gemma":[0.00026153243,0.00045369394,0.000169787,0.00032201555,0.00003604763,0.00013291796,0.00035741137,0.0016139036,0.00080587715],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057312584,0.0014946694,0.40416953,0.00037410032,0.0002936473,0.0009725558,0.00025756028,0.000009466742,0.00012465924,0.000008466895,0.59024704,0.0019909593],"study_design_scores_gemma":[0.0016731,0.00019962642,0.59469515,0.00038966953,0.000047522775,0.000012109903,0.000117939526,0.000079328274,0.00003116013,0.0000047564063,0.4023073,0.000442354],"about_ca_topic_score_codex":0.00007777467,"about_ca_topic_score_gemma":0.00010399987,"teacher_disagreement_score":0.70999837,"about_ca_system_score_codex":0.00023836613,"about_ca_system_score_gemma":0.00015809045,"threshold_uncertainty_score":0.9999721},"labels":[],"label_agreement":null},{"id":"W7132884031","doi":"","title":"Application of quantitative structure-toxicity relationships to quinone-induced cellular oxidative stress","year":2004,"lang":"","type":"dissertation","venue":"TSpace","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Bibliographical Society of Canada","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cytotoxicity; Reactive oxygen species; Catalase; Quinone; Oxidative stress; Hepatocyte; Intracellular; Enzyme","score_opus":0.14201652831813077,"score_gpt":0.4647898375917617,"score_spread":0.3227733092736309,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7132884031","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97702473,0.0007809414,0.01256136,0.00051633664,0.0022453656,0.0030719396,0.00095573365,0.00007625173,0.0027673417],"genre_scores_gemma":[0.9929919,0.0001247556,0.002093134,0.00020564446,0.0002668934,0.00014699096,0.0022759382,0.00012116229,0.0017735426],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9940789,0.0015932177,0.0013437998,0.0014196736,0.00068197696,0.00088247925],"domain_scores_gemma":[0.9947418,0.0008237748,0.0019112257,0.00070071535,0.0011992914,0.0006232127],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0007884485,0.0010936753,0.001337546,0.0006458622,0.001029769,0.0000624686,0.0008951541,0.0017864864,0.0011099656],"category_scores_gemma":[0.00039087483,0.001205686,0.00039393432,0.0013916728,0.00035160055,0.00026419645,0.00016746293,0.0029450809,0.0002542641],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001952741,0.0013518784,0.005793316,0.0008130547,0.0010022402,0.000022635735,0.03874432,0.00292324,0.92572373,0.02010076,0.00011487153,0.0014572018],"study_design_scores_gemma":[0.0018510352,0.00090476713,0.022491978,0.00033353714,0.0009690288,0.0000040385034,0.024931863,0.0015317905,0.942499,0.0018874026,0.0014625905,0.0011330039],"about_ca_topic_score_codex":0.0006971455,"about_ca_topic_score_gemma":0.0010608803,"teacher_disagreement_score":0.018213356,"about_ca_system_score_codex":0.0005563955,"about_ca_system_score_gemma":0.0007194651,"threshold_uncertainty_score":0.9998031},"labels":[],"label_agreement":null}]}